| Standard name | Systematic name | Name description | Description |
|---|---|---|---|
| NPC2 | YDL046W | Sterol transport protein and functional homolog of human NPC2/He1 | Sterol transport protein and functional homolog of human NPC2/He1; acts with Ncr1p in sterol trafficking; human NPC2 is a cholesterol-binding protein whose deficiency causes Niemann-Pick type C2 disease involving retention of cholesterol in lysosomes; yeast NPC2 can complement mutations in human NPC2 |
Cell cycle phase and timing of transcription peak
| Cell cycle phase | Time (min) |
|---|---|
CYCLoPs localization & abundance
| WT1 | WT2 | WT3 | |
|---|---|---|---|
| Cytoplasm | 0.051 | 0.075 | NaN |
| Endosome | 0.057 | NaN | NaN |
| Mito | 0.166 | 0.133 | NaN |
| Nucleus | 0.261 | 0.183 | 0.463 |
| Vac/Vac Memb | 0.662 | 0.779 | 0.627 |
GFP localization & abundance
| GFP localization | GFP abundance |
|---|---|
| vacuole | 2840 |
GO term count
| Metabolism | Cell cycle | Cell division | Signal transduction | DNA replication | |
|---|---|---|---|---|---|
| NPC2 | 0 | 0 | 0 | 0 | 0 |
List of interactors
Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.| Standard name | Systematic name | Name description | Type | #Experiments | #Methods | #Publications | Evidence |
|---|---|---|---|---|---|---|---|
| MPT5 | YGL178W | mRNA-binding protein of the PUF family | physical | 2 | 1 | 2 | Affinity Capture-RNA, Affinity Capture-RNA |
| IXR1 | YKL032C | Transcriptional repressor that regulates hypoxic genes during normoxia | regulation | 1 | 1 | 1 | DNA to cDNA expression microarray evidence |
| GCR1 | YPL075W | Transcriptional activator of genes involved in glycolysis | regulation | 1 | 1 | 1 | DNA to cDNA expression microarray evidence |
| BUR6 | YER159C | Subunit of a heterodimeric NC2 transcription regulator complex | regulation | 1 | 1 | 1 | chromatin immunoprecipitation-chip evidence |
| MED6 | YHR058C | Subunit of the RNA polymerase II mediator complex | regulation | 1 | 1 | 1 | chromatin immunoprecipitation-chip evidence |
| DHH1 | YDL160C | Cytoplasmic DEAD-box helicase and mRNA decapping activator | physical | 1 | 1 | 1 | Affinity Capture-RNA |
| HEK2 | YBL032W | RNA binding protein involved in asymmetric localization of ASH1 mRNA | physical | 1 | 1 | 1 | Affinity Capture-RNA |
| HHT1 | YBR010W | Histone H3 | physical | 1 | 1 | 1 | Affinity Capture-MS |
| BFR1 | YOR198C | Component of mRNP complexes associated with polyribosomes | physical | 1 | 1 | 1 | Affinity Capture-RNA |
| HHT2 | YNL031C | Histone H3 | physical | 1 | 1 | 1 | Affinity Capture-MS |
| NCR1 | YPL006W | Vacuolar membrane protein involved with Npc2p in sterol trafficking | physical | 1 | 1 | 1 | Reconstituted Complex |
| SLF1 | YDR515W | RNA binding protein that associates with polysomes | physical | 1 | 1 | 1 | Affinity Capture-RNA |
| SRO9 | YCL037C | Cytoplasmic RNA-binding protein | physical | 1 | 1 | 1 | Affinity Capture-RNA |
| PUF3 | YLL013C | Protein of the mitochondrial outer surface | physical | 1 | 1 | 1 | Affinity Capture-RNA |
| PUF2 | YPR042C | PUF family mRNA-binding protein | physical | 1 | 1 | 1 | Affinity Capture-RNA |
| RPS0A | YGR214W | Ribosomal 40S subunit protein S0A | physical | 1 | 1 | 1 | Affinity Capture-MS |
| RPS2 | YGL123W | Protein component of the small (40S) subunit | physical | 1 | 1 | 1 | Affinity Capture-MS |
| RPS6A | YPL090C | Protein component of the small (40S) ribosomal subunit | physical | 1 | 1 | 1 | Affinity Capture-MS |
| RPS10A | YOR293W | Protein component of the small (40S) ribosomal subunit | physical | 1 | 1 | 1 | Affinity Capture-MS |
| RPS12 | YOR369C | Protein component of the small (40S) ribosomal subunit | physical | 1 | 1 | 1 | Affinity Capture-MS |
| RPS15 | YOL040C | Protein component of the small (40S) ribosomal subunit | physical | 1 | 1 | 1 | Affinity Capture-MS |
| RPS17A | YML024W | Ribosomal protein 51 (rp51) of the small (40s) subunit | physical | 1 | 1 | 1 | Affinity Capture-MS |
| RPS19A | YOL121C | Protein component of the small (40S) ribosomal subunit | physical | 1 | 1 | 1 | Affinity Capture-MS |
| RPS20 | YHL015W | Protein component of the small (40S) ribosomal subunit | physical | 1 | 1 | 1 | Affinity Capture-MS |
| RPL25 | YOL127W | Ribosomal 60S subunit protein L25 | physical | 1 | 1 | 1 | Affinity Capture-MS |
| RPS27A | YKL156W | Protein component of the small (40S) ribosomal subunit | physical | 1 | 1 | 1 | Affinity Capture-MS |
| RPL31A | YDL075W | Ribosomal 60S subunit protein L31A | physical | 1 | 1 | 1 | Affinity Capture-MS |
| RPS3 | YNL178W | Protein component of the small (40S) ribosomal subunit | physical | 1 | 1 | 1 | Affinity Capture-MS |
| RPS14A | YCR031C | Protein component of the small (40S) ribosomal subunit | physical | 1 | 1 | 1 | Affinity Capture-MS |
| SSD1 | YDR293C | Translational repressor | physical | 1 | 1 | 1 | Affinity Capture-RNA |
| SCS7 | YMR272C | Sphingolipid alpha-hydroxylase | genetic | 1 | 1 | 1 | Negative Genetic |