VPS15 |
YBR097W |
Serine/threonine protein kinase involved in vacuolar protein sorting |
physical |
10 |
5 |
6 |
Affinity Capture-Western, Co-fractionation, Two-hybrid, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Co-crystal Structure |
VPS30 |
YPL120W |
Subunit of phosphatidylinositol (PtdIns) 3-kinase complexes I and II |
physical |
7 |
2 |
6 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
ATG14 |
YBR128C |
Autophagy-specific subunit of phosphatidylinositol 3-kinase complex I |
physical |
5 |
2 |
4 |
Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western |
ATG38 |
YLR211C |
Homodimeric subunit of autophagy-specific PtdIns-3-kinase complex I |
physical |
5 |
4 |
2 |
Affinity Capture-MS, Affinity Capture-Western, Two-hybrid, Reconstituted Complex, Reconstituted Complex |
VPS38 |
YLR360W |
Part of a Vps34p phosphatidylinositol 3-kinase complex |
physical |
4 |
2 |
4 |
Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
GPA1 |
YHR005C |
Subunit of G protein involved in pheromone response |
physical |
2 |
2 |
1 |
Affinity Capture-Western, Reconstituted Complex |
HDA1 |
YNL021W |
Catalytic subunit of class II HDA1 histone deacetylase complex |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
EPL1 |
YFL024C |
Subunit of NuA4, an essential histone H4/H2A acetyltransferase complex |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
XBP1 |
YIL101C |
Transcriptional repressor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
BRE1 |
YDL074C |
E3 ubiquitin ligase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
CDC48 |
YDL126C |
AAA ATPase with protein-unfoldase activity |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SPT16 |
YGL207W |
Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PEP1 |
YBL017C |
Type I transmembrane sorting receptor for multiple vacuolar hydrolases |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ASF1 |
YJL115W |
Nucleosome assembly factor |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
CHC1 |
YGL206C |
Clathrin heavy chain |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CTF18 |
YMR078C |
Subunit of a complex with Ctf8p |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
EMP24 |
YGL200C |
Component of the p24 complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ERP1 |
YAR002C-A |
Member of the p24 family involved in ER to Golgi transport |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
FKS1 |
YLR342W |
Catalytic subunit of 1,3-beta-D-glucan synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
FTH1 |
YBR207W |
Putative high affinity iron transporter |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ERV25 |
YML012W |
Member of the p24 family involved in ER to Golgi transport |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ISW1 |
YBR245C |
ATPase subunit of imitation-switch (ISWI) class chromatin remodelers |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
MYO2 |
YOR326W |
Type V myosin motor involved in actin-based transport of cargos |
genetic |
1 |
1 |
1 |
Negative Genetic |
PEP3 |
YLR148W |
Component of CORVET membrane tethering complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PTC3 |
YBL056W |
Type 2C protein phosphatase (PP2C) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RAD51 |
YER095W |
Strand exchange protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RAD52 |
YML032C |
Protein involved in homologous recombination |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PIL1 |
YGR086C |
Eisosome core component |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SEC21 |
YNL287W |
Gamma subunit of coatomer |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SEC23 |
YPR181C |
GTPase-activating protein, stimulates the GTPase activity of Sar1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SEC17 |
YBL050W |
Alpha-SNAP cochaperone |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SLY1 |
YDR189W |
Hydrophilic protein involved in ER/Golgi vesicle trafficking |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ATG9 |
YDL149W |
Transmembrane protein involved in forming Cvt and autophagic vesicles |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
LTE1 |
YAL024C |
Protein similar to GDP/GTP exchange factors |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
VMA1 |
YDL185W |
Subunit A of the V1 peripheral membrane domain of V-ATPase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
VMA2 |
YBR127C |
Subunit B of V1 peripheral membrane domain of vacuolar H+-ATPase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
SNF7 |
YLR025W |
One of four subunits of the ESCRT-III complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PEP5 |
YMR231W |
Histone E3 ligase, component of CORVET membrane tethering complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TLG1 |
YDR468C |
Essential t-SNARE that mediates fusion of vesicles with the late Golgi |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
VPS1 |
YKR001C |
Dynamin-like GTPase required for vacuolar sorting |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RAD54 |
YGL163C |
DNA-dependent ATPase that stimulates strand exchange |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
GET1 |
YGL020C |
Subunit of the GET complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
GET2 |
YER083C |
Subunit of the GET complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ATG11 |
YPR049C |
Adapter protein for pexophagy and the Cvt targeting pathway |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RAD55 |
YDR076W |
Protein that stimulates strand exchange |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SEC18 |
YBR080C |
AAA ATPase and SNARE disassembly chaperone |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SAR1 |
YPL218W |
ARF family GTPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MRE11 |
YMR224C |
Nuclease subunit of the MRX complex with Rad50p and Xrs2p |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RAD50 |
YNL250W |
Subunit of MRX complex with Mre11p and Xrs2p |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SEC4 |
YFL005W |
Rab family GTPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ELG1 |
YOR144C |
Subunit of an alternative replication factor C complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
VPS21 |
YOR089C |
Endosomal Rab family GTPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RAD53 |
YPL153C |
DNA damage response kinase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
DID4 |
YKL002W |
Class E Vps protein of the ESCRT-III complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CSM1 |
YCR086W |
Nucleolar protein that mediates homolog segregation during meiosis I |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
VAM3 |
YOR106W |
Syntaxin-like vacuolar t-SNARE |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PEP12 |
YOR036W |
