Standard name Systematic name Name description Description
MHF1 YOL086W-A Component of the heterotetrameric MHF histone-fold complex Component of the heterotetrameric MHF histone-fold complex; in humans the MHF complex interacts with both DNA and Mph1p ortholog FANCM, a Fanconi anemia complementation group protein, to stabilize and remodel blocked replication forks and repair damaged DNA; mhf1 srs2 double mutants are MMS hypersensitive; ortholog of human centromere constitutive-associated network (CCAN) subunit CENP-S, also known as MHF1
Visualize the interactome of MHF1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
no data no data no data

GFP localization & abundance

GFP localization GFP abundance
no data no data

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
MHF1 0 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
MPH1 YIR002C 3'-5' DNA helicase involved in error-free bypass of DNA lesions physical 7 4 4 Affinity Capture-Western, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-Western, Two-hybrid, Reconstituted Complex, Affinity Capture-MS
MHF2 YDL160C-A Component of the heterotetrameric MHF histone-fold complex physical 6 4 4 Co-crystal Structure, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
SRS2 YJL092W DNA helicase and DNA-dependent ATPase genetic 4 2 3 Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Rescue
FKH1 YIL131C Forkhead family transcription factor regulation 2 2 2 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation- exonuclease evidence
MPH1 YIR002C 3'-5' DNA helicase involved in error-free bypass of DNA lesions genetic 2 2 2 Synthetic Rescue, Synthetic Growth Defect
SPT2 YER161C Protein involved in negative regulation of transcription regulation 2 1 2 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence
SMC6 YLR383W Subunit of the SMC5-SMC6 complex genetic 2 1 2 Synthetic Rescue, Synthetic Rescue
MTE1 YGR042W Protein of unknown function physical 2 2 1 Affinity Capture-MS, Reconstituted Complex
SMC5 YOL034W Subunit of the SMC5-SMC6 complex physical 2 2 1 Affinity Capture-Western, Reconstituted Complex
FKH2 YNL068C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
AME1 YBR211C Essential kinetochore protein associated with microtubules and SPBs physical 1 1 1 Affinity Capture-MS
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit genetic 1 1 1 Negative Genetic
CDC12 YHR107C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Negative Genetic
DNA2 YHR164C ATP-dependent 5'-flap endonuclease and DNA helicase genetic 1 1 1 Negative Genetic
CMR1 YDL156W Nuclear protein with role in transcription, protein quality control physical 1 1 1 Affinity Capture-MS
MET30 YIL046W F-box protein containing five copies of the WD40 motif genetic 1 1 1 Negative Genetic
ELG1 YOR144C Subunit of an alternative replication factor C complex physical 1 1 1 Two-hybrid
ELG1 YOR144C Subunit of an alternative replication factor C complex genetic 1 1 1 Synthetic Rescue
CNN1 YFR046C Kinetochore protein physical 1 1 1 Affinity Capture-MS
BRL1 YHR036W Essential nuclear envelope/ER integral membrane protein genetic 1 1 1 Negative Genetic
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
SMD1 YGR074W Core Sm protein Sm D1 genetic 1 1 1 Negative Genetic
NOP56 YLR197W Essential evolutionarily-conserved nucleolar protein genetic 1 1 1 Negative Genetic
PFY1 YOR122C Profilin genetic 1 1 1 Negative Genetic