GEnome-wide tool for Multi-scale Modeling
data Extraction and Representation
for Saccharomyces cerevisiae

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.

Standard name	Systematic name	Name description	Type	#Experiments	#Methods	#Publications	Evidence
PUF3	YLL013C	Protein of the mitochondrial outer surface	physical	3	1	3	Affinity Capture-RNA, Affinity Capture-RNA, Affinity Capture-RNA
CDC73	YLR418C	Component of the Paf1p complex	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
LEO1	YOR123C	Component of the Paf1 complex	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
PSY2	YNL201C	Subunit of protein phosphatase PP4 complex	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
ARO1	YDR127W	Pentafunctional arom protein	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
ATP11	YNL315C	Molecular chaperone	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
ELP2	YGR200C	Subunit of Elongator complex	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
EAF3	YPR023C	Component of the Rpd3S histone deacetylase complex	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
GCN1	YGL195W	Positive regulator of the Gcn2p kinase activity	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
MED1	YPR070W	Subunit of the RNA polymerase II mediator complex	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
HTZ1	YOL012C	Histone variant H2AZ	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
IES5	YER092W	Non-essential INO80 chromatin remodeling complex subunit	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
PAN2	YGL094C	Catalytic subunit of the Pan2p-Pan3p poly(A)-ribonuclease complex	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
GCN20	YFR009W	Positive regulator of the Gcn2p kinase activity	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
RAD52	YML032C	Protein involved in homologous recombination	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
DEP1	YAL013W	Component of the Rpd3L histone deacetylase complex	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
PHO23	YNL097C	Component of the Rpd3L histone deacetylase complex	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
RPP2B	YDR382W	Ribosomal protein P2 beta	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
SET2	YJL168C	Histone methyltransferase with a role in transcriptional elongation	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
SIF2	YBR103W	WD40 repeat-containing subunit of Set3C histone deacetylase complex	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
SIN3	YOL004W	Component of both the Rpd3S and Rpd3L histone deacetylase complexes	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
PFK2	YMR205C	Beta subunit of heterooctameric phosphofructokinase	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
BCK1	YJL095W	MAPKKK acting in the protein kinase C signaling pathway	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
IRA2	YOL081W	GTPase-activating protein	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
PBS2	YJL128C	MAP kinase kinase of the HOG signaling pathway	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
PMA2	YPL036W	Plasma membrane H+-ATPase	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
BUD13	YGL174W	Subunit of the RES complex	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
HOG1	YLR113W	Mitogen-activated protein kinase involved in osmoregulation	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
SLT2	YHR030C	Serine/threonine MAP kinase	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
ICP55	YER078C	Mitochondrial aminopeptidase	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
MIC19	YFR011C	Component of the MICOS complex	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
GCR2	YNL199C	Transcriptional activator of genes involved in glycolysis	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
MET16	YPR167C	3'-phosphoadenylsulfate reductase	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
MRX1	YER077C	Protein that associates with mitochondrial ribosome	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
BUD27	YFL023W	Unconventional prefoldin protein involved in translation initiation	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
CLG1	YGL215W	Cyclin-like protein that interacts with Pho85p	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
RIM101	YHL027W	Cys2His2 zinc-finger transcriptional repressor	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
DAL81	YIR023W	Positive regulator of genes in multiple nitrogen degradation pathways	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
SNF6	YHL025W	Subunit of the SWI/SNF chromatin remodeling complex	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
CHS5	YLR330W	Component of the exomer complex	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
RIM20	YOR275C	Protein involved in proteolytic activation of Rim101p	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
IXR1	YKL032C	Transcriptional repressor that regulates hypoxic genes during normoxia	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
RMI1	YPL024W	Subunit of the RecQ (Sgs1p) - Topo III (Top3p) complex	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
PAM17	YKR065C	Constituent of the TIM23 complex	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
PUF4	YGL014W	Member of the PUF protein family	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
RIM8	YGL045W	Protein involved in proteolytic activation of Rim101p	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
ETR1	YBR026C	2-enoyl thioester reductase	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
IZH3	YLR023C	Membrane protein involved in zinc ion homeostasis	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
RPP1A	YDL081C	Ribosomal stalk protein P1 alpha	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
RPL43A	YPR043W	Ribosomal 60S subunit protein L43A	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
ARO2	YGL148W	Bifunctional chorismate synthase and flavin reductase	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
RPL14A	YKL006W	Ribosomal 60S subunit protein L14A	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
RIM13	YMR154C	Calpain-like cysteine protease	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
MPS3	YJL019W	Nuclear envelope protein	genetic	2	1	1	Synthetic Rescue, Synthetic Rescue
RPS16B	YDL083C	Protein component of the small (40S) ribosomal subunit	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
DFG16	YOR030W	Probable multiple transmembrane protein	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
SIC1	YLR079W	Cyclin-dependent kinase inhibitor (CKI)	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
CHO2	YGR157W	Phosphatidylethanolamine methyltransferase (PEMT)	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
ATG41	YPL250C	Protein of unknown function	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
SSE1	YPL106C	ATPase component of heat shock protein Hsp90 chaperone complex	physical	2	1	1	Affinity Capture-MS, Affinity Capture-MS
SSA1	YAL005C	ATPase involved in protein folding and NLS-directed nuclear transport	physical	2	1	1	Affinity Capture-MS, Affinity Capture-MS
SSB1	YDL229W	Cytoplasmic ATPase that is a ribosome-associated molecular chaperone	physical	2	1	1	Affinity Capture-MS, Affinity Capture-MS
STB5	YHR178W	Transcription factor	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
YME1	YPR024W	Catalytic subunit of i-AAA protease complex	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
YGR122W	YGR122W	Protein that may be involved in pH regulation	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
THR1	YHR025W	Homoserine kinase	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
UPS1	YLR193C	Phosphatidic acid transfer protein	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
TOM70	YNL121C	Component of the TOM (translocase of outer membrane) complex	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
SWI4	YER111C	DNA binding component of the SBF complex (Swi4p-Swi6p)	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
SPT8	YLR055C	Subunit of the SAGA transcriptional regulatory complex	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
URE2	YNL229C	Nitrogen catabolite repression transcriptional regulator	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
TAZ1	YPR140W	Lyso-phosphatidylcholine acyltransferase	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
XRN1	YGL173C	Evolutionarily-conserved 5'-3' exonuclease	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
VPS74	YDR372C	Golgi PI4K effector, PtdIns4P sensor, and retention receptor	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
FMC1	YIL098C	Mitochondrial matrix protein	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
MSC1	YML128C	Protein of unknown function	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
CRD1	YDL142C	Cardiolipin synthase	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
CLD1	YGR110W	Mitochondrial cardiolipin-specific phospholipase	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
MGR2	YPL098C	Subunit of the TIM23 translocase complex	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
ILT1	YDR090C	Protein of unknown function	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
SPT10	YJL127C	Histone H3 acetylase with a role in transcriptional regulation	regulation	1	1	1	DNA to cDNA expression microarray evidence
RSM23	YGL129C	Mitochondrial ribosomal protein of the small subunit	physical	1	1	1	Proximity Label-MS
ACT1	YFL039C	Actin, structural protein in cytoskeleton	genetic	1	1	1	Synthetic Haploinsufficiency
CCR4	YAL021C	Component of the CCR4-NOT transcriptional complex	physical	1	1	1	Affinity Capture-RNA
NAB2	YGL122C	Nuclear polyadenylated RNA-binding protein	physical	1	1	1	Affinity Capture-MS
ASF1	YJL115W	Nucleosome assembly factor	genetic	1	1	1	Synthetic Lethality
BUD31	YCR063W	Component of the SF3b subcomplex of the U2 snRNP	genetic	1	1	1	Positive Genetic
DHH1	YDL160C	Cytoplasmic DEAD-box helicase and mRNA decapping activator	physical	1	1	1	Affinity Capture-RNA
ISW1	YBR245C	ATPase subunit of imitation-switch (ISWI) class chromatin remodelers	physical	1	1	1	Affinity Capture-RNA
LSM2	YBL026W	Lsm (Like Sm) protein	physical	1	1	1	Two-hybrid
HSC82	YMR186W	Cytoplasmic chaperone of the Hsp90 family	genetic	1	1	1	Synthetic Growth Defect
MRP1	YDR347W	Mitochondrial ribosomal protein of the small subunit	physical	1	1	1	Proximity Label-MS
MRP51	YPL118W	Mitochondrial ribosomal protein of the small subunit	physical	1	1	1	Proximity Label-MS
MAM33	YIL070C	Acidic protein of the mitochondrial matrix	physical	1	1	1	Affinity Capture-MS
HSP82	YPL240C	Hsp90 chaperone	genetic	1	1	1	Synthetic Growth Defect
PUB1	YNL016W	Poly (A)+ RNA-binding protein	physical	1	1	1	Affinity Capture-MS
PMA1	YGL008C	Plasma membrane P2-type H+-ATPase	genetic	1	1	1	Negative Genetic
RAD6	YGL058W	Ubiquitin-conjugating enzyme (E2)	genetic	1	1	1	Synthetic Growth Defect
PEX13	YLR191W	Peroxisomal importomer complex component	physical	1	1	1	Two-hybrid
EXO1	YOR033C	5'-3' exonuclease and flap-endonuclease	genetic	1	1	1	Negative Genetic
MPT5	YGL178W	mRNA-binding protein of the PUF family	physical	1	1	1	Affinity Capture-RNA
GEM1	YAL048C	Outer mitochondrial membrane GTPase, subunit of the ERMES complex	genetic	1	1	1	Negative Genetic
OPY2	YPR075C	Integral membrane protein that acts as a membrane anchor for Ste50p	genetic	1	1	1	Negative Genetic
PIK1	YNL267W	Phosphatidylinositol 4-kinase	genetic	1	1	1	Synthetic Growth Defect
SCH9	YHR205W	AGC family protein kinase	genetic	1	1	1	Synthetic Growth Defect
VAM6	YDL077C	Guanine nucleotide exchange factor for the GTPase Gtr1p	physical	1	1	1	Affinity Capture-MS
SSC1	YJR045C	Hsp70 family ATPase	physical	1	1	1	Affinity Capture-MS
TTI2	YJR136C	Subunit of the ASTRA complex, involved in chromatin remodeling	genetic	1	1	1	Negative Genetic