Target membrane receptor (t-SNARE) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BOS1 |
YLR078C |
v-SNARE (vesicle specific SNAP receptor) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CTF8 |
YHR191C |
Subunit of a complex with Ctf18p |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
NYV1 |
YLR093C |
v-SNARE component of the vacuolar SNARE complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BET1 |
YIL004C |
Type II membrane protein required for vesicular transport |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SED5 |
YLR026C |
cis-Golgi t-SNARE syntaxin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ERV41 |
YML067C |
Protein localized to COPII-coated vesicles |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SEC22 |
YLR268W |
R-SNARE protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SNC1 |
YAL030W |
Vesicle membrane receptor protein (v-SNARE) |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
SNC2 |
YOR327C |
Vesicle membrane receptor protein (v-SNARE) |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
PEP7 |
YDR323C |
Adaptor protein involved in vesicle-mediated vacuolar protein sorting |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
GOS1 |
YHL031C |
v-SNARE protein involved in Golgi transport |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SSO1 |
YPL232W |
Plasma membrane t-SNARE |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
EMP47 |
YFL048C |
Integral membrane component of ER-derived COPII-coated vesicles |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PRM8 |
YGL053W |
Pheromone-regulated protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
POL32 |
YJR043C |
Third subunit of DNA polymerase delta |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SLA2 |
YNL243W |
Adaptor protein that links actin to clathrin and endocytosis |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
SFT1 |
YKL006C-A |
Intra-Golgi v-SNARE |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
AKR1 |
YDR264C |
Palmitoyl transferase involved in protein palmitoylation |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
LRS4 |
YDR439W |
Nucleolar protein that forms a complex with Csm1p |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
TOR1 |
YJR066W |
PIK-related protein kinase and rapamycin target |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YIP1 |
YGR172C |
Integral membrane protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YPT32 |
YGL210W |
Rab family GTPase involved in the exocytic pathway |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YCK1 |
YHR135C |
Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YIF1 |
YNL263C |
Integral membrane protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YOP1 |
YPR028W |
Reticulon-interacting protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YPT52 |
YKR014C |
Endosomal Rab family GTPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YCK3 |
YER123W |
Palmitoylated vacuolar membrane-localized casein kinase I isoform |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YPT7 |
YML001W |
Rab family GTPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YIP3 |
YNL044W |
Protein localized to COPII vesicles |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YPT1 |
YFL038C |
Rab family GTPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YPT31 |
YER031C |
Rab family GTPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
VTI1 |
YMR197C |
Protein involved in cis-Golgi membrane traffic |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
VPS34 |
YLR240W |
Phosphatidylinositol (PI) 3-kinase that synthesizes PI-3-phosphate |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
XRS2 |
YDR369C |
FHA domain-containing component of the Mre11 complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YPC1 |
YBR183W |
Alkaline ceramidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS15 |
YBR097W |
Serine/threonine protein kinase involved in vacuolar protein sorting |
genetic |
1 |
1 |
1 |
Dosage Rescue |
DID2 |
YKR035W-A |
Class E protein of the vacuolar protein-sorting (Vps) pathway |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
STV1 |
YMR054W |
Subunit a of the vacuolar-ATPase V0 domain |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPN4 |
YDL020C |
Transcription factor that stimulates expression of proteasome genes |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SSB2 |
YNL209W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
1 |
1 |
1 |
Co-purification |
COY1 |
YKL179C |
Golgi membrane protein with similarity to mammalian CASP |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
STH1 |
YIL126W |
ATPase component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SRS2 |
YJL092W |
DNA helicase and DNA-dependent ATPase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
DCC1 |
YCL016C |
Subunit of a complex with Ctf8p and Ctf18p |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
TSA1 |
YML028W |
Thioredoxin peroxidase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
PMR1 |
YGL167C |
High affinity Ca2+/Mn2+ P-type ATPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RAD27 |
YKL113C |
5' to 3' exonuclease, 5' flap endonuclease |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SAC1 |
YKL212W |
Phosphatidylinositol phosphate phosphatase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
SLX4 |
YLR135W |
Endonuclease involved in processing DNA |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SDS24 |
YBR214W |
Protein involved in cell separation during budding |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RAD57 |
YDR004W |
Protein that stimulates strand exchange |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SVP26 |
YHR181W |
ER exit adaptor for Golgi mannosyltransferases |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RCR2 |
YDR003W |
Vacuolar ubiquitin ligase-substrate adaptor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PCS60 |
YBR222C |
Oxalyl-CoA synthetase |
physical |
1 |
1 |
1 |
Co-fractionation |
SFT2 |
YBL102W |
Tetra-spanning membrane protein found mostly in the late Golgi |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NEO1 |
YIL048W |
Phospholipid translocase (flippase) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
LGE1 |
YPL055C |
Protein involved in histone H2B ubiquitination |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
SIC1 |
YLR079W |
Cyclin-dependent kinase inhibitor (CKI) |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
VPS24 |
YKL041W |
One of four subunits of the ESCRT-III complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SSP120 |
YLR250W |
Protein packaged into COPII vesicles for ER to Golgi trafficking |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TVP38 |
YKR088C |
Integral membrane protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |