| RIM11 |
YMR139W |
Protein kinase |
genetic |
9 |
4 |
8 |
Dosage Rescue, Phenotypic Enhancement, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Dosage Rescue, Negative Genetic, Synthetic Growth Defect, Negative Genetic |
| RAD27 |
YKL113C |
5' to 3' exonuclease, 5' flap endonuclease |
genetic |
6 |
2 |
6 |
Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic |
| SCS7 |
YMR272C |
Sphingolipid alpha-hydroxylase |
genetic |
6 |
2 |
6 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic |
| COG6 |
YNL041C |
Component of the conserved oligomeric Golgi complex |
genetic |
6 |
2 |
6 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic |
| YPT6 |
YLR262C |
Rab family GTPase |
genetic |
6 |
1 |
6 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| BRE5 |
YNR051C |
Ubiquitin protease cofactor |
genetic |
6 |
1 |
6 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| ARO1 |
YDR127W |
Pentafunctional arom protein |
genetic |
5 |
2 |
5 |
Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic |
| CLB5 |
YPR120C |
B-type cyclin involved in DNA replication during S phase |
genetic |
5 |
2 |
5 |
Synthetic Lethality, Negative Genetic, Synthetic Lethality, Negative Genetic, Negative Genetic |
| INO4 |
YOL108C |
Transcription factor involved in phospholipid synthesis |
genetic |
5 |
1 |
5 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| SNF4 |
YGL115W |
Activating gamma subunit of the AMP-activated Snf1p kinase complex |
genetic |
5 |
1 |
5 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| DUN1 |
YDL101C |
Cell-cycle checkpoint S/T protein kinase |
genetic |
5 |
3 |
3 |
Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Phenotypic Suppression, Phenotypic Suppression |
| BIM1 |
YER016W |
Microtubule plus end-tracking protein |
genetic |
4 |
3 |
4 |
Synthetic Lethality, Synthetic Growth Defect, Negative Genetic, Synthetic Lethality |
| BRE2 |
YLR015W |
Subunit of COMPASS (Set1C) complex |
genetic |
4 |
2 |
4 |
Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic |
| SUB1 |
YMR039C |
Transcriptional regulator |
genetic |
4 |
2 |
4 |
Dosage Rescue, Negative Genetic, Negative Genetic, Negative Genetic |
| AIM22 |
YJL046W |
Lipoate-protein ligase |
genetic |
4 |
2 |
4 |
Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic |
| COG8 |
YML071C |
Component of the conserved oligomeric Golgi complex |
genetic |
4 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| SNT1 |
YCR033W |
Set3C histone deacetylase scaffold |
genetic |
4 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| SAC1 |
YKL212W |
Phosphatidylinositol phosphate phosphatase |
genetic |
4 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| RUD3 |
YOR216C |
Golgi matrix protein |
genetic |
4 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| IRS4 |
YKR019C |
EH domain-containing protein |
genetic |
4 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| CDC13 |
YDL220C |
Single stranded DNA-binding protein found at TG1-3 telomere G-tails |
genetic |
4 |
4 |
3 |
Synthetic Rescue, Phenotypic Enhancement, Phenotypic Suppression, Positive Genetic |
| ORC6 |
YHR118C |
Subunit of the origin recognition complex (ORC) |
genetic |
4 |
2 |
3 |
Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Positive Genetic |
| CDC6 |
YJL194W |
Essential ATP-binding protein required for DNA replication |
physical |
4 |
3 |
2 |
Two-hybrid, Affinity Capture-Western, Biochemical Activity, Biochemical Activity |
| RIM15 |
YFL033C |
Protein kinase involved in cell proliferation in response to nutrients |
genetic |
4 |
2 |
2 |
Phenotypic Enhancement, Synthetic Growth Defect, Phenotypic Enhancement, Synthetic Growth Defect |
| LSM1 |
YJL124C |
Lsm (Like Sm) protein |
genetic |
3 |
2 |
3 |
Positive Genetic, Negative Genetic, Negative Genetic |
| MMS22 |
YLR320W |
Subunit of E3 ubiquitin ligase complex involved in replication repair |
genetic |
3 |
2 |
3 |
Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect |
| SIC1 |
YLR079W |
Cyclin-dependent kinase inhibitor (CKI) |
genetic |
3 |
2 |
3 |
Negative Genetic, Negative Genetic, Synthetic Growth Defect |
| UBC4 |
YBR082C |
Ubiquitin-conjugating enzyme (E2) |
genetic |
3 |
2 |
3 |
Negative Genetic, Negative Genetic, Synthetic Growth Defect |
| COX5A |
YNL052W |
Subunit Va of cytochrome c oxidase |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| AEP2 |
YMR282C |
Mitochondrial protein |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| HTA1 |
YDR225W |
Histone H2A |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| HOM3 |
YER052C |
Aspartate kinase (L-aspartate 4-P-transferase) |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| CIK1 |
YMR198W |
Kinesin-associated protein |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| UME6 |
YDR207C |
Rpd3L histone deacetylase complex subunit |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| RIC1 |
YLR039C |
Protein involved in retrograde transport to the cis-Golgi network |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| SEC28 |
YIL076W |
Epsilon-COP subunit of the coatomer |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| SNF1 |
YDR477W |
AMP-activated S/T protein kinase |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| SRC1 |
YML034W |
Inner nuclear membrane protein |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| RPN10 |
YHR200W |
Proteasome polyubiquitin receptor |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| MMR1 |
YLR190W |
Phosphorylated protein of the mitochondrial outer membrane |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| SEO1 |
YAL067C |
Putative permease |
genetic |
3 |
1 |
3 |
Positive Genetic, Positive Genetic, Positive Genetic |
| QRI7 |
YDL104C |
Protein involved in threonylcarbamoyl adenosine biosynthesis |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| RPP1A |
YDL081C |
Ribosomal stalk protein P1 alpha |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| OMS1 |
YDR316W |
Protein integral to the mitochondrial membrane |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| SDC1 |
YDR469W |
Subunit of the COMPASS (Set1C) complex |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| MTO1 |
YGL236C |
Mitochondrial protein |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| YGL235W |
YGL235W |
Putative protein of unknown function |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| PEX31 |
YGR004W |
Peroxisomal integral membrane protein |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| ORM1 |
YGR038W |
Protein that mediates sphingolipid homeostasis |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| PTH1 |
YHR189W |
One of two mitochondrially-localized peptidyl-tRNA hydrolases |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| PBS2 |
YJL128C |
MAP kinase kinase of the HOG signaling pathway |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| RMA1 |
YKL132C |
Putative dihydrofolate synthetase |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| YKL107W |
YKL107W |
NADH-dependent aldehyde reductase |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| UPS2 |
YLR168C |
Mitochondrial intermembrane space protein |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| MSS1 |
YMR023C |
Mitochondrial protein |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| MRE11 |
YMR224C |
Nuclease subunit of the MRX complex with Rad50p and Xrs2p |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| TYE7 |
YOR344C |
Serine-rich protein that contains a bHLH DNA binding motif |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| TKL1 |
YPR074C |
Transketolase |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| HOM2 |
YDR158W |
Aspartic beta semi-aldehyde dehydrogenase |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| INO2 |
YDR123C |
Transcription factor |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| HAP4 |
YKL109W |
Transcription factor |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| ATP10 |
YLR393W |
Assembly factor for the F0 sector of mitochondrial F1F0 ATP synthase |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| HSV2 |
YGR223C |
Phosphatidylinositol 3,5-bisphosphate-binding protein |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| HBT1 |
YDL223C |
Shmoo tip protein, substrate of Hub1p ubiquitin-like protein |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| IXR1 |
YKL032C |
Transcriptional repressor that regulates hypoxic genes during normoxia |
genetic |
3 |
1 |
3 |
Positive Genetic, Positive Genetic, Positive Genetic |
| GVP36 |
YIL041W |
BAR domain protein that localizes to early and late Golgi vesicles |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| GCS1 |
YDL226C |
ADP-ribosylation factor GTPase activating protein (ARF GAP) |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| DEG1 |
YFL001W |
tRNA:pseudouridine synthase |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| AIM34 |
YMR003W |
Protein of unknown function |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| COX23 |
YHR116W |
Protein that functions in mitochondrial copper homeostasis |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| ARO7 |
YPR060C |
Chorismate mutase |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| HAL9 |
YOL089C |
Putative transcription factor containing a zinc finger |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| DSD1 |
YGL196W |
D-serine dehydratase (aka D-serine ammonia-lyase) |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| HMI1 |
YOL095C |
Mitochondrial inner membrane localized ATP-dependent DNA helicase |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| ATP23 |
YNR020C |
Putative metalloprotease of the mitochondrial inner membrane |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| ICE2 |
YIL090W |
Integral ER membrane protein with type-III transmembrane domains |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| RVB2 |
YPL235W |
ATP-dependent DNA helicase, also known as reptin |
genetic |
3 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect |
| PIH1 |
YHR034C |
Component of the conserved R2TP complex (Rvb1-Rvb2-Tah1-Pih1) |
genetic |
3 |
2 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect, Dosage Growth Defect |
| CTF18 |
YMR078C |
Subunit of a complex with Ctf8p |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
| GCN1 |
YGL195W |
Positive regulator of the Gcn2p kinase activity |
genetic |
2 |
2 |
2 |
Positive Genetic, Synthetic Growth Defect |
| HTZ1 |
YOL012C |
Histone variant H2AZ |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
| HSP82 |
YPL240C |
Hsp90 chaperone |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
| KNS1 |
YLL019C |
Protein kinase involved in negative regulation of PolIII transcription |
genetic |
2 |
2 |
2 |
Phenotypic Enhancement, Synthetic Growth Defect |
| ELM1 |
YKL048C |
Serine/threonine protein kinase |
genetic |
2 |
2 |
2 |
Dosage Growth Defect, Synthetic Growth Defect |
| CLB2 |
YPR119W |
B-type cyclin involved in cell cycle progression |
genetic |
2 |
2 |
2 |
Dosage Lethality, Synthetic Growth Defect |
| RGA2 |
YDR379W |
GTPase-activating protein for polarity-establishment protein Cdc42p |
physical |
2 |
2 |
2 |
Affinity Capture-MS, Biochemical Activity |
| YBR225W |
YBR225W |
Putative protein of unknown function |
physical |
2 |
2 |
2 |
Biochemical Activity, Affinity Capture-MS |
| SSD1 |
YDR293C |
Translational repressor |
physical |
2 |
2 |
2 |
Biochemical Activity, Affinity Capture-RNA |
| MIH1 |
YMR036C |
Protein tyrosine phosphatase |
physical |
2 |
2 |
2 |
Biochemical Activity, Affinity Capture-Western |
| MIH1 |
YMR036C |
Protein tyrosine phosphatase |
genetic |
2 |
2 |
2 |
Dosage Lethality, Dosage Growth Defect |
| POL3 |
YDL102W |
Catalytic subunit of DNA polymerase delta |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Negative Genetic |
| VID22 |
YLR373C |
G-quadruplex (G4) DNA binding protein |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
| RPA34 |
YJL148W |
RNA polymerase I subunit A34.5 |
genetic |
2 |
2 |
2 |
Positive Genetic, Synthetic Growth Defect |
| PKH1 |
YDR490C |
Serine/threonine protein kinase |
genetic |
2 |
2 |
2 |
Positive Genetic, Synthetic Growth Defect |
| RPN4 |
YDL020C |
Transcription factor that stimulates expression of proteasome genes |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Dosage Growth Defect |
| CTF8 |
YHR191C |
Subunit of a complex with Ctf18p |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
| ELO3 |
YLR372W |
Elongase |
genetic |
2 |
2 |
2 |
Synthetic Rescue, Synthetic Growth Defect |
| CBF2 |
YGR140W |
Essential kinetochore protein |
physical |
2 |
2 |
2 |
Two-hybrid, Biochemical Activity |
| ILM1 |
YJR118C |
Protein of unknown function |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Positive Genetic |
| BRE1 |
YDL074C |
E3 ubiquitin ligase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| HAP5 |
YOR358W |
Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ASF1 |
YJL115W |
Nucleosome assembly factor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| GIM3 |
YNL153C |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| HSP82 |
YPL240C |
Hsp90 chaperone |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| IRA2 |
YOL081W |
GTPase-activating protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| GET2 |
YER083C |
Subunit of the GET complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CTF4 |
YPR135W |
Chromatin-associated protein |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
| PTC1 |
YDL006W |
Type 2C protein phosphatase (PP2C) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PEX11 |
YOL147C |
Peroxisomal protein required for medium-chain fatty acid oxidation |
physical |
2 |
1 |
2 |
PCA, PCA |
| RAD53 |
YPL153C |
DNA damage response kinase |
genetic |
2 |
1 |
2 |
Dosage Rescue, Dosage Rescue |
| MEC1 |
YBR136W |
Genome integrity checkpoint protein and PI kinase superfamily member |
genetic |
2 |
1 |
2 |
Dosage Rescue, Dosage Rescue |
| UBP3 |
YER151C |
Ubiquitin-specific protease that cleaves Ub-protein fusions |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| MED8 |
YBR193C |
Subunit of the RNA polymerase II mediator complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| MSC1 |
YML128C |
Protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| MNN10 |
YDR245W |
Subunit of a Golgi mannosyltransferase complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| NUP84 |
YDL116W |
Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| VPS72 |
YDR485C |
Htz1p-binding component of the SWR1 complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| MIP1 |
YOR330C |
Mitochondrial DNA polymerase gamma |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ORM2 |
YLR350W |
Protein that mediates sphingolipid homeostasis |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SWI4 |
YER111C |
DNA binding component of the SBF complex (Swi4p-Swi6p) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RTS1 |
YOR014W |
B-type regulatory subunit of protein phosphatase 2A (PP2A) |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| SWD3 |
YBR175W |
Essential subunit of the COMPASS (Set1C) complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SDH4 |
YDR178W |
Membrane anchor subunit of succinate dehydrogenase (SDH) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RTT103 |
YDR289C |
Protein involved in transcription termination by RNA polymerase II |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PET122 |
YER153C |
Mitochondrial translational activator specific for the COX3 mRNA |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| VSB1 |
YGR125W |
Vacuolar membrane protein required for uptake and storage of arginine |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| OPI1 |
YHL020C |
Transcriptional regulator of a variety of genes |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| MED1 |
YPR070W |
Subunit of the RNA polymerase II mediator complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| QCR2 |
YPR191W |
Subunit 2 of ubiquinol cytochrome-c reductase (Complex III) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SWE1 |
YJL187C |
Protein kinase that regulates the G2/M transition |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
| SEC63 |
YOR254C |
Essential subunit of Sec63 complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| GIM4 |
YEL003W |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| HCM1 |
YCR065W |
Forkhead transcription factor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ERG2 |
YMR202W |
C-8 sterol isomerase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| KRE28 |
YDR532C |
Subunit of a kinetochore-microtubule binding complex |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| ISC1 |
YER019W |
Inositol phosphosphingolipid phospholipase C |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| EMI1 |
YDR512C |
Non-essential protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| FSH1 |
YHR049W |
Lysophospholipase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| LST4 |
YKL176C |
Subunit of the Lst4p-Lst7p GTPase activating protein complex for Gtr2p |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
genetic |
2 |
2 |
1 |
Positive Genetic, Negative Genetic |
| CDC14 |
YFR028C |
Protein phosphatase required for mitotic exit |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
| GPA2 |
YER020W |
Nucleotide binding alpha subunit of the heterotrimeric G protein |
physical |
2 |
2 |
1 |
Affinity Capture-Western, Biochemical Activity |
| MDS3 |
YGL197W |
Putative component of the TOR regulatory pathway |
genetic |
2 |
2 |
1 |
Synthetic Rescue, Dosage Rescue |
| RAD53 |
YPL153C |
DNA damage response kinase |
physical |
2 |
2 |
1 |
Two-hybrid, Biochemical Activity |
| SGV1 |
YPR161C |
Cyclin (Bur2p)-dependent protein kinase |
genetic |
2 |
2 |
1 |
Positive Genetic, Negative Genetic |
| YAK1 |
YJL141C |
Serine-threonine protein kinase |
genetic |
2 |
2 |
1 |
Phenotypic Enhancement, Synthetic Growth Defect |
| RFX1 |
YLR176C |
Major transcriptional repressor of DNA-damage-regulated genes |
genetic |
2 |
2 |
1 |
Synthetic Rescue, Phenotypic Enhancement |
| CDC19 |
YAL038W |
Pyruvate kinase |
physical |
2 |
2 |
1 |
Two-hybrid, Biochemical Activity |
| RPD3 |
YNL330C |
Histone deacetylase, component of both the Rpd3S and Rpd3L complexes |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
| FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| YAP6 |
YDR259C |
Basic leucine zipper (bZIP) transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| ABF1 |
YKL112W |
DNA binding protein with possible chromatin-reorganizing activity |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| CDC73 |
YLR418C |
Component of the Paf1p complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CWC2 |
YDL209C |
Member of the NineTeen Complex (NTC) |
physical |
1 |
1 |
1 |
Biochemical Activity |
| GWT1 |
YJL091C |
Protein involved in the inositol acylation of GlcN-PI |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LEO1 |
YOR123C |
Component of the Paf1 complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| CBF5 |
YLR175W |
Pseudouridine synthase catalytic subunit of box H/ACA snoRNPs |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| CKA2 |
YOR061W |
Alpha' catalytic subunit of casein kinase 2 (CK2) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CKB1 |
YGL019W |
Beta regulatory subunit of casein kinase 2 (CK2) |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| CKB1 |
YGL019W |
Beta regulatory subunit of casein kinase 2 (CK2) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| GLC7 |
YER133W |
Type 1 S/T protein phosphatase (PP1) catalytic subunit |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| FRT2 |
YAL028W |
Tail-anchored ER membrane protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
| GUS1 |
YGL245W |
Glutamyl-tRNA synthetase (GluRS) |
physical |
1 |
1 |
1 |
Biochemical Activity |
| BMH1 |
YER177W |
14-3-3 protein, major isoform |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IML1 |
YJR138W |
GTPase-activating protein (GAP) subunit of the Iml1p/SEACIT complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| GCD1 |
YOR260W |
Gamma subunit of the translation initiation factor eIF2B |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AAR2 |
YBL074C |
Component of the U5 snRNP complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ALA1 |
YOR335C |
Cytoplasmic and mitochondrial alanyl-tRNA synthetase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| BCP1 |
YDR361C |
Essential nuclear chaperone for ribosomal protein Rpl23p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| APL3 |
YBL037W |
Alpha-adaptin |
physical |
1 |
1 |
1 |
Biochemical Activity |
| BET3 |
YKR068C |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CAP1 |
YKL007W |
Alpha subunit of the capping protein heterodimer (Cap1p and Cap2p) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| CDC28 |
YBR160W |
Cyclin-dependent kinase (CDK) catalytic subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC11 |
YJR076C |
Component of the septin ring that is required for cytokinesis |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| CDC12 |
YHR107C |
Component of the septin ring that is required for cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DCP2 |
YNL118C |
Catalytic subunit of Dcp1p-Dcp2p decapping enzyme complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DNA2 |
YHR164C |
ATP-dependent 5'-flap endonuclease and DNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC16 |
YKL022C |
Subunit of the anaphase-promoting complex/cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC23 |
YHR166C |
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EAF3 |
YPR023C |
Component of the Rpd3S histone deacetylase complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| ERG13 |
YML126C |
3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ERP2 |
YAL007C |
Member of the p24 family involved in ER to Golgi transport |
physical |
1 |
1 |
1 |
Biochemical Activity |
| FKS1 |
YLR342W |
Catalytic subunit of 1,3-beta-D-glucan synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| FKS1 |
YLR342W |
Catalytic subunit of 1,3-beta-D-glucan synthase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| GCD7 |
YLR291C |
Beta subunit of translation initiation factor eIF2B |
physical |
1 |
1 |
1 |
Two-hybrid |
| GCD7 |
YLR291C |
Beta subunit of translation initiation factor eIF2B |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GLO3 |
YER122C |
ADP-ribosylation factor GTPase activating protein (ARF GAP) |
physical |
1 |
1 |
1 |
Biochemical Activity |
| ERV25 |
YML012W |
Member of the p24 family involved in ER to Golgi transport |
physical |
1 |
1 |
1 |
Biochemical Activity |
| ESP1 |
YGR098C |
Separase/separin, a caspase-like cysteine protease |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| BDF2 |
YDL070W |
Protein involved in transcription initiation |
physical |
1 |
1 |
1 |
Biochemical Activity |
| DYN1 |
YKR054C |
Cytoplasmic heavy chain dynein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| HSL1 |
YKL101W |
Nim1p-related protein kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| HSL1 |
YKL101W |
Nim1p-related protein kinase |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| FAP7 |
YDL166C |
Essential NTPase required for small ribosome subunit synthesis |
physical |
1 |
1 |
1 |
Biochemical Activity |
| LCB2 |
YDR062W |
Component of serine palmitoyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HSC82 |
YMR186W |
Cytoplasmic chaperone of the Hsp90 family |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HSC82 |
YMR186W |
Cytoplasmic chaperone of the Hsp90 family |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| GEP3 |
YOR205C |
Protein required for mitochondrial ribosome small subunit biogenesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CMR1 |
YDL156W |
Nuclear protein with role in transcription, protein quality control |
physical |
1 |
1 |
1 |
Biochemical Activity |
| ATG3 |
YNR007C |
E2-like enzyme |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| CMD1 |
YBR109C |
Calmodulin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARP8 |
YOR141C |
Nuclear actin-related protein involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GCN20 |
YFR009W |
Positive regulator of the Gcn2p kinase activity |
physical |
1 |
1 |
1 |
Biochemical Activity |
| CTI6 |
YPL181W |
Component of the Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| CDC6 |
YJL194W |
Essential ATP-binding protein required for DNA replication |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CDC25 |
YLR310C |
Membrane bound guanine nucleotide exchange factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HFI1 |
YPL254W |
Adaptor protein required for structural integrity of the SAGA complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IST2 |
YBR086C |
Cortical ER protein involved in ER-plasma membrane (PM) tethering |
physical |
1 |
1 |
1 |
Biochemical Activity |
| CCT6 |
YDR188W |
Subunit of the cytosolic chaperonin Cct ring complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATG9 |
YDL149W |
Transmembrane protein involved in forming Cvt and autophagic vesicles |
physical |
1 |
1 |
1 |
Biochemical Activity |
| BET5 |
YML077W |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ACE2 |
YLR131C |
Transcription factor required for septum destruction after cytokinesis |
physical |
1 |
1 |
1 |
Biochemical Activity |
| HSE1 |
YHL002W |
Subunit of the endosomal Vps27p-Hse1p complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| FUN19 |
YAL034C |
Non-essential protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
| EDC3 |
YEL015W |
Non-essential conserved protein with a role in mRNA decapping |
physical |
1 |
1 |
1 |
Biochemical Activity |
| GPH1 |
YPR160W |
Glycogen phosphorylase required for the mobilization of glycogen |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| CRZ1 |
YNL027W |
Transcription factor, activates transcription of stress response genes |
physical |
1 |
1 |
1 |
Biochemical Activity |
| CRZ1 |
YNL027W |
Transcription factor, activates transcription of stress response genes |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| ACO1 |
YLR304C |
Aconitase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| BBC1 |
YJL020C |
Protein possibly involved in assembly of actin patches |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| CSR2 |
YPR030W |
Nuclear ubiquitin protein ligase binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CAF20 |
YOR276W |
Phosphoprotein of the mRNA cap-binding complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ARF1 |
YDL192W |
ADP-ribosylation factor |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| CHK1 |
YBR274W |
Serine/threonine kinase and DNA damage checkpoint effector |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| CAF120 |
YNL278W |
Part of the CCR4-NOT transcriptional regulatory complex |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| CMK1 |
YFR014C |
Calmodulin-dependent protein kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| FAR1 |
YJL157C |
CDK inhibitor and nuclear anchor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HSP104 |
YLL026W |
Disaggregase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| KRE6 |
YPR159W |
Glucosyl hydrolase required for beta-1,6-glucan biosynthesis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| BUL1 |
YMR275C |
