UTP10 |
YJL109C |
Nucleolar protein |
physical |
7 |
3 |
6 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, Affinity Capture-Western |
UTP22 |
YGR090W |
Component of the small-subunit processome |
physical |
7 |
3 |
5 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Two-hybrid, Affinity Capture-Western |
UTP6 |
YDR449C |
Nucleolar protein |
physical |
7 |
3 |
4 |
Affinity Capture-MS, Affinity Capture-Western, Two-hybrid, Affinity Capture-Western, Two-hybrid, Two-hybrid, Affinity Capture-Western |
IMP4 |
YNL075W |
Component of the SSU processome |
physical |
7 |
3 |
4 |
Affinity Capture-Western, Two-hybrid, Two-hybrid, Affinity Capture-MS, Two-hybrid, Two-hybrid, Affinity Capture-Western |
IMP3 |
YHR148W |
Component of the SSU processome |
physical |
7 |
4 |
3 |
Affinity Capture-Western, Two-hybrid, Co-crystal Structure, Reconstituted Complex, Two-hybrid, Two-hybrid, Affinity Capture-Western |
UTP7 |
YER082C |
Nucleolar protein |
physical |
6 |
2 |
6 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western |
KRR1 |
YCL059C |
Nucleolar protein required for rRNA synthesis and ribosomal assembly |
physical |
6 |
2 |
5 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS |
UTP25 |
YIL091C |
Nucleolar protein |
physical |
6 |
3 |
4 |
Affinity Capture-MS, Two-hybrid, Affinity Capture-Western, Two-hybrid, Two-hybrid, Affinity Capture-Western |
SAS10 |
YDL153C |
Subunit of U3-containing Small Subunit (SSU) processome complex |
physical |
6 |
3 |
3 |
Affinity Capture-MS, Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Affinity Capture-Western |
ENP1 |
YBR247C |
Protein associated with U3 and U14 snoRNAs |
physical |
5 |
2 |
5 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS |
PWP2 |
YCR057C |
Conserved 90S pre-ribosomal component |
physical |
5 |
1 |
5 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
NOP14 |
YDL148C |
Nucleolar protein |
physical |
4 |
2 |
4 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Two-hybrid |
UTP14 |
YML093W |
Subunit of U3-containing Small Subunit (SSU) processome complex |
physical |
4 |
2 |
4 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS |
UTP8 |
YGR128C |
Nucleolar protein required for export of tRNAs from the nucleus |
physical |
4 |
2 |
4 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western |
UTP9 |
YHR196W |
Nucleolar protein |
physical |
4 |
2 |
4 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western |
NOP58 |
YOR310C |
Protein involved in producing mature rRNAs and snoRNAs |
physical |
4 |
1 |
4 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
NOC4 |
YPR144C |
Nucleolar protein |
physical |
4 |
2 |
3 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS |
UTP21 |
YLR409C |
Subunit of U3-containing 90S preribosome and SSU processome complexes |
physical |
4 |
2 |
3 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS |
ECM16 |
YMR128W |
Essential DEAH-box ATP-dependent RNA helicase specific to U3 snoRNP |
physical |
3 |
2 |
3 |
Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS |
NOP1 |
YDL014W |
Histone glutamine methyltransferase, modifies H2A at Q105 in nucleolus |
physical |
3 |
2 |
3 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western |
RRP9 |
YPR137W |
Protein involved in pre-rRNA processing |
physical |
3 |
2 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western |
HSP82 |
YPL240C |
Hsp90 chaperone |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
BUD21 |
YOR078W |
Component of small ribosomal subunit (SSU) processosome |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
UTP18 |
YJL069C |
Small-subunit processome protein involved in pre-18S rRNA maturation |
physical |
3 |
2 |
2 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western |
HAS1 |
YMR290C |
ATP-dependent RNA helicase |
physical |
3 |
2 |
1 |
Two-hybrid, Two-hybrid, Affinity Capture-Western |
UTP15 |
YMR093W |
Nucleolar protein |
physical |
2 |
2 |
2 |
Affinity Capture-MS, Affinity Capture-Western |
UTP5 |
YDR398W |
Subunit of U3-containing Small Subunit (SSU) processome complex |
physical |
2 |
2 |
2 |
Affinity Capture-MS, Affinity Capture-Western |
RPS2 |
YGL123W |
Protein component of the small (40S) subunit |
physical |
2 |
2 |
2 |
Affinity Capture-Western, Affinity Capture-MS |
RPS6A |
YPL090C |
Protein component of the small (40S) ribosomal subunit |
physical |
2 |
2 |
2 |
Affinity Capture-Western, Affinity Capture-MS |
RPS7A |
YOR096W |
Protein component of the small (40S) ribosomal subunit |
physical |
2 |
2 |
2 |
Affinity Capture-Western, Affinity Capture-MS |
RPS9A |
YPL081W |
Protein component of the small (40S) ribosomal subunit |
physical |
2 |
2 |
2 |
Affinity Capture-Western, Affinity Capture-MS |
DHR2 |
YKL078W |
Predominantly nucleolar DEAH-box ATP-dependent RNA helicase |
physical |
2 |
2 |
2 |
Affinity Capture-Western, Two-hybrid |
RRP5 |
YMR229C |
RNA binding protein involved in synthesis of 18S and 5.8S rRNAs |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
UTP4 |
YDR324C |
Subunit of U3-containing 90S preribosome and SSU processome complexes |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
SSA1 |
YAL005C |
ATPase involved in protein folding and NLS-directed nuclear transport |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
