Standard name Systematic name Name description Description
EPL1 YFL024C Subunit of NuA4, an essential histone H4/H2A acetyltransferase complex Subunit of NuA4, an essential histone H4/H2A acetyltransferase complex; conserved region at N-terminus is essential for interaction with the NPC (nucleosome core particle); required for autophagy; homologous to Drosophila Enhancer of Polycomb; coding sequence contains length polymorphisms in different strains
Visualize the interactome of EPL1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Mito 0.211 0.123 0.061
Nucleolus 0.088 NaN NaN
Nucleus 0.884 0.881 0.892
Cytoplasm NaN NaN 0.052
SpindlePole NaN NaN 0.075

GFP localization & abundance

GFP localization GFP abundance
nucleus 1110

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
EPL1 5 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
ESA1 YOR244W Catalytic subunit of the histone acetyltransferase complex (NuA4) physical 25 4 19 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Co-crystal Structure, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Co-purification, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Co-purification
EAF1 YDR359C Component of the NuA4 histone acetyltransferase complex physical 19 4 14 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Co-crystal Structure, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Co-purification
ARP4 YJL081C Nuclear actin-related protein involved in chromatin remodeling physical 16 4 14 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Co-crystal Structure, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Co-purification
YAF9 YNL107W Subunit of NuA4 histone H4 acetyltransferase and SWR1 complexes physical 15 5 14 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Co-crystal Structure, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Co-purification, Reconstituted Complex
YNG2 YHR090C Subunit of NuA4, an essential histone acetyltransferase complex physical 15 5 12 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Two-hybrid, Affinity Capture-Western, Co-crystal Structure, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Co-purification
EAF3 YPR023C Component of the Rpd3S histone deacetylase complex physical 15 4 11 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Co-crystal Structure, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Co-purification
TRA1 YHR099W Subunit of SAGA and NuA4 histone acetyltransferase complexes physical 13 4 11 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Co-crystal Structure, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Co-purification
EAF5 YEL018W Non-essential subunit of the NuA4 acetyltransferase complex physical 12 4 9 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Co-crystal Structure, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-purification
SWC4 YGR002C Component of the Swr1p complex that incorporates Htz1p into chromatin physical 11 4 10 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Co-crystal Structure, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Co-purification
EAF7 YNL136W Subunit of the NuA4 histone acetyltransferase complex physical 10 4 8 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Co-crystal Structure, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-purification
ACT1 YFL039C Actin, structural protein in cytoskeleton physical 9 3 8 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Co-crystal Structure, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
EAF6 YJR082C Subunit of the NuA4 acetyltransferase complex physical 6 4 4 Affinity Capture-MS, Co-crystal Structure, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Co-purification
HDA2 YDR295C Subunit of HDA1 histone deacetylase complex genetic 4 1 2 Synthetic Rescue, Synthetic Rescue, Synthetic Rescue, Synthetic Rescue
ARP4 YJL081C Nuclear actin-related protein involved in chromatin remodeling genetic 4 1 1 Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality
EAF1 YDR359C Component of the NuA4 histone acetyltransferase complex genetic 4 1 1 Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality
EAF5 YEL018W Non-essential subunit of the NuA4 acetyltransferase complex genetic 4 1 1 Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
EAF3 YPR023C Component of the Rpd3S histone deacetylase complex genetic 4 1 1 Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
ESA1 YOR244W Catalytic subunit of the histone acetyltransferase complex (NuA4) genetic 4 1 1 Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality
YAF9 YNL107W Subunit of NuA4 histone H4 acetyltransferase and SWR1 complexes genetic 4 1 1 Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality
YNG2 YHR090C Subunit of NuA4, an essential histone acetyltransferase complex genetic 4 1 1 Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality
SWC4 YGR002C Component of the Swr1p complex that incorporates Htz1p into chromatin genetic 4 1 1 Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes genetic 4 1 1 Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality
HST3 YOR025W Sirtuin, histone H3 deacetylase genetic 4 1 1 Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
SAS2 YMR127C Histone acetyltransferase (HAT) catalytic subunit of the SAS complex genetic 4 1 1 Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
SAS3 YBL052C Histone acetyltransferase catalytic subunit of NuA3 complex genetic 4 1 1 Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
SIR2 YDL042C Conserved NAD+ dependent histone deacetylase of the Sirtuin family genetic 4 1 1 Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
SPT8 YLR055C Subunit of the SAGA transcriptional regulatory complex genetic 4 1 1 Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality
ADA2 YDR448W Transcription coactivator genetic 4 1 1 Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality
CDC20 YGL116W Activator of anaphase-promoting complex/cyclosome (APC/C) genetic 4 1 1 Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality
ELP3 YPL086C Subunit of Elongator complex genetic 4 1 1 Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
EAF7 YNL136W Subunit of the NuA4 histone acetyltransferase complex genetic 4 1 1 Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
SWR1 YDR334W Swi2/Snf2-related ATPase genetic 3 1 2 Synthetic Lethality, Synthetic Lethality, Synthetic Lethality
HDA3 YPR179C Subunit of HDA1 histone deacetylase complex genetic 3 1 2 Synthetic Rescue, Synthetic Rescue, Synthetic Rescue
SAP30 YMR263W Component of Rpd3L histone deacetylase complex genetic 3 1 2 Synthetic Rescue, Synthetic Rescue, Synthetic Rescue
SDS3 YIL084C Component of the Rpd3L histone deacetylase complex genetic 3 1 2 Synthetic Rescue, Synthetic Rescue, Synthetic Rescue
HHF2 YNL030W Histone H4 physical 2 2 2 Affinity Capture-MS, Affinity Capture-Western
HTA2 YBL003C Histone H2A physical 2 2 2 Affinity Capture-MS, Affinity Capture-Western
HHT1 YBR010W Histone H3 physical 2 2 2 Affinity Capture-Western, Affinity Capture-MS
HHT2 YNL031C Histone H3 physical 2 2 2 Affinity Capture-Western, Affinity Capture-MS
HTB1 YDR224C Histone H2B physical 2 2 2 Affinity Capture-Western, Reconstituted Complex
SAP185 YJL098W Protein that forms a complex with the Sit4p protein phosphatase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
CTF19 YPL018W Outer kinetochore protein, needed for accurate chromosome segregation genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
CKB1 YGL019W Beta regulatory subunit of casein kinase 2 (CK2) genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
CKB2 YOR039W Beta' regulatory subunit of casein kinase 2 (CK2) genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
BRE1 YDL074C E3 ubiquitin ligase genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
APC1 YNL172W Largest subunit of the Anaphase-Promoting Complex/Cyclosome genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
APC2 YLR127C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
ASF1 YJL115W Nucleosome assembly factor genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
BDF1 YLR399C BET family transcriptional regulator genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
BEM2 YER155C Rho GTPase activating protein (RhoGAP) genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
CTF18 YMR078C Subunit of a complex with Ctf8p genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
CTK1 YKL139W Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
CDC23 YHR166C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
ELP2 YGR200C Subunit of Elongator complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
HTZ1 YOL012C Histone variant H2AZ genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
HHT1 YBR010W Histone H3 genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
HTA1 YDR225W Histone H2A genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
HDA1 YNL021W Catalytic subunit of class II HDA1 histone deacetylase complex genetic 2 1 1 Synthetic Rescue, Synthetic Rescue
PHO23 YNL097C Component of the Rpd3L histone deacetylase complex genetic 2 1 1 Synthetic Rescue, Synthetic Rescue
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes genetic 2 1 1 Synthetic Rescue, Synthetic Rescue
SIN3 YOL004W Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 2 1 1 Synthetic Rescue, Synthetic Rescue
ESC2 YDR363W Sumo-like domain protein genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
FYV6 YNL133C Protein of unknown function genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
GET1 YGL020C Subunit of the GET complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
GLO3 YER122C ADP-ribosylation factor GTPase activating protein (ARF GAP) genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
TRS85 YDR108W Component of transport protein particle (TRAPP) complex III genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
GUP1 YGL084C Plasma membrane protein involved in remodeling GPI anchors genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
HFI1 YPL254W Adaptor protein required for structural integrity of the SAGA complex genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
HOG1 YLR113W Mitogen-activated protein kinase involved in osmoregulation genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
HPC2 YBR215W Subunit of the HIR complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
HUR1 YGL168W Protein with a role in DNA repair genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
IKI3 YLR384C Subunit of Elongator complex genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
IRA2 YOL081W GTPase-activating protein genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
IWR1 YDL115C RNA polymerase II transport factor, conserved from yeast to humans genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
KTI12 YKL110C Protein that plays a role in modification of tRNA wobble nucleosides genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
LDB19 YOR322C Alpha-arrestin, Ub-ligase adaptor for Rsp5p genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
LDB7 YBL006C Component of the RSC chromatin remodeling complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
LGE1 YPL055C Protein involved in histone H2B ubiquitination genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
LRP1 YHR081W Nuclear exosome-associated nucleic acid binding protein genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
LSM1 YJL124C Lsm (Like Sm) protein genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
LTE1 YAL024C Protein similar to GDP/GTP exchange factors genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
MCM16 YPR046W Component of the Ctf19 complex and the COMA subcomplex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
MID1 YNL291C Stretch-activated Ca2+-permeable cation channel genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
MMS22 YLR320W Subunit of E3 ubiquitin ligase complex involved in replication repair genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
MNN11 YJL183W Subunit of a Golgi mannosyltransferase complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
MON2 YNL297C Protein with a role in endocytosis and vacuole integrity genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
MRC1 YCL061C S-phase checkpoint protein required for DNA replication genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
MSC1 YML128C Protein of unknown function genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
NBP2 YDR162C Protein involved in the HOG (high osmolarity glycerol) pathway genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
NGG1 YDR176W Subunit of chromatin modifying histone acetyltransferase complexes genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
NHX1 YDR456W Na+/H+ and K+/H+ exchanger genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
NIP100 YPL174C Large subunit of the dynactin complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
PDX1 YGR193C E3-binding protein of the mitochondrial pyruvate dehydrogenase complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
PEP3 YLR148W Component of CORVET membrane tethering complex genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
PEP5 YMR231W Histone E3 ligase, component of CORVET membrane tethering complex genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
PEP7 YDR323C Adaptor protein involved in vesicle-mediated vacuolar protein sorting genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
POP2 YNR052C Subunit of Ccr4-Not complex that mediates 3' to 5' mRNA deadenylation genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
PTC1 YDL006W Type 2C protein phosphatase (PP2C) genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
RAD51 YER095W Strand exchange protein genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
RAD6 YGL058W Ubiquitin-conjugating enzyme (E2) genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
RCY1 YJL204C F-box protein involved in recycling endocytosed proteins genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
REF2 YDR195W RNA-binding protein genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
RIC1 YLR039C Protein involved in retrograde transport to the cis-Golgi network genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
RMD1 YDL001W Cytoplasmic protein required for sporulation genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
RRD1 YIL153W Peptidyl-prolyl cis/trans-isomerase genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
RSC1 YGR056W Component of the RSC chromatin remodeling complex genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
RSC2 YLR357W Component of the RSC chromatin remodeling complex genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
RTT103 YDR289C Protein involved in transcription termination by RNA polymerase II genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
RUD3 YOR216C Golgi matrix protein genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
SAC3 YDR159W mRNA export factor genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
SAS4 YDR181C Subunit of the SAS complex (Sas2p, Sas4p, Sas5p) genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
SAS5 YOR213C Subunit of the SAS complex (Sas2p, Sas4p, Sas5p) genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
SET2 YJL168C Histone methyltransferase with a role in transcriptional elongation genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
SGF29 YCL010C Component of the HAT/Core module of the SAGA, SLIK, and ADA complexes genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
SGO1 YOR073W Component of the spindle checkpoint genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
SIC1 YLR079W Cyclin-dependent kinase inhibitor (CKI) genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
SIR3 YLR442C Silencing protein genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
SIR4 YDR227W SIR protein involved in assembly of silent chromatin domains genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
SLX5 YDL013W Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
SMI1 YGR229C Protein involved in the regulation of cell wall synthesis genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
SNF12 YNR023W 73 kDa subunit of the SWI/SNF chromatin remodeling complex genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
SNF2 YOR290C Catalytic subunit of the SWI/SNF chromatin remodeling complex genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
SNF6 YHL025W Subunit of the SWI/SNF chromatin remodeling complex genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
SPT20 YOL148C Subunit of the SAGA transcriptional regulatory complex genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
SPT3 YDR392W Subunit of the SAGA and SAGA-like transcriptional regulatory complexes genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
