Standard name Systematic name Name description Description
SEC12 YNR026C Guanine nucleotide exchange factor (GEF) Guanine nucleotide exchange factor (GEF); activates Sar1p by catalyzing the exchange of GDP for GTP; required for the initiation of COPII vesicle formation in ER to Golgi transport; glycosylated integral membrane protein of the ER; SEC12 has a paralog, SED4, that arose from the whole genome duplication
Visualize the interactome of SEC12
Links to external databases:
SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)
G1(P) 10

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.147 0.293 0.204
ER 0.824 0.703 0.726
Cort. Patches NaN 0.054 NaN
Cell Periphery NaN NaN 0.070
Mito NaN NaN 0.102

GFP localization & abundance

GFP localization GFP abundance
ER 6160

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
SEC12 0 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
SAR1 YPL218W ARF family GTPase genetic 8 4 7 Dosage Rescue, Dosage Rescue, Dosage Rescue, Dosage Rescue, Dosage Rescue, Phenotypic Enhancement, Phenotypic Suppression, Synthetic Rescue
IRE1 YHR079C Serine-threonine kinase and endoribonuclease genetic 5 3 5 Dosage Rescue, Dosage Rescue, Synthetic Growth Defect, Negative Genetic, Negative Genetic
HAC1 YFL031W Basic leucine zipper (bZIP) transcription factor (ATF/CREB1 homolog) genetic 4 2 3 Dosage Rescue, Negative Genetic, Negative Genetic, Negative Genetic
MUD2 YKL074C Protein involved in early pre-mRNA splicing genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
HRR25 YPL204W Conserved casein kinase, monopolin subunit genetic 3 2 3 Synthetic Rescue, Synthetic Rescue, Phenotypic Suppression
EXG1 YLR300W Major exo-1,3-beta-glucanase of the cell wall genetic 3 2 3 Dosage Rescue, Negative Genetic, Dosage Rescue
SED4 YCR067C Integral ER membrane protein that stimulates Sar1p GTPase activity genetic 3 2 3 Synthetic Growth Defect, Negative Genetic, Negative Genetic
NEM1 YHR004C Probable catalytic subunit of Nem1p-Spo7p phosphatase holoenzyme genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
PIN4 YBL051C Protein involved in G2/M phase progression and response to DNA damage genetic 3 3 2 Positive Genetic, Synthetic Rescue, Phenotypic Suppression
SAR1 YPL218W ARF family GTPase physical 3 3 2 Biochemical Activity, Co-crystal Structure, Reconstituted Complex
IES4 YOR189W Component of the INO80 chromatiin remodeling complex genetic 3 2 2 Positive Genetic, Negative Genetic, Positive Genetic
SRN2 YLR119W Component of the ESCRT-I complex genetic 3 2 2 Positive Genetic, Positive Genetic, Negative Genetic
ARP9 YMR033W Component of both the SWI/SNF and RSC chromatin remodeling complexes genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
NAM8 YHR086W RNA binding protein, component of the U1 snRNP protein genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SDC1 YDR469W Subunit of the COMPASS (Set1C) complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
BUD13 YGL174W Subunit of the RES complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
NUP188 YML103C Subunit of the inner ring of the nuclear pore complex (NPC) genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
BUG1 YDL099W Cis-golgi localized protein involved in ER to Golgi transport genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
VPS71 YML041C Nucleosome-binding component of the SWR1 complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
TGS1 YPL157W Trimethyl guanosine synthase, conserved nucleolar methyl transferase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SEC31 YDL195W Component of the Sec13p-Sec31p complex of the COPII vesicle coat genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SEC16 YPL085W COPII vesicle coat protein required for ER transport vesicle budding genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
CFT2 YLR115W Subunit of the mRNA cleavage and polyadenlylation factor (CPF) genetic 3 2 1 Positive Genetic, Negative Genetic, Negative Genetic
LGE1 YPL055C Protein involved in histone H2B ubiquitination genetic 3 2 1 Positive Genetic, Negative Genetic, Negative Genetic
ERV25 YML012W Member of the p24 family involved in ER to Golgi transport genetic 2 2 2 Positive Genetic, Negative Genetic
MSS4 YDR208W Phosphatidylinositol-4-phosphate 5-kinase genetic 2 2 2 Dosage Rescue, Negative Genetic
SFB3 YHR098C Component of the Sec23p-Sfb3p heterodimer of the COPII vesicle coat genetic 2 2 2 Synthetic Lethality, Negative Genetic
YPT1 YFL038C Rab family GTPase genetic 2 2 2 Synthetic Lethality, Negative Genetic
CBC2 YPL178W Small subunit of the heterodimeric cap binding complex with Sto1p genetic 2 1 2 Negative Genetic, Negative Genetic
CDC23 YHR166C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 2 1 2 Negative Genetic, Negative Genetic
LCB1 YMR296C Component of serine palmitoyltransferase genetic 2 1 2 Negative Genetic, Negative Genetic
KAP114 YGL241W Karyopherin, responsible for nuclear import of specific proteins genetic 2 1 2 Negative Genetic, Negative Genetic
OPI1 YHL020C Transcriptional regulator of a variety of genes genetic 2 1 2 Negative Genetic, Negative Genetic
GRH1 YDR517W Acetylated cis-Golgi protein, homolog of human GRASP65 genetic 2 1 2 Negative Genetic, Negative Genetic
KAP122 YGL016W Karyopherin beta genetic 2 1 2 Negative Genetic, Negative Genetic
BUD27 YFL023W Unconventional prefoldin protein involved in translation initiation genetic 2 1 2 Negative Genetic, Negative Genetic
ISY1 YJR050W Member of the NineTeen Complex (NTC) genetic 2 1 2 Negative Genetic, Negative Genetic
MDY2 YOL111C Protein involved in inserting tail-anchored proteins into ER membranes genetic 2 1 2 Negative Genetic, Negative Genetic
ARP6 YLR085C Actin-related protein that binds nucleosomes genetic 2 1 2 Negative Genetic, Negative Genetic
ESC2 YDR363W Sumo-like domain protein genetic 2 1 2 Negative Genetic, Negative Genetic
ERV29 YGR284C Protein localized to COPII-coated vesicles genetic 2 1 2 Negative Genetic, Negative Genetic
RER1 YCL001W Protein involved in retention of membrane proteins genetic 2 1 2 Negative Genetic, Negative Genetic
BST1 YFL025C GPI inositol deacylase of the endoplasmic reticulum (ER) genetic 2 1 2 Positive Genetic, Positive Genetic
RUD3 YOR216C Golgi matrix protein genetic 2 1 2 Negative Genetic, Negative Genetic
ERG3 YLR056W C-5 sterol desaturase genetic 2 1 2 Positive Genetic, Positive Genetic
MSC1 YML128C Protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
YIP1 YGR172C Integral membrane protein genetic 2 1 2 Synthetic Lethality, Synthetic Lethality
SWC3 YAL011W Protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
SWC5 YBR231C Component of the SWR1 complex genetic 2 1 2 Negative Genetic, Negative Genetic
SWR1 YDR334W Swi2/Snf2-related ATPase genetic 2 1 2 Negative Genetic, Negative Genetic
VPS72 YDR485C Htz1p-binding component of the SWR1 complex genetic 2 1 2 Negative Genetic, Negative Genetic
SPP1 YPL138C Subunit of COMPASS (Set1C) genetic 2 1 2 Negative Genetic, Negative Genetic
SWC4 YGR002C Component of the Swr1p complex that incorporates Htz1p into chromatin genetic 2 1 2 Negative Genetic, Negative Genetic
SPN1 YPR133C Protein involved in RNA polymerase II transcription genetic 2 1 2 Negative Genetic, Negative Genetic
LDB16 YCL005W Protein involved in lipid droplet (LD) assembly genetic 2 1 2 Negative Genetic, Negative Genetic
RSC9 YML127W Component of the RSC chromatin remodeling complex genetic 2 2 1 Positive Genetic, Negative Genetic
NIP1 YMR309C eIF3c subunit of the eukaryotic translation initiation factor 3 (eIF3) genetic 2 2 1 Positive Genetic, Negative Genetic
HIR3 YJR140C Subunit of the HIR complex genetic 2 2 1 Positive Genetic, Negative Genetic
MOB2 YFL034C-B Activator of Cbk1p kinase genetic 2 2 1 Positive Genetic, Negative Genetic
POL3 YDL102W Catalytic subunit of DNA polymerase delta genetic 2 2 1 Positive Genetic, Negative Genetic
YPL225W YPL225W Protein of unknown function genetic 2 2 1 Positive Genetic, Negative Genetic
STI1 YOR027W Evolutionarily-conserved Hsp90 cochaperone genetic 2 2 1 Negative Genetic, Positive Genetic
CLF1 YLR117C Member of the NineTeen Complex (NTC) genetic 2 1 1 Negative Genetic, Negative Genetic
LEO1 YOR123C Component of the Paf1 complex genetic 2 1 1 Negative Genetic, Negative Genetic
POB3 YML069W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) genetic 2 1 1 Negative Genetic, Negative Genetic
RTF1 YGL244W Subunit of RNAPII-associated chromatin remodeling Paf1 complex genetic 2 1 1 Negative Genetic, Negative Genetic
PRP43 YGL120C RNA helicase in the DEAH-box family genetic 2 1 1 Negative Genetic, Negative Genetic
CDC48 YDL126C AAA ATPase with protein-unfoldase activity genetic 2 1 1 Negative Genetic, Negative Genetic
RSC4 YKR008W Component of the RSC chromatin remodeling complex genetic 2 1 1 Negative Genetic, Negative Genetic
AAR2 YBL074C Component of the U5 snRNP complex genetic 2 1 1 Negative Genetic, Negative Genetic
BET3 YKR068C Core component of transport protein particle (TRAPP) complexes I-III genetic 2 1 1 Negative Genetic, Negative Genetic
LUC7 YDL087C Essential protein associated with the U1 snRNP complex genetic 2 1 1 Negative Genetic, Negative Genetic
MED6 YHR058C Subunit of the RNA polymerase II mediator complex genetic 2 1 1 Negative Genetic, Negative Genetic
PCF11 YDR228C mRNA 3' end processing factor genetic 2 1 1 Negative Genetic, Negative Genetic
PRP28 YDR243C Pre-mRNA splicing factor genetic 2 1 1 Negative Genetic, Negative Genetic
PUP3 YER094C Beta 3 subunit of the 20S proteasome genetic 2 1 1 Negative Genetic, Negative Genetic
PRP18 YGR006W Splicing factor and component of snRNP U5 genetic 2 1 1 Negative Genetic, Negative Genetic
RSE1 YML049C Protein involved in pre-mRNA splicing genetic 2 1 1 Negative Genetic, Negative Genetic
PRP11 YDL043C Subunit of the SF3a splicing factor complex genetic 2 1 1 Negative Genetic, Negative Genetic
SCJ1 YMR214W One of several homologs of bacterial chaperone DnaJ genetic 2 1 1 Positive Genetic, Positive Genetic
GSF2 YML048W Endoplasmic reticulum (ER) localized integral membrane protein genetic 2 1 1 Positive Genetic, Positive Genetic
GLE1 YDL207W Cytoplasmic nucleoporin required for polyadenylated mRNA export genetic 2 1 1 Negative Genetic, Negative Genetic
KIN28 YDL108W Ser/Thr protein kinase and subunit of TFIIK, a TFIIH subassembly genetic 2 1 1 Negative Genetic, Negative Genetic
IST3 YIR005W Component of the U2 snRNP genetic 2 1 1 Negative Genetic, Negative Genetic
ESS1 YJR017C Peptidylprolyl-cis/trans-isomerase (PPIase) genetic 2 1 1 Negative Genetic, Negative Genetic
GDS1 YOR355W Protein involved in histone H4 acetylation at ribosomal protein genes genetic 2 1 1 Negative Genetic, Negative Genetic
PRP5 YBR237W RNA helicase in the DEAD-box family genetic 2 1 1 Negative Genetic, Negative Genetic
BOS1 YLR078C v-SNARE (vesicle specific SNAP receptor) genetic 2 1 1 Negative Genetic, Negative Genetic
RPA14 YDR156W RNA polymerase I subunit A14 genetic 2 1 1 Positive Genetic, Positive Genetic
NMD2 YHR077C Protein involved in the nonsense-mediated mRNA decay (NMD) pathway genetic 2 1 1 Synthetic Rescue, Synthetic Rescue
PRP16 YKR086W DEAH-box RNA helicase genetic 2 1 1 Negative Genetic, Negative Genetic
HOC1 YJR075W Alpha-1,6-mannosyltransferase genetic 2 1 1 Negative Genetic, Negative Genetic
MSL5 YLR116W Component of commitment complex genetic 2 1 1 Negative Genetic, Negative Genetic
RDS3 YPR094W Component of the SF3b subcomplex of the U2 snRNP genetic 2 1 1 Negative Genetic, Negative Genetic
EPO1 YMR124W Protein involved in septin-ER tethering genetic 2 1 1 Positive Genetic, Positive Genetic
RPL36A YMR194W Ribosomal 60S subunit protein L36A genetic 2 1 1 Negative Genetic, Negative Genetic
GPI19 YDR437W Subunit of GPI-GlcNAc transferase involved in synthesis of GlcNAc-PI genetic 2 1 1 Negative Genetic, Negative Genetic
SAD1 YFR005C Conserved zinc-finger domain protein involved in pre-mRNA splicing genetic 2 1 1 Negative Genetic, Negative Genetic
DLT1 YMR126C Protein of unknown function genetic 2 1 1 Negative Genetic, Negative Genetic
MET22 YOL064C Bisphosphate-3'-nucleotidase genetic 2 1 1 Negative Genetic, Negative Genetic
SLU7 YDR088C RNA splicing factor genetic 2 1 1 Negative Genetic, Negative Genetic
TAF12 YDR145W Subunit (61/68 kDa) of TFIID and SAGA complexes genetic 2 1 1 Negative Genetic, Negative Genetic
SNU56 YDR240C Component of U1 snRNP required for mRNA splicing via spliceosome genetic 2 1 1 Negative Genetic, Negative Genetic
TRS23 YDR246W Core component of transport protein particle (TRAPP) complexes I-III genetic 2 1 1 Negative Genetic, Negative Genetic
SEC24 YIL109C Component of the Sec23p-Sec24p heterodimer of the COPII vesicle coat genetic 2 1 1 Negative Genetic, Negative Genetic
SNU114 YKL173W GTPase component of U5 snRNP involved in mRNA splicing via spliceosome genetic 2 1 1 Negative Genetic, Negative Genetic
SEC13 YLR208W Structural component of 3 complexes genetic 2 1 1 Negative Genetic, Negative Genetic
YHC1 YLR298C Component of the U1 snRNP complex required for pre-mRNA splicing genetic 2 1 1 Negative Genetic, Negative Genetic
SEC63 YOR254C Essential subunit of Sec63 complex genetic 2 1 1 Negative Genetic, Negative Genetic
SEC62 YPL094C Essential subunit of Sec63 complex genetic 2 1 1 Negative Genetic, Negative Genetic
SEC23 YPR181C GTPase-activating protein, stimulates the GTPase activity of Sar1p genetic 2 1 1 Negative Genetic, Negative Genetic
SEC66 YBR171W Non-essential subunit of Sec63 complex genetic 2 1 1 Negative Genetic, Negative Genetic
SNF4 YGL115W Activating gamma subunit of the AMP-activated Snf1p kinase complex genetic 2 1 1 Negative Genetic, Negative Genetic
SIP2 YGL208W One of three alternate beta subunits of the Snf1 kinase complex genetic 2 1 1 Negative Genetic, Negative Genetic
SKY1 YMR216C SR protein kinase (SRPK) genetic 2 1 1 Negative Genetic, Negative Genetic
SPE2 YOL052C S-adenosylmethionine decarboxylase genetic 2 1 1 Negative Genetic, Negative Genetic
SGT2 YOR007C Glutamine-rich cytoplasmic cochaperone genetic 2 1 1 Negative Genetic, Negative Genetic
SNU66 YOR308C Component of the U4/U6.U5 snRNP complex genetic 2 1 1 Negative Genetic, Negative Genetic
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RAP1 YNL216W Essential DNA-binding transcription regulator that binds many loci regulation 1 1 1 DNA to cDNA expression microarray evidence
MED4 YOR174W Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CHD1 YER164W Chromatin remodeler that regulates various aspects of transcription genetic 1 1 1 Negative Genetic
CEF1 YMR213W Essential splicing factor genetic 1 1 1 Negative Genetic
CWC25 YNL245C Splicing factor required for the first step of pre-mRNA splicing genetic 1 1 1 Negative Genetic
CHL4 YDR254W Outer kinetochore protein required for chromosome stability genetic 1 1 1 Negative Genetic
GWT1 YJL091C Protein involved in the inositol acylation of GlcN-PI genetic 1 1 1 Positive Genetic
PSF1 YDR013W Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p) genetic 1 1 1 Negative Genetic
RPO21 YDL140C RNA polymerase II largest subunit B220 genetic 1 1 1 Negative Genetic
GLC7 YER133W Type 1 S/T protein phosphatase (PP1) catalytic subunit genetic 1 1 1 Negative Genetic
ARP4 YJL081C Nuclear actin-related protein involved in chromatin remodeling genetic 1 1 1 Negative Genetic
IKI3 YLR384C Subunit of Elongator complex genetic 1 1 1 Synthetic Rescue
HSP60 YLR259C Tetradecameric mitochondrial chaperonin genetic 1 1 1 Negative Genetic
POP3 YNL282W Subunit of both RNase MRP and nuclear RNase P genetic 1 1 1 Positive Genetic
PRP45 YAL032C Protein required for pre-mRNA splicing genetic 1 1 1 Negative Genetic
PRP46 YPL151C Member of the NineTeen Complex (NTC) genetic 1 1 1 Negative Genetic
BRE1 YDL074C E3 ubiquitin ligase genetic 1 1 1 Negative Genetic
ARL1 YBR164C Soluble GTPase with a role in regulation of membrane traffic genetic 1 1 1 Negative Genetic
PWP2 YCR057C Conserved 90S pre-ribosomal component genetic 1 1 1 Positive Genetic
MES1 YGR264C Methionyl-tRNA synthetase genetic 1 1 1 Negative Genetic
DBP7 YKR024C Putative ATP-dependent RNA helicase of the DEAD-box family genetic 1 1 1 Negative Genetic
RAT1 YOR048C Nuclear 5' to 3' single-stranded RNA exonuclease genetic 1 1 1 Negative Genetic
SAP155 YFR040W Protein required for function of the Sit4p protein phosphatase genetic 1 1 1 Positive Genetic
LSM1 YJL124C Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
LSM3 YLR438C-A Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
LSM6 YDR378C Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
PRP3 YDR473C Splicing factor genetic 1 1 1 Negative Genetic
DED1 YOR204W ATP-dependent DEAD-box RNA helicase with strand-annealing activity genetic 1 1 1 Positive Genetic
PAB1 YER165W Poly(A) binding protein genetic 1 1 1 Negative Genetic
RPA34 YJL148W RNA polymerase I subunit A34.5 genetic 1 1 1 Positive Genetic
RRP8 YDR083W Nucleolar S-adenosylmethionine-dependent rRNA methyltransferase genetic 1 1 1 Positive Genetic
GCD11 YER025W Gamma subunit of the translation initiation factor eIF2 genetic 1 1 1 Positive Genetic
ARP7 YPR034W Component of both the SWI/SNF and RSC chromatin remodeling complexes genetic 1 1 1 Negative Genetic
RSC58 YLR033W Component of the RSC chromatin remodeling complex genetic 1 1 1 Negative Genetic
RSC8 YFR037C Component of the RSC chromatin remodeling complex genetic 1 1 1 Negative Genetic
MUD1 YBR119W U1 snRNP A protein genetic 1 1 1 Negative Genetic
PRP40 YKL012W U1 snRNP protein involved in splicing genetic 1 1 1 Negative Genetic
REI1 YBR267W Cytoplasmic pre-60S factor genetic 1 1 1 Negative Genetic