EMG1 |
YLR186W |
Methyltransferase for rRNA |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
UTP20 |
YBL004W |
Component of the small-subunit (SSU) processome |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
MRD1 |
YPR112C |
Essential conserved small ribosomal subunit (40s) synthesis factor |
genetic |
2 |
2 |
1 |
Synthetic Growth Defect, Phenotypic Enhancement |
MPP10 |
YJR002W |
Component of the SSU processome and 90S preribosome |
physical |
2 |
2 |
1 |
Two-hybrid, Affinity Capture-Western |
BFR2 |
YDR299W |
Component of the SSU and 90S preribosomes |
physical |
2 |
1 |
1 |
Affinity Capture-Western, Affinity Capture-Western |
ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
genetic |
2 |
1 |
1 |
Synthetic Haploinsufficiency, Synthetic Haploinsufficiency |
SFP1 |
YLR403W |
Regulates transcription of ribosomal protein and biogenesis genes |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
RFX1 |
YLR176C |
Major transcriptional repressor of DNA-damage-regulated genes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
STP1 |
YDR463W |
Transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
YAP6 |
YDR259C |
Basic leucine zipper (bZIP) transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
UME6 |
YDR207C |
Rpd3L histone deacetylase complex subunit |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RAD53 |
YPL153C |
DNA damage response kinase |
regulation |
1 |
1 |
1 |
protein kinase assay evidence |
ENP2 |
YGR145W |
Component of the SSU |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
DIP2 |
YLR129W |
Nucleolar protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MAK21 |
YDR060W |
Constituent of 66S pre-ribosomal particles |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HCA4 |
YJL033W |
DEAD box RNA helicase |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
CSL4 |
YNL232W |
Exosome non-catalytic core component |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
BMS1 |
YPL217C |
GTPase required for ribosomal subunit synthesis and rRNA processing |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ASC1 |
YMR116C |
G-protein beta subunit and guanine dissociation inhibitor for Gpa2p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CDC3 |
YLR314C |
Component of the septin ring that is required for cytokinesis |
physical |
1 |
1 |
1 |
Two-hybrid |
DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
NAN1 |
YPL126W |
U3 snoRNP protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
UTP11 |
YKL099C |
Subunit of U3-containing Small Subunit (SSU) processome complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
UTP13 |
YLR222C |
Nucleolar protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
UTP6 |
YDR449C |
Nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS6B |
YBR181C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
RPS7B |
YNL096C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
RPS9B |
YBR189W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
RPS14A |
YCR031C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
RPS14B |
YJL191W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
UGP1 |
YKL035W |
UDP-glucose pyrophosphorylase (UGPase) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NPL6 |
YMR091C |
Component of the RSC chromatin remodeling complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PRP4 |
YPR178W |
Splicing factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RTT107 |
YHR154W |
BRCA1 C-terminal domain protein needed for recovery from DNA damage |
physical |
1 |
1 |
1 |
Two-hybrid |
UTP23 |
YOR004W |
Component of the small subunit processome |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
NOP9 |
YJL010C |
Essential subunit of U3-containing 90S preribosome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NOP15 |
YNL110C |
Constituent of 66S pre-ribosomal particles |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RRP3 |
YHR065C |
Protein involved in rRNA processing |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
ROK1 |
YGL171W |
RNA-dependent ATPase |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
SMY1 |
YKL079W |
Kinesin-like myosin passenger-protein |
physical |
1 |
1 |
1 |
Two-hybrid |
STB2 |
YMR053C |
Protein that interacts with Sin3p in a two-hybrid assay |
physical |
1 |
1 |
1 |
Two-hybrid |
TYE7 |
YOR344C |
Serine-rich protein that contains a bHLH DNA binding motif |
physical |
1 |
1 |
1 |
Two-hybrid |
NIP100 |
YPL174C |
Large subunit of the dynactin complex |
physical |
1 |
1 |
1 |
Two-hybrid |
MRD1 |
YPR112C |
Essential conserved small ribosomal subunit (40s) synthesis factor |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
ULP2 |
YIL031W |
Peptidase that deconjugates Smt3/SUMO-1 peptides from proteins |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NMD2 |
YHR077C |
Protein involved in the nonsense-mediated mRNA decay (NMD) pathway |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SSB2 |
YNL209W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
1 |
1 |
1 |
Co-purification |
TOM1 |
YDR457W |
E3 ubiquitin ligase of the hect-domain class |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPC82 |
YPR190C |