SPT7 YBR081C Subunit of the SAGA transcriptional regulatory complex genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
SSN2 YDR443C Subunit of the RNA polymerase II mediator complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
SSN3 YPL042C Component of the RNA polymerase II mediator complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
SSN8 YNL025C Cyclin-like component of RNA polymerase II holoenzyme genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
STP22 YCL008C Component of the ESCRT-I complex genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
SWA2 YDR320C Auxilin-like protein involved in vesicular transport genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
SWC3 YAL011W Protein of unknown function genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
SWC5 YBR231C Component of the SWR1 complex genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
SWD1 YAR003W Subunit of the COMPASS (Set1C) complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
SWD3 YBR175W Essential subunit of the COMPASS (Set1C) complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
SWI6 YLR182W Transcription cofactor genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
SWM1 YDR260C Subunit of the anaphase-promoting complex (APC) genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
TAF14 YPL129W Subunit of TFIID, TFIIF, INO80, SWI/SNF, and NuA3 complexes genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
THP1 YOL072W Nuclear pore-associated protein genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
TOF1 YNL273W Subunit of a replication-pausing checkpoint complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
TPM1 YNL079C Major isoform of tropomyosin genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
TRM9 YML014W tRNA methyltransferase genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
TVP18 YMR071C Integral membrane protein genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
UBC4 YBR082C Ubiquitin-conjugating enzyme (E2) genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
UTR1 YJR049C ATP-NADH kinase genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
VMA4 YOR332W Subunit E of the V1 domain of the vacuolar H+-ATPase (V-ATPase) genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
VMA5 YKL080W Subunit C of the V1 peripheral membrane domain of V-ATPase genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
VMA7 YGR020C Subunit F of the V1 peripheral membrane domain of V-ATPase genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
VPH2 YKL119C Integral membrane protein required for V-ATPase function genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
VPS1 YKR001C Dynamin-like GTPase required for vacuolar sorting genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
VPS15 YBR097W Serine/threonine protein kinase involved in vacuolar protein sorting genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
VPS20 YMR077C Myristoylated subunit of the ESCRT-III complex genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
VPS25 YJR102C Component of the ESCRT-II complex genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
VPS27 YNR006W Endosomal protein that forms a complex with Hse1p genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
VPS33 YLR396C ATP-binding protein that is a subunit of the HOPS and CORVET complexes genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
VPS34 YLR240W Phosphatidylinositol (PI) 3-kinase that synthesizes PI-3-phosphate genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
VPS45 YGL095C Protein of the Sec1p/Munc-18 family genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
VPS51 YKR020W Component of the GARP (Golgi-associated retrograde protein) complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
VPS53 YJL029C Component of the GARP (Golgi-associated retrograde protein) complex genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
VPS64 YDR200C Protein required for cytoplasm to vacuole targeting of proteins genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
VPS71 YML041C Nucleosome-binding component of the SWR1 complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
YNG1 YOR064C Subunit of the NuA3 histone acetyltransferase complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
MOT3 YMR070W Transcriptional repressor, activator genetic 2 1 1 Synthetic Rescue, Synthetic Rescue
COG8 YML071C Component of the conserved oligomeric Golgi complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
END3 YNL084C EH domain-containing protein involved in endocytosis genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
ANP1 YEL036C Subunit of the alpha-1,6 mannosyltransferase complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
DRS2 YAL026C Trans-golgi network aminophospholipid translocase (flippase) genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
BRE2 YLR015W Subunit of COMPASS (Set1C) complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
DYN2 YDR424C Cytoplasmic light chain dynein, microtubule motor protein genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
ACS2 YLR153C Acetyl-coA synthetase isoform genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
DIA2 YOR080W Origin-binding F-box protein genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
CTF4 YPR135W Chromatin-associated protein genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
AHC1 YOR023C Subunit of the Ada histone acetyltransferase complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
CTK3 YML112W Gamma subunit of C-terminal domain kinase I genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
CSM3 YMR048W Replication fork associated factor genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
ELP6 YMR312W Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
APC11 YDL008W Catalytic core subunit, Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
CDC26 YFR036W Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
COG7 YGL005C Component of the conserved oligomeric Golgi complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
COG6 YNL041C Component of the conserved oligomeric Golgi complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
COG5 YNL051W Component of the conserved oligomeric Golgi complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
ELP4 YPL101W Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
ARP6 YLR085C Actin-related protein that binds nucleosomes genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
CTK2 YJL006C Beta subunit of C-terminal domain kinase I (CTDK-I) genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
CSF1 YLR087C Protein with structural similarity to lipid transport protein Vps13p genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
DCC1 YCL016C Subunit of a complex with Ctf8p and Ctf18p genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
ARV1 YLR242C Cortical ER protein genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
DAP2 YHR028C Dipeptidyl aminopeptidase genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
CDC50 YCR094W Endosomal protein that interacts with phospholipid flippase Drs2p genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
DFG16 YOR030W Probable multiple transmembrane protein genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
DPL1 YDR294C Dihydrosphingosine phosphate lyase genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CBF1 YJR060W Basic helix-loop-helix (bHLH) protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
FKH2 YNL068C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MED2 YDL005C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RPN4 YDL020C Transcription factor that stimulates expression of proteasome genes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RAP1 YNL216W Essential DNA-binding transcription regulator that binds many loci regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAP6 YDR259C Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
REB1 YBR049C RNA polymerase I enhancer binding protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SPT3 YDR392W Subunit of the SAGA and SAGA-like transcriptional regulatory complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
FHL1 YPR104C Regulator of ribosomal protein (RP) transcription regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ARG80 YMR042W Transcription factor involved in regulating arginine-responsive genes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
GLN3 YER040W Transcriptional activator in nitrogen catabolite repression system regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ARG81 YML099C Zinc finger transcription factor involved in arginine-responsive genes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
ECM16 YMR128W Essential DEAH-box ATP-dependent RNA helicase specific to U3 snoRNP physical 1 1 1 Affinity Capture-MS
GCN4 YEL009C bZIP transcriptional activator of amino acid biosynthetic genes physical 1 1 1 Reconstituted Complex
HTZ1 YOL012C Histone variant H2AZ physical 1 1 1 Affinity Capture-MS
HMO1 YDR174W Chromatin associated high mobility group (HMG) family member physical 1 1 1 Affinity Capture-MS
RSC8 YFR037C Component of the RSC chromatin remodeling complex physical 1 1 1 Affinity Capture-MS
YAP1 YML007W Basic leucine zipper (bZIP) transcription factor physical 1 1 1 Affinity Capture-MS
RPT6 YGL048C ATPase of the 19S regulatory particle of the 26S proteasome physical 1 1 1 Affinity Capture-Western
SPC25 YER018C Component of the kinetochore-associated Ndc80 complex physical 1 1 1 Two-hybrid
HEK2 YBL032W RNA binding protein involved in asymmetric localization of ASH1 mRNA physical 1 1 1 Affinity Capture-RNA
MOT1 YPL082C Essential protein involved in regulation of transcription physical 1 1 1 Affinity Capture-MS
IFH1 YLR223C Coactivator, regulates transcription of ribosomal protein (RP) genes physical 1 1 1 Reconstituted Complex
GAL4 YPL248C DNA-binding transcription factor required for activating GAL genes physical 1 1 1 Reconstituted Complex
RCK1 YGL158W Protein kinase involved in oxidative stress response physical 1 1 1 Affinity Capture-MS
HHF1 YBR009C Histone H4 physical 1 1 1 Affinity Capture-Western
HTA1 YDR225W Histone H2A physical 1 1 1 Affinity Capture-Western
HTB2 YBL002W Histone H2B physical 1 1 1 Affinity Capture-Western
SBP1 YHL034C Protein that binds eIF4G and has a role in repression of translation physical 1 1 1 Affinity Capture-RNA
SPT10 YJL127C Histone H3 acetylase with a role in transcriptional regulation physical 1 1 1 Affinity Capture-MS
RPC82 YPR190C RNA polymerase III subunit C82 physical 1 1 1 Affinity Capture-MS
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
MPT5 YGL178W mRNA-binding protein of the PUF family physical 1 1 1 Affinity Capture-RNA
PUB1 YNL016W Poly (A)+ RNA-binding protein physical 1 1 1 Affinity Capture-MS
CRM1 YGR218W Nuclear export factor, exportin physical 1 1 1 Affinity Capture-MS
ATG3 YNR007C E2-like enzyme physical 1 1 1 Affinity Capture-Western
CAF20 YOR276W Phosphoprotein of the mRNA cap-binding complex physical 1 1 1 Affinity Capture-RNA
APJ1 YNL077W Hsp40 chaperone with a role in SUMO-mediated protein degradation physical 1 1 1 Affinity Capture-MS