Standard name Systematic name Name description Description
NUP170 YBL079W Subunit of inner ring of nuclear pore complex (NPC) Subunit of inner ring of nuclear pore complex (NPC); contributes to NPC assembly and nucleocytoplasmic transport; interacts with genomic regions that contain ribosomal protein and subtelomeric genes, where it functions in nucleosome positioning and as a repressor of transcription; both Nup170p and Nup157p are similar to human Nup155p; NUP170 has a paralog, NUP157, that arose from the whole genome duplication
Visualize the interactome of NUP170
Links to external databases:
SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Nuc Periphery 0.779 0.810 0.802
Nucleolus 0.063 0.066 0.121
Vac/Vac Memb 0.426 0.328 0.240
Mito NaN 0.058 0.145

GFP localization & abundance

GFP localization GFP abundance
nuclear periphery 1560

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
NUP170 0 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
NUP53 YMR153W FG-nucleoporin component of central core of nuclear pore complex (NPC) physical 8 3 6 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-Western
NUP157 YER105C Subunit of the inner ring of the nuclear pore complex (NPC) genetic 7 6 6 Synthetic Lethality, Synthetic Rescue, Synthetic Growth Defect, Phenotypic Enhancement, Dosage Rescue, Synthetic Growth Defect, Negative Genetic
POM152 YMR129W Glycoprotein subunit of transmembrane ring of nuclear pore complex genetic 6 3 5 Synthetic Lethality, Synthetic Lethality, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic
POM34 YLR018C Subunit of the transmembrane ring of the nuclear pore complex (NPC) genetic 6 3 5 Synthetic Lethality, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Synthetic Lethality
NUP2 YLR335W Nucleoporin involved in nucleocytoplasmic transport genetic 6 3 5 Synthetic Lethality, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic
NUP133 YKR082W Subunit of Nup84p subcomplex of nuclear pore complex (NPC) genetic 5 3 4 Synthetic Lethality, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic
SAC3 YDR159W mRNA export factor genetic 4 3 4 Phenotypic Enhancement, Negative Genetic, Synthetic Growth Defect, Negative Genetic
APQ12 YIL040W Nuclear envelope/ER integral membrane protein genetic 4 2 4 Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
NUP84 YDL116W Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) physical 4 1 4 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 4 3 3 Synthetic Growth Defect, Synthetic Growth Defect, Positive Genetic, Negative Genetic
NUP145 YGL092W Essential protein with distinct roles in two nuclear pore subcomplexes physical 4 2 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex
NUP53 YMR153W FG-nucleoporin component of central core of nuclear pore complex (NPC) genetic 4 2 3 Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic
NUP188 YML103C Subunit of the inner ring of the nuclear pore complex (NPC) genetic 4 2 3 Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic
NUP100 YKL068W FG-nucleoporin component of central core of the nuclear pore complex physical 4 2 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex
MPS3 YJL019W Nuclear envelope protein genetic 4 2 2 Synthetic Rescue, Synthetic Rescue, Synthetic Growth Defect, Synthetic Growth Defect
HTZ1 YOL012C Histone variant H2AZ genetic 3 3 3 Phenotypic Enhancement, Negative Genetic, Synthetic Growth Defect
NUP116 YMR047C FG-nucleoporin component of central core of the nuclear pore complex physical 3 3 3 Co-purification, Affinity Capture-MS, Reconstituted Complex
ASM4 YDL088C FG-nucleoporin component of central core of nuclear pore complex (NPC) physical 3 3 3 Affinity Capture-Western, Reconstituted Complex, Affinity Capture-MS
ARX1 YDR101C Nuclear export factor for the ribosomal pre-60S subunit genetic 3 2 3 Negative Genetic, Synthetic Growth Defect, Negative Genetic
NUP1 YOR098C FG-nucleoporin component of central core of the nuclear pore complex physical 3 2 3 Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western
ASM4 YDL088C FG-nucleoporin component of central core of nuclear pore complex (NPC) genetic 3 2 3 Negative Genetic, Synthetic Growth Defect, Negative Genetic
PBP1 YGR178C Component of glucose deprivation induced stress granules genetic 3 2 3 Positive Genetic, Negative Genetic, Negative Genetic
DED81 YHR019C Cytosolic asparaginyl-tRNA synthetase genetic 3 2 2 Positive Genetic, Negative Genetic, Negative Genetic
KAP95 YLR347C Karyopherin beta genetic 3 2 2 Synthetic Lethality, Negative Genetic, Negative Genetic
ITC1 YGL133W Subunit of ATP-dependent Isw2p-Itc1p chromatin remodeling complex genetic 3 2 2 Synthetic Growth Defect, Negative Genetic, Negative Genetic
RNA1 YMR235C GTPase activating protein (GAP) for Gsp1p genetic 3 2 2 Dosage Lethality, Negative Genetic, Negative Genetic
SNL1 YIL016W Ribosome-associated protein genetic 3 2 2 Synthetic Growth Defect, Negative Genetic, Negative Genetic
NUP100 YKL068W FG-nucleoporin component of central core of the nuclear pore complex genetic 3 2 2 Positive Genetic, Synthetic Rescue, Synthetic Rescue
SIR4 YDR227W SIR protein involved in assembly of silent chromatin domains physical 3 1 2 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western
NUP60 YAR002W FG-nucleoporin component of central core of the nuclear pore complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SLX9 YGR081C Protein required for pre-rRNA processing genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
FKH1 YIL131C Forkhead family transcription factor regulation 2 2 2 chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments
NPL3 YDR432W RNA-binding protein genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
NUP120 YKL057C Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) genetic 2 2 2 Synthetic Lethality, Synthetic Growth Defect
NTF2 YER009W Nuclear envelope protein genetic 2 2 2 Dosage Lethality, Negative Genetic
ARP6 YLR085C Actin-related protein that binds nucleosomes genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
NUP82 YJL061W Linker nucleoporin component of the nuclear pore complex (NPC) genetic 2 2 2 Synthetic Lethality, Negative Genetic
NUP42 YDR192C FG-nucleoporin component of central core of the nuclear pore complex genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
SAP30 YMR263W Component of Rpd3L histone deacetylase complex genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
SRO9 YCL037C Cytoplasmic RNA-binding protein genetic 2 2 2 Positive Genetic, Synthetic Growth Defect
SUP35 YDR172W Translation termination factor eRF3 genetic 2 2 2 Positive Genetic, Negative Genetic
TCP1 YDR212W Alpha subunit of chaperonin-containing T-complex genetic 2 2 2 Synthetic Lethality, Negative Genetic
SEC28 YIL076W Epsilon-COP subunit of the coatomer genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
MAM1 YER106W Monopolin genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
ARC1 YGL105W Protein that binds tRNA and methionyl- and glutamyl-tRNA synthetases genetic 2 1 2 Negative Genetic, Negative Genetic
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
BEM1 YBR200W Protein containing SH3-domains genetic 2 1 2 Negative Genetic, Negative Genetic
ECM1 YAL059W Pre-ribosomal factor involved in 60S ribosomal protein subunit export genetic 2 1 2 Negative Genetic, Negative Genetic
CSE1 YGL238W Nuclear envelope protein that acts as a recycling factor genetic 2 1 2 Negative Genetic, Negative Genetic
BGL2 YGR282C Endo-beta-1,3-glucanase genetic 2 1 2 Negative Genetic, Negative Genetic
GRS1 YBR121C Cytoplasmic and mitochondrial glycyl-tRNA synthase genetic 2 1 2 Negative Genetic, Negative Genetic
NUP1 YOR098C FG-nucleoporin component of central core of the nuclear pore complex genetic 2 1 2 Synthetic Lethality, Synthetic Lethality
NDC1 YML031W Subunit of the transmembrane ring of the nuclear pore complex (NPC) physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
ATG8 YBL078C Ub-like protein physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
DBP5 YOR046C Cytoplasmic ATP-dependent RNA helicase of the DEAD-box family genetic 2 1 2 Negative Genetic, Negative Genetic
MEX67 YPL169C Poly(A)RNA binding protein involved in nuclear mRNA export physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
MEX67 YPL169C Poly(A)RNA binding protein involved in nuclear mRNA export genetic 2 1 2 Negative Genetic, Negative Genetic
RIT1 YMR283C Initiator methionine 2'-O-ribosyl phosphate transferase genetic 2 1 2 Negative Genetic, Negative Genetic
NUP57 YGR119C FG-nucleoporin component of central core of the nuclear pore complex genetic 2 1 2 Negative Genetic, Negative Genetic
OTU1 YFL044C Deubiquitylation enzyme that binds to the chaperone-ATPase Cdc48p genetic 2 1 2 Positive Genetic, Positive Genetic
ORM1 YGR038W Protein that mediates sphingolipid homeostasis genetic 2 1 2 Negative Genetic, Negative Genetic
YKL069W YKL069W Methionine-R-sulfoxide reductase genetic 2 1 2 Negative Genetic, Negative Genetic
TGS1 YPL157W Trimethyl guanosine synthase, conserved nucleolar methyl transferase genetic 2 1 2 Negative Genetic, Negative Genetic
POM33 YLL023C Transmembrane nucleoporin genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
LRS4 YDR439W Nucleolar protein that forms a complex with Csm1p genetic 2 1 2 Positive Genetic, Positive Genetic
MOG1 YJR074W Conserved nuclear protein that interacts with GTP-Gsp1p genetic 2 1 2 Negative Genetic, Negative Genetic
NKP2 YLR315W Central kinetochore protein and subunit of the Ctf19 complex genetic 2 1 2 Negative Genetic, Negative Genetic
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 2 2 1 Positive Genetic, Negative Genetic
EXO70 YJL085W Subunit of the exocyst complex genetic 2 2 1 Positive Genetic, Negative Genetic
MOB2 YFL034C-B Activator of Cbk1p kinase genetic 2 2 1 Positive Genetic, Negative Genetic
UTP8 YGR128C Nucleolar protein required for export of tRNAs from the nucleus physical 2 2 1 Affinity Capture-MS, Affinity Capture-Western
YAF9 YNL107W Subunit of NuA4 histone H4 acetyltransferase and SWR1 complexes genetic 2 2 1 Synthetic Growth Defect, Synthetic Lethality
NSL1 YPL233W Essential component of the MIND kinetochore complex genetic 2 1 1 Negative Genetic, Negative Genetic
CDC11 YJR076C Component of the septin ring that is required for cytokinesis genetic 2 1 1 Negative Genetic, Negative Genetic
CDC12 YHR107C Component of the septin ring that is required for cytokinesis genetic 2 1 1 Negative Genetic, Negative Genetic
EMG1 YLR186W Methyltransferase for rRNA genetic 2 1 1 Negative Genetic, Negative Genetic
NUP145 YGL092W Essential protein with distinct roles in two nuclear pore subcomplexes genetic 2 1 1 Negative Genetic, Negative Genetic
CDC20 YGL116W Activator of anaphase-promoting complex/cyclosome (APC/C) genetic 2 1 1 Negative Genetic, Negative Genetic
GLE1 YDL207W Cytoplasmic nucleoporin required for polyadenylated mRNA export genetic 2 1 1 Negative Genetic, Negative Genetic
ESS1 YJR017C Peptidylprolyl-cis/trans-isomerase (PPIase) genetic 2 1 1 Negative Genetic, Negative Genetic
APC5 YOR249C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 2 1 1 Negative Genetic, Negative Genetic
MPS1 YDL028C Dual-specificity kinase genetic 2 1 1 Negative Genetic, Negative Genetic
POM152 YMR129W Glycoprotein subunit of transmembrane ring of nuclear pore complex physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
STH1 YIL126W ATPase component of the RSC chromatin remodeling complex physical 2 1 1 Affinity Capture-Western, Affinity Capture-Western
YRB1 YDR002W Ran GTPase binding protein genetic 2 1 1 Negative Genetic, Negative Genetic
SCC2 YDR180W Subunit of cohesin loading factor (Scc2p-Scc4p) genetic 2 1 1 Negative Genetic, Negative Genetic
SMT3 YDR510W Ubiquitin-like protein of the SUMO family genetic 2 1 1 Negative Genetic, Negative Genetic
PRE4 YFR050C Beta 7 subunit of the 20S proteasome genetic 2 1 1 Negative Genetic, Negative Genetic
RPN12 YFR052W Subunit of the 19S regulatory particle of the 26S proteasome lid genetic 2 1 1 Negative Genetic, Negative Genetic
OKP1 YGR179C Outer kinetochore protein required for accurate chromosome segregation genetic 2 1 1 Negative Genetic, Negative Genetic
UTP9 YHR196W Nucleolar protein genetic 2 1 1 Negative Genetic, Negative Genetic
STS1 YIR011C Protein required for localizing proteasomes to the nucleus genetic 2 1 1 Negative Genetic, Negative Genetic
RPT4 YOR259C ATPase of the 19S regulatory particle of the 26S proteasome genetic 2 1 1 Negative Genetic, Negative Genetic
BRR6 YGL247W Essential nuclear envelope integral membrane protein genetic 2 1 1 Negative Genetic, Negative Genetic
CDC8 YJR057W Nucleoside monophosphate and nucleoside diphosphate kinase genetic 2 1 1 Negative Genetic, Negative Genetic
SPT10 YJL127C Histone H3 acetylase with a role in transcriptional regulation regulation 1 1 1 DNA to cDNA expression microarray evidence
FKH2 YNL068C Forkhead family transcription factor regulation 1 1 1 ChEC-Seq experiments
XBP1 YIL101C Transcriptional repressor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ABF1 YKL112W DNA binding protein with possible chromatin-reorganizing activity regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SUA7 YPR086W Transcription factor TFIIB regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CDC73 YLR418C Component of the Paf1p complex genetic 1 1 1 Negative Genetic
CEF1 YMR213W Essential splicing factor genetic 1 1 1 Positive Genetic
DSN1 YIR010W Essential component of the outer kinetochore MIND complex genetic 1 1 1 Negative Genetic
MTW1 YAL034W-A Essential component of the MIND kinetochore complex genetic 1 1 1 Negative Genetic
GLC7 YER133W Type 1 S/T protein phosphatase (PP1) catalytic subunit genetic 1 1 1 Positive Genetic
DBP9 YLR276C DEAD-box protein required for 27S rRNA processing genetic 1 1 1 Positive Genetic
NOP2 YNL061W rRNA m5C methyltransferase genetic 1 1 1 Positive Genetic
KAP123 YER110C Karyopherin beta genetic 1 1 1 Negative Genetic
BRR2 YER172C RNA-dependent ATPase RNA helicase (DEIH box) genetic 1 1 1 Negative Genetic
NSE4 YDL105W Component of the SMC5-SMC6 complex genetic 1 1 1 Positive Genetic
BRE1 YDL074C E3 ubiquitin ligase genetic 1 1 1 Synthetic Growth Defect
NUG1 YER006W GTPase that associates with nuclear 60S pre-ribosomes genetic 1 1 1 Positive Genetic
MRT4 YKL009W Protein involved in mRNA turnover and ribosome assembly genetic 1 1 1 Negative Genetic
GUS1 YGL245W Glutamyl-tRNA synthetase (GluRS) genetic 1 1 1 Negative Genetic
DBP3 YGL078C RNA-Dependent ATPase, member of DExD/H-box family genetic 1 1 1 Positive Genetic
DBP7 YKR024C Putative ATP-dependent RNA helicase of the DEAD-box family genetic 1 1 1 Negative Genetic
LSM3 YLR438C-A Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
LSM6 YDR378C Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
DED1 YOR204W ATP-dependent DEAD-box RNA helicase with strand-annealing activity genetic 1 1 1 Negative Genetic
CDC48 YDL126C AAA ATPase with protein-unfoldase activity genetic 1 1 1 Negative Genetic
CSL4 YNL232W Exosome non-catalytic core component genetic 1 1 1 Negative Genetic
LRP1 YHR081W Nuclear exosome-associated nucleic acid binding protein genetic 1 1 1 Positive Genetic
GCD11 YER025W Gamma subunit of the translation initiation factor eIF2 genetic 1 1 1 Positive Genetic
MED7 YOL135C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
GCD1 YOR260W Gamma subunit of the translation initiation factor eIF2B genetic 1 1 1 Negative Genetic
CFT2 YLR115W Subunit of the mRNA cleavage and polyadenlylation factor (CPF) genetic 1 1 1 Positive Genetic
IMD3 YLR432W Inosine monophosphate dehydrogenase genetic 1 1 1 Negative Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
CDC39 YCR093W Subunit of the CCR4-NOT1 core complex genetic 1 1 1 Negative Genetic
ARP3 YJR065C Essential component of the Arp2/3 complex genetic 1 1 1 Negative Genetic
CTF18 YMR078C Subunit of a complex with Ctf8p genetic 1 1 1 Synthetic Growth Defect
CTK1 YKL139W Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) genetic 1 1 1 Negative Genetic
DCP1 YOL149W Subunit of the Dcp1p-Dcp2p decapping enzyme complex genetic 1 1 1 Negative Genetic
CDC23 YHR166C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Negative Genetic
ESP1 YGR098C Separase/separin, a caspase-like cysteine protease genetic 1 1 1 Negative Genetic
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
IRR1 YIL026C Subunit of the cohesin complex genetic 1 1 1 Negative Genetic
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
KGD2 YDR148C Dihydrolipoyl transsuccinylase genetic 1 1 1 Negative Genetic
MRD1 YPR112C Essential conserved small ribosomal subunit (40s) synthesis factor genetic 1 1 1 Negative Genetic
LAS17 YOR181W Actin assembly factor genetic 1 1 1 Positive Genetic
CRM1 YGR218W Nuclear export factor, exportin genetic 1 1 1 Negative Genetic
LCB1 YMR296C Component of serine palmitoyltransferase genetic 1 1 1 Negative Genetic
LSM7 YNL147W Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
LST8 YNL006W Protein required for the transport of Gap1p genetic 1 1 1 Positive Genetic
MCD1 YDL003W Essential alpha-kleisin subunit of the cohesin complex genetic 1 1 1 Negative Genetic
COG3 YER157W Essential component of the conserved oligomeric Golgi complex genetic 1 1 1 Positive Genetic
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family genetic 1 1 1 Synthetic Growth Defect
HRR25 YPL204W Conserved casein kinase, monopolin subunit genetic 1 1 1 Positive Genetic
MEC1 YBR136W Genome integrity checkpoint protein and PI kinase superfamily member genetic 1 1 1 Negative Genetic
CMR1 YDL156W Nuclear protein with role in transcription, protein quality control physical 1 1 1 Affinity Capture-MS
