| MEP1 |
YGR121C |
Ammonium permease |
genetic |
7 |
4 |
6 |
Synthetic Growth Defect, Synthetic Lethality, Phenotypic Suppression, Dosage Rescue, Synthetic Lethality, Synthetic Growth Defect, Dosage Rescue |
| MEP3 |
YPR138C |
Ammonium permease of high capacity and low affinity |
genetic |
6 |
3 |
5 |
Synthetic Growth Defect, Synthetic Lethality, Dosage Rescue, Synthetic Lethality, Synthetic Growth Defect, Dosage Rescue |
| MEP2 |
YNL142W |
Ammonium permease involved in regulation of pseudohyphal growth |
physical |
2 |
2 |
2 |
Affinity Capture-Western, Co-crystal Structure |
| HAP5 |
YOR358W |
Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| MSS11 |
YMR164C |
Transcription factor |
genetic |
2 |
1 |
2 |
Dosage Rescue, Dosage Rescue |
| MSN1 |
YOL116W |
Transcriptional activator |
genetic |
2 |
1 |
2 |
Dosage Rescue, Dosage Rescue |
| CBF5 |
YLR175W |
Pseudouridine synthase catalytic subunit of box H/ACA snoRNPs |
physical |
2 |
2 |
1 |
Two-hybrid, Affinity Capture-Western |
| GUP1 |
YGL084C |
Plasma membrane protein involved in remodeling GPI anchors |
physical |
2 |
2 |
1 |
Two-hybrid, Affinity Capture-Western |
| PHS1 |
YJL097W |
Essential 3-hydroxyacyl-CoA dehydratase of the ER membrane |
physical |
2 |
2 |
1 |
Two-hybrid, Affinity Capture-Western |
| VMA4 |
YOR332W |
Subunit E of the V1 domain of the vacuolar H+-ATPase (V-ATPase) |
physical |
2 |
2 |
1 |
Two-hybrid, Affinity Capture-Western |
| VTC1 |
YER072W |
Regulatory subunit of the vacuolar transporter chaperone (VTC) complex |
physical |
2 |
2 |
1 |
Two-hybrid, Affinity Capture-Western |
| VTC4 |
YJL012C |
Vacuolar membrane polyphosphate polymerase |
physical |
2 |
2 |
1 |
Two-hybrid, Affinity Capture-Western |
| SFP1 |
YLR403W |
Regulates transcription of ribosomal protein and biogenesis genes |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| IXR1 |
YKL032C |
Transcriptional repressor that regulates hypoxic genes during normoxia |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| SPT10 |
YJL127C |
Histone H3 acetylase with a role in transcriptional regulation |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| MET32 |
YDR253C |
Zinc-finger DNA-binding transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| TFC7 |
YOR110W |
RNA pol III transcription initiation factor complex (TFIIIC) subunit |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| RTG3 |
YBL103C |
bHLH/Zip transcription factor for retrograde (RTG) and TOR pathways |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| GZF3 |
YJL110C |
GATA zinc finger protein |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| NPR1 |
YNL183C |
Protein kinase |
regulation |
1 |
1 |
1 |
qualitative western immunoblotting evidence |
| GAT1 |
YFL021W |
Transcriptional activator of nitrogen catabolite repression genes |
regulation |
1 |
1 |
1 |
green fluorescent protein reporter gene assay evidence |
| NAB3 |
YPL190C |
RNA-binding protein, subunit of Nrd1 complex (Nrd1p-Nab3p-Sen1p) |
regulation |
1 |
1 |
1 |
quantitative reverse transcription polymerase chain reaction evidence |
| PSR1 |
YLL010C |
Plasma membrane-associated protein phosphatase |
regulation |
1 |
1 |
1 |
qualitative western immunoblotting evidence |
| PSR2 |
YLR019W |
Putative plasma membrane phosphatase |
regulation |
1 |
1 |
1 |
qualitative western immunoblotting evidence |
| MCM21 |
YDR318W |
Component of the kinetochore sub-complex COMA |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CBC2 |
YPL178W |
Small subunit of the heterodimeric cap binding complex with Sto1p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| COX6 |
YHR051W |
Subunit VI of cytochrome c oxidase (Complex IV) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LEA1 |
YPL213W |
Component of U2 snRNP complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| BUD21 |
YOR078W |
Component of small ribosomal subunit (SSU) processosome |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CDC6 |
YJL194W |
Essential ATP-binding protein required for DNA replication |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| ACE2 |
YLR131C |
Transcription factor required for septum destruction after cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DOT6 |
YER088C |
Protein involved in rRNA and ribosome biogenesis |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| DIA4 |
YHR011W |
Probable mitochondrial seryl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| DIP5 |
YPL265W |
Dicarboxylic amino acid permease |
physical |
1 |
1 |
1 |
PCA |
| KDX1 |
YKL161C |
Protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPA2 |
YER020W |
Nucleotide binding alpha subunit of the heterotrimeric G protein |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| CAF4 |
YKR036C |
WD40 repeat-containing protein associated with the CCR4-NOT complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FUI1 |
YBL042C |
High affinity uridine permease, localizes to the plasma membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ACO2 |
YJL200C |
Putative mitochondrial aconitase isozyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IPK1 |
YDR315C |
Inositol 1,3,4,5,6-pentakisphosphate 2-kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CBF1 |
YJR060W |
Basic helix-loop-helix (bHLH) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BUD8 |
YLR353W |
Protein involved in bud-site selection |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DAL80 |
YKR034W |
Negative regulator of genes in multiple nitrogen degradation pathways |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| GPR1 |
YDL035C |
Plasma membrane G protein coupled receptor (GPCR) |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| HMS1 |
YOR032C |
bHLH protein with similarity to myc-family transcription factors |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| GPB1 |
YOR371C |
Multistep regulator of cAMP-PKA signaling |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| HSP31 |
YDR533C |
Methylglyoxalase that converts methylglyoxal to D-lactate |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BAP3 |
YDR046C |
Amino acid permease |
genetic |
1 |
1 |
1 |
Positive Genetic |
| BOL3 |
YAL046C |
Protein involved in Fe-S cluster transfer to mitochondrial clients |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HRQ1 |
YDR291W |
3'-5' DNA helicase of the conserved RecQ family |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ADE16 |
YLR028C |
Enzyme of 'de novo' purine biosynthesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
| BNA1 |
YJR025C |
3-hydroxyanthranilic acid dioxygenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FCY1 |
YPR062W |
Cytosine deaminase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CYT1 |
YOR065W |
Cytochrome c1 |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HXT2 |
YMR011W |
High-affinity glucose transporter of the major facilitator superfamily |
physical |
1 |
1 |
1 |
Two-hybrid |
| SRO9 |
YCL037C |
Cytoplasmic RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| ZEO1 |
YOL109W |
Peripheral membrane protein of the plasma membrane |
physical |
1 |
1 |
1 |
Two-hybrid |
| PMT1 |
YDL095W |
Protein O-mannosyltransferase of the ER membrane |
physical |
1 |
1 |
1 |
Two-hybrid |
| PHD1 |
YKL043W |
Transcriptional activator that enhances pseudohyphal growth |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| MGA1 |
YGR249W |
Protein similar to heat shock transcription factor |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| TEC1 |
YBR083W |
Transcription factor targeting filamentation genes and Ty1 expression |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| MSS1 |
YMR023C |
Mitochondrial protein |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| SKN7 |
YHR206W |
Nuclear response regulator and transcription factor |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| MSN5 |
YDR335W |
Karyopherin |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| SSD1 |
YDR293C |
Translational repressor |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| URE2 |
YNL229C |
Nitrogen catabolite repression transcriptional regulator |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| PHB1 |
YGR132C |
Subunit of the prohibitin complex (Phb1p-Phb2p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MMF1 |
YIL051C |
Mitochondrial protein required for transamination of isoleucine |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SST2 |
YLR452C |
GTPase-activating protein for Gpa1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RAS2 |
YNL098C |
GTP-binding protein |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| PFK1 |
YGR240C |
Alpha subunit of heterooctameric phosphofructokinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TAL1 |
YLR354C |
Transaldolase, enzyme in the non-oxidative pentose phosphate pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPE2 |
YOL052C |
S-adenosylmethionine decarboxylase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ORT1 |
YOR130C |
Ornithine transporter of the mitochondrial inner membrane |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MET7 |
YOR241W |
Folylpolyglutamate synthetase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SWC5 |
YBR231C |
Component of the SWR1 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPS29B |
YDL061C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PEX5 |
YDR244W |
Peroxisomal membrane signal receptor for peroxisomal matrix proteins |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MIR1 |
YJR077C |
Mitochondrial phosphate carrier |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YJR084W |
YJR084W |
Protein that forms a complex with Thp3p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MLH1 |
YMR167W |
Protein required for mismatch repair in mitosis and meiosis |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PRP24 |
YMR268C |
Splicing factor that reanneals snRNPs during spliceosome recycling |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRPL27 |
YBR282W |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RIC1 |
YLR039C |
Protein involved in retrograde transport to the cis-Golgi network |
genetic |
1 |
1 |
1 |
Negative Genetic |
| URA7 |
YBL039C |
Major CTP synthase isozyme (see also URA8) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS8A |
YBL072C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SHE3 |
YBR130C |
Protein adaptor between Myo4p and the She2p-mRNA complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RIM1 |
YCR028C-A |
ssDNA-binding protein essential for mitochondrial genome maintenance |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SLX5 |
YDL013W |
Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PHM6 |
YDR281C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RAD54 |
YGL163C |
DNA-dependent ATPase that stimulates strand exchange |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRP13 |
YGR084C |
Mitochondrial ribosomal protein of the small subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YGR273C |
YGR273C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PTH1 |
YHR189W |
One of two mitochondrially-localized peptidyl-tRNA hydrolases |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TED1 |
YIL039W |
GPI-glycan remodelase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SDH9 |
YJL045W |
Minor succinate dehydrogenase isozyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL14A |
YKL006W |
Ribosomal 60S subunit protein L14A |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TPO5 |
YKL174C |
Protein involved in excretion of putrescine and spermidine |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MTD1 |
YKR080W |
NAD-dependent 5,10-methylenetetrahydrafolate dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SIC1 |
YLR079W |
Cyclin-dependent kinase inhibitor (CKI) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS18B |
YML026C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS9 |
YML097C |
Guanine nucleotide exchange factor (GEF) and ubiquitin receptor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NDI1 |
YML120C |
NADH:ubiquinone oxidoreductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| REC114 |
YMR133W |
Protein involved in early stages of meiotic recombination |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NDE1 |
YMR145C |
Mitochondrial external NADH dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YMR160W |
YMR160W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YMR316C-A |
YMR316C-A |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL43A |
YPR043W |
Ribosomal 60S subunit protein L43A |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YPR063C |
YPR063C |
ER-localized protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NPR1 |
YNL183C |
Protein kinase |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| SGS1 |
YMR190C |
RecQ family nucleolar DNA helicase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| EFM4 |
YIL064W |
Lysine methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HMS2 |
YJR147W |
Protein with similarity to heat shock transcription factors |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| LST4 |
YKL176C |
Subunit of the Lst4p-Lst7p GTPase activating protein complex for Gtr2p |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| FMT1 |
YBL013W |
Methionyl-tRNA formyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
