Standard name Systematic name Name description Description
RRP40 YOL142W Exosome non-catalytic core component Exosome non-catalytic core component; involved in 3'-5' RNA processing and degradation in both the nucleus and the cytoplasm; predicted to contain both S1 and KH RNA binding domains; mutations in the human homolog, EXOSC3, cause pontocerebellar hypoplasia with motor neuron degeneration
Visualize the interactome of RRP40
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Nucleolus 0.418 0.425 0.80
Nucleus 0.530 0.447 0.30
Vac/Vac Memb 0.093 0.143 NaN
Bud NaN NaN 0.05
Cytoplasm NaN NaN 0.05
Endosome NaN NaN 0.05

GFP localization & abundance

GFP localization GFP abundance
nucleolus, nucleus 6050

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
RRP40 12 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
RRP6 YOR001W Nuclear exosome exonuclease component physical 12 4 10 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Co-purification, Affinity Capture-MS
DIS3 YOL021C Exosome core complex catalytic subunit physical 11 3 9 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-Western
RRP46 YGR095C Exosome non-catalytic core component physical 9 3 8 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-purification, Affinity Capture-Western, Co-purification
SKI6 YGR195W Exosome non-catalytic core component physical 7 2 5 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western
SKI7 YOR076C GTP-binding protein that couples the Ski complex and exosome physical 6 3 5 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-Western
RRP45 YDR280W Exosome non-catalytic core component physical 6 1 5 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
CSL4 YNL232W Exosome non-catalytic core component physical 5 2 4 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS
FKH1 YIL131C Forkhead family transcription factor regulation 3 2 3 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments
MPP6 YNR024W Nuclear exosome-associated RNA binding protein physical 3 3 2 Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex
RRP4 YHR069C Exosome non-catalytic core component physical 3 1 2 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RRP43 YCR035C Exosome non-catalytic core component physical 3 1 2 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RRP42 YDL111C Exosome non-catalytic core component physical 3 1 2 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
ECM16 YMR128W Essential DEAH-box ATP-dependent RNA helicase specific to U3 snoRNP physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
MTR3 YGR158C Exosome non-catalytic core component physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RFX1 YLR176C Major transcriptional repressor of DNA-damage-regulated genes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
FKH2 YNL068C Forkhead family transcription factor regulation 1 1 1 ChEC-Seq experiments
MED2 YDL005C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
TFC7 YOR110W RNA pol III transcription initiation factor complex (TFIIIC) subunit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MED4 YOR174W Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MED6 YHR058C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
LEU3 YLR451W Zinc-knuckle transcription factor, repressor and activator regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SRB5 YGR104C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
LRP1 YHR081W Nuclear exosome-associated nucleic acid binding protein physical 1 1 1 Affinity Capture-MS
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
UTP10 YJL109C Nucleolar protein physical 1 1 1 Affinity Capture-MS
UTP14 YML093W Subunit of U3-containing Small Subunit (SSU) processome complex physical 1 1 1 Affinity Capture-MS
SLT2 YHR030C Serine/threonine MAP kinase genetic 1 1 1 Synthetic Rescue
OLA1 YBR025C P-loop ATPase with similarity to human OLA1 and bacterial YchF physical 1 1 1 Affinity Capture-MS
ENP1 YBR247C Protein associated with U3 and U14 snoRNAs physical 1 1 1 Affinity Capture-MS
IST1 YNL265C Protein with positive role in the multivesicular body sorting pathway physical 1 1 1 Affinity Capture-MS
KRR1 YCL059C Nucleolar protein required for rRNA synthesis and ribosomal assembly physical 1 1 1 Affinity Capture-MS
NOC4 YPR144C Nucleolar protein physical 1 1 1 Affinity Capture-MS
OSM1 YJR051W Fumarate reductase, catalyzes the reduction of fumarate to succinate physical 1 1 1 Affinity Capture-MS