MTR10 YOR160W Nuclear import receptor genetic 1 1 1 Negative Genetic
MLC1 YGL106W Essential light chain for Myo1p physical 1 1 1 Affinity Capture-MS
NAM8 YHR086W RNA binding protein, component of the U1 snRNP protein genetic 1 1 1 Negative Genetic
ARP8 YOR141C Nuclear actin-related protein involved in chromatin remodeling genetic 1 1 1 Negative Genetic
NIC96 YFR002W Linker nucleoporin component of the nuclear pore complex (NPC) physical 1 1 1 Affinity Capture-MS
NSP1 YJL041W FG-nucleoporin component of central core of the nuclear pore complex physical 1 1 1 Reconstituted Complex
NSP1 YJL041W FG-nucleoporin component of central core of the nuclear pore complex genetic 1 1 1 Negative Genetic
NUP116 YMR047C FG-nucleoporin component of central core of the nuclear pore complex genetic 1 1 1 Negative Genetic
NUP159 YIL115C FG-nucleoporin component of central core of the nuclear pore complex genetic 1 1 1 Negative Genetic
AFG2 YLR397C ATPase of the CDC48/PAS1/SEC18 (AAA) family, forms a hexameric complex genetic 1 1 1 Negative Genetic
HSP82 YPL240C Hsp90 chaperone genetic 1 1 1 Synthetic Growth Defect
GLE2 YER107C RNA export factor associated with the nuclear pore complex (NPC) physical 1 1 1 Affinity Capture-MS
GLE2 YER107C RNA export factor associated with the nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
DAM1 YGR113W Essential subunit of the Dam1 complex (aka DASH complex) genetic 1 1 1 Negative Genetic
NOP14 YDL148C Nucleolar protein genetic 1 1 1 Negative Genetic
GPT2 YKR067W Glycerol-3-phosphate/dihydroxyacetone phosphate sn-1 acyltransferase genetic 1 1 1 Negative Genetic
MED8 YBR193C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
DEP1 YAL013W Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Synthetic Growth Defect
MTR3 YGR158C Exosome non-catalytic core component genetic 1 1 1 Negative Genetic
NUP120 YKL057C Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) physical 1 1 1 Affinity Capture-MS
HOS2 YGL194C Histone deacetylase and subunit of Set3 and Rpd3L complexes genetic 1 1 1 Synthetic Growth Defect
HOS4 YIL112W Subunit of the Set3 complex genetic 1 1 1 Synthetic Growth Defect
CCT2 YIL142W Subunit beta of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Negative Genetic
CDC25 YLR310C Membrane bound guanine nucleotide exchange factor genetic 1 1 1 Negative Genetic
NEM1 YHR004C Probable catalytic subunit of Nem1p-Spo7p phosphatase holoenzyme genetic 1 1 1 Negative Genetic
MLP1 YKR095W Myosin-like protein associated with the nuclear envelope physical 1 1 1 Affinity Capture-MS
CRN1 YLR429W Coronin physical 1 1 1 Affinity Capture-MS
CCT7 YJL111W Subunit of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Negative Genetic
LTE1 YAL024C Protein similar to GDP/GTP exchange factors genetic 1 1 1 Synthetic Growth Defect
BCY1 YIL033C Regulatory subunit of the cyclic AMP-dependent protein kinase (PKA) genetic 1 1 1 Negative Genetic
BET5 YML077W Core component of transport protein particle (TRAPP) complexes I-III genetic 1 1 1 Negative Genetic
HSE1 YHL002W Subunit of the endosomal Vps27p-Hse1p complex genetic 1 1 1 Negative Genetic
DRS2 YAL026C Trans-golgi network aminophospholipid translocase (flippase) genetic 1 1 1 Positive Genetic
HEK2 YBL032W RNA binding protein involved in asymmetric localization of ASH1 mRNA physical 1 1 1 Affinity Capture-RNA
DIM1 YPL266W Essential 18S rRNA dimethylase (dimethyladenosine transferase) genetic 1 1 1 Negative Genetic
FAR7 YFR008W Protein involved in recovery from pheromone-induced cell cycle arrest genetic 1 1 1 Negative Genetic
CAF20 YOR276W Phosphoprotein of the mRNA cap-binding complex physical 1 1 1 Affinity Capture-RNA
HIR3 YJR140C Subunit of the HIR complex genetic 1 1 1 Positive Genetic
GSP1 YLR293C Ran GTPase genetic 1 1 1 Negative Genetic
GET1 YGL020C Subunit of the GET complex genetic 1 1 1 Synthetic Growth Defect
GET2 YER083C Subunit of the GET complex genetic 1 1 1 Synthetic Growth Defect
LCP5 YER127W Essential protein involved in maturation of 18S rRNA genetic 1 1 1 Positive Genetic
HSP104 YLL026W Disaggregase physical 1 1 1 Affinity Capture-MS
MTC5 YDR128W Subunit of SEACAT, a subcomplex of the SEA complex genetic 1 1 1 Synthetic Growth Defect
MET30 YIL046W F-box protein containing five copies of the WD40 motif genetic 1 1 1 Negative Genetic
ELM1 YKL048C Serine/threonine protein kinase genetic 1 1 1 Synthetic Growth Defect
CAT5 YOR125C Protein required for ubiquinone (Coenzyme Q) biosynthesis genetic 1 1 1 Negative Genetic
GLE1 YDL207W Cytoplasmic nucleoporin required for polyadenylated mRNA export physical 1 1 1 Affinity Capture-MS
KRI1 YNL308C Essential nucleolar protein required for 40S ribosome biogenesis genetic 1 1 1 Positive Genetic
LAS1 YKR063C Endonuclease involved in pre-rRNA processing at both ends of ITS2 genetic 1 1 1 Negative Genetic
CTF4 YPR135W Chromatin-associated protein genetic 1 1 1 Synthetic Growth Defect
MRE11 YMR224C Nuclease subunit of the MRX complex with Rad50p and Xrs2p genetic 1 1 1 Synthetic Growth Defect
LSM8 YJR022W Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
IST3 YIR005W Component of the U2 snRNP genetic 1 1 1 Positive Genetic
LEM3 YNL323W Membrane protein of the plasma membrane and ER genetic 1 1 1 Negative Genetic
CBP2 YHL038C Required for splicing of the group I intron bI5 of the COB pre-mRNA genetic 1 1 1 Positive Genetic
CLN2 YPL256C G1 cyclin involved in regulation of the cell cycle genetic 1 1 1 Dosage Lethality
FMP48 YGR052W Putative protein of unknown function physical 1 1 1 Affinity Capture-MS
MLP2 YIL149C Myosin-like protein associated with the nuclear envelope physical 1 1 1 Affinity Capture-MS
CTK3 YML112W Gamma subunit of C-terminal domain kinase I genetic 1 1 1 Synthetic Growth Defect
MTQ2 YDR140W S-adenosylmethionine-dependent methyltransferase physical 1 1 1 Affinity Capture-MS
DAD2 YKR083C Essential subunit of the Dam1 complex (aka DASH complex) genetic 1 1 1 Negative Genetic
MCM10 YIL150C Essential chromatin-associated protein genetic 1 1 1 Negative Genetic
IPK1 YDR315C Inositol 1,3,4,5,6-pentakisphosphate 2-kinase genetic 1 1 1 Synthetic Growth Defect
GCN4 YEL009C bZIP transcriptional activator of amino acid biosynthetic genes genetic 1 1 1 Positive Genetic
MAD3 YJL013C Subunit of spindle-assembly checkpoint complex genetic 1 1 1 Negative Genetic
NDC80 YIL144W Component of the kinetochore-associated Ndc80 complex genetic 1 1 1 Negative Genetic
NUF2 YOL069W Component of the kinetochore-associated Ndc80 complex genetic 1 1 1 Negative Genetic
HSP10 YOR020C Mitochondrial matrix co-chaperonin genetic 1 1 1 Negative Genetic
CAK1 YFL029C Cyclin-dependent kinase-activating kinase genetic 1 1 1 Negative Genetic
DLS1 YJL065C Subunit of ISW2/yCHRAC chromatin accessibility complex genetic 1 1 1 Negative Genetic
COG4 YPR105C Essential component of the conserved oligomeric Golgi complex genetic 1 1 1 Negative Genetic
AIM4 YBR194W Protein proposed to be associated with the nuclear pore complex genetic 1 1 1 Synthetic Growth Defect
CEP3 YMR168C Essential kinetochore protein genetic 1 1 1 Negative Genetic
IKI1 YHR187W Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex genetic 1 1 1 Positive Genetic
DOC1 YGL240W Processivity factor genetic 1 1 1 Negative Genetic
NFI1 YOR156C SUMO E3 ligase physical 1 1 1 Affinity Capture-Western
BRE5 YNR051C Ubiquitin protease cofactor genetic 1 1 1 Synthetic Growth Defect
GCR1 YPL075W Transcriptional activator of genes involved in glycolysis genetic 1 1 1 Synthetic Lethality
MCM1 YMR043W Transcription factor genetic 1 1 1 Negative Genetic
BUR6 YER159C Subunit of a heterodimeric NC2 transcription regulator complex genetic 1 1 1 Negative Genetic
GCD10 YNL062C Subunit of tRNA (1-methyladenosine) methyltransferase with Gcd14p genetic 1 1 1 Negative Genetic
MTR2 YKL186C mRNA transport regulator genetic 1 1 1 Negative Genetic
CBF2 YGR140W Essential kinetochore protein genetic 1 1 1 Negative Genetic
MPS2 YGL075C Essential membrane protein localized at nuclear envelope and SPBs genetic 1 1 1 Synthetic Lethality
NMD2 YHR077C Protein involved in the nonsense-mediated mRNA decay (NMD) pathway genetic 1 1 1 Negative Genetic
KAR2 YJL034W ATPase involved in protein import into the ER genetic 1 1 1 Negative Genetic
MOB1 YIL106W Component of the mitotic exit network genetic 1 1 1 Negative Genetic
YRA1 YDR381W Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-MS
SAC3 YDR159W mRNA export factor physical 1 1 1 Affinity Capture-MS
YCK1 YHR135C Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform physical 1 1 1 Affinity Capture-MS
RRP17 YDR412W 5' exoribonuclease required for 5' end processing of pre-60S rRNA physical 1 1 1 Affinity Capture-MS
RRP17 YDR412W 5' exoribonuclease required for 5' end processing of pre-60S rRNA genetic 1 1 1 Positive Genetic
TEF1 YPR080W Translational elongation factor EF-1 alpha physical 1 1 1 Affinity Capture-MS
NUP82 YJL061W Linker nucleoporin component of the nuclear pore complex (NPC) physical 1 1 1 Affinity Capture-MS
NUP42 YDR192C FG-nucleoporin component of central core of the nuclear pore complex physical 1 1 1 Affinity Capture-MS
NUP49 YGL172W FG-nucleoporin component of central core of the nuclear pore complex physical 1 1 1 Affinity Capture-MS
SEH1 YGL100W Subunit of the Nup84 nuclear pore and SEACAT subcomplexes physical 1 1 1 Affinity Capture-MS
SEH1 YGL100W Subunit of the Nup84 nuclear pore and SEACAT subcomplexes genetic 1 1 1 Negative Genetic
POM34 YLR018C Subunit of the transmembrane ring of the nuclear pore complex (NPC) physical 1 1 1 Affinity Capture-MS
SRC1 YML034W Inner nuclear membrane protein physical 1 1 1 Affinity Capture-Western
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes physical 1 1 1 Affinity Capture-Western
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes genetic 1 1 1 Synthetic Growth Defect
RAP1 YNL216W Essential DNA-binding transcription regulator that binds many loci physical 1 1 1 Affinity Capture-Western
RAP1 YNL216W Essential DNA-binding transcription regulator that binds many loci genetic 1 1 1 Positive Genetic
PUF2 YPR042C PUF family mRNA-binding protein physical 1 1 1 Affinity Capture-RNA
PUF4 YGL014W Member of the PUF protein family physical 1 1 1 Affinity Capture-RNA
SEC61 YLR378C Conserved ER protein translocation channel physical 1 1 1 Affinity Capture-MS
UBP15 YMR304W Ubiquitin-specific protease involved in protein deubiquitination physical 1 1 1 Affinity Capture-MS
STU1 YBL034C Microtubule plus-end-tracking non-motor protein genetic 1 1 1 Synthetic Lethality
TSR1 YDL060W Protein required for processing of 20S pre-rRNA in the cytoplasm genetic 1 1 1 Negative Genetic
SYC1 YOR179C Subunit of the APT subcomplex of cleavage and polyadenylation factor genetic 1 1 1 Negative Genetic
SEN15 YMR059W Subunit of the tRNA splicing endonuclease genetic 1 1 1 Negative Genetic
PRP18 YGR006W Splicing factor and component of snRNP U5 genetic 1 1 1 Negative Genetic
TIF1 YKR059W Translation initiation factor eIF4A genetic 1 1 1 Negative Genetic
TUF1 YOR187W Mitochondrial translation elongation factor Tu (EF-Tu) genetic 1 1 1 Negative Genetic
RAD52 YML032C Protein involved in homologous recombination genetic 1 1 1 Negative Genetic
SRP1 YNL189W Karyopherin alpha homolog genetic 1 1 1 Negative Genetic
RLI1 YDR091C Essential Fe-S protein genetic 1 1 1 Positive Genetic
PML1 YLR016C Subunit of the RES complex genetic 1 1 1 Positive Genetic
RKM2 YDR198C Ribosomal protein lysine methyltransferase genetic 1 1 1 Positive Genetic
POP7 YBR167C Subunit of RNase MRP, nuclear RNase P and telomerase genetic 1 1 1 Positive Genetic
SKI6 YGR195W Exosome non-catalytic core component genetic 1 1 1 Positive Genetic
SKY1 YMR216C SR protein kinase (SRPK) genetic 1 1 1 Positive Genetic
SBP1 YHL034C Protein that binds eIF4G and has a role in repression of translation genetic 1 1 1 Positive Genetic
PSG1 YKL077W Protein that promotes the transport and maturation of Pma1 with Exp1 genetic 1 1 1 Positive Genetic
PEX30 YLR324W ER-resident protein involved in peroxisomal biogenesis genetic 1 1 1 Negative Genetic
PER33 YLR064W Protein that localizes to the endoplasmic reticulum genetic 1 1 1 Synthetic Growth Defect
SIC1 YLR079W Cyclin-dependent kinase inhibitor (CKI) genetic 1 1 1 Synthetic Lethality
TTI1 YKL033W Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Negative Genetic
RIF1 YBR275C Protein involved in control of DNA replication genetic 1 1 1 Phenotypic Suppression
PAT1 YCR077C Deadenylation-dependent mRNA-decapping factor genetic 1 1 1 Synthetic Growth Defect
PHO23 YNL097C Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Synthetic Growth Defect
RAD6 YGL058W Ubiquitin-conjugating enzyme (E2) genetic 1 1 1 Synthetic Growth Defect
RPP1A YDL081C Ribosomal stalk protein P1 alpha genetic 1 1 1 Synthetic Growth Defect
RPS21B YJL136C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Synthetic Growth Defect
RTT103 YDR289C Protein involved in transcription termination by RNA polymerase II genetic 1 1 1 Synthetic Growth Defect
RXT2 YBR095C Component of the histone deacetylase Rpd3L complex genetic 1 1 1 Synthetic Growth Defect
SCS7 YMR272C Sphingolipid alpha-hydroxylase genetic 1 1 1 Synthetic Growth Defect
SEC22 YLR268W R-SNARE protein genetic 1 1 1 Synthetic Growth Defect
SET3 YKR029C Defining member of the SET3 histone deacetylase complex genetic 1 1 1 Synthetic Growth Defect
SIF2 YBR103W WD40 repeat-containing subunit of Set3C histone deacetylase complex genetic 1 1 1 Synthetic Growth Defect
SIN3 YOL004W Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 1 1 1 Synthetic Growth Defect
SLA1 YBL007C Cytoskeletal protein binding protein genetic 1 1 1 Synthetic Growth Defect
SNF1 YDR477W AMP-activated S/T protein kinase genetic 1 1 1 Synthetic Growth Defect
SNF4 YGL115W Activating gamma subunit of the AMP-activated Snf1p kinase complex genetic 1 1 1 Synthetic Growth Defect
SNT1 YCR033W Set3C histone deacetylase scaffold genetic 1 1 1 Synthetic Growth Defect
STB5 YHR178W Transcription factor genetic 1 1 1 Synthetic Growth Defect
SUR1 YPL057C Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit genetic 1 1 1 Synthetic Growth Defect
SUS1 YBR111W-A Global transcriptional regulator, component of SAGA, TREX-2 complexes genetic 1 1 1 Synthetic Growth Defect
VPS72 YDR485C Htz1p-binding component of the SWR1 complex genetic 1 1 1 Synthetic Growth Defect
SWC3 YAL011W Protein of unknown function genetic 1 1 1 Synthetic Growth Defect
SWC5 YBR231C Component of the SWR1 complex genetic 1 1 1 Synthetic Growth Defect
VPS71 YML041C Nucleosome-binding component of the SWR1 complex genetic 1 1 1 Synthetic Growth Defect
SWR1 YDR334W Swi2/Snf2-related ATPase genetic 1 1 1 Synthetic Growth Defect
THP1 YOL072W Nuclear pore-associated protein genetic 1 1 1 Synthetic Growth Defect
UBP3 YER151C Ubiquitin-specific protease that cleaves Ub-protein fusions genetic 1 1 1 Synthetic Growth Defect
UBP6 YFR010W Ubiquitin-specific protease genetic 1 1 1 Synthetic Growth Defect
UME1 YPL139C Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 1 1 1 Synthetic Growth Defect
UME6 YDR207C Rpd3L histone deacetylase complex subunit genetic 1 1 1 Synthetic Growth Defect
VIP1 YLR410W Bifunctional inositol pyrophosphate kinase and phosphatase genetic 1 1 1 Synthetic Growth Defect
SPB4 YFL002C Putative ATP-dependent RNA helicase genetic 1 1 1 Positive Genetic
SAD1 YFR005C Conserved zinc-finger domain protein involved in pre-mRNA splicing genetic 1 1 1 Positive Genetic
RPL28 YGL103W Ribosomal 60S subunit protein L28 genetic 1 1 1 Positive Genetic
UTP15 YMR093W Nucleolar protein genetic 1 1 1 Positive Genetic
TOP2 YNL088W Topoisomerase II genetic 1 1 1 Positive Genetic
POL1 YNL102W Catalytic subunit of the DNA polymerase I alpha-primase complex genetic 1 1 1 Positive Genetic
YTM1 YOR272W Ribosomal assembly factor and 66S pre-ribosomal particle constituent genetic 1 1 1 Positive Genetic
SWI1 YPL016W Subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Positive Genetic
POL3 YDL102W Catalytic subunit of DNA polymerase delta genetic 1 1 1 Positive Genetic
TIM22 YDL217C Essential core component of mitochondrial TIM22 complex genetic 1 1 1 Positive Genetic
TAD2 YJL035C Subunit of tRNA-specific adenosine-34 deaminase genetic 1 1 1 Positive Genetic
SED5 YLR026C cis-Golgi t-SNARE syntaxin genetic 1 1 1 Positive Genetic
SMC5 YOL034W Subunit of the SMC5-SMC6 complex genetic 1 1 1 Positive Genetic
XKS1 YGR194C Xylulokinase genetic 1 1 1 Positive Genetic
YCK2 YNL154C Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform genetic 1 1 1 Positive Genetic
SLA2 YNL243W Adaptor protein that links actin to clathrin and endocytosis genetic 1 1 1 Positive Genetic
YPT11 YNL304W Rab GTPase genetic 1 1 1 Positive Genetic
SRB6 YBR253W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
SSS1 YDR086C Subunit of the Sec61p translocation complex (Sec61p-Sss1p-Sbh1p) genetic 1 1 1 Negative Genetic
RRP1 YDR087C Essential evolutionarily conserved nucleolar protein genetic 1 1 1 Negative Genetic
SLU7 YDR088C RNA splicing factor genetic 1 1 1 Negative Genetic
UTP6 YDR449C Nucleolar protein genetic 1 1 1 Negative Genetic
TUB2 YFL037W Beta-tubulin genetic 1 1 1 Negative Genetic
SRM1 YGL097W Nucleotide exchange factor for Gsp1p genetic 1 1 1 Negative Genetic
RPS2 YGL123W Protein component of the small (40S) subunit genetic 1 1 1 Negative Genetic
SEC9 YGR009C t-SNARE protein required for secretory vesicle-plasma membrane fusion genetic 1 1 1 Negative Genetic
YIP1 YGR172C Integral membrane protein genetic 1 1 1 Negative Genetic
TYS1 YGR185C Cytoplasmic tyrosyl-tRNA synthetase genetic 1 1 1 Negative Genetic
YHR020W YHR020W Prolyl-tRNA synthetase genetic 1 1 1 Negative Genetic