RPN1 YHR027C Non-ATPase base subunit of the 19S RP of the 26S proteasome genetic 1 1 1 Negative Genetic
RPN10 YHR200W Proteasome polyubiquitin receptor genetic 1 1 1 Negative Genetic
RPN5 YDL147W Subunit of the CSN and 26S proteasome lid complexes genetic 1 1 1 Negative Genetic
RPN6 YDL097C Essential, non-ATPase regulatory subunit of the 26S proteasome lid genetic 1 1 1 Negative Genetic
RPN12 YFR052W Subunit of the 19S regulatory particle of the 26S proteasome lid genetic 1 1 1 Negative Genetic
RPN8 YOR261C Essential non-ATPase regulatory subunit of the 26S proteasome genetic 1 1 1 Negative Genetic
RPT2 YDL007W ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Negative Genetic
RPT6 YGL048C ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Negative Genetic
HCR1 YLR192C eIF3j component of translation initiation factor 3 (eIF3) genetic 1 1 1 Positive Genetic
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 1 1 1 Negative Genetic
RLI1 YDR091C Essential Fe-S protein genetic 1 1 1 Negative Genetic
MPE1 YKL059C Subunit of CPF cleavage and polyadenylation factor and E3 Ub-ligase genetic 1 1 1 Negative Genetic
PRE1 YER012W Beta 4 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
PRE10 YOR362C Alpha 7 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
CDC39 YCR093W Subunit of the CCR4-NOT1 core complex genetic 1 1 1 Negative Genetic
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein genetic 1 1 1 Negative Genetic
NAM7 YMR080C ATP-dependent RNA helicase of the SFI superfamily physical 1 1 1 Affinity Capture-RNA
NAM7 YMR080C ATP-dependent RNA helicase of the SFI superfamily genetic 1 1 1 Positive Genetic
NUP82 YJL061W Linker nucleoporin component of the nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
REB1 YBR049C RNA polymerase I enhancer binding protein genetic 1 1 1 Negative Genetic
OLA1 YBR025C P-loop ATPase with similarity to human OLA1 and bacterial YchF genetic 1 1 1 Positive Genetic
ASC1 YMR116C G-protein beta subunit and guanine dissociation inhibitor for Gpa2p genetic 1 1 1 Negative Genetic
BUD20 YLR074C C2H2-type zinc finger protein required for ribosome assembly genetic 1 1 1 Positive Genetic
CDC24 YAL041W Guanine nucleotide exchange factor (GEF) for Cdc42p genetic 1 1 1 Positive Genetic
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit genetic 1 1 1 Negative Genetic
CDC36 YDL165W Component of the CCR4-NOT core complex, involved in mRNA decapping genetic 1 1 1 Negative Genetic
CDC45 YLR103C DNA replication initiation factor genetic 1 1 1 Negative Genetic
BUD31 YCR063W Component of the SF3b subcomplex of the U2 snRNP genetic 1 1 1 Negative Genetic
AVO1 YOL078W Component of the membrane-bound TORC2 complex genetic 1 1 1 Negative Genetic
CLP1 YOR250C Component of the cleavage and polyadenylation factor I (CF I) genetic 1 1 1 Negative Genetic
COP1 YDL145C Alpha subunit of COPI vesicle coatomer complex genetic 1 1 1 Negative Genetic
CUS1 YMR240C Protein required for assembly of U2 snRNP into the spliceosome genetic 1 1 1 Negative Genetic
ELP2 YGR200C Subunit of Elongator complex genetic 1 1 1 Synthetic Rescue
ERO1 YML130C Thiol oxidase required for oxidative protein folding in the ER genetic 1 1 1 Positive Genetic
EXO84 YBR102C Exocyst subunit with dual roles in exocytosis and spliceosome assembly genetic 1 1 1 Negative Genetic
FIP1 YJR093C Subunit of cleavage polyadenylation factor (CPF) genetic 1 1 1 Negative Genetic
FKS1 YLR342W Catalytic subunit of 1,3-beta-D-glucan synthase genetic 1 1 1 Positive Genetic
GDI1 YER136W GDP dissociation inhibitor genetic 1 1 1 Negative Genetic
GTR2 YGR163W Subunit of a TORC1-stimulating GTPase and the EGO/GSE complex genetic 1 1 1 Positive Genetic
BDF2 YDL070W Protein involved in transcription initiation genetic 1 1 1 Negative Genetic
IST1 YNL265C Protein with positive role in the multivesicular body sorting pathway genetic 1 1 1 Negative Genetic
COG8 YML071C Component of the conserved oligomeric Golgi complex genetic 1 1 1 Negative Genetic
ISW2 YOR304W ATP-dependent DNA translocase involved in chromatin remodeling genetic 1 1 1 Positive Genetic
HSL1 YKL101W Nim1p-related protein kinase genetic 1 1 1 Negative Genetic
KRR1 YCL059C Nucleolar protein required for rRNA synthesis and ribosomal assembly genetic 1 1 1 Positive Genetic
LCB2 YDR062W Component of serine palmitoyltransferase genetic 1 1 1 Negative Genetic
LSM2 YBL026W Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
GLT1 YDL171C NAD(+)-dependent glutamate synthase (GOGAT) genetic 1 1 1 Negative Genetic
MED1 YPR070W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Positive Genetic
MED11 YMR112C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
COG3 YER157W Essential component of the conserved oligomeric Golgi complex genetic 1 1 1 Negative Genetic
MHR1 YDR296W Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Dosage Rescue
MRM1 YOR201C Ribose methyltransferase genetic 1 1 1 Positive Genetic
MRPL1 YDR116C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Positive Genetic
MRPL13 YKR006C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Positive Genetic
CMD1 YBR109C Calmodulin genetic 1 1 1 Negative Genetic
INO80 YGL150C Nucleosome spacing factor genetic 1 1 1 Positive Genetic
ITC1 YGL133W Subunit of ATP-dependent Isw2p-Itc1p chromatin remodeling complex genetic 1 1 1 Positive Genetic
NHP10 YDL002C Non-essential INO80 chromatin remodeling complex subunit genetic 1 1 1 Positive Genetic
IES5 YER092W Non-essential INO80 chromatin remodeling complex subunit genetic 1 1 1 Positive Genetic
IES1 YFL013C Subunit of the INO80 chromatin remodeling complex genetic 1 1 1 Positive Genetic
NHP6B YBR089C-A High-mobility group (HMG) protein genetic 1 1 1 Negative Genetic
FAS2 YPL231W Alpha subunit of fatty acid synthetase genetic 1 1 1 Positive Genetic
NUP60 YAR002W FG-nucleoporin component of central core of the nuclear pore complex genetic 1 1 1 Negative Genetic
GIM5 YML094W Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Negative Genetic
PAN2 YGL094C Catalytic subunit of the Pan2p-Pan3p poly(A)-ribonuclease complex genetic 1 1 1 Negative Genetic
DIG1 YPL049C MAP kinase-responsive inhibitor of the Ste12p transcription factor genetic 1 1 1 Synthetic Rescue
POL12 YBL035C B subunit of DNA polymerase alpha-primase complex genetic 1 1 1 Positive Genetic
POP7 YBR167C Subunit of RNase MRP, nuclear RNase P and telomerase genetic 1 1 1 Positive Genetic
PRE4 YFR050C Beta 7 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
GLE2 YER107C RNA export factor associated with the nuclear pore complex (NPC) genetic 1 1 1 Synthetic Growth Defect
PRP31 YGR091W Splicing factor genetic 1 1 1 Negative Genetic
PRP4 YPR178W Splicing factor genetic 1 1 1 Negative Genetic
LEA1 YPL213W Component of U2 snRNP complex genetic 1 1 1 Negative Genetic
PRP21 YJL203W Subunit of the SF3a splicing factor complex genetic 1 1 1 Negative Genetic
PAA1 YDR071C Polyamine acetyltransferase genetic 1 1 1 Negative Genetic
PTC4 YBR125C Cytoplasmic type 2C protein phosphatase (PP2C) genetic 1 1 1 Negative Genetic
NOP14 YDL148C Nucleolar protein genetic 1 1 1 Positive Genetic
PRE9 YGR135W Alpha 3 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
PEP4 YPL154C Vacuolar aspartyl protease (proteinase A) genetic 1 1 1 Negative Genetic
RAD16 YBR114W Nucleotide excision repair (NER) protein genetic 1 1 1 Negative Genetic
GCN20 YFR009W Positive regulator of the Gcn2p kinase activity genetic 1 1 1 Positive Genetic
PTI1 YGR156W Essential component of CPF (cleavage and polyadenylation factor) genetic 1 1 1 Negative Genetic
RFC4 YOL094C Subunit of heteropentameric Replication factor C (RF-C) genetic 1 1 1 Negative Genetic
RNA14 YMR061W Component of the cleavage and polyadenylation factor I (CF I) genetic 1 1 1 Negative Genetic
MED8 YBR193C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
RPB10 YOR210W RNA polymerase subunit ABC10-beta genetic 1 1 1 Negative Genetic
DEP1 YAL013W Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
RCO1 YMR075W Essential component of the Rpd3S histone deacetylase complex genetic 1 1 1 Negative Genetic
RPL2A YFR031C-A Ribosomal 60S subunit protein L2A genetic 1 1 1 Negative Genetic
MLH2 YLR035C Protein involved in mismatch repair and meiotic recombination genetic 1 1 1 Negative Genetic
PIL1 YGR086C Eisosome core component genetic 1 1 1 Negative Genetic
MNN10 YDR245W Subunit of a Golgi mannosyltransferase complex genetic 1 1 1 Negative Genetic
HOS4 YIL112W Subunit of the Set3 complex genetic 1 1 1 Negative Genetic
SAP30 YMR263W Component of Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
SDS3 YIL084C Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
RXT2 YBR095C Component of the histone deacetylase Rpd3L complex genetic 1 1 1 Negative Genetic
RXT3 YDL076C Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
CCT8 YJL008C Subunit of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Negative Genetic
PRP9 YDL030W Subunit of the SF3a splicing factor complex genetic 1 1 1 Negative Genetic
BRR1 YPR057W snRNP protein component of spliceosomal snRNPs genetic 1 1 1 Negative Genetic
PRP42 YDR235W U1 snRNP protein involved in splicing genetic 1 1 1 Negative Genetic
CCT6 YDR188W Subunit of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Negative Genetic
SBP1 YHL034C Protein that binds eIF4G and has a role in repression of translation genetic 1 1 1 Negative Genetic
BET5 YML077W Core component of transport protein particle (TRAPP) complexes I-III genetic 1 1 1 Negative Genetic
ACE2 YLR131C Transcription factor required for septum destruction after cytokinesis genetic 1 1 1 Negative Genetic
RPT4 YOR259C ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Negative Genetic
RAV1 YJR033C Subunit of RAVE complex (Rav1p, Rav2p, Skp1p) genetic 1 1 1 Negative Genetic
FUN30 YAL019W Snf2p family member with ATP-dependent chromatin remodeling activity genetic 1 1 1 Positive Genetic
FUN19 YAL034C Non-essential protein of unknown function genetic 1 1 1 Negative Genetic
BRE2 YLR015W Subunit of COMPASS (Set1C) complex genetic 1 1 1 Negative Genetic
GET3 YDL100C Guanine nucleotide exchange factor for Gpa1p genetic 1 1 1 Negative Genetic
GAS1 YMR307W Beta-1,3-glucanosyltransferase required for cell wall assembly genetic 1 1 1 Negative Genetic
FET4 YMR319C Low-affinity Fe(II) transporter of the plasma membrane genetic 1 1 1 Negative Genetic
HYP2 YEL034W Translation elongation factor eIF-5A genetic 1 1 1 Positive Genetic
PPQ1 YPL179W Protein phosphatase that regulates the mating response genetic 1 1 1 Negative Genetic
MGE1 YOR232W Mitochondrial matrix cochaperone genetic 1 1 1 Negative Genetic
PBS2 YJL128C MAP kinase kinase of the HOG signaling pathway genetic 1 1 1 Positive Genetic
HSH49 YOR319W U2-snRNP associated splicing factor genetic 1 1 1 Negative Genetic
FYV10 YIL097W Subunit of GID complex genetic 1 1 1 Negative Genetic
PPZ2 YDR436W Serine/threonine protein phosphatase Z, isoform of Ppz1p genetic 1 1 1 Negative Genetic
PMA2 YPL036W Plasma membrane H+-ATPase genetic 1 1 1 Negative Genetic
DIG2 YDR480W MAP kinase-responsive inhibitor of the Ste12p transcription factor genetic 1 1 1 Synthetic Rescue
GET1 YGL020C Subunit of the GET complex genetic 1 1 1 Negative Genetic
GET2 YER083C Subunit of the GET complex genetic 1 1 1 Negative Genetic
EGD1 YPL037C Subunit beta1 of the nascent polypeptide-associated complex (NAC) genetic 1 1 1 Negative Genetic
PDI1 YCL043C Protein disulfide isomerase genetic 1 1 1 Positive Genetic
LIA1 YJR070C Deoxyhypusine hydroxylase genetic 1 1 1 Positive Genetic
MAE1 YKL029C Mitochondrial malic enzyme genetic 1 1 1 Negative Genetic
MTC5 YDR128W Subunit of SEACAT, a subcomplex of the SEA complex genetic 1 1 1 Positive Genetic
MET30 YIL046W F-box protein containing five copies of the WD40 motif genetic 1 1 1 Positive Genetic
CDC20 YGL116W Activator of anaphase-promoting complex/cyclosome (APC/C) genetic 1 1 1 Negative Genetic
MSI1 YBR195C Subunit of chromatin assembly factor I (CAF-1) genetic 1 1 1 Positive Genetic
ADH4 YGL256W Alcohol dehydrogenase isoenzyme type IV genetic 1 1 1 Negative Genetic
IPA1 YJR141W Protein implicated in pre-mRNA processing and proteasomal degradation genetic 1 1 1 Negative Genetic
RNA1 YMR235C GTPase activating protein (GAP) for Gsp1p genetic 1 1 1 Negative Genetic
GPN3 YLR243W Putative GTPase with a role in biogenesis of RNA pol II and polIII genetic 1 1 1 Positive Genetic
MAK11 YKL021C Protein involved in an early step of 60S ribosomal subunit biogenesis genetic 1 1 1 Negative Genetic
HUL5 YGL141W Multiubiquitin chain assembly factor (E4) genetic 1 1 1 Negative Genetic
DSS4 YPR017C Guanine nucleotide dissociation stimulator for Sec4p genetic 1 1 1 Negative Genetic
CDC4 YFL009W F-box protein required for both the G1/S and G2/M phase transitions genetic 1 1 1 Positive Genetic
PRM2 YIL037C Pheromone-regulated protein genetic 1 1 1 Positive Genetic
BEM3 YPL115C Rho GTPase activating protein (RhoGAP) genetic 1 1 1 Positive Genetic
HIR1 YBL008W Subunit of the HIR complex genetic 1 1 1 Negative Genetic
CIN8 YEL061C Bipolar kinesin motor protein genetic 1 1 1 Negative Genetic
AIM46 YHR199C Protein of unknown function genetic 1 1 1 Negative Genetic
ARE1 YCR048W Acyl-CoA:sterol acyltransferase genetic 1 1 1 Negative Genetic
KRI1 YNL308C Essential nucleolar protein required for 40S ribosome biogenesis genetic 1 1 1 Positive Genetic
HHT1 YBR010W Histone H3 genetic 1 1 1 Negative Genetic
DIA2 YOR080W Origin-binding F-box protein genetic 1 1 1 Negative Genetic
CAF4 YKR036C WD40 repeat-containing protein associated with the CCR4-NOT complex genetic 1 1 1 Negative Genetic
BEM4 YPL161C Protein involved in establishment of cell polarity and bud emergence genetic 1 1 1 Negative Genetic
DAK2 YFL053W Dihydroxyacetone kinase genetic 1 1 1 Negative Genetic
CLB2 YPR119W B-type cyclin involved in cell cycle progression genetic 1 1 1 Negative Genetic
MDH2 YOL126C Cytoplasmic malate dehydrogenase genetic 1 1 1 Negative Genetic
RTT103 YDR289C Protein involved in transcription termination by RNA polymerase II genetic 1 1 1 Negative Genetic
HXT5 YHR096C Hexose transporter with moderate affinity for glucose genetic 1 1 1 Negative Genetic
NDE1 YMR145C Mitochondrial external NADH dehydrogenase genetic 1 1 1 Negative Genetic
LSM8 YJR022W Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
PTC2 YER089C Type 2C protein phosphatase (PP2C) genetic 1 1 1 Negative Genetic
RAD53 YPL153C DNA damage response kinase genetic 1 1 1 Negative Genetic
LIF1 YGL090W Component of the DNA ligase IV complex genetic 1 1 1 Negative Genetic
FUB1 YCR076C Proteasome-binding protein genetic 1 1 1 Negative Genetic
MEH1 YKR007W Subunit of the EGO/GSE complex genetic 1 1 1 Positive Genetic
PTC6 YCR079W Mitochondrial type 2C protein phosphatase (PP2C) genetic 1 1 1 Positive Genetic
DEF1 YKL054C RNAPII degradation factor genetic 1 1 1 Negative Genetic
DBF2 YGR092W Ser/Thr kinase involved in transcription and stress response genetic 1 1 1 Negative Genetic
PPZ1 YML016C Serine/threonine protein phosphatase Z, isoform of Ppz2p genetic 1 1 1 Positive Genetic
RIM11 YMR139W Protein kinase genetic 1 1 1 Negative Genetic
PEX15 YOL044W Tail-anchored type II integral peroxisomal membrane protein genetic 1 1 1 Positive Genetic
MGT1 YDL200C DNA repair methyltransferase (6-O-methylguanine-DNA methylase) genetic 1 1 1 Negative Genetic
POL4 YCR014C DNA polymerase IV genetic 1 1 1 Negative Genetic
CDC7 YDL017W S/T kinase and catalytic subunit of DDK (Dbf4-dependent kinase) genetic 1 1 1 Negative Genetic
RNH203 YLR154C Ribonuclease H2 subunit genetic 1 1 1 Negative Genetic
FMP48 YGR052W Putative protein of unknown function genetic 1 1 1 Negative Genetic
DAD2 YKR083C Essential subunit of the Dam1 complex (aka DASH complex) genetic 1 1 1 Negative Genetic
ECM11 YDR446W Meiosis-specific protein genetic 1 1 1 Negative Genetic
CDD1 YLR245C Cytidine deaminase genetic 1 1 1 Negative Genetic
CSM1 YCR086W Nucleolar protein that mediates homolog segregation during meiosis I genetic 1 1 1 Positive Genetic
ENT3 YJR125C Protein containing an N-terminal epsin-like domain genetic 1 1 1 Positive Genetic
FAR3 YMR052W Protein of unknown function genetic 1 1 1 Negative Genetic
GNA1 YFL017C Glucosamine-6-phosphate acetyltransferase genetic 1 1 1 Positive Genetic
GTR1 YML121W Subunit of a TORC1-stimulating GTPase and the EGO/GSE complex genetic 1 1 1 Positive Genetic
CWC24 YLR323C General splicing factor genetic 1 1 1 Negative Genetic
NDC80 YIL144W Component of the kinetochore-associated Ndc80 complex genetic 1 1 1 Negative Genetic
PKC1 YBL105C Protein serine/threonine kinase genetic 1 1 1 Negative Genetic
RAD4 YER162C Damaged-DNA binding subunit of Nuclear Excision Repair Factor 2 genetic 1 1 1 Negative Genetic
RMD1 YDL001W Cytoplasmic protein required for sporulation genetic 1 1 1 Negative Genetic
ACF4 YJR083C Protein of unknown function genetic 1 1 1 Negative Genetic
JSN1 YJR091C Member of the Puf family of RNA-binding proteins genetic 1 1 1 Negative Genetic
MVP1 YMR004W Protein required for sorting proteins to the vacuole genetic 1 1 1 Negative Genetic
ESL1 YIL151C hEST1A/B (SMG5/6)-like protein genetic 1 1 1 Negative Genetic
GPN2 YOR262W Putative GTPase with a specific role in RNA pol II and polIII biogenes genetic 1 1 1 Negative Genetic
ASK10 YGR097W Regulator of the Fps1p glycerol channel genetic 1 1 1 Negative Genetic
ASK1 YKL052C Essential subunit of the Dam1 complex (aka DASH complex) genetic 1 1 1 Negative Genetic
ELP6 YMR312W Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex genetic 1 1 1 Negative Genetic
NPR2 YEL062W Subunit of the Iml1p/SEACIT complex genetic 1 1 1 Negative Genetic
GMH1 YKR030W Golgi membrane protein of unknown function genetic 1 1 1 Negative Genetic
COG1 YGL223C Essential component of the conserved oligomeric Golgi complex genetic 1 1 1 Synthetic Growth Defect
ELP3 YPL086C Subunit of Elongator complex genetic 1 1 1 Synthetic Rescue
ELP4 YPL101W Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex genetic 1 1 1 Synthetic Rescue
IKI1 YHR187W Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex genetic 1 1 1 Synthetic Rescue
RNA15 YGL044C Component of the cleavage and polyadenylation factor I (CF I) genetic 1 1 1 Negative Genetic
PEX12 YMR026C C3HC4-type RING-finger peroxin and E3 ubiquitin ligase genetic 1 1 1 Positive Genetic
CDC21 YOR074C Thymidylate synthase genetic 1 1 1 Negative Genetic
HOT1 YMR172W Transcription factor for glycerol biosynthetic genes genetic 1 1 1 Negative Genetic
CET1 YPL228W RNA 5'-triphosphatase involved in mRNA 5' capping genetic 1 1 1 Negative Genetic
IES3 YLR052W Subunit of the INO80 chromatin remodeling complex genetic 1 1 1 Positive Genetic
CBF1 YJR060W Basic helix-loop-helix (bHLH) protein genetic 1 1 1 Negative Genetic
SCL1 YGL011C Alpha 1 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
MIF2 YKL089W Centromeric CDEIII region binding protein genetic 1 1 1 Negative Genetic
RAD9 YDR217C DNA damage-dependent checkpoint protein genetic 1 1 1 Negative Genetic
BUR6 YER159C Subunit of a heterodimeric NC2 transcription regulator complex genetic 1 1 1 Negative Genetic
DBF4 YDR052C Regulatory subunit of Cdc7p-Dbf4p kinase complex genetic 1 1 1 Negative Genetic
DBP5 YOR046C Cytoplasmic ATP-dependent RNA helicase of the DEAD-box family genetic 1 1 1 Negative Genetic
GIM4 YEL003W Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Negative Genetic
IOC4 YMR044W Member of a complex (Isw1b) with Isw1p and Ioc2p genetic 1 1 1 Negative Genetic
ATS1 YAL020C Protein required for modification of wobble nucleosides in tRNA genetic 1 1 1 Synthetic Rescue
OST3 YOR085W Gamma subunit of the oligosaccharyltransferase complex of the ER lumen genetic 1 1 1 Positive Genetic
PUP1 YOR157C Beta 2 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
RFM1 YOR279C Component of the Sum1p-Rfm1p-Hst1p complex genetic 1 1 1 Positive Genetic
BET1 YIL004C Type II membrane protein required for vesicular transport genetic 1 1 1 Negative Genetic
RAP1 YNL216W Essential DNA-binding transcription regulator that binds many loci genetic 1 1 1 Positive Genetic
RRD1 YIL153W Peptidyl-prolyl cis/trans-isomerase genetic 1 1 1 Positive Genetic
RCY1 YJL204C F-box protein involved in recycling endocytosed proteins genetic 1 1 1 Positive Genetic
PEP8 YJL053W Vacuolar protein component of the retromer genetic 1 1 1 Positive Genetic
MKC7 YDR144C GPI-anchored aspartyl protease genetic 1 1 1 Positive Genetic
KTI11 YBL071W-A Zn-ribbon protein that co-purifies with Dph1 and Dph2 genetic 1 1 1 Synthetic Rescue
MST28 YAR033W Putative integral membrane protein, involved in vesicle formation genetic 1 1 1 Negative Genetic
ABF1 YKL112W DNA binding protein with possible chromatin-reorganizing activity genetic 1 1 1 Negative Genetic
FCP1 YMR277W Carboxy-terminal domain (CTD) phosphatase genetic 1 1 1 Negative Genetic
EMC5 YIL027C Member of conserved ER transmembrane complex genetic 1 1 1 Positive Genetic
INP53 YOR109W Polyphosphatidylinositol phosphatase genetic 1 1 1 Negative Genetic
HFA1 YMR207C Mitochondrial acetyl-coenzyme A carboxylase genetic 1 1 1 Positive Genetic
HMT1 YBR034C Nuclear SAM-dependent mono- and asymmetric methyltransferase genetic 1 1 1 Negative Genetic
ECM27 YJR106W Protein involved in calcium homeostasis and exit from quiescence genetic 1 1 1 Negative Genetic
NNF2 YGR089W Protein that exhibits physical and genetic interactions with Rpb8p genetic 1 1 1 Negative Genetic
PRP22 YER013W DEAH-box RNA-dependent ATPase/ATP-dependent RNA helicase genetic 1 1 1 Negative Genetic
BAT2 YJR148W Cytosolic branched-chain amino acid (BCAA) aminotransferase genetic 1 1 1 Negative Genetic
PEX30 YLR324W ER-resident protein involved in peroxisomal biogenesis genetic 1 1 1 Negative Genetic
CLA4 YNL298W Cdc42p-activated signal transducing kinase genetic 1 1 1 Positive Genetic
MCA1 YOR197W Ca2+-dependent cysteine protease genetic 1 1 1 Negative Genetic
HRD1 YOL013C Ubiquitin-protein ligase involved in ER-associated degradation (ERAD) genetic 1 1 1 Phenotypic Enhancement
BSD2 YBR290W Heavy metal ion homeostasis protein genetic 1 1 1 Positive Genetic
REC8 YPR007C Meiosis-specific component of the sister chromatid cohesion complex genetic 1 1 1 Negative Genetic
RER1 YCL001W Protein involved in retention of membrane proteins physical 1 1 1 PCA
PLB3 YOL011W Phospholipase B (lysophospholipase) involved in lipid metabolism genetic 1 1 1 Dosage Rescue
RPS2 YGL123W Protein component of the small (40S) subunit genetic 1 1 1 Positive Genetic
ATG10 YLL042C Conserved E2-like conjugating enzyme genetic 1 1 1 Negative Genetic
BET4 YJL031C Alpha subunit of Type II geranylgeranyltransferase genetic 1 1 1 Negative Genetic
RPL11B YGR085C Ribosomal 60S subunit protein L11B genetic 1 1 1 Negative Genetic
ARL3 YPL051W ARF-like small GTPase of the RAS superfamily genetic 1 1 1 Negative Genetic
DYS1 YHR068W Deoxyhypusine synthase genetic 1 1 1 Negative Genetic
ERV14 YGL054C COPII-coated vesicle protein genetic 1 1 1 Negative Genetic
MON2 YNL297C Protein with a role in endocytosis and vacuole integrity genetic 1 1 1 Positive Genetic
RPN4 YDL020C Transcription factor that stimulates expression of proteasome genes genetic 1 1 1 Negative Genetic
PER33 YLR064W Protein that localizes to the endoplasmic reticulum genetic 1 1 1 Negative Genetic
MOG1 YJR074W Conserved nuclear protein that interacts with GTP-Gsp1p genetic 1 1 1 Negative Genetic
RPL29 YFR032C-A Ribosomal 60S subunit protein L29 genetic 1 1 1 Negative Genetic
DPM1 YPR183W Dolichol phosphate mannose (Dol-P-Man) synthase of ER membrane genetic 1 1 1 Positive Genetic
ERG5 YMR015C C-22 sterol desaturase genetic 1 1 1 Negative Genetic
MIT1 YEL007W Transcriptional regulator of pseudohyphal growth genetic 1 1 1 Positive Genetic
AIM44 YPL158C Regulator of Cdc42p and Rho1p genetic 1 1 1 Positive Genetic
PRP24 YMR268C Splicing factor that reanneals snRNPs during spliceosome recycling genetic 1 1 1 Negative Genetic
SAC7 YDR389W GTPase activating protein (GAP) for Rho1p genetic 1 1 1 Negative Genetic
EMC6 YLL014W Member of conserved ER transmembrane complex genetic 1 1 1 Negative Genetic
MRC1 YCL061C S-phase checkpoint protein required for DNA replication genetic 1 1 1 Negative Genetic
INH1 YDL181W Protein that inhibits ATP hydrolysis by the F1F0-ATP synthase genetic 1 1 1 Positive Genetic
CAT2 YML042W Carnitine acetyl-CoA transferase genetic 1 1 1 Negative Genetic
BTS1 YPL069C Geranylgeranyl diphosphate synthase (GGPPS) genetic 1 1 1 Negative Genetic
CSF1 YLR087C Protein with structural similarity to lipid transport protein Vps13p genetic 1 1 1 Negative Genetic
MMS1 YPR164W Subunit of E3 ubiquitin ligase complex involved in replication repair genetic 1 1 1 Negative Genetic
GAT2 YMR136W Protein containing GATA family zinc finger motifs genetic 1 1 1 Negative Genetic
RMI1 YPL024W Subunit of the RecQ (Sgs1p) - Topo III (Top3p) complex genetic 1 1 1 Negative Genetic
ERG2 YMR202W C-8 sterol isomerase genetic 1 1 1 Positive Genetic
MIG2 YGL209W Zinc finger transcriptional repressor genetic 1 1 1 Negative Genetic
DDR2 YOL052C-A Multi-stress response protein genetic 1 1 1 Negative Genetic
BSC6 YOL137W Protein of unknown function with 8 putative transmembrane segments genetic 1 1 1 Negative Genetic
RIO1 YOR119C Serine kinase involved in cell cycle regulation and rDNA integrity genetic 1 1 1 Positive Genetic
RPL40B YKR094C Ubiquitin-ribosomal 60S subunit protein L40B fusion protein genetic 1 1 1 Negative Genetic
EXP1 YDL121C A cargo receptor protein for Pma1p genetic 1 1 1 Negative Genetic
MRH1 YDR033W Protein that localizes primarily to the plasma membrane genetic 1 1 1 Dosage Rescue
MET17 YLR303W O-acetyl homoserine-O-acetyl serine sulfhydrylase genetic 1 1 1 Negative Genetic
RPL43B YJR094W-A Ribosomal 60S subunit protein L43B genetic 1 1 1 Negative Genetic
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 1 1 1 Positive Genetic
PHR1 YOR386W DNA photolyase involved in photoreactivation genetic 1 1 1 Negative Genetic
FCF2 YLR051C Nucleolar protein involved in the early steps of 35S rRNA processing genetic 1 1 1 Positive Genetic
PUF4 YGL014W Member of the PUF protein family genetic 1 1 1 Negative Genetic
AIM22 YJL046W Lipoate-protein ligase genetic 1 1 1 Positive Genetic
SCC4 YER147C Subunit of cohesin loading factor (Scc2p-Scc4p) genetic 1 1 1 Negative Genetic
BRL1 YHR036W Essential nuclear envelope/ER integral membrane protein genetic 1 1 1 Negative Genetic
MTC1 YJL123C Protein of unknown function that may interact with ribosomes genetic 1 1 1 Negative Genetic
MTG1 YMR097C Putative GTPase peripheral to the mitochondrial inner membrane genetic 1 1 1 Positive Genetic
GEP7 YGL057C Protein of unknown function genetic 1 1 1 Negative Genetic
NPY1 YGL067W NADH diphosphatase (pyrophosphatase) genetic 1 1 1 Negative Genetic
PMR1 YGL167C High affinity Ca2+/Mn2+ P-type ATPase genetic 1 1 1 Negative Genetic
IMP21 YIL154C Transcriptional activator involved in maintenance of ion homeostasis genetic 1 1 1 Positive Genetic
ELF1 YKL160W Transcription elongation factor with a conserved zinc finger domain genetic 1 1 1 Negative Genetic
SAC1 YKL212W Phosphatidylinositol phosphate phosphatase genetic 1 1 1 Negative Genetic
INA17 YPL099C F1F0 ATPase synthase peripheral stalk assembly factor genetic 1 1 1 Negative Genetic
RTT109 YLL002W Histone acetyltransferase genetic 1 1 1 Negative Genetic
NCW2 YLR194C GPI-anchored protein involved in cell wall remodeling genetic 1 1 1 Negative Genetic
ANY1 YMR010W Protein involved in phospholipid flippase function genetic 1 1 1 Negative Genetic
PKR1 YMR123W V-ATPase assembly factor genetic 1 1 1 Negative Genetic
POC4 YPL144W Component of a heterodimeric Poc4p-Irc25p chaperone genetic 1 1 1 Negative Genetic
RIM21 YNL294C pH sensor molecule, component of the RIM101 pathway genetic 1 1 1 Negative Genetic
GLN4 YOR168W Glutamine tRNA synthetase genetic 1 1 1 Positive Genetic
POM33 YLL023C Transmembrane nucleoporin physical 1 1 1 PCA
AHC2 YCR082W Component of the ADA histone acetyltransferase complex genetic 1 1 1 Negative Genetic
GYP7 YDL234C GTPase-activating protein for yeast Rab family members genetic 1 1 1 Negative Genetic
IMO32 YGR031W Conserved mitochondrial protein of unknown function genetic 1 1 1 Negative Genetic
LDB19 YOR322C Alpha-arrestin, Ub-ligase adaptor for Rsp5p genetic 1 1 1 Negative Genetic
PHB2 YGR231C Subunit of the prohibitin complex (Phb1p-Phb2p) genetic 1 1 1 Negative Genetic
RPL17B YJL177W Ribosomal 60S subunit protein L17B genetic 1 1 1 Negative Genetic
RPL35A YDL191W Ribosomal 60S subunit protein L35A genetic 1 1 1 Negative Genetic
RPL33B YOR234C Ribosomal 60S subunit protein L33B genetic 1 1 1 Negative Genetic
GCS1 YDL226C ADP-ribosylation factor GTPase activating protein (ARF GAP) genetic 1 1 1 Negative Genetic
AZR1 YGR224W Plasma membrane transporter of the major facilitator superfamily genetic 1 1 1 Positive Genetic
RPL35B YDL136W Ribosomal 60S subunit protein L35B genetic 1 1 1 Negative Genetic
CMK2 YOL016C Calmodulin-dependent protein kinase genetic 1 1 1 Negative Genetic
ADD37 YMR184W Protein of unknown function genetic 1 1 1 Positive Genetic
GPI12 YMR281W ER membrane protein involved in the second step of GPI anchor assembly genetic 1 1 1 Negative Genetic
DUS1 YML080W Dihydrouridine synthase genetic 1 1 1 Negative Genetic
ENT4 YLL038C Protein of unknown function genetic 1 1 1 Negative Genetic
POX1 YGL205W Fatty-acyl coenzyme A oxidase genetic 1 1 1 Negative Genetic
MNR2 YKL064W Vacuolar membrane protein required for magnesium homeostasis genetic 1 1 1 Positive Genetic
SCS22 YBL091C-A Protein involved in regulation of phospholipid metabolism genetic 1 1 1 Negative Genetic
PIB2 YGL023C Phosphatidylinositol 3-phosphate binding protein genetic 1 1 1 Positive Genetic
SDS23 YGL056C Protein involved in cell separation during budding genetic 1 1 1 Negative Genetic
HUR1 YGL168W Protein with a role in DNA repair genetic 1 1 1 Negative Genetic
SCD6 YPR129W Repressor of translation initiation genetic 1 1 1 Negative Genetic
MRX7 YNL211C Protein that associates with mitochondrial ribosome genetic 1 1 1 Negative Genetic
RPL14A YKL006W Ribosomal 60S subunit protein L14A genetic 1 1 1 Negative Genetic
ALO1 YML086C D-Arabinono-1,4-lactone oxidase genetic 1 1 1 Negative Genetic
RPP1B YDL130W Ribosomal protein P1 beta genetic 1 1 1 Negative Genetic
RBA50 YDR527W Protein involved in transcription genetic 1 1 1 Negative Genetic
NCB2 YDR397C Subunit of a heterodimeric NC2 transcription regulator complex genetic 1 1 1 Negative Genetic
RER2 YBR002C Forms the dehydrodolichyl diphosphate synthase (DDS) complex with NUS1 genetic 1 1 1 Positive Genetic
LDB18 YLL049W Component of the dynactin complex genetic 1 1 1 Positive Genetic
MEP3 YPR138C Ammonium permease of high capacity and low affinity genetic 1 1 1 Negative Genetic
GRX3 YDR098C Glutathione-dependent oxidoreductase genetic 1 1 1 Negative Genetic
ILM1 YJR118C Protein of unknown function genetic 1 1 1 Positive Genetic
RTC1 YOL138C Subunit of SEACAT, a subcomplex of the SEA complex genetic 1 1 1 Positive Genetic
MDM32 YOR147W Mitochondrial inner membrane protein with similarity to Mdm31p genetic 1 1 1 Negative Genetic
HLJ1 YMR161W Co-chaperone for Hsp40p genetic 1 1 1 Phenotypic Suppression
CHO2 YGR157W Phosphatidylethanolamine methyltransferase (PEMT) genetic 1 1 1 Negative Genetic
GPI13 YLL031C ER membrane localized phosphoryltransferase genetic 1 1 1 Negative Genetic
MOT3 YMR070W Transcriptional repressor, activator genetic 1 1 1 Positive Genetic
PET18 YCR020C Protein of unknown function genetic 1 1 1 Negative Genetic
MAK31 YCR020C-A Non-catalytic subunit of N-terminal acetyltransferase of the NatC type genetic 1 1 1 Negative Genetic
PXP1 YEL020C Peroxisomal matrix protein genetic 1 1 1 Negative Genetic
BRR6 YGL247W Essential nuclear envelope integral membrane protein genetic 1 1 1 Negative Genetic
GPC1 YGR149W Glycerophosphocholine acyltransferase (GPCAT) genetic 1 1 1 Negative Genetic
NFU1 YKL040C Protein involved in Fe-S cluster transfer to mitochondrial clients genetic 1 1 1 Positive Genetic
MTC2 YKL098W Protein of unknown function genetic 1 1 1 Negative Genetic
ISC1 YER019W Inositol phosphosphingolipid phospholipase C genetic 1 1 1 Negative Genetic
DAT1 YML113W DNA binding protein that recognizes oligo(dA).oligo(dT) tracts genetic 1 1 1 Positive Genetic
CTS1 YLR286C Endochitinase genetic 1 1 1 Positive Genetic
LCB4 YOR171C Sphingoid long-chain base kinase genetic 1 1 1 Negative Genetic
CRS5 YOR031W Copper-binding metallothionein genetic 1 1 1 Negative Genetic
ERD1 YDR414C Predicted membrane protein required for lumenal ER protein retention physical 1 1 1 PCA
ERD1 YDR414C Predicted membrane protein required for lumenal ER protein retention genetic 1 1 1 Negative Genetic
MPC1 YGL080W Highly conserved subunit of mitochondrial pyruvate carrier (MPC) genetic 1 1 1 Negative Genetic
MIX23 YBL107C Mitochondrial intermembrane space protein of unknown function genetic 1 1 1 Negative Genetic
FMP33 YJL161W Putative protein of unknown function genetic 1 1 1 Negative Genetic
MNT2 YGL257C Mannosyltransferase genetic 1 1 1 Negative Genetic
MRM2 YGL136C Mitochondrial 2' O-ribose methyltransferase genetic 1 1 1 Positive Genetic
CRD1 YDL142C Cardiolipin synthase genetic 1 1 1 Positive Genetic
CDC1 YDR182W Putative mannose-ethanolamine phosphate phosphodiesterase genetic 1 1 1 Positive Genetic
DIT2 YDR402C N-formyltyrosine oxidase genetic 1 1 1 Positive Genetic
DCV1 YFR012W Protein of unknown function genetic 1 1 1 Negative Genetic
MOD5 YOR274W Delta 2-isopentenyl pyrophosphate:tRNA isopentenyl transferase genetic 1 1 1 Positive Genetic
HEM25 YDL119C Mitochondrial glycine transporter genetic 1 1 1 Negative Genetic
CQD2 YLR253W Mitochondrial protein involved in lipid homeostasis genetic 1 1 1 Negative Genetic
RPL24B YGR148C Ribosomal 60S subunit protein L24B genetic 1 1 1 Negative Genetic
RBK1 YCR036W Ribokinase, phosphorylates ribose to ribose-5-phosphate genetic 1 1 1 Negative Genetic
PMP3 YDR276C Small plasma membrane protein genetic 1 1 1 Positive Genetic
ERD2 YBL040C HDEL receptor genetic 1 1 1 Dosage Rescue
PER1 YCR044C Protein of the endoplasmic reticulum genetic 1 1 1 Positive Genetic
ALG8 YOR067C Glucosyl transferase genetic 1 1 1 Positive Genetic
GCV1 YDR019C T subunit of the mitochondrial glycine decarboxylase complex genetic 1 1 1 Negative Genetic
NPR3 YHL023C Subunit of the Iml1p/SEACIT complex genetic 1 1 1 Negative Genetic
MRX19 YDL183C Protein that may form an active mitochondrial KHE system genetic 1 1 1 Positive Genetic
PTH1 YHR189W One of two mitochondrially-localized peptidyl-tRNA hydrolases genetic 1 1 1 Negative Genetic
RPS30B YOR182C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
RCF1 YML030W Cytochrome c oxidase subunit genetic 1 1 1 Positive Genetic
SSA1 YAL005C ATPase involved in protein folding and NLS-directed nuclear transport physical 1 1 1 Affinity Capture-MS
SEC12 YNR026C Guanine nucleotide exchange factor (GEF) physical 1 1 1 Affinity Capture-MS
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone genetic 1 1 1 Negative Genetic
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p physical 1 1 1 Affinity Capture-MS
TOM22 YNL131W Component of the TOM (Translocase of Outer Membrane) complex physical 1 1 1 Affinity Capture-MS
SEC61 YLR378C Conserved ER protein translocation channel physical 1 1 1 Affinity Capture-MS
SEC61 YLR378C Conserved ER protein translocation channel genetic 1 1 1 Negative Genetic
SHR3 YDL212W Endoplasmic reticulum packaging chaperone genetic 1 1 1 Dosage Rescue
SEC7 YDR170C Guanine nucleotide exchange factor (GEF) for ADP ribosylation factors genetic 1 1 1 Synthetic Growth Defect
SWE1 YJL187C Protein kinase that regulates the G2/M transition genetic 1 1 1 Dosage Growth Defect
YCK2 YNL154C Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform genetic 1 1 1 Synthetic Growth Defect
WBP1 YEL002C Beta subunit of the oligosaccharyl transferase glycoprotein complex genetic 1 1 1 Positive Genetic
TUB2 YFL037W Beta-tubulin genetic 1 1 1 Positive Genetic
UTP8 YGR128C Nucleolar protein required for export of tRNAs from the nucleus genetic 1 1 1 Positive Genetic
UTP9 YHR196W Nucleolar protein genetic 1 1 1 Positive Genetic
UTP13 YLR222C Nucleolar protein genetic 1 1 1 Positive Genetic
UTP15 YMR093W Nucleolar protein genetic 1 1 1 Positive Genetic
YTH1 YPR107C Essential RNA-binding component of cleavage and polyadenylation factor genetic 1 1 1 Positive Genetic
TEF2 YBR118W Translational elongation factor EF-1 alpha genetic 1 1 1 Positive Genetic
SSH1 YBR283C Subunit of the Ssh1 translocon complex genetic 1 1 1 Positive Genetic
SNF5 YBR289W Subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Positive Genetic
YIH1 YCR059C Negative regulator of eIF2 kinase Gcn2p genetic 1 1 1 Positive Genetic
YCR090C YCR090C Putative protein of unknown function genetic 1 1 1 Positive Genetic
WHI4 YDL224C Putative RNA binding protein genetic 1 1 1 Positive Genetic
VPS60 YDR486C Protein involved in late endosome to vacuole transport genetic 1 1 1 Positive Genetic
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p) genetic 1 1 1 Positive Genetic
YFL051C YFL051C Putative protein of unknown function genetic 1 1 1 Positive Genetic
SER2 YGR208W Phosphoserine phosphatase of the phosphoglycerate pathway genetic 1 1 1 Positive Genetic
TPM2 YIL138C Minor isoform of tropomyosin genetic 1 1 1 Positive Genetic
YLR278C YLR278C Zinc-cluster protein genetic 1 1 1 Positive Genetic
VIP1 YLR410W Bifunctional inositol pyrophosphate kinase and phosphatase genetic 1 1 1 Positive Genetic
SRC1 YML034W Inner nuclear membrane protein genetic 1 1 1 Positive Genetic
VPS9 YML097C Guanine nucleotide exchange factor (GEF) and ubiquitin receptor genetic 1 1 1 Positive Genetic
SUB1 YMR039C Transcriptional regulator genetic 1 1 1 Positive Genetic
YHM2 YMR241W Citrate and oxoglutarate carrier protein genetic 1 1 1 Positive Genetic
TAT2 YOL020W High affinity tryptophan and tyrosine permease genetic 1 1 1 Positive Genetic
TGL5 YOR081C Bifunctional triacylglycerol lipase and LPA acyltransferase genetic 1 1 1 Positive Genetic
SGF11 YPL047W Integral subunit of SAGA histone acetyltransferase complex genetic 1 1 1 Positive Genetic
YAR1 YPL239W Nucleocytoplasmic shuttling assembly chaperone genetic 1 1 1 Positive Genetic
YPL247C YPL247C Putative protein of unknown function genetic 1 1 1 Positive Genetic
TIP41 YPR040W Tap42p-interacting protein genetic 1 1 1 Positive Genetic
SKI3 YPR189W Ski complex component and TPR protein genetic 1 1 1 Positive Genetic
STP22 YCL008C Component of the ESCRT-I complex genetic 1 1 1 Positive Genetic
YCR024C-B YCR024C-B Putative protein of unknown function genetic 1 1 1 Positive Genetic
SWF1 YDR126W Palmitoyltransferase that acts on transmembrane proteins genetic 1 1 1 Positive Genetic
SSD1 YDR293C Translational repressor genetic 1 1 1 Positive Genetic
VAC8 YEL013W Vacuole-specific Myo2p receptor genetic 1 1 1 Positive Genetic
YHR078W YHR078W High osmolarity-regulated gene of unknown function genetic 1 1 1 Positive Genetic
UBR2 YLR024C Cytoplasmic ubiquitin-protein ligase (E3) genetic 1 1 1 Positive Genetic
SIP5 YMR140W Protein of unknown function genetic 1 1 1 Positive Genetic
YOR316C-A YOR316C-A Putative protein of unknown function genetic 1 1 1 Positive Genetic
STU1 YBL034C Microtubule plus-end-tracking non-motor protein genetic 1 1 1 Negative Genetic
TAF5 YBR198C Subunit (90 kDa) of TFIID and SAGA complexes genetic 1 1 1 Negative Genetic
SEC26 YDR238C Essential beta-coat protein of the COPI coatomer genetic 1 1 1 Negative Genetic
TFC6 YDR362C Subunit of RNA polymerase III transcription initiation factor complex genetic 1 1 1 Negative Genetic
TLG1 YDR468C Essential t-SNARE that mediates fusion of vesicles with the late Golgi genetic 1 1 1 Negative Genetic
SMC1 YFL008W Subunit of the multiprotein cohesin complex genetic 1 1 1 Negative Genetic
TFG2 YGR005C TFIIF (Transcription Factor II) middle subunit genetic 1 1 1 Negative Genetic
TFC4 YGR047C Subunit of RNA polymerase III transcription initiation factor complex genetic 1 1 1 Negative Genetic
TFG1 YGR186W TFIIF (Transcription Factor II) largest subunit genetic 1 1 1 Negative Genetic
TAF1 YGR274C TFIID subunit, involved in RNA pol II transcription initiation genetic 1 1 1 Negative Genetic
URA6 YKL024C Uridylate kinase genetic 1 1 1 Negative Genetic
TFA1 YKL028W TFIIE large subunit genetic 1 1 1 Negative Genetic
SPC42 YKL042W Central plaque component of spindle pole body (SPB) genetic 1 1 1 Negative Genetic
SRP102 YKL154W Signal recognition particle (SRP) receptor beta subunit genetic 1 1 1 Negative Genetic
YKT6 YKL196C Vesicle membrane protein (v-SNARE) with acyltransferase activity genetic 1 1 1 Negative Genetic
TOR2 YKL203C PIK-related protein kinase and rapamycin target genetic 1 1 1 Negative Genetic
TFA2 YKR062W TFIIE small subunit genetic 1 1 1 Negative Genetic
SSL1 YLR005W Subunit of the core form of RNA polymerase transcription factor TFIIH genetic 1 1 1 Negative Genetic
SMC4 YLR086W Subunit of the condensin complex genetic 1 1 1 Negative Genetic
SMD2 YLR275W Core Sm protein Sm D2 genetic 1 1 1 Negative Genetic
TAF11 YML015C TFIID subunit (40 kDa) genetic 1 1 1 Negative Genetic
TAF13 YML098W TFIID subunit (19 kDa) genetic 1 1 1 Negative Genetic
TAF8 YML114C TFIID subunit (65 kDa) genetic 1 1 1 Negative Genetic
TIF34 YMR146C eIF3i subunit of the eukaryotic translation initiation factor 3 (eIF3) genetic 1 1 1 Negative Genetic
TAF9 YMR236W Subunit (17 kDa) of TFIID and SAGA complexes genetic 1 1 1 Negative Genetic
SSU72 YNL222W Phosphatase and transcription/RNA-processing factor genetic 1 1 1 Negative Genetic
TSC3 YBR058C-A Protein that stimulates the activity of serine palmitoyltransferase genetic 1 1 1 Negative Genetic
TRS20 YBR254C Core component of transport protein particle (TRAPP) complexes I-III genetic 1 1 1 Negative Genetic
SNU23 YDL098C Component of the U4/U6.U5 snRNP complex genetic 1 1 1 Negative Genetic
STN1 YDR082W Telomere end-binding and capping protein genetic 1 1 1 Negative Genetic
SSS1 YDR086C Subunit of the Sec61p translocation complex (Sec61p-Sss1p-Sbh1p) genetic 1 1 1 Negative Genetic
TCP1 YDR212W Alpha subunit of chaperonin-containing T-complex genetic 1 1 1 Negative Genetic
SRP101 YDR292C Signal recognition particle (SRP) receptor alpha subunit genetic 1 1 1 Negative Genetic
TFB1 YDR311W Subunit of TFIIH and nucleotide excision repair factor 3 complexes genetic 1 1 1 Negative Genetic
SPT15 YER148W TATA-binding protein (TBP) genetic 1 1 1 Negative Genetic
YJU2 YKL095W Essential protein required for pre-mRNA splicing genetic 1 1 1 Negative Genetic
VTI1 YMR197C Protein involved in cis-Golgi membrane traffic genetic 1 1 1 Negative Genetic
SMC5 YOL034W Subunit of the SMC5-SMC6 complex genetic 1 1 1 Negative Genetic
SGT1 YOR057W Cochaperone protein genetic 1 1 1 Negative Genetic
WRS1 YOL097C Cytoplasmic tryptophanyl-tRNA synthetase genetic 1 1 1 Negative Genetic
TPT1 YOL102C tRNA 2'-phosphotransferase that catalyzes final step in tRNA splicing genetic 1 1 1 Negative Genetic
SME1 YOR159C Core Sm protein Sm E genetic 1 1 1 Negative Genetic
TOA1 YOR194C TFIIA large subunit genetic 1 1 1 Negative Genetic
TFC8 YPL007C Subunit of RNA polymerase III transcription initiation factor complex genetic 1 1 1 Negative Genetic
TAF3 YPL011C TFIID subunit (47 kDa) genetic 1 1 1 Negative Genetic
TFB4 YPR056W Subunit of TFIIH complex genetic 1 1 1 Negative Genetic
SGV1 YPR161C Cyclin (Bur2p)-dependent protein kinase genetic 1 1 1 Negative Genetic
SMX3 YPR182W Core Sm protein Sm F genetic 1 1 1 Negative Genetic
YBL036C YBL036C Putative non-specific single-domain racemase genetic 1 1 1 Negative Genetic
UBP14 YBR058C Ubiquitin-specific protease genetic 1 1 1 Negative Genetic
TEC1 YBR083W Transcription factor targeting filamentation genes and Ty1 expression genetic 1 1 1 Negative Genetic
YBR284W YBR284W Putative metallo-dependent hydrolase superfamily protein genetic 1 1 1 Negative Genetic
TMA17 YDL110C Regulatory gamma subunit of fatty acid synthase (FAS) genetic 1 1 1 Negative Genetic
UGA3 YDL170W Transcriptional activator for GABA-dependent induction of GABA genes genetic 1 1 1 Negative Genetic
TRS85 YDR108W Component of transport protein particle (TRAPP) complex III genetic 1 1 1 Negative Genetic
SND1 YDR186C Protein involved in SRP-independent targeting of substrates to the ER genetic 1 1 1 Negative Genetic
YDR248C YDR248C Putative gluconokinase genetic 1 1 1 Negative Genetic
SWA2 YDR320C Auxilin-like protein involved in vesicular transport genetic 1 1 1 Negative Genetic
XRS2 YDR369C FHA domain-containing component of the Mre11 complex genetic 1 1 1 Negative Genetic
SNF1 YDR477W AMP-activated S/T protein kinase genetic 1 1 1 Negative Genetic
YER084W YER084W Protein of unknown function genetic 1 1 1 Negative Genetic
TAD1 YGL243W tRNA-specific adenosine deaminase genetic 1 1 1 Negative Genetic
YHR022C YHR022C Putative protein of unknown function genetic 1 1 1 Negative Genetic
SOL3 YHR163W 6-phosphogluconolactonase genetic 1 1 1 Negative Genetic
SVP26 YHR181W ER exit adaptor for Golgi mannosyltransferases genetic 1 1 1 Negative Genetic
UBP7 YIL156W Ubiquitin-specific protease that cleaves ubiquitin-protein fusions genetic 1 1 1 Negative Genetic
SOA1 YIL166C Sulfonate and inorganic sulfur transporter genetic 1 1 1 Negative Genetic
SYS1 YJL004C Integral membrane protein of the Golgi genetic 1 1 1 Negative Genetic
VPS53 YJL029C Component of the GARP (Golgi-associated retrograde protein) complex genetic 1 1 1 Negative Genetic
UBX6 YJL048C UBX (ubiquitin regulatory X) domain-containing protein genetic 1 1 1 Negative Genetic
YJL213W YJL213W Protein of unknown function that may interact with ribosomes genetic 1 1 1 Negative Genetic
TMA22 YJR014W Protein of unknown function genetic 1 1 1 Negative Genetic
TMA19 YKL056C Protein that associates with ribosomes genetic 1 1 1 Negative Genetic
YKL069W YKL069W Methionine-R-sulfoxide reductase genetic 1 1 1 Negative Genetic
STB6 YKL072W Protein that binds Sin3p in a two-hybrid assay genetic 1 1 1 Negative Genetic
TRK2 YKR050W Component of the Trk1p-Trk2p potassium transport system genetic 1 1 1 Negative Genetic
YCT1 YLL055W High-affinity cysteine-specific transporter genetic 1 1 1 Negative Genetic
SEC22 YLR268W R-SNARE protein genetic 1 1 1 Negative Genetic
SWC7 YLR385C Protein of unknown function genetic 1 1 1 Negative Genetic
VAC14 YLR386W Enzyme regulator genetic 1 1 1 Negative Genetic
SEI1 YLR404W Seipin involved in lipid droplet (LD) assembly genetic 1 1 1 Negative Genetic
YML002W YML002W Putative protein of unknown function genetic 1 1 1 Negative Genetic
TRM732 YMR259C Protein involved in 2'-O-methylation of C32 of substrate tRNAs genetic 1 1 1 Negative Genetic
YMR317W YMR317W Putative protein of unknown function genetic 1 1 1 Negative Genetic
TLG2 YOL018C Syntaxin-like t-SNARE genetic 1 1 1 Negative Genetic
TRM10 YOL093W tRNA methyltransferase genetic 1 1 1 Negative Genetic
WHI5 YOR083W Repressor of G1 transcription genetic 1 1 1 Negative Genetic
VIK1 YPL253C Protein that forms a kinesin-14 heterodimeric motor with Kar3p genetic 1 1 1 Negative Genetic
SWD1 YAR003W Subunit of the COMPASS (Set1C) complex genetic 1 1 1 Negative Genetic
STE50 YCL032W Adaptor protein for various signaling pathways genetic 1 1 1 Negative Genetic
VPS41 YDR080W Subunit of the HOPS endocytic tethering complex genetic 1 1 1 Negative Genetic
UBP6 YFR010W Ubiquitin-specific protease genetic 1 1 1 Negative Genetic
YTA7 YGR270W Chromatin-binding ATPase that regulates histone gene expression genetic 1 1 1 Negative Genetic
SYC1 YOR179C Subunit of the APT subcomplex of cleavage and polyadenylation factor genetic 1 1 1 Negative Genetic
THP3 YPR045C Protein that may have a role in transcription elongation genetic 1 1 1 Negative Genetic
SPO7 YAL009W Putative regulatory subunit of Nem1p-Spo7p phosphatase holoenzyme genetic 1 1 1 Negative Genetic
YAR035C-A YAR035C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
SRO77 YBL106C Protein with roles in exocytosis and cation homeostasis genetic 1 1 1 Negative Genetic
YBR071W YBR071W Protein of unknown function found in the cytoplasm and bud neck genetic 1 1 1 Negative Genetic
SIF2 YBR103W WD40 repeat-containing subunit of Set3C histone deacetylase complex genetic 1 1 1 Negative Genetic
TKL2 YBR117C Transketolase genetic 1 1 1 Negative Genetic
YBR221W-A YBR221W-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
YDL144C YDL144C Protein of unknown function genetic 1 1 1 Negative Genetic
SOK1 YDR006C Protein of unknown function genetic 1 1 1 Negative Genetic
TMA64 YDR117C Protein of unknown function that associates with ribosomes genetic 1 1 1 Negative Genetic
SEM1 YDR363W-A 19S proteasome regulatory particle lid subcomplex component genetic 1 1 1 Negative Genetic
SPT2 YER161C Protein involved in negative regulation of transcription genetic 1 1 1 Negative Genetic
ZNF1 YFL052W Zinc cluster transcription factor that regulates respiratory growth genetic 1 1 1 Negative Genetic
SOH1 YGL127C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
YGL185C YGL185C Putative protein with sequence similar to hydroxyacid dehydrogenases genetic 1 1 1 Negative Genetic
UGA1 YGR019W Gamma-aminobutyrate (GABA) transaminase genetic 1 1 1 Negative Genetic
TRA1 YHR099W Subunit of SAGA and NuA4 histone acetyltransferase complexes genetic 1 1 1 Negative Genetic
SEC28 YIL076W Epsilon-COP subunit of the coatomer genetic 1 1 1 Negative Genetic
YIR018C-A YIR018C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
SNX4 YJL036W Sorting nexin genetic 1 1 1 Negative Genetic
YJL136W-A YJL136W-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
SEG2 YKL105C Eisosome component genetic 1 1 1 Negative Genetic
SLX4 YLR135W Endonuclease involved in processing DNA genetic 1 1 1 Negative Genetic
YLR361C-A YLR361C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
YMR181C YMR181C Protein of unknown function genetic 1 1 1 Negative Genetic
YME2 YMR302C Integral inner mitochondrial membrane protein genetic 1 1 1 Negative Genetic
SLA2 YNL243W Adaptor protein that links actin to clathrin and endocytosis genetic 1 1 1 Negative Genetic
SNO2 YNL334C Protein of unknown function genetic 1 1 1 Negative Genetic
SIN3 YOL004W Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 1 1 1 Negative Genetic
THI20 YOL055C Trifunctional enzyme of thiamine biosynthesis, degradation and salvage genetic 1 1 1 Negative Genetic
YOR011W-A YOR011W-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
TOM6 YOR045W Component of the TOM (translocase of outer membrane) complex genetic 1 1 1 Negative Genetic
YOR192C-C YOR192C-C Putative protein of unknown function genetic 1 1 1 Negative Genetic
YPR084W YPR084W Putative protein of unknown function genetic 1 1 1 Negative Genetic
SNT309 YPR101W Member of the NineTeen Complex (NTC) genetic 1 1 1 Negative Genetic
USO1 YDL058W Essential protein involved in vesicle-mediated ER to Golgi transport genetic 1 1 1 Negative Genetic
SEC53 YFL045C Phosphomannomutase genetic 1 1 1 Positive Genetic
SPC3 YLR066W Subunit of signal peptidase complex genetic 1 1 1 Positive Genetic
UFD4 YKL010C Ubiquitin-protein ligase (E3) genetic 1 1 1 Negative Genetic
UBX4 YMR067C UBX domain-containing protein that interacts with Cdc48p genetic 1 1 1 Negative Genetic
SPC105 YGL093W Subunit of a kinetochore-microtubule binding complex genetic 1 1 1 Negative Genetic
SEC59 YMR013C Dolichol kinase genetic 1 1 1 Negative Genetic
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 1 1 1 Positive Genetic
CWP1 YKL096W Cell wall mannoprotein that localizes to birth scars of daughter cells genetic 1 1 1 Positive Genetic
IRC10 YOL015W Protein of unknown function genetic 1 1 1 Positive Genetic
MME1 YMR166C Transporter of the mitochondrial inner membrane that exports magnesium genetic 1 1 1 Negative Genetic
DBR1 YKL149C RNA lariat debranching enzyme genetic 1 1 1 Positive Genetic
REX3 YLR107W RNA exonuclease genetic 1 1 1 Negative Genetic
PET20 YPL159C Mitochondrial protein genetic 1 1 1 Negative Genetic
MTC4 YBR255W Protein of unknown function genetic 1 1 1 Negative Genetic
PRM5 YIL117C Pheromone-regulated protein, predicted to have 1 transmembrane segment genetic 1 1 1 Negative Genetic
IMA5 YJL216C Alpha-glucosidase genetic 1 1 1 Negative Genetic
MAY24 YPR153W Peripheral ER membrane protein genetic 1 1 1 Negative Genetic
PRM6 YML047C Potassium transporter that mediates K+ influx genetic 1 1 1 Negative Genetic
RKM2 YDR198C Ribosomal protein lysine methyltransferase genetic 1 1 1 Negative Genetic
MTC6 YHR151C Protein of unknown function genetic 1 1 1 Negative Genetic
ECM8 YBR076W Non-essential protein of unknown function genetic 1 1 1 Positive Genetic
FYV12 YOR183W Protein of unknown function genetic 1 1 1 Positive Genetic
NIT1 YIL164C Nitrilase genetic 1 1 1 Negative Genetic
RRT8 YOL048C Protein involved in spore wall assembly genetic 1 1 1 Negative Genetic
MIN3 YMR182W-A Mitochondrial protein of unknown function genetic 1 1 1 Negative Genetic