GEnome-wide tool for Multi-scale Modeling
data Extraction and Representation
for Saccharomyces cerevisiae

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.

Standard name	Systematic name	Name description	Type	#Experiments	#Methods	#Publications	Evidence
EPL1	YFL024C	Subunit of NuA4, an essential histone H4/H2A acetyltransferase complex	physical	25	4	19	Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Co-crystal Structure, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Co-purification, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Co-purification
TRA1	YHR099W	Subunit of SAGA and NuA4 histone acetyltransferase complexes	physical	16	3	15	Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Co-purification, Co-purification, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Co-purification
ARP4	YJL081C	Nuclear actin-related protein involved in chromatin remodeling	physical	14	5	11	Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS, Co-purification
EAF1	YDR359C	Component of the NuA4 histone acetyltransferase complex	physical	12	4	11	Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Co-purification, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Co-purification, Reconstituted Complex
YAF9	YNL107W	Subunit of NuA4 histone H4 acetyltransferase and SWR1 complexes	physical	11	3	10	Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Co-purification
EAF3	YPR023C	Component of the Rpd3S histone deacetylase complex	physical	11	4	9	Affinity Capture-MS, Reconstituted Complex, Co-purification, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Co-purification
RPD3	YNL330C	Histone deacetylase, component of both the Rpd3S and Rpd3L complexes	genetic	11	3	6	Synthetic Rescue, Synthetic Rescue, Synthetic Rescue, Synthetic Rescue, Phenotypic Suppression, Synthetic Rescue, Phenotypic Suppression, Synthetic Rescue, Phenotypic Suppression, Phenotypic Suppression, Synthetic Growth Defect
EAF6	YJR082C	Subunit of the NuA4 acetyltransferase complex	genetic	11	3	4	Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
EAF5	YEL018W	Non-essential subunit of the NuA4 acetyltransferase complex	physical	10	3	8	Co-purification, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Co-purification, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western
SIR2	YDL042C	Conserved NAD+ dependent histone deacetylase of the Sirtuin family	genetic	10	4	6	Dosage Rescue, Dosage Rescue, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Phenotypic Suppression, Phenotypic Suppression, Synthetic Growth Defect, Synthetic Rescue
EAF7	YNL136W	Subunit of the NuA4 histone acetyltransferase complex	genetic	10	3	3	Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic
SWC4	YGR002C	Component of the Swr1p complex that incorporates Htz1p into chromatin	physical	9	3	9	Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-purification, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Co-purification
ACT1	YFL039C	Actin, structural protein in cytoskeleton	physical	9	3	9	Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-purification, Affinity Capture-MS
EAF7	YNL136W	Subunit of the NuA4 histone acetyltransferase complex	physical	9	3	6	Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Co-purification, Affinity Capture-MS, Affinity Capture-Western
GCN5	YGR252W	Catalytic subunit of ADA and SAGA histone acetyltransferase complexes	genetic	9	3	4	Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect, Phenotypic Enhancement, Synthetic Lethality
RTT109	YLL002W	Histone acetyltransferase	genetic	9	3	2	Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Negative Genetic
YNG2	YHR090C	Subunit of NuA4, an essential histone acetyltransferase complex	physical	8	3	8	Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-purification
HHF1	YBR009C	Histone H4	physical	8	3	8	Biochemical Activity, Biochemical Activity, Co-localization, Biochemical Activity, Biochemical Activity, Affinity Capture-MS, Biochemical Activity, Biochemical Activity
SDS3	YIL084C	Component of the Rpd3L histone deacetylase complex	genetic	8	2	5	Synthetic Rescue, Phenotypic Suppression, Synthetic Rescue, Phenotypic Suppression, Synthetic Rescue, Phenotypic Suppression, Synthetic Rescue, Synthetic Rescue
SPT8	YLR055C	Subunit of the SAGA transcriptional regulatory complex	genetic	8	2	1	Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
EAF5	YEL018W	Non-essential subunit of the NuA4 acetyltransferase complex	genetic	8	2	1	Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
HHF2	YNL030W	Histone H4	physical	7	2	7	Biochemical Activity, Biochemical Activity, Co-localization, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity
EAF6	YJR082C	Subunit of the NuA4 acetyltransferase complex	physical	7	3	6	Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-purification, Affinity Capture-MS, Affinity Capture-Western
HDA1	YNL021W	Catalytic subunit of class II HDA1 histone deacetylase complex	genetic	7	4	4	Synthetic Rescue, Synthetic Rescue, Synthetic Rescue, Phenotypic Enhancement, Phenotypic Suppression, Positive Genetic, Synthetic Rescue
SWC4	YGR002C	Component of the Swr1p complex that incorporates Htz1p into chromatin	genetic	7	2	3	Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic
EAF3	YPR023C	Component of the Rpd3S histone deacetylase complex	genetic	7	2	3	Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
HHT1	YBR010W	Histone H3	physical	6	3	6	Biochemical Activity, Biochemical Activity, Affinity Capture-MS, Reconstituted Complex, Biochemical Activity, Biochemical Activity
SGS1	YMR190C	RecQ family nucleolar DNA helicase	genetic	6	3	5	Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Synthetic Lethality, Negative Genetic, Negative Genetic
HOS2	YGL194C	Histone deacetylase and subunit of Set3 and Rpd3L complexes	genetic	6	3	4	Synthetic Rescue, Synthetic Rescue, Synthetic Growth Defect, Phenotypic Suppression, Synthetic Rescue, Phenotypic Suppression
ASF1	YJL115W	Nucleosome assembly factor	genetic	6	2	4	Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic
RAD6	YGL058W	Ubiquitin-conjugating enzyme (E2)	genetic	6	2	2	Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Lethality, Synthetic Lethality
VPS8	YAL002W	Membrane-binding component of the CORVET complex	genetic	6	2	2	Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Lethality, Synthetic Lethality
SWD1	YAR003W	Subunit of the COMPASS (Set1C) complex	genetic	6	2	2	Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Lethality, Synthetic Lethality
CDC20	YGL116W	Activator of anaphase-promoting complex/cyclosome (APC/C)	genetic	6	2	2	Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic
HTA1	YDR225W	Histone H2A	physical	5	2	5	Biochemical Activity, Biochemical Activity, Affinity Capture-MS, Biochemical Activity, Biochemical Activity
HTA2	YBL003C	Histone H2A	physical	5	2	5	Biochemical Activity, Affinity Capture-MS, Affinity Capture-MS, Biochemical Activity, Biochemical Activity
PHO23	YNL097C	Component of the Rpd3L histone deacetylase complex	genetic	5	3	3	Synthetic Rescue, Synthetic Rescue, Synthetic Rescue, Phenotypic Suppression, Positive Genetic
CSF1	YLR087C	Protein with structural similarity to lipid transport protein Vps13p	genetic	5	3	3	Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Lethality, Synthetic Lethality, Negative Genetic
CKB2	YOR039W	Beta' regulatory subunit of casein kinase 2 (CK2)	genetic	5	2	3	Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
SLX8	YER116C	Subunit of Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex	genetic	5	2	3	Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
LYS20	YDL182W	Homocitrate synthase isozyme and functions in DNA repair	genetic	5	2	3	Dosage Rescue, Phenotypic Suppression, Dosage Rescue, Dosage Rescue, Phenotypic Suppression
DIA2	YOR080W	Origin-binding F-box protein	genetic	5	2	3	Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
BRE2	YLR015W	Subunit of COMPASS (Set1C) complex	genetic	5	1	3	Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
LSB3	YFR024C-A	Protein containing a C-terminal SH3 domain	genetic	5	3	2	Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Lethality, Synthetic Lethality, Negative Genetic
MSC1	YML128C	Protein of unknown function	genetic	5	3	2	Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Lethality, Synthetic Lethality, Negative Genetic
RGP1	YDR137W	Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p)	genetic	5	3	2	Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
SAC7	YDR389W	GTPase activating protein (GAP) for Rho1p	genetic	5	3	2	Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
SWI6	YLR182W	Transcription cofactor	genetic	5	3	2	Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Lethality, Synthetic Lethality, Positive Genetic
CDC23	YHR166C	Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C)	genetic	5	3	2	Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
ARP6	YLR085C	Actin-related protein that binds nucleosomes	genetic	5	3	2	Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Lethality, Synthetic Lethality, Negative Genetic
ARP4	YJL081C	Nuclear actin-related protein involved in chromatin remodeling	genetic	5	2	2	Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Negative Genetic
YAF9	YNL107W	Subunit of NuA4 histone H4 acetyltransferase and SWR1 complexes	genetic	5	1	2	Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality
HHT2	YNL031C	Histone H3	physical	4	2	4	Biochemical Activity, Biochemical Activity, Reconstituted Complex, Biochemical Activity
MRE11	YMR224C	Nuclease subunit of the MRX complex with Rad50p and Xrs2p	genetic	4	3	3	Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Lethality, Negative Genetic
SIF2	YBR103W	WD40 repeat-containing subunit of Set3C histone deacetylase complex	genetic	4	3	3	Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Synthetic Rescue
TPM1	YNL079C	Major isoform of tropomyosin	genetic	4	2	3	Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic
SGF73	YGL066W	Subunit of DUBm module of SAGA and SLIK	genetic	4	2	3	Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic
SLX5	YDL013W	Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex	genetic	4	2	3	Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic
OPI1	YHL020C	Transcriptional regulator of a variety of genes	genetic	4	2	3	Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic
SAS4	YDR181C	Subunit of the SAS complex (Sas2p, Sas4p, Sas5p)	genetic	4	2	3	Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic
YAP1	YML007W	Basic leucine zipper (bZIP) transcription factor	physical	4	1	3	Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RSC2	YLR357W	Component of the RSC chromatin remodeling complex	genetic	4	3	2	Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect, Phenotypic Enhancement
HTZ1	YOL012C	Histone variant H2AZ	genetic	4	2	2	Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Lethality, Synthetic Lethality
SET2	YJL168C	Histone methyltransferase with a role in transcriptional elongation	genetic	4	2	2	Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect, Synthetic Growth Defect
YPT6	YLR262C	Rab family GTPase	genetic	4	2	2	Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Lethality, Synthetic Lethality
VPS51	YKR020W	Component of the GARP (Golgi-associated retrograde protein) complex	genetic	4	2	2	Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic
SWR1	YDR334W	Swi2/Snf2-related ATPase	genetic	4	2	2	Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Lethality, Synthetic Lethality
COG6	YNL041C	Component of the conserved oligomeric Golgi complex	genetic	4	2	2	Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect, Synthetic Growth Defect
CLA4	YNL298W	Cdc42p-activated signal transducing kinase	genetic	4	2	2	Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Lethality, Synthetic Lethality
RAD52	YML032C	Protein involved in homologous recombination	genetic	4	1	2	Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
SWD3	YBR175W	Essential subunit of the COMPASS (Set1C) complex	genetic	4	1	2	Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
ISW1	YBR245C	ATPase subunit of imitation-switch (ISWI) class chromatin remodelers	genetic	4	1	2	Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
NBP2	YDR162C	Protein involved in the HOG (high osmolarity glycerol) pathway	genetic	4	1	2	Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
VAM7	YGL212W	Vacuolar SNARE protein	genetic	4	1	2	Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
LGE1	YPL055C	Protein involved in histone H2B ubiquitination	genetic	4	1	2	Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
MMS1	YPR164W	Subunit of E3 ubiquitin ligase complex involved in replication repair	genetic	4	1	2	Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
RAD50	YNL250W	Subunit of MRX complex with Mre11p and Xrs2p	genetic	4	1	2	Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
SAP30	YMR263W	Component of Rpd3L histone deacetylase complex	genetic	4	1	2	Synthetic Rescue, Synthetic Rescue, Synthetic Rescue, Synthetic Rescue
BRE1	YDL074C	E3 ubiquitin ligase	genetic	4	1	2	Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
COG5	YNL051W	Component of the conserved oligomeric Golgi complex	genetic	4	1	2	Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
MDM32	YOR147W	Mitochondrial inner membrane protein with similarity to Mdm31p	genetic	4	2	1	Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Lethality, Synthetic Lethality
MON1	YGL124C	Subunit of a heterodimeric guanine nucleotide exchange factor (GEF)	genetic	4	2	1	Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Lethality, Synthetic Lethality
MRPL24	YMR193W	Mitochondrial ribosomal protein of the large subunit	genetic	4	2	1	Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Lethality, Synthetic Lethality
MSR1	YHR091C	Mitochondrial arginyl-tRNA synthetase	genetic	4	2	1	Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Lethality, Synthetic Lethality
NPL4	YBR170C	Substrate-recruiting cofactor of the Cdc48p-Npl4p-Ufd1p segregase	genetic	4	2	1	Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect, Synthetic Growth Defect
PEP7	YDR323C	Adaptor protein involved in vesicle-mediated vacuolar protein sorting	genetic	4	2	1	Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Lethality, Synthetic Lethality
PFD1	YJL179W	Subunit of heterohexameric prefoldin	genetic	4	2	1	Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Lethality, Synthetic Lethality
PHO86	YJL117W	Endoplasmic reticulum (ER) resident protein	genetic	4	2	1	Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect, Synthetic Growth Defect
RIM101	YHL027W	Cys2His2 zinc-finger transcriptional repressor	genetic	4	2	1	Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Lethality, Synthetic Lethality
RUD3	YOR216C	Golgi matrix protein	genetic	4	2	1	Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Lethality, Synthetic Lethality
SHE4	YOR035C	Protein containing a UCS (UNC-45/CRO1/SHE4) domain	genetic	4	2	1	Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Lethality, Synthetic Lethality
SIS2	YKR072C	Negative regulatory subunit of protein phosphatase 1 (Ppz1p)	genetic	4	2	1	Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect, Synthetic Growth Defect
SNF12	YNR023W	73 kDa subunit of the SWI/SNF chromatin remodeling complex	genetic	4	2	1	Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Lethality, Synthetic Lethality
SNF5	YBR289W	Subunit of the SWI/SNF chromatin remodeling complex	genetic	4	2	1	Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Lethality, Synthetic Lethality
SNF8	YPL002C	Component of the ESCRT-II complex	genetic	4	2	1	Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect, Synthetic Growth Defect
SPT2	YER161C	Protein involved in negative regulation of transcription	genetic	4	2	1	Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect, Synthetic Growth Defect
SSN8	YNL025C	Cyclin-like component of RNA polymerase II holoenzyme	genetic	4	2	1	Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Lethality, Synthetic Lethality
TAX4	YJL083W	EH domain-containing protein	genetic	4	2	1	Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect, Synthetic Growth Defect
VMA22	YHR060W	Protein that is required for vacuolar H+-ATPase (V-ATPase) function	genetic	4	2	1	Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Lethality, Synthetic Lethality
VMA8	YEL051W	Subunit D of the V1 peripheral membrane domain of V-ATPase	genetic	4	2	1	Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Lethality, Synthetic Lethality
VPH2	YKL119C	Integral membrane protein required for V-ATPase function	genetic	4	2	1	Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect, Synthetic Growth Defect
VPS1	YKR001C	Dynamin-like GTPase required for vacuolar sorting	genetic	4	2	1	Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect, Synthetic Growth Defect
VPS4	YPR173C	AAA-ATPase involved in multivesicular body (MVB) protein sorting	genetic	4	2	1	Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect, Synthetic Growth Defect
YBT1	YLL048C	Transporter of the ATP-binding cassette (ABC) family	genetic	4	2	1	Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Lethality, Synthetic Lethality
ARC18	YLR370C	Subunit of the ARP2/3 complex	genetic	4	2	1	Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect, Synthetic Growth Defect
DBF2	YGR092W	Ser/Thr kinase involved in transcription and stress response	genetic	4	2	1	Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect, Synthetic Growth Defect
DID4	YKL002W	Class E Vps protein of the ESCRT-III complex	genetic	4	2	1	Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Lethality, Synthetic Lethality
CDC26	YFR036W	Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C)	genetic	4	2	1	Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect, Synthetic Growth Defect
YNG2	YHR090C	Subunit of NuA4, an essential histone acetyltransferase complex	genetic	4	1	1	Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality
HDA3	YPR179C	Subunit of HDA1 histone deacetylase complex	genetic	4	1	1	Synthetic Rescue, Synthetic Rescue, Synthetic Rescue, Synthetic Rescue
HST3	YOR025W	Sirtuin, histone H3 deacetylase	genetic	4	1	1	Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
SAS2	YMR127C	Histone acetyltransferase (HAT) catalytic subunit of the SAS complex	genetic	4	1	1	Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
SAS3	YBL052C	Histone acetyltransferase catalytic subunit of NuA3 complex	genetic	4	1	1	Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
EAF1	YDR359C	Component of the NuA4 histone acetyltransferase complex	genetic	4	1	1	Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality
EPL1	YFL024C	Subunit of NuA4, an essential histone H4/H2A acetyltransferase complex	genetic	4	1	1	Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality
ADA2	YDR448W	Transcription coactivator	genetic	4	1	1	Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality
ELP3	YPL086C	Subunit of Elongator complex	genetic	4	1	1	Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
SET1	YHR119W	Histone methyltransferase, subunit of the COMPASS (Set1C) complex	genetic	3	3	3	Phenotypic Suppression, Synthetic Growth Defect, Negative Genetic
HST1	YOL068C	NAD(+)-dependent histone deacetylase	genetic	3	2	3	Phenotypic Suppression, Phenotypic Suppression, Synthetic Rescue
DEP1	YAL013W	Component of the Rpd3L histone deacetylase complex	genetic	3	2	3	Synthetic Rescue, Positive Genetic, Synthetic Rescue
HHT1	YBR010W	Histone H3	genetic	3	2	2	Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect
LSM1	YJL124C	Lsm (Like Sm) protein	genetic	3	2	2	Synthetic Growth Defect, Synthetic Growth Defect, Positive Genetic
RPN4	YDL020C	Transcription factor that stimulates expression of proteasome genes	genetic	3	2	2	Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
MRC1	YCL061C	S-phase checkpoint protein required for DNA replication	genetic	3	2	2	Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
NUP120	YKL057C	Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC)	genetic	3	2	2	Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
RTF1	YGL244W	Subunit of RNAPII-associated chromatin remodeling Paf1 complex	genetic	3	2	2	Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
YTA7	YGR270W	Chromatin-binding ATPase that regulates histone gene expression	genetic	3	2	2	Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
RTT101	YJL047C	Cullin subunit of a Roc1p-dependent E3 ubiquitin ligase complex	genetic	3	2	2	Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
SNT1	YCR033W	Set3C histone deacetylase scaffold	genetic	3	2	2	Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Rescue
GET2	YER083C	Subunit of the GET complex	genetic	3	2	2	Synthetic Lethality, Synthetic Lethality, Negative Genetic
HOM6	YJR139C	Homoserine dehydrogenase (L-homoserine:NADP oxidoreductase)	genetic	3	2	2	Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
HRD3	YLR207W	ER membrane protein that plays a central role in ERAD	genetic	3	2	2	Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
IKI3	YLR384C	Subunit of Elongator complex	genetic	3	2	2	Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
MON2	YNL297C	Protein with a role in endocytosis and vacuole integrity	genetic	3	2	2	Synthetic Lethality, Synthetic Lethality, Negative Genetic
PAT1	YCR077C	Deadenylation-dependent mRNA-decapping factor	genetic	3	2	2	Synthetic Growth Defect, Synthetic Growth Defect, Positive Genetic
RIM21	YNL294C	pH sensor molecule, component of the RIM101 pathway	genetic	3	2	2	Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
RIM8	YGL045W	Protein involved in proteolytic activation of Rim101p	genetic	3	2	2	Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
SAC1	YKL212W	Phosphatidylinositol phosphate phosphatase	genetic	3	2	2	Synthetic Lethality, Synthetic Lethality, Positive Genetic
SEC72	YLR292C	Non-essential subunit of Sec63 complex	genetic	3	2	2	Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
SWC3	YAL011W	Protein of unknown function	genetic	3	2	2	Synthetic Lethality, Synthetic Lethality, Positive Genetic
SWC5	YBR231C	Component of the SWR1 complex	genetic	3	2	2	Synthetic Lethality, Synthetic Lethality, Positive Genetic
SWI4	YER111C	DNA binding component of the SBF complex (Swi4p-Swi6p)	genetic	3	2	2	Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
VPS27	YNR006W	Endosomal protein that forms a complex with Hse1p	genetic	3	2	2	Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
VPS41	YDR080W	Subunit of the HOPS endocytic tethering complex	genetic	3	2	2	Synthetic Growth Defect, Synthetic Growth Defect, Positive Genetic
VPS72	YDR485C	Htz1p-binding component of the SWR1 complex	genetic	3	2	2	Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
YDJ1	YNL064C	Type I HSP40 co-chaperone	genetic	3	2	2	Synthetic Lethality, Synthetic Lethality, Negative Genetic
RCO1	YMR075W	Essential component of the Rpd3S histone deacetylase complex	genetic	3	2	2	Synthetic Growth Defect, Phenotypic Suppression, Phenotypic Suppression
BMH1	YER177W	14-3-3 protein, major isoform	physical	3	2	2	Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS
BMH1	YER177W	14-3-3 protein, major isoform	genetic	3	2	2	Synthetic Lethality, Synthetic Growth Defect, Synthetic Growth Defect
CTK1	YKL139W	Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I)	genetic	3	2	2	Synthetic Lethality, Synthetic Lethality, Positive Genetic
ATG3	YNR007C	E2-like enzyme	physical	3	2	2	Biochemical Activity, Biochemical Activity, Affinity Capture-Western
ARP8	YOR141C	Nuclear actin-related protein involved in chromatin remodeling	genetic	3	2	2	Synthetic Growth Defect, Synthetic Growth Defect, Phenotypic Suppression
DRS2	YAL026C	Trans-golgi network aminophospholipid translocase (flippase)	genetic	3	2	2	Synthetic Lethality, Synthetic Lethality, Negative Genetic
CTF4	YPR135W	Chromatin-associated protein	genetic	3	2	2	Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
ELG1	YOR144C	Subunit of an alternative replication factor C complex	genetic	3	2	2	Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Lethality
BUB3	YOR026W	Kinetochore checkpoint WD40 repeat protein	genetic	3	2	2	Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
CSM3	YMR048W	Replication fork associated factor	genetic	3	2	2	Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
ELP6	YMR312W	Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex	genetic	3	2	2	Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
APC11	YDL008W	Catalytic core subunit, Anaphase-Promoting Complex/Cyclosome (APC/C)	genetic	3	2	2	Synthetic Lethality, Synthetic Lethality, Negative Genetic
BTS1	YPL069C	Geranylgeranyl diphosphate synthase (GGPPS)	genetic	3	2	2	Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
RAD51	YER095W	Strand exchange protein	genetic	3	1	2	Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
SDC1	YDR469W	Subunit of the COMPASS (Set1C) complex	genetic	3	1	2	Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
UBC4	YBR082C	Ubiquitin-conjugating enzyme (E2)	genetic	3	1	2	Negative Genetic, Negative Genetic, Negative Genetic
BDF1	YLR399C	BET family transcriptional regulator	genetic	3	1	2	Synthetic Lethality, Synthetic Lethality, Synthetic Lethality
UBC13	YDR092W	E2 ubiquitin-conjugating enzyme	genetic	3	3	1	Phenotypic Suppression, Synthetic Growth Defect, Phenotypic Enhancement
RAP1	YNL216W	Essential DNA-binding transcription regulator that binds many loci	physical	3	2	1	Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex
ACT1	YFL039C	Actin, structural protein in cytoskeleton	genetic	3	2	1	Positive Genetic, Positive Genetic, Negative Genetic
CDC73	YLR418C	Component of the Paf1p complex	genetic	2	2	2	Synthetic Lethality, Positive Genetic
HHT2	YNL031C	Histone H3	genetic	2	2	2	Synthetic Growth Defect, Synthetic Rescue
HHF2	YNL030W	Histone H4	genetic	2	2	2	Synthetic Rescue, Phenotypic Suppression
SPT16	YGL207W	Subunit of the heterodimeric FACT complex (Spt16p-Pob3p)	genetic	2	2	2	Synthetic Growth Defect, Synthetic Lethality
MSN4	YKL062W	Stress-responsive transcriptional activator	physical	2	2	2	Reconstituted Complex, Affinity Capture-MS
HTB1	YDR224C	Histone H2B	physical	2	2	2	Biochemical Activity, Reconstituted Complex
SBP1	YHL034C	Protein that binds eIF4G and has a role in repression of translation	physical	2	2	2	Affinity Capture-RNA, Affinity Capture-MS
SSB2	YNL209W	Cytoplasmic ATPase that is a ribosome-associated molecular chaperone	physical	2	2	2	Affinity Capture-MS, Co-purification
ADH1	YOL086C	Alcohol dehydrogenase	physical	2	2	2	Affinity Capture-MS, Co-fractionation
CNM67	YNL225C	Component of the spindle pole body outer plaque	physical	2	2	2	Biochemical Activity, Affinity Capture-MS
FKH1	YIL131C	Forkhead family transcription factor	regulation	2	1	2	chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence
HPC2	YBR215W	Subunit of the HIR complex	genetic	2	1	2	Negative Genetic, Negative Genetic
HPT1	YDR399W	Dimeric hypoxanthine-guanine phosphoribosyltransferase	genetic	2	1	2	Negative Genetic, Negative Genetic
HTD2	YHR067W	Mitochondrial 3-hydroxyacyl-thioester dehydratase	genetic	2	1	2	Negative Genetic, Negative Genetic
FLX1	YIL134W	Mitochondrial flavin adenine dinucleotide transporter	genetic	2	1	2	Negative Genetic, Negative Genetic
MEU1	YLR017W	Methylthioadenosine phosphorylase (MTAP)	genetic	2	1	2	Negative Genetic, Negative Genetic
SOK2	YMR016C	Nuclear protein that negatively regulates pseudohyphal differentiation	genetic	2	1	2	Negative Genetic, Negative Genetic
OCA1	YNL099C	Putative protein tyrosine phosphatase	genetic	2	1	2	Negative Genetic, Negative Genetic
NST1	YNL091W	Translational inhibitor and suppressor of proteasome-assembly defects	genetic	2	1	2	Negative Genetic, Negative Genetic
MET22	YOL064C	Bisphosphate-3'-nucleotidase	genetic	2	1	2	Negative Genetic, Negative Genetic
FUM1	YPL262W	Fumarase	genetic	2	1	2	Negative Genetic, Negative Genetic
SEC14	YMR079W	Phosphatidylinositol/phosphatidylcholine transfer protein	genetic	2	1	2	Synthetic Growth Defect, Synthetic Growth Defect
ARO1	YDR127W	Pentafunctional arom protein	genetic	2	1	2	Negative Genetic, Negative Genetic
ATG3	YNR007C	E2-like enzyme	genetic	2	1	2	Negative Genetic, Negative Genetic
BRR1	YPR057W	snRNP protein component of spliceosomal snRNPs	genetic	2	1	2	Negative Genetic, Negative Genetic
CSM1	YCR086W	Nucleolar protein that mediates homolog segregation during meiosis I	genetic	2	1	2	Negative Genetic, Negative Genetic
AIM4	YBR194W	Protein proposed to be associated with the nuclear pore complex	genetic	2	1	2	Negative Genetic, Negative Genetic
ELO2	YCR034W	Fatty acid elongase, involved in sphingolipid biosynthesis	genetic	2	1	2	Negative Genetic, Negative Genetic
CPR7	YJR032W	Peptidyl-prolyl cis-trans isomerase (cyclophilin)	genetic	2	1	2	Negative Genetic, Negative Genetic
ARO2	YGL148W	Bifunctional chorismate synthase and flavin reductase	genetic	2	1	2	Negative Genetic, Negative Genetic
MOT1	YPL082C	Essential protein involved in regulation of transcription	physical	2	2	1	Affinity Capture-MS, Affinity Capture-Western
NAB3	YPL190C	RNA-binding protein, subunit of Nrd1 complex (Nrd1p-Nab3p-Sen1p)	genetic	2	2	1	Dosage Rescue, Phenotypic Enhancement
LYS21	YDL131W	Homocitrate synthase isozyme	genetic	2	2	1	Dosage Rescue, Phenotypic Suppression
TTI1	YKL033W	Subunit of the ASTRA complex, involved in chromatin remodeling	genetic	2	2	1	Negative Genetic, Positive Genetic
ETR1	YBR026C	2-enoyl thioester reductase	genetic	2	2	1	Positive Genetic, Negative Genetic
MKT1	YNL085W	Protein similar to nucleases that forms a complex with Pbp1p	genetic	2	2	1	Positive Genetic, Negative Genetic
YBR238C	YBR238C	Mitochondrial membrane protein	genetic	2	2	1	Positive Genetic, Negative Genetic
SSD1	YDR293C	Translational repressor	genetic	2	2	1	Positive Genetic, Negative Genetic
DAM1	YGR113W	Essential subunit of the Dam1 complex (aka DASH complex)	genetic	2	2	1	Positive Genetic, Negative Genetic
EOS1	YNL080C	Protein involved in N-glycosylation	genetic	2	2	1	Positive Genetic, Negative Genetic
CTF19	YPL018W	Outer kinetochore protein, needed for accurate chromosome segregation	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
MFT1	YML062C	Subunit of the THO complex	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
IES2	YNL215W	Protein that associates with the INO80 chromatin remodeling complex	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
WHI5	YOR083W	Repressor of G1 transcription	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
SSE1	YPL106C	ATPase component of heat shock protein Hsp90 chaperone complex	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
NEW1	YPL226W	Translation termination and ribosome biogenesis factor	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
HAC1	YFL031W	Basic leucine zipper (bZIP) transcription factor (ATF/CREB1 homolog)	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
PUB1	YNL016W	Poly (A)+ RNA-binding protein	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
GOS1	YHL031C	v-SNARE protein involved in Golgi transport	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
YKE2	YLR200W	Subunit of the heterohexameric Gim/prefoldin protein complex	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
SWI3	YJL176C	Subunit of the SWI/SNF chromatin remodeling complex	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
GCR2	YNL199C	Transcriptional activator of genes involved in glycolysis	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
VPS54	YDR027C	Component of the GARP (Golgi-associated retrograde protein) complex	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
GAS1	YMR307W	Beta-1,3-glucanosyltransferase required for cell wall assembly	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
MID1	YNL291C	Stretch-activated Ca2+-permeable cation channel	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
TOF1	YNL273W	Subunit of a replication-pausing checkpoint complex	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
RTS1	YOR014W	B-type regulatory subunit of protein phosphatase 2A (PP2A)	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
HIR2	YOR038C	Subunit of HIR nucleosome assembly complex	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
NBA1	YOL070C	Protein involved in axial bud site selection	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
SPP1	YPL138C	Subunit of COMPASS (Set1C)	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
RGD1	YBR260C	GTPase-activating protein (RhoGAP) for Rho3p and Rho4p	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
SNF11	YDR073W	Subunit of the SWI/SNF chromatin remodeling complex	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
RTT107	YHR154W	BRCA1 C-terminal domain protein needed for recovery from DNA damage	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
STB5	YHR178W	Transcription factor	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
SGF29	YCL010C	Component of the HAT/Core module of the SAGA, SLIK, and ADA complexes	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
KTI12	YKL110C	Protein that plays a role in modification of tRNA wobble nucleosides	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
RAD27	YKL113C	5' to 3' exonuclease, 5' flap endonuclease	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
LEO1	YOR123C	Component of the Paf1 complex	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
SLK19	YOR195W	Kinetochore-associated protein	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
LIP5	YOR196C	Protein involved in biosynthesis of the coenzyme lipoic acid	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
MMS22	YLR320W	Subunit of E3 ubiquitin ligase complex involved in replication repair	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
RPA14	YDR156W	RNA polymerase I subunit A14	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
SAC3	YDR159W	mRNA export factor	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
SLA1	YBL007C	Cytoskeletal protein binding protein	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
HIR1	YBL008W	Subunit of the HIR complex	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
MAD1	YGL086W	Coiled-coil protein involved in spindle-assembly checkpoint	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
PSD1	YNL169C	Phosphatidylserine decarboxylase of the mitochondrial inner membrane	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
MCM21	YDR318W	Component of the kinetochore sub-complex COMA	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
PAP2	YOL115W	Non-canonical poly(A) polymerase	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
RAD5	YLR032W	DNA helicase/Ubiquitin ligase	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
GIM5	YML094W	Subunit of the heterohexameric cochaperone prefoldin complex	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
SRS2	YJL092W	DNA helicase and DNA-dependent ATPase	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
MAD2	YJL030W	Component of the spindle-assembly checkpoint complex	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
RAD57	YDR004W	Protein that stimulates strand exchange	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
RAD18	YCR066W	E3 ubiquitin ligase	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
POL32	YJR043C	Third subunit of DNA polymerase delta	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
IWR1	YDL115C	RNA polymerase II transport factor, conserved from yeast to humans	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
POP2	YNR052C	Subunit of Ccr4-Not complex that mediates 3' to 5' mRNA deadenylation	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
PFA5	YDR459C	Palmitoyltransferase with autoacylation activity	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
RAD54	YGL163C	DNA-dependent ATPase that stimulates strand exchange	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
RIB4	YOL143C	Lumazine synthase (DMRL synthase)	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
NAT1	YDL040C	Subunit of protein N-terminal acetyltransferase NatA	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
RPL16B	YNL069C	Ribosomal 60S subunit protein L16B	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
HDA2	YDR295C	Subunit of HDA1 histone deacetylase complex	genetic	2	1	1	Synthetic Rescue, Synthetic Rescue
SIN3	YOL004W	Component of both the Rpd3S and Rpd3L histone deacetylase complexes	genetic	2	1	1	Synthetic Rescue, Synthetic Rescue
EST2	YLR318W	Reverse transcriptase subunit of the telomerase holoenzyme	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
FAR8	YMR029C	Protein involved in recovery from arrest in response to pheromone	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
FTR1	YER145C	High affinity iron permease	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
GCS1	YDL226C	ADP-ribosylation factor GTPase activating protein (ARF GAP)	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
GET1	YGL020C	Subunit of the GET complex	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
GET3	YDL100C	Guanine nucleotide exchange factor for Gpa1p	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
GGA2	YHR108W	Protein that regulates Arf1p, Arf2p to facilitate Golgi trafficking	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
GLO3	YER122C	ADP-ribosylation factor GTPase activating protein (ARF GAP)	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
GRR1	YJR090C	F-box protein component of an SCF ubiquitin-ligase complex	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
GRX1	YCL035C	Glutathione-dependent disulfide oxidoreductase	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
GUP1	YGL084C	Plasma membrane protein involved in remodeling GPI anchors	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
GYP1	YOR070C	Cis-golgi GTPase-activating protein (GAP) for yeast Rabs	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
HAL5	YJL165C	Snf1p-related nutrient-responsive protein kinase	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
HEK2	YBL032W	RNA binding protein involved in asymmetric localization of ASH1 mRNA	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
HFI1	YPL254W	Adaptor protein required for structural integrity of the SAGA complex	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
HIT1	YJR055W	Protein involved in C/D snoRNP assembly	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
HXK2	YGL253W	Hexokinase isoenzyme 2	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
INP51	YIL002C	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
IPP1	YBR011C	Cytoplasmic inorganic pyrophosphatase (PPase)	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
IRS4	YKR019C	EH domain-containing protein	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
ISW2	YOR304W	ATP-dependent DNA translocase involved in chromatin remodeling	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
KTR3	YBR205W	Putative alpha-1,2-mannosyltransferase	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
LDB7	YBL006C	Component of the RSC chromatin remodeling complex	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
LSM6	YDR378C	Lsm (Like Sm) protein	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
LTE1	YAL024C	Protein similar to GDP/GTP exchange factors	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
MAK10	YEL053C	Non-catalytic subunit of the NatC N-terminal acetyltransferase	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
MDM20	YOL076W	Non-catalytic subunit of the NatB N-terminal acetyltransferase	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
MED2	YDL005C	Subunit of the RNA polymerase II mediator complex	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
MET18	YIL128W	Component of cytosolic iron-sulfur protein assembly (CIA) machinery	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
MNN11	YJL183W	Subunit of a Golgi mannosyltransferase complex	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
MOD5	YOR274W	Delta 2-isopentenyl pyrophosphate:tRNA isopentenyl transferase	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
MOT2	YER068W	Ubiquitin-protein ligase subunit of the CCR4-NOT complex	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
MPC54	YOR177C	Component of the meiotic outer plaque	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
MRP51	YPL118W	Mitochondrial ribosomal protein of the small subunit	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
MRPL11	YDL202W	Mitochondrial ribosomal protein of the large subunit	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
MTF1	YMR228W	Mitochondrial RNA polymerase specificity factor	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
NAM7	YMR080C	ATP-dependent RNA helicase of the SFI superfamily	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
NGG1	YDR176W	Subunit of chromatin modifying histone acetyltransferase complexes	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
NHX1	YDR456W	Na+/H+ and K+/H+ exchanger	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
NKP2	YLR315W	Central kinetochore protein and subunit of the Ctf19 complex	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
NPL3	YDR432W	RNA-binding protein	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
NPR2	YEL062W	Subunit of the Iml1p/SEACIT complex	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
NRP1	YDL167C	Putative RNA binding protein of unknown function	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
NSG1	YHR133C	Protein involved in regulation of sterol biosynthesis	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
OAC1	YKL120W	Mitochondrial inner membrane transporter	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
OSH3	YHR073W	Member of an oxysterol-binding protein family	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
PEP3	YLR148W	Component of CORVET membrane tethering complex	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
PEP5	YMR231W	Histone E3 ligase, component of CORVET membrane tethering complex	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
PGS1	YCL004W	Phosphatidylglycerolphosphate synthase	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
SND3	YBR106W	Involved in SRP-independent protein targeting to the ER	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
PIM1	YBL022C	ATP-dependent Lon protease	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
PSD2	YGR170W	Phosphatidylserine decarboxylase of the Golgi and vacuolar membranes	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
RAD23	YEL037C	Protein with ubiquitin-like N terminus	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
RAV1	YJR033C	Subunit of RAVE complex (Rav1p, Rav2p, Skp1p)	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
RCY1	YJL204C	F-box protein involved in recycling endocytosed proteins	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
RER1	YCL001W	Protein involved in retention of membrane proteins	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
RGT1	YKL038W	Glucose-responsive transcription factor	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
RIC1	YLR039C	Protein involved in retrograde transport to the cis-Golgi network	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
RIM13	YMR154C	Calpain-like cysteine protease	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
RIM20	YOR275C	Protein involved in proteolytic activation of Rim101p	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
ROT2	YBR229C	Glucosidase II catalytic subunit	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
RPB9	YGL070C	RNA polymerase II subunit B12.6	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
RPN10	YHR200W	Proteasome polyubiquitin receptor	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
RPS19A	YOL121C	Protein component of the small (40S) ribosomal subunit	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
RSC1	YGR056W	Component of the RSC chromatin remodeling complex	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
RTG1	YOL067C	Transcription factor (bHLH) involved in interorganelle communication	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
RTG2	YGL252C	Sensor of mitochondrial dysfunction	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
RTT103	YDR289C	Protein involved in transcription termination by RNA polymerase II	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
RTT106	YNL206C	Histone chaperone	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
RVS161	YCR009C	Amphiphysin-like lipid raft protein	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
RVS167	YDR388W	Calmodulin-binding actin-associated protein	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
SAP155	YFR040W	Protein required for function of the Sit4p protein phosphatase	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
SAS5	YOR213C	Subunit of the SAS complex (Sas2p, Sas4p, Sas5p)	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
SAT4	YCR008W	Ser/Thr protein kinase involved in salt tolerance, nutrient response	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
SCJ1	YMR214W	One of several homologs of bacterial chaperone DnaJ	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
SEC66	YBR171W	Non-essential subunit of Sec63 complex	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
RKM4	YDR257C	Ribosomal lysine methyltransferase	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
SGO1	YOR073W	Component of the spindle checkpoint	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
SIC1	YLR079W	Cyclin-dependent kinase inhibitor (CKI)	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
SIR3	YLR442C	Silencing protein	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
SIR4	YDR227W	SIR protein involved in assembly of silent chromatin domains	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
SMI1	YGR229C	Protein involved in the regulation of cell wall synthesis	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
SNF2	YOR290C	Catalytic subunit of the SWI/SNF chromatin remodeling complex	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
SPF1	YEL031W	P-type ATPase, ion transporter of the ER membrane	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
SPS1	YDR523C	STE20-family GCKIII protein kinase	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
SPT20	YOL148C	Subunit of the SAGA transcriptional regulatory complex	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
SPT3	YDR392W	Subunit of the SAGA and SAGA-like transcriptional regulatory complexes	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
SPT4	YGR063C	Spt4p/5p (DSIF) transcription elongation factor complex subunit	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
SPT7	YBR081C	Subunit of the SAGA transcriptional regulatory complex	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
SRO7	YPR032W	Effector of Rab GTPase Sec4p	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
SRO9	YCL037C	Cytoplasmic RNA-binding protein	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
SSN2	YDR443C	Subunit of the RNA polymerase II mediator complex	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
SSN3	YPL042C	Component of the RNA polymerase II mediator complex	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
STP22	YCL008C	Component of the ESCRT-I complex	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
STV1	YMR054W	Subunit a of the vacuolar-ATPase V0 domain	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
SWC7	YLR385C	Protein of unknown function	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
SWM1	YDR260C	Subunit of the anaphase-promoting complex (APC)	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
SWS2	YNL081C	Putative mitochondrial ribosomal protein of the small subunit	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
TAF14	YPL129W	Subunit of TFIID, TFIIF, INO80, SWI/SNF, and NuA3 complexes	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
THR1	YHR025W	Homoserine kinase	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
TMA16	YOR252W	Protein of unknown function that associates with ribosomes	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
TOM1	YDR457W	E3 ubiquitin ligase of the hect-domain class	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
TRK1	YJL129C	Component of the Trk1p-Trk2p potassium transport system	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
TVP18	YMR071C	Integral membrane protein	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
UBP14	YBR058C	Ubiquitin-specific protease	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
UBP2	YOR124C	Ubiquitin-specific protease	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
UFD1	YGR048W	Substrate-recruiting cofactor of the Cdc48p-Npl4p-Ufd1p segregase	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
URE2	YNL229C	Nitrogen catabolite repression transcriptional regulator	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
URM1	YIL008W	Ubiquitin-like protein involved in thiolation of cytoplasmic tRNAs	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
VAM10	YOR068C	Protein involved in vacuole morphogenesis	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
VID22	YLR373C	G-quadruplex (G4) DNA binding protein	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
VMA4	YOR332W	Subunit E of the V1 domain of the vacuolar H+-ATPase (V-ATPase)	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
VMA5	YKL080W	Subunit C of the V1 peripheral membrane domain of V-ATPase	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
VPH1	YOR270C	Subunit a of the vacuolar-ATPase V0 domain	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
VPS16	YPL045W	Subunit of the HOPS and the CORVET complexes	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
VPS17	YOR132W	Subunit of the membrane-associated retromer complex	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
VPS21	YOR089C	Endosomal Rab family GTPase	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
VPS25	YJR102C	Component of the ESCRT-II complex	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
VPS29	YHR012W	Subunit of the membrane-associated retromer complex	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
VPS3	YDR495C	Component of CORVET membrane tethering complex	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
VPS30	YPL120W	Subunit of phosphatidylinositol (PtdIns) 3-kinase complexes I and II	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
VPS33	YLR396C	ATP-binding protein that is a subunit of the HOPS and CORVET complexes	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
VPS35	YJL154C	Endosomal subunit of membrane-associated retromer complex	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
VPS36	YLR417W	Component of the ESCRT-II complex	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
VPS38	YLR360W	Part of a Vps34p phosphatidylinositol 3-kinase complex	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
VPS45	YGL095C	Protein of the Sec1p/Munc-18 family	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
VPS5	YOR069W	Nexin-1 homolog	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
VPS52	YDR484W	Component of the GARP (Golgi-associated retrograde protein) complex	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
VPS60	YDR486C	Protein involved in late endosome to vacuole transport	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
VPS68	YOL129W	Vacuolar membrane protein of unknown function	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
VPS71	YML041C	Nucleosome-binding component of the SWR1 complex	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
VTA1	YLR181C	Multivesicular body (MVB) protein	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
YNG1	YOR064C	Subunit of the NuA3 histone acetyltransferase complex	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
YPT52	YKR014C	Endosomal Rab family GTPase	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
YTA12	YMR089C	Mitochondrial inner membrane m-AAA protease component	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
ORC2	YBR060C	Subunit of the origin recognition complex (ORC)	genetic	2	1	1	Negative Genetic, Negative Genetic
POP7	YBR167C	Subunit of RNase MRP, nuclear RNase P and telomerase	genetic	2	1	1	Negative Genetic, Negative Genetic
TRS20	YBR254C	Core component of transport protein particle (TRAPP) complexes I-III	genetic	2	1	1	Negative Genetic, Negative Genetic
NSE4	YDL105W	Component of the SMC5-SMC6 complex	genetic	2	1	1	Negative Genetic, Negative Genetic
TIM22	YDL217C	Essential core component of mitochondrial TIM22 complex	genetic	2	1	1	Negative Genetic, Negative Genetic
PSF1	YDR013W	Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p)	genetic	2	1	1	Negative Genetic, Negative Genetic
NSE3	YDR288W	Component of the SMC5-SMC6 complex	genetic	2	1	1	Negative Genetic, Negative Genetic
YCG1	YDR325W	Subunit of the condensin complex	genetic	2	1	1	Negative Genetic, Negative Genetic
GPI8	YDR331W	Catalytic subunit of the ER membrane GPI transamidase complex	genetic	2	1	1	Negative Genetic, Negative Genetic
FRQ1	YDR373W	N-myristoylated calcium-binding protein	genetic	2	1	1	Negative Genetic, Negative Genetic
SLD5	YDR489W	Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p)	genetic	2	1	1	Negative Genetic, Negative Genetic
PSF2	YJL072C	Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p)	genetic	2	1	1	Negative Genetic, Negative Genetic
EXO70	YJL085W	Subunit of the exocyst complex	genetic	2	1	1	Negative Genetic, Negative Genetic
FIP1	YJR093C	Subunit of cleavage polyadenylation factor (CPF)	genetic	2	1	1	Negative Genetic, Negative Genetic
ORC3	YLL004W	Subunit of the origin recognition complex (ORC)	genetic	2	1	1	Negative Genetic, Negative Genetic
NSE1	YLR007W	Component of the SMC5-SMC6 complex	genetic	2	1	1	Negative Genetic, Negative Genetic
PRP24	YMR268C	Splicing factor that reanneals snRNPs during spliceosome recycling	genetic	2	1	1	Negative Genetic, Negative Genetic
TFC8	YPL007C	Subunit of RNA polymerase III transcription initiation factor complex	genetic	2	1	1	Negative Genetic, Negative Genetic
ULP1	YPL020C	Protease that specifically cleaves Smt3p protein conjugates	genetic	2	1	1	Negative Genetic, Negative Genetic
TIF6	YPR016C	Constituent of 66S pre-ribosomal particles	genetic	2	1	1	Negative Genetic, Negative Genetic
ARL1	YBR164C	Soluble GTPase with a role in regulation of membrane traffic	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
AAH1	YNL141W	Adenine deaminase (adenine aminohydrolase)	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
CCR4	YAL021C	Component of the CCR4-NOT transcriptional complex	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
APC1	YNL172W	Largest subunit of the Anaphase-Promoting Complex/Cyclosome	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
APC2	YLR127C	Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C)	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
APL6	YGR261C	Beta3-like subunit of the yeast AP-3 complex	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
ARD1	YHR013C	Subunit of protein N-terminal acetyltransferase NatA	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
BUD14	YAR014C	Protein involved in bud-site selection	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
CAF130	YGR134W	Subunit of the CCR4-NOT transcriptional regulatory complex	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
CAF40	YNL288W	Component of the CCR4-NOT transcriptional complex	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
CDC24	YAL041W	Guanine nucleotide exchange factor (GEF) for Cdc42p	genetic	2	1	1	Negative Genetic, Negative Genetic
ATP11	YNL315C	Molecular chaperone	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
CTF18	YMR078C	Subunit of a complex with Ctf8p	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
DNA2	YHR164C	ATP-dependent 5'-flap endonuclease and DNA helicase	genetic	2	1	1	Negative Genetic, Negative Genetic
DOA1	YKL213C	WD-repeat protein involved in ubiquitin-mediated protein degradation	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
ELP2	YGR200C	Subunit of Elongator complex	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
BDF2	YDL070W	Protein involved in transcription initiation	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
DHH1	YDL160C	Cytoplasmic DEAD-box helicase and mRNA decapping activator	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
DPB4	YDR121W	Subunit of DNA pol epsilon and of ISW2 chromatin accessibility complex	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
COG8	YML071C	Component of the conserved oligomeric Golgi complex	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
ECM29	YHL030W	Scaffold protein	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
END3	YNL084C	EH domain-containing protein involved in endocytosis	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
COG3	YER157W	Essential component of the conserved oligomeric Golgi complex	genetic	2	1	1	Negative Genetic, Negative Genetic
APM1	YPL259C	Mu1-like medium subunit of the AP-1 complex	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
CDC13	YDL220C	Single stranded DNA-binding protein found at TG1-3 telomere G-tails	genetic	2	1	1	Negative Genetic, Negative Genetic
ATG17	YLR423C	Scaffold protein responsible for phagophore assembly site organization	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
BUB2	YMR055C	Mitotic exit network regulator	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
CNB1	YKL190W	Calcineurin B	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
ACS2	YLR153C	Acetyl-coA synthetase isoform	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
DPB11	YJL090C	DNA replication initiation protein	genetic	2	1	1	Negative Genetic, Negative Genetic
BEM4	YPL161C	Protein involved in establishment of cell polarity and bud emergence	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
CTR1	YPR124W	High-affinity copper transporter of plasma membrane	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
APE3	YBR286W	Vacuolar aminopeptidase Y	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
CDH1	YGL003C	Activator of anaphase-promoting complex/cyclosome (APC/C)	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
APL4	YPR029C	Gamma-adaptin	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
CTK3	YML112W	Gamma subunit of C-terminal domain kinase I	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
CUE5	YOR042W	Ubiquitin-binding protein	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
BIM1	YER016W	Microtubule plus end-tracking protein	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
AFT1	YGL071W	Transcription factor involved in iron utilization and homeostasis	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
APC9	YLR102C	Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C)	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
COG7	YGL005C	Component of the conserved oligomeric Golgi complex	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
ELP4	YPL101W	Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
DOC1	YGL240W	Processivity factor	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
DAL81	YIR023W	Positive regulator of genes in multiple nitrogen degradation pathways	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
BRN1	YBL097W	Subunit of the condensin complex	genetic	2	1	1	Negative Genetic, Negative Genetic
CTF8	YHR191C	Subunit of a complex with Ctf18p	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
CTK2	YJL006C	Beta subunit of C-terminal domain kinase I (CTDK-I)	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
ELO3	YLR372W	Elongase	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
BIK1	YCL029C	Microtubule-associated protein	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
CCZ1	YBR131W	Subunit of a heterodimeric guanine nucleotide exchange factor (GEF)	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
CHS5	YLR330W	Component of the exomer complex	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
COY1	YKL179C	Golgi membrane protein with similarity to mammalian CASP	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
CUE4	YML101C	Protein of unknown function	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
ERG2	YMR202W	C-8 sterol isomerase	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
ATP14	YLR295C	Subunit h of the F0 sector of mitochondrial F1F0 ATP synthase	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
CUE1	YMR264W	Ubiquitin-binding protein	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
DCC1	YCL016C	Subunit of a complex with Ctf8p and Ctf18p	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
CYK3	YDL117W	SH3-domain protein located in the bud neck and cytokinetic actin ring	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
CUP9	YPL177C	Homeodomain-containing transcriptional repressor	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
DEG1	YFL001W	tRNA:pseudouridine synthase	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
DIA1	YMR316W	Protein of unknown function	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
ECM7	YLR443W	Putative integral membrane protein with a role in calcium uptake	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
ERG24	YNL280C	C-14 sterol reductase	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
CDC50	YCR094W	Endosomal protein that interacts with phospholipid flippase Drs2p	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
DCR2	YLR361C	Protein phosphatase	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
EFG1	YGR271C-A	Ribosome biogenesis factor required for maturation of 18S rRNA	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
DCW1	YKL046C	Putative mannosidase	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
DIE2	YGR227W	Dolichyl-phosphoglucose-dependent alpha-1,2-glucosyltransferase	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
APS3	YJL024C	Small subunit of the clathrin-associated adaptor complex AP-3	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
ALG8	YOR067C	Glucosyl transferase	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
ECM14	YHR132C	Conserved fungal protein with similarity to zinc carboxypeptidases	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
ARG2	YJL071W	Acetylglutamate synthase (glutamate N-acetyltransferase)	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
CDA2	YLR308W	Chitin deacetylase	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
SFP1	YLR403W	Regulates transcription of ribosomal protein and biogenesis genes	regulation	1	1	1	DNA to cDNA expression microarray evidence
XBP1	YIL101C	Transcriptional repressor	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
PIF1	YML061C	DNA helicase, potent G-quadruplex DNA binder/unwinder	regulation	1	1	1	qualitative western immunoblotting evidence
INM1	YHR046C	Inositol monophosphatase	regulation	1	1	1	chromatin immunoprecipitation-qPCR evidence
AME1	YBR211C	Essential kinetochore protein associated with microtubules and SPBs	genetic	1	1	1	Negative Genetic
SAP185	YJL098W	Protein that forms a complex with the Sit4p protein phosphatase	physical	1	1	1	Affinity Capture-MS
HTZ1	YOL012C	Histone variant H2AZ	physical	1	1	1	Biochemical Activity
PDX3	YBR035C	Pyridoxine (pyridoxamine) phosphate oxidase	physical	1	1	1	Biochemical Activity
YSW1	YBR148W	Protein required for normal prospore membrane formation	physical	1	1	1	Biochemical Activity
GLK1	YCL040W	Glucokinase	physical	1	1	1	Biochemical Activity
SPB1	YCL054W	AdoMet-dependent methyltransferase	physical	1	1	1	Biochemical Activity
SKP1	YDR328C	Evolutionarily conserved kinetochore protein	physical	1	1	1	Biochemical Activity
SVF1	YDR346C	Protein with a potential role in cell survival pathways	physical	1	1	1	Biochemical Activity
PRO3	YER023W	Delta 1-pyrroline-5-carboxylate reductase	physical	1	1	1	Biochemical Activity
YER134C	YER134C	Magnesium-dependent acid phosphatase	physical	1	1	1	Biochemical Activity
GRX4	YER174C	Glutathione-dependent oxidoreductase and glutathione S-transferase	physical	1	1	1	Biochemical Activity
LSG1	YGL099W	Putative GTPase involved in 60S ribosomal subunit biogenesis	physical	1	1	1	Biochemical Activity
SPT16	YGL207W	Subunit of the heterodimeric FACT complex (Spt16p-Pob3p)	physical	1	1	1	Biochemical Activity
SIP2	YGL208W	One of three alternate beta subunits of the Snf1 kinase complex	physical	1	1	1	Biochemical Activity
SIP2	YGL208W	One of three alternate beta subunits of the Snf1 kinase complex	genetic	1	1	1	Synthetic Rescue
SKI8	YGL213C	Ski complex component and WD-repeat protein	physical	1	1	1	Biochemical Activity
YGR017W	YGR017W	Putative protein of unknown function	physical	1	1	1	Biochemical Activity
VOA1	YGR106C	ER protein that functions in assembly of the V0 sector of V-ATPase	physical	1	1	1	Biochemical Activity
RNR4	YGR180C	Ribonucleotide-diphosphate reductase (RNR) small subunit	physical	1	1	1	Biochemical Activity
OTU2	YHL013C	Protein of unknown function	physical	1	1	1	Biochemical Activity
YLF2	YHL014C	Protein of unknown function	physical	1	1	1	Biochemical Activity
RPL8A	YHL033C	Ribosomal 60S subunit protein L8A	physical	1	1	1	Biochemical Activity
THS1	YIL078W	Threonyl-tRNA synthetase	physical	1	1	1	Biochemical Activity
IMP21	YIL154C	Transcriptional activator involved in maintenance of ion homeostasis	physical	1	1	1	Biochemical Activity
PRS1	YKL181W	5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase	physical	1	1	1	Biochemical Activity
NAP1	YKR048C	Histone chaperone and assembly chaperone for Rps6a/b	physical	1	1	1	Biochemical Activity
HBS1	YKR084C	GTPase with similarity to translation release factors	physical	1	1	1	Biochemical Activity
PCK1	YKR097W	Phosphoenolpyruvate carboxykinase	physical	1	1	1	Biochemical Activity
HIF1	YLL022C	Non-essential component of the HAT-B histone acetyltransferase complex	physical	1	1	1	Biochemical Activity
HSP104	YLL026W	Disaggregase	physical	1	1	1	Biochemical Activity
PRP19	YLL036C	Splicing factor associated with the spliceosome	physical	1	1	1	Biochemical Activity
HCR1	YLR192C	eIF3j component of translation initiation factor 3 (eIF3)	physical	1	1	1	Biochemical Activity
HCR1	YLR192C	eIF3j component of translation initiation factor 3 (eIF3)	genetic	1	1	1	Positive Genetic
NMT1	YLR195C	N-myristoyl transferase	physical	1	1	1	Biochemical Activity
YLR257W	YLR257W	Protein of unknown function	physical	1	1	1	Biochemical Activity
GSY2	YLR258W	Glycogen synthase	physical	1	1	1	Biochemical Activity
NEJ1	YLR265C	DNA end-binding protein required for nonhomologous end joining (NHEJ)	physical	1	1	1	Biochemical Activity
NNT1	YLR285W	S-adenosylmethionine-dependent methyltransferase	physical	1	1	1	Biochemical Activity
YLR345W	YLR345W	Similar to 6-phosphofructo-2-kinase enzymes	physical	1	1	1	Biochemical Activity
MFT1	YML062C	Subunit of the THO complex	physical	1	1	1	Biochemical Activity
FPR3	YML074C	Nucleolar peptidyl-prolyl cis-trans isomerase (PPIase)	physical	1	1	1	Biochemical Activity
UTP14	YML093W	Subunit of U3-containing Small Subunit (SSU) processome complex	physical	1	1	1	Biochemical Activity
TAP42	YMR028W	Essential protein involved in the TOR signaling pathway	physical	1	1	1	Biochemical Activity
SIP5	YMR140W	Protein of unknown function	physical	1	1	1	Biochemical Activity
YMR196W	YMR196W	Putative protein of unknown function	physical	1	1	1	Biochemical Activity
UBP15	YMR304W	Ubiquitin-specific protease involved in protein deubiquitination	physical	1	1	1	Biochemical Activity
IES2	YNL215W	Protein that associates with the INO80 chromatin remodeling complex	physical	1	1	1	Biochemical Activity
VPS75	YNL246W	NAP family histone chaperone	physical	1	1	1	Biochemical Activity
KRI1	YNL308C	Essential nucleolar protein required for 40S ribosome biogenesis	physical	1	1	1	Biochemical Activity
SOL1	YNR034W	Protein with a possible role in tRNA export	physical	1	1	1	Biochemical Activity
WHI5	YOR083W	Repressor of G1 transcription	physical	1	1	1	Biochemical Activity
RPT5	YOR117W	ATPase of the 19S regulatory particle of the 26S proteasome	physical	1	1	1	Biochemical Activity
PLP2	YOR281C	Protein that interacts with the CCT complex to stimulate actin folding	physical	1	1	1	Biochemical Activity
MSC6	YOR354C	Multicopy suppressor of HER2 involved in mitochondrial translation	physical	1	1	1	Biochemical Activity
LSP1	YPL004C	Eisosome core component	physical	1	1	1	Biochemical Activity
SSE1	YPL106C	ATPase component of heat shock protein Hsp90 chaperone complex	physical	1	1	1	Biochemical Activity
GDE1	YPL110C	Glycerophosphocholine (GroPCho) phosphodiesterase	physical	1	1	1	Biochemical Activity
UME1	YPL139C	Component of both the Rpd3S and Rpd3L histone deacetylase complexes	physical	1	1	1	Biochemical Activity
NAB3	YPL190C	RNA-binding protein, subunit of Nrd1 complex (Nrd1p-Nab3p-Sen1p)	physical	1	1	1	Biochemical Activity
FMP40	YPL222W	Mitochondrial AMPylator in the pseudokinase selenoprotein-O family	physical	1	1	1	Biochemical Activity
MDM36	YPR083W	Mitochondrial protein	physical	1	1	1	Biochemical Activity
YPR089W	YPR089W	Protein of unknown function	physical	1	1	1	Biochemical Activity
URN1	YPR152C	Protein of unknown function containing WW and FF domains	physical	1	1	1	Biochemical Activity
GPH1	YPR160W	Glycogen phosphorylase required for the mobilization of glycogen	physical	1	1	1	Biochemical Activity
GPH1	YPR160W	Glycogen phosphorylase required for the mobilization of glycogen	genetic	1	1	1	Negative Genetic
MET16	YPR167C	3'-phosphoadenylsulfate reductase	physical	1	1	1	Biochemical Activity
NAB2	YGL122C	Nuclear polyadenylated RNA-binding protein	physical	1	1	1	Affinity Capture-RNA
TAF12	YDR145W	Subunit (61/68 kDa) of TFIID and SAGA complexes	physical	1	1	1	Affinity Capture-Western
SHS1	YDL225W	Component of the septin ring that is required for cytokinesis	physical	1	1	1	Biochemical Activity
ESA1	YOR244W	Catalytic subunit of the histone acetyltransferase complex (NuA4)	physical	1	1	1	Affinity Capture-MS
PAB1	YER165W	Poly(A) binding protein	physical	1	1	1	Affinity Capture-MS
PBP1	YGR178C	Component of glucose deprivation induced stress granules	physical	1	1	1	Affinity Capture-MS
GDS1	YOR355W	Protein involved in histone H4 acetylation at ribosomal protein genes	physical	1	1	1	Affinity Capture-MS
HTB2	YBL002W	Histone H2B	physical	1	1	1	Affinity Capture-MS
KAP123	YER110C	Karyopherin beta	physical	1	1	1	Affinity Capture-MS
OLA1	YBR025C	P-loop ATPase with similarity to human OLA1 and bacterial YchF	physical	1	1	1	Affinity Capture-MS
RPS12	YOR369C	Protein component of the small (40S) ribosomal subunit	physical	1	1	1	Affinity Capture-MS
SSB1	YDL229W	Cytoplasmic ATPase that is a ribosome-associated molecular chaperone	physical	1	1	1	Affinity Capture-MS
FKS1	YLR342W	Catalytic subunit of 1,3-beta-D-glucan synthase	physical	1	1	1	Affinity Capture-MS
GCD11	YER025W	Gamma subunit of the translation initiation factor eIF2	physical	1	1	1	Affinity Capture-MS
NEW1	YPL226W	Translation termination and ribosome biogenesis factor	physical	1	1	1	Affinity Capture-MS
NUD1	YOR373W	Mitotic exit network (MEN) scaffold protein	physical	1	1	1	Affinity Capture-MS
SAR1	YPL218W	ARF family GTPase	physical	1	1	1	Affinity Capture-MS
SEC26	YDR238C	Essential beta-coat protein of the COPI coatomer	physical	1	1	1	Affinity Capture-MS
SEC27	YGL137W	Essential beta'-coat protein of the COPI coatomer	physical	1	1	1	Affinity Capture-MS
SKG6	YHR149C	Integral membrane protein	physical	1	1	1	Affinity Capture-MS
SPC110	YDR356W	Inner plaque spindle pole body (SPB) component	physical	1	1	1	Affinity Capture-MS
SPC42	YKL042W	Central plaque component of spindle pole body (SPB)	physical	1	1	1	Affinity Capture-MS
SPT6	YGR116W	Nucleosome remodeling protein	physical	1	1	1	Affinity Capture-MS
GCN1	YGL195W	Positive regulator of the Gcn2p kinase activity	physical	1	1	1	Affinity Capture-MS
GUS1	YGL245W	Glutamyl-tRNA synthetase (GluRS)	physical	1	1	1	Affinity Capture-MS
HCA4	YJL033W	DEAD box RNA helicase	physical	1	1	1	Affinity Capture-MS
HEF3	YNL014W	Translational elongation factor EF-3	physical	1	1	1	Affinity Capture-MS
LSM1	YJL124C	Lsm (Like Sm) protein	physical	1	1	1	Affinity Capture-MS
LSM12	YHR121W	Protein of unknown function that may function in RNA processing	physical	1	1	1	Affinity Capture-MS
MDM38	YOL027C	Membrane-associated mitochondrial ribosome receptor	physical	1	1	1	Affinity Capture-MS
MIR1	YJR077C	Mitochondrial phosphate carrier	physical	1	1	1	Affinity Capture-MS
RPL31A	YDL075W	Ribosomal 60S subunit protein L31A	physical	1	1	1	Affinity Capture-MS
RSC8	YFR037C	Component of the RSC chromatin remodeling complex	physical	1	1	1	Affinity Capture-MS
SAC6	YDR129C	Fimbrin, actin-bundling protein	physical	1	1	1	Affinity Capture-MS
SAS10	YDL153C	Subunit of U3-containing Small Subunit (SSU) processome complex	physical	1	1	1	Affinity Capture-MS
SAS10	YDL153C	Subunit of U3-containing Small Subunit (SSU) processome complex	genetic	1	1	1	Negative Genetic
SEC21	YNL287W	Gamma subunit of coatomer	physical	1	1	1	Affinity Capture-MS
SRP1	YNL189W	Karyopherin alpha homolog	physical	1	1	1	Affinity Capture-MS
STH1	YIL126W	ATPase component of the RSC chromatin remodeling complex	physical	1	1	1	Affinity Capture-MS
STM1	YLR150W	Protein required for optimal translation under nutrient stress	physical	1	1	1	Affinity Capture-MS
SXM1	YDR395W	Nuclear transport factor (karyopherin)	physical	1	1	1	Affinity Capture-MS
TCP1	YDR212W	Alpha subunit of chaperonin-containing T-complex	physical	1	1	1	Affinity Capture-MS
TIF3	YPR163C	Translation initiation factor eIF-4B	physical	1	1	1	Affinity Capture-MS
TUB1	YML085C	Alpha-tubulin	physical	1	1	1	Affinity Capture-MS
TUB2	YFL037W	Beta-tubulin	physical	1	1	1	Affinity Capture-MS
NPL6	YMR091C	Component of the RSC chromatin remodeling complex	physical	1	1	1	Affinity Capture-MS
PRE10	YOR362C	Alpha 7 subunit of the 20S proteasome	physical	1	1	1	Affinity Capture-MS
PRE6	YOL038W	Alpha 4 subunit of the 20S proteasome	physical	1	1	1	Affinity Capture-MS
RPN1	YHR027C	Non-ATPase base subunit of the 19S RP of the 26S proteasome	physical	1	1	1	Affinity Capture-MS
RPN11	YFR004W	Metalloprotease subunit of 19S regulatory particle	physical	1	1	1	Affinity Capture-MS
RPN3	YER021W	Essential non-ATPase regulatory subunit of the 26S proteasome lid	physical	1	1	1	Affinity Capture-MS
RPT1	YKL145W	ATPase of the 19S regulatory particle of the 26S proteasome	physical	1	1	1	Affinity Capture-MS
PBP4	YDL053C	Pbp1p binding protein	physical	1	1	1	Affinity Capture-MS
NOP4	YPL043W	Nucleolar protein	physical	1	1	1	Affinity Capture-MS
SPC29	YPL124W	Inner plaque spindle pole body (SPB) component	physical	1	1	1	Affinity Capture-MS
SPC29	YPL124W	Inner plaque spindle pole body (SPB) component	genetic	1	1	1	Negative Genetic
HAA1	YPR008W	Transcriptional activator involved in adaptation to weak acid stress	physical	1	1	1	Affinity Capture-MS
HAC1	YFL031W	Basic leucine zipper (bZIP) transcription factor (ATF/CREB1 homolog)	physical	1	1	1	Affinity Capture-MS
HOG1	YLR113W	Mitogen-activated protein kinase involved in osmoregulation	physical	1	1	1	Affinity Capture-MS
MSN2	YMR037C	Stress-responsive transcriptional activator	physical	1	1	1	Affinity Capture-MS
RPN4	YDL020C	Transcription factor that stimulates expression of proteasome genes	physical	1	1	1	Affinity Capture-MS
SPT5	YML010W	Spt4p/5p (DSIF) transcription elongation factor complex subunit	physical	1	1	1	Affinity Capture-MS
KAP95	YLR347C	Karyopherin beta	physical	1	1	1	Affinity Capture-MS
SEC13	YLR208W	Structural component of 3 complexes	physical	1	1	1	Affinity Capture-MS
SEC13	YLR208W	Structural component of 3 complexes	genetic	1	1	1	Negative Genetic
SEC24	YIL109C	Component of the Sec23p-Sec24p heterodimer of the COPII vesicle coat	physical	1	1	1	Affinity Capture-MS
SEC28	YIL076W	Epsilon-COP subunit of the coatomer	physical	1	1	1	Affinity Capture-MS
SEC7	YDR170C	Guanine nucleotide exchange factor (GEF) for ADP ribosylation factors	physical	1	1	1	Affinity Capture-MS
PUF3	YLL013C	Protein of the mitochondrial outer surface	physical	1	1	1	Affinity Capture-RNA
PUB1	YNL016W	Poly (A)+ RNA-binding protein	physical	1	1	1	Affinity Capture-MS
PIF1	YML061C	DNA helicase, potent G-quadruplex DNA binder/unwinder	physical	1	1	1	Biochemical Activity
MLH3	YPL164C	Protein involved in DNA mismatch repair and meiotic recombination	physical	1	1	1	Affinity Capture-MS
SLD3	YGL113W	Protein involved in the initiation of DNA replication	physical	1	1	1	Two-hybrid
SLD3	YGL113W	Protein involved in the initiation of DNA replication	genetic	1	1	1	Negative Genetic
SLD7	YOR060C	Protein with a role in chromosomal DNA replication	physical	1	1	1	Two-hybrid
HSL7	YBR133C	Protein arginine N-methyltransferase	genetic	1	1	1	Synthetic Growth Defect
ZNF1	YFL052W	Zinc cluster transcription factor that regulates respiratory growth	genetic	1	1	1	Negative Genetic
NUT1	YGL151W	Component of the RNA polymerase II mediator complex	genetic	1	1	1	Negative Genetic
IRE1	YHR079C	Serine-threonine kinase and endoribonuclease	genetic	1	1	1	Negative Genetic
SNX4	YJL036W	Sorting nexin	genetic	1	1	1	Negative Genetic
YLL058W	YLL058W	Putative protein of unknown function with similarity to Str2p	genetic	1	1	1	Negative Genetic
POM34	YLR018C	Subunit of the transmembrane ring of the nuclear pore complex (NPC)	genetic	1	1	1	Negative Genetic
PAU23	YLR037C	Cell wall mannoprotein	genetic	1	1	1	Negative Genetic
YLR046C	YLR046C	Putative membrane protein	genetic	1	1	1	Negative Genetic
SRL2	YLR082C	Protein of unknown function	genetic	1	1	1	Negative Genetic
GIS3	YLR094C	Protein of unknown function	genetic	1	1	1	Negative Genetic
LCL2	YLR104W	Putative protein of unknown function	genetic	1	1	1	Negative Genetic
TIS11	YLR136C	mRNA-binding protein expressed during iron starvation	genetic	1	1	1	Negative Genetic
RKM5	YLR137W	Protein lysine methyltransferase	genetic	1	1	1	Negative Genetic
TAG1	YLR173W	Vacuolar membrane protein involved in termination of autophagy	genetic	1	1	1	Negative Genetic
LIP2	YLR239C	Lipoyl ligase	genetic	1	1	1	Positive Genetic
YLR278C	YLR278C	Zinc-cluster protein	genetic	1	1	1	Negative Genetic
RPS30A	YLR287C-A	Protein component of the small (40S) ribosomal subunit	genetic	1	1	1	Positive Genetic
VRP1	YLR337C	Verprolin, proline-rich actin-associated protein	genetic	1	1	1	Positive Genetic
RPL26A	YLR344W	Ribosomal 60S subunit protein L26A	genetic	1	1	1	Negative Genetic
PSY3	YLR376C	Component of Shu complex (aka PCSS complex)	genetic	1	1	1	Negative Genetic
FUS2	YMR232W	Cell fusion regulator	genetic	1	1	1	Negative Genetic
YMR244W	YMR244W	Putative protein of unknown function	genetic	1	1	1	Positive Genetic
LSM7	YNL147W	Lsm (Like Sm) protein	genetic	1	1	1	Negative Genetic
TAT1	YBR069C	Amino acid transporter for valine, leucine, isoleucine, and tyrosine	genetic	1	1	1	Dosage Rescue
LEU2	YCL018W	Beta-isopropylmalate dehydrogenase (IMDH)	genetic	1	1	1	Dosage Rescue
TBF1	YPL128C	Telobox-containing general regulatory factor	genetic	1	1	1	Synthetic Growth Defect
SMC3	YJL074C	Subunit of the multiprotein cohesin complex	genetic	1	1	1	Synthetic Lethality
TEL2	YGR099W	Subunit of the ASTRA complex, involved in chromatin remodeling	genetic	1	1	1	Negative Genetic
TTI2	YJR136C	Subunit of the ASTRA complex, involved in chromatin remodeling	genetic	1	1	1	Negative Genetic
MMS2	YGL087C	Ubiquitin-conjugating enzyme variant	genetic	1	1	1	Synthetic Growth Defect
REV3	YPL167C	Catalytic subunit of DNA polymerase zeta	genetic	1	1	1	Synthetic Growth Defect
HST2	YPL015C	Cytoplasmic NAD(+)-dependent protein deacetylase	genetic	1	1	1	Phenotypic Suppression
PKC1	YBL105C	Protein serine/threonine kinase	genetic	1	1	1	Positive Genetic
PWP2	YCR057C	Conserved 90S pre-ribosomal component	genetic	1	1	1	Positive Genetic
RPL10	YLR075W	Ribosomal 60S subunit protein L10	genetic	1	1	1	Positive Genetic
MAK21	YDR060W	Constituent of 66S pre-ribosomal particles	genetic	1	1	1	Positive Genetic
RSP5	YER125W	NEDD4 family E3 ubiquitin ligase	genetic	1	1	1	Positive Genetic
GPI19	YDR437W	Subunit of GPI-GlcNAc transferase involved in synthesis of GlcNAc-PI	genetic	1	1	1	Positive Genetic
RNA1	YMR235C	GTPase activating protein (GAP) for Gsp1p	genetic	1	1	1	Positive Genetic
RPA34	YJL148W	RNA polymerase I subunit A34.5	genetic	1	1	1	Positive Genetic
KCH1	YJR054W	Potassium transporter that mediates K+ influx	genetic	1	1	1	Positive Genetic
YRA2	YKL214C	Member of the REF (RNA and export factor binding proteins) family	genetic	1	1	1	Positive Genetic
IMP2	YMR035W	Catalytic subunit of mitochondrial inner membrane peptidase complex	genetic	1	1	1	Positive Genetic
TBS1	YBR150C	Protein of unknown function	genetic	1	1	1	Positive Genetic
GPR1	YDL035C	Plasma membrane G protein coupled receptor (GPCR)	genetic	1	1	1	Positive Genetic
PEX19	YDL065C	Chaperone and import receptor for newly-synthesized class I PMPs	genetic	1	1	1	Positive Genetic
NDE2	YDL085W	Mitochondrial external NADH dehydrogenase	genetic	1	1	1	Positive Genetic
MRPL1	YDR116C	Mitochondrial ribosomal protein of the large subunit	genetic	1	1	1	Positive Genetic
YGL036W	YGL036W	Putative protein of unknown function	genetic	1	1	1	Positive Genetic
ITC1	YGL133W	Subunit of ATP-dependent Isw2p-Itc1p chromatin remodeling complex	genetic	1	1	1	Positive Genetic
SPO74	YGL170C	Component of the meiotic outer plaque of the spindle pole body	genetic	1	1	1	Positive Genetic
SRB2	YHR041C	Subunit of the RNA polymerase II mediator complex	genetic	1	1	1	Positive Genetic
YIA6	YIL006W	Mitochondrial NAD+ transporter	genetic	1	1	1	Positive Genetic
PIR5	YJL160C	Putative protein of unknown function	genetic	1	1	1	Positive Genetic
YJR084W	YJR084W	Protein that forms a complex with Thp3p	genetic	1	1	1	Positive Genetic
MMO1	YKL044W	Protein of unknown function	genetic	1	1	1	Positive Genetic
YKR015C	YKR015C	Putative protein of unknown function	genetic	1	1	1	Positive Genetic
RPS21A	YKR057W	Protein component of the small (40S) ribosomal subunit	genetic	1	1	1	Positive Genetic
RPL8B	YLL045C	Ribosomal 60S subunit protein L8A	genetic	1	1	1	Positive Genetic
YLR053C	YLR053C	Putative protein of unknown function	genetic	1	1	1	Positive Genetic
SND2	YLR065C	Protein involved in SRP-independent targeting of substrates to the ER	genetic	1	1	1	Positive Genetic
HMX1	YLR205C	ER localized heme oxygenase	genetic	1	1	1	Positive Genetic
PEX9	YMR018W	Peroxisomal membrane signal receptor for peroxisomal matrix proteins	genetic	1	1	1	Positive Genetic
GLC8	YMR311C	Regulatory subunit of protein phosphatase 1 (Glc7p)	genetic	1	1	1	Positive Genetic
SIW14	YNL032W	Inositol phosphatase involved in inositol pyrophosphate metabolism	genetic	1	1	1	Positive Genetic
RPL2A	YFR031C-A	Ribosomal 60S subunit protein L2A	genetic	1	1	1	Positive Genetic
NPR3	YHL023C	Subunit of the Iml1p/SEACIT complex	genetic	1	1	1	Positive Genetic
NIT1	YIL164C	Nitrilase	genetic	1	1	1	Positive Genetic
PER33	YLR064W	Protein that localizes to the endoplasmic reticulum	genetic	1	1	1	Positive Genetic
RPS28B	YLR264W	Protein component of the small (40S) ribosomal subunit	genetic	1	1	1	Positive Genetic
TSA1	YML028W	Thioredoxin peroxidase	genetic	1	1	1	Positive Genetic
RER2	YBR002C	Forms the dehydrodolichyl diphosphate synthase (DDS) complex with NUS1	genetic	1	1	1	Negative Genetic
TSC3	YBR058C-A	Protein that stimulates the activity of serine palmitoyltransferase	genetic	1	1	1	Negative Genetic
RRP7	YCL031C	Essential protein involved in rRNA processing and ribosome biogenesis	genetic	1	1	1	Negative Genetic
PBN1	YCL052C	Component of glycosylphosphatidylinositol-mannosyltransferase I	genetic	1	1	1	Negative Genetic
TSC13	YDL015C	Enoyl reductase	genetic	1	1	1	Negative Genetic
TSR1	YDL060W	Protein required for processing of 20S pre-rRNA in the cytoplasm	genetic	1	1	1	Negative Genetic
UBC9	YDL064W	SUMO-conjugating enzyme involved in the Smt3p conjugation pathway	genetic	1	1	1	Negative Genetic
POL3	YDL102W	Catalytic subunit of DNA polymerase delta	genetic	1	1	1	Negative Genetic
SCM3	YDL139C	Nonhistone component of centromeric chromatin	genetic	1	1	1	Negative Genetic
SEC1	YDR164C	Sm-like protein involved in docking and fusion of exocytic vesicles	genetic	1	1	1	Negative Genetic
PRP2	YNR011C	RNA-dependent DExD/H-box ATPase	genetic	1	1	1	Negative Genetic
TFC6	YDR362C	Subunit of RNA polymerase III transcription initiation factor complex	genetic	1	1	1	Negative Genetic
NCB2	YDR397C	Subunit of a heterodimeric NC2 transcription regulator complex	genetic	1	1	1	Negative Genetic
RRP17	YDR412W	5' exoribonuclease required for 5' end processing of pre-60S rRNA	genetic	1	1	1	Negative Genetic
TLG1	YDR468C	Essential t-SNARE that mediates fusion of vesicles with the late Golgi	genetic	1	1	1	Negative Genetic
SPC25	YER018C	Component of the kinetochore-associated Ndc80 complex	genetic	1	1	1	Negative Genetic
KRE29	YER038C	Subunit of the SMC5-SMC6 complex	genetic	1	1	1	Negative Genetic
SPB4	YFL002C	Putative ATP-dependent RNA helicase	genetic	1	1	1	Negative Genetic
RNA15	YGL044C	Component of the cleavage and polyadenylation factor I (CF I)	genetic	1	1	1	Negative Genetic
SPC105	YGL093W	Subunit of a kinetochore-microtubule binding complex	genetic	1	1	1	Negative Genetic
SUA5	YGL169W	Protein involved in threonylcarbamoyl adenosine biosynthesis	genetic	1	1	1	Negative Genetic
MCM6	YGL201C	Protein involved in DNA replication	genetic	1	1	1	Negative Genetic
NOP19	YGR251W	Ribosome biogenesis factor	genetic	1	1	1	Negative Genetic
FUR1	YHR128W	Uracil phosphoribosyltransferase	genetic	1	1	1	Negative Genetic
SRP102	YKL154W	Signal recognition particle (SRP) receptor beta subunit	genetic	1	1	1	Negative Genetic
MIA40	YKL195W	Import and assembly protein in mitochondrial intermembrane space	genetic	1	1	1	Negative Genetic
FCF2	YLR051C	Nucleolar protein involved in the early steps of 35S rRNA processing	genetic	1	1	1	Negative Genetic
SEN2	YLR105C	Subunit of the tRNA splicing endonuclease	genetic	1	1	1	Negative Genetic
HSP60	YLR259C	Tetradecameric mitochondrial chaperonin	genetic	1	1	1	Negative Genetic
NSE5	YML023C	Component of the SMC5-SMC6 complex	genetic	1	1	1	Negative Genetic
TEM1	YML064C	GTPase involved in initiation of Mitotic Exit Network (MEN)	genetic	1	1	1	Negative Genetic
PRE8	YML092C	Alpha 2 subunit of the 20S proteasome	genetic	1	1	1	Negative Genetic
SEC65	YML105C	Subunit of the signal recognition particle (SRP)	genetic	1	1	1	Negative Genetic
NUP116	YMR047C	FG-nucleoporin component of central core of the nuclear pore complex	genetic	1	1	1	Negative Genetic
RIO2	YNL207W	Essential serine kinase involved in the processing of 20S pre-rRNA	genetic	1	1	1	Negative Genetic
POP1	YNL221C	Subunit of RNase MRP, nuclear RNase P and telomerase complexes	genetic	1	1	1	Negative Genetic
POL2	YNL262W	Catalytic subunit of DNA polymerase (II) epsilon	genetic	1	1	1	Negative Genetic
SEC2	YNL272C	Guanyl-nucleotide exchange factor for the small G-protein Sec4p	genetic	1	1	1	Negative Genetic
POP3	YNL282W	Subunit of both RNase MRP and nuclear RNase P	genetic	1	1	1	Negative Genetic
SGT1	YOR057W	Cochaperone protein	genetic	1	1	1	Negative Genetic
SUP35	YDR172W	Translation termination factor eRF3	genetic	1	1	1	Negative Genetic
TRS23	YDR246W	Core component of transport protein particle (TRAPP) complexes I-III	genetic	1	1	1	Negative Genetic
UTP6	YDR449C	Nucleolar protein	genetic	1	1	1	Negative Genetic
SNM1	YDR478W	Ribonuclease MRP complex subunit	genetic	1	1	1	Negative Genetic
SMT3	YDR510W	Ubiquitin-like protein of the SUMO family	genetic	1	1	1	Negative Genetic
SCC4	YER147C	Subunit of cohesin loading factor (Scc2p-Scc4p)	genetic	1	1	1	Negative Genetic
SEC4	YFL005W	Rab family GTPase	genetic	1	1	1	Negative Genetic
MOB2	YFL034C-B	Activator of Cbk1p kinase	genetic	1	1	1	Negative Genetic
TAF6	YGL112C	Subunit (60 kDa) of TFIID and SAGA complexes	genetic	1	1	1	Negative Genetic
MCM10	YIL150C	Essential chromatin-associated protein	genetic	1	1	1	Negative Genetic
PRI1	YIR008C	Subunit of DNA primase	genetic	1	1	1	Negative Genetic
ESS1	YJR017C	Peptidylprolyl-cis/trans-isomerase (PPIase)	genetic	1	1	1	Negative Genetic
TAH11	YJR046W	DNA replication licensing factor	genetic	1	1	1	Negative Genetic
RFC2	YJR068W	Subunit of heteropentameric Replication factor C (RF-C)	genetic	1	1	1	Negative Genetic
SSL1	YLR005W	Subunit of the core form of RNA polymerase transcription factor TFIIH	genetic	1	1	1	Negative Genetic
TAD3	YLR316C	Subunit of tRNA-specific adenosine-34 deaminase	genetic	1	1	1	Negative Genetic
ORC1	YML065W	Largest subunit of the origin recognition complex	genetic	1	1	1	Negative Genetic
SEC62	YPL094C	Essential subunit of Sec63 complex	genetic	1	1	1	Negative Genetic
IPL1	YPL209C	Aurora kinase of chromosomal passenger complex	genetic	1	1	1	Negative Genetic
NSL1	YPL233W	Essential component of the MIND kinetochore complex	genetic	1	1	1	Negative Genetic
ORC4	YPR162C	Subunit of the origin recognition complex (ORC)	genetic	1	1	1	Negative Genetic
SLU7	YDR088C	RNA splicing factor	genetic	1	1	1	Negative Genetic
GUK1	YDR454C	Guanylate kinase	genetic	1	1	1	Negative Genetic
GDI1	YER136W	GDP dissociation inhibitor	genetic	1	1	1	Negative Genetic
NUP145	YGL092W	Essential protein with distinct roles in two nuclear pore subcomplexes	genetic	1	1	1	Negative Genetic
TIP20	YGL145W	Peripheral membrane protein required for COPI vesicle fusion to the ER	genetic	1	1	1	Negative Genetic
RHO3	YIL118W	Non-essential small GTPase of the Rho/Rac family of Ras-like proteins	genetic	1	1	1	Negative Genetic
GRC3	YLL035W	Polynucleotide kinase present on rDNA	genetic	1	1	1	Negative Genetic
RPC34	YNR003C	RNA polymerase III subunit C34	genetic	1	1	1	Negative Genetic
TFB2	YPL122C	Subunit of TFIIH and nucleotide excision repair factor 3 complexes	genetic	1	1	1	Negative Genetic
RAD53	YPL153C	DNA damage response kinase	genetic	1	1	1	Negative Genetic
YTH1	YPR107C	Essential RNA-binding component of cleavage and polyadenylation factor	genetic	1	1	1	Negative Genetic
PZF1	YPR186C	Transcription factor IIIA (TFIIIA)	genetic	1	1	1	Negative Genetic
POT1	YIL160C	3-ketoacyl-CoA thiolase with broad chain length specificity	genetic	1	1	1	Negative Genetic
SYS1	YJL004C	Integral membrane protein of the Golgi	genetic	1	1	1	Negative Genetic
HIR3	YJR140C	Subunit of the HIR complex	genetic	1	1	1	Negative Genetic
NUP133	YKR082W	Subunit of Nup84p subcomplex of nuclear pore complex (NPC)	genetic	1	1	1	Negative Genetic
TMA23	YMR269W	Nucleolar protein implicated in ribosome biogenesis	genetic	1	1	1	Negative Genetic
JNM1	YMR294W	Component of the yeast dynactin complex	genetic	1	1	1	Negative Genetic
MKS1	YNL076W	Pleiotropic negative transcriptional regulator	genetic	1	1	1	Negative Genetic
RMI1	YPL024W	Subunit of the RecQ (Sgs1p) - Topo III (Top3p) complex	genetic	1	1	1	Negative Genetic
PMA2	YPL036W	Plasma membrane H+-ATPase	genetic	1	1	1	Negative Genetic
ISR1	YPR106W	Predicted protein kinase	genetic	1	1	1	Negative Genetic
GIP1	YBR045C	Meiosis-specific regulatory subunit of the Glc7p protein phosphatase	genetic	1	1	1	Negative Genetic
RIM1	YCR028C-A	ssDNA-binding protein essential for mitochondrial genome maintenance	genetic	1	1	1	Negative Genetic
YCR102C	YCR102C	Putative quinone oxidoreductase	genetic	1	1	1	Negative Genetic
YDL012C	YDL012C	Tail-anchored plasma membrane protein with a conserved CYSTM module	genetic	1	1	1	Negative Genetic
PPH22	YDL188C	Catalytic subunit of protein phosphatase 2A, PP2A	genetic	1	1	1	Negative Genetic
TPS2	YDR074W	Phosphatase subunit of the trehalose-6-P synthase/phosphatase complex	genetic	1	1	1	Negative Genetic
HOM2	YDR158W	Aspartic beta semi-aldehyde dehydrogenase	genetic	1	1	1	Negative Genetic
SIZ1	YDR409W	SUMO E3 ligase	genetic	1	1	1	Negative Genetic
RMR1	YGL250W	Protein required for meiotic recombination and gene conversion	genetic	1	1	1	Negative Genetic
PFK26	YIL107C	6-phosphofructo-2-kinase	genetic	1	1	1	Negative Genetic
VTH1	YIL173W	Putative membrane glycoprotein	genetic	1	1	1	Negative Genetic
SDH9	YJL045W	Minor succinate dehydrogenase isozyme	genetic	1	1	1	Negative Genetic
TPK3	YKL166C	cAMP-dependent protein kinase catalytic subunit	genetic	1	1	1	Negative Genetic
UTP30	YKR060W	Subunit of U3-containing 90S preribosome complex	genetic	1	1	1	Negative Genetic
RAX2	YLR084C	Protein required for the maintenance of bud site selection	genetic	1	1	1	Negative Genetic
ICT1	YLR099C	Lysophosphatidic acid acyltransferase	genetic	1	1	1	Negative Genetic
VIP1	YLR410W	Bifunctional inositol pyrophosphate kinase and phosphatase	genetic	1	1	1	Negative Genetic
TSR2	YLR435W	Protein with a potential role in pre-rRNA processing	genetic	1	1	1	Negative Genetic
YNL115C	YNL115C	Putative protein of unknown function	genetic	1	1	1	Negative Genetic
GIM3	YNL153C	Subunit of the heterohexameric cochaperone prefoldin complex	genetic	1	1	1	Negative Genetic
YNR064C	YNR064C	Epoxide hydrolase	genetic	1	1	1	Negative Genetic
YBR137W	YBR137W	Protein with a role in ER delivery of tail-anchored membrane proteins	genetic	1	1	1	Negative Genetic
PEX32	YBR168W	Peroxisomal integral membrane protein	genetic	1	1	1	Negative Genetic
VMA9	YCL005W-A	Vacuolar H+ ATPase subunit e of the V-ATPase V0 subcomplex	genetic	1	1	1	Negative Genetic
HTL1	YCR020W-B	Component of the RSC chromatin remodeling complex	genetic	1	1	1	Negative Genetic
SED4	YCR067C	Integral ER membrane protein that stimulates Sar1p GTPase activity	genetic	1	1	1	Negative Genetic
VTC5	YDR089W	Novel subunit of the vacuolar transporter chaperone complex	genetic	1	1	1	Negative Genetic
TRP4	YDR354W	Anthranilate phosphoribosyl transferase	genetic	1	1	1	Negative Genetic
GIM4	YEL003W	Subunit of the heterohexameric cochaperone prefoldin complex	genetic	1	1	1	Negative Genetic
RPL34A	YER056C-A	Ribosomal 60S subunit protein L34A	genetic	1	1	1	Negative Genetic
SWP82	YFL049W	Member of the SWI/SNF chromatin remodeling complex	genetic	1	1	1	Negative Genetic
SNG1	YGR197C	Protein involved in resistance to nitrosoguanidine and 6-azauracil	genetic	1	1	1	Negative Genetic
YHL008C	YHL008C	Putative protein of unknown function	genetic	1	1	1	Negative Genetic
MCO14	YHL018W	Putative 4a-hydroxytetrahydrobiopterin dehydratase	genetic	1	1	1	Negative Genetic
SCH9	YHR205W	AGC family protein kinase	genetic	1	1	1	Negative Genetic
YIL134C-A	YIL134C-A	Putative protein of unknown function	genetic	1	1	1	Negative Genetic
IDS2	YJL146W	Protein involved in modulation of Ime2p activity during meiosis	genetic	1	1	1	Negative Genetic
PLN1	YKR046C	Perilipin, involved in formation and stability of lipid droplets	genetic	1	1	1	Negative Genetic
NDL1	YLR254C	Homolog of nuclear distribution factor NudE	genetic	1	1	1	Negative Genetic
SMA2	YML066C	Meiosis-specific prospore membrane protein	genetic	1	1	1	Negative Genetic
HSC82	YMR186W	Cytoplasmic chaperone of the Hsp90 family	genetic	1	1	1	Negative Genetic
YMR272W-B	YMR272W-B	Protein of unknown function	genetic	1	1	1	Negative Genetic
SLM2	YNL047C	Phosphoinositide PI4,5P(2) binding protein, forms a complex with Slm1p	genetic	1	1	1	Negative Genetic
SFB2	YNL049C	Component of the Sec23p-Sfb2p heterodimer of the COPII vesicle coat	genetic	1	1	1	Negative Genetic
INP52	YNL106C	Polyphosphatidylinositol phosphatase	genetic	1	1	1	Negative Genetic
IBD2	YNL164C	Component of the BUB2-dependent spindle checkpoint pathway	genetic	1	1	1	Negative Genetic
SIN4	YNL236W	Subunit of the RNA polymerase II mediator complex	genetic	1	1	1	Negative Genetic
SLA2	YNL243W	Adaptor protein that links actin to clathrin and endocytosis	genetic	1	1	1	Negative Genetic
TRF5	YNL299W	Non-canonical poly(A) polymerase	genetic	1	1	1	Negative Genetic
MAN2	YNR073C	Mannitol dehydrogenase	genetic	1	1	1	Negative Genetic
YOR072W-B	YOR072W-B	Putative protein of unknown function	genetic	1	1	1	Negative Genetic
SMA1	YPL027W	Protein of unknown function involved in prospore membrane assembly	genetic	1	1	1	Negative Genetic
YPL150W	YPL150W	Protein kinase of unknown cellular role	genetic	1	1	1	Negative Genetic
YPR159C-A	YPR159C-A	Protein of unknown function	genetic	1	1	1	Negative Genetic
HOS1	YPR068C	Class I histone deacetylase (HDAC) family member	genetic	1	1	1	Synthetic Growth Defect
HOS4	YIL112W	Subunit of the Set3 complex	genetic	1	1	1	Synthetic Rescue
SET3	YKR029C	Defining member of the SET3 histone deacetylase complex	genetic	1	1	1	Synthetic Rescue
RET2	YFR051C	Delta subunit of the coatomer complex (COPI)	genetic	1	1	1	Negative Genetic
KRE1	YNL322C	Cell wall glycoprotein involved in beta-glucan assembly	genetic	1	1	1	Negative Genetic
SPN1	YPR133C	Protein involved in RNA polymerase II transcription	genetic	1	1	1	Negative Genetic
KES1	YPL145C	Sterol/phosphatidylinositol-4-phosphate (PI(4)P) exchanger	genetic	1	1	1	Synthetic Growth Defect
OKP1	YGR179C	Outer kinetochore protein required for accurate chromosome segregation	genetic	1	1	1	Negative Genetic
SRN2	YLR119W	Component of the ESCRT-I complex	genetic	1	1	1	Negative Genetic
JHD2	YJR119C	JmjC domain family histone demethylase	genetic	1	1	1	Synthetic Rescue
HRQ1	YDR291W	3'-5' DNA helicase of the conserved RecQ family	genetic	1	1	1	Negative Genetic
BRX1	YOL077C	Nucleolar protein	physical	1	1	1	Biochemical Activity
CDC48	YDL126C	AAA ATPase with protein-unfoldase activity	genetic	1	1	1	Positive Genetic
ARP7	YPR034W	Component of both the SWI/SNF and RSC chromatin remodeling complexes	genetic	1	1	1	Negative Genetic
AAR2	YBL074C	Component of the U5 snRNP complex	genetic	1	1	1	Negative Genetic
ALA1	YOR335C	Cytoplasmic and mitochondrial alanyl-tRNA synthetase	physical	1	1	1	Biochemical Activity
CCR4	YAL021C	Component of the CCR4-NOT transcriptional complex	physical	1	1	1	Affinity Capture-RNA
ECM16	YMR128W	Essential DEAH-box ATP-dependent RNA helicase specific to U3 snoRNP	physical	1	1	1	Affinity Capture-MS
ABD1	YBR236C	Methyltransferase	genetic	1	1	1	Negative Genetic
ASF1	YJL115W	Nucleosome assembly factor	physical	1	1	1	Biochemical Activity
BET3	YKR068C	Core component of transport protein particle (TRAPP) complexes I-III	genetic	1	1	1	Negative Genetic
BET2	YPR176C	Beta subunit of Type II geranylgeranyltransferase	genetic	1	1	1	Negative Genetic
BMH2	YDR099W	14-3-3 protein, minor isoform	physical	1	1	1	Affinity Capture-Western
BMH2	YDR099W	14-3-3 protein, minor isoform	genetic	1	1	1	Synthetic Lethality
ASC1	YMR116C	G-protein beta subunit and guanine dissociation inhibitor for Gpa2p	genetic	1	1	1	Positive Genetic
BEM2	YER155C	Rho GTPase activating protein (RhoGAP)	genetic	1	1	1	Positive Genetic
CDC14	YFR028C	Protein phosphatase required for mitotic exit	physical	1	1	1	Affinity Capture-MS
CDC11	YJR076C	Component of the septin ring that is required for cytokinesis	physical	1	1	1	Biochemical Activity
CDC11	YJR076C	Component of the septin ring that is required for cytokinesis	genetic	1	1	1	Negative Genetic
CDC12	YHR107C	Component of the septin ring that is required for cytokinesis	physical	1	1	1	Biochemical Activity
CDC3	YLR314C	Component of the septin ring that is required for cytokinesis	physical	1	1	1	Biochemical Activity
CDC36	YDL165W	Component of the CCR4-NOT core complex, involved in mRNA decapping	genetic	1	1	1	Negative Genetic
ERG26	YGL001C	C-3 sterol dehydrogenase	genetic	1	1	1	Negative Genetic
DBP10	YDL031W	Putative ATP-dependent RNA helicase of the DEAD-box protein family	physical	1	1	1	Biochemical Activity
CEG1	YGL130W	Guanylyltransferase involved in mRNA 5' capping	genetic	1	1	1	Negative Genetic
AVO1	YOL078W	Component of the membrane-bound TORC2 complex	genetic	1	1	1	Positive Genetic
CKS1	YBR135W	Cyclin-dependent protein kinase regulatory subunit and adaptor	genetic	1	1	1	Negative Genetic
COP1	YDL145C	Alpha subunit of COPI vesicle coatomer complex	physical	1	1	1	Affinity Capture-MS
CIA2	YHR122W	Component of cytosolic iron-sulfur protein assembly (CIA) machinery	genetic	1	1	1	Negative Genetic
EDE1	YBL047C	Scaffold protein involved in the formation of early endocytic sites	physical	1	1	1	Biochemical Activity
EMG1	YLR186W	Methyltransferase for rRNA	genetic	1	1	1	Negative Genetic
CCT4	YDL143W	Subunit of the cytosolic chaperonin Cct ring complex	physical	1	1	1	Affinity Capture-MS
ERV25	YML012W	Member of the p24 family involved in ER to Golgi transport	genetic	1	1	1	Negative Genetic
BDF2	YDL070W	Protein involved in transcription initiation	physical	1	1	1	Biochemical Activity
DHH1	YDL160C	Cytoplasmic DEAD-box helicase and mRNA decapping activator	physical	1	1	1	Affinity Capture-RNA
CLU1	YMR012W	Subunit of the eukaryotic translation initiation factor 3 (eIF3)	physical	1	1	1	Affinity Capture-MS
CRM1	YGR218W	Nuclear export factor, exportin	physical	1	1	1	Affinity Capture-MS
CMD1	YBR109C	Calmodulin	physical	1	1	1	Affinity Capture-MS
CMD1	YBR109C	Calmodulin	genetic	1	1	1	Negative Genetic
ATG18	YFR021W	Phosphoinositide binding protein	genetic	1	1	1	Negative Genetic
AFG2	YLR397C	ATPase of the CDC48/PAS1/SEC18 (AAA) family, forms a hexameric complex	physical	1	1	1	Biochemical Activity
BLM10	YFL007W	Proteasome activator	physical	1	1	1	Affinity Capture-MS
BUD21	YOR078W	Component of small ribosomal subunit (SSU) processosome	genetic	1	1	1	Negative Genetic
CCT2	YIL142W	Subunit beta of the cytosolic chaperonin Cct ring complex	physical	1	1	1	Biochemical Activity
CCT8	YJL008C	Subunit of the cytosolic chaperonin Cct ring complex	physical	1	1	1	Affinity Capture-MS
CCT8	YJL008C	Subunit of the cytosolic chaperonin Cct ring complex	genetic	1	1	1	Negative Genetic
CCT6	YDR188W	Subunit of the cytosolic chaperonin Cct ring complex	genetic	1	1	1	Negative Genetic
BET5	YML077W	Core component of transport protein particle (TRAPP) complexes I-III	genetic	1	1	1	Positive Genetic
CAB5	YDR196C	Subunit of the CoA-Synthesizing Protein Complex (CoA-SPC)	genetic	1	1	1	Negative Genetic
AIM17	YHL021C	Protein of unknown function	genetic	1	1	1	Negative Genetic
BNA3	YJL060W	Kynurenine aminotransferase	genetic	1	1	1	Negative Genetic
ABP1	YCR088W	Actin-binding protein of the cortical actin cytoskeleton	genetic	1	1	1	Negative Genetic
APP1	YNL094W	Phosphatidate phosphatase, converts phosphatidate to diacylglycerol	physical	1	1	1	Biochemical Activity
ARF1	YDL192W	ADP-ribosylation factor	physical	1	1	1	Affinity Capture-MS
BUB2	YMR055C	Mitotic exit network regulator	physical	1	1	1	Affinity Capture-MS
AHP1	YLR109W	Thiol-specific peroxiredoxin	genetic	1	1	1	Negative Genetic
CHK1	YBR274W	Serine/threonine kinase and DNA damage checkpoint effector	genetic	1	1	1	Positive Genetic
BFA1	YJR053W	Subunit of a two-component GTPase-activating protein, Bfa1p-Bub2p	physical	1	1	1	Affinity Capture-MS
CDC9	YDL164C	DNA ligase I found in nucleus and mitochondria	genetic	1	1	1	Negative Genetic
COF1	YLL050C	Cofilin, involved in pH-dependent actin filament depolarization	genetic	1	1	1	Positive Genetic
ATG11	YPR049C	Adapter protein for pexophagy and the Cvt targeting pathway	physical	1	1	1	Biochemical Activity
CCT3	YJL014W	Subunit of the cytosolic chaperonin Cct ring complex	genetic	1	1	1	Negative Genetic
ART10	YLR392C	Protein of unknown function that contains 2 PY motifs	genetic	1	1	1	Negative Genetic
CDC60	YPL160W	Cytosolic leucyl tRNA synthetase	genetic	1	1	1	Negative Genetic
CTF13	YMR094W	Subunit of the CBF3 complex	genetic	1	1	1	Negative Genetic
ADD66	YKL206C	Protein involved in 20S proteasome assembly	physical	1	1	1	Biochemical Activity
CTF4	YPR135W	Chromatin-associated protein	physical	1	1	1	Biochemical Activity
DUT1	YBR252W	Deoxyuridine triphosphate diphosphatase (dUTPase)	genetic	1	1	1	Negative Genetic
DEF1	YKL054C	RNAPII degradation factor	physical	1	1	1	Affinity Capture-MS
CSC1	YLR241W	Calcium permeable gated cation channel	genetic	1	1	1	Negative Genetic
CHZ1	YER030W	Histone chaperone for Htz1p/H2A-H2B dimer	physical	1	1	1	Biochemical Activity
ERG11	YHR007C	Lanosterol 14-alpha-demethylase	genetic	1	1	1	Negative Genetic
DAD1	YDR016C	Essential subunit of the Dam1 complex (aka DASH complex)	genetic	1	1	1	Negative Genetic
DUO1	YGL061C	Essential subunit of the Dam1 complex (aka DASH complex)	genetic	1	1	1	Negative Genetic
DSL1	YNL258C	Peripheral membrane protein needed for Golgi-to-ER retrograde traffic	genetic	1	1	1	Positive Genetic
CDC43	YGL155W	Beta subunit of geranylgeranyltransferase type I	genetic	1	1	1	Negative Genetic
AQY2	YLL052C	Water channel that mediates water transport across cell membranes	genetic	1	1	1	Negative Genetic
CWC24	YLR323C	General splicing factor	genetic	1	1	1	Negative Genetic
ASM4	YDL088C	FG-nucleoporin component of central core of nuclear pore complex (NPC)	genetic	1	1	1	Negative Genetic
DON1	YDR273W	Meiosis-specific component of the spindle pole body	physical	1	1	1	Biochemical Activity
CDC34	YDR054C	Ubiquitin-conjugating enzyme (E2)	physical	1	1	1	Biochemical Activity
CUB1	YPL260W	Conserved fungal gene linked to DNA repair and proteasome function	physical	1	1	1	Biochemical Activity
COG4	YPR105C	Essential component of the conserved oligomeric Golgi complex	genetic	1	1	1	Negative Genetic
CEP3	YMR168C	Essential kinetochore protein	genetic	1	1	1	Negative Genetic
CET1	YPL228W	RNA 5'-triphosphatase involved in mRNA 5' capping	genetic	1	1	1	Negative Genetic
CDC31	YOR257W	Calcium-binding component of the spindle pole body (SPB) half-bridge	physical	1	1	1	Affinity Capture-MS
BUB1	YGR188C	Protein kinase involved in the cell cycle checkpoint into anaphase	genetic	1	1	1	Synthetic Lethality
BUD4	YJR092W	Anillin-like protein involved in bud-site selection	genetic	1	1	1	Positive Genetic
DBF4	YDR052C	Regulatory subunit of Cdc7p-Dbf4p kinase complex	genetic	1	1	1	Negative Genetic
BNI5	YNL166C	Linker protein responsible for recruitment of myosin to the bud neck	physical	1	1	1	Biochemical Activity
BET1	YIL004C	Type II membrane protein required for vesicular transport	genetic	1	1	1	Negative Genetic
BBP1	YPL255W	Protein required for the spindle pole body (SPB) duplication	physical	1	1	1	Affinity Capture-MS
DPH2	YKL191W	Protein required for synthesis of diphthamide	physical	1	1	1	Biochemical Activity
EMP46	YLR080W	Integral membrane component of ER-derived COPII-coated vesicles	genetic	1	1	1	Negative Genetic
CDC19	YAL038W	Pyruvate kinase	genetic	1	1	1	Negative Genetic
CHS5	YLR330W	Component of the exomer complex	physical	1	1	1	Biochemical Activity
ERV29	YGR284C	Protein localized to COPII-coated vesicles	genetic	1	1	1	Negative Genetic
BET4	YJL031C	Alpha subunit of Type II geranylgeranyltransferase	genetic	1	1	1	Negative Genetic
ERF2	YLR246W	Subunit of a palmitoyltransferase	genetic	1	1	1	Negative Genetic
DBP6	YNR038W	Essential protein involved in ribosome biogenesis	physical	1	1	1	Biochemical Activity
ERV14	YGL054C	COPII-coated vesicle protein	genetic	1	1	1	Negative Genetic
ABZ1	YNR033W	Para-aminobenzoate (PABA) synthase	physical	1	1	1	Biochemical Activity
BUG1	YDL099W	Cis-golgi localized protein involved in ER to Golgi transport	genetic	1	1	1	Negative Genetic
ASG7	YJL170C	Protein that regulates signaling from G protein beta subunit Ste4p	genetic	1	1	1	Negative Genetic
BAP3	YDR046C	Amino acid permease	genetic	1	1	1	Negative Genetic
ARI1	YGL157W	NADPH-dependent aldehyde reductase	genetic	1	1	1	Positive Genetic
CUE3	YGL110C	Subunit of ribosome-associated quality control trigger complex (RQT)	physical	1	1	1	Biochemical Activity
CSR1	YLR380W	Phosphatidylinositol transfer protein	genetic	1	1	1	Negative Genetic
CAB4	YGR277C	Subunit of the CoA-Synthesizing Protein Complex (CoA-SPC)	genetic	1	1	1	Negative Genetic
ELF1	YKL160W	Transcription elongation factor with a conserved zinc finger domain	physical	1	1	1	Biochemical Activity
DIN7	YDR263C	Mitochondrial nuclease functioning in DNA repair and replication	genetic	1	1	1	Negative Genetic
EFM6	YNL024C	Putative S-adenosylmethionine-dependent lysine methyltransferase	genetic	1	1	1	Negative Genetic
COA3	YJL062W-A	Mitochondrial protein required for cytochrome c oxidase assembly	genetic	1	1	1	Negative Genetic
ABZ2	YMR289W	Aminodeoxychorismate lyase (4-amino-4-deoxychorismate lyase)	genetic	1	1	1	Positive Genetic
ABP140	YOR239W	AdoMet-dependent tRNA methyltransferase and actin binding protein	physical	1	1	1	Biochemical Activity
CAB1	YDR531W	Pantothenate kinase, ATP:D-pantothenate 4'-phosphotransferase	genetic	1	1	1	Negative Genetic
ENT4	YLL038C	Protein of unknown function	genetic	1	1	1	Positive Genetic
COS7	YDL248W	Endosomal protein involved in turnover of plasma membrane proteins	genetic	1	1	1	Negative Genetic
DYN3	YMR299C	Dynein light intermediate chain (LIC)	genetic	1	1	1	Negative Genetic
ARO7	YPR060C	Chorismate mutase	genetic	1	1	1	Negative Genetic
CDC8	YJR057W	Nucleoside monophosphate and nucleoside diphosphate kinase	genetic	1	1	1	Negative Genetic
AFB1	YLR040C	MATalpha-specific a-factor blocker	genetic	1	1	1	Negative Genetic
APA2	YDR530C	Diadenosine 5',5'''-P1,P4-tetraphosphate phosphorylase II	physical	1	1	1	Biochemical Activity
EFM5	YGR001C	S-adenosylmethionine-dependent lysine methyltransferase	physical	1	1	1	Biochemical Activity
CDC1	YDR182W	Putative mannose-ethanolamine phosphate phosphodiesterase	genetic	1	1	1	Negative Genetic
DIT2	YDR402C	N-formyltyrosine oxidase	genetic	1	1	1	Positive Genetic
CTR86	YCR054C	Essential protein of unknown function	genetic	1	1	1	Negative Genetic
ATR2	YMR279C	Putative boron transporter involved in boron efflux and resistance	genetic	1	1	1	Negative Genetic
BMT6	YLR063W	Methyltransferase required for m3U2843 methylation of the 25S rRNA	genetic	1	1	1	Negative Genetic