RPB3 YIL021W RNA polymerase II third largest subunit B44 genetic 1 1 1 Negative Genetic
THS1 YIL078W Threonyl-tRNA synthetase genetic 1 1 1 Negative Genetic
TAO3 YIL129C Component of the RAM signaling network genetic 1 1 1 Negative Genetic
OST1 YJL002C Alpha subunit of the oligosaccharyltransferase complex of the ER lumen genetic 1 1 1 Negative Genetic
SUI2 YJR007W Alpha subunit of the translation initiation factor eIF2 genetic 1 1 1 Negative Genetic
RFC2 YJR068W Subunit of heteropentameric Replication factor C (RF-C) genetic 1 1 1 Negative Genetic
PRP16 YKR086W DEAH-box RNA helicase genetic 1 1 1 Negative Genetic
SMD2 YLR275W Core Sm protein Sm D2 genetic 1 1 1 Negative Genetic
RPP0 YLR340W Conserved ribosomal protein P0 of the ribosomal stalk genetic 1 1 1 Negative Genetic
TIF34 YMR146C eIF3i subunit of the eukaryotic translation initiation factor 3 (eIF3) genetic 1 1 1 Negative Genetic
RPC19 YNL113W RNA polymerase subunit AC19 genetic 1 1 1 Negative Genetic
RPS3 YNL178W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
POP3 YNL282W Subunit of both RNase MRP and nuclear RNase P genetic 1 1 1 Negative Genetic
RFC1 YOR217W Subunit of heteropentameric Replication factor C (RF-C) genetic 1 1 1 Negative Genetic
SEC63 YOR254C Essential subunit of Sec63 complex genetic 1 1 1 Negative Genetic
RPN8 YOR261C Essential non-ATPase regulatory subunit of the 26S proteasome genetic 1 1 1 Negative Genetic
SEC16 YPL085W COPII vesicle coat protein required for ER transport vesicle budding genetic 1 1 1 Negative Genetic
SUI3 YPL237W Beta subunit of the translation initiation factor eIF2 genetic 1 1 1 Negative Genetic
YTH1 YPR107C Essential RNA-binding component of cleavage and polyadenylation factor genetic 1 1 1 Negative Genetic
RRP15 YPR143W Nucleolar protein genetic 1 1 1 Negative Genetic
SEC23 YPR181C GTPase-activating protein, stimulates the GTPase activity of Sar1p genetic 1 1 1 Negative Genetic
SMX3 YPR182W Core Sm protein Sm F genetic 1 1 1 Negative Genetic
RPN6 YDL097C Essential, non-ATPase regulatory subunit of the 26S proteasome lid genetic 1 1 1 Negative Genetic
RPN5 YDL147W Subunit of the CSN and 26S proteasome lid complexes genetic 1 1 1 Negative Genetic
SLY1 YDR189W Hydrophilic protein involved in ER/Golgi vesicle trafficking genetic 1 1 1 Negative Genetic
SPC19 YDR201W Essential subunit of the Dam1 complex (aka DASH complex) genetic 1 1 1 Negative Genetic
YCG1 YDR325W Subunit of the condensin complex genetic 1 1 1 Negative Genetic
PUP3 YER094C Beta 3 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
RPN11 YFR004W Metalloprotease subunit of 19S regulatory particle genetic 1 1 1 Negative Genetic
SCL1 YGL011C Alpha 1 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
RPT6 YGL048C ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Negative Genetic
NUP192 YJL039C Essential subunit of inner ring of nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
SMC3 YJL074C Subunit of the multiprotein cohesin complex genetic 1 1 1 Negative Genetic
NUP85 YJR042W Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
TAH11 YJR046W DNA replication licensing factor genetic 1 1 1 Negative Genetic
RPT1 YKL145W ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Negative Genetic
PRP19 YLL036C Splicing factor associated with the spliceosome genetic 1 1 1 Negative Genetic
STU2 YLR045C Microtubule polymerase of the XMAP215/Dis1 family genetic 1 1 1 Negative Genetic
SPC24 YMR117C Component of the kinetochore-associated Ndc80 complex genetic 1 1 1 Negative Genetic
RPC34 YNR003C RNA polymerase III subunit C34 genetic 1 1 1 Negative Genetic
PUP1 YOR157C Beta 2 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
SUA7 YPR086W Transcription factor TFIIB genetic 1 1 1 Negative Genetic
PRE2 YPR103W Beta 5 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
RPN7 YPR108W Essential non-ATPase regulatory subunit of the 26S proteasome genetic 1 1 1 Negative Genetic
SGV1 YPR161C Cyclin (Bur2p)-dependent protein kinase genetic 1 1 1 Negative Genetic
SPO7 YAL009W Putative regulatory subunit of Nem1p-Spo7p phosphatase holoenzyme genetic 1 1 1 Negative Genetic
SEI1 YLR404W Seipin involved in lipid droplet (LD) assembly genetic 1 1 1 Negative Genetic
RER1 YCL001W Protein involved in retention of membrane proteins genetic 1 1 1 Negative Genetic
RAM1 YDL090C Beta subunit of the CAAX farnesyltransferase (FTase) genetic 1 1 1 Negative Genetic
RPL4B YDR012W Ribosomal 60S subunit protein L4B genetic 1 1 1 Negative Genetic
VMS1 YDR049W Peptidyl-tRNA hydrolase that releases stalled peptides from ribosomes, genetic 1 1 1 Negative Genetic
SEM1 YDR363W-A 19S proteasome regulatory particle lid subcomplex component genetic 1 1 1 Negative Genetic
YDR391C YDR391C Putative protein of unknown function genetic 1 1 1 Negative Genetic
YND1 YER005W Apyrase with wide substrate specificity genetic 1 1 1 Negative Genetic
YER039C-A YER039C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
SPT2 YER161C Protein involved in negative regulation of transcription genetic 1 1 1 Negative Genetic
TAN1 YGL232W Putative tRNA acetyltransferase genetic 1 1 1 Negative Genetic
PCL5 YHR071W Cyclin genetic 1 1 1 Negative Genetic
SFB3 YHR098C Component of the Sec23p-Sfb3p heterodimer of the COPII vesicle coat genetic 1 1 1 Negative Genetic
THP2 YHR167W Subunit of the THO and TREX complexes genetic 1 1 1 Negative Genetic
YIL014C-A YIL014C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
RPL34B YIL052C Ribosomal 60S subunit protein L34B genetic 1 1 1 Negative Genetic
RPL40A YIL148W Ubiquitin-ribosomal 60S subunit protein L40A fusion protein genetic 1 1 1 Negative Genetic
PRY1 YJL079C Lipid binding protein genetic 1 1 1 Negative Genetic
YJR098C YJR098C Putative protein of unknown function genetic 1 1 1 Negative Genetic
RHO4 YKR055W Non-essential small GTPase genetic 1 1 1 Negative Genetic
UBI4 YLL039C Ubiquitin genetic 1 1 1 Negative Genetic
YLL053C YLL053C Putative protein genetic 1 1 1 Negative Genetic
YLR156C-A YLR156C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
TRM12 YML005W S-adenosylmethionine-dependent methyltransferase genetic 1 1 1 Negative Genetic
PAH1 YMR165C Mg2+-dependent phosphatidate (PA) phosphatase genetic 1 1 1 Negative Genetic
POR1 YNL055C Mitochondrial porin (voltage-dependent anion channel) genetic 1 1 1 Negative Genetic
ZWF1 YNL241C Glucose-6-phosphate dehydrogenase (G6PD) genetic 1 1 1 Negative Genetic
WSC2 YNL283C Sensor-transducer of the stress-activated PKC1-MPK1 signaling pathway genetic 1 1 1 Negative Genetic
VPS27 YNR006W Endosomal protein that forms a complex with Hse1p genetic 1 1 1 Negative Genetic
PLB3 YOL011W Phospholipase B (lysophospholipase) involved in lipid metabolism genetic 1 1 1 Negative Genetic
VPS68 YOL129W Vacuolar membrane protein of unknown function genetic 1 1 1 Negative Genetic
YOR072W-B YOR072W-B Putative protein of unknown function genetic 1 1 1 Negative Genetic
RPS7A YOR096W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
PEX27 YOR193W Peripheral peroxisomal membrane protein genetic 1 1 1 Negative Genetic
PET20 YPL159C Mitochondrial protein genetic 1 1 1 Negative Genetic
SET6 YPL165C SET domain protein of unknown function genetic 1 1 1 Negative Genetic
SKI3 YPR189W Ski complex component and TPR protein genetic 1 1 1 Negative Genetic
PEP4 YPL154C Vacuolar aspartyl protease (proteinase A) genetic 1 1 1 Phenotypic Suppression
MPT5 YGL178W mRNA-binding protein of the PUF family physical 1 1 1 Affinity Capture-RNA
ABF1 YKL112W DNA binding protein with possible chromatin-reorganizing activity genetic 1 1 1 Negative Genetic
FCP1 YMR277W Carboxy-terminal domain (CTD) phosphatase genetic 1 1 1 Negative Genetic
ESC1 YMR219W Protein involved in telomeric silencing physical 1 1 1 Affinity Capture-Western
DOM34 YNL001W Protein that facilitates ribosomal subunit dissociation genetic 1 1 1 Synthetic Growth Defect
ATM1 YMR301C Mitochondrial inner membrane ATP-binding cassette (ABC) transporter genetic 1 1 1 Negative Genetic
BTS1 YPL069C Geranylgeranyl diphosphate synthase (GGPPS) genetic 1 1 1 Negative Genetic
HEH2 YDR458C Inner nuclear membrane (INM) protein physical 1 1 1 Affinity Capture-Western
HEH2 YDR458C Inner nuclear membrane (INM) protein genetic 1 1 1 Synthetic Growth Defect
CFD1 YIL003W Highly conserved iron-sulfur cluster binding protein genetic 1 1 1 Negative Genetic
FAT1 YBR041W Very long chain fatty acyl-CoA synthetase and fatty acid transporter genetic 1 1 1 Synthetic Growth Defect
NGR1 YBR212W RNA binding protein that negatively regulates growth rate genetic 1 1 1 Positive Genetic
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 1 1 1 Negative Genetic
MRPL17 YNL252C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Positive Genetic
BRL1 YHR036W Essential nuclear envelope/ER integral membrane protein genetic 1 1 1 Negative Genetic
ACB1 YGR037C Acyl-CoA-binding protein physical 1 1 1 Affinity Capture-MS
NOP19 YGR251W Ribosome biogenesis factor genetic 1 1 1 Negative Genetic
GCD14 YJL125C Subunit of tRNA (1-methyladenosine) methyltransferase genetic 1 1 1 Negative Genetic
FMP46 YKR049C Putative redox protein containing a thioredoxin fold genetic 1 1 1 Negative Genetic
GLN4 YOR168W Glutamine tRNA synthetase genetic 1 1 1 Negative Genetic
GEM1 YAL048C Outer mitochondrial membrane GTPase, subunit of the ERMES complex genetic 1 1 1 Synthetic Growth Defect
GPI17 YDR434W Transmembrane protein genetic 1 1 1 Positive Genetic
APJ1 YNL077W Hsp40 chaperone with a role in SUMO-mediated protein degradation genetic 1 1 1 Synthetic Growth Defect
DEG1 YFL001W tRNA:pseudouridine synthase genetic 1 1 1 Negative Genetic
DGR2 YKL121W Protein of unknown function genetic 1 1 1 Negative Genetic
HUR1 YGL168W Protein with a role in DNA repair genetic 1 1 1 Synthetic Growth Defect
EOS1 YNL080C Protein involved in N-glycosylation genetic 1 1 1 Negative Genetic
HVG1 YER039C Protein of unknown function genetic 1 1 1 Negative Genetic
NCB2 YDR397C Subunit of a heterodimeric NC2 transcription regulator complex genetic 1 1 1 Negative Genetic
HXT1 YHR094C Low-affinity glucose transporter of the major facilitator superfamily genetic 1 1 1 Negative Genetic
COS1 YNL336W Endosomal protein involved in turnover of plasma membrane proteins genetic 1 1 1 Positive Genetic
LGE1 YPL055C Protein involved in histone H2B ubiquitination genetic 1 1 1 Synthetic Growth Defect
FRM2 YCL026C-A Type II nitroreductase, using NADH as reductant genetic 1 1 1 Negative Genetic
COS7 YDL248W Endosomal protein involved in turnover of plasma membrane proteins genetic 1 1 1 Negative Genetic
GPI13 YLL031C ER membrane localized phosphoryltransferase genetic 1 1 1 Positive Genetic
ERG3 YLR056W C-5 sterol desaturase genetic 1 1 1 Positive Genetic
HTS1 YPR033C Cytoplasmic and mitochondrial histidine tRNA synthetase genetic 1 1 1 Negative Genetic
COX5B YIL111W Subunit Vb of cytochrome c oxidase genetic 1 1 1 Negative Genetic
MAL11 YGR289C High-affinity maltose transporter (alpha-glucoside transporter) genetic 1 1 1 Negative Genetic
MIC27 YNL100W Component of the MICOS complex genetic 1 1 1 Positive Genetic
MSC1 YML128C Protein of unknown function genetic 1 1 1 Negative Genetic
MRM2 YGL136C Mitochondrial 2' O-ribose methyltransferase genetic 1 1 1 Positive Genetic
LDS1 YAL018C Protein Involved in spore wall assembly genetic 1 1 1 Negative Genetic
NAR1 YNL240C Subunit of the cytosolic iron-sulfur (FeS) protein assembly machinery genetic 1 1 1 Positive Genetic
LST4 YKL176C Subunit of the Lst4p-Lst7p GTPase activating protein complex for Gtr2p genetic 1 1 1 Synthetic Growth Defect
ICE2 YIL090W Integral ER membrane protein with type-III transmembrane domains genetic 1 1 1 Negative Genetic
ADF1 YCL058W-A Transcriptional repressor encoded by the FYV5 antisense strand genetic 1 1 1 Negative Genetic