RNA polymerase III subunit C82 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RET1 |
YOR207C |
Second-largest subunit of RNA polymerase III |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SGD1 |
YLR336C |
Essential nuclear protein |
physical |
1 |
1 |
1 |
Two-hybrid |
RPS1A |
YLR441C |
Ribosomal protein of the small (40S) subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS8A |
YBL072C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS12 |
YOR369C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS15 |
YOL040C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS17A |
YML024W |
Ribosomal protein 51 (rp51) of the small (40s) subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS18A |
YDR450W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS22A |
YJL190C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL26A |
YLR344W |
Ribosomal 60S subunit protein L26A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL31A |
YDL075W |
Ribosomal 60S subunit protein L31A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS3 |
YNL178W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RRP6 |
YOR001W |
Nuclear exosome exonuclease component |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TRF5 |
YNL299W |
Non-canonical poly(A) polymerase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PEX5 |
YDR244W |
Peroxisomal membrane signal receptor for peroxisomal matrix proteins |
genetic |
1 |
1 |
1 |
Negative Genetic |
RTT103 |
YDR289C |
Protein involved in transcription termination by RNA polymerase II |
genetic |
1 |
1 |
1 |
Negative Genetic |
REE1 |
YJL217W |
Cytoplasmic protein involved in the regulation of enolase (ENO1) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SAC1 |
YKL212W |
Phosphatidylinositol phosphate phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SIC1 |
YLR079W |
Cyclin-dependent kinase inhibitor (CKI) |
genetic |
1 |
1 |
1 |
Negative Genetic |
RAS2 |
YNL098C |
GTP-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
YPR089W |
YPR089W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
NOP6 |
YDL213C |
rRNA-binding protein required for 40S ribosomal subunit biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
CRM1 |
YGR218W |
Nuclear export factor, exportin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HDA2 |
YDR295C |
Subunit of HDA1 histone deacetylase complex |
physical |
1 |
1 |
1 |
Two-hybrid |
DBP8 |
YHR169W |
ATPase, putative RNA helicase of the DEAD-box family |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
ESF2 |
YNR054C |
Essential nucleolar protein involved in pre-18S rRNA processing |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CMS1 |
YLR003C |
Putative subunit of the 90S preribosome processome complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
AIR1 |
YIL079C |
Zinc knuckle protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GBP2 |
YCL011C |
Poly(A+) RNA-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
FCF1 |
YDR339C |
PINc domain endonuclease |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
FCF1 |
YDR339C |
PINc domain endonuclease |
genetic |
1 |
1 |
1 |
Negative Genetic |
MMS22 |
YLR320W |
Subunit of E3 ubiquitin ligase complex involved in replication repair |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MLP2 |
YIL149C |
Myosin-like protein associated with the nuclear envelope |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GZF3 |
YJL110C |
GATA zinc finger protein |
physical |
1 |
1 |
1 |
Two-hybrid |
ASK10 |
YGR097W |
Regulator of the Fps1p glycerol channel |
genetic |
1 |
1 |
1 |
Positive Genetic |
BIK1 |
YCL029C |
Microtubule-associated protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
KAR2 |
YJL034W |
ATPase involved in protein import into the ER |
physical |
1 |
1 |
1 |
Two-hybrid |
HMT1 |
YBR034C |
Nuclear SAM-dependent mono- and asymmetric methyltransferase |
physical |
1 |
1 |
1 |
Biochemical Activity |
FAF1 |
YIL019W |
Protein required for pre-rRNA processing |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MOG1 |
YJR074W |
Conserved nuclear protein that interacts with GTP-Gsp1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HBS1 |
YKR084C |
GTPase with similarity to translation release factors |
genetic |
1 |
1 |
1 |
Negative Genetic |
BUD23 |
YCR047C |
Ribosome biogenesis factor |
physical |
1 |
1 |
1 |
Co-fractionation |
HRQ1 |
YDR291W |
3'-5' DNA helicase of the conserved RecQ family |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BUL2 |
YML111W |
Alpha-arrestin, component of the Rsp5p E3-ubiquitin ligase complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ELF1 |
YKL160W |
Transcription elongation factor with a conserved zinc finger domain |
genetic |
1 |
1 |
1 |
Negative Genetic |
GIS2 |
YNL255C |
Translational activator for mRNAs with internal ribosome entry sites |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
APJ1 |
YNL077W |
Hsp40 chaperone with a role in SUMO-mediated protein degradation |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MAK31 |
YCR020C-A |
Non-catalytic subunit of N-terminal acetyltransferase of the NatC type |
genetic |
1 |
1 |
1 |
Negative Genetic |
MCT1 |
YOR221C |
Predicted malonyl-CoA:ACP transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |