ASF1 |
YJL115W |
Nucleosome assembly factor |
physical |
22 |
5 |
21 |
Affinity Capture-Western, Co-purification, Affinity Capture-MS, Co-purification, Co-crystal Structure, Reconstituted Complex, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Reconstituted Complex, Reconstituted Complex |
SIR3 |
YLR442C |
Silencing protein |
physical |
17 |
3 |
14 |
Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Protein-peptide, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Reconstituted Complex |
GCN5 |
YGR252W |
Catalytic subunit of ADA and SAGA histone acetyltransferase complexes |
physical |
16 |
3 |
16 |
Reconstituted Complex, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Affinity Capture-Western, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity |
HHF1 |
YBR009C |
Histone H4 |
physical |
16 |
6 |
15 |
Reconstituted Complex, Affinity Capture-Western, Co-purification, Affinity Capture-MS, Co-localization, Co-localization, Affinity Capture-Western, Co-purification, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, FRET, Reconstituted Complex, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS |
RTT106 |
YNL206C |
Histone chaperone |
physical |
16 |
3 |
12 |
Reconstituted Complex, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex |
RTT109 |
YLL002W |
Histone acetyltransferase |
physical |
14 |
3 |
13 |
Affinity Capture-Western, Biochemical Activity, Biochemical Activity, Biochemical Activity, Reconstituted Complex, Biochemical Activity, Affinity Capture-Western, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity |
ASF1 |
YJL115W |
Nucleosome assembly factor |
genetic |
12 |
4 |
9 |
Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Dosage Growth Defect, Phenotypic Suppression, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Phenotypic Suppression, Negative Genetic, Negative Genetic, Synthetic Growth Defect |
HTA1 |
YDR225W |
Histone H2A |
physical |
10 |
4 |
10 |
Reconstituted Complex, Co-purification, Co-purification, Co-purification, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-MS, Reconstituted Complex, Reconstituted Complex, Affinity Capture-Western |
DOT1 |
YDR440W |
Nucleosomal histone H3-Lys79 methylase |
physical |
10 |
4 |
9 |
Affinity Capture-Western, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Reconstituted Complex, Co-crystal Structure |
SPT16 |
YGL207W |
Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) |
physical |
10 |
4 |
8 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Affinity Capture-MS, Co-localization, Affinity Capture-Western |
HTZ1 |
YOL012C |
Histone variant H2AZ |
physical |
8 |
4 |
8 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-localization, Affinity Capture-MS, FRET, Reconstituted Complex |
RLF2 |
YPR018W |
Largest subunit (p90) of the Chromatin Assembly Complex (CAF-1) |
physical |
8 |
3 |
8 |
Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-Western, Reconstituted Complex |
SPP1 |
YPL138C |
Subunit of COMPASS (Set1C) |
physical |
8 |
5 |
6 |
Protein-peptide, Reconstituted Complex, Affinity Capture-Luminescence, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Co-crystal Structure, Protein-peptide |
YNG1 |
YOR064C |
Subunit of the NuA3 histone acetyltransferase complex |
physical |
8 |
4 |
6 |
Reconstituted Complex, Protein-peptide, Affinity Capture-Western, Affinity Capture-Luminescence, Affinity Capture-Luminescence, Affinity Capture-Western, Protein-peptide, Protein-peptide |
CAC2 |
YML102W |
Subunit of chromatin assembly factor I (CAF-1), with Rlf2p and Msi1p |
physical |
7 |
2 |
7 |
Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western |
GCN5 |
YGR252W |
Catalytic subunit of ADA and SAGA histone acetyltransferase complexes |
genetic |
7 |
3 |
6 |
Synthetic Rescue, Synthetic Rescue, Synthetic Lethality, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Lethality, Synthetic Rescue |
ESA1 |
YOR244W |
Catalytic subunit of the histone acetyltransferase complex (NuA4) |
physical |
6 |
3 |
6 |
Biochemical Activity, Biochemical Activity, Affinity Capture-MS, Reconstituted Complex, Biochemical Activity, Biochemical Activity |
EAF3 |
YPR023C |
Component of the Rpd3S histone deacetylase complex |
physical |
6 |
3 |
6 |
Protein-peptide, Reconstituted Complex, Affinity Capture-MS, Reconstituted Complex, Protein-peptide, Protein-peptide |
HHF2 |
YNL030W |
Histone H4 |
physical |
6 |
3 |
6 |
Co-localization, Co-localization, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western |
SIR2 |
YDL042C |
Conserved NAD+ dependent histone deacetylase of the Sirtuin family |
physical |
6 |
3 |
5 |
Biochemical Activity, Protein-peptide, Biochemical Activity, Affinity Capture-Western, Affinity Capture-Western, Biochemical Activity |
RPD3 |
YNL330C |
Histone deacetylase, component of both the Rpd3S and Rpd3L complexes |
genetic |
6 |
3 |
5 |
Synthetic Rescue, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Rescue, Phenotypic Suppression |
TAF14 |
YPL129W |
Subunit of TFIID, TFIIF, INO80, SWI/SNF, and NuA3 complexes |
physical |
6 |
3 |
5 |
Reconstituted Complex, Affinity Capture-MS, Protein-peptide, Protein-peptide, Reconstituted Complex, Reconstituted Complex |
HIR2 |
YOR038C |
Subunit of HIR nucleosome assembly complex |
genetic |
6 |
1 |
5 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
STH1 |
YIL126W |
ATPase component of the RSC chromatin remodeling complex |
physical |
6 |
5 |
4 |
Affinity Capture-Western, Far Western, Reconstituted Complex, Reconstituted Complex, Co-crystal Structure, Protein-peptide |
YNG2 |
YHR090C |
Subunit of NuA4, an essential histone acetyltransferase complex |
physical |
6 |
4 |
4 |
Affinity Capture-Western, Affinity Capture-Luminescence, Affinity Capture-Luminescence, Affinity Capture-Western, Reconstituted Complex, Protein-peptide |
PHO23 |
YNL097C |
Component of the Rpd3L histone deacetylase complex |
physical |
6 |
3 |
4 |
Affinity Capture-Western, Affinity Capture-Luminescence, Affinity Capture-Luminescence, Affinity Capture-Western, Affinity Capture-Western, Protein-peptide |
RRN5 |
YLR141W |
Protein involved in transcription of rDNA by RNA polymerase I |
physical |
6 |
2 |
4 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western |
EAF1 |
YDR359C |
Component of the NuA4 histone acetyltransferase complex |
physical |
6 |
3 |
3 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Affinity Capture-Western |
RRN9 |
YMR270C |
Protein involved in promoting high level transcription of rDNA |
physical |
6 |
3 |
3 |
Affinity Capture-MS, Co-purification, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western |
HHF1 |
YBR009C |
Histone H4 |
genetic |
5 |
5 |
5 |
Phenotypic Enhancement, Synthetic Rescue, Synthetic Growth Defect, Phenotypic Suppression, Dosage Lethality |
SET2 |
YJL168C |
Histone methyltransferase with a role in transcriptional elongation |
physical |
5 |
4 |
5 |
Co-localization, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Biochemical Activity |
HTB1 |
YDR224C |
Histone H2B |
physical |
5 |
3 |
5 |
Reconstituted Complex, Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex |
POB3 |
YML069W |
Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) |
genetic |
5 |
3 |
5 |
Dosage Lethality, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic |
HHT2 |
YNL031C |
Histone H3 |
physical |
5 |
3 |
5 |
Affinity Capture-MS, Co-localization, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS |
HIF1 |
YLL022C |
Non-essential component of the HAT-B histone acetyltransferase complex |
physical |
5 |
2 |
5 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Reconstituted Complex |
POB3 |
YML069W |
Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) |
physical |
5 |
2 |
5 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western |
SET1 |
YHR119W |
Histone methyltransferase, subunit of the COMPASS (Set1C) complex |
physical |
5 |
1 |
5 |
Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity |
SET2 |
YJL168C |
Histone methyltransferase with a role in transcriptional elongation |
genetic |
5 |
4 |
4 |
Synthetic Growth Defect, Synthetic Growth Defect, Dosage Growth Defect, Synthetic Rescue, Phenotypic Suppression |
CHD1 |
YER164W |
Chromatin remodeler that regulates various aspects of transcription |
physical |
5 |
3 |
4 |
Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Reconstituted Complex, Protein-peptide |
HTA1 |
YDR225W |
Histone H2A |
genetic |
5 |
3 |
4 |
Synthetic Rescue, Positive Genetic, Positive Genetic, Positive Genetic, Synthetic Growth Defect |
PHO23 |
YNL097C |
Component of the Rpd3L histone deacetylase complex |
genetic |
5 |
3 |
4 |
Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Positive Genetic, Negative Genetic |
PDP3 |
YLR455W |
Component of the NuA3b histone acetyltransferase complex |
physical |
5 |
3 |
4 |
Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-MS, Protein-peptide |
YAF9 |
YNL107W |
Subunit of NuA4 histone H4 acetyltransferase and SWR1 complexes |
physical |
5 |
3 |
4 |
Affinity Capture-MS, Reconstituted Complex, Protein-peptide, Reconstituted Complex, Reconstituted Complex |
YTA7 |
YGR270W |
Chromatin-binding ATPase that regulates histone gene expression |
genetic |
5 |
2 |
4 |
Phenotypic Suppression, Positive Genetic, Positive Genetic, Phenotypic Suppression, Positive Genetic |
HHT2 |
YNL031C |
Histone H3 |
genetic |
5 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
ORC1 |
YML065W |
Largest subunit of the origin recognition complex |
physical |
5 |
4 |
3 |
Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Co-crystal Structure, Reconstituted Complex |
RAD53 |
YPL153C |
DNA damage response kinase |
genetic |
5 |
3 |
3 |
Dosage Growth Defect, Dosage Growth Defect, Synthetic Rescue, Synthetic Rescue, Phenotypic Suppression |
RLF2 |
YPR018W |
Largest subunit (p90) of the Chromatin Assembly Complex (CAF-1) |
genetic |
5 |
3 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Phenotypic Enhancement, Synthetic Growth Defect |
RRN10 |
YBL025W |
Protein involved in promoting high level transcription of rDNA |
physical |
5 |
3 |
3 |
Affinity Capture-MS, Co-purification, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS |
CAC2 |
YML102W |
Subunit of chromatin assembly factor I (CAF-1), with Rlf2p and Msi1p |
genetic |
5 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
ISW1 |
YBR245C |
ATPase subunit of imitation-switch (ISWI) class chromatin remodelers |
physical |
4 |
3 |
4 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Reconstituted Complex |
RCO1 |
YMR075W |
Essential component of the Rpd3S histone deacetylase complex |
physical |
4 |
3 |
4 |
Affinity Capture-Western, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-Western |
RPD3 |
YNL330C |
Histone deacetylase, component of both the Rpd3S and Rpd3L complexes |
physical |
4 |
3 |
4 |
Affinity Capture-Western, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS |
SPT10 |
YJL127C |
Histone H3 acetylase with a role in transcriptional regulation |
genetic |
4 |
3 |
4 |
Dosage Rescue, Phenotypic Suppression, Synthetic Lethality, Phenotypic Suppression |
HTA2 |
YBL003C |
Histone H2A |
physical |
4 |
2 |
4 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS |
JHD2 |
YJR119C |
JmjC domain family histone demethylase |
physical |
4 |
2 |
4 |
Biochemical Activity, Biochemical Activity, Biochemical Activity, Affinity Capture-Western |
SPN1 |
YPR133C |
Protein involved in RNA polymerase II transcription |
genetic |
4 |
2 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Rescue |
HIR3 |
YJR140C |
Subunit of the HIR complex |
genetic |
4 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
LSM1 |
YJL124C |
Lsm (Like Sm) protein |
genetic |
4 |
4 |
3 |
Negative Genetic, Dosage Growth Defect, Positive Genetic, Synthetic Rescue |
FPR4 |
YLR449W |
Peptidyl-prolyl cis-trans isomerase (PPIase) |
physical |
4 |
3 |
3 |
Reconstituted Complex, Affinity Capture-MS, Biochemical Activity, Reconstituted Complex |
SIR3 |
YLR442C |
Silencing protein |
genetic |
4 |
3 |
3 |
Phenotypic Suppression, Phenotypic Suppression, Dosage Rescue, Synthetic Rescue |
YTA7 |
YGR270W |
Chromatin-binding ATPase that regulates histone gene expression |
physical |
4 |
3 |
3 |
Reconstituted Complex, Protein-peptide, Affinity Capture-MS, Affinity Capture-MS |
RSC2 |
YLR357W |
Component of the RSC chromatin remodeling complex |
physical |
4 |
3 |
3 |
Reconstituted Complex, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-Western |
SPT6 |
YGR116W |
Nucleosome remodeling protein |
physical |
4 |
3 |
3 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Protein-peptide |
CSE4 |
YKL049C |
Centromeric histone H3-like protein |
genetic |
4 |
3 |
3 |
Dosage Lethality, Phenotypic Suppression, Phenotypic Suppression, Negative Genetic |
CTF18 |
YMR078C |
Subunit of a complex with Ctf8p |
genetic |
4 |
2 |
3 |
Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic |
UAF30 |
YOR295W |
Subunit of UAF (upstream activation factor) complex |
physical |
4 |
2 |
3 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western |
LEO1 |
YOR123C |
Component of the Paf1 complex |
genetic |
4 |
2 |
3 |
Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic |
SOH1 |
YGL127C |
Subunit of the RNA polymerase II mediator complex |
genetic |
4 |
2 |
3 |
Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic |
ARP4 |
YJL081C |
Nuclear actin-related protein involved in chromatin remodeling |
physical |
4 |
3 |
2 |
Far Western, Two-hybrid, Reconstituted Complex, Reconstituted Complex |
MCM2 |
YBL023C |
Protein involved in DNA replication |
physical |
4 |
3 |
2 |
Affinity Capture-Western, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS |
BYE1 |
YKL005C |
Negative regulator of transcription elongation |
physical |
4 |
3 |
2 |
Affinity Capture-Luminescence, Affinity Capture-Luminescence, Affinity Capture-Western, Reconstituted Complex |
CTI6 |
YPL181W |
Component of the Rpd3L histone deacetylase complex |
physical |
4 |
2 |
2 |
Affinity Capture-Luminescence, Affinity Capture-Luminescence, Affinity Capture-Western, Affinity Capture-Western |
ARP8 |
YOR141C |
Nuclear actin-related protein involved in chromatin remodeling |
physical |
3 |
3 |
3 |
Affinity Capture-Western, Protein-peptide, Reconstituted Complex |
CDC6 |
YJL194W |
Essential ATP-binding protein required for DNA replication |
genetic |
3 |
3 |
3 |
Dosage Lethality, Synthetic Growth Defect, Synthetic Rescue |
SPT16 |
YGL207W |
Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) |
genetic |
3 |
3 |
3 |
Dosage Lethality, Synthetic Rescue, Synthetic Lethality |
MSI1 |
YBR195C |
Subunit of chromatin assembly factor I (CAF-1) |
physical |
3 |
3 |
3 |
Affinity Capture-Western, Affinity Capture-MS, Reconstituted Complex |
SPT2 |
YER161C |
Protein involved in negative regulation of transcription |
genetic |
3 |
3 |
3 |
Dosage Rescue, Negative Genetic, Synthetic Lethality |
UBP8 |
YMR223W |
Ubiquitin-specific protease component of the SAGA acetylation complex |
genetic |
3 |
3 |
3 |
Synthetic Growth Defect, Negative Genetic, Synthetic Rescue |
FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
3 |
2 |
3 |
chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments |
FKH2 |
YNL068C |
Forkhead family transcription factor |
regulation |
3 |
2 |
3 |
chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments |
CKA1 |
YIL035C |
Alpha catalytic subunit of casein kinase 2 (CK2) |
physical |
3 |
2 |
3 |
Affinity Capture-MS, Biochemical Activity, Biochemical Activity |
BDF1 |
YLR399C |
BET family transcriptional regulator |
physical |
3 |
2 |
3 |
Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western |
HAT2 |
YEL056W |
Subunit of the Hat1p-Hat2p histone acetyltransferase complex |
physical |
3 |
2 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Protein-peptide |
SIR4 |
YDR227W |
SIR protein involved in assembly of silent chromatin domains |
physical |
3 |
2 |
3 |
Reconstituted Complex, Reconstituted Complex, Affinity Capture-Western |
HIR1 |
YBL008W |
Subunit of the HIR complex |
physical |
3 |
2 |
3 |
Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS |
PSE1 |
YMR308C |
Karyopherin/importin that interacts with the nuclear pore complex |
physical |
3 |
2 |
3 |
Reconstituted Complex, Affinity Capture-MS, Reconstituted Complex |
INO80 |
YGL150C |
Nucleosome spacing factor |
physical |
3 |
2 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex |
RTT106 |
YNL206C |
Histone chaperone |
genetic |
3 |
2 |
3 |
Negative Genetic, Negative Genetic, Synthetic Growth Defect |
SAS3 |
YBL052C |
Histone acetyltransferase catalytic subunit of NuA3 complex |
physical |
3 |
2 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Protein-peptide |
IOC4 |
YMR044W |
Member of a complex (Isw1b) with Isw1p and Ioc2p |
physical |
3 |
2 |
3 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS |
RSC8 |
YFR037C |
Component of the RSC chromatin remodeling complex |
physical |
3 |
2 |
3 |
Affinity Capture-MS, Reconstituted Complex, Affinity Capture-MS |
RTT109 |
YLL002W |
Histone acetyltransferase |
genetic |
3 |
2 |
3 |
Phenotypic Suppression, Synthetic Growth Defect, Synthetic Growth Defect |
SWI3 |
YJL176C |
Subunit of the SWI/SNF chromatin remodeling complex |
physical |
3 |
2 |
3 |
Reconstituted Complex, Reconstituted Complex, Affinity Capture-MS |
RFA1 |
YAR007C |
Subunit of heterotrimeric Replication Protein A (RPA) |
physical |
3 |
2 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western |
UME1 |
YPL139C |
Component of both the Rpd3S and Rpd3L histone deacetylase complexes |
physical |
3 |
2 |
3 |
Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS |
SIN3 |
YOL004W |
Component of both the Rpd3S and Rpd3L histone deacetylase complexes |
physical |
3 |
2 |
3 |
Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS |
HPR1 |
YDR138W |
Subunit of THO/TREX complexes |
genetic |
3 |
2 |
3 |
Synthetic Lethality, Phenotypic Suppression, Phenotypic Suppression |
IPL1 |
YPL209C |
Aurora kinase of chromosomal passenger complex |
physical |
3 |
1 |
3 |
Biochemical Activity, Biochemical Activity, Biochemical Activity |
MCM4 |
YPR019W |
Essential helicase component of heterohexameric MCM2-7 complexes |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
PSH1 |
YOL054W |
E3 ubiquitin ligase targeting centromere-binding protein Cse4p |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
RIF1 |
YBR275C |
Protein involved in control of DNA replication |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
HPC2 |
YBR215W |
Subunit of the HIR complex |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
RSC4 |
YKR008W |
Component of the RSC chromatin remodeling complex |
physical |
3 |
3 |
2 |
Affinity Capture-Western, Co-crystal Structure, Reconstituted Complex |
SGF29 |
YCL010C |
Component of the HAT/Core module of the SAGA, SLIK, and ADA complexes |
physical |
3 |
3 |
2 |
Reconstituted Complex, Co-crystal Structure, Affinity Capture-MS |
RFA2 |
YNL312W |
Subunit of heterotrimeric Replication Protein A (RPA) |
physical |
3 |
3 |
2 |
Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex |
CTF19 |
YPL018W |
Outer kinetochore protein, needed for accurate chromosome segregation |
genetic |
3 |
2 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect, Dosage Lethality |
ESA1 |
YOR244W |
Catalytic subunit of the histone acetyltransferase complex (NuA4) |
genetic |
3 |
2 |
2 |
Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect |
DST1 |
YGL043W |
General transcription elongation factor TFIIS |
genetic |
3 |
2 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Rescue |
HDA1 |
YNL021W |
Catalytic subunit of class II HDA1 histone deacetylase complex |
genetic |
3 |
2 |
2 |
Synthetic Rescue, Synthetic Rescue, Phenotypic Suppression |
CSE2 |
YNR010W |
Subunit of the RNA polymerase II mediator complex |
genetic |
3 |
2 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic |
GIM5 |
YML094W |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
3 |
2 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect, Positive Genetic |
HTB1 |
YDR224C |
Histone H2B |
genetic |
3 |
2 |
2 |
Positive Genetic, Positive Genetic, Synthetic Growth Defect |
KAP123 |
YER110C |
Karyopherin beta |
physical |
3 |
2 |
2 |
Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex |
SET1 |
YHR119W |
Histone methyltransferase, subunit of the COMPASS (Set1C) complex |
genetic |
3 |
2 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect, Phenotypic Enhancement |
SET3 |
YKR029C |
Defining member of the SET3 histone deacetylase complex |
physical |
3 |
2 |
2 |
Affinity Capture-Western, Affinity Capture-Luminescence, Affinity Capture-Western |
RXT2 |
YBR095C |
Component of the histone deacetylase Rpd3L complex |
genetic |
3 |
2 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect, Positive Genetic |
POL1 |
YNL102W |
Catalytic subunit of the DNA polymerase I alpha-primase complex |
physical |
3 |
2 |
2 |
Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS |
MAD2 |
YJL030W |
Component of the spindle-assembly checkpoint complex |
genetic |
3 |
2 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect, Phenotypic Suppression |
MCM16 |
YPR046W |
Component of the Ctf19 complex and the COMA subcomplex |
genetic |
3 |
2 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect, Dosage Lethality |
MCM21 |
YDR318W |
Component of the kinetochore sub-complex COMA |
genetic |
3 |
2 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect, Dosage Lethality |
SPT3 |
YDR392W |
Subunit of the SAGA and SAGA-like transcriptional regulatory complexes |
genetic |
3 |
2 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic |
BUB3 |
YOR026W |
Kinetochore checkpoint WD40 repeat protein |
genetic |
3 |
2 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect, Phenotypic Suppression |
CSE4 |
YKL049C |
Centromeric histone H3-like protein |
physical |
3 |
2 |
2 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western |
BRE1 |
YDL074C |
E3 ubiquitin ligase |
genetic |
3 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect |
ISW1 |
YBR245C |
ATPase subunit of imitation-switch (ISWI) class chromatin remodelers |
genetic |
3 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect |
IKI3 |
YLR384C |
Subunit of Elongator complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
RAD18 |
YCR066W |
E3 ubiquitin ligase |
genetic |
3 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect |
SDS3 |
YIL084C |
Component of the Rpd3L histone deacetylase complex |
genetic |
3 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect |
RPS30A |
YLR287C-A |
Protein component of the small (40S) ribosomal subunit |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
CTF4 |
YPR135W |
Chromatin-associated protein |
genetic |
3 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect |
BMH2 |
YDR099W |
14-3-3 protein, minor isoform |
physical |
3 |
2 |
1 |
Protein-peptide, Protein-peptide, Reconstituted Complex |
JHD1 |
YER051W |
JmjC domain family histone demethylase specific for H3-K36 |
physical |
3 |
2 |
1 |
Affinity Capture-Luminescence, Affinity Capture-Luminescence, Affinity Capture-Western |
GCN5 |
YGR252W |
Catalytic subunit of ADA and SAGA histone acetyltransferase complexes |
regulation |
2 |
2 |
2 |
chromatin immunoprecipitation-qPCR evidence, qualitative western immunoblotting evidence |
STP1 |
YDR463W |
Transcription factor |
regulation |
2 |
2 |
2 |
chromatin immunoprecipitation-chip evidence, DNA to cDNA expression microarray evidence |
SET2 |
YJL168C |
Histone methyltransferase with a role in transcriptional elongation |
regulation |
2 |
2 |
2 |
qualitative western immunoblotting evidence, quantitative western immunoblotting evidence |
NGG1 |
YDR176W |
Subunit of chromatin modifying histone acetyltransferase complexes |
regulation |
2 |
2 |
2 |
DNA to cDNA expression microarray evidence, qualitative western immunoblotting evidence |
CKA2 |
YOR061W |
Alpha' catalytic subunit of casein kinase 2 (CK2) |
physical |
2 |
2 |
2 |
Affinity Capture-MS, Biochemical Activity |
ARP9 |
YMR033W |
Component of both the SWI/SNF and RSC chromatin remodeling complexes |
physical |
2 |
2 |
2 |
Reconstituted Complex, Affinity Capture-MS |
ELP2 |
YGR200C |
Subunit of Elongator complex |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
EPL1 |
YFL024C |
Subunit of NuA4, an essential histone H4/H2A acetyltransferase complex |
physical |
2 |
2 |
2 |
Affinity Capture-Western, Affinity Capture-MS |
ADA2 |
YDR448W |
Transcription coactivator |
physical |
2 |
2 |
2 |
Affinity Capture-MS, Affinity Capture-Western |
FUN30 |
YAL019W |
Snf2p family member with ATP-dependent chromatin remodeling activity |
physical |
2 |
2 |
2 |
Affinity Capture-MS, Reconstituted Complex |
NAP1 |
YKR048C |
Histone chaperone and assembly chaperone for Rps6a/b |
physical |
2 |
2 |
2 |
Affinity Capture-Western, Affinity Capture-MS |
HIR2 |
YOR038C |
Subunit of HIR nucleosome assembly complex |
physical |
2 |
2 |
2 |
Affinity Capture-Western, Affinity Capture-MS |
NHP6A |
YPR052C |
High-mobility group (HMG) protein |
physical |
2 |
2 |
2 |
Affinity Capture-MS, PCA |
SRM1 |
YGL097W |
Nucleotide exchange factor for Gsp1p |
physical |
2 |
2 |
2 |
Affinity Capture-MS, Reconstituted Complex |
VPS75 |
YNL246W |
NAP family histone chaperone |
physical |
2 |
2 |
2 |
Affinity Capture-Western, Reconstituted Complex |
RPH1 |
YER169W |
JmjC domain-containing histone demethylase |
physical |
2 |
2 |
2 |
Biochemical Activity, Protein-peptide |
SNF2 |
YOR290C |
Catalytic subunit of the SWI/SNF chromatin remodeling complex |
physical |
2 |
2 |
2 |
Affinity Capture-Western, Reconstituted Complex |
RSC1 |
YGR056W |
Component of the RSC chromatin remodeling complex |
physical |
2 |
2 |
2 |
Affinity Capture-Western, Reconstituted Complex |
RSC4 |
YKR008W |
Component of the RSC chromatin remodeling complex |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Negative Genetic |
HMT1 |
YBR034C |
Nuclear SAM-dependent mono- and asymmetric methyltransferase |
physical |
2 |
2 |
2 |
Affinity Capture-Western, Biochemical Activity |
NTO1 |
YPR031W |
Subunit of the NuA3 histone acetyltransferase complex |
physical |
2 |
2 |
2 |
Affinity Capture-Western, Protein-peptide |
SGF73 |
YGL066W |
Subunit of DUBm module of SAGA and SLIK |
physical |
2 |
2 |
2 |
Affinity Capture-Western, Affinity Capture-MS |
RGR1 |
YLR071C |
Subunit of the RNA polymerase II mediator complex |
physical |
2 |
2 |
2 |
Reconstituted Complex, Affinity Capture-MS |
RSC58 |
YLR033W |
Component of the RSC chromatin remodeling complex |
physical |
2 |
2 |
2 |
Reconstituted Complex, Affinity Capture-MS |
RSC9 |
YML127W |
Component of the RSC chromatin remodeling complex |
physical |
2 |
2 |
2 |
Reconstituted Complex, Affinity Capture-MS |
RTT102 |
YGR275W |
Component of both the SWI/SNF and RSC chromatin remodeling complexes |
physical |
2 |
2 |
2 |
Reconstituted Complex, Affinity Capture-MS |
SWI1 |
YPL016W |
Subunit of the SWI/SNF chromatin remodeling complex |
physical |
2 |
2 |
2 |
Reconstituted Complex, Affinity Capture-MS |
PUF4 |
YGL014W |
Member of the PUF protein family |
physical |
2 |
2 |
2 |
Affinity Capture-MS, Affinity Capture-RNA |
PUF3 |
YLL013C |
Protein of the mitochondrial outer surface |
physical |
2 |
2 |
2 |
Affinity Capture-MS, Affinity Capture-RNA |
RVB1 |
YDR190C |
ATP-dependent DNA helicase, also known as pontin |
physical |
2 |
2 |
2 |
Affinity Capture-MS, Reconstituted Complex |
PUF2 |
YPR042C |
PUF family mRNA-binding protein |
physical |
2 |
2 |
2 |
Affinity Capture-MS, Affinity Capture-RNA |
IOC3 |
YFR013W |
Subunit of the Isw1a complex |
physical |
2 |
2 |
2 |
Affinity Capture-MS, Reconstituted Complex |
SPT21 |
YMR179W |
Protein with a role in transcriptional silencing |
genetic |
2 |
2 |
2 |
Phenotypic Suppression, Negative Genetic |
SML1 |
YML058W |
Ribonucleotide reductase inhibitor |
genetic |
2 |
2 |
2 |
Dosage Lethality, Synthetic Rescue |
SUB1 |
YMR039C |
Transcriptional regulator |
genetic |
2 |
2 |
2 |
Phenotypic Enhancement, Negative Genetic |
POL30 |
YBR088C |
Proliferating cell nuclear antigen (PCNA) |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
RAD52 |
YML032C |
Protein involved in homologous recombination |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Synthetic Rescue |
RAD50 |
YNL250W |
Subunit of MRX complex with Mre11p and Xrs2p |
genetic |
2 |
2 |
2 |
Synthetic Rescue, Synthetic Growth Defect |
PAF1 |
YBR279W |
Component of the Paf1p complex involved in transcription elongation |
genetic |
2 |
2 |
2 |
Synthetic Rescue, Phenotypic Suppression |
ELP4 |
YPL101W |
Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
SET1 |
YHR119W |
Histone methyltransferase, subunit of the COMPASS (Set1C) complex |
regulation |
2 |
1 |
2 |
qualitative western immunoblotting evidence, qualitative western immunoblotting evidence |
HAT1 |
YPL001W |
Catalytic subunit of the Hat1p-Hat2p histone acetyltransferase complex |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
HAT1 |
YPL001W |
Catalytic subunit of the Hat1p-Hat2p histone acetyltransferase complex |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
2 |
1 |
2 |
Affinity Capture-RNA, Affinity Capture-RNA |
DEP1 |
YAL013W |
Component of the Rpd3L histone deacetylase complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RAD53 |
YPL153C |
DNA damage response kinase |
physical |
2 |
1 |
2 |
Affinity Capture-Western, Affinity Capture-Western |
HTB2 |
YBL002W |
Histone H2B |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
MAM33 |
YIL070C |
Acidic protein of the mitochondrial matrix |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
YKU70 |
YMR284W |
Subunit of the telomeric Ku complex (Yku70p-Yku80p) |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
HSH155 |
YMR288W |
U2-snRNP associated splicing factor |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
RFC5 |
YBR087W |
Subunit of heteropentameric Replication factor C (RF-C) |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
MMS22 |
YLR320W |
Subunit of E3 ubiquitin ligase complex involved in replication repair |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
HST3 |
YOR025W |
Sirtuin, histone H3 deacetylase |
genetic |
2 |
1 |
2 |
Synthetic Rescue, Synthetic Rescue |
RPB10 |
YOR210W |
RNA polymerase subunit ABC10-beta |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
RPC82 |
YPR190C |
RNA polymerase III subunit C82 |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
SIN4 |
YNL236W |
Subunit of the RNA polymerase II mediator complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RPC10 |
YHR143W-A |
RNA polymerase subunit ABC10-alpha, found in RNA pol I, II, and III |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
RPO21 |
YDL140C |
RNA polymerase II largest subunit B220 |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
ISW2 |
YOR304W |
ATP-dependent DNA translocase involved in chromatin remodeling |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
YAF9 |
YNL107W |
Subunit of NuA4 histone H4 acetyltransferase and SWR1 complexes |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
RPB2 |
YOR151C |
RNA polymerase II second largest subunit B150 |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
MPT5 |
YGL178W |
mRNA-binding protein of the PUF family |
physical |
2 |
1 |
2 |
Affinity Capture-RNA, Affinity Capture-RNA |
UBP6 |
YFR010W |
Ubiquitin-specific protease |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SWM1 |
YDR260C |
Subunit of the anaphase-promoting complex (APC) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
STE50 |
YCL032W |
Adaptor protein for various signaling pathways |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
YDR249C |
YDR249C |
Putative protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PIR5 |
YJL160C |
Putative protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SKA1 |
YKL023W |
SKI complex-associated protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SRN2 |
YLR119W |
Component of the ESCRT-I complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
LRS4 |
YDR439W |
Nucleolar protein that forms a complex with Csm1p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PPT2 |
YPL148C |
Phosphopantetheine:protein transferase (PPTase) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SVL3 |
YPL032C |
Protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
HST4 |
YDR191W |
NAD(+)-dependent protein deacetylase |
genetic |
2 |
1 |
2 |
Synthetic Rescue, Synthetic Rescue |
RPA34 |
YJL148W |
RNA polymerase I subunit A34.5 |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RPA14 |
YDR156W |
RNA polymerase I subunit A14 |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SAC3 |
YDR159W |
mRNA export factor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
EIS1 |
YMR031C |
Component of the eisosome required for proper eisosome assembly |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
ELF1 |
YKL160W |
Transcription elongation factor with a conserved zinc finger domain |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
NHP6B |
YBR089C-A |
High-mobility group (HMG) protein |
physical |
2 |
2 |
1 |
PCA, Reconstituted Complex |
SWD2 |
YKL018W |
Subunit of the COMPASS (Set1C) histone H3K4 methyltransferase complex |
physical |
2 |
2 |
1 |
Co-localization, Protein-peptide |
PAT1 |
YCR077C |
Deadenylation-dependent mRNA-decapping factor |
genetic |
2 |
2 |
1 |
Positive Genetic, Synthetic Rescue |
SGO1 |
YOR073W |
Component of the spindle checkpoint |
physical |
2 |
2 |
1 |
Affinity Capture-Western, Reconstituted Complex |
CTR1 |
YPR124W |
High-affinity copper transporter of plasma membrane |
genetic |
2 |
2 |
1 |
Phenotypic Enhancement, Synthetic Growth Defect |
CDC73 |
YLR418C |
Component of the Paf1p complex |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
ARP4 |
YJL081C |
Nuclear actin-related protein involved in chromatin remodeling |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
EAF1 |
YDR359C |
Component of the NuA4 histone acetyltransferase complex |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
EAF5 |
YEL018W |
Non-essential subunit of the NuA4 acetyltransferase complex |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
BMH1 |
YER177W |
14-3-3 protein, major isoform |
physical |
2 |
1 |
1 |
Protein-peptide, Protein-peptide |
DPB3 |
YBR278W |
Third-largest subunit of DNA polymerase II (DNA polymerase epsilon) |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
EAF3 |
YPR023C |
Component of the Rpd3S histone deacetylase complex |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
EPL1 |
YFL024C |
Subunit of NuA4, an essential histone H4/H2A acetyltransferase complex |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
ADA2 |
YDR448W |
Transcription coactivator |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
HDA3 |
YPR179C |
Subunit of HDA1 histone deacetylase complex |
genetic |
2 |
1 |
1 |
Synthetic Rescue, Synthetic Rescue |
HDA2 |
YDR295C |
Subunit of HDA1 histone deacetylase complex |
genetic |
2 |
1 |
1 |
Synthetic Rescue, Synthetic Rescue |
GIM3 |
YNL153C |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
CTI6 |
YPL181W |
Component of the Rpd3L histone deacetylase complex |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
BRE2 |
YLR015W |
Subunit of COMPASS (Set1C) complex |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
ACS2 |
YLR153C |
Acetyl-coA synthetase isoform |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
CIN8 |
YEL061C |
Bipolar kinesin motor protein |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
SAS3 |
YBL052C |
Histone acetyltransferase catalytic subunit of NuA3 complex |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
MMS22 |
YLR320W |
Subunit of E3 ubiquitin ligase complex involved in replication repair |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
SNF2 |
YOR290C |
Catalytic subunit of the SWI/SNF chromatin remodeling complex |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
RSC1 |
YGR056W |
Component of the RSC chromatin remodeling complex |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
SPT7 |
YBR081C |
Subunit of the SAGA transcriptional regulatory complex |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
SPP1 |
YPL138C |
Subunit of COMPASS (Set1C) |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
SET3 |
YKR029C |
Defining member of the SET3 histone deacetylase complex |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
HOS2 |
YGL194C |
Histone deacetylase and subunit of Set3 and Rpd3L complexes |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
YNG2 |
YHR090C |
Subunit of NuA4, an essential histone acetyltransferase complex |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
SWD1 |
YAR003W |
Subunit of the COMPASS (Set1C) complex |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
SWD3 |
YBR175W |
Essential subunit of the COMPASS (Set1C) complex |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
RGR1 |
YLR071C |
Subunit of the RNA polymerase II mediator complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
SIN3 |
YOL004W |
Component of both the Rpd3S and Rpd3L histone deacetylase complexes |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
SDC1 |
YDR469W |
Subunit of the COMPASS (Set1C) complex |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
SWC4 |
YGR002C |
Component of the Swr1p complex that incorporates Htz1p into chromatin |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
RFC1 |
YOR217W |
Subunit of heteropentameric Replication factor C (RF-C) |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
MRC1 |
YCL061C |
S-phase checkpoint protein required for DNA replication |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
SIF2 |
YBR103W |
WD40 repeat-containing subunit of Set3C histone deacetylase complex |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
NGG1 |
YDR176W |
Subunit of chromatin modifying histone acetyltransferase complexes |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
IES6 |
YEL044W |
Component of the INO80 chromatin remodeling complex |
physical |
2 |
1 |
1 |
Reconstituted Complex, Reconstituted Complex |
RVB2 |
YPL235W |
ATP-dependent DNA helicase, also known as reptin |
physical |
2 |
1 |
1 |
Reconstituted Complex, Reconstituted Complex |
HOS4 |
YIL112W |
Subunit of the Set3 complex |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
IES3 |
YLR052W |
Subunit of the INO80 chromatin remodeling complex |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
LGE1 |
YPL055C |
Protein involved in histone H2B ubiquitination |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
MIF2 |
YKL089W |
Centromeric CDEIII region binding protein |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
MMS1 |
YPR164W |
Subunit of E3 ubiquitin ligase complex involved in replication repair |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
PFD1 |
YJL179W |
Subunit of heterohexameric prefoldin |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
POL32 |
YJR043C |
Third subunit of DNA polymerase delta |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
RAD27 |
YKL113C |
5' to 3' exonuclease, 5' flap endonuclease |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
RAD6 |
YGL058W |
Ubiquitin-conjugating enzyme (E2) |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
RIC1 |
YLR039C |
Protein involved in retrograde transport to the cis-Golgi network |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
RTF1 |
YGL244W |
Subunit of RNAPII-associated chromatin remodeling Paf1 complex |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
SAP30 |
YMR263W |
Component of Rpd3L histone deacetylase complex |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
SNT1 |
YCR033W |
Set3C histone deacetylase scaffold |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
SPT8 |
YLR055C |
Subunit of the SAGA transcriptional regulatory complex |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
SRB2 |
YHR041C |
Subunit of the RNA polymerase II mediator complex |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
TOF1 |
YNL273W |
Subunit of a replication-pausing checkpoint complex |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
TUB3 |
YML124C |
Alpha-tubulin |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
UME6 |
YDR207C |
Rpd3L histone deacetylase complex subunit |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
YKE2 |
YLR200W |
Subunit of the heterohexameric Gim/prefoldin protein complex |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
UBA4 |
YHR111W |
E1-like protein that activates Urm1p before urmylation |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
DIA2 |
YOR080W |
Origin-binding F-box protein |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
CLB2 |
YPR119W |
B-type cyclin involved in cell cycle progression |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
BRE5 |
YNR051C |
Ubiquitin protease cofactor |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
CTF8 |
YHR191C |
Subunit of a complex with Ctf18p |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
GIM4 |
YEL003W |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
CIN1 |
YOR349W |
Tubulin folding factor D involved in beta-tubulin (Tub2p) folding |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
CIN2 |
YPL241C |
GTPase-activating protein (GAP) for Cin4p |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
EAF7 |
YNL136W |
Subunit of the NuA4 histone acetyltransferase complex |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
DCC1 |
YCL016C |
Subunit of a complex with Ctf8p and Ctf18p |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
SPT10 |
YJL127C |
Histone H3 acetylase with a role in transcriptional regulation |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
GCR1 |
YPL075W |
Transcriptional activator of genes involved in glycolysis |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
SPT20 |
YOL148C |
Subunit of the SAGA transcriptional regulatory complex |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
XBP1 |
YIL101C |
Transcriptional repressor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
BUR6 |
YER159C |
Subunit of a heterodimeric NC2 transcription regulator complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
YAP6 |
YDR259C |
Basic leucine zipper (bZIP) transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
HSF1 |
YGL073W |
Trimeric heat shock transcription factor |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
BAS1 |
YKR099W |
Myb-related transcription factor |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
CST6 |
YIL036W |
Basic leucine zipper (bZIP) transcription factor from ATF/CREB family |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
SIN3 |
YOL004W |
Component of both the Rpd3S and Rpd3L histone deacetylase complexes |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
SOK2 |
YMR016C |
Nuclear protein that negatively regulates pseudohyphal differentiation |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
RPH1 |
YER169W |
JmjC domain-containing histone demethylase |
regulation |
1 |
1 |
1 |
quantitative western immunoblotting evidence |
NHP6A |
YPR052C |
High-mobility group (HMG) protein |
regulation |
1 |
1 |
1 |
quantitative reverse transcription polymerase chain reaction evidence |
OAF1 |
YAL051W |
Oleate-activated transcription factor |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
SCH9 |
YHR205W |
AGC family protein kinase |
regulation |
1 |
1 |
1 |
qualitative western immunoblotting evidence |
NHP6B |
YBR089C-A |
High-mobility group (HMG) protein |
regulation |
1 |
1 |
1 |
quantitative reverse transcription polymerase chain reaction evidence |
YTA7 |
YGR270W |
Chromatin-binding ATPase that regulates histone gene expression |
regulation |
1 |
1 |
1 |
quantitative polymerase chain reaction evidence |
CKA1 |
YIL035C |
Alpha catalytic subunit of casein kinase 2 (CK2) |
regulation |
1 |
1 |
1 |
qualitative western immunoblotting evidence |
HHT2 |
YNL031C |
Histone H3 |
regulation |
1 |
1 |
1 |
quantitative western immunoblotting evidence |
CHD1 |
YER164W |
Chromatin remodeler that regulates various aspects of transcription |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CWC25 |
YNL245C |
Splicing factor required for the first step of pre-mRNA splicing |
genetic |
1 |
1 |
1 |
Negative Genetic |
AME1 |
YBR211C |
Essential kinetochore protein associated with microtubules and SPBs |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
AME1 |
YBR211C |
Essential kinetochore protein associated with microtubules and SPBs |
genetic |
1 |
1 |
1 |
Dosage Lethality |
CTF3 |
YLR381W |
Outer kinetochore protein that forms a complex with Mcm16p and Mcm22p |
genetic |
1 |
1 |
1 |
Dosage Lethality |
DSN1 |
YIR010W |
Essential component of the outer kinetochore MIND complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CBF5 |
YLR175W |
Pseudouridine synthase catalytic subunit of box H/ACA snoRNPs |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CBF5 |
YLR175W |
Pseudouridine synthase catalytic subunit of box H/ACA snoRNPs |
genetic |
1 |
1 |
1 |
Positive Genetic |
ENP2 |
YGR145W |
Component of the SSU |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BRX1 |
YOL077C |
Nucleolar protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DBP9 |
YLR276C |
DEAD-box protein required for 27S rRNA processing |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DRS1 |
YLL008W |
Nucleolar DEAD-box protein required for ribosome assembly and function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DRS1 |
YLL008W |
Nucleolar DEAD-box protein required for ribosome assembly and function |
genetic |
1 |
1 |
1 |
Negative Genetic |
EBP2 |
YKL172W |
Required for 25S rRNA maturation and 60S ribosomal subunit assembly |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HAS1 |
YMR290C |
ATP-dependent RNA helicase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GCD6 |
YDR211W |
Catalytic epsilon subunit of the translation initiation factor eIF2B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ARC1 |
YGL105W |
Protein that binds tRNA and methionyl- and glutamyl-tRNA synthetases |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DBP7 |
YKR024C |
Putative ATP-dependent RNA helicase of the DEAD-box family |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CDC33 |
YOL139C |
Translation initiation factor eIF4E |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CDC48 |
YDL126C |
AAA ATPase with protein-unfoldase activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
CSL4 |
YNL232W |
Exosome non-catalytic core component |
genetic |
1 |
1 |
1 |
Negative Genetic |
GCD11 |
YER025W |
Gamma subunit of the translation initiation factor eIF2 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ARP7 |
YPR034W |
Component of both the SWI/SNF and RSC chromatin remodeling complexes |
physical |
1 |
1 |
1 |
Reconstituted Complex |
GCD1 |
YOR260W |
Gamma subunit of the translation initiation factor eIF2B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
CDC39 |
YCR093W |
Subunit of the CCR4-NOT1 core complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BMS1 |
YPL217C |
GTPase required for ribosomal subunit synthesis and rRNA processing |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ACC1 |
YNR016C |
Acetyl-CoA carboxylase, biotin containing enzyme |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ADE4 |
YMR300C |
Phosphoribosylpyrophosphate amidotransferase (PRPPAT) |
genetic |
1 |
1 |
1 |
Positive Genetic |
APL3 |
YBL037W |
Alpha-adaptin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ARP2 |
YDL029W |
Essential component of the Arp2/3 complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ARP3 |
YJR065C |
Essential component of the Arp2/3 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
BET3 |
YKR068C |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
1 |
1 |
1 |
Negative Genetic |
ASC1 |
YMR116C |
G-protein beta subunit and guanine dissociation inhibitor for Gpa2p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BEM2 |
YER155C |
Rho GTPase activating protein (RhoGAP) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CDC14 |
YFR028C |
Protein phosphatase required for mitotic exit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BOI2 |
YER114C |
Protein involved in polar growth |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CDC28 |
YBR160W |
Cyclin-dependent kinase (CDK) catalytic subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CDC11 |
YJR076C |
Component of the septin ring that is required for cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC3 |
YLR314C |
Component of the septin ring that is required for cytokinesis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BNI1 |
YNL271C |
Formin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HDA1 |
YNL021W |
Catalytic subunit of class II HDA1 histone deacetylase complex |
physical |
1 |
1 |
1 |
Reconstituted Complex |
CEG1 |
YGL130W |
Guanylyltransferase involved in mRNA 5' capping |
genetic |
1 |
1 |
1 |
Negative Genetic |
CHC1 |
YGL206C |
Clathrin heavy chain |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CIP1 |
YPL014W |
Cyclin-dependent kinase inhibitor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CTF18 |
YMR078C |
Subunit of a complex with Ctf8p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CTK1 |
YKL139W |
Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) |
physical |
1 |
1 |
1 |
Co-localization |
CYR1 |
YJL005W |
Adenylate cyclase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DOA1 |
YKL213C |
WD-repeat protein involved in ubiquitin-mediated protein degradation |
genetic |
1 |
1 |
1 |
Negative Genetic |
EXO84 |
YBR102C |
Exocyst subunit with dual roles in exocytosis and spliceosome assembly |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
FIP1 |
YJR093C |
Subunit of cleavage polyadenylation factor (CPF) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
FKS1 |
YLR342W |
Catalytic subunit of 1,3-beta-D-glucan synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GGA2 |
YHR108W |
Protein that regulates Arf1p, Arf2p to facilitate Golgi trafficking |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HAT2 |
YEL056W |
Subunit of the Hat1p-Hat2p histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
ECM5 |
YMR176W |
Subunit of the Snt2C complex |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
HHF2 |
YNL030W |
Histone H4 |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
DPB4 |
YDR121W |
Subunit of DNA pol epsilon and of ISW2 chromatin accessibility complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CLU1 |
YMR012W |
Subunit of the eukaryotic translation initiation factor 3 (eIF3) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ECM29 |
YHL030W |
Scaffold protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
END3 |
YNL084C |
EH domain-containing protein involved in endocytosis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GFA1 |
YKL104C |
Glutamine-fructose-6-phosphate amidotransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GLT1 |
YDL171C |
NAD(+)-dependent glutamate synthase (GOGAT) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
FAB1 |
YFR019W |
1-phosphatidylinositol-3-phosphate 5-kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ATG26 |
YLR189C |
UDP-glucose:sterol glucosyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CMR1 |
YDL156W |
Nuclear protein with role in transcription, protein quality control |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CMR1 |
YDL156W |
Nuclear protein with role in transcription, protein quality control |
genetic |
1 |
1 |
1 |
Positive Genetic |
GIN4 |
YDR507C |
Protein kinase involved in bud growth and assembly of the septin ring |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DIG1 |
YPL049C |
MAP kinase-responsive inhibitor of the Ste12p transcription factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DBP8 |
YHR169W |
ATPase, putative RNA helicase of the DEAD-box family |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GCN20 |
YFR009W |
Positive regulator of the Gcn2p kinase activity |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DEP1 |
YAL013W |
Component of the Rpd3L histone deacetylase complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DBP2 |
YNL112W |
ATP-dependent RNA helicase of the DEAD-box protein family |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CSI1 |
YMR025W |
Subunit of the Cop9 signalosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
ABF2 |
YMR072W |
Mitochondrial DNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CCT2 |
YIL142W |
Subunit beta of the cytosolic chaperonin Cct ring complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DAL3 |
YIR032C |
Ureidoglycolate lyase |
genetic |
1 |
1 |
1 |
Negative Genetic |
BCK1 |
YJL095W |
MAPKKK acting in the protein kinase C signaling pathway |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ECM30 |
YLR436C |
Protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BRO1 |
YPL084W |
Cytoplasmic class E vacuolar protein sorting (VPS) factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BRO1 |
YPL084W |
Cytoplasmic class E vacuolar protein sorting (VPS) factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
HEK2 |
YBL032W |
RNA binding protein involved in asymmetric localization of ASH1 mRNA |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BOI1 |
YBL085W |
Protein involved in polar growth, functionally redundant with Boi2p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DIM1 |
YPL266W |
Essential 18S rRNA dimethylase (dimethyladenosine transferase) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
EDC3 |
YEL015W |
Non-essential conserved protein with a role in mRNA decapping |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DNM1 |
YLL001W |
Dynamin-related GTPase involved in mitochondrial organization |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
AKL1 |
YBR059C |
Ser/Thr protein kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ADR1 |
YDR216W |
Carbon source-responsive zinc-finger transcription factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CAF20 |
YOR276W |
Phosphoprotein of the mRNA cap-binding complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CDC53 |
YDL132W |
Cullin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
FAA4 |
YMR246W |
Long chain fatty acyl-CoA synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
APM3 |
YBR288C |
Mu3-like subunit of the clathrin associated protein complex (AP-3) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GLC8 |
YMR311C |
Regulatory subunit of protein phosphatase 1 (Glc7p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
CHK1 |
YBR274W |
Serine/threonine kinase and DNA damage checkpoint effector |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CCT5 |
YJR064W |
Subunit of the cytosolic chaperonin Cct ring complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ENV7 |
YPL236C |
Vacuolar membrane protein kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
GPD1 |
YDL022W |
NAD-dependent glycerol-3-phosphate dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ATG12 |
YBR217W |
Ubiquitin-like modifier involved in autophagy and the Cvt pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
CBK1 |
YNL161W |
Serine/threonine protein kinase of the the RAM signaling network |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ACS2 |
YLR153C |
Acetyl-coA synthetase isoform |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CDC20 |
YGL116W |
Activator of anaphase-promoting complex/cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
CCT3 |
YJL014W |
Subunit of the cytosolic chaperonin Cct ring complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CCT3 |
YJL014W |
Subunit of the cytosolic chaperonin Cct ring complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
GIP2 |
YER054C |
Putative regulatory subunit of protein phosphatase Glc7p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
FHL1 |
YPR104C |
Regulator of ribosomal protein (RP) transcription |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
APE1 |
YKL103C |
Vacuolar aminopeptidase yscI |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BEM3 |
YPL115C |
Rho GTPase activating protein (RhoGAP) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CIN8 |
YEL061C |
Bipolar kinesin motor protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
FAA1 |
YOR317W |
Long chain fatty acyl-CoA synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MAG1 |
YER142C |
3-methyl-adenine DNA glycosylase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MGT1 |
YDL200C |
DNA repair methyltransferase (6-O-methylguanine-DNA methylase) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SUS1 |
YBR111W-A |
Global transcriptional regulator, component of SAGA, TREX-2 complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TAF6 |
YGL112C |
Subunit (60 kDa) of TFIID and SAGA complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TUP1 |
YCR084C |
General repressor of transcription in complex with Cyc8p |
physical |
1 |
1 |
1 |
Reconstituted Complex |
TUP1 |
YCR084C |
General repressor of transcription in complex with Cyc8p |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
HIR1 |
YBL008W |
Subunit of the HIR complex |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
KAP123 |
YER110C |
Karyopherin beta |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SNF1 |
YDR477W |
AMP-activated S/T protein kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
SIR2 |
YDL042C |
Conserved NAD+ dependent histone deacetylase of the Sirtuin family |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
RTG3 |
YBL103C |
bHLH/Zip transcription factor for retrograde (RTG) and TOR pathways |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HMO1 |
YDR174W |
Chromatin associated high mobility group (HMG) family member |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SLX9 |
YGR081C |
Protein required for pre-rRNA processing |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HIF1 |
YLL022C |
Non-essential component of the HAT-B histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
VAC7 |
YNL054W |
Integral vacuolar membrane protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SKO1 |
YNL167C |
Basic leucine zipper transcription factor of the ATF/CREB family |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NHP6A |
YPR052C |
High-mobility group (HMG) protein |
genetic |
1 |
1 |
1 |
Dosage Lethality |
YCR087C-A |
YCR087C-A |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
STP1 |
YDR463W |
Transcription factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SCC4 |
YER147C |
Subunit of cohesin loading factor (Scc2p-Scc4p) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PHO4 |
YFR034C |
Basic helix-loop-helix (bHLH) transcription factor of the myc-family |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MIG1 |
YGL035C |
Transcription factor involved in glucose repression |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MIG1 |
YGL035C |
Transcription factor involved in glucose repression |
genetic |
1 |
1 |
1 |
Negative Genetic |
RTT101 |
YJL047C |
Cullin subunit of a Roc1p-dependent E3 ubiquitin ligase complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
KAP104 |
YBR017C |
Transportin or cytosolic karyopherin beta 2 |
physical |
1 |
1 |
1 |
Reconstituted Complex |
RPH1 |
YER169W |
JmjC domain-containing histone demethylase |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
RAD54 |
YGL163C |
DNA-dependent ATPase that stimulates strand exchange |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
RAD54 |
YGL163C |
DNA-dependent ATPase that stimulates strand exchange |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
JHD2 |
YJR119C |
JmjC domain family histone demethylase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
SPT7 |
YBR081C |
Subunit of the SAGA transcriptional regulatory complex |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
PUB1 |
YNL016W |
Poly (A)+ RNA-binding protein |
physical |
1 |
1 |
1 |
Two-hybrid |
YBP2 |
YGL060W |
Central kinetochore associated protein |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
HST3 |
YOR025W |
Sirtuin, histone H3 deacetylase |
physical |
1 |
1 |
1 |
Biochemical Activity |
ORC2 |
YBR060C |
Subunit of the origin recognition complex (ORC) |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
ORC3 |
YLL004W |
Subunit of the origin recognition complex (ORC) |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
HOS3 |
YPL116W |
Trichostatin A-insensitive homodimeric histone deacetylase (HDAC) |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
HOS2 |
YGL194C |
Histone deacetylase and subunit of Set3 and Rpd3L complexes |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
TOP1 |
YOL006C |
Topoisomerase I |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
SNT2 |
YGL131C |
Subunit of Snt2C complex, RING finger ubiquitin ligase (E3) |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
RCO1 |
YMR075W |
Essential component of the Rpd3S histone deacetylase complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
NAB2 |
YGL122C |
Nuclear polyadenylated RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
RFA1 |
YAR007C |
Subunit of heterotrimeric Replication Protein A (RPA) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SWD1 |
YAR003W |
Subunit of the COMPASS (Set1C) complex |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
SWD3 |
YBR175W |
Essential subunit of the COMPASS (Set1C) complex |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
STE7 |
YDL159W |
Signal transducing MAP kinase kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SGF29 |
YCL010C |
Component of the HAT/Core module of the SAGA, SLIK, and ADA complexes |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPF2 |
YKR081C |
Essential protein involved in rRNA maturation and ribosomal assembly |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MED8 |
YBR193C |
Subunit of the RNA polymerase II mediator complex |
physical |
1 |
1 |
1 |
Reconstituted Complex |
MED1 |
YPR070W |
Subunit of the RNA polymerase II mediator complex |
physical |
1 |
1 |
1 |
Reconstituted Complex |
SRB5 |
YGR104C |
Subunit of the RNA polymerase II mediator complex |
physical |
1 |
1 |
1 |
Reconstituted Complex |
HTL1 |
YCR020W-B |
Component of the RSC chromatin remodeling complex |
physical |
1 |
1 |
1 |
Reconstituted Complex |
LDB7 |
YBL006C |
Component of the RSC chromatin remodeling complex |
physical |
1 |
1 |
1 |
Reconstituted Complex |
NPL6 |
YMR091C |
Component of the RSC chromatin remodeling complex |
physical |
1 |
1 |
1 |
Reconstituted Complex |
RSC3 |
YDR303C |
Component of the RSC chromatin remodeling complex |
physical |
1 |
1 |
1 |
Reconstituted Complex |
RSC30 |
YHR056C |
Component of the RSC chromatin remodeling complex |
physical |
1 |
1 |
1 |
Reconstituted Complex |
RSC6 |
YCR052W |
Component of the RSC chromatin remodeling complex |
physical |
1 |
1 |
1 |
Reconstituted Complex |
SFH1 |
YLR321C |
Component of the RSC chromatin remodeling complex |
physical |
1 |
1 |
1 |
Reconstituted Complex |
SNF11 |
YDR073W |
Subunit of the SWI/SNF chromatin remodeling complex |
physical |
1 |
1 |
1 |
Reconstituted Complex |
SNF12 |
YNR023W |
73 kDa subunit of the SWI/SNF chromatin remodeling complex |
physical |
1 |
1 |
1 |
Reconstituted Complex |
SNF5 |
YBR289W |
Subunit of the SWI/SNF chromatin remodeling complex |
physical |
1 |
1 |
1 |
Reconstituted Complex |
SNF6 |
YHL025W |
Subunit of the SWI/SNF chromatin remodeling complex |
physical |
1 |
1 |
1 |
Reconstituted Complex |
SWP82 |
YFL049W |
Member of the SWI/SNF chromatin remodeling complex |
physical |
1 |
1 |
1 |
Reconstituted Complex |
RIM1 |
YCR028C-A |
ssDNA-binding protein essential for mitochondrial genome maintenance |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RFA3 |
YJL173C |
Subunit of heterotrimeric Replication Protein A (RPA) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YKU80 |
YMR106C |
Subunit of telomeric Ku complex (Yku70p-Yku80p) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPB10 |
YOR210W |
RNA polymerase subunit ABC10-beta |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPC17 |
YJL011C |
RNA polymerase III subunit C17 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPO31 |
YOR116C |
RNA polymerase III largest subunit C160 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPC53 |
YDL150W |
RNA polymerase III subunit C53 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
VPS60 |
YDR486C |
Protein involved in late endosome to vacuole transport |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MOT3 |
YMR070W |
Transcriptional repressor, activator |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPC31 |
YNL151C |
RNA polymerase III subunit C31 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPC37 |
YKR025W |
RNA polymerase III subunit C37 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPC40 |
YPR110C |
RNA polymerase subunit AC40 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YMR315W |
YMR315W |
Protein with NADP(H) oxidoreductase activity |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YMR315W |
YMR315W |
Protein with NADP(H) oxidoreductase activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
PHO2 |
YDL106C |
Homeobox transcription factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SAC7 |
YDR389W |
GTPase activating protein (GAP) for Rho1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TOP3 |
YLR234W |
DNA Topoisomerase III |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SIN4 |
YNL236W |
Subunit of the RNA polymerase II mediator complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PAN1 |
YIR006C |
Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SDC1 |
YDR469W |
Subunit of the COMPASS (Set1C) complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPT3 |
YDR394W |
ATPase of the 19S regulatory particle of the 26S proteasome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RRN9 |
YMR270C |
Protein involved in promoting high level transcription of rDNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
OKP1 |
YGR179C |
Outer kinetochore protein required for accurate chromosome segregation |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
OKP1 |
YGR179C |
Outer kinetochore protein required for accurate chromosome segregation |
genetic |
1 |
1 |
1 |
Dosage Lethality |
RPT1 |
YKL145W |
ATPase of the 19S regulatory particle of the 26S proteasome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TAF4 |
YMR005W |
TFIID subunit (48 kDa) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
IDH1 |
YNL037C |
Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RVS161 |
YCR009C |
Amphiphysin-like lipid raft protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RVS161 |
YCR009C |
Amphiphysin-like lipid raft protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRPL36 |
YBR122C |
Mitochondrial ribosomal protein of the large subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PRE6 |
YOL038W |
Alpha 4 subunit of the 20S proteasome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MYO2 |
YOR326W |
Type V myosin motor involved in actin-based transport of cargos |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YME2 |
YMR302C |
Integral inner mitochondrial membrane protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ICS2 |
YBR157C |
Protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SUP35 |
YDR172W |
Translation termination factor eRF3 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
IFA38 |
YBR159W |
Microsomal beta-keto-reductase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RLP24 |
YLR009W |
Essential protein required for ribosomal large subunit biogenesis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SWC4 |
YGR002C |
Component of the Swr1p complex that incorporates Htz1p into chromatin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MSN4 |
YKL062W |
Stress-responsive transcriptional activator |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MAE1 |
YKL029C |
Mitochondrial malic enzyme |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PNO1 |
YOR145C |
Essential nucleolar protein required for pre-18S rRNA processing |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
KRI1 |
YNL308C |
Essential nucleolar protein required for 40S ribosome biogenesis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TAF9 |
YMR236W |
Subunit (17 kDa) of TFIID and SAGA complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NPC2 |
YDL046W |
Sterol transport protein and functional homolog of human NPC2/He1 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MRPL35 |
YDR322W |
Mitochondrial ribosomal protein of the large subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MRPL35 |
YDR322W |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRP7 |
YNL005C |
Mitochondrial ribosomal protein of the large subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SDA1 |
YGR245C |
Protein required for actin organization and passage through Start |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YKT6 |
YKL196C |
Vesicle membrane protein (v-SNARE) with acyltransferase activity |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SAN1 |
YDR143C |
Ubiquitin-protein ligase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MRM1 |
YOR201C |
Ribose methyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PRE5 |
YMR314W |
Alpha 6 subunit of the 20S proteasome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
UTP20 |
YBL004W |
Component of the small-subunit (SSU) processome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MAK21 |
YDR060W |
Constituent of 66S pre-ribosomal particles |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
KRR1 |
YCL059C |
Nucleolar protein required for rRNA synthesis and ribosomal assembly |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RFC4 |
YOL094C |
Subunit of heteropentameric Replication factor C (RF-C) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
LSC1 |
YOR142W |
Alpha subunit of succinyl-CoA ligase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPN1 |
YHR027C |
Non-ATPase base subunit of the 19S RP of the 26S proteasome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YPK1 |
YKL126W |
S/T protein kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RIX1 |
YHR197W |
Component of the Rix1 complex and possibly pre-replicative complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MAK5 |
YBR142W |
Essential nucleolar protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SER1 |
YOR184W |
3-phosphoserine aminotransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YPL150W |
YPL150W |
Protein kinase of unknown cellular role |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SSF1 |
YHR066W |
Constituent of 66S pre-ribosomal particles |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NOC4 |
YPR144C |
Nucleolar protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
UTP7 |
YER082C |
Nucleolar protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
UTP7 |
YER082C |
Nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
TRA1 |
YHR099W |
Subunit of SAGA and NuA4 histone acetyltransferase complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PIB2 |
YGL023C |
Phosphatidylinositol 3-phosphate binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RFC1 |
YOR217W |
Subunit of heteropentameric Replication factor C (RF-C) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MRC1 |
YCL061C |
S-phase checkpoint protein required for DNA replication |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPA135 |
YPR010C |
RNA polymerase I second largest subunit A135 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TOP2 |
YNL088W |
Topoisomerase II |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
VMR1 |
YHL035C |
Vacuolar membrane protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RFC3 |
YNL290W |
Subunit of heteropentameric Replication factor C (RF-C) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YGL039W |
YGL039W |
Aldehyde reductase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NOP14 |
YDL148C |
Nucleolar protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ROD1 |
YOR018W |
Alpha-arrestin involved in ubiquitin-dependent endocytosis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TCP1 |
YDR212W |
Alpha subunit of chaperonin-containing T-complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SSD1 |
YDR293C |
Translational repressor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
LSP1 |
YPL004C |
Eisosome core component |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MRPL7 |
YDR237W |
Mitochondrial ribosomal protein of the large subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RBG2 |
YGR173W |
Protein with a role in translation |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RCL1 |
YOL010W |
Endonuclease that cleaves pre-rRNA at site A2 for 18S rRNA biogenesis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RBG1 |
YAL036C |
Member of the DRG family of GTP-binding proteins |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PBA1 |
YLR199C |
Protein involved in 20S proteasome assembly |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
IPI3 |
YNL182C |
Component of the Rix1 complex and pre-replicative complexes (pre-RCs) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TIF4631 |
YGR162W |
Translation initiation factor eIF4G and scaffold protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RRP12 |
YPL012W |
Protein required for export of the ribosomal subunits |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YAP1801 |
YHR161C |
Protein of the AP180 family, involved in clathrin cage assembly |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HOG1 |
YLR113W |
Mitogen-activated protein kinase involved in osmoregulation |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MRX6 |
YNL295W |
Mitochondrial ribosome-associated protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YCL019W |
YCL019W |
Retrotransposon TYA Gag and TYB Pol genes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YDR261W-B |
YDR261W-B |
Retrotransposon TYA Gag and TYB Pol genes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PRE10 |
YOR362C |
Alpha 7 subunit of the 20S proteasome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SFB2 |
YNL049C |
Component of the Sec23p-Sfb2p heterodimer of the COPII vesicle coat |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SEC28 |
YIL076W |
Epsilon-COP subunit of the coatomer |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PSP2 |
YML017W |
Asn rich cytoplasmic protein that contains RGG motifs |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YDR341C |
YDR341C |
Arginyl-tRNA synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SUI2 |
YJR007W |
Alpha subunit of the translation initiation factor eIF2 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NOG1 |
YPL093W |
Putative GTPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
VMA6 |
YLR447C |
Subunit d of the V0 integral membrane domain of V-ATPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PDR16 |
YNL231C |
Phosphatidylinositol transfer protein (PITP) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PDB1 |
YBR221C |
E1 beta subunit of the pyruvate dehydrogenase (PDH) complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RNA1 |
YMR235C |
GTPase activating protein (GAP) for Gsp1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPA49 |
YNL248C |
RNA polymerase I subunit A49 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SUB2 |
YDL084W |
Component of the TREX complex required for nuclear mRNA export |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ORC5 |
YNL261W |
Subunit of the origin recognition complex (ORC) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NOG2 |
YNR053C |
Putative GTPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SLA2 |
YNL243W |
Adaptor protein that links actin to clathrin and endocytosis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NMD3 |
YHR170W |
Protein involved in nuclear export of the large ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SIF2 |
YBR103W |
WD40 repeat-containing subunit of Set3C histone deacetylase complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
VIP1 |
YLR410W |
Bifunctional inositol pyrophosphate kinase and phosphatase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TCB1 |
YOR086C |
Lipid-binding ER protein involved in ER-plasma membrane tethering |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NEW1 |
YPL226W |
Translation termination and ribosome biogenesis factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
WHI4 |
YDL224C |
Putative RNA binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
WHI3 |
YNL197C |
RNA binding protein that modulates mRNA stability |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RCY1 |
YJL204C |
F-box protein involved in recycling endocytosed proteins |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PSP1 |
YDR505C |
Asn and gln rich protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
UTP10 |
YJL109C |
Nucleolar protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
URB1 |
YKL014C |
Protein required for the normal accumulation of 25S and 5.8S rRNAs |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TGL4 |
YKR089C |
Multifunctional lipase/hydrolase/phospholipase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
STE5 |
YDR103W |
Pheromone-responsive MAPK scaffold protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MSH2 |
YOL090W |
Protein that binds to DNA mismatches |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SLA1 |
YBL007C |
Cytoskeletal protein binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PPZ2 |
YDR436W |
Serine/threonine protein phosphatase Z, isoform of Ppz1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TCB3 |
YML072C |
Cortical ER protein involved in ER-plasma membrane tethering |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
VPS13 |
YLL040C |
Lipid transport protein involved in prospore membrane morphogenesis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
IDH2 |
YOR136W |
Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TRP5 |
YGL026C |
Tryptophan synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YEF3 |
YLR249W |
Translation elongation factor 3 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MRPL17 |
YNL252C |
Mitochondrial ribosomal protein of the large subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PRE9 |
YGR135W |
Alpha 3 subunit of the 20S proteasome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MHF2 |
YDL160C-A |
Component of the heterotetrameric MHF histone-fold complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RFC2 |
YJR068W |
Subunit of heteropentameric Replication factor C (RF-C) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
UPF3 |
YGR072W |
Component of the nonsense-mediated mRNA decay (NMD) pathway |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PCT1 |
YGR202C |
Cholinephosphate cytidylyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TOA2 |
YKL058W |
TFIIA small subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TRP2 |
YER090W |
Anthranilate synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RCM1 |
YNL022C |
rRNA m5C methyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SRP1 |
YNL189W |
Karyopherin alpha homolog |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TMA23 |
YMR269W |
Nucleolar protein implicated in ribosome biogenesis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SUP45 |
YBR143C |
Polypeptide release factor (eRF1) in translation termination |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YJR029W |
YJR029W |
Retrotransposon TYA Gag and TYB Pol genes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YLR227W-B |
YLR227W-B |
Retrotransposon TYA Gag and TYB Pol genes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RET1 |
YOR207C |
Second-largest subunit of RNA polymerase III |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RAD59 |
YDL059C |
Protein involved DNA double-strand break repair |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SPC29 |
YPL124W |
Inner plaque spindle pole body (SPB) component |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YGR130C |
YGR130C |
Component of the eisosome with unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TIF35 |
YDR429C |
eIF3g subunit of the eukaryotic translation initiation factor 3 (eIF3) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PHO81 |
YGR233C |
Cyclin-dependent kinase (CDK) inhibitor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YPR089W |
YPR089W |
Protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NOP7 |
YGR103W |
Component of several different pre-ribosomal particles |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YAP1 |
YML007W |
Basic leucine zipper (bZIP) transcription factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MSS116 |
YDR194C |
Mitochondrial transcription elongation factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TIF34 |
YMR146C |
eIF3i subunit of the eukaryotic translation initiation factor 3 (eIF3) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PDR5 |
YOR153W |
Plasma membrane ATP-binding cassette (ABC) transporter |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PRS1 |
YKL181W |
5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YCL020W |
YCL020W |
Retrotransposon TYA Gag gene co-transcribed with TYB Pol |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RIO1 |
YOR119C |
Serine kinase involved in cell cycle regulation and rDNA integrity |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PRS5 |
YOL061W |
5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SNU114 |
YKL173W |
GTPase component of U5 snRNP involved in mRNA splicing via spliceosome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
KSP1 |
YHR082C |
Serine/threonine protein kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RRB1 |
YMR131C |
Specific assembly chaperone for ribosomal protein Rpl3p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SUM1 |
YDR310C |
Transcriptional repressor that regulates middle-sporulation genes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPA190 |
YOR341W |
RNA polymerase I largest subunit A190 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
VAC8 |
YEL013W |
Vacuole-specific Myo2p receptor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RRP5 |
YMR229C |
RNA binding protein involved in synthesis of 18S and 5.8S rRNAs |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TAH11 |
YJR046W |
DNA replication licensing factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MAG2 |
YLR427W |
Cytoplasmic protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PIN4 |
YBL051C |
Protein involved in G2/M phase progression and response to DNA damage |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MIT1 |
YEL007W |
Transcriptional regulator of pseudohyphal growth |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MIT1 |
YEL007W |
Transcriptional regulator of pseudohyphal growth |
genetic |
1 |
1 |
1 |
Negative Genetic |
IKI3 |
YLR384C |
Subunit of Elongator complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MDL1 |
YLR188W |
Mitochondrial inner membrane half-type ABC transporter |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NOC2 |
YOR206W |
Protein involved in ribosome biogenesis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SWI5 |
YDR146C |
Transcription factor that recruits Mediator and Swi/Snf complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SWI5 |
YDR146C |
Transcription factor that recruits Mediator and Swi/Snf complexes |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
VTC4 |
YJL012C |
Vacuolar membrane polyphosphate polymerase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YKR018C |
YKR018C |
Protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SEC16 |
YPL085W |
COPII vesicle coat protein required for ER transport vesicle budding |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SEC18 |
YBR080C |
AAA ATPase and SNARE disassembly chaperone |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HSL1 |
YKL101W |
Nim1p-related protein kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
VID27 |
YNL212W |
Cytoplasmic protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PET127 |
YOR017W |
Protein with a role in 5'-end processing of mitochondrial RNAs |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RIX7 |
YLL034C |
Putative ATPase of the AAA family |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SPO14 |
YKR031C |
Phospholipase D |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PDR1 |
YGL013C |
Transcription factor that regulates the pleiotropic drug response |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PIM1 |
YBL022C |
ATP-dependent Lon protease |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SMC2 |
YFR031C |
Subunit of the condensin complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
UTP22 |
YGR090W |
Component of the small-subunit processome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SEC3 |
YER008C |
Subunit of the exocyst complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RSE1 |
YML049C |
Protein involved in pre-mRNA splicing |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TAF2 |
YCR042C |
TFIID subunit (150 kDa) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
XRN1 |
YGL173C |
Evolutionarily-conserved 5'-3' exonuclease |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
XRN1 |
YGL173C |
Evolutionarily-conserved 5'-3' exonuclease |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
YOR142W-B |
YOR142W-B |
Retrotransposon TYA Gag and TYB Pol genes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TAO3 |
YIL129C |
Component of the RAM signaling network |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YMR050C |
YMR050C |
Retrotransposon TYA Gag and TYB Pol genes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
VMA8 |
YEL051W |
Subunit D of the V1 peripheral membrane domain of V-ATPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TIF6 |
YPR016C |
Constituent of 66S pre-ribosomal particles |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YBL005W-B |
YBL005W-B |
Retrotransposon TYA Gag and TYB Pol genes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
VPS1 |
YKR001C |
Dynamin-like GTPase required for vacuolar sorting |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HSP42 |
YDR171W |
Small heat shock protein (sHSP) with chaperone activity |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
LEO1 |
YOR123C |
Component of the Paf1 complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MIR1 |
YJR077C |
Mitochondrial phosphate carrier |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
VTC3 |
YPL019C |
Regulatory subunit of the vacuolar transporter chaperone (VTC) complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RGD2 |
YFL047W |
GTPase-activating protein (RhoGAP) for Cdc42p and Rho5p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
JSN1 |
YJR091C |
Member of the Puf family of RNA-binding proteins |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
KRE33 |
YNL132W |
Acetyltransferase required for biogenesis of small ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TPT1 |
YOL102C |
tRNA 2'-phosphotransferase that catalyzes final step in tRNA splicing |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MUK1 |
YPL070W |
Guanine nucleotide exchange factor (GEF) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SKN7 |
YHR206W |
Nuclear response regulator and transcription factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PGC1 |
YPL206C |
Phosphatidylglycerol phospholipase C |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPA43 |
YOR340C |
RNA polymerase I subunit A43 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TWF1 |
YGR080W |
Twinfilin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NGG1 |
YDR176W |
Subunit of chromatin modifying histone acetyltransferase complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HXT7 |
YDR342C |
High-affinity glucose transporter |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SEC10 |
YLR166C |
Essential 100kDa subunit of the exocyst complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HIS3 |
YOR202W |
Imidazoleglycerol-phosphate dehydratase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
UPC2 |
YDR213W |
Sterol regulatory element binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MTC1 |
YJL123C |
Protein of unknown function that may interact with ribosomes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
LSB1 |
YGR136W |
Negative regulator of actin nucleation-promoting factor activity |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PUP2 |
YGR253C |
Alpha 5 subunit of the 20S proteasome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RSP5 |
YER125W |
NEDD4 family E3 ubiquitin ligase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MRH4 |
YGL064C |
Mitochondrial ATP-dependent RNA helicase of the DEAD-box family |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MCM7 |
YBR202W |
Component of the Mcm2-7 hexameric helicase complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NAB6 |
YML117W |
Putative RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NAN1 |
YPL126W |
U3 snoRNP protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NUM1 |
YDR150W |
Protein required for nuclear migration |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MRPL22 |
YNL177C |
Mitochondrial ribosomal protein of the large subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PRS3 |
YHL011C |
5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
REG1 |
YDR028C |
Regulatory subunit of type 1 protein phosphatase Glc7p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
REG1 |
YDR028C |
Regulatory subunit of type 1 protein phosphatase Glc7p |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
LCB5 |
YLR260W |
Minor sphingoid long-chain base kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RRP6 |
YOR001W |
Nuclear exosome exonuclease component |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RRP6 |
YOR001W |
Nuclear exosome exonuclease component |
genetic |
1 |
1 |
1 |
Negative Genetic |
RKM5 |
YLR137W |
Protein lysine methyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TFG1 |
YGR186W |
TFIIF (Transcription Factor II) largest subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
POL3 |
YDL102W |
Catalytic subunit of DNA polymerase delta |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TOM40 |
YMR203W |
Component of the TOM (translocase of outer membrane) complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RRP8 |
YDR083W |
Nucleolar S-adenosylmethionine-dependent rRNA methyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
LYS14 |
YDR034C |
Transcriptional activator involved in regulating lysine biosynthesis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SWI6 |
YLR182W |
Transcription cofactor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SRP40 |
YKR092C |
Nucleolar serine-rich protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PIF1 |
YML061C |
DNA helicase, potent G-quadruplex DNA binder/unwinder |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RXT2 |
YBR095C |
Component of the histone deacetylase Rpd3L complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SGD1 |
YLR336C |
Essential nuclear protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NUP49 |
YGL172W |
FG-nucleoporin component of central core of the nuclear pore complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
VTS1 |
YOR359W |
Flap-structured DNA-binding and RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PIK1 |
YNL267W |
Phosphatidylinositol 4-kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
KIN1 |
YDR122W |
S/T protein kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NUP60 |
YAR002W |
FG-nucleoporin component of central core of the nuclear pore complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YAP1802 |
YGR241C |
Protein of the AP180 family, involved in clathrin cage assembly |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MSB1 |
YOR188W |
Protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PRP39 |
YML046W |
U1 snRNP protein involved in splicing |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ULP1 |
YPL020C |
Protease that specifically cleaves Smt3p protein conjugates |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SNX41 |
YDR425W |
Sorting nexin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TEL2 |
YGR099W |
Subunit of the ASTRA complex, involved in chromatin remodeling |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SKT5 |
YBL061C |
Activator of Chs3p (chitin synthase III) during vegetative growth |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NUP157 |
YER105C |
Subunit of the inner ring of the nuclear pore complex (NPC) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SEC1 |
YDR164C |
Sm-like protein involved in docking and fusion of exocytic vesicles |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SEC1 |
YDR164C |
Sm-like protein involved in docking and fusion of exocytic vesicles |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPA2 |
YLL021W |
Component of the polarisome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YTA6 |
YPL074W |
Putative ATPase of the CDC48/PAS1/SEC18 (AAA) family |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SCD5 |
YOR329C |
Protein required for normal actin organization and endocytosis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
STB4 |
YMR019W |
Putative transcription factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SLH1 |
YGR271W |
Subunit of ribosome-associated quality control trigger complex (RQT) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RAT1 |
YOR048C |
Nuclear 5' to 3' single-stranded RNA exonuclease |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RAT1 |
YOR048C |
Nuclear 5' to 3' single-stranded RNA exonuclease |
genetic |
1 |
1 |
1 |
Negative Genetic |
MCM6 |
YGL201C |
Protein involved in DNA replication |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YCG1 |
YDR325W |
Subunit of the condensin complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SDD3 |
YOL098C |
Putative metalloprotease |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MYO4 |
YAL029C |
Type V myosin motor involved in actin-based transport of cargos |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RIF1 |
YBR275C |
Protein involved in control of DNA replication |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MOT1 |
YPL082C |
Essential protein involved in regulation of transcription |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TOR1 |
YJR066W |
PIK-related protein kinase and rapamycin target |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TOR1 |
YJR066W |
PIK-related protein kinase and rapamycin target |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
MOT2 |
YER068W |
Ubiquitin-protein ligase subunit of the CCR4-NOT complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TAE1 |
YBR261C |
AdoMet-dependent proline methyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NRD1 |
YNL251C |
RNA-binding subunit of Nrd1 complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TAF1 |
YGR274C |
TFIID subunit, involved in RNA pol II transcription initiation |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PDR11 |
YIL013C |
ATP-binding cassette (ABC) transporter |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PAM1 |
YDR251W |
Essential protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MCM3 |
YEL032W |
Protein involved in DNA replication |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RGT1 |
YKL038W |
Glucose-responsive transcription factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SMC3 |
YJL074C |
Subunit of the multiprotein cohesin complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MSH6 |
YDR097C |
Protein required for mismatch repair in mitosis and meiosis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TOM1 |
YDR457W |
E3 ubiquitin ligase of the hect-domain class |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SET5 |
YHR207C |
Methyltransferase involved in methylation of histone H4 Lys5, -8, -12 |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
SLF1 |
YDR515W |
RNA binding protein that associates with polysomes |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
SRO9 |
YCL037C |
Cytoplasmic RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
HST2 |
YPL015C |
Cytoplasmic NAD(+)-dependent protein deacetylase |
physical |
1 |
1 |
1 |
Biochemical Activity |
IKI1 |
YHR187W |
Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
RPB3 |
YIL021W |
RNA polymerase II third largest subunit B44 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPB4 |
YJL140W |
RNA polymerase II subunit B32 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPB5 |
YBR154C |
RNA polymerase subunit ABC27 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPB7 |
YDR404C |
RNA polymerase II subunit B16 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPB8 |
YOR224C |
RNA polymerase subunit ABC14.5 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPB11 |
YOL005C |
RNA polymerase II subunit B12.5 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
IOC2 |
YLR095C |
Subunit of the Isw1b complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ITC1 |
YGL133W |
Subunit of ATP-dependent Isw2p-Itc1p chromatin remodeling complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ITC1 |
YGL133W |
Subunit of ATP-dependent Isw2p-Itc1p chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPT6 |
YGR116W |
Nucleosome remodeling protein |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
HIR3 |
YJR140C |
Subunit of the HIR complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RMP1 |
YLR145W |
Subunit of RNase MRP |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
LSM1 |
YJL124C |
Lsm (Like Sm) protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
PAT1 |
YCR077C |
Deadenylation-dependent mRNA-decapping factor |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
IES1 |
YFL013C |
Subunit of the INO80 chromatin remodeling complex |
physical |
1 |
1 |
1 |
Reconstituted Complex |
IES2 |
YNL215W |
Protein that associates with the INO80 chromatin remodeling complex |
physical |
1 |
1 |
1 |
Reconstituted Complex |
SPT10 |
YJL127C |
Histone H3 acetylase with a role in transcriptional regulation |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SPT21 |
YMR179W |
Protein with a role in transcriptional silencing |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
UBC4 |
YBR082C |
Ubiquitin-conjugating enzyme (E2) |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
UBC5 |
YDR059C |
Ubiquitin-conjugating enzyme |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
SCM3 |
YDL139C |
Nonhistone component of centromeric chromatin |
physical |
1 |
1 |
1 |
Reconstituted Complex |
POL2 |
YNL262W |
Catalytic subunit of DNA polymerase (II) epsilon |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
POL2 |
YNL262W |
Catalytic subunit of DNA polymerase (II) epsilon |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
PKC1 |
YBL105C |
Protein serine/threonine kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
PRB1 |
YEL060C |
Vacuolar proteinase B (yscB) with H3 N-terminal endopeptidase activity |
physical |
1 |
1 |
1 |
Biochemical Activity |
MAD2 |
YJL030W |
Component of the spindle-assembly checkpoint complex |
physical |
1 |
1 |
1 |
Reconstituted Complex |
MEK1 |
YOR351C |
Meiosis-specific serine/threonine protein kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
SAM50 |
YNL026W |
Component of the Sorting and Assembly Machinery (SAM) complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HHT1 |
YBR010W |
Histone H3 |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
PDE2 |
YOR360C |
High-affinity cyclic AMP phosphodiesterase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SPN1 |
YPR133C |
Protein involved in RNA polymerase II transcription |
physical |
1 |
1 |
1 |
Reconstituted Complex |
SGO1 |
YOR073W |
Component of the spindle checkpoint |
genetic |
1 |
1 |
1 |
Dosage Rescue |
REB1 |
YBR049C |
RNA polymerase I enhancer binding protein |
physical |
1 |
1 |
1 |
FRET |
SWR1 |
YDR334W |
Swi2/Snf2-related ATPase |
physical |
1 |
1 |
1 |
Reconstituted Complex |
SCH9 |
YHR205W |
AGC family protein kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
TFC6 |
YDR362C |
Subunit of RNA polymerase III transcription initiation factor complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS0A |
YGR214W |
Ribosomal 40S subunit protein S0A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS1A |
YLR441C |
Ribosomal protein of the small (40S) subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS6A |
YPL090C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS8A |
YBL072C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS9A |
YPL081W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS10A |
YOR293W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS12 |
YOR369C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS18A |
YDR450W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS19A |
YOL121C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS20 |
YHL015W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS22A |
YJL190C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL25 |
YOL127W |
Ribosomal 60S subunit protein L25 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL26A |
YLR344W |
Ribosomal 60S subunit protein L26A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL31A |
YDL075W |
Ribosomal 60S subunit protein L31A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS3 |
YNL178W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS14A |
YCR031C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MES1 |
YGR264C |
Methionyl-tRNA synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
SGV1 |
YPR161C |
Cyclin (Bur2p)-dependent protein kinase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
RAD3 |
YER171W |
5' to 3' DNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SOD1 |
YJR104C |
Cytosolic copper-zinc superoxide dismutase |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
RPN10 |
YHR200W |
Proteasome polyubiquitin receptor |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPN6 |
YDL097C |
Essential, non-ATPase regulatory subunit of the 26S proteasome lid |
genetic |
1 |
1 |
1 |
Negative Genetic |
SGS1 |
YMR190C |
RecQ family nucleolar DNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
YML119W |
YML119W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
MCM22 |
YJR135C |
Outer kinetochore protein and component of the Ctf3 subcomplex |
genetic |
1 |
1 |
1 |
Dosage Lethality |
RAD9 |
YDR217C |
DNA damage-dependent checkpoint protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RAD1 |
YPL022W |
Single-stranded DNA endonuclease (with Rad10p) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RAD5 |
YLR032W |
DNA helicase/Ubiquitin ligase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RPS21B |
YJL136C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
SAS2 |
YMR127C |
Histone acetyltransferase (HAT) catalytic subunit of the SAS complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
SPT4 |
YGR063C |
Spt4p/5p (DSIF) transcription elongation factor complex subunit |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
SPT5 |
YML010W |
Spt4p/5p (DSIF) transcription elongation factor complex subunit |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
KAR2 |
YJL034W |
ATPase involved in protein import into the ER |
genetic |
1 |
1 |
1 |
Positive Genetic |
MRE11 |
YMR224C |
Nuclease subunit of the MRX complex with Rad50p and Xrs2p |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
XRS2 |
YDR369C |
FHA domain-containing component of the Mre11 complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
SLX4 |
YLR135W |
Endonuclease involved in processing DNA |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
MEC1 |
YBR136W |
Genome integrity checkpoint protein and PI kinase superfamily member |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
LEA1 |
YPL213W |
Component of U2 snRNP complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
MSL1 |
YIR009W |
U2B component of U2 snRNP |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
SSN3 |
YPL042C |
Component of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
SIR1 |
YKR101W |
Protein involved in silencing at mating-type loci HML and HMR |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
HOF1 |
YMR032W |
F-BAR protein that regulates actin cytoskeleton organization |
genetic |
1 |
1 |
1 |
Positive Genetic |
PPA2 |
YMR267W |
Mitochondrial inorganic pyrophosphatase |
genetic |
1 |
1 |
1 |
Positive Genetic |
YDJ1 |
YNL064C |
Type I HSP40 co-chaperone |
genetic |
1 |
1 |
1 |
Positive Genetic |
NPL3 |
YDR432W |
RNA-binding protein |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
RRM3 |
YHR031C |
DNA helicase involved in rDNA replication and Ty1 transposition |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
RAD17 |
YOR368W |
Checkpoint protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RAD24 |
YER173W |
Checkpoint protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PRP24 |
YMR268C |
Splicing factor that reanneals snRNPs during spliceosome recycling |
genetic |
1 |
1 |
1 |
Positive Genetic |
TAF3 |
YPL011C |
TFIID subunit (47 kDa) |
genetic |
1 |
1 |
1 |
Positive Genetic |
KAR3 |
YPR141C |
Minus-end-directed microtubule motor |
genetic |
1 |
1 |
1 |
Positive Genetic |
YDR524C-B |
YDR524C-B |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
WTM1 |
YOR230W |
Transcriptional modulator |
genetic |
1 |
1 |
1 |
Positive Genetic |
SRB6 |
YBR253W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
KIN28 |
YDL108W |
Ser/Thr protein kinase and subunit of TFIIK, a TFIIH subassembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
TFB1 |
YDR311W |
Subunit of TFIIH and nucleotide excision repair factor 3 complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
TRS31 |
YDR472W |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
1 |
1 |
1 |
Negative Genetic |
SNM1 |
YDR478W |
Ribonuclease MRP complex subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
LCP5 |
YER127W |
Essential protein involved in maturation of 18S rRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
UTP8 |
YGR128C |
Nucleolar protein required for export of tRNAs from the nucleus |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPP1 |
YHR062C |
Subunit of both RNase MRP and nuclear RNase P |
genetic |
1 |
1 |
1 |
Negative Genetic |
QNS1 |
YHR074W |
Glutamine-dependent NAD(+) synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
UTP25 |
YIL091C |
Nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
SSL1 |
YLR005W |
Subunit of the core form of RNA polymerase transcription factor TFIIH |
genetic |
1 |
1 |
1 |
Negative Genetic |
SDO1 |
YLR022C |
Guanine nucleotide exchange factor (GEF) for Ria1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL15A |
YLR029C |
Ribosomal 60S subunit protein L15A |
genetic |
1 |
1 |
1 |
Negative Genetic |
SMD2 |
YLR275W |
Core Sm protein Sm D2 |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC12 |
YNR026C |
Guanine nucleotide exchange factor (GEF) |
genetic |
1 |
1 |
1 |
Negative Genetic |
WRS1 |
YOL097C |
Cytoplasmic tryptophanyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
LAS17 |
YOR181W |
Actin assembly factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPT4 |
YOR259C |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL5 |
YPL131W |
Ribosomal 60S subunit protein L5 |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRD1 |
YPR112C |
Essential conserved small ribosomal subunit (40s) synthesis factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPN12 |
YFR052W |
Subunit of the 19S regulatory particle of the 26S proteasome lid |
genetic |
1 |
1 |
1 |
Negative Genetic |
YAL064W |
YAL064W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
PAA1 |
YDR071C |
Polyamine acetyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
KAP122 |
YGL016W |
Karyopherin beta |
genetic |
1 |
1 |
1 |
Negative Genetic |
URM1 |
YIL008W |
Ubiquitin-like protein involved in thiolation of cytoplasmic tRNAs |
genetic |
1 |
1 |
1 |
Negative Genetic |
HOM6 |
YJR139C |
Homoserine dehydrogenase (L-homoserine:NADP oxidoreductase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS51 |
YKR020W |
Component of the GARP (Golgi-associated retrograde protein) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SCS7 |
YMR272C |
Sphingolipid alpha-hydroxylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
WHI5 |
YOR083W |
Repressor of G1 transcription |
genetic |
1 |
1 |
1 |
Negative Genetic |
TVP23 |
YDR084C |
Integral membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
SAC6 |
YDR129C |
Fimbrin, actin-bundling protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
MSC2 |
YDR205W |
Endoplasmic reticulum zinc transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
SXM1 |
YDR395W |
Nuclear transport factor (karyopherin) |
genetic |
1 |
1 |
1 |
Negative Genetic |
YFH7 |
YFR007W |
Putative kinase with similarity to the PRK/URK/PANK kinase subfamily |
genetic |
1 |
1 |
1 |
Negative Genetic |
TRX2 |
YGR209C |
Cytoplasmic thioredoxin isoenzyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
OSH3 |
YHR073W |
Member of an oxysterol-binding protein family |
genetic |
1 |
1 |
1 |
Negative Genetic |
MPH1 |
YIR002C |
3'-5' DNA helicase involved in error-free bypass of DNA lesions |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRY3 |
YJL078C |
GPI-anchored cell wall protein involved in export of sterols |
genetic |
1 |
1 |
1 |
Negative Genetic |
MAD1 |
YGL086W |
Coiled-coil protein involved in spindle-assembly checkpoint |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
MAD3 |
YJL013C |
Subunit of spindle-assembly checkpoint complex |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
VBA5 |
YKR105C |
Plasma membrane protein of the Major Facilitator Superfamily (MFS) |
genetic |
1 |
1 |
1 |
Negative Genetic |
YLL053C |
YLL053C |
Putative protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
IRC25 |
YLR021W |
Component of a heterodimeric Poc4p-Irc25p chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
SMA2 |
YML066C |
Meiosis-specific prospore membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
VBA1 |
YMR088C |
Permease of basic amino acids in the vacuolar membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
IMP1 |
YMR150C |
Catalytic subunit of mitochondrial inner membrane peptidase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
YMR242W-A |
YMR242W-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
RSM19 |
YNR037C |
Mitochondrial ribosomal protein of the small subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
LAG2 |
YOL025W |
Protein that negatively regulates the SCF E3-ubiquitin ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
THI20 |
YOL055C |
Trifunctional enzyme of thiamine biosynthesis, degradation and salvage |
genetic |
1 |
1 |
1 |
Negative Genetic |
YOL131W |
YOL131W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEY1 |
YOR165W |
Dynamin-like GTPase that mediates homotypic ER fusion |
genetic |
1 |
1 |
1 |
Negative Genetic |
PMA1 |
YGL008C |
Plasma membrane P2-type H+-ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEN1 |
YLR430W |
ATP-dependent 5' to 3' RNA/DNA and DNA helicase |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
MOG1 |
YJR074W |
Conserved nuclear protein that interacts with GTP-Gsp1p |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RPL20B |
YOR312C |
Ribosomal 60S subunit protein L20B |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
RPB9 |
YGL070C |
RNA polymerase II subunit B12.6 |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
YPC1 |
YBR183W |
Alkaline ceramidase |
genetic |
1 |
1 |
1 |
Positive Genetic |
HHO1 |
YPL127C |
Histone H1, linker histone with roles in meiosis and sporulation |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HHO1 |
YPL127C |
Histone H1, linker histone with roles in meiosis and sporulation |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
BEM4 |
YPL161C |
Protein involved in establishment of cell polarity and bud emergence |
genetic |
1 |
1 |
1 |
Negative Genetic |
CCE1 |
YKL011C |
Mitochondrial cruciform cutting endonuclease |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ELC1 |
YPL046C |
Elongin C, conserved among eukaryotes |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
EAP1 |
YKL204W |
eIF4E-associated protein, competes with eIF4G for binding to eIF4E |
genetic |
1 |
1 |
1 |
Positive Genetic |
DBF2 |
YGR092W |
Ser/Thr kinase involved in transcription and stress response |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
FUS3 |
YBL016W |
Mitogen-activated serine/threonine protein kinase involved in mating |
genetic |
1 |
1 |
1 |
Negative Genetic |
EXO70 |
YJL085W |
Subunit of the exocyst complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DHR2 |
YKL078W |
Predominantly nucleolar DEAH-box ATP-dependent RNA helicase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
APL4 |
YPR029C |
Gamma-adaptin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ATG1 |
YGL180W |
Protein serine/threonine kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ARH1 |
YDR376W |
Oxidoreductase of the mitochondrial inner membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
ATP20 |
YPR020W |
Subunit g of the mitochondrial F1F0 ATP synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
CSM1 |
YCR086W |
Nucleolar protein that mediates homolog segregation during meiosis I |
genetic |
1 |
1 |
1 |
Negative Genetic |
DAL82 |
YNL314W |
Positive regulator of allophanate inducible genes |
genetic |
1 |
1 |
1 |
Negative Genetic |
GNA1 |
YFL017C |
Glucosamine-6-phosphate acetyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC34 |
YDR054C |
Ubiquitin-conjugating enzyme (E2) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
BMT2 |
YBR141C |
Nucleolar S-adenosylmethionine-dependent rRNA methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ASK10 |
YGR097W |
Regulator of the Fps1p glycerol channel |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ELP6 |
YMR312W |
Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
ELP6 |
YMR312W |
Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
COG4 |
YPR105C |
Essential component of the conserved oligomeric Golgi complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
COG6 |
YNL041C |
Component of the conserved oligomeric Golgi complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ELP3 |
YPL086C |
Subunit of Elongator complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ELP4 |
YPL101W |
Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
GRC3 |
YLL035W |
Polynucleotide kinase present on rDNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
BRF1 |
YGR246C |
TFIIIB B-related factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CBF1 |
YJR060W |
Basic helix-loop-helix (bHLH) protein |
physical |
1 |
1 |
1 |
FRET |
BUB1 |
YGR188C |
Protein kinase involved in the cell cycle checkpoint into anaphase |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
DBF4 |
YDR052C |
Regulatory subunit of Cdc7p-Dbf4p kinase complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DBF4 |
YDR052C |
Regulatory subunit of Cdc7p-Dbf4p kinase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
DBP5 |
YOR046C |
Cytoplasmic ATP-dependent RNA helicase of the DEAD-box family |
genetic |
1 |
1 |
1 |
Negative Genetic |
ECO1 |
YFR027W |
Acetyltransferase required for sister chromatid cohesion |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
CBF2 |
YGR140W |
Essential kinetochore protein |
genetic |
1 |
1 |
1 |
Dosage Lethality |
ATG2 |
YNL242W |
Peripheral membrane protein required for autophagic vesicle formation |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CCS1 |
YMR038C |
Copper chaperone for superoxide dismutase Sod1p |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
BNR1 |
YIL159W |
Formin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DAL80 |
YKR034W |
Negative regulator of genes in multiple nitrogen degradation pathways |
genetic |
1 |
1 |
1 |
Negative Genetic |
ESC2 |
YDR363W |
Sumo-like domain protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
DBP1 |
YPL119C |
ATP-dependent RNA helicase of the DEAD-box protein family |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DOT1 |
YDR440W |
Nucleosomal histone H3-Lys79 methylase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CDC19 |
YAL038W |
Pyruvate kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
GIC2 |
YDR309C |
Rho-family GTPase interacting protein and Cdc42p effector |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
AZF1 |
YOR113W |
Zinc-finger transcription factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CLA4 |
YNL298W |
Cdc42p-activated signal transducing kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HAC1 |
YFL031W |
Basic leucine zipper (bZIP) transcription factor (ATF/CREB1 homolog) |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
EUC1 |
YMR111C |
Sequence-specific DNA binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
ECM21 |
YBL101C |
Alpha-arrestin, ubiquitin ligase adaptor for Rsp5p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GTA1 |
YEL043W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
HEM14 |
YER014W |
Protoporphyrinogen oxidase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CUE1 |
YMR264W |
Ubiquitin-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ASE1 |
YOR058C |
Mitotic spindle midzone-localized microtubule bundling protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CUE3 |
YGL110C |
Subunit of ribosome-associated quality control trigger complex (RQT) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CSR1 |
YLR380W |
Phosphatidylinositol transfer protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
CHA1 |
YCL064C |
Catabolic L-serine (L-threonine) deaminase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
AIM26 |
YKL037W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
GIS2 |
YNL255C |
Translational activator for mRNAs with internal ribosome entry sites |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ALT1 |
YLR089C |
Alanine transaminase (glutamic pyruvic transaminase) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ACL4 |
YDR161W |
Specific assembly chaperone for ribosomal protein Rpl4a/Rpl4b |
genetic |
1 |
1 |
1 |
Negative Genetic |
GSH1 |
YJL101C |
Gamma glutamylcysteine synthetase |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
GVP36 |
YIL041W |
BAR domain protein that localizes to early and late Golgi vesicles |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
APJ1 |
YNL077W |
Hsp40 chaperone with a role in SUMO-mediated protein degradation |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GSC2 |
YGR032W |
Catalytic subunit of 1,3-beta-glucan synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DFG16 |
YOR030W |
Probable multiple transmembrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
EFR3 |
YMR212C |
Protein required for Stt4-containing PI kinase complex localization |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
FAA3 |
YIL009W |
Long chain fatty acyl-CoA synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ALK1 |
YGL021W |
Atypical protein kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GRS2 |
YPR081C |
Glycine-tRNA synthetase, not expressed under normal growth conditions |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
AFG1 |
YEL052W |
Protein that may act as a chaperone for cytochrome c oxidase subunits |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CDC1 |
YDR182W |
Putative mannose-ethanolamine phosphate phosphodiesterase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
EXO5 |
YBR163W |
Mitochondrial 5'-3' exonuclease and sliding exonuclease |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CUP1-1 |
YHR053C |
Metallothionein |
genetic |
1 |
1 |
1 |
Dosage Rescue |
DBR1 |
YKL149C |
RNA lariat debranching enzyme |
genetic |
1 |
1 |
1 |
Negative Genetic |