Alpha-arrestin, component of the Rsp5p E3-ubiquitin ligase complex |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| ADH4 |
YGL256W |
Alcohol dehydrogenase isoenzyme type IV |
physical |
1 |
1 |
1 |
Biochemical Activity |
| IPA1 |
YJR141W |
Protein implicated in pre-mRNA processing and proteasomal degradation |
physical |
1 |
1 |
1 |
Biochemical Activity |
| CDC37 |
YDR168W |
Essential Hsp90p co-chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC4 |
YFL009W |
F-box protein required for both the G1/S and G2/M phase transitions |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CIN8 |
YEL061C |
Bipolar kinesin motor protein |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| CDC15 |
YAR019C |
Hippo-like kinase of the Mitotic Exit Network |
physical |
1 |
1 |
1 |
Biochemical Activity |
| KRI1 |
YNL308C |
Essential nucleolar protein required for 40S ribosome biogenesis |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| CAC2 |
YML102W |
Subunit of chromatin assembly factor I (CAF-1), with Rlf2p and Msi1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DIA2 |
YOR080W |
Origin-binding F-box protein |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| DPB11 |
YJL090C |
DNA replication initiation protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HAL5 |
YJL165C |
Snf1p-related nutrient-responsive protein kinase |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| FPK1 |
YNR047W |
Ser/Thr protein kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| CLB2 |
YPR119W |
B-type cyclin involved in cell cycle progression |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| TRM3 |
YDL112W |
2'-O-ribose methyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SLM1 |
YIL105C |
Phosphoinositide PI4,5P(2) binding protein, forms a complex with Slm2p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SLM1 |
YIL105C |
Phosphoinositide PI4,5P(2) binding protein, forms a complex with Slm2p |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| PNT1 |
YOR266W |
Mitochondrial integral inner membrane protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| UME6 |
YDR207C |
Rpd3L histone deacetylase complex subunit |
physical |
1 |
1 |
1 |
Two-hybrid |
| MCK1 |
YNL307C |
Dual-specificity ser/thr and tyrosine protein kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| PRD1 |
YCL057W |
Zinc metalloendopeptidase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MCY1 |
YGR012W |
Putative cysteine synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SNF2 |
YOR290C |
Catalytic subunit of the SWI/SNF chromatin remodeling complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RGP1 |
YDR137W |
Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RGP1 |
YDR137W |
Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RSC1 |
YGR056W |
Component of the RSC chromatin remodeling complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MCM2 |
YBL023C |
Protein involved in DNA replication |
physical |
1 |
1 |
1 |
Biochemical Activity |
| POL32 |
YJR043C |
Third subunit of DNA polymerase delta |
physical |
1 |
1 |
1 |
Biochemical Activity |
| ROG3 |
YFR022W |
Alpha-arrestin involved in ubiquitin-dependent endocytosis |
physical |
1 |
1 |
1 |
Biochemical Activity |
| ROG3 |
YFR022W |
Alpha-arrestin involved in ubiquitin-dependent endocytosis |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| STB2 |
YMR053C |
Protein that interacts with Sin3p in a two-hybrid assay |
physical |
1 |
1 |
1 |
Biochemical Activity |
| RNT1 |
YMR239C |
Nuclear dsRNA-specific ribonuclease (RNase III) |
physical |
1 |
1 |
1 |
Biochemical Activity |
| SSK1 |
YLR006C |
Cytoplasmic phosphorelay intermediate osmosensor and regulator |
physical |
1 |
1 |
1 |
Biochemical Activity |
| PSY2 |
YNL201C |
Subunit of protein phosphatase PP4 complex |
physical |
1 |
1 |
1 |
Biochemical Activity |
| SOL2 |
YCR073W-A |
Protein with a possible role in tRNA export |
physical |
1 |
1 |
1 |
Biochemical Activity |
| TRM13 |
YOL125W |
2'-O-methyltransferase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| RRP5 |
YMR229C |
RNA binding protein involved in synthesis of 18S and 5.8S rRNAs |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YDL186W |
YDL186W |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
| NHP10 |
YDL002C |
Non-essential INO80 chromatin remodeling complex subunit |
physical |
1 |
1 |
1 |
Biochemical Activity |
| NHP10 |
YDL002C |
Non-essential INO80 chromatin remodeling complex subunit |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| YML045W-A |
YML045W-A |
Retrotransposon TYA Gag gene co-transcribed with TYB Pol |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YAP6 |
YDR259C |
Basic leucine zipper (bZIP) transcription factor |
physical |
1 |
1 |
1 |
Biochemical Activity |
| SES1 |
YDR023W |
Cytosolic seryl-tRNA synthetase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| PTC1 |
YDL006W |
Type 2C protein phosphatase (PP2C) |
physical |
1 |
1 |
1 |
Biochemical Activity |
| RIX7 |
YLL034C |
Putative ATPase of the AAA family |
physical |
1 |
1 |
1 |
Biochemical Activity |
| PFK2 |
YMR205C |
Beta subunit of heterooctameric phosphofructokinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| PPN2 |
YNL217W |
Zn2+-dependent endopolyphosphatase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YPL077C |
YPL077C |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
| PAH1 |
YMR165C |
Mg2+-dependent phosphatidate (PA) phosphatase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| PAH1 |
YMR165C |
Mg2+-dependent phosphatidate (PA) phosphatase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| UBX7 |
YBR273C |
UBX (ubiquitin regulatory X) domain-containing protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
| RET1 |
YOR207C |
Second-largest subunit of RNA polymerase III |
physical |
1 |
1 |
1 |
Biochemical Activity |
| RET1 |
YOR207C |
Second-largest subunit of RNA polymerase III |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YRB1 |
YDR002W |
Ran GTPase binding protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YMC1 |
YPR058W |
Secondary mitochondrial inner membrane glycine transporter |
physical |
1 |
1 |
1 |
Biochemical Activity |
| VPS27 |
YNR006W |
Endosomal protein that forms a complex with Hse1p |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YNL284C-A |
YNL284C-A |
Retrotransposon TYA Gag gene co-transcribed with TYB Pol |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YGR038C-A |
YGR038C-A |
Retrotransposon TYA Gag gene co-transcribed with TYB Pol |
physical |
1 |
1 |
1 |
Biochemical Activity |
| SEC2 |
YNL272C |
Guanyl-nucleotide exchange factor for the small G-protein Sec4p |
physical |
1 |
1 |
1 |
Biochemical Activity |
| USB1 |
YLR132C |
Putative poly(U)-specific 3'-to-5' RNA exonuclease |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YLR030W |
YLR030W |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
| SPO21 |
YOL091W |
Component of the meiotic outer plaque of the spindle pole body |
physical |
1 |
1 |
1 |
Biochemical Activity |
| VHS2 |
YIL135C |
Regulator of septin dynamics |
physical |
1 |
1 |
1 |
Biochemical Activity |
| NCL1 |
YBL024W |
S-adenosyl-L-methionine-dependent tRNA: m5C-methyltransferase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| SAS10 |
YDL153C |
Subunit of U3-containing Small Subunit (SSU) processome complex |
physical |
1 |
1 |
1 |
Biochemical Activity |
| MGR3 |
YMR115W |
Subunit of the mitochondrial (mt) i-AAA protease supercomplex |
physical |
1 |
1 |
1 |
Biochemical Activity |
| MGR3 |
YMR115W |
Subunit of the mitochondrial (mt) i-AAA protease supercomplex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRPL9 |
YGR220C |
Mitochondrial ribosomal protein of the large subunit |
physical |
1 |
1 |
1 |
Biochemical Activity |
| UBP9 |
YER098W |
Ubiquitin-specific protease that cleaves ubiquitin-protein fusions |
physical |
1 |
1 |
1 |
Biochemical Activity |
| UBX5 |
YDR330W |
UBX domain-containing protein that interacts with Cdc48p |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YEF3 |
YLR249W |
Translation elongation factor 3 |
physical |
1 |
1 |
1 |
Biochemical Activity |
| SML1 |
YML058W |
Ribonucleotide reductase inhibitor |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YML037C |
YML037C |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
| VCX1 |
YDL128W |
Vacuolar membrane antiporter with Ca2+/H+ and K+/H+ exchange activity |
physical |
1 |
1 |
1 |
Biochemical Activity |
| SUN4 |
YNL066W |
Cell wall protein related to glucanases localized in birth scars |
physical |
1 |
1 |
1 |
Biochemical Activity |
| PRM10 |
YJL108C |
Pheromone-regulated protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
| MLF3 |
YNL074C |
Serine-rich protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
| PCL10 |
YGL134W |
Pho85p cyclin |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YGR126W |
YGR126W |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
| QDR3 |
YBR043C |
Multidrug transporter of the major facilitator superfamily |
physical |
1 |
1 |
1 |
Biochemical Activity |
| PTP1 |
YDL230W |
Phosphotyrosine-specific protein phosphatase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| MTW1 |
YAL034W-A |
Essential component of the MIND kinetochore complex |
physical |
1 |
1 |
1 |
Biochemical Activity |
| SCT1 |
YBL011W |
Glycerol 3-phosphate/dihydroxyacetone phosphate sn-1 acyltransferase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YPL257W-A |
YPL257W-A |
Retrotransposon TYA Gag gene co-transcribed with TYB Pol |
physical |
1 |
1 |
1 |
Biochemical Activity |
| RPB8 |
YOR224C |
RNA polymerase subunit ABC14.5 |
physical |
1 |
1 |
1 |
Biochemical Activity |
| NIS1 |
YNL078W |
Protein involved in axial bud site selection |
physical |
1 |
1 |
1 |
Biochemical Activity |
| MST27 |
YGL051W |
Putative integral membrane protein, involved in vesicle formation |
physical |
1 |
1 |
1 |
Biochemical Activity |
| RNH70 |
YGR276C |
3'-5' exoribonuclease |
physical |
1 |
1 |
1 |
Biochemical Activity |
| TPN1 |
YGL186C |
Plasma membrane pyridoxine (vitamin B6) transporter |
physical |
1 |
1 |
1 |
Biochemical Activity |
| SWT21 |
YNL187W |
Protein involved in mRNA splicing |
physical |
1 |
1 |
1 |
Biochemical Activity |
| MYO5 |
YMR109W |
One of two type I myosin motors |
physical |
1 |
1 |
1 |
Two-hybrid |
| UBR1 |
YGR184C |
E3 ubiquitin ligase (N-recognin) |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| MDS3 |
YGL197W |
Putative component of the TOR regulatory pathway |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MNR2 |
YKL064W |
Vacuolar membrane protein required for magnesium homeostasis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MTC5 |
YDR128W |
Subunit of SEACAT, a subcomplex of the SEA complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NET1 |
YJL076W |
Core subunit of the RENT complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NOP15 |
YNL110C |
Constituent of 66S pre-ribosomal particles |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NPR2 |
YEL062W |
Subunit of the Iml1p/SEACIT complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PMD1 |
YER132C |
Protein with an N-terminal kelch-like domain |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PMD1 |
YER132C |
Protein with an N-terminal kelch-like domain |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| PRM5 |
YIL117C |
Pheromone-regulated protein, predicted to have 1 transmembrane segment |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PSH1 |
YOL054W |
E3 ubiquitin ligase targeting centromere-binding protein Cse4p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PSH1 |
YOL054W |
E3 ubiquitin ligase targeting centromere-binding protein Cse4p |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| NPR3 |
YHL023C |
Subunit of the Iml1p/SEACIT complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RTC1 |
YOL138C |
Subunit of SEACAT, a subcomplex of the SEA complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SEC13 |
YLR208W |
Structural component of 3 complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SEH1 |
YGL100W |
Subunit of the Nup84 nuclear pore and SEACAT subcomplexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| STE2 |
YFL026W |
Receptor for alpha-factor pheromone |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| URE2 |
YNL229C |
Nitrogen catabolite repression transcriptional regulator |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YBL100W-A |
YBL100W-A |
Retrotransposon TYA Gag gene co-transcribed with TYB Pol |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SEA4 |
YBL104C |
Subunit of SEACAT, a subcomplex of the SEA complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YER138C |
YER138C |
Retrotransposon TYA Gag and TYB Pol genes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YER160C |
YER160C |
Retrotransposon TYA Gag and TYB Pol genes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NNK1 |
YKL171W |
Protein kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YMR295C |
YMR295C |
Protein of unknown function that associates with ribosomes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YNL058C |
YNL058C |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RGC1 |
YPR115W |
Putative regulator of the Fps1p glycerol channel |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YPR089W |
YPR089W |
Protein of unknown function |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| RPC53 |
YDL150W |
RNA polymerase III subunit C53 |
physical |
1 |
1 |
1 |
Biochemical Activity |
| SBP1 |
YHL034C |
Protein that binds eIF4G and has a role in repression of translation |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| PUF3 |
YLL013C |
Protein of the mitochondrial outer surface |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| SSB2 |
YNL209W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
1 |
1 |
1 |
Co-purification |
| MLP1 |
YKR095W |
Myosin-like protein associated with the nuclear envelope |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MLP1 |
YKR095W |
Myosin-like protein associated with the nuclear envelope |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| MMS22 |
YLR320W |
Subunit of E3 ubiquitin ligase complex involved in replication repair |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PUF2 |
YPR042C |
PUF family mRNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| RVB1 |
YDR190C |
ATP-dependent DNA helicase, also known as pontin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MPT5 |
YGL178W |
mRNA-binding protein of the PUF family |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| SLD2 |
YKL108W |
Single-stranded DNA origin-binding and annealing protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
| TFC6 |
YDR362C |
Subunit of RNA polymerase III transcription initiation factor complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SBH1 |
YER087C-B |
Beta subunit of Sec61p ER translocation complex (Sec61p-Sss1p-Sbh1p) |
physical |
1 |
1 |
1 |
Two-hybrid |
| RPS2 |
YGL123W |
Protein component of the small (40S) subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS3 |
YNL178W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YVH1 |
YIR026C |
Dual specificity protein phosphatase |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| MSN2 |
YMR037C |
Stress-responsive transcriptional activator |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| RIM13 |
YMR154C |
Calpain-like cysteine protease |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| RIM8 |
YGL045W |
Protein involved in proteolytic activation of Rim101p |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| RIM9 |
YMR063W |
Plasma membrane protein of unknown function |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| RIM101 |
YHL027W |
Cys2His2 zinc-finger transcriptional repressor |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| MRK1 |
YDL079C |
Glycogen synthase kinase 3 (GSK-3) homolog |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| YGK3 |
YOL128C |
Protein kinase related to mammalian GSK-3 glycogen synthase kinases |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| ZDS1 |
YMR273C |
Protein with a role in regulating Swe1p-dependent polarized growth |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| ROG1 |
YGL144C |
Lipase with specificity for monoacylglycerol |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| MSS4 |
YDR208W |
Phosphatidylinositol-4-phosphate 5-kinase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| ZRT1 |
YGL255W |
High-affinity zinc transporter of the plasma membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SLX8 |
YER116C |
Subunit of Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TRS85 |
YDR108W |
Component of transport protein particle (TRAPP) complex III |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPC34 |
YNR003C |
RNA polymerase III subunit C34 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPF1 |
YEL031W |
P-type ATPase, ion transporter of the ER membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SHP1 |
YBL058W |
UBX domain-containing substrate adaptor for Cdc48p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| STB5 |
YHR178W |
Transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SLX5 |
YDL013W |
Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPB3 |
YIL021W |
RNA polymerase II third largest subunit B44 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SQS1 |
YNL224C |
Protein that stimulates the ATPase and helicase activities of Prp43p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RMI1 |
YPL024W |
Subunit of the RecQ (Sgs1p) - Topo III (Top3p) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RAD3 |
YER171W |
5' to 3' DNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| XRN1 |
YGL173C |
Evolutionarily-conserved 5'-3' exonuclease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NUT1 |
YGL151W |
Component of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TAF12 |
YDR145W |
Subunit (61/68 kDa) of TFIID and SAGA complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YAF9 |
YNL107W |
Subunit of NuA4 histone H4 acetyltransferase and SWR1 complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TFB2 |
YPL122C |
Subunit of TFIIH and nucleotide excision repair factor 3 complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TAF9 |
YMR236W |
Subunit (17 kDa) of TFIID and SAGA complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MET18 |
YIL128W |
Component of cytosolic iron-sulfur protein assembly (CIA) machinery |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWC5 |
YBR231C |
Component of the SWR1 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PAF1 |
YBR279W |
Component of the Paf1p complex involved in transcription elongation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| OPI3 |
YJR073C |
Methylene-fatty-acyl-phospholipid synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWC3 |
YAL011W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RAD52 |
YML032C |
Protein involved in homologous recombination |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TIM18 |
YOR297C |
Component of the mitochondrial TIM22 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PFD1 |
YJL179W |
Subunit of heterohexameric prefoldin |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SSN3 |
YPL042C |
Component of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPN13 |
YLR421C |
Subunit of the 19S regulatory particle of the 26S proteasome lid |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPC40 |
YPR110C |
RNA polymerase subunit AC40 |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YHP1 |
YDR451C |
Homeobox transcriptional repressor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RSC8 |
YFR037C |
Component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPA14 |
YDR156W |
RNA polymerase I subunit A14 |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PGM1 |
YKL127W |
Phosphoglucomutase, minor isoform |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| RTT109 |
YLL002W |
Histone acetyltransferase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| REG1 |
YDR028C |
Regulatory subunit of type 1 protein phosphatase Glc7p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SOH1 |
YGL127C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MNN11 |
YJL183W |
Subunit of a Golgi mannosyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PTK2 |
YJR059W |
Serine/threonine protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TRA1 |
YHR099W |
Subunit of SAGA and NuA4 histone acetyltransferase complexes |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| NIP100 |
YPL174C |
Large subunit of the dynactin complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| VMA21 |
YGR105W |
Integral membrane protein required for V-ATPase function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| VOA1 |
YGR106C |
ER protein that functions in assembly of the V0 sector of V-ATPase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| NAT5 |
YOR253W |
Subunit of protein N-terminal acetyltransferase NatA |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| NRD1 |
YNL251C |
RNA-binding subunit of Nrd1 complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| VPH2 |
YKL119C |
Integral membrane protein required for V-ATPase function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS1 |
YKR001C |
Dynamin-like GTPase required for vacuolar sorting |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TLG2 |
YOL018C |
Syntaxin-like t-SNARE |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MDM32 |
YOR147W |
Mitochondrial inner membrane protein with similarity to Mdm31p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YME1 |
YPR024W |
Catalytic subunit of i-AAA protease complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PAM16 |
YJL104W |
Subunit of the import motor (PAM complex) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| NPL3 |
YDR432W |
RNA-binding protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| YKU70 |
YMR284W |
Subunit of the telomeric Ku complex (Yku70p-Yku80p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PMP3 |
YDR276C |
Small plasma membrane protein |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| YRR1 |
YOR162C |
Zn2-Cys6 zinc-finger transcription factor |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| YMR181C |
YMR181C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| YAP3 |
YHL009C |
Basic leucine zipper (bZIP) transcription factor |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| ZAP1 |
YJL056C |
Zinc-regulated transcription factor |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| MIA40 |
YKL195W |
Import and assembly protein in mitochondrial intermembrane space |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| RRN6 |
YBL014C |
Component of the core factor (CF) rDNA transcription factor complex |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| YNL108C |
YNL108C |
Protein phosphatase |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| YIL089W |
YIL089W |
Protein of unknown function found in the ER and vacuole lumen |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| TSR2 |
YLR435W |
Protein with a potential role in pre-rRNA processing |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| YMR206W |
YMR206W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| OSH7 |
YHR001W |
Oxysterol-binding phosphatidylserine transferase |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| TOA2 |
YKL058W |
TFIIA small subunit |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| UGP1 |
YKL035W |
UDP-glucose pyrophosphorylase (UGPase) |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| MCM1 |
YMR043W |
Transcription factor |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| SLX4 |
YLR135W |
Endonuclease involved in processing DNA |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| THO1 |
YER063W |
Conserved nuclear RNA-binding protein |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| MKK1 |
YOR231W |
MAPKK involved in the protein kinase C signaling pathway |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| PRY1 |
YJL079C |
Lipid binding protein |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| PEX18 |
YHR160C |
Peroxin |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| YMR1 |
YJR110W |
Phosphatidylinositol 3-phosphate (PI3P) phosphatase |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| PPH3 |
YDR075W |
Catalytic subunit of protein phosphatase PP4 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS74 |
YDR372C |
Golgi PI4K effector, PtdIns4P sensor, and retention receptor |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| PUB1 |
YNL016W |
Poly (A)+ RNA-binding protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| RPL42A |
YNL162W |
Ribosomal 60S subunit protein L42A |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| MSH2 |
YOL090W |
Protein that binds to DNA mismatches |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| SWD1 |
YAR003W |
Subunit of the COMPASS (Set1C) complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| PHO5 |
YBR093C |
Repressible acid phosphatase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| RPS6B |
YBR181C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| RPS9B |
YBR189W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| RRT2 |
YBR246W |
Methylesterase performing penultimate step of diphthamide biosynthesis |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| SGF29 |
YCL010C |
Component of the HAT/Core module of the SAGA, SLIK, and ADA complexes |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| OCA4 |
YCR095C |
Cytoplasmic protein required for replication of Brome mosaic virus |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| OST4 |
YDL232W |
Subunit of the oligosaccharyltransferase complex of the ER lumen |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| VPS60 |
YDR486C |
Protein involved in late endosome to vacuole transport |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| MON1 |
YGL124C |
Subunit of a heterodimeric guanine nucleotide exchange factor (GEF) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| PRE9 |
YGR135W |
Alpha 3 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| SKN7 |
YHR206W |
Nuclear response regulator and transcription factor |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| RPE1 |
YJL121C |
D-ribulose-5-phosphate 3-epimerase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| STM1 |
YLR150W |
Protein required for optimal translation under nutrient stress |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| ROM2 |
YLR371W |
Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| RCO1 |
YMR075W |
Essential component of the Rpd3S histone deacetylase complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| YKU80 |
YMR106C |
Subunit of telomeric Ku complex (Yku70p-Yku80p) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| VAC7 |
YNL054W |
Integral vacuolar membrane protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| SLG1 |
YOR008C |
Sensor-transducer of the stress-activated PKC1-MPK1 kinase pathway |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| VPS17 |
YOR132W |
Subunit of the membrane-associated retromer complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| ULS1 |
YOR191W |
Swi2/Snf2-related translocase, SUMO-Targeted Ubiquitin Ligase (STUbL) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| RPS6A |
YPL090C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| ZTA1 |
YBR046C |
NADPH-dependent quinone reductase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| RPS25A |
YGR027C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| TMA22 |
YJR014W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| SPE1 |
YKL184W |
Ornithine decarboxylase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| SAL1 |
YNL083W |
ADP/ATP transporter |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| RHO3 |
YIL118W |
Non-essential small GTPase of the Rho/Rac family of Ras-like proteins |
genetic |
1 |
1 |
1 |
Positive Genetic |
| STE50 |
YCL032W |
Adaptor protein for various signaling pathways |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TEF4 |
YKL081W |
Gamma subunit of translational elongation factor eEF1B |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NUP188 |
YML103C |
Subunit of the inner ring of the nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RIM20 |
YOR275C |
Protein involved in proteolytic activation of Rim101p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| STU1 |
YBL034C |
Microtubule plus-end-tracking non-motor protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC17 |
YBL050W |
Alpha-SNAP cochaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PKC1 |
YBL105C |
Protein serine/threonine kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TRS20 |
YBR254C |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPN6 |
YDL097C |
Essential, non-ATPase regulatory subunit of the 26S proteasome lid |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPC11 |
YDR045C |
RNA polymerase III subunit C11 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PDC2 |
YDR081C |
Transcription factor for thiamine-regulated genes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SUP35 |
YDR172W |
Translation termination factor eRF3 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SLY1 |
YDR189W |
Hydrophilic protein involved in ER/Golgi vesicle trafficking |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC26 |
YDR238C |
Essential beta-coat protein of the COPI coatomer |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TRS23 |
YDR246W |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPC110 |
YDR356W |
Inner plaque spindle pole body (SPB) component |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPB7 |
YDR404C |
RNA polymerase II subunit B16 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SYF1 |
YDR416W |
Member of the NineTeen Complex (NTC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TSC11 |
YER093C |
Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RSP5 |
YER125W |
NEDD4 family E3 ubiquitin ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPN11 |
YFR004W |
Metalloprotease subunit of 19S regulatory particle |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NBP35 |
YGL091C |
Essential cytoplasmic iron-sulfur cluster binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC27 |
YGL137W |
Essential beta'-coat protein of the COPI coatomer |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRP18 |
YGR006W |
Splicing factor and component of snRNP U5 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SKI6 |
YGR195W |
Exosome non-catalytic core component |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SDA1 |
YGR245C |
Protein required for actin organization and passage through Start |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MED6 |
YHR058C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPF1 |
YHR088W |
Protein involved in assembly and export of the large ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MCM10 |
YIL150C |
Essential chromatin-associated protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| STS1 |
YIR011C |
Protein required for localizing proteasomes to the nucleus |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SSL1 |
YLR005W |
Subunit of the core form of RNA polymerase transcription factor TFIIH |
genetic |
1 |
1 |
1 |
Negative Genetic |
| STU2 |
YLR045C |
Microtubule polymerase of the XMAP215/Dis1 family |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC22 |
YLR268W |
R-SNARE protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC61 |
YLR378C |
Conserved ER protein translocation channel |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEN1 |
YLR430W |
ATP-dependent 5' to 3' RNA/DNA and DNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| POB3 |
YML069W |
Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VTI1 |
YMR197C |
Protein involved in cis-Golgi membrane traffic |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TAF7 |
YMR227C |
TFIID subunit (67 kDa) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SGT1 |
YOR057W |
Cochaperone protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MGE1 |
YOR232W |
Mitochondrial matrix cochaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SUA7 |
YPR086W |
Transcription factor TFIIB |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MIS1 |
YBR084W |
Mitochondrial C1-tetrahydrofolate synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RXT2 |
YBR095C |
Component of the histone deacetylase Rpd3L complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YSA1 |
YBR111C |
Nudix hydrolase family member with ADP-ribose pyrophosphatase activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PAT1 |
YCR077C |
Deadenylation-dependent mRNA-decapping factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SLM3 |
YDL033C |
tRNA-specific 2-thiouridylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRPL1 |
YDR116C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YDR248C |
YDR248C |
Putative gluconokinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YCK3 |
YER123W |
Palmitoylated vacuolar membrane-localized casein kinase I isoform |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MDM34 |
YGL219C |
Mitochondrial component of the ERMES complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UPF3 |
YGR072W |
Component of the nonsense-mediated mRNA decay (NMD) pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
| STP2 |
YHR006W |
Transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TED1 |
YIL039W |
GPI-glycan remodelase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS53 |
YJL029C |
Component of the GARP (Golgi-associated retrograde protein) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS51 |
YKR020W |
Component of the GARP (Golgi-associated retrograde protein) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MIX17 |
YMR002W |
Mitochondrial intermembrane space protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWS2 |
YNL081C |
Putative mitochondrial ribosomal protein of the small subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PHO23 |
YNL097C |
Component of the Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ULA1 |
YPL003W |
Protein that activates Rub1p (NEDD8) before neddylation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRX11 |
YPL041C |
Protein that associates with mitochondrial ribosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RAS2 |
YNL098C |
GTP-binding protein |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| PMA1 |
YGL008C |
Plasma membrane P2-type H+-ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TAT2 |
YOL020W |
High affinity tryptophan and tyrosine permease |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| TUB4 |
YLR212C |
Gamma-tubulin |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| FAL1 |
YDR021W |
Nucleolar protein required for maturation of 18S rRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FUS3 |
YBL016W |
Mitogen-activated serine/threonine protein kinase involved in mating |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GCR2 |
YNL199C |
Transcriptional activator of genes involved in glycolysis |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| CIN5 |
YOR028C |
Basic leucine zipper (bZIP) transcription factor of the yAP-1 family |
physical |
1 |
1 |
1 |
Biochemical Activity |
| BIR1 |
YJR089W |
Subunit of chromosomal passenger complex (CPC) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CDC7 |
YDL017W |
S/T kinase and catalytic subunit of DDK (Dbf4-dependent kinase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KKQ8 |
YKL168C |
Putative serine/threonine protein kinase with unknown cellular role |
physical |
1 |
1 |
1 |
Biochemical Activity |
| DAD1 |
YDR016C |
Essential subunit of the Dam1 complex (aka DASH complex) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HOF1 |
YMR032W |
F-BAR protein that regulates actin cytoskeleton organization |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARP1 |
YHR129C |
Actin-related protein of the dynactin complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| ALR1 |
YOL130W |
Plasma membrane Mg(2+) transporter |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| EBS1 |
YDR206W |
Protein involved in translation inhibition and nonsense-mediated decay |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| GZF3 |
YJL110C |
GATA zinc finger protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
| GZF3 |
YJL110C |
GATA zinc finger protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| LEU4 |
YNL104C |
Alpha-isopropylmalate synthase (2-isopropylmalate synthase) |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| MAD3 |
YJL013C |
Subunit of spindle-assembly checkpoint complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| HSP10 |
YOR020C |
Mitochondrial matrix co-chaperonin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ALY2 |
YJL084C |
Alpha arrestin, Ub-ligase adaptor for Rsp5p |
physical |
1 |
1 |
1 |
Biochemical Activity |
| CSM3 |
YMR048W |
Replication fork associated factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATG34 |
YOL083W |
Receptor protein involved in selective autophagy during starvation |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| AIM3 |
YBR108W |
Protein that inhibits barbed-end actin filament elongation |
physical |
1 |
1 |
1 |
Biochemical Activity |
| LAM6 |
YLR072W |
Sterol transporter that transfers sterols between membranes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| LAM6 |
YLR072W |
Sterol transporter that transfers sterols between membranes |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| GPN2 |
YOR262W |
Putative GTPase with a specific role in RNA pol II and polIII biogenes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ASK10 |
YGR097W |
Regulator of the Fps1p glycerol channel |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| APC11 |
YDL008W |
Catalytic core subunit, Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC27 |
YBL084C |
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COG7 |
YGL005C |
Component of the conserved oligomeric Golgi complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| ELP4 |
YPL101W |
Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| IPL1 |
YPL209C |
Aurora kinase of chromosomal passenger complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| AMD1 |
YML035C |
AMP deaminase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| IES4 |
YOR189W |
Component of the INO80 chromatiin remodeling complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| ATG23 |
YLR431C |
Peripheral membrane protein required for autophagy and CVT |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| ECO1 |
YFR027W |
Acetyltransferase required for sister chromatid cohesion |
physical |
1 |
1 |
1 |
Biochemical Activity |
| KAR3 |
YPR141C |
Minus-end-directed microtubule motor |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| KAR9 |
YPL269W |
Spindle positioning factor |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| CBF2 |
YGR140W |
Essential kinetochore protein |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| KAR2 |
YJL034W |
ATPase involved in protein import into the ER |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HIP1 |
YGR191W |
High-affinity histidine permease |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| ABF1 |
YKL112W |
DNA binding protein with possible chromatin-reorganizing activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EMC5 |
YIL027C |
Member of conserved ER transmembrane complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BUD6 |
YLR319C |
Actin- and formin-interacting protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| CAT8 |
YMR280C |
Zinc cluster transcriptional activator |
physical |
1 |
1 |
1 |
Biochemical Activity |
| GSY2 |
YLR258W |
Glycogen synthase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| DPH6 |
YLR143W |
Diphthamide synthetase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| CDC19 |
YAL038W |
Pyruvate kinase |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| CLA4 |
YNL298W |
Cdc42p-activated signal transducing kinase |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| DFG5 |
YMR238W |
Putative mannosidase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| CPR7 |
YJR032W |
Peptidyl-prolyl cis-trans isomerase (cyclophilin) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BCS1 |
YDR375C |
Protein translocase and chaperone required for Complex III assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DBP6 |
YNR038W |
Essential protein involved in ribosome biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AQR1 |
YNL065W |
Plasma membrane transporter of the major facilitator superfamily |
physical |
1 |
1 |
1 |
Biochemical Activity |
| ABZ1 |
YNR033W |
Para-aminobenzoate (PABA) synthase |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| DPM1 |
YPR183W |
Dolichol phosphate mannose (Dol-P-Man) synthase of ER membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AIM44 |
YPL158C |
Regulator of Cdc42p and Rho1p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| KIP2 |
YPL155C |
Kinesin-related motor protein involved in mitotic spindle positioning |
physical |
1 |
1 |
1 |
Biochemical Activity |
| ATP18 |
YML081C-A |
Subunit of the mitochondrial F1F0 ATP synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CSF1 |
YLR087C |
Protein with structural similarity to lipid transport protein Vps13p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DUS3 |
YLR401C |
Dihydrouridine synthase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| HUL4 |
YJR036C |
Protein with similarity to hect domain E3 ubiquitin-protein ligases |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| DCC1 |
YCL016C |
Subunit of a complex with Ctf8p and Ctf18p |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| BUL2 |
YML111W |
Alpha-arrestin, component of the Rsp5p E3-ubiquitin ligase complex |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| DDR48 |
YMR173W |
DNA damage-responsive protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ETR1 |
YBR026C |
2-enoyl thioester reductase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| ADH7 |
YCR105W |
NADPH-dependent medium chain alcohol dehydrogenase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| MBR1 |
YKL093W |
Protein involved in mitochondrial functions and stress response |
physical |
1 |
1 |
1 |
Biochemical Activity |
| MBR1 |
YKL093W |
Protein involved in mitochondrial functions and stress response |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| GIS2 |
YNL255C |
Translational activator for mRNAs with internal ribosome entry sites |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| GSH1 |
YJL101C |
Gamma glutamylcysteine synthetase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| IPT1 |
YDR072C |
Inositolphosphotransferase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| APJ1 |
YNL077W |
Hsp40 chaperone with a role in SUMO-mediated protein degradation |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| AIM29 |
YKR074W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AVT3 |
YKL146W |
Vacuolar transporter |
physical |
1 |
1 |
1 |
Biochemical Activity |
| CCW22 |
YDR134C |
Cell wall protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
| ADD37 |
YMR184W |
Protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
| CMR3 |
YPR013C |
Putative zinc finger protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
| GGC1 |
YDL198C |
Mitochondrial GTP/GDP transporter |
physical |
1 |
1 |
1 |
Biochemical Activity |
| EUG1 |
YDR518W |
Protein disulfide isomerase of the endoplasmic reticulum lumen |
physical |
1 |
1 |
1 |
Biochemical Activity |
| EMA35 |
YCR100C |
Protein involved in protein sorting |
physical |
1 |
1 |
1 |
Biochemical Activity |
| DUS1 |
YML080W |
Dihydrouridine synthase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| JJJ3 |
YJR097W |
Iron-binding protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| CYC2 |
YOR037W |
Mitochondrial peripheral inner membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CHS2 |
YBR038W |
Chitin synthase II |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| LDB18 |
YLL049W |
Component of the dynactin complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| ITR1 |
YDR497C |
Myo-inositol transporter |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| BAP2 |
YBR068C |
High-affinity leucine permease |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| HER2 |
YMR293C |
Subunit of the trimeric GatFAB AmidoTransferase(AdT) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CLB6 |
YGR109C |
B-type cyclin involved in DNA replication during S phase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| EFM5 |
YGR001C |
S-adenosylmethionine-dependent lysine methyltransferase |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| CDC1 |
YDR182W |
Putative mannose-ethanolamine phosphate phosphodiesterase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ERD2 |
YBL040C |
HDEL receptor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LAS21 |
YJL062W |
Mannose-ethanolamine phosphotransferase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| ITR2 |
YOL103W |
Myo-inositol transporter |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| EFM3 |
YJR129C |
S-adenosylmethionine-dependent methyltransferase |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| ENV9 |
YOR246C |
Conserved oxidoreductase involved in lipid droplet morphology |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
