MKS1 |
YNL076W |
Pleiotropic negative transcriptional regulator |
physical |
9 |
3 |
9 |
Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western |
TOR1 |
YJR066W |
PIK-related protein kinase and rapamycin target |
genetic |
6 |
3 |
5 |
Phenotypic Suppression, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic |
BMH2 |
YDR099W |
14-3-3 protein, minor isoform |
physical |
6 |
2 |
4 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western |
NBP2 |
YDR162C |
Protein involved in the HOG (high osmolarity glycerol) pathway |
genetic |
4 |
4 |
4 |
Synthetic Lethality, Synthetic Growth Defect, Negative Genetic, Positive Genetic |
RTG1 |
YOL067C |
Transcription factor (bHLH) involved in interorganelle communication |
genetic |
4 |
2 |
4 |
Synthetic Rescue, Positive Genetic, Positive Genetic, Positive Genetic |
CIT1 |
YNR001C |
Mitochondrial citrate synthase |
genetic |
4 |
2 |
4 |
Phenotypic Suppression, Negative Genetic, Negative Genetic, Negative Genetic |
LST8 |
YNL006W |
Protein required for the transport of Gap1p |
genetic |
4 |
3 |
3 |
Positive Genetic, Phenotypic Suppression, Synthetic Rescue, Positive Genetic |
BMH1 |
YER177W |
14-3-3 protein, major isoform |
physical |
4 |
2 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western |
ARO1 |
YDR127W |
Pentafunctional arom protein |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
GCN3 |
YKR026C |
Alpha subunit of translation initiation factor eIF2B |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
DEP1 |
YAL013W |
Component of the Rpd3L histone deacetylase complex |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
HOM2 |
YDR158W |
Aspartic beta semi-aldehyde dehydrogenase |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
RMD1 |
YDL001W |
Cytoplasmic protein required for sporulation |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
CRD1 |
YDL142C |
Cardiolipin synthase |
genetic |
3 |
3 |
3 |
Phenotypic Suppression, Phenotypic Enhancement, Synthetic Lethality |
MKS1 |
YNL076W |
Pleiotropic negative transcriptional regulator |
genetic |
3 |
2 |
3 |
Synthetic Rescue, Phenotypic Suppression, Phenotypic Suppression |
SNF3 |
YDL194W |
Plasma membrane low glucose sensor, regulates glucose transport |
genetic |
3 |
2 |
3 |
Synthetic Growth Defect, Negative Genetic, Negative Genetic |
GCN2 |
YDR283C |
Protein kinase |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
GCR2 |
YNL199C |
Transcriptional activator of genes involved in glycolysis |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
THR4 |
YCR053W |
Threonine synthase |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
IRC25 |
YLR021W |
Component of a heterodimeric Poc4p-Irc25p chaperone |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
GTR2 |
YGR163W |
Subunit of a TORC1-stimulating GTPase and the EGO/GSE complex |
genetic |
3 |
3 |
2 |
Synthetic Lethality, Synthetic Growth Defect, Negative Genetic |
SPT7 |
YBR081C |
Subunit of the SAGA transcriptional regulatory complex |
physical |
3 |
3 |
2 |
Affinity Capture-Western, Co-purification, Affinity Capture-MS |
RRP1 |
YDR087C |
Essential evolutionarily conserved nucleolar protein |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
NAP1 |
YKR048C |
Histone chaperone and assembly chaperone for Rps6a/b |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
ISW2 |
YOR304W |
ATP-dependent DNA translocase involved in chromatin remodeling |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
DUR12 |
YBR208C |
Urea amidolyase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
GPT2 |
YKR067W |
Glycerol-3-phosphate/dihydroxyacetone phosphate sn-1 acyltransferase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
PHO23 |
YNL097C |
Component of the Rpd3L histone deacetylase complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
PIN4 |
YBL051C |
Protein involved in G2/M phase progression and response to DNA damage |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
FIN1 |
YDR130C |
Spindle pole body-related intermediate filament protein |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
MDH1 |
YKL085W |
Mitochondrial malate dehydrogenase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
MCX1 |
YBR227C |
Non-proteolytic ATPase of the AAA family |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
MEK1 |
YOR351C |
Meiosis-specific serine/threonine protein kinase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
ASM4 |
YDL088C |
FG-nucleoporin component of central core of nuclear pore complex (NPC) |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
SSD1 |
YDR293C |
Translational repressor |
genetic |
3 |
1 |
2 |
Positive Genetic, Positive Genetic, Positive Genetic |
YGR266W |
YGR266W |
Protein of unknown function |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
SRB2 |
YHR041C |
Subunit of the RNA polymerase II mediator complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
TMA108 |
YIL137C |
Ribosome-associated, nascent chain binding factor |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
YKR018C |
YKR018C |
Protein of unknown function |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
WHI2 |
YOR043W |
Negative regulator of TORC1 in response to limiting leucine |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
SPE3 |
YPR069C |
Spermidine synthase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
STB5 |
YHR178W |
Transcription factor |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
ERV15 |
YBR210W |
Protein involved in export of proteins from the endoplasmic reticulum |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
CYB5 |
YNL111C |
Cytochrome b5 |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
CTP1 |
YBR291C |
Mitochondrial inner membrane citrate transporter |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
MRS2 |
YOR334W |
Mitochondrial inner membrane Mg(2+) channel |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
ALT1 |
YLR089C |
Alanine transaminase (glutamic pyruvic transaminase) |
genetic |
3 |
1 |
2 |
Positive Genetic, Positive Genetic, Positive Genetic |
PTM1 |
YKL039W |
Protein of unknown function |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
PIB2 |
YGL023C |
Phosphatidylinositol 3-phosphate binding protein |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
LGE1 |
YPL055C |
Protein involved in histone H2B ubiquitination |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
HPT1 |
YDR399W |
Dimeric hypoxanthine-guanine phosphoribosyltransferase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
PET8 |
YNL003C |
S-adenosylmethionine transporter of the mitochondrial inner membrane |
genetic |
3 |
1 |
2 |
Positive Genetic, Positive Genetic, Positive Genetic |
POL2 |
YNL262W |
Catalytic subunit of DNA polymerase (II) epsilon |
genetic |
2 |
2 |
2 |
Synthetic Rescue, Negative Genetic |
GCN5 |
YGR252W |
Catalytic subunit of ADA and SAGA histone acetyltransferase complexes |
genetic |
2 |
2 |
2 |
Negative Genetic, Phenotypic Enhancement |
FZO1 |
YBR179C |
Mitofusin, protein involved in mitochondrial outer membrane fusion |
genetic |
2 |
2 |
2 |
Synthetic Rescue, Phenotypic Suppression |
YAP1 |
YML007W |
Basic leucine zipper (bZIP) transcription factor |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
SCH9 |
YHR205W |
AGC family protein kinase |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Phenotypic Suppression |
UCC1 |
YLR224W |
F-box protein and component of SCF ubiquitin ligase complexes |
genetic |
2 |
2 |
2 |
Positive Genetic, Synthetic Rescue |
NOP16 |
YER002W |
Constituent of 66S pre-ribosomal particles |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ADH1 |
YOL086C |
Alcohol dehydrogenase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
KRE33 |
YNL132W |
Acetyltransferase required for biogenesis of small ribosomal subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
ORC2 |
YBR060C |
Subunit of the origin recognition complex (ORC) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
DIP5 |
YPL265W |
Dicarboxylic amino acid permease |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
KDX1 |
YKL161C |
Protein kinase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RMT2 |
YDR465C |
Arginine N5 methyltransferase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MEH1 |
YKR007W |
Subunit of the EGO/GSE complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
GDH1 |
YOR375C |
NADP(+)-dependent glutamate dehydrogenase |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
GTR1 |
YML121W |
Subunit of a TORC1-stimulating GTPase and the EGO/GSE complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
DAL81 |
YIR023W |
Positive regulator of genes in multiple nitrogen degradation pathways |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RVS167 |
YDR388W |
Calmodulin-binding actin-associated protein |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
SPT16 |
YGL207W |
Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
SLM4 |
YBR077C |
Subunit of the EGO/GSE complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
THI74 |
YDR438W |
Mitochondrial transporter repressible by thiamine |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
TSA2 |
YDR453C |
Stress inducible cytoplasmic thioredoxin peroxidase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
VMA8 |
YEL051W |
Subunit D of the V1 peripheral membrane domain of V-ATPase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
UBP13 |
YBL067C |
Ubiquitin-specific protease that cleaves Ub-protein fusions |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
STE50 |
YCL032W |
Adaptor protein for various signaling pathways |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RVS161 |
YCR009C |
Amphiphysin-like lipid raft protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
VMS1 |
YDR049W |
Peptidyl-tRNA hydrolase that releases stalled peptides from ribosomes, |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SCW4 |
YGR279C |
Cell wall protein with similarity to glucanases |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SEC22 |
YLR268W |
R-SNARE protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
TOF1 |
YNL273W |
Subunit of a replication-pausing checkpoint complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SUR1 |
YPL057C |
Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RXT2 |
YBR095C |
Component of the histone deacetylase Rpd3L complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
TPM1 |
YNL079C |
Major isoform of tropomyosin |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
REC8 |
YPR007C |
Meiosis-specific component of the sister chromatid cohesion complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
DID2 |
YKR035W-A |
Class E protein of the vacuolar protein-sorting (Vps) pathway |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PAR32 |
YDL173W |
Low complexity protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
LYS20 |
YDL182W |
Homocitrate synthase isozyme and functions in DNA repair |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
DSF1 |
YEL070W |
Mannitol dehydrogenase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
NPR1 |
YNL183C |
Protein kinase |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
ERG3 |
YLR056W |
C-5 sterol desaturase |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
LDO16 |
YMR148W |
Protein of unknown function with possible role in spore wall assembly |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MFM1 |
YPL060W |
Mitochondrial inner membrane magnesium transporter |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MRX19 |
YDL183C |
Protein that may form an active mitochondrial KHE system |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
CDC24 |
YAL041W |
Guanine nucleotide exchange factor (GEF) for Cdc42p |
genetic |
2 |
2 |
1 |
Positive Genetic, Negative Genetic |
SPC3 |
YLR066W |
Subunit of signal peptidase complex |
genetic |
2 |
2 |
1 |
Negative Genetic, Positive Genetic |
SPC98 |
YNL126W |
Component of the microtubule-nucleating Tub4p (gamma-tubulin) complex |
genetic |
2 |
2 |
1 |
Negative Genetic, Positive Genetic |
SEC72 |
YLR292C |
Non-essential subunit of Sec63 complex |
genetic |
2 |
2 |
1 |
Negative Genetic, Positive Genetic |
ESA1 |
YOR244W |
Catalytic subunit of the histone acetyltransferase complex (NuA4) |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
RPN11 |
YFR004W |
Metalloprotease subunit of 19S regulatory particle |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
GCN20 |
YFR009W |
Positive regulator of the Gcn2p kinase activity |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
RAD14 |
YMR201C |
Subunit of Nucleotide Excision Repair Factor 1 (NEF1) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
SWC4 |
YGR002C |
Component of the Swr1p complex that incorporates Htz1p into chromatin |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
YDR124W |
YDR124W |
Mitochondrial protein of unknown function |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
ZRT2 |
YLR130C |
Low-affinity zinc transporter of the plasma membrane |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
SCS7 |
YMR272C |
Sphingolipid alpha-hydroxylase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
SUP35 |
YDR172W |
Translation termination factor eRF3 |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
SUI2 |
YJR007W |
Alpha subunit of the translation initiation factor eIF2 |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
ESC1 |
YMR219W |
Protein involved in telomeric silencing |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
LEU1 |
YGL009C |
Isopropylmalate isomerase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
GEF1 |
YJR040W |
Voltage-gated chloride channel |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
ARO2 |
YGL148W |
Bifunctional chorismate synthase and flavin reductase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
DEG1 |
YFL001W |
tRNA:pseudouridine synthase |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
MPS3 |
YJL019W |
Nuclear envelope protein |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
UGA3 |
YDL170W |
Transcriptional activator for GABA-dependent induction of GABA genes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
CDC73 |
YLR418C |
Component of the Paf1p complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
CHD1 |
YER164W |
Chromatin remodeler that regulates various aspects of transcription |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CHD1 |
YER164W |
Chromatin remodeler that regulates various aspects of transcription |
genetic |
1 |
1 |
1 |
Negative Genetic |
CWC25 |
YNL245C |
Splicing factor required for the first step of pre-mRNA splicing |
genetic |
1 |
1 |
1 |
Positive Genetic |
CBF5 |
YLR175W |
Pseudouridine synthase catalytic subunit of box H/ACA snoRNPs |
genetic |
1 |
1 |
1 |
Positive Genetic |
MCM22 |
YJR135C |
Outer kinetochore protein and component of the Ctf3 subcomplex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PSF1 |
YDR013W |
Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPB3 |
YIL021W |
RNA polymerase II third largest subunit B44 |
genetic |
1 |
1 |
1 |
Positive Genetic |
POB3 |
YML069W |
Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
ESF1 |
YDR365C |
Nucleolar protein involved in pre-rRNA processing |
genetic |
1 |
1 |
1 |
Negative Genetic |
DRS1 |
YLL008W |
Nucleolar DEAD-box protein required for ribosome assembly and function |
genetic |
1 |
1 |
1 |
Negative Genetic |
NOP9 |
YJL010C |
Essential subunit of U3-containing 90S preribosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
POP4 |
YBR257W |
Subunit of both RNase MRP and nuclear RNase P |
genetic |
1 |
1 |
1 |
Positive Genetic |
BRR2 |
YER172C |
RNA-dependent ATPase RNA helicase (DEIH box) |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRP46 |
YPL151C |
Member of the NineTeen Complex (NTC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
POL5 |
YEL055C |
Protein involved in 60S assembly and pre-40S AFs recycling |
genetic |
1 |
1 |
1 |
Negative Genetic |
NOP58 |
YOR310C |
Protein involved in producing mature rRNAs and snoRNAs |
genetic |
1 |
1 |
1 |
Negative Genetic |
RRP5 |
YMR229C |
RNA binding protein involved in synthesis of 18S and 5.8S rRNAs |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MTR4 |
YJL050W |
RNA duplex-sensing translocase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RCK2 |
YLR248W |
Protein kinase involved in response to oxidative and osmotic stress |
genetic |
1 |
1 |
1 |
Negative Genetic |
LSM1 |
YJL124C |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
PAT1 |
YCR077C |
Deadenylation-dependent mRNA-decapping factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
PAB1 |
YER165W |
Poly(A) binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
CSL4 |
YNL232W |
Exosome non-catalytic core component |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPC34 |
YNR003C |
RNA polymerase III subunit C34 |
genetic |
1 |
1 |
1 |
Negative Genetic |
RSC4 |
YKR008W |
Component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
DST1 |
YGL043W |
General transcription elongation factor TFIIS |
genetic |
1 |
1 |
1 |
Negative Genetic |
PWP1 |
YLR196W |
Protein with WD-40 repeats involved in rRNA processing |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPN11 |
YFR004W |
Metalloprotease subunit of 19S regulatory particle |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPN8 |
YOR261C |
Essential non-ATPase regulatory subunit of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
HCR1 |
YLR192C |
eIF3j component of translation initiation factor 3 (eIF3) |
genetic |
1 |
1 |
1 |
Negative Genetic |
NIP1 |
YMR309C |
eIF3c subunit of the eukaryotic translation initiation factor 3 (eIF3) |
genetic |
1 |
1 |
1 |
Negative Genetic |
ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
genetic |
1 |
1 |
1 |
Negative Genetic |
GCD2 |
YGR083C |
Delta subunit of the translation initiation factor eIF2B |
genetic |
1 |
1 |
1 |
Negative Genetic |
IMD3 |
YLR432W |
Inosine monophosphate dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ALA1 |
YOR335C |
Cytoplasmic and mitochondrial alanyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Positive Genetic |
BCP1 |
YDR361C |
Essential nuclear chaperone for ribosomal protein Rpl23p |
genetic |
1 |
1 |
1 |
Negative Genetic |
HGH1 |
YGR187C |
Chaperone protein for translation factor eEF2 |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARP3 |
YJR065C |
Essential component of the Arp2/3 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
BUD14 |
YAR014C |
Protein involved in bud-site selection |
genetic |
1 |
1 |
1 |
Positive Genetic |
CDC14 |
YFR028C |
Protein phosphatase required for mitotic exit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CDC28 |
YBR160W |
Cyclin-dependent kinase (CDK) catalytic subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC11 |
YJR076C |
Component of the septin ring that is required for cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC3 |
YLR314C |
Component of the septin ring that is required for cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
DBP10 |
YDL031W |
Putative ATP-dependent RNA helicase of the DEAD-box protein family |
genetic |
1 |
1 |
1 |
Negative Genetic |
HDA1 |
YNL021W |
Catalytic subunit of class II HDA1 histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CTK1 |
YKL139W |
Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) |
genetic |
1 |
1 |
1 |
Positive Genetic |
DCP1 |
YOL149W |
Subunit of the Dcp1p-Dcp2p decapping enzyme complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
GCD7 |
YLR291C |
Beta subunit of translation initiation factor eIF2B |
physical |
1 |
1 |
1 |
Two-hybrid |
GLO3 |
YER122C |
ADP-ribosylation factor GTPase activating protein (ARF GAP) |
genetic |
1 |
1 |
1 |
Positive Genetic |
HHF1 |
YBR009C |
Histone H4 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HHF2 |
YNL030W |
Histone H4 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HST1 |
YOL068C |
NAD(+)-dependent histone deacetylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
HTB2 |
YBL002W |
Histone H2B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ACK1 |
YDL203C |
Protein that functions in the cell wall integrity pathway |
genetic |
1 |
1 |
1 |
Positive Genetic |
HSL1 |
YKL101W |
Nim1p-related protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
KRR1 |
YCL059C |
Nucleolar protein required for rRNA synthesis and ribosomal assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
CRM1 |
YGR218W |
Nuclear export factor, exportin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
LSM2 |
YBL026W |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
LSM7 |
YNL147W |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
ENO2 |
YHR174W |
Enolase II, a phosphopyruvate hydratase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MAK5 |
YBR142W |
Essential nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
MED11 |
YMR112C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
MED6 |
YHR058C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
HSC82 |
YMR186W |
Cytoplasmic chaperone of the Hsp90 family |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
NHP10 |
YDL002C |
Non-essential INO80 chromatin remodeling complex subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
GIM3 |
YNL153C |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
APM1 |
YPL259C |
Mu1-like medium subunit of the AP-1 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
PPH3 |
YDR075W |
Catalytic subunit of protein phosphatase PP4 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
HSP82 |
YPL240C |
Hsp90 chaperone |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
HTA1 |
YDR225W |
Histone H2A |
genetic |
1 |
1 |
1 |
Negative Genetic |
HTA2 |
YBL003C |
Histone H2A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
REF2 |
YDR195W |
RNA-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRPL6 |
YHR147C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPD3 |
YNL330C |
Histone deacetylase, component of both the Rpd3S and Rpd3L complexes |
genetic |
1 |
1 |
1 |
Positive Genetic |
CTI6 |
YPL181W |
Component of the Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC6 |
YJL194W |
Essential ATP-binding protein required for DNA replication |
genetic |
1 |
1 |
1 |
Positive Genetic |
PIL1 |
YGR086C |
Eisosome core component |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BZZ1 |
YHR114W |
SH3 domain protein implicated in regulating actin polymerization |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRP18 |
YGR006W |
Splicing factor and component of snRNP U5 |
genetic |
1 |
1 |
1 |
Negative Genetic |
NEM1 |
YHR004C |
Probable catalytic subunit of Nem1p-Spo7p phosphatase holoenzyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
GCN5 |
YGR252W |
Catalytic subunit of ADA and SAGA histone acetyltransferase complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NGG1 |
YDR176W |
Subunit of chromatin modifying histone acetyltransferase complexes |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
CRN1 |
YLR429W |
Coronin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GAS1 |
YMR307W |
Beta-1,3-glucanosyltransferase required for cell wall assembly |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ACO1 |
YLR304C |
Aconitase |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
LSP1 |
YPL004C |
Eisosome core component |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ADR1 |
YDR216W |
Carbon source-responsive zinc-finger transcription factor |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
ACH1 |
YBL015W |
Protein with CoA transferase activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
IDH1 |
YNL037C |
Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase |
genetic |
1 |
1 |
1 |
Positive Genetic |
HTB1 |
YDR224C |
Histone H2B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HTB1 |
YDR224C |
Histone H2B |
genetic |
1 |
1 |
1 |
Negative Genetic |
HIR3 |
YJR140C |
Subunit of the HIR complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
GRR1 |
YJR090C |
F-box protein component of an SCF ubiquitin-ligase complex |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
FET3 |
YMR058W |
Ferro-O2-oxidoreductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
AAT2 |
YLR027C |
Cytosolic aspartate aminotransferase involved in nitrogen metabolism |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
LCP5 |
YER127W |
Essential protein involved in maturation of 18S rRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC9 |
YDL164C |
DNA ligase I found in nucleus and mitochondria |
genetic |
1 |
1 |
1 |
Positive Genetic |
ECM10 |
YEL030W |
Heat shock protein of the Hsp70 family |
genetic |
1 |
1 |
1 |
Positive Genetic |
ATG42 |
YBR139W |
Vacuolar serine-type carboxypeptidase |
genetic |
1 |
1 |
1 |
Positive Genetic |
FUM1 |
YPL262W |
Fumarase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MET30 |
YIL046W |
F-box protein containing five copies of the WD40 motif |
genetic |
1 |
1 |
1 |
Negative Genetic |
RNA1 |
YMR235C |
GTPase activating protein (GAP) for Gsp1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
CTF13 |
YMR094W |
Subunit of the CBF3 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ISN1 |
YOR155C |
Inosine 5'-monophosphate (IMP)-specific 5'-nucleotidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
DNL4 |
YOR005C |
DNA ligase required for nonhomologous end-joining (NHEJ) |
genetic |
1 |
1 |
1 |
Positive Genetic |
CWC21 |
YDR482C |
Protein involved in RNA splicing by the spliceosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
KSP1 |
YHR082C |
Serine/threonine protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
HIR2 |
YOR038C |
Subunit of HIR nucleosome assembly complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CTF4 |
YPR135W |
Chromatin-associated protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
NOP53 |
YPL146C |
Nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
LSM8 |
YJR022W |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
APA1 |
YCL050C |
AP4A phosphorylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
EAP1 |
YKL204W |
eIF4E-associated protein, competes with eIF4G for binding to eIF4E |
genetic |
1 |
1 |
1 |
Positive Genetic |
DBF2 |
YGR092W |
Ser/Thr kinase involved in transcription and stress response |
genetic |
1 |
1 |
1 |
Positive Genetic |
BUB3 |
YOR026W |
Kinetochore checkpoint WD40 repeat protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
FUS3 |
YBL016W |
Mitogen-activated serine/threonine protein kinase involved in mating |
genetic |
1 |
1 |
1 |
Negative Genetic |
PHO86 |
YJL117W |
Endoplasmic reticulum (ER) resident protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
CIT2 |
YCR005C |
Citrate synthase, peroxisomal isozyme involved in glyoxylate cycle |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
CIT2 |
YCR005C |
Citrate synthase, peroxisomal isozyme involved in glyoxylate cycle |
genetic |
1 |
1 |
1 |
Dosage Rescue |
BIM1 |
YER016W |
Microtubule plus end-tracking protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
IPK1 |
YDR315C |
Inositol 1,3,4,5,6-pentakisphosphate 2-kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
LST7 |
YGR057C |
Subunit of the Lst4p-Lst7p GTPase activating protein complex for Gtr2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
GCN4 |
YEL009C |
bZIP transcriptional activator of amino acid biosynthetic genes |
genetic |
1 |
1 |
1 |
Negative Genetic |
PCL8 |
YPL219W |
Cyclin |
genetic |
1 |
1 |
1 |
Negative Genetic |
PKC1 |
YBL105C |
Protein serine/threonine kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC34 |
YDR054C |
Ubiquitin-conjugating enzyme (E2) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
AIM18 |
YHR198C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
PPA2 |
YMR267W |
Mitochondrial inorganic pyrophosphatase |
genetic |
1 |
1 |
1 |
Positive Genetic |
CNL1 |
YDR357C |
Subunit of the BLOC-1 complex involved in endosomal maturation |
genetic |
1 |
1 |
1 |
Positive Genetic |
DSE3 |
YOR264W |
Daughter cell-specific protein, may help establish daughter fate |
genetic |
1 |
1 |
1 |
Negative Genetic |
COG4 |
YPR105C |
Essential component of the conserved oligomeric Golgi complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
AIM4 |
YBR194W |
Protein proposed to be associated with the nuclear pore complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
NFI1 |
YOR156C |
SUMO E3 ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
BRE5 |
YNR051C |
Ubiquitin protease cofactor |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARP6 |
YLR085C |
Actin-related protein that binds nucleosomes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HOS3 |
YPL116W |
Trichostatin A-insensitive homodimeric histone deacetylase (HDAC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRP2 |
YNR011C |
RNA-dependent DExD/H-box ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS1A |
YLR441C |
Ribosomal protein of the small (40S) subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS8A |
YBL072C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS7A |
YOR096W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS7A |
YOR096W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
RAD9 |
YDR217C |
DNA damage-dependent checkpoint protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
CLC1 |
YGR167W |
Clathrin light chain |
genetic |
1 |
1 |
1 |
Negative Genetic |
DBF4 |
YDR052C |
Regulatory subunit of Cdc7p-Dbf4p kinase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
DCD1 |
YHR144C |
Deoxycytidine monophosphate (dCMP) deaminase |
genetic |
1 |
1 |
1 |
Negative Genetic |
CBF2 |
YGR140W |
Essential kinetochore protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
OST3 |
YOR085W |
Gamma subunit of the oligosaccharyltransferase complex of the ER lumen |
genetic |
1 |
1 |
1 |
Positive Genetic |
UBP8 |
YMR223W |
Ubiquitin-specific protease component of the SAGA acetylation complex |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
STD1 |
YOR047C |
Protein involved in control of glucose-regulated gene expression |
physical |
1 |
1 |
1 |
Two-hybrid |
YRA1 |
YDR381W |
Nuclear polyadenylated RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YNL208W |
YNL208W |
Protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
VPS71 |
YML041C |
Nucleosome-binding component of the SWR1 complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RTG2 |
YGL252C |
Sensor of mitochondrial dysfunction |
physical |
1 |
1 |
1 |
Two-hybrid |
SGF73 |
YGL066W |
Subunit of DUBm module of SAGA and SLIK |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SSB2 |
YNL209W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
1 |
1 |
1 |
Co-purification |
VAM6 |
YDL077C |
Guanine nucleotide exchange factor for the GTPase Gtr1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SHR3 |
YDL212W |
Endoplasmic reticulum packaging chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
YFH1 |
YDL120W |
Mitochondrial matrix iron chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
TCP1 |
YDR212W |
Alpha subunit of chaperonin-containing T-complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SRP101 |
YDR292C |
Signal recognition particle (SRP) receptor alpha subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
UTR2 |
YEL040W |
Chitin transglycosylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SRO7 |
YPR032W |
Effector of Rab GTPase Sec4p |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC9 |
YGR009C |
t-SNARE protein required for secretory vesicle-plasma membrane fusion |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC63 |
YOR254C |
Essential subunit of Sec63 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPT8 |
YLR055C |
Subunit of the SAGA transcriptional regulatory complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
VMA21 |
YGR105W |
Integral membrane protein required for V-ATPase function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
VOA1 |
YGR106C |
ER protein that functions in assembly of the V0 sector of V-ATPase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SNN1 |
YNL086W |
Subunit of the BLOC-1 complex involved in endosomal maturation |
genetic |
1 |
1 |
1 |
Positive Genetic |
SLT2 |
YHR030C |
Serine/threonine MAP kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS4 |
YPR173C |
AAA-ATPase involved in multivesicular body (MVB) protein sorting |
genetic |
1 |
1 |
1 |
Negative Genetic |
SAC1 |
YKL212W |
Phosphatidylinositol phosphate phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
TLG2 |
YOL018C |
Syntaxin-like t-SNARE |
genetic |
1 |
1 |
1 |
Negative Genetic |
STH1 |
YIL126W |
ATPase component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
THS1 |
YIL078W |
Threonyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Positive Genetic |
TAO3 |
YIL129C |
Component of the RAM signaling network |
genetic |
1 |
1 |
1 |
Positive Genetic |
TIF34 |
YMR146C |
eIF3i subunit of the eukaryotic translation initiation factor 3 (eIF3) |
genetic |
1 |
1 |
1 |
Positive Genetic |
TAF3 |
YPL011C |
TFIID subunit (47 kDa) |
genetic |
1 |
1 |
1 |
Positive Genetic |
SMX3 |
YPR182W |
Core Sm protein Sm F |
genetic |
1 |
1 |
1 |
Positive Genetic |
YCL049C |
YCL049C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
SUM1 |
YDR310C |
Transcriptional repressor that regulates middle-sporulation genes |
genetic |
1 |
1 |
1 |
Positive Genetic |
YHP1 |
YDR451C |
Homeobox transcriptional repressor |
genetic |
1 |
1 |
1 |
Positive Genetic |
SPF1 |
YEL031W |
P-type ATPase, ion transporter of the ER membrane |
genetic |
1 |
1 |
1 |
Positive Genetic |
SOM1 |
YEL059C-A |
Subunit of the mitochondrial inner membrane peptidase (IMP) |
genetic |
1 |
1 |
1 |
Positive Genetic |
YER079W |
YER079W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
YER175W-A |
YER175W-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
YHB1 |
YGR234W |
Nitric oxide oxidoreductase |
genetic |
1 |
1 |
1 |
Positive Genetic |
YHK8 |
YHR048W |
Presumed antiporter of the major facilitator superfamily |
genetic |
1 |
1 |
1 |
Positive Genetic |
SEC28 |
YIL076W |
Epsilon-COP subunit of the coatomer |
genetic |
1 |
1 |
1 |
Positive Genetic |
YLR156C-A |
YLR156C-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
YMR030W-A |
YMR030W-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
SNO1 |
YMR095C |
Protein of unconfirmed function |
genetic |
1 |
1 |
1 |
Positive Genetic |
URE2 |
YNL229C |
Nitrogen catabolite repression transcriptional regulator |
genetic |
1 |
1 |
1 |
Positive Genetic |
VPS21 |
YOR089C |
Endosomal Rab family GTPase |
genetic |
1 |
1 |
1 |
Positive Genetic |
TFC1 |
YBR123C |
Subunit of RNA polymerase III transcription initiation factor complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SNU56 |
YDR240C |
Component of U1 snRNP required for mRNA splicing via spliceosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
SNM1 |
YDR478W |
Ribonuclease MRP complex subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
UTP8 |
YGR128C |
Nucleolar protein required for export of tRNAs from the nucleus |
genetic |
1 |
1 |
1 |
Negative Genetic |
YPP1 |
YGR198W |
Cargo-transport protein involved in endocytosis |
genetic |
1 |
1 |
1 |
Negative Genetic |
URA6 |
YKL024C |
Uridylate kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
TOR2 |
YKL203C |
PIK-related protein kinase and rapamycin target |
genetic |
1 |
1 |
1 |
Negative Genetic |
YHC1 |
YLR298C |
Component of the U1 snRNP complex required for pre-mRNA splicing |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEN1 |
YLR430W |
ATP-dependent 5' to 3' RNA/DNA and DNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
TIF11 |
YMR260C |
Translation initiation factor eIF1A |
genetic |
1 |
1 |
1 |
Negative Genetic |
TFB2 |
YPL122C |
Subunit of TFIIH and nucleotide excision repair factor 3 complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC8 |
YPR055W |
Essential 121 kDa subunit of the exocyst complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SGV1 |
YPR161C |
Cyclin (Bur2p)-dependent protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
UBP14 |
YBR058C |
Ubiquitin-specific protease |
genetic |
1 |
1 |
1 |
Negative Genetic |
YBR285W |
YBR285W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YBR298C-A |
YBR298C-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
SFA1 |
YDL168W |
Bifunctional alcohol dehydrogenase and formaldehyde dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
YDL177C |
YDL177C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
VMA1 |
YDL185W |
Subunit A of the V1 peripheral membrane domain of V-ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
YDR169C-A |
YDR169C-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
SBH2 |
YER019C-A |
Ssh1p-Sss1p-Sbh2p complex component |
genetic |
1 |
1 |
1 |
Negative Genetic |
YFL012W |
YFL012W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YBR225W |
YBR225W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPE1 |
YKL184W |
Ornithine decarboxylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
YGR035C |
YGR035C |
Putative protein of unknown function, potential Cdc28p substrate |
genetic |
1 |
1 |
1 |
Negative Genetic |
UBR1 |
YGR184C |
E3 ubiquitin ligase (N-recognin) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SER2 |
YGR208W |
Phosphoserine phosphatase of the phosphoglycerate pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
YGR210C |
YGR210C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
TDA3 |
YHR009C |
Putative oxidoreductase involved in late endosome to Golgi transport |
genetic |
1 |
1 |
1 |
Negative Genetic |
YJL068C |
YJL068C |
Esterase that can function as an S-formylglutathione hydrolase |
genetic |
1 |
1 |
1 |
Negative Genetic |
YJL107C |
YJL107C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
TSA1 |
YML028W |
Thioredoxin peroxidase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SBA1 |
YKL117W |
Co-chaperone that binds and regulates Hsp90 family chaperones |
genetic |
1 |
1 |
1 |
Negative Genetic |
SET3 |
YKR029C |
Defining member of the SET3 histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
YLL006W-A |
YLL006W-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
STM1 |
YLR150W |
Protein required for optimal translation under nutrient stress |
genetic |
1 |
1 |
1 |
Negative Genetic |
YLR412C-A |
YLR412C-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
URA4 |
YLR420W |
Dihydroorotase |
genetic |
1 |
1 |
1 |
Negative Genetic |
YML020W |
YML020W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
SUB1 |
YMR039C |
Transcriptional regulator |
genetic |
1 |
1 |
1 |
Negative Genetic |
WSC2 |
YNL283C |
Sensor-transducer of the stress-activated PKC1-MPK1 signaling pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
SKP2 |
YNL311C |
F-box protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YOR296W |
YOR296W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPO19 |
YPL130W |
Meiosis-specific prospore protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
SVS1 |
YPL163C |
Cell wall and vacuolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
SET6 |
YPL165C |
SET domain protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
RTG3 |
YBL103C |
bHLH/Zip transcription factor for retrograde (RTG) and TOR pathways |
genetic |
1 |
1 |
1 |
Positive Genetic |
YNG1 |
YOR064C |
Subunit of the NuA3 histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
SIC1 |
YLR079W |
Cyclin-dependent kinase inhibitor (CKI) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SET2 |
YJL168C |
Histone methyltransferase with a role in transcriptional elongation |
genetic |
1 |
1 |
1 |
Positive Genetic |
SIN3 |
YOL004W |
Component of both the Rpd3S and Rpd3L histone deacetylase complexes |
genetic |
1 |
1 |
1 |
Positive Genetic |
SEC14 |
YMR079W |
Phosphatidylinositol/phosphatidylcholine transfer protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
SNL1 |
YIL016W |
Ribosome-associated protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC16 |
YPL085W |
COPII vesicle coat protein required for ER transport vesicle budding |
genetic |
1 |
1 |
1 |
Negative Genetic |
UGA3 |
YDL170W |
Transcriptional activator for GABA-dependent induction of GABA genes |
genetic |
1 |
1 |
1 |
Negative Genetic |
SMC1 |
YFL008W |
Subunit of the multiprotein cohesin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
TRS65 |
YGR166W |
Component of transport protein particle (TRAPP) complex II |
genetic |
1 |
1 |
1 |
Negative Genetic |
UBA3 |
YPR066W |
Protein that activates Rub1p (NEDD8) before neddylation |
genetic |
1 |
1 |
1 |
Negative Genetic |
SMC6 |
YLR383W |
Subunit of the SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SLX4 |
YLR135W |
Endonuclease involved in processing DNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
TUB4 |
YLR212C |
Gamma-tubulin |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SGS1 |
YMR190C |
RecQ family nucleolar DNA helicase |
genetic |
1 |
1 |
1 |
Positive Genetic |
MGM1 |
YOR211C |
Mitochondrial GTPase, present in complex with Ugo1p and Fzo1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
MBF1 |
YOR298C-A |
Transcriptional coactivator |
genetic |
1 |
1 |
1 |
Negative Genetic |
BAG7 |
YOR134W |
Rho GTPase activating protein (RhoGAP) |
genetic |
1 |
1 |
1 |
Negative Genetic |
GAL10 |
YBR019C |
UDP-glucose-4-epimerase |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
CSG2 |
YBR036C |
Endoplasmic reticulum membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
CAT8 |
YMR280C |
Zinc cluster transcriptional activator |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
INP53 |
YOR109W |
Polyphosphatidylinositol phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MAC1 |
YMR021C |
Copper-sensing transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
GPR1 |
YDL035C |
Plasma membrane G protein coupled receptor (GPCR) |
genetic |
1 |
1 |
1 |
Positive Genetic |
CUS2 |
YNL286W |
Putative checkpoint factor in transcription |
genetic |
1 |
1 |
1 |
Positive Genetic |
DJP1 |
YIR004W |
ER-associated chaperone involved in protein targeting |
genetic |
1 |
1 |
1 |
Negative Genetic |
CMR2 |
YOR093C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
GFD2 |
YCL036W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL31A |
YDL075W |
Ribosomal 60S subunit protein L31A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
REV3 |
YPL167C |
Catalytic subunit of DNA polymerase zeta |
genetic |
1 |
1 |
1 |
Negative Genetic |
CCH1 |
YGR217W |
Voltage-gated high-affinity calcium channel |
genetic |
1 |
1 |
1 |
Negative Genetic |
HHT2 |
YNL031C |
Histone H3 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NUP188 |
YML103C |
Subunit of the inner ring of the nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPL11A |
YPR102C |
Ribosomal 60S subunit protein L11A |
genetic |
1 |
1 |
1 |
Positive Genetic |
ENT1 |
YDL161W |
Epsin-like protein involved in endocytosis and actin patch assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
HUB1 |
YNR032C-A |
Ubiquitin-like protein modifier |
genetic |
1 |
1 |
1 |
Negative Genetic |
DBP6 |
YNR038W |
Essential protein involved in ribosome biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
EAF7 |
YNL136W |
Subunit of the NuA4 histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPS18A |
YDR450W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ORM2 |
YLR350W |
Protein that mediates sphingolipid homeostasis |
genetic |
1 |
1 |
1 |
Positive Genetic |
PXA2 |
YKL188C |
Subunit of heterodimeric peroxisomal ABC transport complex, with Pxa1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
PAC1 |
YOR269W |
Regulator of dynein, involved in intracellular transport |
genetic |
1 |
1 |
1 |
Negative Genetic |
APM2 |
YHL019C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
ATX1 |
YNL259C |
Cytosolic copper metallochaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
PSG1 |
YKL077W |
Protein that promotes the transport and maturation of Pma1 with Exp1 |
genetic |
1 |
1 |
1 |
Positive Genetic |
INP1 |
YMR204C |
Peripheral membrane protein of peroxisomes |
genetic |
1 |
1 |
1 |
Negative Genetic |
DDR2 |
YOL052C-A |
Multi-stress response protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
RFA2 |
YNL312W |
Subunit of heterotrimeric Replication Protein A (RPA) |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPL40B |
YKR094C |
Ubiquitin-ribosomal 60S subunit protein L40B fusion protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
DIC1 |
YLR348C |
Mitochondrial dicarboxylate carrier |
genetic |
1 |
1 |
1 |
Negative Genetic |
ASE1 |
YOR058C |
Mitotic spindle midzone-localized microtubule bundling protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
NFS1 |
YCL017C |
Cysteine desulfurase involved in iron-sulfur cluster biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
KCS1 |
YDR017C |
Inositol hexakisphosphate and inositol heptakisphosphate kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PUF4 |
YGL014W |
Member of the PUF protein family |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRPL17 |
YNL252C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
IRC22 |
YEL001C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
COQ11 |
YLR290C |
Putative oxidoreductase, subunit of Coenzyme Q biosynthetic complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
BRL1 |
YHR036W |
Essential nuclear envelope/ER integral membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
FCY21 |
YER060W |
Putative purine-cytosine permease |
genetic |
1 |
1 |
1 |
Positive Genetic |
BNA1 |
YJR025C |
3-hydroxyanthranilic acid dioxygenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PPX1 |
YHR201C |
Exopolyphosphatase |
genetic |
1 |
1 |
1 |
Positive Genetic |
RSM25 |
YIL093C |
Mitochondrial ribosomal protein of the small subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
GCD14 |
YJL125C |
Subunit of tRNA (1-methyladenosine) methyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
GIS2 |
YNL255C |
Translational activator for mRNAs with internal ribosome entry sites |
genetic |
1 |
1 |
1 |
Negative Genetic |
CSS1 |
YIL169C |
Protein of unknown function, secreted when constitutively expressed |
genetic |
1 |
1 |
1 |
Negative Genetic |
CUP9 |
YPL177C |
Homeodomain-containing transcriptional repressor |
genetic |
1 |
1 |
1 |
Negative Genetic |
JID1 |
YPR061C |
Probable Hsp40p co-chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
LDB19 |
YOR322C |
Alpha-arrestin, Ub-ligase adaptor for Rsp5p |
genetic |
1 |
1 |
1 |
Negative Genetic |
OCA5 |
YHL029C |
Cytoplasmic protein required for replication of Brome mosaic virus |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPL26A |
YLR344W |
Ribosomal 60S subunit protein L26A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS19A |
YOL121C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CAB1 |
YDR531W |
Pantothenate kinase, ATP:D-pantothenate 4'-phosphotransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARV1 |
YLR242C |
Cortical ER protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
PHO91 |
YNR013C |
Low-affinity vacuolar phosphate transporter |
genetic |
1 |
1 |
1 |
Positive Genetic |
ISF1 |
YMR081C |
Serine-rich, hydrophilic protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
AIM39 |
YOL053W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
PUF2 |
YPR042C |
PUF family mRNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
ERG24 |
YNL280C |
C-14 sterol reductase |
genetic |
1 |
1 |
1 |
Positive Genetic |
RGS2 |
YOR107W |
Negative regulator of glucose-induced cAMP signaling |
genetic |
1 |
1 |
1 |
Negative Genetic |
DER1 |
YBR201W |
ER membrane protein that promotes export of misfolded polypeptides |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPS27A |
YKL156W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
KTR1 |
YOR099W |
Alpha-1,2-mannosyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
DNF2 |
YDR093W |
Aminophospholipid translocase (flippase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
EEB1 |
YPL095C |
Acyl-coenzymeA:ethanol O-acyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
NEO1 |
YIL048W |
Phospholipid translocase (flippase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
MDM32 |
YOR147W |
Mitochondrial inner membrane protein with similarity to Mdm31p |
genetic |
1 |
1 |
1 |
Positive Genetic |
LSO2 |
YGR169C-A |
Ribosome-associated protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
BIG1 |
YHR101C |
Integral membrane protein of the endoplasmic reticulum |
genetic |
1 |
1 |
1 |
Positive Genetic |
PXP1 |
YEL020C |
Peroxisomal matrix protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
MTC2 |
YKL098W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
AVL9 |
YLR114C |
Conserved protein involved in exocytic transport from the Golgi |
genetic |
1 |
1 |
1 |
Positive Genetic |
AAD15 |
YOL165C |
Putative aryl-alcohol dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
GIS3 |
YLR094C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
IML2 |
YJL082W |
Protein required for clearance of inclusion bodies |
genetic |
1 |
1 |
1 |
Negative Genetic |
PUN1 |
YLR414C |
Plasma membrane protein with a role in cell wall integrity |
genetic |
1 |
1 |
1 |
Positive Genetic |
RCE1 |
YMR274C |
Type II CAAX prenyl protease |
genetic |
1 |
1 |
1 |
Negative Genetic |
IFM1 |
YOL023W |
Mitochondrial translation initiation factor 2 |
genetic |
1 |
1 |
1 |
Positive Genetic |
DPL1 |
YDR294C |
Dihydrosphingosine phosphate lyase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS6B |
YBR181C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
EFM4 |
YIL064W |
Lysine methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
FMP30 |
YPL103C |
Protein with a role in maintaining mitochondrial morphology |
genetic |
1 |
1 |
1 |
Negative Genetic |
HMX1 |
YLR205C |
ER localized heme oxygenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
GPI1 |
YGR216C |
Membrane protein involved in the synthesis of GlcNAc-PI |
genetic |
1 |
1 |
1 |
Negative Genetic |
LAS21 |
YJL062W |
Mannose-ethanolamine phosphotransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPS15 |
YOL040C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RCF1 |
YML030W |
Cytochrome c oxidase subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
PPM1 |
YDR435C |
Carboxyl methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MNL2 |
YLR057W |
Putative mannosidase involved in ER-associated protein degradation |
genetic |
1 |
1 |
1 |
Negative Genetic |
PUG1 |
YER185W |
Plasma membrane protein involved in protoprophyrin and heme transport |
genetic |
1 |
1 |
1 |
Positive Genetic |
PAU16 |
YKL224C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |