Standard name Systematic name Name description Description
RPL43A YPR043W Ribosomal 60S subunit protein L43A Ribosomal 60S subunit protein L43A; null mutation confers a dominant lethal phenotype; homologous to mammalian ribosomal protein L37A, no bacterial homolog; RPL43A has a paralog, RPL43B, that arose from the whole genome duplication
Visualize the interactome of RPL43A
Links to external databases:
SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 1.0 0.992 1.0

GFP localization & abundance

GFP localization GFP abundance
cytoplasm 44600

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
RPL43A 1 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
RPL43B YJR094W-A Ribosomal 60S subunit protein L43B genetic 4 2 3 Negative Genetic, Synthetic Lethality, Negative Genetic, Negative Genetic
CDC4 YFL009W F-box protein required for both the G1/S and G2/M phase transitions genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
SNF1 YDR477W AMP-activated S/T protein kinase genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
RHO4 YKR055W Non-essential small GTPase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
AVO2 YMR068W Component of a complex containing the Tor2p kinase and other proteins genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
CSF1 YLR087C Protein with structural similarity to lipid transport protein Vps13p genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
RTT103 YDR289C Protein involved in transcription termination by RNA polymerase II genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SPS2 YDR522C Protein expressed during sporulation genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
UBP6 YFR010W Ubiquitin-specific protease genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
YBP2 YGL060W Central kinetochore associated protein genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
TRM2 YKR056W tRNA methyltransferase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
PMP3 YDR276C Small plasma membrane protein genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
RNP1 YLL046C Ribonucleoprotein that contains two RNA recognition motifs (RRM) genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 2 2 2 Synthetic Haploinsufficiency, Negative Genetic
CDC13 YDL220C Single stranded DNA-binding protein found at TG1-3 telomere G-tails genetic 2 2 2 Synthetic Rescue, Positive Genetic
GIS2 YNL255C Translational activator for mRNAs with internal ribosome entry sites physical 2 2 2 Affinity Capture-MS, Affinity Capture-RNA
CDC3 YLR314C Component of the septin ring that is required for cytokinesis genetic 2 1 2 Negative Genetic, Negative Genetic
CEG1 YGL130W Guanylyltransferase involved in mRNA 5' capping genetic 2 1 2 Negative Genetic, Negative Genetic
MYO2 YOR326W Type V myosin motor involved in actin-based transport of cargos genetic 2 1 2 Negative Genetic, Negative Genetic
CAF20 YOR276W Phosphoprotein of the mRNA cap-binding complex physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
PMA1 YGL008C Plasma membrane P2-type H+-ATPase genetic 2 1 2 Negative Genetic, Negative Genetic
ORC3 YLL004W Subunit of the origin recognition complex (ORC) genetic 2 1 2 Negative Genetic, Negative Genetic
SHP1 YBL058W UBX domain-containing substrate adaptor for Cdc48p genetic 2 1 2 Negative Genetic, Negative Genetic
SHS1 YDL225W Component of the septin ring that is required for cytokinesis genetic 2 1 2 Negative Genetic, Negative Genetic
UBC8 YEL012W Ubiquitin-conjugating enzyme that regulates gluconeogenesis genetic 2 1 2 Negative Genetic, Negative Genetic
UFD1 YGR048W Substrate-recruiting cofactor of the Cdc48p-Npl4p-Ufd1p segregase genetic 2 1 2 Negative Genetic, Negative Genetic
TOR2 YKL203C PIK-related protein kinase and rapamycin target genetic 2 1 2 Negative Genetic, Negative Genetic
TRF5 YNL299W Non-canonical poly(A) polymerase genetic 2 1 2 Negative Genetic, Negative Genetic
QCR8 YJL166W Subunit 8 of ubiquinol cytochrome-c reductase (Complex III) genetic 2 1 2 Positive Genetic, Positive Genetic
ERG3 YLR056W C-5 sterol desaturase genetic 2 1 2 Negative Genetic, Negative Genetic
KRE5 YOR336W Protein required for beta-1,6 glucan biosynthesis genetic 2 1 2 Negative Genetic, Negative Genetic
RKR1 YMR247C RING domain E3 ubiquitin ligase physical 2 2 1 Affinity Capture-MS, Affinity Capture-Western
CDC10 YCR002C Component of the septin ring, required for cytokinesis genetic 2 1 1 Negative Genetic, Negative Genetic
PTC1 YDL006W Type 2C protein phosphatase (PP2C) genetic 2 1 1 Negative Genetic, Negative Genetic
PHB1 YGR132C Subunit of the prohibitin complex (Phb1p-Phb2p) genetic 2 1 1 Negative Genetic, Negative Genetic
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p genetic 2 1 1 Negative Genetic, Negative Genetic
VAM7 YGL212W Vacuolar SNARE protein genetic 2 1 1 Negative Genetic, Negative Genetic
SGF73 YGL066W Subunit of DUBm module of SAGA and SLIK genetic 2 1 1 Negative Genetic, Negative Genetic
SIC1 YLR079W Cyclin-dependent kinase inhibitor (CKI) genetic 2 1 1 Negative Genetic, Negative Genetic
TOM70 YNL121C Component of the TOM (translocase of outer membrane) complex genetic 2 1 1 Negative Genetic, Negative Genetic
SOV1 YMR066W Mitochondrial protein of unknown function genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
CYT1 YOR065W Cytochrome c1 genetic 2 1 1 Negative Genetic, Negative Genetic
QCR9 YGR183C Subunit 9 of ubiquinol cytochrome-c reductase (Complex III) genetic 2 1 1 Negative Genetic, Negative Genetic
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
SPT10 YJL127C Histone H3 acetylase with a role in transcriptional regulation regulation 1 1 1 DNA to cDNA expression microarray evidence
FKH2 YNL068C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
GCR1 YPL075W Transcriptional activator of genes involved in glycolysis regulation 1 1 1 DNA to cDNA expression microarray evidence
XBP1 YIL101C Transcriptional repressor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RAP1 YNL216W Essential DNA-binding transcription regulator that binds many loci regulation 1 1 1 DNA to cDNA expression microarray evidence
STP1 YDR463W Transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAP6 YDR259C Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SIN4 YNL236W Subunit of the RNA polymerase II mediator complex regulation 1 1 1 DNA to cDNA expression microarray evidence
HSF1 YGL073W Trimeric heat shock transcription factor regulation 1 1 1 DNA to cDNA expression microarray evidence
REB1 YBR049C RNA polymerase I enhancer binding protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CST6 YIL036W Basic leucine zipper (bZIP) transcription factor from ATF/CREB family regulation 1 1 1 DNA to cDNA expression microarray evidence
HMS1 YOR032C bHLH protein with similarity to myc-family transcription factors regulation 1 1 1 DNA to cDNA expression microarray evidence
IFH1 YLR223C Coactivator, regulates transcription of ribosomal protein (RP) genes regulation 1 1 1 chromatin immunoprecipitation-seq evidence
PIP2 YOR363C Autoregulatory, oleate-activated transcription factor regulation 1 1 1 DNA to cDNA expression microarray evidence
CBF5 YLR175W Pseudouridine synthase catalytic subunit of box H/ACA snoRNPs genetic 1 1 1 Negative Genetic
RPB3 YIL021W RNA polymerase II third largest subunit B44 physical 1 1 1 Affinity Capture-MS
ENP2 YGR145W Component of the SSU genetic 1 1 1 Negative Genetic
EAF1 YDR359C Component of the NuA4 histone acetyltransferase complex genetic 1 1 1 Positive Genetic
BRX1 YOL077C Nucleolar protein genetic 1 1 1 Negative Genetic
RPF1 YHR088W Protein involved in assembly and export of the large ribosomal subunit physical 1 1 1 Co-purification
RPL16A YIL133C Ribosomal 60S subunit protein L16A physical 1 1 1 Affinity Capture-MS
RMP1 YLR145W Subunit of RNase MRP physical 1 1 1 Affinity Capture-RNA
BRR2 YER172C RNA-dependent ATPase RNA helicase (DEIH box) genetic 1 1 1 Negative Genetic
NUG1 YER006W GTPase that associates with nuclear 60S pre-ribosomes physical 1 1 1 Affinity Capture-MS
MRT4 YKL009W Protein involved in mRNA turnover and ribosome assembly genetic 1 1 1 Negative Genetic
NOP58 YOR310C Protein involved in producing mature rRNAs and snoRNAs genetic 1 1 1 Negative Genetic
LSM1 YJL124C Lsm (Like Sm) protein genetic 1 1 1 Positive Genetic
CSL4 YNL232W Exosome non-catalytic core component genetic 1 1 1 Negative Genetic
RPB5 YBR154C RNA polymerase subunit ABC27 genetic 1 1 1 Negative Genetic
NAP1 YKR048C Histone chaperone and assembly chaperone for Rps6a/b genetic 1 1 1 Negative Genetic
GCD2 YGR083C Delta subunit of the translation initiation factor eIF2B genetic 1 1 1 Negative Genetic
PRE10 YOR362C Alpha 7 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
AAR2 YBL074C Component of the U5 snRNP complex genetic 1 1 1 Negative Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex genetic 1 1 1 Synthetic Rescue
ECM16 YMR128W Essential DEAH-box ATP-dependent RNA helicase specific to U3 snoRNP physical 1 1 1 Affinity Capture-MS
LSG1 YGL099W Putative GTPase involved in 60S ribosomal subunit biogenesis physical 1 1 1 Affinity Capture-MS
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
HGH1 YGR187C Chaperone protein for translation factor eEF2 physical 1 1 1 Affinity Capture-MS
APC1 YNL172W Largest subunit of the Anaphase-Promoting Complex/Cyclosome genetic 1 1 1 Positive Genetic
APL6 YGR261C Beta3-like subunit of the yeast AP-3 complex genetic 1 1 1 Negative Genetic
ASC1 YMR116C G-protein beta subunit and guanine dissociation inhibitor for Gpa2p physical 1 1 1 Affinity Capture-MS
BEM2 YER155C Rho GTPase activating protein (RhoGAP) genetic 1 1 1 Negative Genetic
CDC24 YAL041W Guanine nucleotide exchange factor (GEF) for Cdc42p genetic 1 1 1 Negative Genetic
NOG2 YNR053C Putative GTPase physical 1 1 1 Affinity Capture-MS
AVO1 YOL078W Component of the membrane-bound TORC2 complex genetic 1 1 1 Negative Genetic
COP1 YDL145C Alpha subunit of COPI vesicle coatomer complex genetic 1 1 1 Positive Genetic
CDC16 YKL022C Subunit of the anaphase-promoting complex/cyclosome (APC/C) genetic 1 1 1 Negative Genetic
CCT4 YDL143W Subunit of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Dosage Rescue
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
ECM29 YHL030W Scaffold protein physical 1 1 1 Affinity Capture-MS
HSL1 YKL101W Nim1p-related protein kinase genetic 1 1 1 Negative Genetic
KRR1 YCL059C Nucleolar protein required for rRNA synthesis and ribosomal assembly genetic 1 1 1 Negative Genetic
END3 YNL084C EH domain-containing protein involved in endocytosis genetic 1 1 1 Negative Genetic
LAS17 YOR181W Actin assembly factor genetic 1 1 1 Negative Genetic
COG3 YER157W Essential component of the conserved oligomeric Golgi complex genetic 1 1 1 Negative Genetic
IMG1 YCR046C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
MTR10 YOR160W Nuclear import receptor genetic 1 1 1 Positive Genetic
CMD1 YBR109C Calmodulin genetic 1 1 1 Negative Genetic
ARP8 YOR141C Nuclear actin-related protein involved in chromatin remodeling genetic 1 1 1 Negative Genetic
NMD3 YHR170W Protein involved in nuclear export of the large ribosomal subunit genetic 1 1 1 Negative Genetic
FAS2 YPL231W Alpha subunit of fatty acid synthetase genetic 1 1 1 Negative Genetic
NUP116 YMR047C FG-nucleoporin component of central core of the nuclear pore complex genetic 1 1 1 Negative Genetic
ORC1 YML065W Largest subunit of the origin recognition complex physical 1 1 1 Affinity Capture-MS
GIM3 YNL153C Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Positive Genetic
DOA4 YDR069C Ubiquitin hydrolase genetic 1 1 1 Negative Genetic
POL1 YNL102W Catalytic subunit of the DNA polymerase I alpha-primase complex genetic 1 1 1 Negative Genetic
POL12 YBL035C B subunit of DNA polymerase alpha-primase complex genetic 1 1 1 Negative Genetic
HSP82 YPL240C Hsp90 chaperone physical 1 1 1 Affinity Capture-MS
EST3 YIL009C-A Component of the telomerase holoenzyme genetic 1 1 1 Negative Genetic
PRP21 YJL203W Subunit of the SF3a splicing factor complex genetic 1 1 1 Negative Genetic
POL2 YNL262W Catalytic subunit of DNA polymerase (II) epsilon genetic 1 1 1 Negative Genetic
NOC4 YPR144C Nucleolar protein physical 1 1 1 Affinity Capture-MS
RAM1 YDL090C Beta subunit of the CAAX farnesyltransferase (FTase) genetic 1 1 1 Negative Genetic
RET2 YFR051C Delta subunit of the coatomer complex (COPI) genetic 1 1 1 Positive Genetic
RFA3 YJL173C Subunit of heterotrimeric Replication Protein A (RPA) genetic 1 1 1 Positive Genetic
MRPL6 YHR147C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
RPB10 YOR210W RNA polymerase subunit ABC10-beta genetic 1 1 1 Negative Genetic
DBP2 YNL112W ATP-dependent RNA helicase of the DEAD-box protein family genetic 1 1 1 Negative Genetic
RPL2A YFR031C-A Ribosomal 60S subunit protein L2A physical 1 1 1 Affinity Capture-MS
MAF1 YDR005C Highly conserved negative regulator of RNA polymerase III genetic 1 1 1 Synthetic Growth Defect
CSE1 YGL238W Nuclear envelope protein that acts as a recycling factor genetic 1 1 1 Negative Genetic
CCT2 YIL142W Subunit beta of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Dosage Rescue
CDC25 YLR310C Membrane bound guanine nucleotide exchange factor genetic 1 1 1 Negative Genetic
IST2 YBR086C Cortical ER protein involved in ER-plasma membrane (PM) tethering genetic 1 1 1 Positive Genetic
HEM13 YDR044W Coproporphyrinogen III oxidase genetic 1 1 1 Negative Genetic
CCT6 YDR188W Subunit of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Dosage Rescue
CCT7 YJL111W Subunit of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Positive Genetic
HEK2 YBL032W RNA binding protein involved in asymmetric localization of ASH1 mRNA physical 1 1 1 Affinity Capture-RNA
PUF3 YLL013C Protein of the mitochondrial outer surface physical 1 1 1 Affinity Capture-RNA
AIM41 YOR215C Protein of unknown function genetic 1 1 1 Negative Genetic
GAS1 YMR307W Beta-1,3-glucanosyltransferase required for cell wall assembly genetic 1 1 1 Negative Genetic
ATG31 YDR022C Autophagy-specific protein required for autophagosome formation genetic 1 1 1 Negative Genetic
POR1 YNL055C Mitochondrial porin (voltage-dependent anion channel) genetic 1 1 1 Positive Genetic
COF1 YLL050C Cofilin, involved in pH-dependent actin filament depolarization genetic 1 1 1 Negative Genetic
GPD2 YOL059W NAD-dependent glycerol 3-phosphate dehydrogenase genetic 1 1 1 Negative Genetic
PET9 YBL030C Major ADP/ATP carrier of the mitochondrial inner membrane genetic 1 1 1 Dosage Rescue
PBR1 YNL181W Putative oxidoreductase genetic 1 1 1 Negative Genetic
CBK1 YNL161W Serine/threonine protein kinase of the the RAM signaling network genetic 1 1 1 Negative Genetic
FUM1 YPL262W Fumarase genetic 1 1 1 Negative Genetic
MET30 YIL046W F-box protein containing five copies of the WD40 motif genetic 1 1 1 Negative Genetic
HSL7 YBR133C Protein arginine N-methyltransferase genetic 1 1 1 Negative Genetic
CDC60 YPL160W Cytosolic leucyl tRNA synthetase genetic 1 1 1 Positive Genetic
ADH4 YGL256W Alcohol dehydrogenase isoenzyme type IV genetic 1 1 1 Negative Genetic
POL30 YBR088C Proliferating cell nuclear antigen (PCNA) genetic 1 1 1 Negative Genetic
CDC37 YDR168W Essential Hsp90p co-chaperone genetic 1 1 1 Negative Genetic
MAK11 YKL021C Protein involved in an early step of 60S ribosomal subunit biogenesis genetic 1 1 1 Negative Genetic
PRM2 YIL037C Pheromone-regulated protein genetic 1 1 1 Negative Genetic
NTF2 YER009W Nuclear envelope protein genetic 1 1 1 Negative Genetic
FRS2 YFL022C Alpha subunit of cytoplasmic phenylalanyl-tRNA synthetase genetic 1 1 1 Negative Genetic
DNL4 YOR005C DNA ligase required for nonhomologous end-joining (NHEJ) genetic 1 1 1 Negative Genetic
AIM46 YHR199C Protein of unknown function genetic 1 1 1 Negative Genetic
KSP1 YHR082C Serine/threonine protein kinase genetic 1 1 1 Negative Genetic
LHS1 YKL073W Molecular chaperone of the endoplasmic reticulum lumen genetic 1 1 1 Negative Genetic
NUS1 YDL193W Forms dehydrodolichyl diphosphate synthase complex with RER2 or SRT1 genetic 1 1 1 Negative Genetic
ARF2 YDL137W ADP-ribosylation factor genetic 1 1 1 Negative Genetic
NOP53 YPL146C Nucleolar protein physical 1 1 1 Co-purification
EAP1 YKL204W eIF4E-associated protein, competes with eIF4G for binding to eIF4E physical 1 1 1 Affinity Capture-MS
MIG1 YGL035C Transcription factor involved in glucose repression genetic 1 1 1 Negative Genetic
PMI40 YER003C Mannose-6-phosphate isomerase genetic 1 1 1 Negative Genetic
PRS5 YOL061W 5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase genetic 1 1 1 Negative Genetic
RNR3 YIL066C Minor isoform of large subunit of ribonucleotide-diphosphate reductase genetic 1 1 1 Negative Genetic
MMS22 YLR320W Subunit of E3 ubiquitin ligase complex involved in replication repair physical 1 1 1 Affinity Capture-MS
KKQ8 YKL168C Putative serine/threonine protein kinase with unknown cellular role genetic 1 1 1 Negative Genetic
ADH5 YBR145W Alcohol dehydrogenase isoenzyme V genetic 1 1 1 Negative Genetic
ARH1 YDR376W Oxidoreductase of the mitochondrial inner membrane genetic 1 1 1 Negative Genetic
ISC10 YER180C Meiosis-specific MAPK inhibitor genetic 1 1 1 Positive Genetic
MOB2 YFL034C-B Activator of Cbk1p kinase genetic 1 1 1 Positive Genetic
MPD2 YOL088C Member of the protein disulfide isomerase (PDI) family genetic 1 1 1 Negative Genetic
NDL1 YLR254C Homolog of nuclear distribution factor NudE genetic 1 1 1 Positive Genetic
PEX21 YGR239C Peroxin required for peroxisomal matrix protein targeting genetic 1 1 1 Negative Genetic
KEG1 YFR042W Integral membrane protein of the ER genetic 1 1 1 Negative Genetic
APC5 YOR249C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Positive Genetic
COG7 YGL005C Component of the conserved oligomeric Golgi complex genetic 1 1 1 Negative Genetic
COG6 YNL041C Component of the conserved oligomeric Golgi complex genetic 1 1 1 Positive Genetic
COG5 YNL051W Component of the conserved oligomeric Golgi complex genetic 1 1 1 Positive Genetic
IPL1 YPL209C Aurora kinase of chromosomal passenger complex genetic 1 1 1 Positive Genetic
BRE5 YNR051C Ubiquitin protease cofactor physical 1 1 1 Affinity Capture-MS
PHO4 YFR034C Basic helix-loop-helix (bHLH) transcription factor of the myc-family physical 1 1 1 Affinity Capture-MS
BFR1 YOR198C Component of mRNP complexes associated with polyribosomes physical 1 1 1 Affinity Capture-RNA
DBF4 YDR052C Regulatory subunit of Cdc7p-Dbf4p kinase complex genetic 1 1 1 Negative Genetic
CBF2 YGR140W Essential kinetochore protein genetic 1 1 1 Negative Genetic
PAN1 YIR006C Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p genetic 1 1 1 Negative Genetic
PAM18 YLR008C Subunit of the import motor (PAM complex) genetic 1 1 1 Negative Genetic
MGM1 YOR211C Mitochondrial GTPase, present in complex with Ugo1p and Fzo1p genetic 1 1 1 Positive Genetic
PEP8 YJL053W Vacuolar protein component of the retromer genetic 1 1 1 Positive Genetic
ATG2 YNL242W Peripheral membrane protein required for autophagic vesicle formation genetic 1 1 1 Negative Genetic
MPT5 YGL178W mRNA-binding protein of the PUF family genetic 1 1 1 Synthetic Rescue
FCP1 YMR277W Carboxy-terminal domain (CTD) phosphatase genetic 1 1 1 Negative Genetic
MCM7 YBR202W Component of the Mcm2-7 hexameric helicase complex genetic 1 1 1 Positive Genetic
ESC2 YDR363W Sumo-like domain protein genetic 1 1 1 Negative Genetic
INP53 YOR109W Polyphosphatidylinositol phosphatase genetic 1 1 1 Negative Genetic
HKR1 YDR420W Mucin family member that functions as an osmosensor in the HOG pathway genetic 1 1 1 Negative Genetic
GIC2 YDR309C Rho-family GTPase interacting protein and Cdc42p effector genetic 1 1 1 Negative Genetic
PRP22 YER013W DEAH-box RNA-dependent ATPase/ATP-dependent RNA helicase genetic 1 1 1 Negative Genetic
MIX17 YMR002W Mitochondrial intermembrane space protein genetic 1 1 1 Negative Genetic
RPL25 YOL127W Ribosomal 60S subunit protein L25 physical 1 1 1 Affinity Capture-MS
RPL31A YDL075W Ribosomal 60S subunit protein L31A physical 1 1 1 Affinity Capture-MS
MNN11 YJL183W Subunit of a Golgi mannosyltransferase complex genetic 1 1 1 Positive Genetic
NUP188 YML103C Subunit of the inner ring of the nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
DOM34 YNL001W Protein that facilitates ribosomal subunit dissociation genetic 1 1 1 Dosage Rescue
FAF1 YIL019W Protein required for pre-rRNA processing genetic 1 1 1 Negative Genetic
EAF7 YNL136W Subunit of the NuA4 histone acetyltransferase complex genetic 1 1 1 Negative Genetic
INN1 YNL152W Essential protein that associates with contractile actomyosin ring genetic 1 1 1 Negative Genetic
CNN1 YFR046C Kinetochore protein genetic 1 1 1 Negative Genetic
CUE4 YML101C Protein of unknown function genetic 1 1 1 Negative Genetic
PSG1 YKL077W Protein that promotes the transport and maturation of Pma1 with Exp1 physical 1 1 1 Affinity Capture-MS
PYK2 YOR347C Pyruvate kinase genetic 1 1 1 Negative Genetic
DRN1 YGR093W Splicing factor that modulates turnover of branched RNAs by Dbr1p physical 1 1 1 Affinity Capture-RNA
PBP4 YDL053C Pbp1p binding protein genetic 1 1 1 Negative Genetic
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family physical 1 1 1 Affinity Capture-MS
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 1 1 1 Negative Genetic
PMT5 YDL093W Protein O-mannosyltransferase genetic 1 1 1 Negative Genetic
EKI1 YDR147W Ethanolamine kinase genetic 1 1 1 Negative Genetic
MSS4 YDR208W Phosphatidylinositol-4-phosphate 5-kinase genetic 1 1 1 Negative Genetic
MRPL17 YNL252C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
ADE16 YLR028C Enzyme of 'de novo' purine biosynthesis genetic 1 1 1 Negative Genetic
BRL1 YHR036W Essential nuclear envelope/ER integral membrane protein genetic 1 1 1 Negative Genetic
NEL1 YHR035W Activator of Sar1p GTPase activity genetic 1 1 1 Negative Genetic
NOP19 YGR251W Ribosome biogenesis factor genetic 1 1 1 Positive Genetic
NDT80 YHR124W Meiosis-specific transcription factor genetic 1 1 1 Negative Genetic
ELF1 YKL160W Transcription elongation factor with a conserved zinc finger domain genetic 1 1 1 Negative Genetic
COQ6 YGR255C Flavin-dependent monooxygenase involved in ubiquinone biosynthesis genetic 1 1 1 Negative Genetic
IRC25 YLR021W Component of a heterodimeric Poc4p-Irc25p chaperone genetic 1 1 1 Negative Genetic
AIM23 YJL131C Mitochondrial translation initiation factor 3 (IF3, mIF3) genetic 1 1 1 Positive Genetic
RPL19A YBR084C-A Ribosomal 60S subunit protein L19A physical 1 1 1 Affinity Capture-MS
SEC31 YDL195W Component of the Sec13p-Sec31p complex of the COPII vesicle coat physical 1 1 1 Affinity Capture-MS
RTT102 YGR275W Component of both the SWI/SNF and RSC chromatin remodeling complexes physical 1 1 1 Affinity Capture-MS
RPN10 YHR200W Proteasome polyubiquitin receptor physical 1 1 1 Affinity Capture-MS
UBP3 YER151C Ubiquitin-specific protease that cleaves Ub-protein fusions physical 1 1 1 Affinity Capture-MS
SLF1 YDR515W RNA binding protein that associates with polysomes physical 1 1 1 Affinity Capture-RNA
SRO9 YCL037C Cytoplasmic RNA-binding protein physical 1 1 1 Affinity Capture-RNA
RQC1 YDR333C Component of the ribosome quality control complex (RQC) physical 1 1 1 Affinity Capture-MS
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p physical 1 1 1 Affinity Capture-MS
TOM1 YDR457W E3 ubiquitin ligase of the hect-domain class physical 1 1 1 Affinity Capture-MS
RVB2 YPL235W ATP-dependent DNA helicase, also known as reptin physical 1 1 1 Affinity Capture-MS
RVB1 YDR190C ATP-dependent DNA helicase, also known as pontin physical 1 1 1 Affinity Capture-MS
TMA108 YIL137C Ribosome-associated, nascent chain binding factor physical 1 1 1 Affinity Capture-MS
SCP160 YJL080C Essential RNA-binding G protein effector of mating response pathway physical 1 1 1 Affinity Capture-MS
TMA46 YOR091W Protein of unknown function that associates with translating ribosomes physical 1 1 1 Affinity Capture-MS
RTT105 YER104W Chaperone for Replication Protein A complex (RPA) physical 1 1 1 Affinity Capture-MS
RPS0A YGR214W Ribosomal 40S subunit protein S0A physical 1 1 1 Affinity Capture-MS
RPS1A YLR441C Ribosomal protein of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPS2 YGL123W Protein component of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPS6A YPL090C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS7A YOR096W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS8A YBL072C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS9A YPL081W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS10A YOR293W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS12 YOR369C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS13 YDR064W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS15 YOL040C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS17A YML024W Ribosomal protein 51 (rp51) of the small (40s) subunit physical 1 1 1 Affinity Capture-MS
RPS18A YDR450W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS19A YOL121C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS20 YHL015W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS27A YKL156W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS3 YNL178W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS14A YCR031C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RTT109 YLL002W Histone acetyltransferase genetic 1 1 1 Synthetic Growth Defect
TCP1 YDR212W Alpha subunit of chaperonin-containing T-complex genetic 1 1 1 Dosage Rescue
TAE1 YBR261C AdoMet-dependent proline methyltransferase genetic 1 1 1 Synthetic Growth Defect
TAF1 YGR274C TFIID subunit, involved in RNA pol II transcription initiation genetic 1 1 1 Synthetic Lethality
TTI1 YKL033W Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Positive Genetic
TEL2 YGR099W Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Positive Genetic
SLX4 YLR135W Endonuclease involved in processing DNA genetic 1 1 1 Positive Genetic
YDR341C YDR341C Arginyl-tRNA synthetase genetic 1 1 1 Positive Genetic
ZWF1 YNL241C Glucose-6-phosphate dehydrogenase (G6PD) genetic 1 1 1 Positive Genetic
TOF1 YNL273W Subunit of a replication-pausing checkpoint complex genetic 1 1 1 Positive Genetic
SEC26 YDR238C Essential beta-coat protein of the COPI coatomer genetic 1 1 1 Negative Genetic
YRA1 YDR381W Nuclear polyadenylated RNA-binding protein genetic 1 1 1 Negative Genetic
SPP41 YDR464W Protein of unknown function genetic 1 1 1 Negative Genetic
TRS31 YDR472W Core component of transport protein particle (TRAPP) complexes I-III genetic 1 1 1 Negative Genetic
UTR5 YEL035C Protein of unknown function genetic 1 1 1 Negative Genetic
RPN11 YFR004W Metalloprotease subunit of 19S regulatory particle genetic 1 1 1 Negative Genetic
RSC8 YFR037C Component of the RSC chromatin remodeling complex genetic 1 1 1 Negative Genetic
SUA5 YGL169W Protein involved in threonylcarbamoyl adenosine biosynthesis genetic 1 1 1 Negative Genetic
SEC9 YGR009C t-SNARE protein required for secretory vesicle-plasma membrane fusion genetic 1 1 1 Negative Genetic
VHT1 YGR065C High-affinity plasma membrane H+-biotin (vitamin H) symporter genetic 1 1 1 Negative Genetic
YIP1 YGR172C Integral membrane protein genetic 1 1 1 Negative Genetic
TYS1 YGR185C Cytoplasmic tyrosyl-tRNA synthetase genetic 1 1 1 Negative Genetic
YPP1 YGR198W Cargo-transport protein involved in endocytosis genetic 1 1 1 Negative Genetic
SEC6 YIL068C Essential 88kDa subunit of the exocyst complex genetic 1 1 1 Negative Genetic
UTP18 YJL069C Small-subunit processome protein involved in pre-18S rRNA maturation genetic 1 1 1 Negative Genetic
URA6 YKL024C Uridylate kinase genetic 1 1 1 Negative Genetic
RPT1 YKL145W ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Negative Genetic
SRP102 YKL154W Signal recognition particle (SRP) receptor beta subunit genetic 1 1 1 Negative Genetic
RRN5 YLR141W Protein involved in transcription of rDNA by RNA polymerase I genetic 1 1 1 Negative Genetic
TRS130 YMR218C Component of transport protein particle (TRAPP) complex II genetic 1 1 1 Negative Genetic
SRV2 YNL138W CAP (cyclase-associated protein) genetic 1 1 1 Negative Genetic
SEC2 YNL272C Guanyl-nucleotide exchange factor for the small G-protein Sec4p genetic 1 1 1 Negative Genetic
RPN8 YOR261C Essential non-ATPase regulatory subunit of the 26S proteasome genetic 1 1 1 Negative Genetic
SLA1 YBL007C Cytoskeletal protein binding protein genetic 1 1 1 Negative Genetic
RPL4A YBR031W Ribosomal 60S subunit protein L4A genetic 1 1 1 Negative Genetic
SCO1 YBR037C Copper-binding protein of mitochondrial inner membrane genetic 1 1 1 Negative Genetic
TSC3 YBR058C-A Protein that stimulates the activity of serine palmitoyltransferase genetic 1 1 1 Negative Genetic
YBR298C-A YBR298C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
SNT1 YCR033W Set3C histone deacetylase scaffold genetic 1 1 1 Negative Genetic
SAC6 YDR129C Fimbrin, actin-bundling protein genetic 1 1 1 Negative Genetic
RSM24 YDR175C Mitochondrial ribosomal protein of the small subunit genetic 1 1 1 Negative Genetic
RVS167 YDR388W Calmodulin-binding actin-associated protein genetic 1 1 1 Negative Genetic
YAT2 YER024W Carnitine acetyltransferase genetic 1 1 1 Negative Genetic
YFH7 YFR007W Putative kinase with similarity to the PRK/URK/PANK kinase subfamily genetic 1 1 1 Negative Genetic
SDS23 YGL056C Protein involved in cell separation during budding genetic 1 1 1 Negative Genetic
SNF4 YGL115W Activating gamma subunit of the AMP-activated Snf1p kinase complex genetic 1 1 1 Negative Genetic
YGL159W YGL159W Putative protein of unknown function genetic 1 1 1 Negative Genetic
YGR111W YGR111W Putative protein of unknown function genetic 1 1 1 Negative Genetic
YGR153W YGR153W Putative protein of unknown function genetic 1 1 1 Negative Genetic
TRS65 YGR166W Component of transport protein particle (TRAPP) complex II genetic 1 1 1 Negative Genetic
SOL4 YGR248W 6-phosphogluconolactonase genetic 1 1 1 Negative Genetic
YGR273C YGR273C Putative protein of unknown function genetic 1 1 1 Negative Genetic
SPO11 YHL022C Meiosis-specific protein required for meiotic recombination genetic 1 1 1 Negative Genetic
YIL014C-A YIL014C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
SSM4 YIL030C Membrane-embedded ubiquitin-protein ligase and retrotranslocase genetic 1 1 1 Negative Genetic
YJL107C YJL107C Putative protein of unknown function genetic 1 1 1 Negative Genetic
VMA5 YKL080W Subunit C of the V1 peripheral membrane domain of V-ATPase genetic 1 1 1 Negative Genetic
YLR031W YLR031W Putative protein of unknown function genetic 1 1 1 Negative Genetic
UBC12 YLR306W Enzyme that mediates the conjugation of Rub1p genetic 1 1 1 Negative Genetic
YLR345W YLR345W Similar to 6-phosphofructo-2-kinase enzymes genetic 1 1 1 Negative Genetic
YPT7 YML001W Rab family GTPase genetic 1 1 1 Negative Genetic
SUB1 YMR039C Transcriptional regulator genetic 1 1 1 Negative Genetic
TPM1 YNL079C Major isoform of tropomyosin genetic 1 1 1 Negative Genetic
SWS2 YNL081C Putative mitochondrial ribosomal protein of the small subunit genetic 1 1 1 Negative Genetic
SLA2 YNL243W Adaptor protein that links actin to clathrin and endocytosis genetic 1 1 1 Negative Genetic
YNL320W YNL320W Putative protein of unknown function genetic 1 1 1 Negative Genetic
RSM19 YNR037C Mitochondrial ribosomal protein of the small subunit genetic 1 1 1 Negative Genetic
SHE4 YOR035C Protein containing a UCS (UNC-45/CRO1/SHE4) domain genetic 1 1 1 Negative Genetic
WHI2 YOR043W Negative regulator of TORC1 in response to limiting leucine genetic 1 1 1 Negative Genetic
YVC1 YOR087W Vacuolar cation channel genetic 1 1 1 Negative Genetic
VPS21 YOR089C Endosomal Rab family GTPase genetic 1 1 1 Negative Genetic
YOR296W YOR296W Putative protein of unknown function genetic 1 1 1 Negative Genetic
YOR381W-A YOR381W-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
YNG2 YHR090C Subunit of NuA4, an essential histone acetyltransferase complex genetic 1 1 1 Negative Genetic
USO1 YDL058W Essential protein involved in vesicle-mediated ER to Golgi transport genetic 1 1 1 Positive Genetic
VPS35 YJL154C Endosomal subunit of membrane-associated retromer complex genetic 1 1 1 Positive Genetic
VPS38 YLR360W Part of a Vps34p phosphatidylinositol 3-kinase complex genetic 1 1 1 Negative Genetic
YDR169C-A YDR169C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
SUM1 YDR310C Transcriptional repressor that regulates middle-sporulation genes genetic 1 1 1 Negative Genetic
SET1 YHR119W Histone methyltransferase, subunit of the COMPASS (Set1C) complex genetic 1 1 1 Negative Genetic
UBP8 YMR223W Ubiquitin-specific protease component of the SAGA acetylation complex genetic 1 1 1 Negative Genetic
SPO23 YBR250W Protein of unknown function genetic 1 1 1 Negative Genetic
TUB4 YLR212C Gamma-tubulin genetic 1 1 1 Synthetic Rescue
YTA6 YPL074W Putative ATPase of the CDC48/PAS1/SEC18 (AAA) family genetic 1 1 1 Synthetic Growth Defect
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 1 1 1 Negative Genetic
RPL26A YLR344W Ribosomal 60S subunit protein L26A physical 1 1 1 Affinity Capture-MS
EMA35 YCR100C Protein involved in protein sorting genetic 1 1 1 Negative Genetic
PHO91 YNR013C Low-affinity vacuolar phosphate transporter genetic 1 1 1 Negative Genetic
NMT1 YLR195C N-myristoyl transferase genetic 1 1 1 Negative Genetic
ERG24 YNL280C C-14 sterol reductase genetic 1 1 1 Negative Genetic
EOS1 YNL080C Protein involved in N-glycosylation genetic 1 1 1 Negative Genetic
GPI19 YDR437W Subunit of GPI-GlcNAc transferase involved in synthesis of GlcNAc-PI genetic 1 1 1 Positive Genetic
DNF2 YDR093W Aminophospholipid translocase (flippase) genetic 1 1 1 Negative Genetic
CDC50 YCR094W Endosomal protein that interacts with phospholipid flippase Drs2p genetic 1 1 1 Negative Genetic
GIS1 YDR096W Histone demethylase and transcription factor genetic 1 1 1 Negative Genetic
PSR2 YLR019W Putative plasma membrane phosphatase genetic 1 1 1 Negative Genetic
MPS3 YJL019W Nuclear envelope protein genetic 1 1 1 Synthetic Rescue
ERG4 YGL012W C-24(28) sterol reductase genetic 1 1 1 Negative Genetic
EFG1 YGR271C-A Ribosome biogenesis factor required for maturation of 18S rRNA physical 1 1 1 Affinity Capture-MS
GPI13 YLL031C ER membrane localized phosphoryltransferase genetic 1 1 1 Negative Genetic
MEP2 YNL142W Ammonium permease involved in regulation of pseudohyphal growth genetic 1 1 1 Negative Genetic
CDS1 YBR029C Phosphatidate cytidylyltransferase (CDP-diglyceride synthetase) genetic 1 1 1 Negative Genetic
GPC1 YGR149W Glycerophosphocholine acyltransferase (GPCAT) genetic 1 1 1 Negative Genetic
GRX2 YDR513W Cytoplasmic glutaredoxin genetic 1 1 1 Negative Genetic
CRS5 YOR031W Copper-binding metallothionein genetic 1 1 1 Negative Genetic
GRE2 YOL151W 3-methylbutanal reductase and NADPH-dependent methylglyoxal reductase genetic 1 1 1 Negative Genetic
MIC12 YBR262C Component of the MICOS complex genetic 1 1 1 Negative Genetic
ECM4 YKR076W S-glutathionyl-(chloro)hydroquinone reductase (GS-HQR) genetic 1 1 1 Positive Genetic
GPI10 YGL142C Integral membrane protein involved in GPI anchor synthesis genetic 1 1 1 Negative Genetic
LCL2 YLR104W Putative protein of unknown function genetic 1 1 1 Negative Genetic
ERG8 YMR220W Phosphomevalonate kinase genetic 1 1 1 Negative Genetic
HST2 YPL015C Cytoplasmic NAD(+)-dependent protein deacetylase genetic 1 1 1 Synthetic Growth Defect
NCE101 YJL205C Protein of unknown function genetic 1 1 1 Negative Genetic
RME1 YGR044C Zinc finger protein involved in control of meiosis genetic 1 1 1 Negative Genetic
PET20 YPL159C Mitochondrial protein genetic 1 1 1 Negative Genetic
RMD9 YGL107C Mitochondrial protein that controls mitochondrial gene expression genetic 1 1 1 Negative Genetic