Standard name Systematic name Name description Description
RTT10 YPL183C WD40 domain-containing protein involved in endosomal recycling WD40 domain-containing protein involved in endosomal recycling; forms a complex with Rrt2p that functions in the retromer-mediated pathway for recycling internalized cell-surface proteins; interacts with Trm7p for 2'-O-methylation of N34 of substrate tRNAs; has a role in regulation of Ty1 transposition; human ortholog is WDR6
Visualize the interactome of RTT10
Links to external databases:
SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.969 0.963 0.979

GFP localization & abundance

GFP localization GFP abundance
no data no data

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
RTT10 2 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
TRM1 YDR120C tRNA methyltransferase genetic 6 2 4 Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
TRM7 YBR061C 2'-O-ribose methyltransferase physical 5 4 4 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Co-crystal Structure, Co-purification
SRC1 YML034W Inner nuclear membrane protein genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
TRM732 YMR259C Protein involved in 2'-O-methylation of C32 of substrate tRNAs genetic 3 2 2 Synthetic Growth Defect, Synthetic Growth Defect, Phenotypic Enhancement
RIC1 YLR039C Protein involved in retrograde transport to the cis-Golgi network genetic 2 2 2 Positive Genetic, Negative Genetic
YPT6 YLR262C Rab family GTPase genetic 2 2 2 Positive Genetic, Negative Genetic
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 2 1 2 Negative Genetic, Negative Genetic
SPC24 YMR117C Component of the kinetochore-associated Ndc80 complex genetic 2 1 2 Negative Genetic, Negative Genetic
SCS7 YMR272C Sphingolipid alpha-hydroxylase genetic 2 1 2 Negative Genetic, Negative Genetic
UBP3 YER151C Ubiquitin-specific protease that cleaves Ub-protein fusions genetic 2 1 2 Negative Genetic, Negative Genetic
POR1 YNL055C Mitochondrial porin (voltage-dependent anion channel) genetic 2 1 2 Negative Genetic, Negative Genetic
LOS1 YKL205W Nuclear pore protein genetic 2 1 2 Negative Genetic, Negative Genetic
APE2 YKL157W Aminopeptidase yscII genetic 2 1 2 Negative Genetic, Negative Genetic
DEG1 YFL001W tRNA:pseudouridine synthase genetic 2 1 2 Negative Genetic, Negative Genetic
PSD1 YNL169C Phosphatidylserine decarboxylase of the mitochondrial inner membrane genetic 2 1 2 Negative Genetic, Negative Genetic
PPM2 YOL141W AdoMet-dependent tRNA methyltransferase genetic 2 1 2 Negative Genetic, Negative Genetic
TUB4 YLR212C Gamma-tubulin genetic 2 2 1 Synthetic Rescue, Synthetic Growth Defect
SSE1 YPL106C ATPase component of heat shock protein Hsp90 chaperone complex physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
SSB1 YDL229W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
TRM11 YOL124C Catalytic subunit of adoMet-dependent tRNA methyltransferase complex genetic 2 1 1 Negative Genetic, Negative Genetic
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
POB3 YML069W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) genetic 1 1 1 Negative Genetic
RPL10 YLR075W Ribosomal 60S subunit protein L10 genetic 1 1 1 Positive Genetic
NSE4 YDL105W Component of the SMC5-SMC6 complex genetic 1 1 1 Negative Genetic
NUG1 YER006W GTPase that associates with nuclear 60S pre-ribosomes genetic 1 1 1 Negative Genetic
MTR4 YJL050W RNA duplex-sensing translocase genetic 1 1 1 Negative Genetic
PRP3 YDR473C Splicing factor genetic 1 1 1 Negative Genetic
NPL3 YDR432W RNA-binding protein genetic 1 1 1 Synthetic Rescue
RPC25 YKL144C RNA polymerase III subunit C25 genetic 1 1 1 Negative Genetic
RPC31 YNL151C RNA polymerase III subunit C31 genetic 1 1 1 Negative Genetic
ILS1 YBL076C Cytoplasmic isoleucine-tRNA synthetase genetic 1 1 1 Negative Genetic
CEX1 YOR112W Component of nuclear aminoacylation-dependent tRNA export pathway genetic 1 1 1 Negative Genetic
RPN1 YHR027C Non-ATPase base subunit of the 19S RP of the 26S proteasome genetic 1 1 1 Positive Genetic
RPT3 YDR394W ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Positive Genetic
REB1 YBR049C RNA polymerase I enhancer binding protein genetic 1 1 1 Positive Genetic
RTT10 YPL183C WD40 domain-containing protein involved in endosomal recycling physical 1 1 1 Affinity Capture-MS
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone genetic 1 1 1 Negative Genetic
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p physical 1 1 1 Affinity Capture-MS
THR4 YCR053W Threonine synthase physical 1 1 1 Reconstituted Complex
SPP381 YBR152W mRNA splicing factor, component of U4/U6.U5 tri-snRNP genetic 1 1 1 Positive Genetic
TIM8 YJR135W-A Mitochondrial intermembrane space protein genetic 1 1 1 Negative Genetic
VPS1 YKR001C Dynamin-like GTPase required for vacuolar sorting genetic 1 1 1 Positive Genetic
VPS71 YML041C Nucleosome-binding component of the SWR1 complex genetic 1 1 1 Negative Genetic
YTA12 YMR089C Mitochondrial inner membrane m-AAA protease component genetic 1 1 1 Negative Genetic
TIM18 YOR297C Component of the mitochondrial TIM22 complex genetic 1 1 1 Negative Genetic
YME1 YPR024W Catalytic subunit of i-AAA protease complex genetic 1 1 1 Negative Genetic
SRO7 YPR032W Effector of Rab GTPase Sec4p genetic 1 1 1 Negative Genetic
SNF7 YLR025W One of four subunits of the ESCRT-III complex genetic 1 1 1 Phenotypic Enhancement
SNX41 YDR425W Sorting nexin genetic 1 1 1 Phenotypic Enhancement
YHC1 YLR298C Component of the U1 snRNP complex required for pre-mRNA splicing genetic 1 1 1 Positive Genetic
SFB3 YHR098C Component of the Sec23p-Sfb3p heterodimer of the COPII vesicle coat genetic 1 1 1 Positive Genetic
SLA2 YNL243W Adaptor protein that links actin to clathrin and endocytosis genetic 1 1 1 Positive Genetic
TAF12 YDR145W Subunit (61/68 kDa) of TFIID and SAGA complexes genetic 1 1 1 Negative Genetic
SAD1 YFR005C Conserved zinc-finger domain protein involved in pre-mRNA splicing genetic 1 1 1 Negative Genetic
SPC42 YKL042W Central plaque component of spindle pole body (SPB) genetic 1 1 1 Negative Genetic
SMC4 YLR086W Subunit of the condensin complex genetic 1 1 1 Negative Genetic
SCT1 YBL011W Glycerol 3-phosphate/dihydroxyacetone phosphate sn-1 acyltransferase genetic 1 1 1 Negative Genetic
YBL100W-C YBL100W-C Putative protein of unknown function genetic 1 1 1 Negative Genetic
RXT2 YBR095C Component of the histone deacetylase Rpd3L complex genetic 1 1 1 Negative Genetic
SHE3 YBR130C Protein adaptor between Myo4p and the She2p-mRNA complex genetic 1 1 1 Negative Genetic
YCL001W-B YCL001W-B Putative protein of unknown function genetic 1 1 1 Negative Genetic
ZRG8 YER033C Protein of unknown function genetic 1 1 1 Negative Genetic
YER053C-A YER053C-A Protein of unknown function genetic 1 1 1 Negative Genetic
TYW3 YGL050W tRNA methyltransferase required for synthesis of wybutosine genetic 1 1 1 Negative Genetic
YJR096W YJR096W Xylose and arabinose reductase genetic 1 1 1 Negative Genetic
UBP11 YKR098C Ubiquitin-specific protease genetic 1 1 1 Negative Genetic
XDJ1 YLR090W Chaperone with a role in facilitating mitochondrial protein import genetic 1 1 1 Negative Genetic
YOL107W YOL107W Putative protein of unknown function genetic 1 1 1 Negative Genetic
YOR385W YOR385W Putative protein of unknown function genetic 1 1 1 Negative Genetic
SWC5 YBR231C Component of the SWR1 complex genetic 1 1 1 Negative Genetic
SGF73 YGL066W Subunit of DUBm module of SAGA and SLIK genetic 1 1 1 Negative Genetic
SNF4 YGL115W Activating gamma subunit of the AMP-activated Snf1p kinase complex genetic 1 1 1 Negative Genetic
VAM7 YGL212W Vacuolar SNARE protein genetic 1 1 1 Negative Genetic
VPS24 YKL041W One of four subunits of the ESCRT-III complex genetic 1 1 1 Negative Genetic
SAC1 YKL212W Phosphatidylinositol phosphate phosphatase genetic 1 1 1 Negative Genetic
SND2 YLR065C Protein involved in SRP-independent targeting of substrates to the ER genetic 1 1 1 Negative Genetic
STM1 YLR150W Protein required for optimal translation under nutrient stress genetic 1 1 1 Negative Genetic
SWS2 YNL081C Putative mitochondrial ribosomal protein of the small subunit genetic 1 1 1 Negative Genetic
SIN3 YOL004W Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 1 1 1 Negative Genetic
YOL036W YOL036W Protein of unknown function genetic 1 1 1 Negative Genetic
YPR084W YPR084W Putative protein of unknown function genetic 1 1 1 Negative Genetic
YPR108W-A YPR108W-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
VPS51 YKR020W Component of the GARP (Golgi-associated retrograde protein) complex genetic 1 1 1 Negative Genetic
TEF2 YBR118W Translational elongation factor EF-1 alpha genetic 1 1 1 Negative Genetic
SIC1 YLR079W Cyclin-dependent kinase inhibitor (CKI) genetic 1 1 1 Negative Genetic
TPT1 YOL102C tRNA 2'-phosphotransferase that catalyzes final step in tRNA splicing genetic 1 1 1 Negative Genetic
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 1 1 1 Positive Genetic
ADE4 YMR300C Phosphoribosylpyrophosphate amidotransferase (PRPPAT) genetic 1 1 1 Negative Genetic
ARP3 YJR065C Essential component of the Arp2/3 complex genetic 1 1 1 Negative Genetic
CAF130 YGR134W Subunit of the CCR4-NOT transcriptional regulatory complex genetic 1 1 1 Positive Genetic
CDC11 YJR076C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Negative Genetic
CDC3 YLR314C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Positive Genetic
NOG2 YNR053C Putative GTPase genetic 1 1 1 Positive Genetic
COX6 YHR051W Subunit VI of cytochrome c oxidase (Complex IV) genetic 1 1 1 Negative Genetic
FRS1 YLR060W Beta subunit of cytoplasmic phenylalanyl-tRNA synthetase genetic 1 1 1 Negative Genetic
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
LAS17 YOR181W Actin assembly factor genetic 1 1 1 Negative Genetic
MRPL10 YNL284C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
MRP10 YDL045W-A Mitochondrial ribosomal protein of the small subunit genetic 1 1 1 Negative Genetic
GEP3 YOR205C Protein required for mitochondrial ribosome small subunit biogenesis genetic 1 1 1 Negative Genetic
MGM101 YJR144W Protein with a role in mitochondrial DNA recombinational repair genetic 1 1 1 Negative Genetic
HTZ1 YOL012C Histone variant H2AZ genetic 1 1 1 Negative Genetic
POL1 YNL102W Catalytic subunit of the DNA polymerase I alpha-primase complex genetic 1 1 1 Synthetic Growth Defect
POP7 YBR167C Subunit of RNase MRP, nuclear RNase P and telomerase genetic 1 1 1 Negative Genetic
PRP31 YGR091W Splicing factor genetic 1 1 1 Negative Genetic
PRP6 YBR055C Splicing factor genetic 1 1 1 Negative Genetic
INO4 YOL108C Transcription factor involved in phospholipid synthesis genetic 1 1 1 Positive Genetic
PFK2 YMR205C Beta subunit of heterooctameric phosphofructokinase genetic 1 1 1 Negative Genetic
RAD1 YPL022W Single-stranded DNA endonuclease (with Rad10p) physical 1 1 1 Affinity Capture-MS
PUF3 YLL013C Protein of the mitochondrial outer surface physical 1 1 1 Affinity Capture-RNA
IRA2 YOL081W GTPase-activating protein genetic 1 1 1 Negative Genetic
HYP2 YEL034W Translation elongation factor eIF-5A genetic 1 1 1 Positive Genetic
PLN1 YKR046C Perilipin, involved in formation and stability of lipid droplets genetic 1 1 1 Negative Genetic
FYV10 YIL097W Subunit of GID complex genetic 1 1 1 Negative Genetic
PMA1 YGL008C Plasma membrane P2-type H+-ATPase genetic 1 1 1 Negative Genetic
ESL2 YKR096W hEST1A/B (SMG5/6)-like protein genetic 1 1 1 Negative Genetic
DSS1 YMR287C 3'-5' exoribonuclease genetic 1 1 1 Positive Genetic
ELA1 YNL230C Elongin A genetic 1 1 1 Negative Genetic
MRS6 YOR370C Rab escort protein genetic 1 1 1 Negative Genetic
MAK11 YKL021C Protein involved in an early step of 60S ribosomal subunit biogenesis genetic 1 1 1 Negative Genetic
FRS2 YFL022C Alpha subunit of cytoplasmic phenylalanyl-tRNA synthetase genetic 1 1 1 Negative Genetic
LHS1 YKL073W Molecular chaperone of the endoplasmic reticulum lumen genetic 1 1 1 Positive Genetic
LSC1 YOR142W Alpha subunit of succinyl-CoA ligase genetic 1 1 1 Negative Genetic
CIK1 YMR198W Kinesin-associated protein genetic 1 1 1 Positive Genetic
APA1 YCL050C AP4A phosphorylase genetic 1 1 1 Negative Genetic
CDC7 YDL017W S/T kinase and catalytic subunit of DDK (Dbf4-dependent kinase) genetic 1 1 1 Negative Genetic
ERG11 YHR007C Lanosterol 14-alpha-demethylase genetic 1 1 1 Negative Genetic
ESS1 YJR017C Peptidylprolyl-cis/trans-isomerase (PPIase) genetic 1 1 1 Negative Genetic
MTQ2 YDR140W S-adenosylmethionine-dependent methyltransferase physical 1 1 1 Affinity Capture-MS
BUD27 YFL023W Unconventional prefoldin protein involved in translation initiation genetic 1 1 1 Negative Genetic
CLN3 YAL040C G1 cyclin involved in cell cycle progression genetic 1 1 1 Negative Genetic
MCM10 YIL150C Essential chromatin-associated protein genetic 1 1 1 Negative Genetic
INO2 YDR123C Transcription factor genetic 1 1 1 Negative Genetic
HSP10 YOR020C Mitochondrial matrix co-chaperonin genetic 1 1 1 Negative Genetic
PKC1 YBL105C Protein serine/threonine kinase genetic 1 1 1 Negative Genetic
PPG1 YNR032W Serine protein phosphatase involved in formation of FAR complex genetic 1 1 1 Negative Genetic
ATG36 YJL185C Pex3p interacting protein, required for pexophagy genetic 1 1 1 Negative Genetic
PPA2 YMR267W Mitochondrial inorganic pyrophosphatase genetic 1 1 1 Negative Genetic
CDC21 YOR074C Thymidylate synthase genetic 1 1 1 Negative Genetic
RPS24A YER074W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
BRE5 YNR051C Ubiquitin protease cofactor genetic 1 1 1 Negative Genetic
CSE4 YKL049C Centromeric histone H3-like protein genetic 1 1 1 Negative Genetic
DCD1 YHR144C Deoxycytidine monophosphate (dCMP) deaminase genetic 1 1 1 Negative Genetic
OST2 YOR103C Epsilon subunit of the oligosaccharyltransferase complex genetic 1 1 1 Negative Genetic
BET1 YIL004C Type II membrane protein required for vesicular transport genetic 1 1 1 Negative Genetic
KAR2 YJL034W ATPase involved in protein import into the ER genetic 1 1 1 Positive Genetic
OST4 YDL232W Subunit of the oligosaccharyltransferase complex of the ER lumen genetic 1 1 1 Negative Genetic
BUD2 YKL092C GTPase activating factor for Rsr1p/Bud1p genetic 1 1 1 Negative Genetic
DAL80 YKR034W Negative regulator of genes in multiple nitrogen degradation pathways genetic 1 1 1 Negative Genetic
PRP16 YKR086W DEAH-box RNA helicase genetic 1 1 1 Negative Genetic
ATP10 YLR393W Assembly factor for the F0 sector of mitochondrial F1F0 ATP synthase genetic 1 1 1 Negative Genetic
BET4 YJL031C Alpha subunit of Type II geranylgeranyltransferase genetic 1 1 1 Positive Genetic
MIP1 YOR330C Mitochondrial DNA polymerase gamma genetic 1 1 1 Negative Genetic
EAF7 YNL136W Subunit of the NuA4 histone acetyltransferase complex genetic 1 1 1 Negative Genetic
RPL28 YGL103W Ribosomal 60S subunit protein L28 genetic 1 1 1 Positive Genetic
ERG5 YMR015C C-22 sterol desaturase genetic 1 1 1 Positive Genetic
PRP24 YMR268C Splicing factor that reanneals snRNPs during spliceosome recycling genetic 1 1 1 Negative Genetic
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 1 1 1 Positive Genetic
KXD1 YGL079W Subunit of the BLOC-1 complex involved in endosomal maturation genetic 1 1 1 Negative Genetic
DDR48 YMR173W DNA damage-responsive protein genetic 1 1 1 Negative Genetic
PMR1 YGL167C High affinity Ca2+/Mn2+ P-type ATPase genetic 1 1 1 Positive Genetic
MSS1 YMR023C Mitochondrial protein genetic 1 1 1 Negative Genetic
NOP19 YGR251W Ribosome biogenesis factor genetic 1 1 1 Negative Genetic
PPX1 YHR201C Exopolyphosphatase genetic 1 1 1 Negative Genetic
GTT3 YEL017W Protein of unknown function may be involved in glutathione metabolism genetic 1 1 1 Negative Genetic
AHC2 YCR082W Component of the ADA histone acetyltransferase complex genetic 1 1 1 Negative Genetic
PEX32 YBR168W Peroxisomal integral membrane protein genetic 1 1 1 Negative Genetic
OCA5 YHL029C Cytoplasmic protein required for replication of Brome mosaic virus genetic 1 1 1 Negative Genetic
DUS1 YML080W Dihydrouridine synthase genetic 1 1 1 Negative Genetic
PTP1 YDL230W Phosphotyrosine-specific protein phosphatase genetic 1 1 1 Negative Genetic
PRM10 YJL108C Pheromone-regulated protein genetic 1 1 1 Positive Genetic
GPI19 YDR437W Subunit of GPI-GlcNAc transferase involved in synthesis of GlcNAc-PI genetic 1 1 1 Positive Genetic
RRT2 YBR246W Methylesterase performing penultimate step of diphthamide biosynthesis physical 1 1 1 Affinity Capture-Western
CPD1 YGR247W Cyclic nucleotide phosphodiesterase genetic 1 1 1 Negative Genetic
RCR2 YDR003W Vacuolar ubiquitin ligase-substrate adaptor genetic 1 1 1 Negative Genetic
LDB18 YLL049W Component of the dynactin complex genetic 1 1 1 Negative Genetic
MDM32 YOR147W Mitochondrial inner membrane protein with similarity to Mdm31p genetic 1 1 1 Positive Genetic
AAD16 YFL057C Putative aryl alcohol dehydrogenase genetic 1 1 1 Negative Genetic
MSC1 YML128C Protein of unknown function genetic 1 1 1 Negative Genetic
IZH2 YOL002C Plasma membrane receptor for plant antifungal osmotin genetic 1 1 1 Synthetic Growth Defect
AIM19 YIL087C Protein of unknown function genetic 1 1 1 Negative Genetic
MMM1 YLL006W ER integral membrane protein, ERMES complex subunit genetic 1 1 1 Negative Genetic
RPS28B YLR264W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
PUL4 YNR063W Putative zinc-cluster transcription factor genetic 1 1 1 Negative Genetic
MMT1 YMR177W Putative metal transporter involved in mitochondrial iron accumulation genetic 1 1 1 Negative Genetic
IRS4 YKR019C EH domain-containing protein genetic 1 1 1 Negative Genetic
IMA4 YJL221C Alpha-glucosidase genetic 1 1 1 Negative Genetic
GAT4 YIR013C Protein containing GATA family zinc finger motifs genetic 1 1 1 Negative Genetic
PAU5 YFL020C Member of the seripauperin multigene family genetic 1 1 1 Negative Genetic
RTR2 YDR066C Protein of unknown function genetic 1 1 1 Negative Genetic