STI1 |
YOR027W |
Evolutionarily-conserved Hsp90 cochaperone |
physical |
35 |
6 |
33 |
Reconstituted Complex, Reconstituted Complex, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-MS, Two-hybrid, Affinity Capture-Western, Co-purification, Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Co-crystal Structure, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-MS, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-Western |
AHA1 |
YDR214W |
Co-chaperone that binds Hsp82p and activates its ATPase activity |
physical |
29 |
5 |
24 |
Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Two-hybrid, Affinity Capture-MS, Two-hybrid, Reconstituted Complex, Affinity Capture-MS, Two-hybrid, Two-hybrid, Reconstituted Complex, Two-hybrid, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Reconstituted Complex, FRET, Reconstituted Complex, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western |
SBA1 |
YKL117W |
Co-chaperone that binds and regulates Hsp90 family chaperones |
physical |
25 |
6 |
21 |
Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Two-hybrid, Reconstituted Complex, Co-crystal Structure, Affinity Capture-Western, Biochemical Activity, Two-hybrid, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex |
HSP82 |
YPL240C |
Hsp90 chaperone |
physical |
17 |
6 |
17 |
Affinity Capture-Western, Protein-peptide, Reconstituted Complex, Co-crystal Structure, Co-crystal Structure, Reconstituted Complex, Reconstituted Complex, FRET, Affinity Capture-Western, Affinity Capture-MS, Co-crystal Structure, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-MS, Reconstituted Complex |
CPR6 |
YLR216C |
Peptidyl-prolyl cis-trans isomerase (cyclophilin) |
physical |
17 |
4 |
14 |
Reconstituted Complex, Reconstituted Complex, Affinity Capture-Western, Reconstituted Complex, Two-hybrid, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-MS |
SSA1 |
YAL005C |
ATPase involved in protein folding and NLS-directed nuclear transport |
physical |
15 |
3 |
11 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex |
CDC37 |
YDR168W |
Essential Hsp90p co-chaperone |
physical |
12 |
4 |
11 |
Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Two-hybrid, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-MS |
CPR7 |
YJR032W |
Peptidyl-prolyl cis-trans isomerase (cyclophilin) |
physical |
11 |
5 |
10 |
Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Protein-peptide |
TAH1 |
YCR060W |
Component of conserved R2TP complex (Rvb1-Rvb2-Tah1-Pih1) |
physical |
11 |
4 |
8 |
Reconstituted Complex, Two-hybrid, Two-hybrid, Two-hybrid, Reconstituted Complex, Affinity Capture-MS, Reconstituted Complex, Reconstituted Complex, Co-crystal Structure, Two-hybrid, Reconstituted Complex |
CNS1 |
YBR155W |
TPR-containing co-chaperone |
physical |
11 |
4 |
7 |
Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Two-hybrid, Affinity Capture-MS, Two-hybrid, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-MS |
PPT1 |
YGR123C |
Protein serine/threonine phosphatase |
physical |
8 |
5 |
7 |
Affinity Capture-MS, Two-hybrid, Affinity Capture-MS, Affinity Capture-MS, Biochemical Activity, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-MS |
STI1 |
YOR027W |
Evolutionarily-conserved Hsp90 cochaperone |
genetic |
8 |
3 |
7 |
Synthetic Growth Defect, Dosage Rescue, Synthetic Lethality, Synthetic Growth Defect, Synthetic Lethality, Synthetic Growth Defect, Synthetic Lethality, Dosage Rescue |
SSA2 |
YLL024C |
HSP70 family ATP-binding protein |
physical |
8 |
3 |
7 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-MS, Reconstituted Complex |
YDJ1 |
YNL064C |
Type I HSP40 co-chaperone |
physical |
7 |
5 |
7 |
Affinity Capture-Western, Two-hybrid, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex |
HSC82 |
YMR186W |
Cytoplasmic chaperone of the Hsp90 family |
genetic |
7 |
3 |
6 |
Synthetic Lethality, Synthetic Growth Defect, Negative Genetic, Synthetic Growth Defect, Synthetic Lethality, Negative Genetic, Negative Genetic |
SSB1 |
YDL229W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
7 |
1 |
6 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
HCH1 |
YNL281W |
Heat shock protein regulator |
physical |
6 |
4 |
6 |
Two-hybrid, Affinity Capture-MS, Two-hybrid, Affinity Capture-Western, Affinity Capture-MS, Reconstituted Complex |
SSE1 |
YPL106C |
ATPase component of heat shock protein Hsp90 chaperone complex |
physical |
6 |
3 |
5 |
Affinity Capture-Western, Affinity Capture-MS, Two-hybrid, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
SLT2 |
YHR030C |
Serine/threonine MAP kinase |
physical |
6 |
2 |
4 |
Two-hybrid, Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Affinity Capture-Western, Affinity Capture-Western |
STE11 |
YLR362W |
Signal transducing MEK kinase |
physical |
5 |
3 |
5 |
Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Reconstituted Complex, Affinity Capture-Western |
SGT1 |
YOR057W |
Cochaperone protein |
physical |
5 |
3 |
5 |
Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-MS |
TDH3 |
YGR192C |
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 3 |
physical |
5 |
1 |
5 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
RPS3 |
YNL178W |
Protein component of the small (40S) ribosomal subunit |
physical |
5 |
1 |
5 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
RPS18A |
YDR450W |
Protein component of the small (40S) ribosomal subunit |
physical |
5 |
1 |
5 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
RPS27A |
YKL156W |
Protein component of the small (40S) ribosomal subunit |
physical |
5 |
1 |
5 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
CDC19 |
YAL038W |
Pyruvate kinase |
physical |
5 |
1 |
5 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
HSC82 |
YMR186W |
Cytoplasmic chaperone of the Hsp90 family |
physical |
5 |
2 |
4 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western |
RNR4 |
YGR180C |
Ribonucleotide-diphosphate reductase (RNR) small subunit |
physical |
5 |
2 |
4 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS |
SSB2 |
YNL209W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
5 |
2 |
4 |
Affinity Capture-MS, Affinity Capture-MS, Co-purification, Affinity Capture-MS, Affinity Capture-MS |
HCH1 |
YNL281W |
Heat shock protein regulator |
genetic |
5 |
3 |
3 |
Dosage Rescue, Synthetic Rescue, Dosage Lethality, Dosage Rescue, Dosage Rescue |
ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
physical |
4 |
2 |
4 |
Two-hybrid, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
RPS7B |
YNL096C |
Protein component of the small (40S) ribosomal subunit |
physical |
4 |
2 |
4 |
Two-hybrid, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
PUF3 |
YLL013C |
Protein of the mitochondrial outer surface |
physical |
4 |
2 |
4 |
Affinity Capture-RNA, Affinity Capture-MS, Affinity Capture-RNA, Affinity Capture-RNA |
ARC1 |
YGL105W |
Protein that binds tRNA and methionyl- and glutamyl-tRNA synthetases |
physical |
4 |
1 |
4 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
MOT3 |
YMR070W |
Transcriptional repressor, activator |
physical |
4 |
1 |
4 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
SEC23 |
YPR181C |
GTPase-activating protein, stimulates the GTPase activity of Sar1p |
physical |
4 |
1 |
4 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
RPS5 |
YJR123W |
Protein component of the small (40S) ribosomal subunit |
physical |
4 |
1 |
4 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
RPS0A |
YGR214W |
Ribosomal 40S subunit protein S0A |
physical |
4 |
1 |
4 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
RPS13 |
YDR064W |
Protein component of the small (40S) ribosomal subunit |
physical |
4 |
1 |
4 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
SSC1 |
YJR045C |
Hsp70 family ATPase |
physical |
4 |
1 |
4 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
RPS22A |
YJL190C |
Protein component of the small (40S) ribosomal subunit |
physical |
4 |
1 |
4 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
RPS20 |
YHL015W |
Protein component of the small (40S) ribosomal subunit |
physical |
4 |
1 |
4 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
PAA1 |
YDR071C |
Polyamine acetyltransferase |
physical |
4 |
1 |
4 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
RPL31A |
YDL075W |
Ribosomal 60S subunit protein L31A |
physical |
4 |
1 |
4 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
TUF1 |
YOR187W |
Mitochondrial translation elongation factor Tu (EF-Tu) |
physical |
4 |
1 |
4 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
MET17 |
YLR303W |
O-acetyl homoserine-O-acetyl serine sulfhydrylase |
physical |
4 |
1 |
4 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
DEF1 |
YKL054C |
RNAPII degradation factor |
physical |
4 |
1 |
4 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
SSZ1 |
YHR064C |
Hsp70 protein that interacts with Zuo1p (a DnaJ homolog) |
physical |
4 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
CLA4 |
YNL298W |
Cdc42p-activated signal transducing kinase |
genetic |
3 |
3 |
3 |
Synthetic Lethality, Synthetic Growth Defect, Phenotypic Suppression |
HSF1 |
YGL073W |
Trimeric heat shock transcription factor |
regulation |
3 |
2 |
3 |
DNA to cDNA expression microarray evidence, DNA to cDNA expression microarray evidence, two-dimensional polyacrylamide gel electrophoresis evidence |
CNS1 |
YBR155W |
TPR-containing co-chaperone |
genetic |
3 |
2 |
3 |
Synthetic Growth Defect, Synthetic Growth Defect, Dosage Rescue |
DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
3 |
2 |
3 |
Affinity Capture-RNA, Affinity Capture-RNA, Affinity Capture-MS |
SKP1 |
YDR328C |
Evolutionarily conserved kinetochore protein |
genetic |
3 |
2 |
3 |
Synthetic Lethality, Synthetic Growth Defect, Synthetic Growth Defect |
RTG3 |
YBL103C |
bHLH/Zip transcription factor for retrograde (RTG) and TOR pathways |
physical |
3 |
2 |
3 |
Two-hybrid, Affinity Capture-MS, Affinity Capture-MS |
TDH2 |
YJR009C |
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 2 |
physical |
3 |
2 |
3 |
Two-hybrid, Affinity Capture-MS, Affinity Capture-MS |
RPL25 |
YOL127W |
Ribosomal 60S subunit protein L25 |
physical |
3 |
2 |
3 |
Two-hybrid, Affinity Capture-MS, Affinity Capture-MS |
YPT6 |
YLR262C |
Rab family GTPase |
genetic |
3 |
2 |
3 |
Synthetic Lethality, Synthetic Growth Defect, Synthetic Growth Defect |
VMA4 |
YOR332W |
Subunit E of the V1 domain of the vacuolar H+-ATPase (V-ATPase) |
physical |
3 |
2 |
3 |
Affinity Capture-MS, Two-hybrid, Affinity Capture-MS |
RPL18A |
YOL120C |
Ribosomal 60S subunit protein L18A |
physical |
3 |
2 |
3 |
Two-hybrid, Affinity Capture-MS, Affinity Capture-MS |
UGP1 |
YKL035W |
UDP-glucose pyrophosphorylase (UGPase) |
physical |
3 |
2 |
3 |
Two-hybrid, Affinity Capture-MS, Affinity Capture-MS |
RPS2 |
YGL123W |
Protein component of the small (40S) subunit |
physical |
3 |
2 |
3 |
Affinity Capture-MS, Proximity Label-MS, Affinity Capture-MS |
PMT2 |
YAL023C |
Protein O-mannosyltransferase of the ER membrane |
genetic |
3 |
2 |
3 |
Synthetic Lethality, Synthetic Growth Defect, Synthetic Growth Defect |
LIN1 |
YHR156C |
Non-essential component of U5 snRNP |
genetic |
3 |
2 |
3 |
Synthetic Lethality, Synthetic Growth Defect, Synthetic Growth Defect |
GND1 |
YHR183W |
6-phosphogluconate dehydrogenase (decarboxylating) |
physical |
3 |
2 |
3 |
Two-hybrid, Affinity Capture-MS, Affinity Capture-MS |
CWC15 |
YDR163W |
Non-essential protein involved in pre-mRNA splicing |
physical |
3 |
2 |
3 |
Two-hybrid, Affinity Capture-MS, Affinity Capture-MS |
HAP1 |
YLR256W |
Zinc finger transcription factor |
physical |
3 |
2 |
3 |
Reconstituted Complex, Reconstituted Complex, Two-hybrid |
EMC2 |
YJR088C |
Member of conserved ER transmembrane complex |
genetic |
3 |
2 |
3 |
Synthetic Lethality, Synthetic Growth Defect, Synthetic Growth Defect |
BMH1 |
YER177W |
14-3-3 protein, major isoform |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
ACC1 |
YNR016C |
Acetyl-CoA carboxylase, biotin containing enzyme |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
ASC1 |
YMR116C |
G-protein beta subunit and guanine dissociation inhibitor for Gpa2p |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
CDC55 |
YGL190C |
Regulatory subunit B of protein phosphatase 2A (PP2A) |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
CPR1 |
YDR155C |
Cytoplasmic peptidyl-prolyl cis-trans isomerase (cyclophilin) |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
CYR1 |
YJL005W |
Adenylate cyclase |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
FPR1 |
YNL135C |
Peptidyl-prolyl cis-trans isomerase (PPIase) |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
DIG1 |
YPL049C |
MAP kinase-responsive inhibitor of the Ste12p transcription factor |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
SND3 |
YBR106W |
Involved in SRP-independent protein targeting to the ER |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
PGK1 |
YCR012W |
3-phosphoglycerate kinase |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
RVB1 |
YDR190C |
ATP-dependent DNA helicase, also known as pontin |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
LSM12 |
YHR121W |
Protein of unknown function that may function in RNA processing |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
MPP10 |
YJR002W |
Component of the SSU processome and 90S preribosome |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
SOF1 |
YLL011W |
Protein required for biogenesis of 40S (small) ribosomal subunit |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
RPN11 |
YFR004W |
Metalloprotease subunit of 19S regulatory particle |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
RPL10 |
YLR075W |
Ribosomal 60S subunit protein L10 |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
RPL8A |
YHL033C |
Ribosomal 60S subunit protein L8A |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
RPL28 |
YGL103W |
Ribosomal 60S subunit protein L28 |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
RPL16A |
YIL133C |
Ribosomal 60S subunit protein L16A |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
RPP0 |
YLR340W |
Conserved ribosomal protein P0 of the ribosomal stalk |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
RPL21A |
YBR191W |
Ribosomal 60S subunit protein L21A |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
PBP1 |
YGR178C |
Component of glucose deprivation induced stress granules |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
MSB1 |
YOR188W |
Protein of unknown function |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
RPP2B |
YDR382W |
Ribosomal protein P2 beta |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
YGR266W |
YGR266W |
Protein of unknown function |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
RPS4A |
YJR145C |
Protein component of the small (40S) ribosomal subunit |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
RTN1 |
YDR233C |
Reticulon protein |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
RPP2A |
YOL039W |
Ribosomal protein P2 alpha |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
RPL9A |
YGL147C |
Ribosomal 60S subunit protein L9A |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
HYP2 |
YEL034W |
Translation elongation factor eIF-5A |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
PMA1 |
YGL008C |
Plasma membrane P2-type H+-ATPase |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
NMA1 |
YLR328W |
Nicotinic acid mononucleotide adenylyltransferase |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
UTP11 |
YKL099C |
Subunit of U3-containing Small Subunit (SSU) processome complex |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
PAL2 |
YHR097C |
Protein involved in clathrin-mediated endocytosis |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
RPS29A |
YLR388W |
Protein component of the small (40S) ribosomal subunit |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
RPS29B |
YDL061C |
Protein component of the small (40S) ribosomal subunit |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
RPL4A |
YBR031W |
Ribosomal 60S subunit protein L4A |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
NPL3 |
YDR432W |
RNA-binding protein |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
RPL11A |
YPR102C |
Ribosomal 60S subunit protein L11A |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
PWP1 |
YLR196W |
Protein with WD-40 repeats involved in rRNA processing |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
RPL26A |
YLR344W |
Ribosomal 60S subunit protein L26A |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
RPS15 |
YOL040C |
Protein component of the small (40S) ribosomal subunit |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
RPS17A |
YML024W |
Ribosomal protein 51 (rp51) of the small (40s) subunit |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
RPS1B |
YML063W |
Ribosomal protein of the small (40S) subunit |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
RPL29 |
YFR032C-A |
Ribosomal 60S subunit protein L29 |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
PAL1 |
YDR348C |
Protein of unknown function thought to be involved in endocytosis |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
TEF1 |
YPR080W |
Translational elongation factor EF-1 alpha |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
IST2 |
YBR086C |
Cortical ER protein involved in ER-plasma membrane (PM) tethering |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
RPL19A |
YBR084C-A |
Ribosomal 60S subunit protein L19A |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
PSP2 |
YML017W |
Asn rich cytoplasmic protein that contains RGG motifs |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
RPL13B |
YMR142C |
Ribosomal 60S subunit protein L13B |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
LEU4 |
YNL104C |
Alpha-isopropylmalate synthase (2-isopropylmalate synthase) |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
SGN1 |
YIR001C |
Cytoplasmic RNA-binding protein |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
TIF34 |
YMR146C |
eIF3i subunit of the eukaryotic translation initiation factor 3 (eIF3) |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
MRPL32 |
YCR003W |
Mitochondrial ribosomal protein of the large subunit |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
SEC13 |
YLR208W |
Structural component of 3 complexes |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
RPS19A |
YOL121C |
Protein component of the small (40S) ribosomal subunit |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
RPL2A |
YFR031C-A |
Ribosomal 60S subunit protein L2A |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
ILV6 |
YCL009C |
Regulatory subunit of acetolactate synthase |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
TES1 |
YJR019C |
Peroxisomal acyl-CoA thioesterase |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
TDH1 |
YJL052W |
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 1 |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
SEC53 |
YFL045C |
Phosphomannomutase |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
SSD1 |
YDR293C |
Translational repressor |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
MSN4 |
YKL062W |
Stress-responsive transcriptional activator |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
PRB1 |
YEL060C |
Vacuolar proteinase B (yscB) with H3 N-terminal endopeptidase activity |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
RSP5 |
YER125W |
NEDD4 family E3 ubiquitin ligase |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
RGI1 |
YER067W |
Protein involved in energy metabolism under respiratory conditions |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
URA2 |
YJL130C |
Bifunctional carbamoylphosphate synthetase/aspartate transcarbamylase |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
DOT6 |
YER088C |
Protein involved in rRNA and ribosome biogenesis |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
ATP2 |
YJR121W |
Beta subunit of the F1 sector of mitochondrial F1F0 ATP synthase |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
FPR3 |
YML074C |
Nucleolar peptidyl-prolyl cis-trans isomerase (PPIase) |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
AKL1 |
YBR059C |
Ser/Thr protein kinase |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
ACS2 |
YLR153C |
Acetyl-coA synthetase isoform |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
CYS3 |
YAL012W |
Cystathionine gamma-lyase |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
CUE5 |
YOR042W |
Ubiquitin-binding protein |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
BRE5 |
YNR051C |
Ubiquitin protease cofactor |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
ABF1 |
YKL112W |
DNA binding protein with possible chromatin-reorganizing activity |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
GTS1 |
YGL181W |
Protein involved in Arf3p regulation and in transcription regulation |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
HBT1 |
YDL223C |
Shmoo tip protein, substrate of Hub1p ubiquitin-like protein |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
EFT1 |
YOR133W |
Elongation factor 2 (EF-2), also encoded by EFT2 |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
PAT1 |
YCR077C |
Deadenylation-dependent mRNA-decapping factor |
physical |
3 |
3 |
2 |
Two-hybrid, Affinity Capture-MS, Affinity Capture-RNA |
RAD51 |
YER095W |
Strand exchange protein |
genetic |
3 |
3 |
2 |
Synthetic Growth Defect, Dosage Rescue, Phenotypic Suppression |
GCN2 |
YDR283C |
Protein kinase |
physical |
3 |
2 |
2 |
Affinity Capture-Western, Affinity Capture-Western, Two-hybrid |
PIH1 |
YHR034C |
Component of the conserved R2TP complex (Rvb1-Rvb2-Tah1-Pih1) |
physical |
3 |
2 |
2 |
Two-hybrid, Two-hybrid, Affinity Capture-Western |
CHL1 |
YPL008W |
Probable DNA helicase |
physical |
3 |
2 |
2 |
Two-hybrid, Two-hybrid, Affinity Capture-Western |
CPR7 |
YJR032W |
Peptidyl-prolyl cis-trans isomerase (cyclophilin) |
genetic |
3 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect, Synthetic Lethality |
ADE1 |
YAR015W |
N-succinyl-5-aminoimidazole-4-carboxamide ribotide synthetase |
physical |
3 |
2 |
2 |
Two-hybrid, Affinity Capture-MS, Affinity Capture-MS |
GLN1 |
YPR035W |
Glutamine synthetase (GS) |
physical |
3 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
MSN2 |
YMR037C |
Stress-responsive transcriptional activator |
regulation |
2 |
2 |
2 |
chromatin immunoprecipitation-chip evidence, RNA-sequencing evidence |
CKA2 |
YOR061W |
Alpha' catalytic subunit of casein kinase 2 (CK2) |
genetic |
2 |
2 |
2 |
Dosage Rescue, Synthetic Growth Defect |
CCT4 |
YDL143W |
Subunit of the cytosolic chaperonin Cct ring complex |
physical |
2 |
2 |
2 |
Two-hybrid, Affinity Capture-MS |
COG8 |
YML071C |
Component of the conserved oligomeric Golgi complex |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
AHA1 |
YDR214W |
Co-chaperone that binds Hsp82p and activates its ATPase activity |
genetic |
2 |
2 |
2 |
Phenotypic Suppression, Dosage Rescue |
HSP42 |
YDR171W |
Small heat shock protein (sHSP) with chaperone activity |
physical |
2 |
2 |
2 |
Two-hybrid, Affinity Capture-MS |
SKP1 |
YDR328C |
Evolutionarily conserved kinetochore protein |
physical |
2 |
2 |
2 |
Affinity Capture-Western, Affinity Capture-MS |
YDJ1 |
YNL064C |
Type I HSP40 co-chaperone |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
SGT1 |
YOR057W |
Cochaperone protein |
genetic |
2 |
2 |
2 |
Dosage Rescue, Synthetic Growth Defect |
PRO1 |
YDR300C |
Gamma-glutamyl kinase |
physical |
2 |
2 |
2 |
Two-hybrid, Affinity Capture-MS |
MED7 |
YOL135C |
Subunit of the RNA polymerase II mediator complex |
genetic |
2 |
2 |
2 |
Synthetic Rescue, Synthetic Growth Defect |
YDL199C |
YDL199C |
Putative transporter |
physical |
2 |
2 |
2 |
Affinity Capture-MS, Two-hybrid |
HXT10 |
YFL011W |
Hexose transporter |
physical |
2 |
2 |
2 |
Affinity Capture-MS, Two-hybrid |
MCK1 |
YNL307C |
Dual-specificity ser/thr and tyrosine protein kinase |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
MOG1 |
YJR074W |
Conserved nuclear protein that interacts with GTP-Gsp1p |
physical |
2 |
2 |
2 |
Two-hybrid, Affinity Capture-MS |
YPT7 |
YML001W |
Rab family GTPase |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
HTS1 |
YPR033C |
Cytoplasmic and mitochondrial histidine tRNA synthetase |
physical |
2 |
2 |
2 |
Two-hybrid, Affinity Capture-MS |
LYS21 |
YDL131W |
Homocitrate synthase isozyme |
physical |
2 |
2 |
2 |
Two-hybrid, Affinity Capture-MS |
URE2 |
YNL229C |
Nitrogen catabolite repression transcriptional regulator |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
SWE1 |
YJL187C |
Protein kinase that regulates the G2/M transition |
physical |
2 |
2 |
2 |
Biochemical Activity, Affinity Capture-Western |
SSE2 |
YBR169C |
Member of Hsp110 subclass of the heat shock protein 70 (HSP70) family |
physical |
2 |
2 |
2 |
Affinity Capture-Western, Affinity Capture-MS |
SBP1 |
YHL034C |
Protein that binds eIF4G and has a role in repression of translation |
physical |
2 |
2 |
2 |
Affinity Capture-RNA, Affinity Capture-MS |
NPL3 |
YDR432W |
RNA-binding protein |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Synthetic Rescue |
RPL13B |
YMR142C |
Ribosomal 60S subunit protein L13B |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
SSC1 |
YJR045C |
Hsp70 family ATPase |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Phenotypic Suppression |
UBP3 |
YER151C |
Ubiquitin-specific protease that cleaves Ub-protein fusions |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
SAC1 |
YKL212W |
Phosphatidylinositol phosphate phosphatase |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
SAM1 |
YLR180W |
S-adenosylmethionine synthetase |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
SEC28 |
YIL076W |
Epsilon-COP subunit of the coatomer |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
SSA4 |
YER103W |
Heat shock protein that is highly induced upon stress |
physical |
2 |
2 |
2 |
Affinity Capture-MS, Reconstituted Complex |
UBP6 |
YFR010W |
Ubiquitin-specific protease |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
YPK1 |
YKL126W |
S/T protein kinase |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
MTC1 |
YJL123C |
Protein of unknown function that may interact with ribosomes |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
LTE1 |
YAL024C |
Protein similar to GDP/GTP exchange factors |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
LDB7 |
YBL006C |
Component of the RSC chromatin remodeling complex |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
SAF1 |
YBR280C |
F-Box protein involved in proteasome-dependent degradation of Aah1p |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
PER1 |
YCR044C |
Protein of the endoplasmic reticulum |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
VAM6 |
YDL077C |
Guanine nucleotide exchange factor for the GTPase Gtr1p |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
PMP3 |
YDR276C |
Small plasma membrane protein |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
SUM1 |
YDR310C |
Transcriptional repressor that regulates middle-sporulation genes |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
SPT3 |
YDR392W |
Subunit of the SAGA and SAGA-like transcriptional regulatory complexes |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
SSN2 |
YDR443C |
Subunit of the RNA polymerase II mediator complex |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
TCA17 |
YEL048C |
Component of transport protein particle (TRAPP) complex II |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
MAK10 |
YEL053C |
Non-catalytic subunit of the NatC N-terminal acetyltransferase |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
VAM7 |
YGL212W |
Vacuolar SNARE protein |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
ZRT1 |
YGL255W |
High-affinity zinc transporter of the plasma membrane |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Negative Genetic |
SPT4 |
YGR063C |
Spt4p/5p (DSIF) transcription elongation factor complex subunit |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
LRP1 |
YHR081W |
Nuclear exosome-associated nucleic acid binding protein |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
YIA6 |
YIL006W |
Mitochondrial NAD+ transporter |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
RPL34B |
YIL052C |
Ribosomal 60S subunit protein L34B |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
SOA1 |
YIL166C |
Sulfonate and inorganic sulfur transporter |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
MAD2 |
YJL030W |
Component of the spindle-assembly checkpoint complex |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
YJR056C |
YJR056C |
Protein of unknown function |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
OPI3 |
YJR073C |
Methylene-fatty-acyl-phospholipid synthase |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
XDJ1 |
YLR090W |
Chaperone with a role in facilitating mitochondrial protein import |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
ICT1 |
YLR099C |
Lysophosphatidic acid acyltransferase |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
SRN2 |
YLR119W |
Component of the ESCRT-I complex |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
SKI2 |
YLR398C |
Ski complex component and putative RNA helicase |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
SNO1 |
YMR095C |
Protein of unconfirmed function |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
RIM13 |
YMR154C |
Calpain-like cysteine protease |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
SCJ1 |
YMR214W |
One of several homologs of bacterial chaperone DnaJ |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
SIW14 |
YNL032W |
Inositol phosphatase involved in inositol pyrophosphate metabolism |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
YNL058C |
YNL058C |
Putative protein of unknown function |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
RAS2 |
YNL098C |
GTP-binding protein |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
MET22 |
YOL064C |
Bisphosphate-3'-nucleotidase |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
IRA2 |
YOL081W |
GTPase-activating protein |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Positive Genetic |
MDY2 |
YOL111C |
Protein involved in inserting tail-anchored proteins into ER membranes |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
RUD3 |
YOR216C |
Golgi matrix protein |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
SNF2 |
YOR290C |
Catalytic subunit of the SWI/SNF chromatin remodeling complex |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
SNC2 |
YOR327C |
Vesicle membrane receptor protein (v-SNARE) |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
YME1 |
YPR024W |
Catalytic subunit of i-AAA protease complex |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Rescue |
MCM16 |
YPR046W |
Component of the Ctf19 complex and the COMA subcomplex |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
SIN4 |
YNL236W |
Subunit of the RNA polymerase II mediator complex |
genetic |
2 |
2 |
2 |
Synthetic Rescue, Synthetic Growth Defect |
SRB7 |
YDR308C |
Subunit of the RNA polymerase II mediator complex |
genetic |
2 |
2 |
2 |
Synthetic Rescue, Synthetic Growth Defect |
KIN28 |
YDL108W |
Ser/Thr protein kinase and subunit of TFIIK, a TFIIH subassembly |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
LHS1 |
YKL073W |
Molecular chaperone of the endoplasmic reticulum lumen |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Phenotypic Suppression |
CCT8 |
YJL008C |
Subunit of the cytosolic chaperonin Cct ring complex |
physical |
2 |
2 |
2 |
Two-hybrid, Affinity Capture-MS |
CAM1 |
YPL048W |
One of two isoforms of the gamma subunit of eEF1B |
physical |
2 |
2 |
2 |
Two-hybrid, Affinity Capture-MS |
CAR2 |
YLR438W |
L-ornithine transaminase (OTAse) |
physical |
2 |
2 |
2 |
Two-hybrid, Affinity Capture-MS |
GPP1 |
YIL053W |
Constitutively expressed DL-glycerol-3-phosphate phosphatase |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
ARF1 |
YDL192W |
ADP-ribosylation factor |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
CMP2 |
YML057W |
Calcineurin A |
physical |
2 |
2 |
2 |
Affinity Capture-Western, Affinity Capture-MS |
DPS1 |
YLL018C |
Aspartyl-tRNA synthetase, primarily cytoplasmic |
physical |
2 |
2 |
2 |
Two-hybrid, Affinity Capture-MS |
GLC8 |
YMR311C |
Regulatory subunit of protein phosphatase 1 (Glc7p) |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
HSP104 |
YLL026W |
Disaggregase |
genetic |
2 |
2 |
2 |
Phenotypic Suppression, Phenotypic Enhancement |
FRS2 |
YFL022C |
Alpha subunit of cytoplasmic phenylalanyl-tRNA synthetase |
physical |
2 |
2 |
2 |
Two-hybrid, Affinity Capture-MS |
HOG1 |
YLR113W |
Mitogen-activated protein kinase involved in osmoregulation |
physical |
2 |
2 |
2 |
Two-hybrid, Affinity Capture-MS |
BEM4 |
YPL161C |
Protein involved in establishment of cell polarity and bud emergence |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
AVT2 |
YEL064C |
Putative transporter |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
FIS1 |
YIL065C |
Protein involved in mitochondrial fission and peroxisome abundance |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
CDC26 |
YFR036W |
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
COG6 |
YNL041C |
Component of the conserved oligomeric Golgi complex |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
BRE5 |
YNR051C |
Ubiquitin protease cofactor |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
GIM4 |
YEL003W |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
FIG4 |
YNL325C |
Phosphatidylinositol 3,5-bisphosphate (PtdIns[3,5]P) phosphatase |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
ATP10 |
YLR393W |
Assembly factor for the F0 sector of mitochondrial F1F0 ATP synthase |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
ATP1 |
YBL099W |
Alpha subunit of the F1 sector of mitochondrial F1F0 ATP synthase |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Synthetic Rescue |
DID2 |
YKR035W-A |
Class E protein of the vacuolar protein-sorting (Vps) pathway |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
CPS1 |
YJL172W |
Vacuolar carboxypeptidase S |
physical |
2 |
2 |
2 |
Two-hybrid, Affinity Capture-MS |
FMP23 |
YBR047W |
Putative protein of unknown function |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
AQY3 |
YFL054C |
Putative channel-like protein |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
AIM26 |
YKL037W |
Protein of unknown function |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
GIS2 |
YNL255C |
Translational activator for mRNAs with internal ribosome entry sites |
physical |
2 |
2 |
2 |
Affinity Capture-RNA, Affinity Capture-MS |
ALT1 |
YLR089C |
Alanine transaminase (glutamic pyruvic transaminase) |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
GGC1 |
YDL198C |
Mitochondrial GTP/GDP transporter |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
AIM36 |
YMR157C |
Protein of unknown function |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
ATP23 |
YNR020C |
Putative metalloprotease of the mitochondrial inner membrane |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
CBF5 |
YLR175W |
Pseudouridine synthase catalytic subunit of box H/ACA snoRNPs |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
CDC33 |
YOL139C |
Translation initiation factor eIF4E |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
CDC48 |
YDL126C |
AAA ATPase with protein-unfoldase activity |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
GCD11 |
YER025W |
Gamma subunit of the translation initiation factor eIF2 |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
ALA1 |
YOR335C |
Cytoplasmic and mitochondrial alanyl-tRNA synthetase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
EFT2 |
YDR385W |
Elongation factor 2 (EF-2), also encoded by EFT1 |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
APL2 |
YKL135C |
Beta-adaptin subunit of the clathrin-associated protein (AP-1) complex |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
ARO1 |
YDR127W |
Pentafunctional arom protein |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
BMH2 |
YDR099W |
14-3-3 protein, minor isoform |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
BEM2 |
YER155C |
Rho GTPase activating protein (RhoGAP) |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
CDC28 |
YBR160W |
Cyclin-dependent kinase (CDK) catalytic subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
CYS4 |
YGR155W |
Cystathionine beta-synthase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
HRP1 |
YOL123W |
Subunit of cleavage factor I |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
CLU1 |
YMR012W |
Subunit of the eukaryotic translation initiation factor 3 (eIF3) |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
ECM29 |
YHL030W |
Scaffold protein |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
ENO2 |
YHR174W |
Enolase II, a phosphopyruvate hydratase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
SHE3 |
YBR130C |
Protein adaptor between Myo4p and the She2p-mRNA complex |
physical |
2 |
1 |
2 |
Two-hybrid, Two-hybrid |
RPL6A |
YML073C |
Ribosomal 60S subunit protein L6A |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
RTK1 |
YDL025C |
Putative protein kinase, potentially phosphorylated by Cdc28p |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
UFD2 |
YDL190C |
Ubiquitin (Ub) chain assembly factor (E4) |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
NTH1 |
YDR001C |
Neutral trehalase, degrades trehalose |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
TOM1 |
YDR457W |
E3 ubiquitin ligase of the hect-domain class |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
MET6 |
YER091C |
Cobalamin-independent methionine synthase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
SPT15 |
YER148W |
TATA-binding protein (TBP) |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
LEU1 |
YGL009C |
Isopropylmalate isomerase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
SEC27 |
YGL137W |
Essential beta'-coat protein of the COPI coatomer |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
RPN1 |
YHR027C |
Non-ATPase base subunit of the 19S RP of the 26S proteasome |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
NCP1 |
YHR042W |
NADP-cytochrome P450 reductase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
RPL40A |
YIL148W |
Ubiquitin-ribosomal 60S subunit protein L40A fusion protein |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
SRP1 |
YNL189W |
Karyopherin alpha homolog |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
MCK1 |
YNL307C |
Dual-specificity ser/thr and tyrosine protein kinase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
SHE4 |
YOR035C |
Protein containing a UCS (UNC-45/CRO1/SHE4) domain |
physical |
2 |
1 |
2 |
Two-hybrid, Two-hybrid |
LYS12 |
YIL094C |
Homo-isocitrate dehydrogenase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
TPK1 |
YJL164C |
cAMP-dependent protein kinase catalytic subunit |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
RPN10 |
YHR200W |
Proteasome polyubiquitin receptor |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
RPT5 |
YOR117W |
ATPase of the 19S regulatory particle of the 26S proteasome |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
NPA3 |
YJR072C |
Member of the conserved GPN-loop GTPase family |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
RAD51 |
YER095W |
Strand exchange protein |
physical |
2 |
1 |
2 |
Affinity Capture-Western, Affinity Capture-Western |
TRX2 |
YGR209C |
Cytoplasmic thioredoxin isoenzyme |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
MOT2 |
YER068W |
Ubiquitin-protein ligase subunit of the CCR4-NOT complex |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
MSC3 |
YLR219W |
Protein of unknown function |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
REG1 |
YDR028C |
Regulatory subunit of type 1 protein phosphatase Glc7p |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
RPL12A |
YEL054C |
Ribosomal 60S subunit protein L12A |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
RPL20A |
YMR242C |
Ribosomal 60S subunit protein L20A |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
RPL20A |
YMR242C |
Ribosomal 60S subunit protein L20A |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
RRT14 |
YIL127C |
Putative protein of unknown function |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
RSA1 |
YPL193W |
Protein involved in the assembly of 60S ribosomal subunits |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
NSR1 |
YGR159C |
Nucleolin, nucleolar protein that binds nuclear localization sequences |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
RPP2B |
YDR382W |
Ribosomal protein P2 beta |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
RPL1A |
YPL220W |
Ribosomal 60S subunit protein L1A |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
NGR1 |
YBR212W |
RNA binding protein that negatively regulates growth rate |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
RPL16B |
YNL069C |
Ribosomal 60S subunit protein L16B |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
RPL32 |
YBL092W |
Ribosomal 60S subunit protein L32 |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
RPL17A |
YKL180W |
Ribosomal 60S subunit protein L17A |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
NOP13 |
YNL175C |
Nucleolar protein found in preribosomal complexes |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
RPS21A |
YKR057W |
Protein component of the small (40S) ribosomal subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
RPL37A |
YLR185W |
Ribosomal 60S subunit protein L37A |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
KRI1 |
YNL308C |
Essential nucleolar protein required for 40S ribosome biogenesis |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
RPS14B |
YJL191W |
Protein component of the small (40S) ribosomal subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
MSN2 |
YMR037C |
Stress-responsive transcriptional activator |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
YRA2 |
YKL214C |
Member of the REF (RNA and export factor binding proteins) family |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
RPS26A |
YGL189C |
Protein component of the small (40S) ribosomal subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
TEF2 |
YBR118W |
Translational elongation factor EF-1 alpha |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
RPL27A |
YHR010W |
Ribosomal 60S subunit protein L27A |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
PHO23 |
YNL097C |
Component of the Rpd3L histone deacetylase complex |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
YLR227W-B |
YLR227W-B |
Retrotransposon TYA Gag and TYB Pol genes |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
YDR365W-B |
YDR365W-B |
Retrotransposon TYA Gag and TYB Pol genes |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
PNC1 |
YGL037C |
Nicotinamidase that converts nicotinamide to nicotinic acid |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
ZIM17 |
YNL310C |
Protein co-chaperone with a zinc finger motif |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
YLR410W-B |
YLR410W-B |
Retrotransposon TYA Gag and TYB Pol genes |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
SHM2 |
YLR058C |
Cytosolic serine hydroxymethyltransferase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
TIF35 |
YDR429C |
eIF3g subunit of the eukaryotic translation initiation factor 3 (eIF3) |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
LYS20 |
YDL182W |
Homocitrate synthase isozyme and functions in DNA repair |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
YDR210C-D |
YDR210C-D |
Retrotransposon TYA Gag and TYB Pol genes |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
RPL30 |
YGL030W |
Ribosomal 60S subunit protein L30 |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
KRS1 |
YDR037W |
Lysyl-tRNA synthetase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
SDH2 |
YLL041C |
Iron-sulfur protein subunit of succinate dehydrogenase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
VMA1 |
YDL185W |
Subunit A of the V1 peripheral membrane domain of V-ATPase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
RPS10B |
YMR230W |
Protein component of the small (40S) ribosomal subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
TPS1 |
YBR126C |
Synthase subunit of trehalose-6-P synthase/phosphatase complex |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
RPC40 |
YPR110C |
RNA polymerase subunit AC40 |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
RPS8A |
YBL072C |
Protein component of the small (40S) ribosomal subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
ILV2 |
YMR108W |
Acetolactate synthase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
YEF3 |
YLR249W |
Translation elongation factor 3 |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
PDC1 |
YLR044C |
Major of three pyruvate decarboxylase isozymes |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
PET9 |
YBL030C |
Major ADP/ATP carrier of the mitochondrial inner membrane |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
RPS1A |
YLR441C |
Ribosomal protein of the small (40S) subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
RPL23A |
YBL087C |
Ribosomal 60S subunit protein L23A |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
SAR1 |
YPL218W |
ARF family GTPase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
TIF1 |
YKR059W |
Translation initiation factor eIF4A |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
POR1 |
YNL055C |
Mitochondrial porin (voltage-dependent anion channel) |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
SCS2 |
YER120W |
Integral ER membrane protein, regulates phospholipid metabolism |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
IPP1 |
YBR011C |
Cytoplasmic inorganic pyrophosphatase (PPase) |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
SRV2 |
YNL138W |
CAP (cyclase-associated protein) |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
RPP1B |
YDL130W |
Ribosomal protein P1 beta |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
SCP160 |
YJL080C |
Essential RNA-binding G protein effector of mating response pathway |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
TEF4 |
YKL081W |
Gamma subunit of translational elongation factor eEF1B |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
THS1 |
YIL078W |
Threonyl-tRNA synthetase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
VAS1 |
YGR094W |
Mitochondrial and cytoplasmic valyl-tRNA synthetase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
YHB1 |
YGR234W |
Nitric oxide oxidoreductase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
IDH1 |
YNL037C |
Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
PUB1 |
YNL016W |
Poly (A)+ RNA-binding protein |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
RPS12 |
YOR369C |
Protein component of the small (40S) ribosomal subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
RPS14A |
YCR031C |
Protein component of the small (40S) ribosomal subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
SIS1 |
YNL007C |
Type II HSP40 co-chaperone that interacts with the HSP70 protein Ssa1p |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
VAC8 |
YEL013W |
Vacuole-specific Myo2p receptor |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
SGT2 |
YOR007C |
Glutamine-rich cytoplasmic cochaperone |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
VPS8 |
YAL002W |
Membrane-binding component of the CORVET complex |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
YBR016W |
YBR016W |
Tail-anchored plasma membrane protein with a conserved CYSTM module |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
RFS1 |
YBR052C |
Protein of unknown function |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
MAL31 |
YBR298C |
Maltose permease |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
RBK1 |
YCR036W |
Ribokinase, phosphorylates ribose to ribose-5-phosphate |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
TUP1 |
YCR084C |
General repressor of transcription in complex with Cyc8p |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
RPL13A |
YDL082W |
Ribosomal 60S subunit protein L13A |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
SNF11 |
YDR073W |
Subunit of the SWI/SNF chromatin remodeling complex |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
TRS23 |
YDR246W |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
RKM4 |
YDR257C |
Ribosomal lysine methyltransferase |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
RAD34 |
YDR314C |
Protein involved in nucleotide excision repair (NER) |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
MSN5 |
YDR335W |
Karyopherin |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
URH1 |
YDR400W |
Uridine nucleosidase (uridine-cytidine N-ribohydrolase) |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
PAC2 |
YER007W |
Microtubule effector required for tubulin heterodimer formation |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
OTU1 |
YFL044C |
Deubiquitylation enzyme that binds to the chaperone-ATPase Cdc48p |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
MRF1 |
YGL143C |
Mitochondrial translation release factor |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
RPL24B |
YGR148C |
Ribosomal 60S subunit protein L24B |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
PTC7 |
YHR076W |
Type 2C serine/threonine protein phosphatase (PP2C) |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
STE12 |
YHR084W |
Transcription factor that is activated by a MAPK signaling cascade |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
RAM2 |
YKL019W |
Alpha subunit of farnesyltransferase and geranylgeranyltransferase-I |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
PAN3 |
YKL025C |
Essential subunit of the Pan2p-Pan3p poly(A)-ribonuclease complex |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
SLD2 |
YKL108W |
Single-stranded DNA origin-binding and annealing protein |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
IRS4 |
YKR019C |
EH domain-containing protein |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
PAU17 |
YLL025W |
Protein of unknown function |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
VPS13 |
YLL040C |
Lipid transport protein involved in prospore membrane morphogenesis |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
SSK1 |
YLR006C |
Cytoplasmic phosphorelay intermediate osmosensor and regulator |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
TUB1 |
YML085C |
Alpha-tubulin |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
VPS9 |
YML097C |
Guanine nucleotide exchange factor (GEF) and ubiquitin receptor |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
MGL2 |
YMR210W |
Monoacylglycerol and triacylglycerol lipase |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
RPS19B |
YNL302C |
Protein component of the small (40S) ribosomal subunit |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
SMM1 |
YNR015W |
Dihydrouridine synthase |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
MAM3 |
YOL060C |
Protein involved in magnesium homeostasis |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
PAP2 |
YOL115W |
Non-canonical poly(A) polymerase |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
SFL1 |
YOR140W |
Transcriptional repressor and activator |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
PDR5 |
YOR153W |
Plasma membrane ATP-binding cassette (ABC) transporter |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
RPL33B |
YOR234C |
Ribosomal 60S subunit protein L33B |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
MUM3 |
YOR298W |
Protein of unknown function involved in outer spore wall organization |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
YOR342C |
YOR342C |
Protein of unknown function |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
YPL068C |
YPL068C |
Protein of unknown function |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
MGR2 |
YPL098C |
Subunit of the TIM23 translocase complex |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
ADE57 |
YGL234W |
Bifunctional enzyme of 'de novo' purine nucleotide pathway |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
CCT6 |
YDR188W |
Subunit of the cytosolic chaperonin Cct ring complex |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
ATP4 |
YPL078C |
Subunit b of the stator stalk of mitochondrial F1F0 ATP synthase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
ACO1 |
YLR304C |
Aconitase |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
ATP3 |
YBR039W |
Gamma subunit of the F1 sector of mitochondrial F1F0 ATP synthase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
CAF20 |
YOR276W |
Phosphoprotein of the mRNA cap-binding complex |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
FOL2 |
YGR267C |
GTP-cyclohydrolase I, catalyzes first step in folic acid biosynthesis |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
CPR6 |
YLR216C |
Peptidyl-prolyl cis-trans isomerase (cyclophilin) |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
DIG2 |
YDR480W |
MAP kinase-responsive inhibitor of the Ste12p transcription factor |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
CDC20 |
YGL116W |
Activator of anaphase-promoting complex/cyclosome (APC/C) |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
EMI2 |
YDR516C |
Hexokinase expressed during growth with low glucose levels |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
DUF1 |
YOL087C |
Ubiquitin-binding protein of unknown function |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
GCY1 |
YOR120W |
Glycerol dehydrogenase |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
DID4 |
YKL002W |
Class E Vps protein of the ESCRT-III complex |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
ADE2 |
YOR128C |
Phosphoribosylaminoimidazole carboxylase |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
ADE8 |
YDR408C |
Phosphoribosyl-glycinamide transformylase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
BNI4 |
YNL233W |
Targeting subunit for Glc7p protein phosphatase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
HRB1 |
YNL004W |
Poly(A+) RNA-binding protein |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
ATC1 |
YDR184C |
Nuclear protein |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
ATP1 |
YBL099W |
Alpha subunit of the F1 sector of mitochondrial F1F0 ATP synthase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
BSD2 |
YBR290W |
Heavy metal ion homeostasis protein |
physical |
2 |
1 |
2 |
Two-hybrid, Two-hybrid |
ARR3 |
YPR201W |
Plasma membrane metalloid/H+ antiporter |
physical |
2 |
1 |
2 |
Two-hybrid, Two-hybrid |
FRA1 |
YLL029W |
Protein involved in negative regulation of iron regulon transcription |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
CSF1 |
YLR087C |
Protein with structural similarity to lipid transport protein Vps13p |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
BDH1 |
YAL060W |
NAD-dependent (R,R)-butanediol dehydrogenase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
ATP12 |
YJL180C |
Assembly factor for F1 sector of mitochondrial F1F0 ATP synthase |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
COQ6 |
YGR255C |
Flavin-dependent monooxygenase involved in ubiquinone biosynthesis |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
EGH1 |
YIR007W |
Steryl-beta-glucosidase with broad specificity for aglycones |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
GUA1 |
YMR217W |
GMP synthase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
DIA1 |
YMR316W |
Protein of unknown function |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
GIS1 |
YDR096W |
Histone demethylase and transcription factor |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
GIS1 |
YDR096W |
Histone demethylase and transcription factor |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
HIT1 |
YJR055W |
Protein involved in C/D snoRNP assembly |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
FIT3 |
YOR383C |
Mannoprotein that is incorporated into the cell wall |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
HIS7 |
YBR248C |
Imidazole glycerol phosphate synthase |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
CCC2 |
YDR270W |
Cu(+2)-transporting P-type ATPase |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
AGC1 |
YPR021C |
Mitochondrial amino acid transporter |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
CAB2 |
YIL083C |
Phosphopantothenoylcysteine synthetase (PPCS) |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
ECM14 |
YHR132C |
Conserved fungal protein with similarity to zinc carboxypeptidases |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
BET3 |
YKR068C |
Core component of transport protein particle (TRAPP) complexes I-III |
physical |
2 |
2 |
1 |
Two-hybrid, Affinity Capture-MS |
CDC14 |
YFR028C |
Protein phosphatase required for mitotic exit |
physical |
2 |
2 |
1 |
Affinity Capture-Western, Affinity Capture-MS |
SSL2 |
YIL143C |
Component of RNA polymerase transcription factor TFIIH holoenzyme |
physical |
2 |
2 |
1 |
Reconstituted Complex, Affinity Capture-Western |
MPS1 |
YDL028C |
Dual-specificity kinase |
physical |
2 |
2 |
1 |
Biochemical Activity, Affinity Capture-Western |
RAD53 |
YPL153C |
DNA damage response kinase |
genetic |
2 |
2 |
1 |
Phenotypic Suppression, Dosage Rescue |
BNI4 |
YNL233W |
Targeting subunit for Glc7p protein phosphatase |
physical |
2 |
2 |
1 |
Two-hybrid, Affinity Capture-MS |
HSP31 |
YDR533C |
Methylglyoxalase that converts methylglyoxal to D-lactate |
physical |
2 |
2 |
1 |
Two-hybrid, Affinity Capture-MS |
FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RIM101 |
YHL027W |
Cys2His2 zinc-finger transcriptional repressor |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
SFP1 |
YLR403W |
Regulates transcription of ribosomal protein and biogenesis genes |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
GCN5 |
YGR252W |
Catalytic subunit of ADA and SAGA histone acetyltransferase complexes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
FKH2 |
YNL068C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
MED2 |
YDL005C |
Subunit of the RNA polymerase II mediator complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RGR1 |
YLR071C |
Subunit of the RNA polymerase II mediator complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
XBP1 |
YIL101C |
Transcriptional repressor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
BUR6 |
YER159C |
Subunit of a heterodimeric NC2 transcription regulator complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
STP1 |
YDR463W |
Transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
YAP6 |
YDR259C |
Basic leucine zipper (bZIP) transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SIN4 |
YNL236W |
Subunit of the RNA polymerase II mediator complex |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
TFC7 |
YOR110W |
RNA pol III transcription initiation factor complex (TFIIIC) subunit |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
STB1 |
YNL309W |
Protein with role in regulation of MBF-specific transcription at Start |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
SUA7 |
YPR086W |
Transcription factor TFIIB |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
MSN4 |
YKL062W |
Stress-responsive transcriptional activator |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
SPT3 |
YDR392W |
Subunit of the SAGA and SAGA-like transcriptional regulatory complexes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SPT7 |
YBR081C |
Subunit of the SAGA transcriptional regulatory complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
BAS1 |
YKR099W |
Myb-related transcription factor |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
SPT6 |
YGR116W |
Nucleosome remodeling protein |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
UME6 |
YDR207C |
Rpd3L histone deacetylase complex subunit |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
CST6 |
YIL036W |
Basic leucine zipper (bZIP) transcription factor from ATF/CREB family |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
PAF1 |
YBR279W |
Component of the Paf1p complex involved in transcription elongation |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
ADA2 |
YDR448W |
Transcription coactivator |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
NCB2 |
YDR397C |
Subunit of a heterodimeric NC2 transcription regulator complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SRB5 |
YGR104C |
Subunit of the RNA polymerase II mediator complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
PHO2 |
YDL106C |
Homeobox transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
AFT1 |
YGL071W |
Transcription factor involved in iron utilization and homeostasis |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
GTS1 |
YGL181W |
Protein involved in Arf3p regulation and in transcription regulation |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
NHP6A |
YPR052C |
High-mobility group (HMG) protein |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
AHA1 |
YDR214W |
Co-chaperone that binds Hsp82p and activates its ATPase activity |
regulation |
1 |
1 |
1 |
quantitative western immunoblotting evidence |
HCH1 |
YNL281W |
Heat shock protein regulator |
regulation |
1 |
1 |
1 |
quantitative western immunoblotting evidence |
CHD1 |
YER164W |
Chromatin remodeler that regulates various aspects of transcription |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CLF1 |
YLR117C |
Member of the NineTeen Complex (NTC) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CWC2 |
YDL209C |
Member of the NineTeen Complex (NTC) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CWC25 |
YNL245C |
Splicing factor required for the first step of pre-mRNA splicing |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CHL4 |
YDR254W |
Outer kinetochore protein required for chromosome stability |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
DED81 |
YHR019C |
Cytosolic asparaginyl-tRNA synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GWT1 |
YJL091C |
Protein involved in the inositol acylation of GlcN-PI |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CKA1 |
YIL035C |
Alpha catalytic subunit of casein kinase 2 (CK2) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CKB1 |
YGL019W |
Beta regulatory subunit of casein kinase 2 (CK2) |
physical |
1 |
1 |
1 |
Two-hybrid |
EAF1 |
YDR359C |
Component of the NuA4 histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
HSP60 |
YLR259C |
Tetradecameric mitochondrial chaperonin |
physical |
1 |
1 |
1 |
Two-hybrid |
HAS1 |
YMR290C |
ATP-dependent RNA helicase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ADH1 |
YOL086C |
Alcohol dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ADH1 |
YOL086C |
Alcohol dehydrogenase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
COR1 |
YBL045C |
Core subunit of the ubiquinol-cytochrome c reductase complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ECM2 |
YBR065C |
Pre-mRNA splicing factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
EMW1 |
YNL313C |
Essential conserved protein with a role in cell wall integrity |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
BRE1 |
YDL074C |
E3 ubiquitin ligase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
FRT2 |
YAL028W |
Tail-anchored ER membrane protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ARL1 |
YBR164C |
Soluble GTPase with a role in regulation of membrane traffic |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ARL1 |
YBR164C |
Soluble GTPase with a role in regulation of membrane traffic |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
GUS1 |
YGL245W |
Glutamyl-tRNA synthetase (GluRS) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BMH1 |
YER177W |
14-3-3 protein, major isoform |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
DBP3 |
YGL078C |
RNA-Dependent ATPase, member of DExD/H-box family |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
FUN12 |
YAL035W |
Translation initiation factor eIF5B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
FUN12 |
YAL035W |
Translation initiation factor eIF5B |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
DED1 |
YOR204W |
ATP-dependent DEAD-box RNA helicase with strand-annealing activity |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CBC2 |
YPL178W |
Small subunit of the heterodimeric cap binding complex with Sto1p |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
GCD11 |
YER025W |
Gamma subunit of the translation initiation factor eIF2 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HCR1 |
YLR192C |
eIF3j component of translation initiation factor 3 (eIF3) |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CFT2 |
YLR115W |
Subunit of the mRNA cleavage and polyadenlylation factor (CPF) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CFT1 |
YDR301W |
RNA-binding subunit of the mRNA cleavage and polyadenylation factor |
physical |
1 |
1 |
1 |
Two-hybrid |
GIR2 |
YDR152W |
Highly-acidic RWD domain-containing cytoplasmic protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ECM16 |
YMR128W |
Essential DEAH-box ATP-dependent RNA helicase specific to U3 snoRNP |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BMS1 |
YPL217C |
GTPase required for ribosomal subunit synthesis and rRNA processing |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
EFT2 |
YDR385W |
Elongation factor 2 (EF-2), also encoded by EFT1 |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
HGH1 |
YGR187C |
Chaperone protein for translation factor eEF2 |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ADE13 |
YLR359W |
Adenylosuccinate lyase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ADE4 |
YMR300C |
Phosphoribosylpyrophosphate amidotransferase (PRPPAT) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ATG14 |
YBR128C |
Autophagy-specific subunit of phosphatidylinositol 3-kinase complex I |
physical |
1 |
1 |
1 |
Two-hybrid |
APL2 |
YKL135C |
Beta-adaptin subunit of the clathrin-associated protein (AP-1) complex |
physical |
1 |
1 |
1 |
Two-hybrid |
APL5 |
YPL195W |
Delta adaptin-like subunit of the clathrin associated protein complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
APL6 |
YGR261C |
Beta3-like subunit of the yeast AP-3 complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ARC18 |
YLR370C |
Subunit of the ARP2/3 complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
ARC19 |
YKL013C |
Subunit of the ARP2/3 complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ARC35 |
YNR035C |
Subunit of the ARP2/3 complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ARC40 |
YBR234C |
Subunit of the ARP2/3 complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ARP2 |
YDL029W |
Essential component of the Arp2/3 complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ARP3 |
YJR065C |
Essential component of the Arp2/3 complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BEM1 |
YBR200W |
Protein containing SH3-domains |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
ASC1 |
YMR116C |
G-protein beta subunit and guanine dissociation inhibitor for Gpa2p |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
BEM2 |
YER155C |
Rho GTPase activating protein (RhoGAP) |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
BUD20 |
YLR074C |
C2H2-type zinc finger protein required for ribosome assembly |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CAP1 |
YKL007W |
Alpha subunit of the capping protein heterodimer (Cap1p and Cap2p) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CAF130 |
YGR134W |
Subunit of the CCR4-NOT transcriptional regulatory complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CDC28 |
YBR160W |
Cyclin-dependent kinase (CDK) catalytic subunit |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
CDC10 |
YCR002C |
Component of the septin ring, required for cytokinesis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CDC10 |
YCR002C |
Component of the septin ring, required for cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC12 |
YHR107C |
Component of the septin ring that is required for cytokinesis |
physical |
1 |
1 |
1 |
Two-hybrid |
ERG26 |
YGL001C |
C-3 sterol dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HDA1 |
YNL021W |
Catalytic subunit of class II HDA1 histone deacetylase complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
BUD31 |
YCR063W |
Component of the SF3b subcomplex of the U2 snRNP |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CHC1 |
YGL206C |
Clathrin heavy chain |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
COP1 |
YDL145C |
Alpha subunit of COPI vesicle coatomer complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CTK1 |
YKL139W |
Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
DCP2 |
YNL118C |
Catalytic subunit of Dcp1p-Dcp2p decapping enzyme complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ECM1 |
YAL059W |
Pre-ribosomal factor involved in 60S ribosomal protein subunit export |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
EDE1 |
YBL047C |
Scaffold protein involved in the formation of early endocytic sites |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ENO1 |
YGR254W |
Enolase I, a phosphopyruvate hydratase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ERG13 |
YML126C |
3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
FPR1 |
YNL135C |
Peptidyl-prolyl cis-trans isomerase (PPIase) |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
FRS1 |
YLR060W |
Beta subunit of cytoplasmic phenylalanyl-tRNA synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GCN2 |
YDR283C |
Protein kinase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
GCN1 |
YGL195W |
Positive regulator of the Gcn2p kinase activity |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GGA2 |
YHR108W |
Protein that regulates Arf1p, Arf2p to facilitate Golgi trafficking |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GLO3 |
YER122C |
ADP-ribosylation factor GTPase activating protein (ARF GAP) |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
GTR2 |
YGR163W |
Subunit of a TORC1-stimulating GTPase and the EGO/GSE complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
HAP2 |
YGL237C |
Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
HAT2 |
YEL056W |
Subunit of the Hat1p-Hat2p histone acetyltransferase complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DYN1 |
YKR054C |
Cytoplasmic heavy chain dynein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
HHF1 |
YBR009C |
Histone H4 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HIS4 |
YCL030C |
Multifunctional enzyme containing phosphoribosyl-ATP pyrophosphatase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
AEP2 |
YMR282C |
Mitochondrial protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
AEP2 |
YMR282C |
Mitochondrial protein |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
ACK1 |
YDL203C |
Protein that functions in the cell wall integrity pathway |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
COG8 |
YML071C |
Component of the conserved oligomeric Golgi complex |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
ARB1 |
YER036C |
ATPase of the ATP-binding cassette (ABC) family |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CRM1 |
YGR218W |
Nuclear export factor, exportin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GFA1 |
YKL104C |
Glutamine-fructose-6-phosphate amidotransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
FAB1 |
YFR019W |
1-phosphatidylinositol-3-phosphate 5-kinase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
FBA1 |
YKL060C |
Fructose 1,6-bisphosphate aldolase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
FBA1 |
YKL060C |
Fructose 1,6-bisphosphate aldolase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
HRR25 |
YPL204W |
Conserved casein kinase, monopolin subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BUD3 |
YCL014W |
Guanine nucleotide exchange factor (GEF) for Cdc42p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HDA3 |
YPR179C |
Subunit of HDA1 histone deacetylase complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
HDA2 |
YDR295C |
Subunit of HDA1 histone deacetylase complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ATG3 |
YNR007C |
E2-like enzyme |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
HER1 |
YOR227W |
Protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
FAS2 |
YPL231W |
Alpha subunit of fatty acid synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GIM3 |
YNL153C |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
APM1 |
YPL259C |
Mu1-like medium subunit of the AP-1 complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
DIG1 |
YPL049C |
MAP kinase-responsive inhibitor of the Ste12p transcription factor |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
STE11 |
YLR362W |
Signal transducing MEK kinase |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
SBA1 |
YKL117W |
Co-chaperone that binds and regulates Hsp90 family chaperones |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SSA3 |
YBL075C |
ATPase involved in protein folding and the response to stress |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
TAH1 |
YCR060W |
Component of conserved R2TP complex (Rvb1-Rvb2-Tah1-Pih1) |
genetic |
1 |
1 |
1 |
Dosage Rescue |
RTG3 |
YBL103C |
bHLH/Zip transcription factor for retrograde (RTG) and TOR pathways |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
SPS22 |
YCL048W |
Protein of unknown function |
physical |
1 |
1 |
1 |
Two-hybrid |
VAC17 |
YCL063W |
Phosphoprotein involved in vacuole inheritance |
physical |
1 |
1 |
1 |
Two-hybrid |
VAC17 |
YCL063W |
Phosphoprotein involved in vacuole inheritance |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PAT1 |
YCR077C |
Deadenylation-dependent mRNA-decapping factor |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SOR2 |
YDL246C |
Sorbitol dehydrogenase |
physical |
1 |
1 |
1 |
Two-hybrid |
YDR131C |
YDR131C |
F-box protein subunit of SCF ubiquitin ligase complex |
physical |
1 |
1 |
1 |
Two-hybrid |
MTH1 |
YDR277C |
Negative regulator of the glucose-sensing signal transduction pathway |
physical |
1 |
1 |
1 |
Two-hybrid |
MTH1 |
YDR277C |
Negative regulator of the glucose-sensing signal transduction pathway |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PRO1 |
YDR300C |
Gamma-glutamyl kinase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PEP7 |
YDR323C |
Adaptor protein involved in vesicle-mediated vacuolar protein sorting |
physical |
1 |
1 |
1 |
Two-hybrid |
MIG3 |
YER028C |
Transcriptional regulator |
physical |
1 |
1 |
1 |
Two-hybrid |
MIG1 |
YGL035C |
Transcription factor involved in glucose repression |
physical |
1 |
1 |
1 |
Two-hybrid |
LYS5 |
YGL154C |
Phosphopantetheinyl transferase involved in lysine biosynthesis |
physical |
1 |
1 |
1 |
Two-hybrid |
SEC15 |
YGL233W |
Essential 113 kDa subunit of the exocyst complex |
physical |
1 |
1 |
1 |
Two-hybrid |
YGR067C |
YGR067C |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Two-hybrid |
SLX9 |
YGR081C |
Protein required for pre-rRNA processing |
physical |
1 |
1 |
1 |
Two-hybrid |
YGR117C |
YGR117C |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Two-hybrid |
PAU12 |
YGR294W |
Protein of unknown function |
physical |
1 |
1 |
1 |
Two-hybrid |
YAP3 |
YHL009C |
Basic leucine zipper (bZIP) transcription factor |
physical |
1 |
1 |
1 |
Two-hybrid |
TRM5 |
YHR070W |
tRNA(m(1)G37)methyltransferase |
physical |
1 |
1 |
1 |
Two-hybrid |
RPL42B |
YHR141C |
Ribosomal 60S subunit protein L42B |
physical |
1 |
1 |
1 |
Two-hybrid |
SVP26 |
YHR181W |
ER exit adaptor for Golgi mannosyltransferases |
physical |
1 |
1 |
1 |
Two-hybrid |
KGD1 |
YIL125W |
Subunit of the mitochondrial alpha-ketoglutarate dehydrogenase complex |
physical |
1 |
1 |
1 |
Two-hybrid |
KGD1 |
YIL125W |
Subunit of the mitochondrial alpha-ketoglutarate dehydrogenase complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SDL1 |
YIL167W |
Blocked reading frame otherwise encoding L-serine dehydratase |
physical |
1 |
1 |
1 |
Two-hybrid |
NSP1 |
YJL041W |
FG-nucleoporin component of central core of the nuclear pore complex |
physical |
1 |
1 |
1 |
Two-hybrid |
LMO1 |
YLL007C |
Homolog of mammalian ELMO (Engulfment and celL MOtility) |
physical |
1 |
1 |
1 |
Two-hybrid |
RRN5 |
YLR141W |
Protein involved in transcription of rDNA by RNA polymerase I |
physical |
1 |
1 |
1 |
Two-hybrid |
VPS36 |
YLR417W |
Component of the ESCRT-II complex |
physical |
1 |
1 |
1 |
Two-hybrid |
VPS36 |
YLR417W |
Component of the ESCRT-II complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RPL6A |
YML073C |
Ribosomal 60S subunit protein L6A |
physical |
1 |
1 |
1 |
Two-hybrid |
RPS7B |
YNL096C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YNR071C |
YNR071C |
Putative aldose 1-epimerase |
physical |
1 |
1 |
1 |
Two-hybrid |
YNR071C |
YNR071C |
Putative aldose 1-epimerase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MED7 |
YOL135C |
Subunit of the RNA polymerase II mediator complex |
physical |
1 |
1 |
1 |
Two-hybrid |
TIR4 |
YOR009W |
Cell wall mannoprotein |
physical |
1 |
1 |
1 |
Two-hybrid |
PTC5 |
YOR090C |
Mitochondrial type 2C protein phosphatase (PP2C) |
physical |
1 |
1 |
1 |
Two-hybrid |
THI72 |
YOR192C |
Transporter of thiamine or related compound |
physical |
1 |
1 |
1 |
Two-hybrid |
SWI1 |
YPL016W |
Subunit of the SWI/SNF chromatin remodeling complex |
physical |
1 |
1 |
1 |
Two-hybrid |
SWI1 |
YPL016W |
Subunit of the SWI/SNF chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
TYW1 |
YPL207W |
Iron-sulfur protein required for synthesis of wybutosine modified tRNA |
physical |
1 |
1 |
1 |
Two-hybrid |
TYW1 |
YPL207W |
Iron-sulfur protein required for synthesis of wybutosine modified tRNA |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PDH1 |
YPR002W |
Putative 2-methylcitrate dehydratase |
physical |
1 |
1 |
1 |
Two-hybrid |
SMK1 |
YPR054W |
Middle sporulation-specific mitogen-activated protein kinase (MAPK) |
physical |
1 |
1 |
1 |
Two-hybrid |
MRD1 |
YPR112C |
Essential conserved small ribosomal subunit (40s) synthesis factor |
physical |
1 |
1 |
1 |
Two-hybrid |
POL12 |
YBL035C |
B subunit of DNA polymerase alpha-primase complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PIN4 |
YBL051C |
Protein involved in G2/M phase progression and response to DNA damage |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PIN4 |
YBL051C |
Protein involved in G2/M phase progression and response to DNA damage |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SEA4 |
YBL104C |
Subunit of SEACAT, a subcomplex of the SEA complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RKM3 |
YBR030W |
Ribosomal lysine methyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RKM3 |
YBR030W |
Ribosomal lysine methyltransferase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
PBY1 |
YBR094W |
Putative tubulin tyrosine ligase associated with P-bodies |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
IRA1 |
YBR140C |
GTPase-activating protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SMY2 |
YBR172C |
GYF domain protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
KTR4 |
YBR199W |
Glycosyltransferase involved in protein glycosylation |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
KCC4 |
YCL024W |
Protein kinase of the bud neck involved in the septin checkpoint |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PWP2 |
YCR057C |
Conserved 90S pre-ribosomal component |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NOP14 |
YDL148C |
Nucleolar protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NUS1 |
YDL193W |
Forms dehydrodolichyl diphosphate synthase complex with RER2 or SRT1 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YDL199C |
YDL199C |
Putative transporter |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SSB1 |
YDL229W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PEX10 |
YDR265W |
Peroxisomal membrane E3 ubiquitin ligase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PKH1 |
YDR490C |
Serine/threonine protein kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PKH1 |
YDR490C |
Serine/threonine protein kinase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
NUG1 |
YER006W |
GTPase that associates with nuclear 60S pre-ribosomes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ILV1 |
YER086W |
Threonine deaminase, catalyzes first step in isoleucine biosynthesis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SPT15 |
YER148W |
TATA-binding protein (TBP) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HXT10 |
YFL011W |
Hexose transporter |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
IES1 |
YFL013C |
Subunit of the INO80 chromatin remodeling complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
LSB3 |
YFR024C-A |
Protein containing a C-terminal SH3 domain |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
STT3 |
YGL022W |
Catalytic subunit of the oligosaccharyltransferase complex of the ER l |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MON1 |
YGL124C |
Subunit of a heterodimeric guanine nucleotide exchange factor (GEF) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MON1 |
YGL124C |
Subunit of a heterodimeric guanine nucleotide exchange factor (GEF) |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
RNR4 |
YGR180C |
Ribonucleotide-diphosphate reductase (RNR) small subunit |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RPN1 |
YHR027C |
Non-ATPase base subunit of the 19S RP of the 26S proteasome |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
LAM4 |
YHR080C |
Sterol-binding protein that localizes to puncta in the cortical ER |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SMN1 |
YHR202W |
Putative AMP hydrolase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PDR11 |
YIL013C |
ATP-binding cassette (ABC) transporter |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPB3 |
YIL021W |
RNA polymerase II third largest subunit B44 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPB3 |
YIL021W |
RNA polymerase II third largest subunit B44 |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SMC3 |
YJL074C |
Subunit of the multiprotein cohesin complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TIF2 |
YJL138C |
Translation initiation factor eIF4A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPA34 |
YJL148W |
RNA polymerase I subunit A34.5 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
IML1 |
YJR138W |
GTPase-activating protein (GAP) subunit of the Iml1p/SEACIT complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
OSH6 |
YKR003W |
Oxysterol-binding phosphatidylserine transferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SOF1 |
YLL011W |
Protein required for biogenesis of 40S (small) ribosomal subunit |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RPL22A |
YLR061W |
Ribosomal 60S subunit protein L22A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL22A |
YLR061W |
Ribosomal 60S subunit protein L22A |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MEF1 |
YLR069C |
Mitochondrial elongation factor involved in translational elongation |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YPT6 |
YLR262C |
Rab family GTPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YSH1 |
YLR277C |
Endoribonuclease |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RAD52 |
YML032C |
Protein involved in homologous recombination |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MOT3 |
YMR070W |
Transcriptional repressor, activator |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RCO1 |
YMR075W |
Essential component of the Rpd3S histone deacetylase complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NPL6 |
YMR091C |
Component of the RSC chromatin remodeling complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NPL6 |
YMR091C |
Component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
UBP10 |
YNL186W |
Ubiquitin-specific protease, deubiquitinates Ub-protein moieties |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SRP1 |
YNL189W |
Karyopherin alpha homolog |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PRP2 |
YNR011C |
RNA-dependent DExD/H-box ATPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MRPL50 |
YNR022C |
Mitochondrial ribosomal protein of the large subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SSK2 |
YNR031C |
MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HTZ1 |
YOL012C |
Histone variant H2AZ |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PNT1 |
YOR266W |
Mitochondrial integral inner membrane protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SNU66 |
YOR308C |
Component of the U4/U6.U5 snRNP complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
VMA4 |
YOR332W |
Subunit E of the V1 domain of the vacuolar H+-ATPase (V-ATPase) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YPR089W |
YPR089W |
Protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SKI3 |
YPR189W |
Ski complex component and TPR protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NAF1 |
YNL124W |
RNA-binding protein required for the assembly of box H/ACA snoRNPs |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SHE4 |
YOR035C |
Protein containing a UCS (UNC-45/CRO1/SHE4) domain |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
TPM1 |
YNL079C |
Major isoform of tropomyosin |
physical |
1 |
1 |
1 |
Two-hybrid |
KSS1 |
YGR040W |
Mitogen-activated protein kinase (MAPK) |
physical |
1 |
1 |
1 |
Two-hybrid |
YCK1 |
YHR135C |
Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform |
physical |
1 |
1 |
1 |
Two-hybrid |
YCK1 |
YHR135C |
Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PDR3 |
YBL005W |
Transcriptional activator of the pleiotropic drug resistance network |
physical |
1 |
1 |
1 |
Two-hybrid |
OAF3 |
YKR064W |
Putative transcriptional repressor with Zn(2)-Cys(6) finger |
physical |
1 |
1 |
1 |
Two-hybrid |
NET1 |
YJL076W |
Core subunit of the RENT complex |
physical |
1 |
1 |
1 |
Two-hybrid |
SAP30 |
YMR263W |
Component of Rpd3L histone deacetylase complex |
physical |
1 |
1 |
1 |
Two-hybrid |
SAP30 |
YMR263W |
Component of Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
SIR2 |
YDL042C |
Conserved NAD+ dependent histone deacetylase of the Sirtuin family |
physical |
1 |
1 |
1 |
Two-hybrid |
WTM2 |
YOR229W |
Transcriptional modulator |
physical |
1 |
1 |
1 |
Two-hybrid |
NMD5 |
YJR132W |
Karyopherin |
physical |
1 |
1 |
1 |
Two-hybrid |
NUP57 |
YGR119C |
FG-nucleoporin component of central core of the nuclear pore complex |
physical |
1 |
1 |
1 |
Two-hybrid |
RAS1 |
YOR101W |
GTPase involved in G-protein signaling in adenylate cyclase activation |
physical |
1 |
1 |
1 |
Two-hybrid |
YPT7 |
YML001W |
Rab family GTPase |
physical |
1 |
1 |
1 |
Two-hybrid |
YPT31 |
YER031C |
Rab family GTPase |
physical |
1 |
1 |
1 |
Two-hybrid |
YPT53 |
YNL093W |
Stress-induced Rab family GTPase |
physical |
1 |
1 |
1 |
Two-hybrid |
PEP12 |
YOR036W |
Target membrane receptor (t-SNARE) |
physical |
1 |
1 |
1 |
Two-hybrid |
SFT1 |
YKL006C-A |
Intra-Golgi v-SNARE |
physical |
1 |
1 |
1 |
Two-hybrid |
TFG2 |
YGR005C |
TFIIF (Transcription Factor II) middle subunit |
physical |
1 |
1 |
1 |
Two-hybrid |
TVP23 |
YDR084C |
Integral membrane protein |
physical |
1 |
1 |
1 |
Two-hybrid |
VPS55 |
YJR044C |
Late endosomal protein involved in late endosome to vacuole transport |
physical |
1 |
1 |
1 |
Two-hybrid |
YIP5 |
YGL161C |
Protein that interacts with Rab GTPases |
physical |
1 |
1 |
1 |
Two-hybrid |
MAL11 |
YGR289C |
High-affinity maltose transporter (alpha-glucoside transporter) |
physical |
1 |
1 |
1 |
Two-hybrid |
MAL11 |
YGR289C |
High-affinity maltose transporter (alpha-glucoside transporter) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
HXT1 |
YHR094C |
Low-affinity glucose transporter of the major facilitator superfamily |
physical |
1 |
1 |
1 |
Two-hybrid |
HXT5 |
YHR096C |
Hexose transporter with moderate affinity for glucose |
physical |
1 |
1 |
1 |
Two-hybrid |
HXT17 |
YNR072W |
Putative transmembrane polyol transporter |
physical |
1 |
1 |
1 |
Two-hybrid |
HXT17 |
YNR072W |
Putative transmembrane polyol transporter |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
LYP1 |
YNL268W |
Lysine permease |
physical |
1 |
1 |
1 |
Two-hybrid |
MPH2 |
YDL247W |
Alpha-glucoside permease |
physical |
1 |
1 |
1 |
Two-hybrid |
MUP1 |
YGR055W |
High affinity methionine permease |
physical |
1 |
1 |
1 |
Two-hybrid |
MUP3 |
YHL036W |
Low affinity methionine permease |
physical |
1 |
1 |
1 |
Two-hybrid |
MUP3 |
YHL036W |
Low affinity methionine permease |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PHO86 |
YJL117W |
Endoplasmic reticulum (ER) resident protein |
physical |
1 |
1 |
1 |
Two-hybrid |
PUT4 |
YOR348C |
Proline permease |
physical |
1 |
1 |
1 |
Two-hybrid |
QDR1 |
YIL120W |
Multidrug transporter of the major facilitator superfamily |
physical |
1 |
1 |
1 |
Two-hybrid |
TPO5 |
YKL174C |
Protein involved in excretion of putrescine and spermidine |
physical |
1 |
1 |
1 |
Two-hybrid |
YMR155W |
YMR155W |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Two-hybrid |
YPL264C |
YPL264C |
Endoplasmic reticulum protein of unknown function |
physical |
1 |
1 |
1 |
Two-hybrid |
YPR003C |
YPR003C |
Putative sulfate permease |
physical |
1 |
1 |
1 |
Two-hybrid |
HTB1 |
YDR224C |
Histone H2B |
physical |
1 |
1 |
1 |
Two-hybrid |
INP54 |
YOL065C |
Phosphatidylinositol 4,5-bisphosphate 5-phosphatase |
physical |
1 |
1 |
1 |
Two-hybrid |
IZH4 |
YOL101C |
Membrane protein involved in zinc ion homeostasis |
physical |
1 |
1 |
1 |
Two-hybrid |
MDH3 |
YDL078C |
Peroxisomal malate dehydrogenase |
physical |
1 |
1 |
1 |
Two-hybrid |
MET14 |
YKL001C |
Adenylylsulfate kinase |
physical |
1 |
1 |
1 |
Two-hybrid |
MNT3 |
YIL014W |
Alpha-1,3-mannosyltransferase |
physical |
1 |
1 |
1 |
Two-hybrid |
NOP15 |
YNL110C |
Constituent of 66S pre-ribosomal particles |
physical |
1 |
1 |
1 |
Two-hybrid |
NOP15 |
YNL110C |
Constituent of 66S pre-ribosomal particles |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
OLE1 |
YGL055W |
Delta(9) fatty acid desaturase |
physical |
1 |
1 |
1 |
Two-hybrid |
PEX11 |
YOL147C |
Peroxisomal protein required for medium-chain fatty acid oxidation |
physical |
1 |
1 |
1 |
Two-hybrid |
PDX3 |
YBR035C |
Pyridoxine (pyridoxamine) phosphate oxidase |
physical |
1 |
1 |
1 |
Two-hybrid |
PUT2 |
YHR037W |
Delta-1-pyrroline-5-carboxylate dehydrogenase |
physical |
1 |
1 |
1 |
Two-hybrid |
PYK2 |
YOR347C |
Pyruvate kinase |
physical |
1 |
1 |
1 |
Two-hybrid |
RRD2 |
YPL152W |
Peptidyl-prolyl cis/trans-isomerase |
physical |
1 |
1 |
1 |
Two-hybrid |
THI13 |
YDL244W |
Protein involved in synthesis of the thiamine precursor HMP |
physical |
1 |
1 |
1 |
Two-hybrid |
UBC6 |
YER100W |
Ubiquitin-conjugating enzyme involved in ERAD |
physical |
1 |
1 |
1 |
Two-hybrid |
UBX7 |
YBR273C |
UBX (ubiquitin regulatory X) domain-containing protein |
physical |
1 |
1 |
1 |
Two-hybrid |
SHO1 |
YER118C |
Transmembrane osmosensor for filamentous growth and HOG pathways |
physical |
1 |
1 |
1 |
Two-hybrid |
SMA2 |
YML066C |
Meiosis-specific prospore membrane protein |
physical |
1 |
1 |
1 |
Two-hybrid |
SOR1 |
YJR159W |
Sorbitol dehydrogenase |
physical |
1 |
1 |
1 |
Two-hybrid |
SRT1 |
YMR101C |
Forms the dehydrodolichyl diphosphate synthase (DDS) complex with NUS1 |
physical |
1 |
1 |
1 |
Two-hybrid |
TOM22 |
YNL131W |
Component of the TOM (Translocase of Outer Membrane) complex |
physical |
1 |
1 |
1 |
Two-hybrid |
WHI5 |
YOR083W |
Repressor of G1 transcription |
physical |
1 |
1 |
1 |
Two-hybrid |
XYL2 |
YLR070C |
Xylitol dehydrogenase |
physical |
1 |
1 |
1 |
Two-hybrid |
XYL2 |
YLR070C |
Xylitol dehydrogenase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YJL114W |
YJL114W |
Retrotransposon TYA Gag gene co-transcribed with TYB Pol |
physical |
1 |
1 |
1 |
Two-hybrid |
RDS1 |
YCR106W |
Putative zinc cluster transcription factor |
physical |
1 |
1 |
1 |
Two-hybrid |
STS1 |
YIR011C |
Protein required for localizing proteasomes to the nucleus |
physical |
1 |
1 |
1 |
Two-hybrid |
MRPS5 |
YBR251W |
Mitochondrial ribosomal protein of the small subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YLF2 |
YHL014C |
Protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YLF2 |
YHL014C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
LYS12 |
YIL094C |
Homo-isocitrate dehydrogenase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SRP72 |
YPL210C |
Core component of the signal recognition particle (SRP) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SMI1 |
YGR229C |
Protein involved in the regulation of cell wall synthesis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SMI1 |
YGR229C |
Protein involved in the regulation of cell wall synthesis |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
TPK1 |
YJL164C |
cAMP-dependent protein kinase catalytic subunit |
physical |
1 |
1 |
1 |
Biochemical Activity |
TPK3 |
YKL166C |
cAMP-dependent protein kinase catalytic subunit |
physical |
1 |
1 |
1 |
Biochemical Activity |
PKP2 |
YGL059W |
Mitochondrial protein kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
NNK1 |
YKL171W |
Protein kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
YOL029C |
YOL029C |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Two-hybrid |
TIF6 |
YPR016C |
Constituent of 66S pre-ribosomal particles |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
URE2 |
YNL229C |
Nitrogen catabolite repression transcriptional regulator |
physical |
1 |
1 |
1 |
Reconstituted Complex |
RPN10 |
YHR200W |
Proteasome polyubiquitin receptor |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
NAB2 |
YGL122C |
Nuclear polyadenylated RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
SWE1 |
YJL187C |
Protein kinase that regulates the G2/M transition |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
MCA1 |
YOR197W |
Ca2+-dependent cysteine protease |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TOM71 |
YHR117W |
Mitochondrial outer membrane protein |
physical |
1 |
1 |
1 |
Co-crystal Structure |
TOM71 |
YHR117W |
Mitochondrial outer membrane protein |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
LAS17 |
YOR181W |
Actin assembly factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SAN1 |
YDR143C |
Ubiquitin-protein ligase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NOP56 |
YLR197W |
Essential evolutionarily-conserved nucleolar protein |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
NOP56 |
YLR197W |
Essential evolutionarily-conserved nucleolar protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SPT7 |
YBR081C |
Subunit of the SAGA transcriptional regulatory complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SGF29 |
YCL010C |
Component of the HAT/Core module of the SAGA, SLIK, and ADA complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SGF29 |
YCL010C |
Component of the HAT/Core module of the SAGA, SLIK, and ADA complexes |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
UBP8 |
YMR223W |
Ubiquitin-specific protease component of the SAGA acetylation complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SGF73 |
YGL066W |
Subunit of DUBm module of SAGA and SLIK |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TAF5 |
YBR198C |
Subunit (90 kDa) of TFIID and SAGA complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TAF5 |
YBR198C |
Subunit (90 kDa) of TFIID and SAGA complexes |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
TAF6 |
YGL112C |
Subunit (60 kDa) of TFIID and SAGA complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TAF12 |
YDR145W |
Subunit (61/68 kDa) of TFIID and SAGA complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TAF12 |
YDR145W |
Subunit (61/68 kDa) of TFIID and SAGA complexes |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
REV3 |
YPL167C |
Catalytic subunit of DNA polymerase zeta |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NDI1 |
YML120C |
NADH:ubiquinone oxidoreductase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SBP1 |
YHL034C |
Protein that binds eIF4G and has a role in repression of translation |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RPB2 |
YOR151C |
RNA polymerase II second largest subunit B150 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
STE6 |
YKL209C |
Plasma membrane ATP-binding cassette (ABC) transporter |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
TFB4 |
YPR056W |
Subunit of TFIIH complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RLP7 |
YNL002C |
Nucleolar protein similar to large ribosomal subunit L7 proteins |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TRX2 |
YGR209C |
Cytoplasmic thioredoxin isoenzyme |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RPL28 |
YGL103W |
Ribosomal 60S subunit protein L28 |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RPP0 |
YLR340W |
Conserved ribosomal protein P0 of the ribosomal stalk |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RPL21A |
YBR191W |
Ribosomal 60S subunit protein L21A |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
NSR1 |
YGR159C |
Nucleolin, nucleolar protein that binds nuclear localization sequences |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RPP2A |
YOL039W |
Ribosomal protein P2 alpha |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RPL9A |
YGL147C |
Ribosomal 60S subunit protein L9A |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
RPL17A |
YKL180W |
Ribosomal 60S subunit protein L17A |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
NMA1 |
YLR328W |
Nicotinic acid mononucleotide adenylyltransferase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RPL37A |
YLR185W |
Ribosomal 60S subunit protein L37A |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
RPS29B |
YDL061C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RPL4A |
YBR031W |
Ribosomal 60S subunit protein L4A |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
IST2 |
YBR086C |
Cortical ER protein involved in ER-plasma membrane (PM) tethering |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PSP2 |
YML017W |
Asn rich cytoplasmic protein that contains RGG motifs |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SGN1 |
YIR001C |
Cytoplasmic RNA-binding protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RPS19A |
YOL121C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
RPL2A |
YFR031C-A |
Ribosomal 60S subunit protein L2A |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
ILV6 |
YCL009C |
Regulatory subunit of acetolactate synthase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
TDH1 |
YJL052W |
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 1 |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SSD1 |
YDR293C |
Translational repressor |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PRB1 |
YEL060C |
Vacuolar proteinase B (yscB) with H3 N-terminal endopeptidase activity |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
SCD6 |
YPR129W |
Repressor of translation initiation |
physical |
1 |
1 |
1 |
Two-hybrid |
JLP1 |
YLL057C |
Fe(II)-dependent sulfonate/alpha-ketoglutarate dioxygenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
JLP1 |
YLL057C |
Fe(II)-dependent sulfonate/alpha-ketoglutarate dioxygenase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PMU1 |
YKL128C |
Putative phosphomutase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS9B |
YBR189W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YRA1 |
YDR381W |
Nuclear polyadenylated RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MET3 |
YJR010W |
ATP sulfurylase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SHM1 |
YBR263W |
Mitochondrial serine hydroxymethyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
STM1 |
YLR150W |
Protein required for optimal translation under nutrient stress |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YGR283C |
YGR283C |
Putative methyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TSR1 |
YDL060W |
Protein required for processing of 20S pre-rRNA in the cytoplasm |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPA135 |
YPR010C |
RNA polymerase I second largest subunit A135 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MDJ1 |
YFL016C |
Co-chaperone that stimulates HSP70 protein Ssc1p ATPase activity |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NCL1 |
YBL024W |
S-adenosyl-L-methionine-dependent tRNA: m5C-methyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
UBA4 |
YHR111W |
E1-like protein that activates Urm1p before urmylation |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YMR265C |
YMR265C |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PDL32 |
YMR087W |
Putative ADP-ribose-1''-monophosphatase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NMD3 |
YHR170W |
Protein involved in nuclear export of the large ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
REB1 |
YBR049C |
RNA polymerase I enhancer binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YCK2 |
YNL154C |
Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NOB1 |
YOR056C |
Protein involved in proteasomal and 40S ribosomal subunit biogenesis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS10B |
YMR230W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
RIB4 |
YOL143C |
Lumazine synthase (DMRL synthase) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
KCS1 |
YDR017C |
Inositol hexakisphosphate and inositol heptakisphosphate kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
KCS1 |
YDR017C |
Inositol hexakisphosphate and inositol heptakisphosphate kinase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
TPS1 |
YBR126C |
Synthase subunit of trehalose-6-P synthase/phosphatase complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
RPS31 |
YLR167W |
Fusion protein cleaved to yield ribosomal protein S31 and ubiquitin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
THG1 |
YGR024C |
tRNAHis guanylyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MRPS18 |
YNL306W |
Mitochondrial ribosomal protein of the small subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RCL1 |
YOL010W |
Endonuclease that cleaves pre-rRNA at site A2 for 18S rRNA biogenesis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RIE1 |
YGR250C |
RNA binding protein and negative regulator of START |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PDC1 |
YLR044C |
Major of three pyruvate decarboxylase isozymes |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PPZ1 |
YML016C |
Serine/threonine protein phosphatase Z, isoform of Ppz2p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YPT1 |
YFL038C |
Rab family GTPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL6B |
YLR448W |
Ribosomal 60S subunit protein L6B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
LAF1 |
YMR102C |
Sterol-binding beta-propeller protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
URA2 |
YJL130C |
Bifunctional carbamoylphosphate synthetase/aspartate transcarbamylase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
KSP1 |
YHR082C |
Serine/threonine protein kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SRO9 |
YCL037C |
Cytoplasmic RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SRO9 |
YCL037C |
Cytoplasmic RNA-binding protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RNH1 |
YMR234W |
Ribonuclease H1 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PIG2 |
YIL045W |
Putative type-1 protein phosphatase targeting subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
KAR2 |
YJL034W |
ATPase involved in protein import into the ER |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YMR045C |
YMR045C |
Retrotransposon TYA Gag and TYB Pol genes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS1A |
YLR441C |
Ribosomal protein of the small (40S) subunit |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
LGE1 |
YPL055C |
Protein involved in histone H2B ubiquitination |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS23A |
YGR118W |
Ribosomal protein 28 (rp28) of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL42A |
YNL162W |
Ribosomal 60S subunit protein L42A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL3 |
YOR063W |
Ribosomal 60S subunit protein L3 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PBP4 |
YDL053C |
Pbp1p binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RRB1 |
YMR131C |
Specific assembly chaperone for ribosomal protein Rpl3p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL37B |
YDR500C |
Ribosomal 60S subunit protein L37B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RIM4 |
YHL024W |
Putative RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RIM4 |
YHL024W |
Putative RNA-binding protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YGR237C |
YGR237C |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YGR237C |
YGR237C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
PRP43 |
YGL120C |
RNA helicase in the DEAH-box family |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL43A |
YPR043W |
Ribosomal 60S subunit protein L43A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
UBP3 |
YER151C |
Ubiquitin-specific protease that cleaves Ub-protein fusions |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MRM1 |
YOR201C |
Ribose methyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SCS2 |
YER120W |
Integral ER membrane protein, regulates phospholipid metabolism |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YCL019W |
YCL019W |
Retrotransposon TYA Gag and TYB Pol genes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ROM2 |
YLR371W |
Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ROM2 |
YLR371W |
Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
RPL5 |
YPL131W |
Ribosomal 60S subunit protein L5 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL5 |
YPL131W |
Ribosomal 60S subunit protein L5 |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SNF4 |
YGL115W |
Activating gamma subunit of the AMP-activated Snf1p kinase complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SNF4 |
YGL115W |
Activating gamma subunit of the AMP-activated Snf1p kinase complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
SNF1 |
YDR477W |
AMP-activated S/T protein kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SNF1 |
YDR477W |
AMP-activated S/T protein kinase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
RPL35A |
YDL191W |
Ribosomal 60S subunit protein L35A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL35A |
YDL191W |
Ribosomal 60S subunit protein L35A |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
RPL14A |
YKL006W |
Ribosomal 60S subunit protein L14A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL14A |
YKL006W |
Ribosomal 60S subunit protein L14A |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MHP1 |
YJL042W |
Microtubule-associated protein involved in microtubule organization |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SIP2 |
YGL208W |
One of three alternate beta subunits of the Snf1 kinase complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS24A |
YER074W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL4B |
YDR012W |
Ribosomal 60S subunit protein L4B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL36B |
YPL249C-A |
Ribosomal 60S subunit protein L36B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPP1B |
YDL130W |
Ribosomal protein P1 beta |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL33A |
YPL143W |
Ribosomal 60S subunit protein L33A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPP1A |
YDL081C |
Ribosomal stalk protein P1 alpha |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPP1A |
YDL081C |
Ribosomal stalk protein P1 alpha |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RPC82 |
YPR190C |
RNA polymerase III subunit C82 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PMP1 |
YCR024C-A |
Regulatory subunit for the plasma membrane H(+)-ATPase Pma1p |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
TMA108 |
YIL137C |
Ribosome-associated, nascent chain binding factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TMA108 |
YIL137C |
Ribosome-associated, nascent chain binding factor |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
TMA46 |
YOR091W |
Protein of unknown function that associates with translating ribosomes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TOM70 |
YNL121C |
Component of the TOM (translocase of outer membrane) complex |
physical |
1 |
1 |
1 |
Reconstituted Complex |
TOM20 |
YGR082W |
Component of the TOM (translocase of outer membrane) complex |
physical |
1 |
1 |
1 |
Reconstituted Complex |
RPO21 |
YDL140C |
RNA polymerase II largest subunit B220 |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
PAB1 |
YER165W |
Poly(A) binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
IXR1 |
YKL032C |
Transcriptional repressor that regulates hypoxic genes during normoxia |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PUF4 |
YGL014W |
Member of the PUF protein family |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
IDS2 |
YJL146W |
Protein involved in modulation of Ime2p activity during meiosis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
IDS2 |
YJL146W |
Protein involved in modulation of Ime2p activity during meiosis |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
HXK1 |
YFR053C |
Hexokinase isoenzyme 1 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HXK2 |
YGL253W |
Hexokinase isoenzyme 2 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HYR1 |
YIR037W |
Glutathione peroxidase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
IDH1 |
YNL037C |
Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
IDH2 |
YOR136W |
Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ILV5 |
YLR355C |
Acetohydroxyacid reductoisomerase and mtDNA binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
IML2 |
YJL082W |
Protein required for clearance of inclusion bodies |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
IML2 |
YJL082W |
Protein required for clearance of inclusion bodies |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
IRC24 |
YIR036C |
Putative benzil reductase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
KAP104 |
YBR017C |
Transportin or cytosolic karyopherin beta 2 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
KAP123 |
YER110C |
Karyopherin beta |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
KAP95 |
YLR347C |
Karyopherin beta |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
KAP95 |
YLR347C |
Karyopherin beta |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
KES1 |
YPL145C |
Sterol/phosphatidylinositol-4-phosphate (PI(4)P) exchanger |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
KTR1 |
YOR099W |
Alpha-1,2-mannosyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
LEU2 |
YCL018W |
Beta-isopropylmalate dehydrogenase (IMDH) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MCM7 |
YBR202W |
Component of the Mcm2-7 hexameric helicase complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MES1 |
YGR264C |
Methionyl-tRNA synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MIR1 |
YJR077C |
Mitochondrial phosphate carrier |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MIR1 |
YJR077C |
Mitochondrial phosphate carrier |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
MPD2 |
YOL088C |
Member of the protein disulfide isomerase (PDI) family |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MPM1 |
YJL066C |
Mitochondrial intermembrane space protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MRI1 |
YPR118W |
5'-methylthioribose-1-phosphate isomerase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MRS6 |
YOR370C |
Rab escort protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MTD1 |
YKR080W |
NAD-dependent 5,10-methylenetetrahydrafolate dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MTR4 |
YJL050W |
RNA duplex-sensing translocase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MYO2 |
YOR326W |
Type V myosin motor involved in actin-based transport of cargos |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NAP1 |
YKR048C |
Histone chaperone and assembly chaperone for Rps6a/b |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NBP35 |
YGL091C |
Essential cytoplasmic iron-sulfur cluster binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NDE1 |
YMR145C |
Mitochondrial external NADH dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NEW1 |
YPL226W |
Translation termination and ribosome biogenesis factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
OLA1 |
YBR025C |
P-loop ATPase with similarity to human OLA1 and bacterial YchF |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
OM45 |
YIL136W |
Mitochondrial outer membrane protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
OM45 |
YIL136W |
Mitochondrial outer membrane protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PDA1 |
YER178W |
E1 alpha subunit of the pyruvate dehydrogenase (PDH) complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PDA1 |
YER178W |
E1 alpha subunit of the pyruvate dehydrogenase (PDH) complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
PDB1 |
YBR221C |
E1 beta subunit of the pyruvate dehydrogenase (PDH) complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PDB1 |
YBR221C |
E1 beta subunit of the pyruvate dehydrogenase (PDH) complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
PEP4 |
YPL154C |
Vacuolar aspartyl protease (proteinase A) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PEP4 |
YPL154C |
Vacuolar aspartyl protease (proteinase A) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PGA3 |
YML125C |
Putative cytochrome b5 reductase, localized to the plasma membrane |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PGI1 |
YBR196C |
Glycolytic enzyme phosphoglucose isomerase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PGM2 |
YMR105C |
Phosphoglucomutase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PHO85 |
YPL031C |
Cyclin-dependent kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PIL1 |
YGR086C |
Eisosome core component |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PIM1 |
YBL022C |
ATP-dependent Lon protease |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
POL30 |
YBR088C |
Proliferating cell nuclear antigen (PCNA) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PRM15 |
YMR278W |
Phosphoribomutase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PRO2 |
YOR323C |
Gamma-glutamyl phosphate reductase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PRO3 |
YER023W |
Delta 1-pyrroline-5-carboxylate reductase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PSA1 |
YDL055C |
GDP-mannose pyrophosphorylase (mannose-1-phosphate guanyltransferase) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PSE1 |
YMR308C |
Karyopherin/importin that interacts with the nuclear pore complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PSE1 |
YMR308C |
Karyopherin/importin that interacts with the nuclear pore complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PST2 |
YDR032C |
FMN-dependent NAD(P)H:quinone oxidoreductase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PYC2 |
YBR218C |
Pyruvate carboxylase isoform |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
QCR2 |
YPR191W |
Subunit 2 of ubiquinol cytochrome-c reductase (Complex III) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RBG2 |
YGR173W |
Protein with a role in translation |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RCN2 |
YOR220W |
Protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RET2 |
YFR051C |
Delta subunit of the coatomer complex (COPI) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RET2 |
YFR051C |
Delta subunit of the coatomer complex (COPI) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RET3 |
YPL010W |
Zeta subunit of the coatomer complex (COPI) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RFA1 |
YAR007C |
Subunit of heterotrimeric Replication Protein A (RPA) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RNA1 |
YMR235C |
GTPase activating protein (GAP) for Gsp1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RNR2 |
YJL026W |
Ribonucleotide-diphosphate reductase (RNR), small subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPN3 |
YER021W |
Essential non-ATPase regulatory subunit of the 26S proteasome lid |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPN3 |
YER021W |
Essential non-ATPase regulatory subunit of the 26S proteasome lid |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RPN5 |
YDL147W |
Subunit of the CSN and 26S proteasome lid complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPN6 |
YDL097C |
Essential, non-ATPase regulatory subunit of the 26S proteasome lid |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPN7 |
YPR108W |
Essential non-ATPase regulatory subunit of the 26S proteasome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPN8 |
YOR261C |
Essential non-ATPase regulatory subunit of the 26S proteasome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPT1 |
YKL145W |
ATPase of the 19S regulatory particle of the 26S proteasome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPT2 |
YDL007W |
ATPase of the 19S regulatory particle of the 26S proteasome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPT3 |
YDR394W |
ATPase of the 19S regulatory particle of the 26S proteasome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPT3 |
YDR394W |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RPT4 |
YOR259C |
ATPase of the 19S regulatory particle of the 26S proteasome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RTN2 |
YDL204W |
Reticulon protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RVB2 |
YPL235W |
ATP-dependent DNA helicase, also known as reptin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RVB2 |
YPL235W |
ATP-dependent DNA helicase, also known as reptin |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RVS161 |
YCR009C |
Amphiphysin-like lipid raft protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RVS161 |
YCR009C |
Amphiphysin-like lipid raft protein |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
RVS167 |
YDR388W |
Calmodulin-binding actin-associated protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SAC1 |
YKL212W |
Phosphatidylinositol phosphate phosphatase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SAC6 |
YDR129C |
Fimbrin, actin-bundling protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SAH1 |
YER043C |
S-adenosyl-L-homocysteine hydrolase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SAM1 |
YLR180W |
S-adenosylmethionine synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SDS24 |
YBR214W |
Protein involved in cell separation during budding |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SEC17 |
YBL050W |
Alpha-SNAP cochaperone |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SEC18 |
YBR080C |
AAA ATPase and SNARE disassembly chaperone |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SEC21 |
YNL287W |
Gamma subunit of coatomer |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SEC24 |
YIL109C |
Component of the Sec23p-Sec24p heterodimer of the COPII vesicle coat |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SEC28 |
YIL076W |
Epsilon-COP subunit of the coatomer |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SEC31 |
YDL195W |
Component of the Sec13p-Sec31p complex of the COPII vesicle coat |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SEC4 |
YFL005W |
Rab family GTPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SEC4 |
YFL005W |
Rab family GTPase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SER1 |
YOR184W |
3-phosphoserine aminotransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SES1 |
YDR023W |
Cytosolic seryl-tRNA synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SIS1 |
YNL007C |
Type II HSP40 co-chaperone that interacts with the HSP70 protein Ssa1p |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SLY1 |
YDR189W |
Hydrophilic protein involved in ER/Golgi vesicle trafficking |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SPF1 |
YEL031W |
P-type ATPase, ion transporter of the ER membrane |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SUB2 |
YDL084W |
Component of the TREX complex required for nuclear mRNA export |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SUP35 |
YDR172W |
Translation termination factor eRF3 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SUP45 |
YBR143C |
Polypeptide release factor (eRF1) in translation termination |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SXM1 |
YDR395W |
Nuclear transport factor (karyopherin) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TAL1 |
YLR354C |
Transaldolase, enzyme in the non-oxidative pentose phosphate pathway |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TKL1 |
YPR074C |
Transketolase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TMA19 |
YKL056C |
Protein that associates with ribosomes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TMA19 |
YKL056C |
Protein that associates with ribosomes |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
TOM40 |
YMR203W |
Component of the TOM (translocase of outer membrane) complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TPI1 |
YDR050C |
Triose phosphate isomerase, abundant glycolytic enzyme |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TRP2 |
YER090W |
Anthranilate synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TRP3 |
YKL211C |
Indole-3-glycerol-phosphate synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TRP5 |
YGL026C |
Tryptophan synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TRX1 |
YLR043C |
Cytoplasmic thioredoxin isoenzyme |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TSA1 |
YML028W |
Thioredoxin peroxidase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TSA2 |
YDR453C |
Stress inducible cytoplasmic thioredoxin peroxidase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TUB2 |
YFL037W |
Beta-tubulin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TUB2 |
YFL037W |
Beta-tubulin |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
UBA1 |
YKL210W |
Ubiquitin activating enzyme (E1) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
UBC4 |
YBR082C |
Ubiquitin-conjugating enzyme (E2) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
UBP6 |
YFR010W |
Ubiquitin-specific protease |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
URA7 |
YBL039C |
Major CTP synthase isozyme (see also URA8) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
VAC8 |
YEL013W |
Vacuole-specific Myo2p receptor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
VMA13 |
YPR036W |
Subunit H of the V1 peripheral membrane domain of V-ATPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
VMA13 |
YPR036W |
Subunit H of the V1 peripheral membrane domain of V-ATPase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
VMA2 |
YBR127C |
Subunit B of V1 peripheral membrane domain of vacuolar H+-ATPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
VMA5 |
YKL080W |
Subunit C of the V1 peripheral membrane domain of V-ATPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
VMA8 |
YEL051W |
Subunit D of the V1 peripheral membrane domain of V-ATPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
VPS1 |
YKR001C |
Dynamin-like GTPase required for vacuolar sorting |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
VPS1 |
YKR001C |
Dynamin-like GTPase required for vacuolar sorting |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
VPS4 |
YPR173C |
AAA-ATPase involved in multivesicular body (MVB) protein sorting |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
VPS4 |
YPR173C |
AAA-ATPase involved in multivesicular body (MVB) protein sorting |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
WTM1 |
YOR230W |
Transcriptional modulator |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YBR053C |
YBR053C |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YDR341C |
YDR341C |
Arginyl-tRNA synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YDR391C |
YDR391C |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YET1 |
YKL065C |
Endoplasmic reticulum transmembrane protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YHR020W |
YHR020W |
Prolyl-tRNA synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NRE1 |
YIR035C |
Putative cytoplasmic short-chain dehydrogenase/reductase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YJR096W |
YJR096W |
Xylose and arabinose reductase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YJU3 |
YKL094W |
Monoglyceride lipase (MGL) that hydrolyzes fatty acid ethyl esters |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TTI1 |
YKL033W |
Subunit of the ASTRA complex, involved in chromatin remodeling |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YKR018C |
YKR018C |
Protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YKT6 |
YKL196C |
Vesicle membrane protein (v-SNARE) with acyltransferase activity |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YMR226C |
YMR226C |
NADP(+)-dependent serine dehydrogenase and carbonyl reductase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PYP1 |
YNL010W |
Sugar alcohol phosphatase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SDD3 |
YOL098C |
Putative metalloprotease |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YOP1 |
YPR028W |
Reticulon-interacting protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YOR131C |
YOR131C |
Putative haloacid dehalogenase-like hydrolase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YPK1 |
YKL126W |
S/T protein kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YPL225W |
YPL225W |
Protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YPL225W |
YPL225W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YPR127W |
YPR127W |
Putative pyridoxine 4-dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YPT52 |
YKR014C |
Endosomal Rab family GTPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YRB1 |
YDR002W |
Ran GTPase binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YRB1 |
YDR002W |
Ran GTPase binding protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ZPR1 |
YGR211W |
Essential protein with two zinc fingers |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ZPR1 |
YGR211W |
Essential protein with two zinc fingers |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
NQM1 |
YGR043C |
Transaldolase of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL23B |
YER117W |
Ribosomal 60S subunit protein L23B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL23B |
YER117W |
Ribosomal 60S subunit protein L23B |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MDH1 |
YKL085W |
Mitochondrial malate dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MDH2 |
YOL126C |
Cytoplasmic malate dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MLS1 |
YNL117W |
Malate synthase, enzyme of the glyoxylate cycle |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MTC1 |
YJL123C |
Protein of unknown function that may interact with ribosomes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MXR1 |
YER042W |
Methionine-S-sulfoxide reductase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PAP1 |
YKR002W |
Poly(A) polymerase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PCK1 |
YKR097W |
Phosphoenolpyruvate carboxykinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SDH1 |
YKL148C |
Flavoprotein subunit of succinate dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SDS23 |
YGL056C |
Protein involved in cell separation during budding |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SOL4 |
YGR248W |
6-phosphogluconolactonase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TPS2 |
YDR074W |
Phosphatase subunit of the trehalose-6-P synthase/phosphatase complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TSL1 |
YML100W |
Large subunit of trehalose 6-phosphate synthase/phosphatase complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
UBC8 |
YEL012W |
Ubiquitin-conjugating enzyme that regulates gluconeogenesis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ZTA1 |
YBR046C |
NADPH-dependent quinone reductase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPT6 |
YGL048C |
ATPase of the 19S regulatory particle of the 26S proteasome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SSP120 |
YLR250W |
Protein packaged into COPII vesicles for ER to Golgi trafficking |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SUI2 |
YJR007W |
Alpha subunit of the translation initiation factor eIF2 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SUI2 |
YJR007W |
Alpha subunit of the translation initiation factor eIF2 |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
TCP1 |
YDR212W |
Alpha subunit of chaperonin-containing T-complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TCP1 |
YDR212W |
Alpha subunit of chaperonin-containing T-complex |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
UBP13 |
YBL067C |
Ubiquitin-specific protease that cleaves Ub-protein fusions |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
URA8 |
YJR103W |
Minor CTP synthase isozyme (see also URA7) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
VIP1 |
YLR410W |
Bifunctional inositol pyrophosphate kinase and phosphatase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
IKI3 |
YLR384C |
Subunit of Elongator complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ILV3 |
YJR016C |
Dihydroxyacid dehydratase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ILV3 |
YJR016C |
Dihydroxyacid dehydratase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MBF1 |
YOR298C-A |
Transcriptional coactivator |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MIS1 |
YBR084W |
Mitochondrial C1-tetrahydrofolate synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
OYE2 |
YHR179W |
Conserved NADPH oxidoreductase containing flavin mononucleotide (FMN) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PCM1 |
YEL058W |
Essential N-acetylglucosamine-phosphate mutase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PFK1 |
YGR240C |
Alpha subunit of heterooctameric phosphofructokinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PFK2 |
YMR205C |
Beta subunit of heterooctameric phosphofructokinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PTC3 |
YBL056W |
Type 2C protein phosphatase (PP2C) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RFA2 |
YNL312W |
Subunit of heterotrimeric Replication Protein A (RPA) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPG1 |
YBR079C |
eIF3a subunit of the eukaryotic translation initiation factor 3 (eIF3) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPN13 |
YLR421C |
Subunit of the 19S regulatory particle of the 26S proteasome lid |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPN9 |
YDR427W |
Non-ATPase regulatory subunit of the 26S proteasome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS16A |
YMR143W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RQC2 |
YPL009C |
Component of the Ribosome Quality Control (RQC) complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SGT2 |
YOR007C |
Glutamine-rich cytoplasmic cochaperone |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SOD1 |
YJR104C |
Cytosolic copper-zinc superoxide dismutase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
THR4 |
YCR053W |
Threonine synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
THR4 |
YCR053W |
Threonine synthase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
TIF3 |
YPR163C |
Translation initiation factor eIF-4B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TYS1 |
YGR185C |
Cytoplasmic tyrosyl-tRNA synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TYS1 |
YGR185C |
Cytoplasmic tyrosyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YNL134C |
YNL134C |
NADH-dependent aldehyde reductase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YPR148C |
YPR148C |
Protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ZUO1 |
YGR285C |
Ribosome-associated chaperone |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NUP2 |
YLR335W |
Nucleoporin involved in nucleocytoplasmic transport |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
LTP1 |
YPR073C |
Protein phosphotyrosine phosphatase of unknown cellular role |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPN2 |
YIL075C |
Subunit of the 26S proteasome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPN2 |
YIL075C |
Subunit of the 26S proteasome |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ILS1 |
YBL076C |
Cytoplasmic isoleucine-tRNA synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PRT1 |
YOR361C |
eIF3b subunit of the eukaryotic translation initiation factor 3 (eIF3) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SPT6 |
YGR116W |
Nucleosome remodeling protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SMC6 |
YLR383W |
Subunit of the SMC5-SMC6 complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS6A |
YPL090C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS7A |
YOR096W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS9A |
YPL081W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS10A |
YOR293W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
STE5 |
YDR103W |
Pheromone-responsive MAPK scaffold protein |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
RPN12 |
YFR052W |
Subunit of the 19S regulatory particle of the 26S proteasome lid |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SLA1 |
YBL007C |
Cytoskeletal protein binding protein |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
RRN10 |
YBL025W |
Protein involved in promoting high level transcription of rDNA |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
SHP1 |
YBL058W |
UBX domain-containing substrate adaptor for Cdc48p |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
MIX23 |
YBL107C |
Mitochondrial intermembrane space protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
SCO1 |
YBR037C |
Copper-binding protein of mitochondrial inner membrane |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
YSA1 |
YBR111C |
Nudix hydrolase family member with ADP-ribose pyrophosphatase activity |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
SEC66 |
YBR171W |
Non-essential subunit of Sec63 complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
UMP1 |
YBR173C |
Chaperone required for correct maturation of the 20S proteasome |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
ISW1 |
YBR245C |
ATPase subunit of imitation-switch (ISWI) class chromatin remodelers |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
PEX34 |
YCL056C |
Protein that regulates peroxisome populations |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
YCR090C |
YCR090C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
RPS16B |
YDL083C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
RPL41A |
YDL184C |
Ribosomal 60S subunit protein L41A |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
YDL206W |
YDL206W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
SHS1 |
YDL225W |
Component of the septin ring that is required for cytokinesis |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
SWF1 |
YDR126W |
Palmitoyltransferase that acts on transmembrane proteins |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
RGP1 |
YDR137W |
Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
NUM1 |
YDR150W |
Protein required for nuclear migration |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
UME6 |
YDR207C |
Rpd3L histone deacetylase complex subunit |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
SHE9 |
YDR393W |
Protein required for normal mitochondrial morphology |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
MRPL28 |
YDR462W |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
VPS52 |
YDR484W |
Component of the GARP (Golgi-associated retrograde protein) complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
NPR2 |
YEL062W |
Subunit of the Iml1p/SEACIT complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
SIT1 |
YEL065W |
Ferrioxamine B transporter |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
SLX8 |
YER116C |
Subunit of Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
RTR1 |
YER139C |
Dual specificity protein phosphatase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
UBP5 |
YER144C |
Putative ubiquitin-specific protease |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
PEA2 |
YER149C |
Coiled-coil 12S polarisome subunit |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
RAD4 |
YER162C |
Damaged-DNA binding subunit of Nuclear Excision Repair Factor 2 |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
YER187W |
YER187W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
RPO41 |
YFL036W |
Mitochondrial RNA polymerase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
PGD1 |
YGL025C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
YGL081W |
YGL081W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
SOH1 |
YGL127C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
HUR1 |
YGL168W |
Protein with a role in DNA repair |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
PDX1 |
YGR193C |
E3-binding protein of the mitochondrial pyruvate dehydrogenase complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
MGA1 |
YGR249W |
Protein similar to heat shock transcription factor |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
VMA16 |
YHR026W |
Subunit c'' of the vacuolar ATPase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
VMA10 |
YHR039C-A |
Subunit G of the V1 peripheral membrane domain of V-ATPase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
SRB2 |
YHR041C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
VMA22 |
YHR060W |
Protein that is required for vacuolar H+-ATPase (V-ATPase) function |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
MET18 |
YIL128W |
Component of cytosolic iron-sulfur protein assembly (CIA) machinery |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
MRS1 |
YIR021W |
Splicing protein |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
SMT1 |
YJL147C |
Translational repressor of the mitochondrial ATP6/8 mRNA |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
MNN11 |
YJL183W |
Subunit of a Golgi mannosyltransferase complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
NUC1 |
YJL208C |
Major mitochondrial nuclease |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
YJR011C |
YJR011C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
YJR084W |
YJR084W |
Protein that forms a complex with Thp3p |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
ILM1 |
YJR118C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
YJR120W |
YJR120W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
STR2 |
YJR130C |
Cystathionine gamma-synthase, converts cysteine into cystathionine |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
PRR1 |
YKL116C |
Serine/threonine protein kinase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
YKL162C |
YKL162C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
UTH1 |
YKR042W |
Mitochondrial inner membrane protein |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
MMM1 |
YLL006W |
ER integral membrane protein, ERMES complex subunit |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
RIC1 |
YLR039C |
Protein involved in retrograde transport to the cis-Golgi network |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
YLR046C |
YLR046C |
Putative membrane protein |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
SUL2 |
YLR092W |
High affinity sulfate permease |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
NYV1 |
YLR093C |
v-SNARE component of the vacuolar SNARE complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
IOC2 |
YLR095C |
Subunit of the Isw1b complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
MMR1 |
YLR190W |
Phosphorylated protein of the mitochondrial outer membrane |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
LIP2 |
YLR239C |
Lipoyl ligase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
SEC22 |
YLR268W |
R-SNARE protein |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
RPS30A |
YLR287C-A |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
MMS22 |
YLR320W |
Subunit of E3 ubiquitin ligase complex involved in replication repair |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
REC102 |
YLR329W |
Protein involved in early stages of meiotic recombination |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
VAC14 |
YLR386W |
Enzyme regulator |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
SST2 |
YLR452C |
GTPase-activating protein for Gpa1p |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
TRM9 |
YML014W |
tRNA methyltransferase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
VAN1 |
YML115C |
Component of the mannan polymerase I |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
SOK2 |
YMR016C |
Nuclear protein that negatively regulates pseudohyphal differentiation |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
PEX12 |
YMR026C |
C3HC4-type RING-finger peroxin and E3 ubiquitin ligase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
SAM37 |
YMR060C |
Component of the Sorting and Assembly Machinery (SAM) complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
REC114 |
YMR133W |
Protein involved in early stages of meiotic recombination |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
YIM1 |
YMR152W |
Aldehyde reductase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
NUP53 |
YMR153W |
FG-nucleoporin component of central core of nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
YMR158C-A |
YMR158C-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
MRE11 |
YMR224C |
Nuclease subunit of the MRX complex with Rad50p and Xrs2p |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
SCS7 |
YMR272C |
Sphingolipid alpha-hydroxylase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
LAT1 |
YNL071W |
Dihydrolipoamide acetyltransferase component (E2) of the PDC |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
MKS1 |
YNL076W |
Pleiotropic negative transcriptional regulator |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
TCB2 |
YNL087W |
ER protein involved in ER-plasma membrane tethering |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
KEX2 |
YNL238W |
Kexin, a subtilisin-like protease (proprotein convertase) |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
SIN3 |
YOL004W |
Component of both the Rpd3S and Rpd3L histone deacetylase complexes |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
RTC1 |
YOL138C |
Subunit of SEACAT, a subcomplex of the SEA complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
WHI2 |
YOR043W |
Negative regulator of TORC1 in response to limiting leucine |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
MSA1 |
YOR066W |
Activator of G1-specific transcription factors MBF and SBF |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
VPH1 |
YOR270C |
Subunit a of the vacuolar-ATPase V0 domain |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
TEA1 |
YOR337W |
Ty1 enhancer activator involved in Ty enhancer-mediated transcription |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
RMI1 |
YPL024W |
Subunit of the RecQ (Sgs1p) - Topo III (Top3p) complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
MRX11 |
YPL041C |
Protein that associates with mitochondrial ribosome |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
SUR1 |
YPL057C |
Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
YIG1 |
YPL201C |
Protein that interacts with glycerol 3-phosphatase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
MRPL51 |
YPR100W |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
KAR3 |
YPR141C |
Minus-end-directed microtubule motor |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
NCA2 |
YPR155C |
Protein that regulates expression of Fo-F1 ATP synthase subunits |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
TPO3 |
YPR156C |
Polyamine transporter of the major facilitator superfamily |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
RGR1 |
YLR071C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
NUT2 |
YPR168W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
ROX3 |
YBL093C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
SWC3 |
YAL011W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SYN8 |
YAL014C |
Endosomal SNARE related to mammalian syntaxin 8 |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
LDS1 |
YAL018C |
Protein Involved in spore wall assembly |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MYO4 |
YAL029C |
Type V myosin motor involved in actin-based transport of cargos |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SNC1 |
YAL030W |
Vesicle membrane receptor protein (v-SNARE) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PRP45 |
YAL032C |
Protein required for pre-mRNA splicing |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
POP5 |
YAL033W |
Subunit of both RNase MRP and nuclear RNase P |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RBG1 |
YAL036C |
Member of the DRG family of GTP-binding proteins |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SEO1 |
YAL067C |
Putative permease |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SWH1 |
YAR042W |
Protein similar to mammalian oxysterol-binding protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SHE1 |
YBL031W |
Mitotic spindle protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PSY4 |
YBL046W |
Regulatory subunit of protein phosphatase PP4 |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MOH1 |
YBL049W |
Protein of unknown function, essential for stationary phase survival |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
NUP170 |
YBL079W |
Subunit of inner ring of nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
POA1 |
YBR022W |
Phosphatase that is highly specific for ADP-ribose 1''-phosphate |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
REG2 |
YBR050C |
Regulatory subunit of the Glc7p type-1 protein phosphatase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
TRM7 |
YBR061C |
2'-O-ribose methyltransferase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YBR062C |
YBR062C |
Protein of unknown function that interacts with Msb2p |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YBR071W |
YBR071W |
Protein of unknown function found in the cytoplasm and bud neck |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
TOS1 |
YBR162C |
Covalently-bound cell wall protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MSI1 |
YBR195C |
Subunit of chromatin assembly factor I (CAF-1) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PRP5 |
YBR237W |
RNA helicase in the DEAD-box family |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RRT2 |
YBR246W |
Methylesterase performing penultimate step of diphthamide biosynthesis |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SPO23 |
YBR250W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MTC4 |
YBR255W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YBR259W |
YBR259W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RGD1 |
YBR260C |
GTPase-activating protein (RhoGAP) for Rho3p and Rho4p |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YCL001W-A |
YCL001W-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YCL002C |
YCL002C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
LDB16 |
YCL005W |
Protein involved in lipid droplet (LD) assembly |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
STP22 |
YCL008C |
Component of the ESCRT-I complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
NFS1 |
YCL017C |
Cysteine desulfurase involved in iron-sulfur cluster biogenesis |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
NPP1 |
YCR026C |
Nucleotide pyrophosphatase/phosphodiesterase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RPN4 |
YDL020C |
Transcription factor that stimulates expression of proteasome genes |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PEX19 |
YDL065C |
Chaperone and import receptor for newly-synthesized class I PMPs |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RPL35B |
YDL136W |
Ribosomal 60S subunit protein L35B |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PCL9 |
YDL179W |
Cyclin |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MRPL11 |
YDL202W |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
NHP2 |
YDL208W |
Protein related to mammalian high mobility group (HMG) proteins |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YDL211C |
YDL211C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SHR3 |
YDL212W |
Endoplasmic reticulum packaging chaperone |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
NOP6 |
YDL213C |
rRNA-binding protein required for 40S ribosomal subunit biogenesis |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
TIM22 |
YDL217C |
Essential core component of mitochondrial TIM22 complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
WHI4 |
YDL224C |
Putative RNA binding protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RCR2 |
YDR003W |
Vacuolar ubiquitin ligase-substrate adaptor |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RAD61 |
YDR014W |
Subunit of a complex that inhibits sister chromatid cohesion |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
NSI1 |
YDR026C |
RNA polymerase I termination factor |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YDR042C |
YDR042C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PPH3 |
YDR075W |
Catalytic subunit of protein phosphatase PP4 complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
TRS85 |
YDR108W |
Component of transport protein particle (TRAPP) complex III |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
TRM1 |
YDR120C |
tRNA methyltransferase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RPA14 |
YDR156W |
RNA polymerase I subunit A14 |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
NBP2 |
YDR162C |
Protein involved in the HOG (high osmolarity glycerol) pathway |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
NVJ3 |
YDR179W-A |
Protein with a potential role in tethering ER and vacuoles |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MET32 |
YDR253C |
Zinc-finger DNA-binding transcription factor |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SWM1 |
YDR260C |
Subunit of the anaphase-promoting complex (APC) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RTT103 |
YDR289C |
Protein involved in transcription termination by RNA polymerase II |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SUR2 |
YDR297W |
Sphinganine C4-hydroxylase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PMT7 |
YDR307W |
Putative protein mannosyltransferase similar to Pmt1p |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SWR1 |
YDR334W |
Swi2/Snf2-related ATPase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SAC7 |
YDR389W |
GTPase activating protein (GAP) for Rho1p |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YDR415C |
YDR415C |
Putative aminopeptidase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
LRS4 |
YDR439W |
Nucleolar protein that forms a complex with Csm1p |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YDR444W |
YDR444W |
Putative hydrolase acting on ester bonds |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
STP1 |
YDR463W |
Transcription factor |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SPP41 |
YDR464W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
VPS60 |
YDR486C |
Protein involved in late endosome to vacuole transport |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
WBP1 |
YEL002C |
Beta subunit of the oligosaccharyl transferase glycoprotein complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
VMA3 |
YEL027W |
Proteolipid subunit c of the V0 domain of vacuolar H(+)-ATPase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RMD6 |
YEL072W |
Protein required for sporulation |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MNN1 |
YER001W |
Alpha-1,3-mannosyltransferase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
TIR1 |
YER011W |
Cell wall mannoprotein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PRP22 |
YER013W |
DEAH-box RNA-dependent ATPase/ATP-dependent RNA helicase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ISC1 |
YER019W |
Inositol phosphosphingolipid phospholipase C |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YER034W |
YER034W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YER039C-A |
YER039C-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
VTC1 |
YER072W |
Regulatory subunit of the vacuolar transporter chaperone (VTC) complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
IES5 |
YER092W |
Non-essential INO80 chromatin remodeling complex subunit |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YCK3 |
YER123W |
Palmitoylated vacuolar membrane-localized casein kinase I isoform |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SPB4 |
YFL002C |
Putative ATP-dependent RNA helicase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SMX2 |
YFL017W-A |
Core Sm protein Sm G |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PAU5 |
YFL020C |
Member of the seripauperin multigene family |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RPL22B |
YFL034C-A |
Ribosomal 60S subunit protein L22A |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
LAM5 |
YFL042C |
Putative sterol transfer protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YFL051C |
YFL051C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
LOC1 |
YFR001W |
Nucleolar protein involved in the asymmetric localization of ASH1 mRNA |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YFR006W |
YFR006W |
Putative X-Pro aminopeptidase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YFH7 |
YFR007W |
Putative kinase with similarity to the PRK/URK/PANK kinase subfamily |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MIC19 |
YFR011C |
Component of the MICOS complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
IOC3 |
YFR013W |
Subunit of the Isw1a complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
IGD1 |
YFR017C |
Cytoplasmic protein that inhibits Gdb1p glycogen debranching activity |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YFR018C |
YFR018C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ROG3 |
YFR022W |
Alpha-arrestin involved in ubiquitin-dependent endocytosis |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PES4 |
YFR023W |
Poly(A) binding protein, suppressor of DNA polymerase epsilon mutation |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
IRC6 |
YFR043C |
Clathrin coat accessory factor |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PDR1 |
YGL013C |
Transcription factor that regulates the pleiotropic drug response |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RNA15 |
YGL044C |
Component of the cleavage and polyadenylation factor I (CF I) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RIM8 |
YGL045W |
Protein involved in proteolytic activation of Rim101p |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MAD1 |
YGL086W |
Coiled-coil protein involved in spindle-assembly checkpoint |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PAN2 |
YGL094C |
Catalytic subunit of the Pan2p-Pan3p poly(A)-ribonuclease complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
USE1 |
YGL098W |
Essential SNARE protein localized to the ER |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
VPS73 |
YGL104C |
Mitochondrial protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
NUT1 |
YGL151W |
Component of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SUA5 |
YGL169W |
Protein involved in threonylcarbamoyl adenosine biosynthesis |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MIG2 |
YGL209W |
Zinc finger transcriptional repressor |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YPT32 |
YGL210W |
Rab family GTPase involved in the exocytic pathway |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
OST5 |
YGL226C-A |
Zeta subunit of the oligosaccharyltransferase complex of the ER lumen |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RTG2 |
YGL252C |
Sensor of mitochondrial dysfunction |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MCO32 |
YGR053C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
VOA1 |
YGR106C |
ER protein that functions in assembly of the V0 sector of V-ATPase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YGR122W |
YGR122W |
Protein that may be involved in pH regulation |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
VSB1 |
YGR125W |
Vacuolar membrane protein required for uptake and storage of arginine |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YGR127W |
YGR127W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
UTP8 |
YGR128C |
Nucleolar protein required for export of tRNAs from the nucleus |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YGR130C |
YGR130C |
Component of the eisosome with unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
THI4 |
YGR144W |
Thiazole synthase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
UBR1 |
YGR184C |
E3 ubiquitin ligase (N-recognin) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PCT1 |
YGR202C |
Cholinephosphate cytidylyltransferase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PUP2 |
YGR253C |
Alpha 5 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YHL012W |
YHL012W |
Putative UTP glucose-1-phosphate uridylyltransferase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
NPR3 |
YHL023C |
Subunit of the Iml1p/SEACIT complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RIM101 |
YHL027W |
Cys2His2 zinc-finger transcriptional repressor |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
OCA5 |
YHL029C |
Cytoplasmic protein required for replication of Brome mosaic virus |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
QCR10 |
YHR001W-A |
Subunit of the ubiqunol-cytochrome c oxidoreductase complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
NEM1 |
YHR004C |
Probable catalytic subunit of Nem1p-Spo7p phosphatase holoenzyme |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
STP2 |
YHR006W |
Transcription factor |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
VPS29 |
YHR012W |
Subunit of the membrane-associated retromer complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
THR1 |
YHR025W |
Homoserine kinase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YHI9 |
YHR029C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
INM1 |
YHR046C |
Inositol monophosphatase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MED6 |
YHR058C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RPP1 |
YHR062C |
Subunit of both RNase MRP and nuclear RNase P |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
OSH3 |
YHR073W |
Member of an oxysterol-binding protein family |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PPE1 |
YHR075C |
Protein with carboxyl methyl esterase activity |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
IRE1 |
YHR079C |
Serine-threonine kinase and endoribonuclease |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RTC3 |
YHR087W |
Protein of unknown function involved in RNA metabolism |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
HXT4 |
YHR092C |
High-affinity glucose transporter |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PEX28 |
YHR150W |
Peroxisomal integral membrane peroxin |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SPO12 |
YHR152W |
Nucleolar protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
KEL1 |
YHR158C |
Protein required for proper cell fusion and cell morphology |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PEX18 |
YHR160C |
Peroxin |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
THP2 |
YHR167W |
Subunit of the THO and TREX complexes |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MTG2 |
YHR168W |
Putative GTPase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SPC97 |
YHR172W |
Component of the microtubule-nucleating Tub4p (gamma-tubulin) complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
NVJ1 |
YHR195W |
Nuclear envelope protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YIL001W |
YIL001W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
VID28 |
YIL017C |
GID Complex subunit, serves as adaptor for regulatory subunit Vid24p |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YKE4 |
YIL023C |
Zinc transporter |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SYG1 |
YIL047C |
Plasma membrane protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
NEO1 |
YIL048W |
Phospholipid translocase (flippase) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RGI2 |
YIL057C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RCI37 |
YIL077C |
Protein that associates with the large mitoribosomal subunit |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SLM1 |
YIL105C |
Phosphoinositide PI4,5P(2) binding protein, forms a complex with Slm2p |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RHO3 |
YIL118W |
Non-essential small GTPase of the Rho/Rac family of Ras-like proteins |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
QDR2 |
YIL121W |
Plasma membrane transporter of the major facilitator superfamily |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
REV7 |
YIL139C |
Accessory subunit of DNA polymerase zeta |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
IMP21 |
YIL154C |
Transcriptional activator involved in maintenance of ion homeostasis |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
UBP7 |
YIL156W |
Ubiquitin-specific protease that cleaves ubiquitin-protein fusions |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SEC11 |
YIR022W |
18kDa catalytic subunit of the Signal Peptidase Complex (SPC) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SYS1 |
YJL004C |
Integral membrane protein of the Golgi |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
LOH1 |
YJL038C |
Protein involved in outer spore wall assembly |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PEP8 |
YJL053W |
Vacuolar protein component of the retromer |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
LAS21 |
YJL062W |
Mannose-ethanolamine phosphotransferase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
JEM1 |
YJL073W |
DnaJ-like chaperone required for nuclear membrane fusion during mating |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YJL107C |
YJL107C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
NIT2 |
YJL126W |
Nit protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MRS3 |
YJL133W |
Iron transporter, mediates Fe2+ transport across inner mito membrane |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
LCB3 |
YJL134W |
Long-chain base-1-phosphate phosphatase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
VPS35 |
YJL154C |
Endosomal subunit of membrane-associated retromer complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SET2 |
YJL168C |
Histone methyltransferase with a role in transcriptional elongation |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
TOH1 |
YJL171C |
GPI-anchored cell wall protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SWI3 |
YJL176C |
Subunit of the SWI/SNF chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PFD1 |
YJL179W |
Subunit of heterohexameric prefoldin |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YJL193W |
YJL193W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RCY1 |
YJL204C |
F-box protein involved in recycling endocytosed proteins |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
TMA22 |
YJR014W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RAD7 |
YJR052W |
Nucleotide excision repair (NER) protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
KCH1 |
YJR054W |
Potassium transporter that mediates K+ influx |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
TOR1 |
YJR066W |
PIK-related protein kinase and rapamycin target |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
LIA1 |
YJR070C |
Deoxyhypusine hydroxylase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PXP2 |
YJR111C |
Peroxisomal matrix protein with naturally active promoter |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YJR142W |
YJR142W |
8-oxo-dGTP diphosphatase of the Nudix hydrolase family |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YKL033W-A |
YKL033W-A |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
VPS24 |
YKL041W |
One of four subunits of the ESCRT-III complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SPC42 |
YKL042W |
Central plaque component of spindle pole body (SPB) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PSG1 |
YKL077W |
Protein that promotes the transport and maturation of Pma1 with Exp1 |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
VPH2 |
YKL119C |
Integral membrane protein required for V-ATPase function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PEX1 |
YKL197C |
AAA-peroxin |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
TOR2 |
YKL203C |
PIK-related protein kinase and rapamycin target |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MRS4 |
YKR052C |
Iron transporter of the mitochondrial carrier family |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
KTR2 |
YKR061W |
Mannosyltransferase involved in N-linked protein glycosylation |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
TFA2 |
YKR062W |
TFIIE small subunit |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PTR2 |
YKR093W |
Integral membrane peptide transporter |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RTT109 |
YLL002W |
Histone acetyltransferase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SFI1 |
YLL003W |
Centrin (Cdc31p)-binding protein required for SPB duplication |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ORC3 |
YLL004W |
Subunit of the origin recognition complex (ORC) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SPA2 |
YLL021W |
Component of the polarisome |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YLL032C |
YLL032C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RPL8B |
YLL045C |
Ribosomal 60S subunit protein L8A |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YLR012C |
YLR012C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SDO1 |
YLR022C |
Guanine nucleotide exchange factor (GEF) for Ria1p |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SNF7 |
YLR025W |
One of four subunits of the ESCRT-III complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YLR031W |
YLR031W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
IES3 |
YLR052W |
Subunit of the INO80 chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SPT8 |
YLR055C |
Subunit of the SAGA transcriptional regulatory complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PER33 |
YLR064W |
Protein that localizes to the endoplasmic reticulum |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SIC1 |
YLR079W |
Cyclin-dependent kinase inhibitor (CKI) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
USB1 |
YLR132C |
Putative poly(U)-specific 3'-to-5' RNA exonuclease |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PUS5 |
YLR165C |
Pseudouridine synthase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MEC3 |
YLR288C |
DNA damage and meiotic pachytene checkpoint protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SEC72 |
YLR292C |
Non-essential subunit of Sec63 complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YHC1 |
YLR298C |
Component of the U1 snRNP complex required for pre-mRNA splicing |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
NKP2 |
YLR315W |
Central kinetochore protein and subunit of the Ctf19 complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
VRP1 |
YLR337C |
Verprolin, proline-rich actin-associated protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SPO77 |
YLR341W |
Meiosis-specific protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ORM2 |
YLR350W |
Protein that mediates sphingolipid homeostasis |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
NMD4 |
YLR363C |
Protein that may be involved in nonsense-mediated mRNA decay |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
VID22 |
YLR373C |
G-quadruplex (G4) DNA binding protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SEI1 |
YLR404W |
Seipin involved in lipid droplet (LD) assembly |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YLR407W |
YLR407W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
UTP21 |
YLR409C |
Subunit of U3-containing 90S preribosome and SSU processome complexes |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
NDC1 |
YML031W |
Subunit of the transmembrane ring of the nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YMD8 |
YML038C |
Putative nucleotide sugar transporter |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MFT1 |
YML062C |
Subunit of the THO complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YML079W |
YML079W |
Non-essential protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
NAB6 |
YML117W |
Putative RNA-binding protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
STB2 |
YMR053C |
Protein that interacts with Sin3p in a two-hybrid assay |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
STV1 |
YMR054W |
Subunit a of the vacuolar-ATPase V0 domain |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RIM9 |
YMR063W |
Plasma membrane protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SOV1 |
YMR066W |
Mitochondrial protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
IRC21 |
YMR073C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PDS5 |
YMR076C |
Cohesion maintenance factor |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SEC14 |
YMR079W |
Phosphatidylinositol/phosphatidylcholine transfer protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YMR099C |
YMR099C |
Glucose-6-phosphate 1-epimerase (hexose-6-phosphate mutarotase) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MGR3 |
YMR115W |
Subunit of the mitochondrial (mt) i-AAA protease supercomplex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SPT21 |
YMR179W |
Protein with a role in transcriptional silencing |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YMR206W |
YMR206W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
TRS130 |
YMR218C |
Component of transport protein particle (TRAPP) complex II |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
TAF7 |
YMR227C |
TFIID subunit (67 kDa) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
URA10 |
YMR271C |
Minor orotate phosphoribosyltransferase (OPRTase) isozyme |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RCE1 |
YMR274C |
Type II CAAX prenyl protease |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
JNM1 |
YMR294W |
Component of the yeast dynactin complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PRC1 |
YMR297W |
Vacuolar carboxypeptidase Y (proteinase C, CPY) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
UBP15 |
YMR304W |
Ubiquitin-specific protease involved in protein deubiquitination |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
IDP3 |
YNL009W |
Peroxisomal NADP-dependent isocitrate dehydrogenase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PBI2 |
YNL015W |
Cytosolic inhibitor of vacuolar proteinase B (PRB1) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RCM1 |
YNL022C |
rRNA m5C methyltransferase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YNL035C |
YNL035C |
Nuclear protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YNL108C |
YNL108C |
Protein phosphatase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
WHI3 |
YNL197C |
RNA binding protein that modulates mRNA stability |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
LAP3 |
YNL239W |
Cysteine aminopeptidase with homocysteine-thiolactonase activity |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
NRD1 |
YNL251C |
RNA-binding subunit of Nrd1 complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PDR17 |
YNL264C |
Phosphatidylinositol transfer protein (PITP) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
WSC2 |
YNL283C |
Sensor-transducer of the stress-activated PKC1-MPK1 signaling pathway |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RIM21 |
YNL294C |
pH sensor molecule, component of the RIM101 pathway |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
TRF5 |
YNL299W |
Non-canonical poly(A) polymerase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PFS2 |
YNL317W |
Integral subunit of the pre-mRNA CPF complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YNL320W |
YNL320W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
KRE1 |
YNL322C |
Cell wall glycoprotein involved in beta-glucan assembly |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YRF1-6 |
YNL339C |
Helicase encoded by the Y' element of subtelomeric regions |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
VPS27 |
YNR006W |
Endosomal protein that forms a complex with Hse1p |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
LRO1 |
YNR008W |
Acyltransferase that converts diacylglycerol to triacylglycerol (TGA) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
URK1 |
YNR012W |
Uridine/cytidine kinase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YNR014W |
YNR014W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YNR021W |
YNR021W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MRX15 |
YNR040W |
Membrane-associated mitoribosome receptor |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PET494 |
YNR045W |
Mitochondrial translational activator specific for the COX3 mRNA |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MNT4 |
YNR059W |
Putative alpha-1,3-mannosyltransferase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PFA4 |
YOL003C |
Palmitoyltransferase with autoacylation activity |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YOL013W-A |
YOL013W-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
TAT2 |
YOL020W |
High affinity tryptophan and tyrosine permease |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YOL024W |
YOL024W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YOL036W |
YOL036W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
NGL1 |
YOL042W |
Putative endonuclease |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PRS5 |
YOL061W |
5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MSH2 |
YOL090W |
Protein that binds to DNA mismatches |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SPO21 |
YOL091W |
Component of the meiotic outer plaque of the spindle pole body |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SHR5 |
YOL110W |
Palmitoyltransferase subunit |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MSB4 |
YOL112W |
GTPase-activating protein of the Ras superfamily |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SKM1 |
YOL113W |
Member of the PAK family of serine/threonine protein kinases |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YOL131W |
YOL131W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RAT1 |
YOR048C |
Nuclear 5' to 3' single-stranded RNA exonuclease |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
VAM10 |
YOR068C |
Protein involved in vacuole morphogenesis |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
VPS5 |
YOR069W |
Nexin-1 homolog |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SKI7 |
YOR076C |
GTP-binding protein that couples the Ski complex and exosome |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
VPS21 |
YOR089C |
Endosomal Rab family GTPase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
TRS33 |
YOR115C |
Core component of TRAPP complexes I, II and IV |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MED4 |
YOR174W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RET1 |
YOR207C |
Second-largest subunit of RNA polymerase III |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
TRE2 |
YOR256C |
Transferrin receptor-like protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MOD5 |
YOR274W |
Delta 2-isopentenyl pyrophosphate:tRNA isopentenyl transferase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RIM20 |
YOR275C |
Protein involved in proteolytic activation of Rim101p |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
TIM18 |
YOR297C |
Component of the mitochondrial TIM22 complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SLY41 |
YOR307C |
Protein involved in ER-to-Golgi transport |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SFG1 |
YOR315W |
Nuclear protein putative transcription factor |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SNX3 |
YOR357C |
Sorting nexin for late-Golgi enzymes |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PDE2 |
YOR360C |
High-affinity cyclic AMP phosphodiesterase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
NUD1 |
YOR373W |
Mitotic exit network (MEN) scaffold protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SNF8 |
YPL002C |
Component of the ESCRT-II complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
VPS28 |
YPL065W |
Component of the ESCRT-I complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YPL077C |
YPL077C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
VPS30 |
YPL120W |
Subunit of phosphatidylinositol (PtdIns) 3-kinase complexes I and II |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
KAP120 |
YPL125W |
Karyopherin responsible for the nuclear import of Rpf1p |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
TBF1 |
YPL128C |
Telobox-containing general regulatory factor |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PRM4 |
YPL156C |
Pheromone-regulated protein proposed to be involved in mating |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
OYE3 |
YPL171C |
Conserved NADPH oxidoreductase containing flavin mononucleotide (FMN) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SPT14 |
YPL175W |
UDP-glycosyltransferase subunit of the GPI-GnT complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
TCO89 |
YPL180W |
Subunit of TORC1 (Tor1p or Tor2p-Kog1p-Lst8p-Tco89p) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MF(ALPHA)1 |
YPL187W |
Mating pheromone alpha-factor, made by alpha cells |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YPL199C |
YPL199C |
Protein involved in nonstop mRNA decay |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
NIP7 |
YPL211W |
Nucleolar protein required for 60S ribosome subunit biogenesis |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SRP68 |
YPL243W |
Core component of the signal recognition particle (SRP) complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
HUT1 |
YPL244C |
Protein with a role in UDP-galactose transport to the Golgi lumen |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YPL257W |
YPL257W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PLC1 |
YPL268W |
Phospholipase C |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
KAR9 |
YPL269W |
Spindle positioning factor |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SRO7 |
YPR032W |
Effector of Rab GTPase Sec4p |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MAK3 |
YPR051W |
Catalytic subunit of the NatC type N-terminal acetyltransferase (NAT) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
NVJ2 |
YPR091C |
Lipid-binding ER protein, enriched at nucleus-vacuolar junctions (NVJ) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
NOC4 |
YPR144C |
Nucleolar protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YPR147C |
YPR147C |
Bifunctional triacylglycerol lipase and short chain ester hydrolase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RHO1 |
YPR165W |
GTP-binding protein of the rho subfamily of Ras-like proteins |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MKK1 |
YOR231W |
MAPKK involved in the protein kinase C signaling pathway |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
SSF1 |
YHR066W |
Constituent of 66S pre-ribosomal particles |
genetic |
1 |
1 |
1 |
Dosage Rescue |
HTL1 |
YCR020W-B |
Component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
HXT3 |
YDR345C |
Low affinity glucose transporter of the major facilitator superfamily |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
IAH1 |
YOR126C |
Isoamyl acetate-hydrolyzing esterase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
IES2 |
YNL215W |
Protein that associates with the INO80 chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ISW2 |
YOR304W |
ATP-dependent DNA translocase involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
TRS65 |
YGR166W |
Component of transport protein particle (TRAPP) complex II |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
LCB5 |
YLR260W |
Minor sphingoid long-chain base kinase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
LDB19 |
YOR322C |
Alpha-arrestin, Ub-ligase adaptor for Rsp5p |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MAP1 |
YLR244C |
Methionine aminopeptidase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MAS2 |
YHR024C |
Alpha subunit of the mitochondrial processing protease (MPP) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MLP2 |
YIL149C |
Myosin-like protein associated with the nuclear envelope |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MRT4 |
YKL009W |
Protein involved in mRNA turnover and ribosome assembly |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MSS2 |
YDL107W |
Peripherally bound inner membrane protein of the mitochondrial matrix |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
NAR1 |
YNL240C |
Subunit of the cytosolic iron-sulfur (FeS) protein assembly machinery |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
NCR1 |
YPL006W |
Vacuolar membrane protein involved with Npc2p in sterol trafficking |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
NDD1 |
YOR372C |
Transcriptional activator essential for nuclear division |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
NEJ1 |
YLR265C |
DNA end-binding protein required for nonhomologous end joining (NHEJ) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
NIP1 |
YMR309C |
eIF3c subunit of the eukaryotic translation initiation factor 3 (eIF3) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
NOC3 |
YLR002C |
Subunit of a nuclear complex with Noc2p and pre-replicative complexes |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
NOG1 |
YPL093W |
Putative GTPase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
NOP2 |
YNL061W |
rRNA m5C methyltransferase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
NOP9 |
YJL010C |
Essential subunit of U3-containing 90S preribosome |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
NSE3 |
YDR288W |
Component of the SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
NUP1 |
YOR098C |
FG-nucleoporin component of central core of the nuclear pore complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
NUP192 |
YJL039C |
Essential subunit of inner ring of nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
NUP85 |
YJR042W |
Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PAC11 |
YDR488C |
Dynein intermediate chain, microtubule motor protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PCS60 |
YBR222C |
Oxalyl-CoA synthetase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PDR16 |
YNL231C |
Phosphatidylinositol transfer protein (PITP) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PET100 |
YDR079W |
Chaperone that facilitates the assembly of cytochrome c oxidase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PHM6 |
YDR281C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
POP3 |
YNL282W |
Subunit of both RNase MRP and nuclear RNase P |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PRM5 |
YIL117C |
Pheromone-regulated protein, predicted to have 1 transmembrane segment |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PRM8 |
YGL053W |
Pheromone-regulated protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PRY3 |
YJL078C |
GPI-anchored cell wall protein involved in export of sterols |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PTI1 |
YGR156W |
Essential component of CPF (cleavage and polyadenylation factor) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RCK2 |
YLR248W |
Protein kinase involved in response to oxidative and osmotic stress |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
REI1 |
YBR267W |
Cytoplasmic pre-60S factor |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RGA2 |
YDR379W |
GTPase-activating protein for polarity-establishment protein Cdc42p |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RLP24 |
YLR009W |
Essential protein required for ribosomal large subunit biogenesis |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RNH202 |
YDR279W |
Ribonuclease H2 subunit |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ROG1 |
YGL144C |
Lipase with specificity for monoacylglycerol |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RPC19 |
YNL113W |
RNA polymerase subunit AC19 |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RPL19B |
YBL027W |
Ribosomal 60S subunit protein L19B |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RPL21B |
YPL079W |
Ribosomal 60S subunit protein L21B |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RPL36A |
YMR194W |
Ribosomal 60S subunit protein L36A |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RPS17B |
YDR447C |
Ribosomal protein 51 (rp51) of the small (40s) subunit |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RRD1 |
YIL153W |
Peptidyl-prolyl cis/trans-isomerase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RRP9 |
YPR137W |
Protein involved in pre-rRNA processing |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SCW11 |
YGL028C |
Cell wall protein with similarity to glucanases |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SIP1 |
YDR422C |
One of three alternate beta-subunits of the Snf1p kinase complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SLI15 |
YBR156C |
Subunit of the conserved chromosomal passenger complex (CPC) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SLN1 |
YIL147C |
Transmembrane histidine phosphotransfer kinase and osmosensor |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SOL1 |
YNR034W |
Protein with a possible role in tRNA export |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SPS19 |
YNL202W |
Peroxisomal 2,4-dienoyl-CoA reductase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SQS1 |
YNL224C |
Protein that stimulates the ATPase and helicase activities of Prp43p |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
STE14 |
YDR410C |
Farnesyl cysteine-carboxyl methyltransferase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SUI3 |
YPL237W |
Beta subunit of the translation initiation factor eIF2 |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SWI5 |
YDR146C |
Transcription factor that recruits Mediator and Swi/Snf complexes |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
TAF10 |
YDR167W |
Subunit (145 kDa) of TFIID and SAGA complexes |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
TAF14 |
YPL129W |
Subunit of TFIID, TFIIF, INO80, SWI/SNF, and NuA3 complexes |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
TAO3 |
YIL129C |
Component of the RAM signaling network |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
TAT1 |
YBR069C |
Amino acid transporter for valine, leucine, isoleucine, and tyrosine |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
TRM112 |
YNR046W |
Protein involved in methylation of tRNA, rRNA, and translation factors |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
UBC5 |
YDR059C |
Ubiquitin-conjugating enzyme |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
UGA2 |
YBR006W |
Succinate semialdehyde dehydrogenase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
UTP15 |
YMR093W |
Nucleolar protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
VHS2 |
YIL135C |
Regulator of septin dynamics |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
XBP1 |
YIL101C |
Transcriptional repressor |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YBR197C |
YBR197C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YBR219C |
YBR219C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YBR242W |
YBR242W |
5'-deoxynucleotidase involved in deoxyribonucleoside monophosphate deg |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YBR285W |
YBR285W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YCR050C |
YCR050C |
Non-essential protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YDL144C |
YDL144C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YDR124W |
YDR124W |
Mitochondrial protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YDR249C |
YDR249C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MGP12 |
YDR286C |
Mitochondrial protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YFH1 |
YDL120W |
Mitochondrial matrix iron chaperone |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YGP1 |
YNL160W |
Cell wall-related secretory glycoprotein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YHC3 |
YJL059W |
Protein required for the ATP-dependent transport of arginine |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SPS100 |
YHR139C |
Protein required for spore wall maturation |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YIH1 |
YCR059C |
Negative regulator of eIF2 kinase Gcn2p |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YIL165C |
YIL165C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YJL027C |
YJL027C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YKU70 |
YMR284W |
Subunit of the telomeric Ku complex (Yku70p-Yku80p) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YLR257W |
YLR257W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RTC4 |
YNL254C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YNR048W |
YNR048W |
Potential noncatalytic subunit for phospholipid translocase Dnf3p |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YPT11 |
YNL304W |
Rab GTPase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YPT35 |
YHR105W |
Endosomal protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YRO2 |
YBR054W |
Protein with a putative role in response to acid stress |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ZWF1 |
YNL241C |
Glucose-6-phosphate dehydrogenase (G6PD) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
TTI2 |
YJR136C |
Subunit of the ASTRA complex, involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Dosage Lethality |
RPC25 |
YKL144C |
RNA polymerase III subunit C25 |
genetic |
1 |
1 |
1 |
Positive Genetic |
PKC1 |
YBL105C |
Protein serine/threonine kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MSS4 |
YDR208W |
Phosphatidylinositol-4-phosphate 5-kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
NTF2 |
YER009W |
Nuclear envelope protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
TIM54 |
YJL054W |
Component of the mitochondrial TIM22 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
UGA3 |
YDL170W |
Transcriptional activator for GABA-dependent induction of GABA genes |
genetic |
1 |
1 |
1 |
Negative Genetic |
MPT5 |
YGL178W |
mRNA-binding protein of the PUF family |
genetic |
1 |
1 |
1 |
Negative Genetic |
SFB3 |
YHR098C |
Component of the Sec23p-Sfb3p heterodimer of the COPII vesicle coat |
genetic |
1 |
1 |
1 |
Negative Genetic |
YLR297W |
YLR297W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
PDR10 |
YOR328W |
ATP-binding cassette (ABC) transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
SSO2 |
YMR183C |
Plasma membrane t-SNARE |
genetic |
1 |
1 |
1 |
Negative Genetic |
TUB4 |
YLR212C |
Gamma-tubulin |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
DBP8 |
YHR169W |
ATPase, putative RNA helicase of the DEAD-box family |
physical |
1 |
1 |
1 |
Two-hybrid |
ESF2 |
YNR054C |
Essential nucleolar protein involved in pre-18S rRNA processing |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GCN20 |
YFR009W |
Positive regulator of the Gcn2p kinase activity |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GCN20 |
YFR009W |
Positive regulator of the Gcn2p kinase activity |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CPA2 |
YJR109C |
Large subunit of carbamoyl phosphate synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GPM1 |
YKL152C |
Tetrameric phosphoglycerate mutase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GPM1 |
YKL152C |
Tetrameric phosphoglycerate mutase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ADE57 |
YGL234W |
Bifunctional enzyme of 'de novo' purine nucleotide pathway |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
GPT2 |
YKR067W |
Glycerol-3-phosphate/dihydroxyacetone phosphate sn-1 acyltransferase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
FYV8 |
YGR196C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
DEP1 |
YAL013W |
Component of the Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
ADE3 |
YGR204W |
Cytoplasmic trifunctional enzyme |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CSE1 |
YGL238W |
Nuclear envelope protein that acts as a recycling factor |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
DUG1 |
YFR044C |
Cys-Gly metallo-di-peptidase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DUG1 |
YFR044C |
Cys-Gly metallo-di-peptidase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CCT2 |
YIL142W |
Subunit beta of the cytosolic chaperonin Cct ring complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CDC25 |
YLR310C |
Membrane bound guanine nucleotide exchange factor |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
HRK1 |
YOR267C |
Protein kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BSP1 |
YPR171W |
Adapter that links synaptojanins to the cortical actin cytoskeleton |
physical |
1 |
1 |
1 |
Two-hybrid |
GCN5 |
YGR252W |
Catalytic subunit of ADA and SAGA histone acetyltransferase complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
EFB1 |
YAL003W |
Translation elongation factor 1 beta |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BCY1 |
YIL033C |
Regulatory subunit of the cyclic AMP-dependent protein kinase (PKA) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BCK1 |
YJL095W |
MAPKKK acting in the protein kinase C signaling pathway |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
BRO1 |
YPL084W |
Cytoplasmic class E vacuolar protein sorting (VPS) factor |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
DRS2 |
YAL026C |
Trans-golgi network aminophospholipid translocase (flippase) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
HEK2 |
YBL032W |
RNA binding protein involved in asymmetric localization of ASH1 mRNA |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
BOI1 |
YBL085W |
Protein involved in polar growth, functionally redundant with Boi2p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GET3 |
YDL100C |
Guanine nucleotide exchange factor for Gpa1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GET3 |
YDL100C |
Guanine nucleotide exchange factor for Gpa1p |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
CMS1 |
YLR003C |
Putative subunit of the 90S preribosome processome complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ATP2 |
YJR121W |
Beta subunit of the F1 sector of mitochondrial F1F0 ATP synthase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
GET4 |
YOR164C |
Protein involved in inserting tail-anchored proteins into ER membranes |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
GPH1 |
YPR160W |
Glycogen phosphorylase required for the mobilization of glycogen |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DNM1 |
YLL001W |
Dynamin-related GTPase involved in mitochondrial organization |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ATP4 |
YPL078C |
Subunit b of the stator stalk of mitochondrial F1F0 ATP synthase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
EGD2 |
YHR193C |
Alpha subunit of the nascent polypeptide-associated complex (NAC) |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
ABP1 |
YCR088W |
Actin-binding protein of the cortical actin cytoskeleton |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CAR2 |
YLR438W |
L-ornithine transaminase (OTAse) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
GAS1 |
YMR307W |
Beta-1,3-glucanosyltransferase required for cell wall assembly |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GAS1 |
YMR307W |
Beta-1,3-glucanosyltransferase required for cell wall assembly |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
ACO1 |
YLR304C |
Aconitase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ADR1 |
YDR216W |
Carbon source-responsive zinc-finger transcription factor |
physical |
1 |
1 |
1 |
Two-hybrid |
CSR2 |
YPR030W |
Nuclear ubiquitin protein ligase binding protein |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
ADO1 |
YJR105W |
Adenosine kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ATG17 |
YLR423C |
Scaffold protein responsible for phagophore assembly site organization |
physical |
1 |
1 |
1 |
Two-hybrid |
GPP1 |
YIL053W |
Constitutively expressed DL-glycerol-3-phosphate phosphatase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DCS1 |
YLR270W |
Non-essential hydrolase involved in mRNA decapping |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ARF1 |
YDL192W |
ADP-ribosylation factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
AIM2 |
YAL049C |
Cytoplasmic protein involved in mitochondrial function or organization |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
BUB2 |
YMR055C |
Mitotic exit network regulator |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
AHP1 |
YLR109W |
Thiol-specific peroxiredoxin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CNA1 |
YLR433C |
Calcineurin A |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
DPS1 |
YLL018C |
Aspartyl-tRNA synthetase, primarily cytoplasmic |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
GSF2 |
YML048W |
Endoplasmic reticulum (ER) localized integral membrane protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
FAA4 |
YMR246W |
Long chain fatty acyl-CoA synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ARO4 |
YBR249C |
3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP) synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
APM3 |
YBR288C |
Mu3-like subunit of the clathrin associated protein complex (AP-3) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
GET1 |
YGL020C |
Subunit of the GET complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
GET2 |
YER083C |
Subunit of the GET complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
BOL2 |
YGL220W |
Cytosolic protein involved in repression of iron regulon transcription |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
BFA1 |
YJR053W |
Subunit of a two-component GTPase-activating protein, Bfa1p-Bub2p |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CMK1 |
YFR014C |
Calmodulin-dependent protein kinase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CCT5 |
YJR064W |
Subunit of the cytosolic chaperonin Cct ring complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CCT5 |
YJR064W |
Subunit of the cytosolic chaperonin Cct ring complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
EGD1 |
YPL037C |
Subunit beta1 of the nascent polypeptide-associated complex (NAC) |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
AMF1 |
YOR378W |
Low affinity NH4+ transporter |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ADK1 |
YDR226W |
Adenylate kinase, required for purine metabolism |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ADK1 |
YDR226W |
Adenylate kinase, required for purine metabolism |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
COF1 |
YLL050C |
Cofilin, involved in pH-dependent actin filament depolarization |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
COF1 |
YLL050C |
Cofilin, involved in pH-dependent actin filament depolarization |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
GPD2 |
YOL059W |
NAD-dependent glycerol 3-phosphate dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GPD2 |
YOL059W |
NAD-dependent glycerol 3-phosphate dehydrogenase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
GPD1 |
YDL022W |
NAD-dependent glycerol-3-phosphate dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ATG12 |
YBR217W |
Ubiquitin-like modifier involved in autophagy and the Cvt pathway |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
HSP104 |
YLL026W |
Disaggregase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ATG42 |
YBR139W |
Vacuolar serine-type carboxypeptidase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CYC8 |
YBR112C |
General transcriptional co-repressor |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ARG4 |
YHR018C |
Argininosuccinate lyase |
physical |
1 |
1 |
1 |
Two-hybrid |
AYR1 |
YIL124W |
Bifunctional triacylglycerol lipase and 1-acyl DHAP reductase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
AYR1 |
YIL124W |
Bifunctional triacylglycerol lipase and 1-acyl DHAP reductase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
DYN2 |
YDR424C |
Cytoplasmic light chain dynein, microtubule motor protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
DSS1 |
YMR287C |
3'-5' exoribonuclease |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
APT1 |
YML022W |
Adenine phosphoribosyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ERG10 |
YPL028W |
Acetyl-CoA C-acetyltransferase (acetoacetyl-CoA thiolase) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
FUM1 |
YPL262W |
Fumarase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CCT3 |
YJL014W |
Subunit of the cytosolic chaperonin Cct ring complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HEM15 |
YOR176W |
Ferrochelatase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ERG1 |
YGR175C |
Squalene epoxidase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ELM1 |
YKL048C |
Serine/threonine protein kinase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
ADH3 |
YMR083W |
Mitochondrial alcohol dehydrogenase isozyme III |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ADH3 |
YMR083W |
Mitochondrial alcohol dehydrogenase isozyme III |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ARE2 |
YNR019W |
Acyl-CoA:sterol acyltransferase |
physical |
1 |
1 |
1 |
Two-hybrid |
BUL1 |
YMR275C |
Alpha-arrestin, component of the Rsp5p E3-ubiquitin ligase complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HSL7 |
YBR133C |
Protein arginine N-methyltransferase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CDC60 |
YPL160W |
Cytosolic leucyl tRNA synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GRS1 |
YBR121C |
Cytoplasmic and mitochondrial glycyl-tRNA synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ERG20 |
YJL167W |
Farnesyl pyrophosphate synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CDC37 |
YDR168W |
Essential Hsp90p co-chaperone |
genetic |
1 |
1 |
1 |
Dosage Rescue |
EST1 |
YLR233C |
TLC1 RNA-associated factor involved in telomere length regulation |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
EST1 |
YLR233C |
TLC1 RNA-associated factor involved in telomere length regulation |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
HOM6 |
YJR139C |
Homoserine dehydrogenase (L-homoserine:NADP oxidoreductase) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HOM6 |
YJR139C |
Homoserine dehydrogenase (L-homoserine:NADP oxidoreductase) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CDC4 |
YFL009W |
F-box protein required for both the G1/S and G2/M phase transitions |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ERG6 |
YML008C |
Delta(24)-sterol C-methyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GRX1 |
YCL035C |
Glutathione-dependent disulfide oxidoreductase |
physical |
1 |
1 |
1 |
Two-hybrid |
CTF13 |
YMR094W |
Subunit of the CBF3 complex |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
CTF13 |
YMR094W |
Subunit of the CBF3 complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ADD66 |
YKL206C |
Protein involved in 20S proteasome assembly |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
BEM3 |
YPL115C |
Rho GTPase activating protein (RhoGAP) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CIN8 |
YEL061C |
Bipolar kinesin motor protein |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
GAL7 |
YBR018C |
Galactose-1-phosphate uridyl transferase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CDC15 |
YAR019C |
Hippo-like kinase of the Mitotic Exit Network |
physical |
1 |
1 |
1 |
Two-hybrid |
GPG1 |
YGL121C |
Proposed gamma subunit of the heterotrimeric G protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ARE1 |
YCR048W |
Acyl-CoA:sterol acyltransferase |
physical |
1 |
1 |
1 |
Two-hybrid |
HOG1 |
YLR113W |
Mitogen-activated protein kinase involved in osmoregulation |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
HIR2 |
YOR038C |
Subunit of HIR nucleosome assembly complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
FAA1 |
YOR317W |
Long chain fatty acyl-CoA synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ACS1 |
YAL054C |
Acetyl-coA synthetase isoform |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ADE17 |
YMR120C |
Enzyme of 'de novo' purine biosynthesis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
AIP5 |
YFR016C |
Protein that positively regulates actin assembly |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CTF4 |
YPR135W |
Chromatin-associated protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HOM3 |
YER052C |
Aspartate kinase (L-aspartate 4-P-transferase) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CCE1 |
YKL011C |
Mitochondrial cruciform cutting endonuclease |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
FPK1 |
YNR047W |
Ser/Thr protein kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
EPT1 |
YHR123W |
sn-1,2-diacylglycerol ethanolamine- and cholinephosphotranferase |
physical |
1 |
1 |
1 |
Two-hybrid |
CLB2 |
YPR119W |
B-type cyclin involved in cell cycle progression |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
GSY1 |
YFR015C |
Glycogen synthase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
APA1 |
YCL050C |
AP4A phosphorylase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GDT1 |
YBR187W |
Calcium and manganese transporter with higher affinity for Ca2+ |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CTR1 |
YPR124W |
High-affinity copper transporter of plasma membrane |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
DUT1 |
YBR252W |
Deoxyuridine triphosphate diphosphatase (dUTPase) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
DBF2 |
YGR092W |
Ser/Thr kinase involved in transcription and stress response |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
DUF1 |
YOL087C |
Ubiquitin-binding protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CBR1 |
YIL043C |
Cytochrome b reductase and NADH-dependent reductase for Dph3p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CSC1 |
YLR241W |
Calcium permeable gated cation channel |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ARA1 |
YBR149W |
NADP+ dependent arabinose dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ADE6 |
YGR061C |
Formylglycinamidine-ribonucleotide (FGAM)-synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HOM2 |
YDR158W |
Aspartic beta semi-aldehyde dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CDH1 |
YGL003C |
Activator of anaphase-promoting complex/cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
CMG1 |
YLR271W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ARO9 |
YHR137W |
Aromatic aminotransferase II |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
GDH2 |
YDL215C |
NAD(+)-dependent glutamate dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GDH2 |
YDL215C |
NAD(+)-dependent glutamate dehydrogenase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
AFG3 |
YER017C |
Mitochondrial inner membrane m-AAA protease component |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
APL4 |
YPR029C |
Gamma-adaptin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ATP5 |
YDR298C |
Subunit 5 of the stator stalk of mitochondrial F1F0 ATP synthase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
CSM2 |
YIL132C |
Subunit of the Shu complex (aka PCSS complex) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
BUD27 |
YFL023W |
Unconventional prefoldin protein involved in translation initiation |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
ARP1 |
YHR129C |
Actin-related protein of the dynactin complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ADE2 |
YOR128C |
Phosphoribosylaminoimidazole carboxylase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CLN3 |
YAL040C |
G1 cyclin involved in cell cycle progression |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CSM1 |
YCR086W |
Nucleolar protein that mediates homolog segregation during meiosis I |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
DAL82 |
YNL314W |
Positive regulator of allophanate inducible genes |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
GDH1 |
YOR375C |
NADP(+)-dependent glutamate dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ARG81 |
YML099C |
Zinc finger transcription factor involved in arginine-responsive genes |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
GRX5 |
YPL059W |
Glutathione-dependent oxidoreductase |
physical |
1 |
1 |
1 |
Two-hybrid |
HSP10 |
YOR020C |
Mitochondrial matrix co-chaperonin |
physical |
1 |
1 |
1 |
Two-hybrid |
ALY2 |
YJL084C |
Alpha arrestin, Ub-ligase adaptor for Rsp5p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ATG36 |
YJL185C |
Pex3p interacting protein, required for pexophagy |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
DON1 |
YDR273W |
Meiosis-specific component of the spindle pole body |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
AIM3 |
YBR108W |
Protein that inhibits barbed-end actin filament elongation |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
BAS1 |
YKR099W |
Myb-related transcription factor |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
ECI1 |
YLR284C |
Peroxisomal delta3,delta2-enoyl-CoA isomerase |
physical |
1 |
1 |
1 |
Two-hybrid |
CHA4 |
YLR098C |
DNA binding transcriptional activator |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
ADY3 |
YDL239C |
Protein required for spore wall formation |
physical |
1 |
1 |
1 |
Two-hybrid |
ADY3 |
YDL239C |
Protein required for spore wall formation |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
DET1 |
YDR051C |
Acid phosphatase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CNL1 |
YDR357C |
Subunit of the BLOC-1 complex involved in endosomal maturation |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ASK10 |
YGR097W |
Regulator of the Fps1p glycerol channel |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BOS1 |
YLR078C |
v-SNARE (vesicle specific SNAP receptor) |
physical |
1 |
1 |
1 |
Two-hybrid |
CWC15 |
YDR163W |
Non-essential protein involved in pre-mRNA splicing |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
COG7 |
YGL005C |
Component of the conserved oligomeric Golgi complex |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
COG7 |
YGL005C |
Component of the conserved oligomeric Golgi complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
COG5 |
YNL051W |
Component of the conserved oligomeric Golgi complex |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
COG5 |
YNL051W |
Component of the conserved oligomeric Golgi complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
GIP3 |
YPL137C |
Cytoplasmic protein that regulates protein phosphatase 1 Glc7p |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
AMD1 |
YML035C |
AMP deaminase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CDC31 |
YOR257W |
Calcium-binding component of the spindle pole body (SPB) half-bridge |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
HPC2 |
YBR215W |
Subunit of the HIR complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CSE4 |
YKL049C |
Centromeric histone H3-like protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ALF1 |
YNL148C |
Alpha-tubulin folding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BFR1 |
YOR198C |
Component of mRNP complexes associated with polyribosomes |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
BFR1 |
YOR198C |
Component of mRNP complexes associated with polyribosomes |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CTK2 |
YJL006C |
Beta subunit of C-terminal domain kinase I (CTDK-I) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DBP5 |
YOR046C |
Cytoplasmic ATP-dependent RNA helicase of the DEAD-box family |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DBP5 |
YOR046C |
Cytoplasmic ATP-dependent RNA helicase of the DEAD-box family |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ELO2 |
YCR034W |
Fatty acid elongase, involved in sphingolipid biosynthesis |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
EPS1 |
YIL005W |
ER protein with chaperone and co-chaperone activity |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
EXO1 |
YOR033C |
5'-3' exonuclease and flap-endonuclease |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ECO1 |
YFR027W |
Acetyltransferase required for sister chromatid cohesion |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
HNT1 |
YDL125C |
Adenosine 5'-monophosphoramidase |
physical |
1 |
1 |
1 |
Two-hybrid |
HNT1 |
YDL125C |
Adenosine 5'-monophosphoramidase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
HOP2 |
YGL033W |
Meiosis-specific protein that localizes to chromosomes |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
ATS1 |
YAL020C |
Protein required for modification of wobble nucleosides in tRNA |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
DPH2 |
YKL191W |
Protein required for synthesis of diphthamide |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
HRB1 |
YNL004W |
Poly(A+) RNA-binding protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CIN1 |
YOR349W |
Tubulin folding factor D involved in beta-tubulin (Tub2p) folding |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
HSF1 |
YGL073W |
Trimeric heat shock transcription factor |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
EMP47 |
YFL048C |
Integral membrane component of ER-derived COPII-coated vesicles |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
GLN3 |
YER040W |
Transcriptional activator in nitrogen catabolite repression system |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
GAL10 |
YBR019C |
UDP-glucose-4-epimerase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
ERV46 |
YAL042W |
Protein localized to COPII-coated vesicles |
physical |
1 |
1 |
1 |
Two-hybrid |
CSG2 |
YBR036C |
Endoplasmic reticulum membrane protein |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
CCP1 |
YKR066C |
Mitochondrial cytochrome-c peroxidase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BUD2 |
YKL092C |
GTPase activating factor for Rsr1p/Bud1p |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
GYP1 |
YOR070C |
Cis-golgi GTPase-activating protein (GAP) for yeast Rabs |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CCS1 |
YMR038C |
Copper chaperone for superoxide dismutase Sod1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BNR1 |
YIL159W |
Formin |
physical |
1 |
1 |
1 |
Two-hybrid |
BNR1 |
YIL159W |
Formin |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
FCP1 |
YMR277W |
Carboxy-terminal domain (CTD) phosphatase |
physical |
1 |
1 |
1 |
Two-hybrid |
FCP1 |
YMR277W |
Carboxy-terminal domain (CTD) phosphatase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
EMC5 |
YIL027C |
Member of conserved ER transmembrane complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ARG80 |
YMR042W |
Transcription factor involved in regulating arginine-responsive genes |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ESC1 |
YMR219W |
Protein involved in telomeric silencing |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ESC2 |
YDR363W |
Sumo-like domain protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
GAL1 |
YBR020W |
Galactokinase |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
CAD1 |
YDR423C |
AP-1-like basic leucine zipper (bZIP) transcriptional activator |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
AKR1 |
YDR264C |
Palmitoyl transferase involved in protein palmitoylation |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
BCH1 |
YMR237W |
Member of the ChAPs family (Chs5p-Arf1p-binding proteins) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
FBP26 |
YJL155C |
Fructose-2,6-bisphosphatase, required for glucose metabolism |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
EMA17 |
YIL029C |
Protein involved in targeting mitochondrial membrane protein precursor |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
COQ1 |
YBR003W |
Hexaprenyl pyrophosphate synthetase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
DPH6 |
YLR143W |
Diphthamide synthetase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
GPR1 |
YDL035C |
Plasma membrane G protein coupled receptor (GPCR) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
GYL1 |
YMR192W |
Putative GTPase activating protein (GAP) with a role in exocytosis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GFD2 |
YCL036W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CLA4 |
YNL298W |
Cdc42p-activated signal transducing kinase |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
CHS5 |
YLR330W |
Component of the exomer complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
HMS1 |
YOR032C |
bHLH protein with similarity to myc-family transcription factors |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
GTT1 |
YIR038C |
ER associated glutathione S-transferase |
physical |
1 |
1 |
1 |
Two-hybrid |
ALG5 |
YPL227C |
UDP-glucose:dolichyl-phosphate glucosyltransferase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
GAT1 |
YFL021W |
Transcriptional activator of nitrogen catabolite repression genes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GAT1 |
YFL021W |
Transcriptional activator of nitrogen catabolite repression genes |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
APN2 |
YBL019W |
Class II abasic (AP) endonuclease involved in repair of DNA damage |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
COX17 |
YLL009C |
Copper metallochaperone that transfers copper to Sco1p and Cox11p |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
HRD1 |
YOL013C |
Ubiquitin-protein ligase involved in ER-associated degradation (ERAD) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HRD1 |
YOL013C |
Ubiquitin-protein ligase involved in ER-associated degradation (ERAD) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
BSD2 |
YBR290W |
Heavy metal ion homeostasis protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
GGA1 |
YDR358W |
Golgi-localized protein with homology to gamma-adaptin |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
HOC1 |
YJR075W |
Alpha-1,6-mannosyltransferase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
CAP2 |
YIL034C |
Beta subunit of the capping protein heterodimer (Cap1p and Cap2p) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ETT1 |
YOR051C |
Nuclear protein that inhibits replication of Brome mosaic virus |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HAC1 |
YFL031W |
Basic leucine zipper (bZIP) transcription factor (ATF/CREB1 homolog) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ARL3 |
YPL051W |
ARF-like small GTPase of the RAS superfamily |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
HBT1 |
YDL223C |
Shmoo tip protein, substrate of Hub1p ubiquitin-like protein |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
DBP6 |
YNR038W |
Essential protein involved in ribosome biogenesis |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
DYS1 |
YHR068W |
Deoxyhypusine synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ERV14 |
YGL054C |
COPII-coated vesicle protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CLB3 |
YDL155W |
B-type cyclin involved in cell cycle progression |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
AQR1 |
YNL065W |
Plasma membrane transporter of the major facilitator superfamily |
physical |
1 |
1 |
1 |
Two-hybrid |
EAF7 |
YNL136W |
Subunit of the NuA4 histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
ERG28 |
YER044C |
Endoplasmic reticulum membrane protein |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
ASG1 |
YIL130W |
Zinc cluster protein proposed to be a transcriptional regulator |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
DPM1 |
YPR183W |
Dolichol phosphate mannose (Dol-P-Man) synthase of ER membrane |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DPM1 |
YPR183W |
Dolichol phosphate mannose (Dol-P-Man) synthase of ER membrane |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ERG5 |
YMR015C |
C-22 sterol desaturase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
EUC1 |
YMR111C |
Sequence-specific DNA binding protein |
physical |
1 |
1 |
1 |
Two-hybrid |
ARO8 |
YGL202W |
Aromatic aminotransferase I |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
EMC6 |
YLL014W |
Member of conserved ER transmembrane complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
AUS1 |
YOR011W |
Plasma membrane sterol transporter of the ATP-binding cassette family |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BUG1 |
YDL099W |
Cis-golgi localized protein involved in ER to Golgi transport |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
HSP26 |
YBR072W |
Small heat shock protein (sHSP) with chaperone activity |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CPS1 |
YJL172W |
Vacuolar carboxypeptidase S |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
CIT1 |
YNR001C |
Mitochondrial citrate synthase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CAT2 |
YML042W |
Carnitine acetyl-CoA transferase |
physical |
1 |
1 |
1 |
Two-hybrid |
ADE1 |
YAR015W |
N-succinyl-5-aminoimidazole-4-carboxamide ribotide synthetase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
HCM1 |
YCR065W |
Forkhead transcription factor |
physical |
1 |
1 |
1 |
Two-hybrid |
ASF2 |
YDL197C |
Anti-silencing protein |
physical |
1 |
1 |
1 |
Two-hybrid |
ASF2 |
YDL197C |
Anti-silencing protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CBS2 |
YDR197W |
Mitochondrial translational activator of the COB mRNA |
physical |
1 |
1 |
1 |
Two-hybrid |
EXG2 |
YDR261C |
Exo-1,3-beta-glucanase |
physical |
1 |
1 |
1 |
Two-hybrid |
EXG2 |
YDR261C |
Exo-1,3-beta-glucanase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
FMO1 |
YHR176W |
Flavin-containing monooxygenase |
physical |
1 |
1 |
1 |
Two-hybrid |
FMO1 |
YHR176W |
Flavin-containing monooxygenase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
EMP70 |
YLR083C |
Protein with a role in cellular adhesion and filamentous growth |
physical |
1 |
1 |
1 |
Two-hybrid |
COQ9 |
YLR201C |
Protein required for ubiquinone biosynthesis and respiratory growth |
physical |
1 |
1 |
1 |
Two-hybrid |
ATF1 |
YOR377W |
Alcohol acetyltransferase |
physical |
1 |
1 |
1 |
Two-hybrid |
BTS1 |
YPL069C |
Geranylgeranyl diphosphate synthase (GGPPS) |
physical |
1 |
1 |
1 |
Two-hybrid |
FRK1 |
YPL141C |
Protein kinase of unknown cellular role |
physical |
1 |
1 |
1 |
Two-hybrid |
FRK1 |
YPL141C |
Protein kinase of unknown cellular role |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
HLR1 |
YDR528W |
Protein involved in regulation of cell wall composition and integrity |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HNM1 |
YGL077C |
Plasma membrane transporter for choline, ethanolamine, and carnitine |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GEF1 |
YJR040W |
Voltage-gated chloride channel |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GEF1 |
YJR040W |
Voltage-gated chloride channel |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CSF1 |
YLR087C |
Protein with structural similarity to lipid transport protein Vps13p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CUE4 |
YML101C |
Protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BUD22 |
YMR014W |
Protein required for rRNA maturation and ribosomal subunit biogenesis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
COQ3 |
YOL096C |
O-methyltransferase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ASG7 |
YJL170C |
Protein that regulates signaling from G protein beta subunit Ste4p |
physical |
1 |
1 |
1 |
Two-hybrid |
ASG7 |
YJL170C |
Protein that regulates signaling from G protein beta subunit Ste4p |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
DUS3 |
YLR401C |
Dihydrouridine synthase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
BCH2 |
YKR027W |
Member of the ChAPs (Chs5p-Arf1p-binding proteins) family |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
CST26 |
YBR042C |
Acyltransferase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
HEH2 |
YDR458C |
Inner nuclear membrane (INM) protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CAN1 |
YEL063C |
Plasma membrane arginine permease |
physical |
1 |
1 |
1 |
Two-hybrid |
CAN1 |
YEL063C |
Plasma membrane arginine permease |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
AIM45 |
YPR004C |
Putative ortholog of mammalian ETF-alpha |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ERG2 |
YMR202W |
C-8 sterol isomerase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
DDR2 |
YOL052C-A |
Multi-stress response protein |
physical |
1 |
1 |
1 |
Two-hybrid |
AGP2 |
YBR132C |
Plasma membrane regulator of polyamine and carnitine transport |
physical |
1 |
1 |
1 |
Two-hybrid |
AVT6 |
YER119C |
Vacuolar aspartate and glutamate exporter |
physical |
1 |
1 |
1 |
Two-hybrid |
BAP3 |
YDR046C |
Amino acid permease |
physical |
1 |
1 |
1 |
Two-hybrid |
BSC6 |
YOL137W |
Protein of unknown function with 8 putative transmembrane segments |
physical |
1 |
1 |
1 |
Two-hybrid |
DAL5 |
YJR152W |
Allantoate permease |
physical |
1 |
1 |
1 |
Two-hybrid |
ESBP6 |
YNL125C |
Protein with similarity to monocarboxylate permeases |
physical |
1 |
1 |
1 |
Two-hybrid |
FUN26 |
YAL022C |
High affinity, broad selectivity, nucleoside/nucleobase transporter |
physical |
1 |
1 |
1 |
Two-hybrid |
CFD1 |
YIL003W |
Highly conserved iron-sulfur cluster binding protein |
physical |
1 |
1 |
1 |
Two-hybrid |
GDA1 |
YEL042W |
Guanosine diphosphatase located in the Golgi |
physical |
1 |
1 |
1 |
Two-hybrid |
HAM1 |
YJR069C |
Nucleoside triphosphate pyrophosphohydrolase |
physical |
1 |
1 |
1 |
Two-hybrid |
ANT1 |
YPR128C |
Peroxisomal adenine nucleotide transporter |
physical |
1 |
1 |
1 |
Two-hybrid |
GPI2 |
YPL076W |
Protein involved in the synthesis of GlcNAc-PI |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CUE1 |
YMR264W |
Ubiquitin-binding protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
HSP12 |
YFL014W |
Plasma membrane protein involved in maintaining membrane organization |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GLK1 |
YCL040W |
Glucokinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
AYT1 |
YLL063C |
Acetyltransferase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ARI1 |
YGL157W |
NADPH-dependent aldehyde reductase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
FRE3 |
YOR381W |
Ferric reductase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
FCF2 |
YLR051C |
Nucleolar protein involved in the early steps of 35S rRNA processing |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
AIM22 |
YJL046W |
Lipoate-protein ligase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
AEP3 |
YPL005W |
Peripheral mitochondrial inner membrane protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
GRX4 |
YER174C |
Glutathione-dependent oxidoreductase and glutathione S-transferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CRS1 |
YNL247W |
Cysteinyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CUE3 |
YGL110C |
Subunit of ribosome-associated quality control trigger complex (RQT) |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
ATG32 |
YIL146C |
Mitochondrial outer membrane protein required to initiate mitophagy |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
FIG2 |
YCR089W |
Cell wall adhesin, expressed specifically during mating |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
CSR1 |
YLR380W |
Phosphatidylinositol transfer protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CHA1 |
YCL064C |
Catabolic L-serine (L-threonine) deaminase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GRE3 |
YHR104W |
Aldose reductase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ALD6 |
YPL061W |
Cytosolic aldehyde dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ETR1 |
YBR026C |
2-enoyl thioester reductase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CYB5 |
YNL111C |
Cytochrome b5 |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CTP1 |
YBR291C |
Mitochondrial inner membrane citrate transporter |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ANB1 |
YJR047C |
Translation elongation factor eIF-5A |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CYK3 |
YDL117W |
SH3-domain protein located in the bud neck and cytokinetic actin ring |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CAJ1 |
YER048C |
Nuclear type II J heat shock protein of the E. coli dnaJ family |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ECM3 |
YOR092W |
Non-essential protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
HFD1 |
YMR110C |
Dehydrogenase involved in ubiquinone and sphingolipid metabolism |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
EFM6 |
YNL024C |
Putative S-adenosylmethionine-dependent lysine methyltransferase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ADE12 |
YNL220W |
Adenylosuccinate synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GIS2 |
YNL255C |
Translational activator for mRNAs with internal ribosome entry sites |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
GTT3 |
YEL017W |
Protein of unknown function may be involved in glutathione metabolism |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
GIP4 |
YAL031C |
Cytoplasmic protein that regulates protein phosphatase 1 Glc7p |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
DNF1 |
YER166W |
Aminophospholipid translocase (flippase) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
GLN4 |
YOR168W |
Glutamine tRNA synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CUP9 |
YPL177C |
Homeodomain-containing transcriptional repressor |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
FAS1 |
YKL182W |
Beta subunit of fatty acid synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GEP5 |
YLR091W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
GVP36 |
YIL041W |
BAR domain protein that localizes to early and late Golgi vesicles |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GVP36 |
YIL041W |
BAR domain protein that localizes to early and late Golgi vesicles |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
BST1 |
YFL025C |
GPI inositol deacylase of the endoplasmic reticulum (ER) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ABP140 |
YOR239W |
AdoMet-dependent tRNA methyltransferase and actin binding protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ALR2 |
YFL050C |
Probable Mg(2+) transporter |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CMK2 |
YOL016C |
Calmodulin-dependent protein kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ARV1 |
YLR242C |
Cortical ER protein |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
DFM1 |
YDR411C |
Endoplasmic reticulum (ER) localized protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
DEG1 |
YFL001W |
tRNA:pseudouridine synthase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
FPS1 |
YLL043W |
Aquaglyceroporin, plasma membrane channel |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
AGE2 |
YIL044C |
ADP-ribosylation factor (ARF) GTPase activating protein (GAP) effector |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CYC3 |
YAL039C |
Cytochrome c heme lyase (holocytochrome c synthase) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ENT4 |
YLL038C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
HIS5 |
YIL116W |
Histidinol-phosphate aminotransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GUP1 |
YGL084C |
Plasma membrane protein involved in remodeling GPI anchors |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
GAS3 |
YMR215W |
Putative 1,3-beta-glucanosyltransferase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
AAD4 |
YDL243C |
Putative aryl-alcohol dehydrogenase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
COX10 |
YPL172C |
Heme A:farnesyltransferase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CYT1 |
YOR065W |
Cytochrome c1 |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
ALG13 |
YGL047W |
Catalytic component of UDP-GlcNAc transferase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CDC50 |
YCR094W |
Endosomal protein that interacts with phospholipid flippase Drs2p |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
EST2 |
YLR318W |
Reverse transcriptase subunit of the telomerase holoenzyme |
physical |
1 |
1 |
1 |
Co-localization |
ASI1 |
YMR119W |
Subunit of the inner nuclear membrane Asi ubiquitin ligase complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
HPA3 |
YEL066W |
D-Amino acid N-acetyltransferase that detoxifies D-amino acids |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
HEM2 |
YGL040C |
Aminolevulinate dehydratase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
COQ2 |
YNR041C |
Para hydroxybenzoate polyprenyl transferase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
CYC2 |
YOR037W |
Mitochondrial peripheral inner membrane protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
BXI1 |
YNL305C |
Protein involved in apoptosis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BXI1 |
YNL305C |
Protein involved in apoptosis |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
AST2 |
YER101C |
Lipid raft associated protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
COA1 |
YIL157C |
Mitochondrial inner membrane protein |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
DFG16 |
YOR030W |
Probable multiple transmembrane protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
FPY1 |
YMR178W |
FAD pyrophosphatase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
AIM34 |
YMR003W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
GPX2 |
YBR244W |
Phospholipid hydroperoxide glutathione peroxidase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GRX3 |
YDR098C |
Glutathione-dependent oxidoreductase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BAP2 |
YBR068C |
High-affinity leucine permease |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
FCY2 |
YER056C |
Purine-cytosine permease |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
DPP1 |
YDR284C |
Diacylglycerol pyrophosphate (DGPP) phosphatase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GPM2 |
YDL021W |
Nonfunctional homolog of Gpm1p phosphoglycerate mutase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
HNT2 |
YDR305C |
Dinucleoside triphosphate hydrolase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ARO10 |
YDR380W |
Phenylpyruvate decarboxylase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HLJ1 |
YMR161W |
Co-chaperone for Hsp40p |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CHO2 |
YGR157W |
Phosphatidylethanolamine methyltransferase (PEMT) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
COX23 |
YHR116W |
Protein that functions in mitochondrial copper homeostasis |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
GPI13 |
YLL031C |
ER membrane localized phosphoryltransferase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CCW12 |
YLR110C |
Cell wall mannoprotein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
DAL2 |
YIR029W |
Allantoicase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
CDS1 |
YBR029C |
Phosphatidate cytidylyltransferase (CDP-diglyceride synthetase) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CTT1 |
YGR088W |
Cytosolic catalase T |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ATG15 |
YCR068W |
Phospholipase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
HAL9 |
YOL089C |
Putative transcription factor containing a zinc finger |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
GRX2 |
YDR513W |
Cytoplasmic glutaredoxin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DAK1 |
YML070W |
Dihydroxyacetone kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CCW14 |
YLR390W-A |
Covalently linked cell wall glycoprotein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
DAT1 |
YML113W |
DNA binding protein that recognizes oligo(dA).oligo(dT) tracts |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CTS1 |
YLR286C |
Endochitinase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
GPI18 |
YBR004C |
Functional ortholog of human PIG-V |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
EMI1 |
YDR512C |
Non-essential protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
BRE4 |
YDL231C |
Zinc finger protein containing five transmembrane domains |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
AFT2 |
YPL202C |
Iron-regulated transcriptional activator |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
DLD1 |
YDL174C |
Major mitochondrial D-lactate dehydrogenase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
COX9 |
YDL067C |
Subunit VIIa of cytochrome c oxidase (Complex IV) |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
GIS3 |
YLR094C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
HSP78 |
YDR258C |
Oligomeric mitochondrial matrix chaperone |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GRE2 |
YOL151W |
3-methylbutanal reductase and NADPH-dependent methylglyoxal reductase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HIS1 |
YER055C |
ATP phosphoribosyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ERG9 |
YHR190W |
Farnesyl-diphosphate farnesyl transferase (squalene synthase) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
AIM32 |
YML050W |
2Fe-2S mitochondrial protein involved in redox quality control |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GRX6 |
YDL010W |
Cis-Golgi localized monothiol glutaredoxin, binds Fe-S cluster |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CRD1 |
YDL142C |
Cardiolipin synthase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
GPI15 |
YNL038W |
Protein involved in the synthesis of GlcNAc-PI |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
EFM4 |
YIL064W |
Lysine methyltransferase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CPR8 |
YNR028W |
Peptidyl-prolyl cis-trans isomerase (cyclophilin) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
APS3 |
YJL024C |
Small subunit of the clathrin-associated adaptor complex AP-3 |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
DIT2 |
YDR402C |
N-formyltyrosine oxidase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ALD3 |
YMR169C |
Cytoplasmic aldehyde dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GUP2 |
YPL189W |
Probable membrane protein |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
FEN2 |
YCR028C |
Plasma membrane H+-pantothenate symporter |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
GIT1 |
YCR098C |
Plasma membrane permease |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
DGK1 |
YOR311C |
Diacylglycerol kinase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
COA6 |
YMR244C-A |
Protein involved in cytochrome c oxidase (Complex IV) assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERJ5 |
YFR041C |
Type I membrane protein with a J domain |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
BMT6 |
YLR063W |
Methyltransferase required for m3U2843 methylation of the 25S rRNA |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
AIM9 |
YER080W |
Protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
FAT3 |
YKL187C |
Protein required for fatty acid uptake |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ECM8 |
YBR076W |
Non-essential protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ECM23 |
YPL021W |
Non-essential protein of unconfirmed function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |