Standard name Systematic name Name description Description
PRP9 YDL030W Subunit of the SF3a splicing factor complex Subunit of the SF3a splicing factor complex; required for spliceosome assembly; acts after the formation of the U1 snRNP-pre-mRNA complex
Visualize the interactome of PRP9
Links to external databases:
SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Mito 0.173 0.141 0.429
Nucleolus 0.058 NaN NaN
Nucleus 0.955 0.934 0.893

GFP localization & abundance

GFP localization GFP abundance
nucleus 3920

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
PRP9 3 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
PRP21 YJL203W Subunit of the SF3a splicing factor complex physical 11 3 10 Affinity Capture-MS, Reconstituted Complex, Two-hybrid, Two-hybrid, Reconstituted Complex, Affinity Capture-MS, Two-hybrid, Two-hybrid, Affinity Capture-MS, Affinity Capture-MS, Two-hybrid
PRP11 YDL043C Subunit of the SF3a splicing factor complex physical 4 2 4 Reconstituted Complex, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS
PRP21 YJL203W Subunit of the SF3a splicing factor complex genetic 3 3 3 Synthetic Rescue, Synthetic Lethality, Negative Genetic
PRP19 YLL036C Splicing factor associated with the spliceosome physical 3 2 3 Affinity Capture-MS, Co-purification, Affinity Capture-MS
CBC2 YPL178W Small subunit of the heterodimeric cap binding complex with Sto1p physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
LEA1 YPL213W Component of U2 snRNP complex physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
ESS1 YJR017C Peptidylprolyl-cis/trans-isomerase (PPIase) genetic 3 2 1 Positive Genetic, Negative Genetic, Negative Genetic
ELG1 YOR144C Subunit of an alternative replication factor C complex genetic 2 2 2 Synthetic Lethality, Positive Genetic
PRP2 YNR011C RNA-dependent DExD/H-box ATPase genetic 2 2 2 Negative Genetic, Synthetic Rescue
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 2 2 2 Negative Genetic, Positive Genetic
BRR2 YER172C RNA-dependent ATPase RNA helicase (DEIH box) physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
PRP8 YHR165C Component of U4/U6-U5 snRNP complex physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
CUS1 YMR240C Protein required for assembly of U2 snRNP into the spliceosome physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SMD1 YGR074W Core Sm protein Sm D1 physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SPP381 YBR152W mRNA splicing factor, component of U4/U6.U5 tri-snRNP physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SMB1 YER029C Core Sm protein Sm B physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SNU66 YOR308C Component of the U4/U6.U5 snRNP complex physical 2 2 1 Affinity Capture-MS, Affinity Capture-Western
SMD2 YLR275W Core Sm protein Sm D2 genetic 2 2 1 Positive Genetic, Negative Genetic
RNT1 YMR239C Nuclear dsRNA-specific ribonuclease (RNase III) genetic 2 2 1 Positive Genetic, Negative Genetic
RPN8 YOR261C Essential non-ATPase regulatory subunit of the 26S proteasome genetic 2 2 1 Positive Genetic, Negative Genetic
BET1 YIL004C Type II membrane protein required for vesicular transport genetic 2 2 1 Positive Genetic, Negative Genetic
FCP1 YMR277W Carboxy-terminal domain (CTD) phosphatase genetic 2 2 1 Positive Genetic, Negative Genetic
MUD1 YBR119W U1 snRNP A protein genetic 2 1 1 Negative Genetic, Negative Genetic
NAM8 YHR086W RNA binding protein, component of the U1 snRNP protein genetic 2 1 1 Negative Genetic, Negative Genetic
SNU66 YOR308C Component of the U4/U6.U5 snRNP complex genetic 2 1 1 Negative Genetic, Negative Genetic
SEC22 YLR268W R-SNARE protein genetic 2 1 1 Negative Genetic, Negative Genetic
REX3 YLR107W RNA exonuclease genetic 2 1 1 Negative Genetic, Negative Genetic
BRR1 YPR057W snRNP protein component of spliceosomal snRNPs genetic 2 1 1 Negative Genetic, Negative Genetic
BUD13 YGL174W Subunit of the RES complex genetic 2 1 1 Negative Genetic, Negative Genetic
IST3 YIR005W Component of the U2 snRNP genetic 2 1 1 Negative Genetic, Negative Genetic
CDC27 YBL084C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 2 1 1 Negative Genetic, Negative Genetic
FYV12 YOR183W Protein of unknown function genetic 2 1 1 Negative Genetic, Negative Genetic
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
SWI5 YDR146C Transcription factor that recruits Mediator and Swi/Snf complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CEF1 YMR213W Essential splicing factor physical 1 1 1 Affinity Capture-MS
CWC25 YNL245C Splicing factor required for the first step of pre-mRNA splicing genetic 1 1 1 Negative Genetic
CTF19 YPL018W Outer kinetochore protein, needed for accurate chromosome segregation physical 1 1 1 Two-hybrid
NSL1 YPL233W Essential component of the MIND kinetochore complex genetic 1 1 1 Negative Genetic
POB3 YML069W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) genetic 1 1 1 Negative Genetic
NSE1 YLR007W Component of the SMC5-SMC6 complex genetic 1 1 1 Negative Genetic
NSE3 YDR288W Component of the SMC5-SMC6 complex genetic 1 1 1 Negative Genetic
BFR2 YDR299W Component of the SSU and 90S preribosomes genetic 1 1 1 Negative Genetic
ESF1 YDR365C Nucleolar protein involved in pre-rRNA processing genetic 1 1 1 Negative Genetic
HSP60 YLR259C Tetradecameric mitochondrial chaperonin genetic 1 1 1 Negative Genetic
BRX1 YOL077C Nucleolar protein genetic 1 1 1 Negative Genetic
HAS1 YMR290C ATP-dependent RNA helicase genetic 1 1 1 Negative Genetic
MAK16 YAL025C Essential nuclear protein genetic 1 1 1 Negative Genetic
NOG1 YPL093W Putative GTPase genetic 1 1 1 Negative Genetic
NOP2 YNL061W rRNA m5C methyltransferase genetic 1 1 1 Negative Genetic
POP1 YNL221C Subunit of RNase MRP, nuclear RNase P and telomerase complexes genetic 1 1 1 Negative Genetic
POP5 YAL033W Subunit of both RNase MRP and nuclear RNase P genetic 1 1 1 Negative Genetic
BRR2 YER172C RNA-dependent ATPase RNA helicase (DEIH box) genetic 1 1 1 Negative Genetic
PRP46 YPL151C Member of the NineTeen Complex (NTC) genetic 1 1 1 Negative Genetic
NSE5 YML023C Component of the SMC5-SMC6 complex genetic 1 1 1 Negative Genetic
NUG1 YER006W GTPase that associates with nuclear 60S pre-ribosomes genetic 1 1 1 Negative Genetic
POL5 YEL055C Protein involved in 60S assembly and pre-40S AFs recycling genetic 1 1 1 Negative Genetic
NOP58 YOR310C Protein involved in producing mature rRNAs and snoRNAs genetic 1 1 1 Negative Genetic
PAT1 YCR077C Deadenylation-dependent mRNA-decapping factor genetic 1 1 1 Positive Genetic
CSL4 YNL232W Exosome non-catalytic core component genetic 1 1 1 Positive Genetic
ARP9 YMR033W Component of both the SWI/SNF and RSC chromatin remodeling complexes genetic 1 1 1 Negative Genetic
MUD1 YBR119W U1 snRNP A protein physical 1 1 1 Affinity Capture-MS
PRP40 YKL012W U1 snRNP protein involved in splicing genetic 1 1 1 Negative Genetic
NIP1 YMR309C eIF3c subunit of the eukaryotic translation initiation factor 3 (eIF3) genetic 1 1 1 Negative Genetic
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 1 1 1 Negative Genetic
PRE6 YOL038W Alpha 4 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
KAP104 YBR017C Transportin or cytosolic karyopherin beta 2 genetic 1 1 1 Positive Genetic
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-MS
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein genetic 1 1 1 Negative Genetic
APC1 YNL172W Largest subunit of the Anaphase-Promoting Complex/Cyclosome genetic 1 1 1 Negative Genetic
ARC15 YIL062C Subunit of the ARP2/3 complex genetic 1 1 1 Negative Genetic
ARC35 YNR035C Subunit of the ARP2/3 complex genetic 1 1 1 Negative Genetic
ARP2 YDL029W Essential component of the Arp2/3 complex genetic 1 1 1 Synthetic Lethality
BDF1 YLR399C BET family transcriptional regulator genetic 1 1 1 Negative Genetic
ASC1 YMR116C G-protein beta subunit and guanine dissociation inhibitor for Gpa2p physical 1 1 1 Affinity Capture-MS
ASC1 YMR116C G-protein beta subunit and guanine dissociation inhibitor for Gpa2p genetic 1 1 1 Negative Genetic
BUD20 YLR074C C2H2-type zinc finger protein required for ribosome assembly genetic 1 1 1 Positive Genetic
AIM21 YIR003W Subunit of a complex that associates with actin filaments genetic 1 1 1 Negative Genetic
CDC14 YFR028C Protein phosphatase required for mitotic exit genetic 1 1 1 Negative Genetic
CDC24 YAL041W Guanine nucleotide exchange factor (GEF) for Cdc42p genetic 1 1 1 Negative Genetic
CDC10 YCR002C Component of the septin ring, required for cytokinesis genetic 1 1 1 Negative Genetic
CDC12 YHR107C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Synthetic Growth Defect
NOG2 YNR053C Putative GTPase genetic 1 1 1 Negative Genetic
CUS1 YMR240C Protein required for assembly of U2 snRNP into the spliceosome genetic 1 1 1 Negative Genetic
DCP1 YOL149W Subunit of the Dcp1p-Dcp2p decapping enzyme complex genetic 1 1 1 Positive Genetic
DCP2 YNL118C Catalytic subunit of Dcp1p-Dcp2p decapping enzyme complex genetic 1 1 1 Negative Genetic
DNA2 YHR164C ATP-dependent 5'-flap endonuclease and DNA helicase genetic 1 1 1 Negative Genetic
EMG1 YLR186W Methyltransferase for rRNA genetic 1 1 1 Negative Genetic
ERO1 YML130C Thiol oxidase required for oxidative protein folding in the ER genetic 1 1 1 Negative Genetic
CTO1 YCR015C Protein required for cold tolerance genetic 1 1 1 Positive Genetic
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
HRP1 YOL123W Subunit of cleavage factor I genetic 1 1 1 Negative Genetic
IML3 YBR107C Outer kinetochore protein and component of the Ctf19 complex genetic 1 1 1 Negative Genetic
LAS17 YOR181W Actin assembly factor genetic 1 1 1 Negative Genetic
LSM2 YBL026W Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
LSM4 YER112W Lsm (Like Sm) protein physical 1 1 1 Affinity Capture-MS
LSM7 YNL147W Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
MAK5 YBR142W Essential nucleolar protein genetic 1 1 1 Negative Genetic
MED11 YMR112C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Positive Genetic
MED6 YHR058C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
HRR25 YPL204W Conserved casein kinase, monopolin subunit genetic 1 1 1 Negative Genetic
MRM1 YOR201C Ribose methyltransferase genetic 1 1 1 Negative Genetic
MRPL25 YGR076C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
ATG3 YNR007C E2-like enzyme genetic 1 1 1 Negative Genetic
CMD1 YBR109C Calmodulin genetic 1 1 1 Negative Genetic
GIN4 YDR507C Protein kinase involved in bud growth and assembly of the septin ring genetic 1 1 1 Negative Genetic
INO80 YGL150C Nucleosome spacing factor genetic 1 1 1 Negative Genetic
FAS2 YPL231W Alpha subunit of fatty acid synthetase genetic 1 1 1 Negative Genetic
OST1 YJL002C Alpha subunit of the oligosaccharyltransferase complex of the ER lumen genetic 1 1 1 Negative Genetic
HTA1 YDR225W Histone H2A genetic 1 1 1 Negative Genetic
PRP28 YDR243C Pre-mRNA splicing factor genetic 1 1 1 Negative Genetic
PRP4 YPR178W Splicing factor genetic 1 1 1 Negative Genetic
GCN20 YFR009W Positive regulator of the Gcn2p kinase activity genetic 1 1 1 Negative Genetic
MED8 YBR193C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
DEP1 YAL013W Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
PHO23 YNL097C Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
CDC6 YJL194W Essential ATP-binding protein required for DNA replication genetic 1 1 1 Negative Genetic
NUP120 YKL057C Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
CCT2 YIL142W Subunit beta of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Negative Genetic
SME1 YOR159C Core Sm protein Sm E physical 1 1 1 Affinity Capture-MS
SME1 YOR159C Core Sm protein Sm E genetic 1 1 1 Negative Genetic
SMX2 YFL017W-A Core Sm protein Sm G physical 1 1 1 Affinity Capture-MS
SMX3 YPR182W Core Sm protein Sm F physical 1 1 1 Affinity Capture-MS
SMX3 YPR182W Core Sm protein Sm F genetic 1 1 1 Negative Genetic
SPP381 YBR152W mRNA splicing factor, component of U4/U6.U5 tri-snRNP genetic 1 1 1 Negative Genetic
SLX5 YDL013W Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex physical 1 1 1 Two-hybrid
TAF4 YMR005W TFIID subunit (48 kDa) physical 1 1 1 Two-hybrid
VPS72 YDR485C Htz1p-binding component of the SWR1 complex physical 1 1 1 Two-hybrid
VPS72 YDR485C Htz1p-binding component of the SWR1 complex genetic 1 1 1 Negative Genetic
RSE1 YML049C Protein involved in pre-mRNA splicing physical 1 1 1 Two-hybrid
RSE1 YML049C Protein involved in pre-mRNA splicing genetic 1 1 1 Negative Genetic
ULS1 YOR191W Swi2/Snf2-related translocase, SUMO-Targeted Ubiquitin Ligase (STUbL) physical 1 1 1 Two-hybrid
SEM1 YDR363W-A 19S proteasome regulatory particle lid subcomplex component physical 1 1 1 Affinity Capture-MS
SEM1 YDR363W-A 19S proteasome regulatory particle lid subcomplex component genetic 1 1 1 Positive Genetic
RPN12 YFR052W Subunit of the 19S regulatory particle of the 26S proteasome lid physical 1 1 1 Affinity Capture-MS
RPN12 YFR052W Subunit of the 19S regulatory particle of the 26S proteasome lid genetic 1 1 1 Positive Genetic
SMD3 YLR147C Core Sm protein Sm D3 physical 1 1 1 Affinity Capture-MS
SCM3 YDL139C Nonhistone component of centromeric chromatin physical 1 1 1 Two-hybrid
SKP1 YDR328C Evolutionarily conserved kinetochore protein physical 1 1 1 Two-hybrid
SPC25 YER018C Component of the kinetochore-associated Ndc80 complex physical 1 1 1 Two-hybrid
SPO12 YHR152W Nucleolar protein of unknown function physical 1 1 1 Two-hybrid
STO1 YMR125W Large subunit of the nuclear mRNA cap-binding protein complex physical 1 1 1 Affinity Capture-MS
STO1 YMR125W Large subunit of the nuclear mRNA cap-binding protein complex genetic 1 1 1 Negative Genetic
URN1 YPR152C Protein of unknown function containing WW and FF domains physical 1 1 1 Affinity Capture-MS
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
UBC4 YBR082C Ubiquitin-conjugating enzyme (E2) physical 1 1 1 Protein-RNA
RPS0A YGR214W Ribosomal 40S subunit protein S0A physical 1 1 1 Affinity Capture-MS
RPS2 YGL123W Protein component of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPS7A YOR096W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS9A YPL081W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS10A YOR293W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS12 YOR369C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS13 YDR064W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS15 YOL040C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS18A YDR450W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS19A YOL121C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS20 YHL015W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL25 YOL127W Ribosomal 60S subunit protein L25 physical 1 1 1 Affinity Capture-MS
RPL26A YLR344W Ribosomal 60S subunit protein L26A physical 1 1 1 Affinity Capture-MS
RPS27A YKL156W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS3 YNL178W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS3 YNL178W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
TUF1 YOR187W Mitochondrial translation elongation factor Tu (EF-Tu) genetic 1 1 1 Negative Genetic
REB1 YBR049C RNA polymerase I enhancer binding protein genetic 1 1 1 Positive Genetic
RIB7 YBR153W Diaminohydroxyphoshoribosylaminopyrimidine deaminase genetic 1 1 1 Positive Genetic
TRS23 YDR246W Core component of transport protein particle (TRAPP) complexes I-III genetic 1 1 1 Positive Genetic
SPP41 YDR464W Protein of unknown function genetic 1 1 1 Positive Genetic
RET2 YFR051C Delta subunit of the coatomer complex (COPI) genetic 1 1 1 Positive Genetic
RNA15 YGL044C Component of the cleavage and polyadenylation factor I (CF I) genetic 1 1 1 Positive Genetic
RPT6 YGL048C ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Positive Genetic
RPN1 YHR027C Non-ATPase base subunit of the 19S RP of the 26S proteasome genetic 1 1 1 Positive Genetic
STU2 YLR045C Microtubule polymerase of the XMAP215/Dis1 family genetic 1 1 1 Positive Genetic
TAF9 YMR236W Subunit (17 kDa) of TFIID and SAGA complexes genetic 1 1 1 Positive Genetic
SRP1 YNL189W Karyopherin alpha homolog genetic 1 1 1 Positive Genetic
RAP1 YNL216W Essential DNA-binding transcription regulator that binds many loci genetic 1 1 1 Positive Genetic
RPT5 YOR117W ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Positive Genetic
RPT4 YOR259C ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Positive Genetic
VAM7 YGL212W Vacuolar SNARE protein genetic 1 1 1 Positive Genetic
YAT1 YAR035W Outer mitochondrial carnitine acetyltransferase genetic 1 1 1 Positive Genetic
SNF4 YGL115W Activating gamma subunit of the AMP-activated Snf1p kinase complex genetic 1 1 1 Positive Genetic
ZRT1 YGL255W High-affinity zinc transporter of the plasma membrane genetic 1 1 1 Positive Genetic
SCH9 YHR205W AGC family protein kinase genetic 1 1 1 Positive Genetic
SET4 YJL105W Chromatin-associated protein involved in control of stress response genetic 1 1 1 Positive Genetic
TOS7 YOL019W Protein involved in secretion and cell wall organization genetic 1 1 1 Positive Genetic
SGF11 YPL047W Integral subunit of SAGA histone acetyltransferase complex genetic 1 1 1 Positive Genetic
RER2 YBR002C Forms the dehydrodolichyl diphosphate synthase (DDS) complex with NUS1 genetic 1 1 1 Negative Genetic
RPG1 YBR079C eIF3a subunit of the eukaryotic translation initiation factor 3 (eIF3) genetic 1 1 1 Negative Genetic
RIB5 YBR256C Riboflavin synthase genetic 1 1 1 Negative Genetic
RSP5 YER125W NEDD4 family E3 ubiquitin ligase genetic 1 1 1 Negative Genetic
UTP9 YHR196W Nucleolar protein genetic 1 1 1 Negative Genetic
SMC4 YLR086W Subunit of the condensin complex genetic 1 1 1 Negative Genetic
SMC5 YOL034W Subunit of the SMC5-SMC6 complex genetic 1 1 1 Negative Genetic
TBF1 YPL128C Telobox-containing general regulatory factor genetic 1 1 1 Negative Genetic
SUA7 YPR086W Transcription factor TFIIB genetic 1 1 1 Negative Genetic
TAF10 YDR167W Subunit (145 kDa) of TFIID and SAGA complexes genetic 1 1 1 Negative Genetic
TCP1 YDR212W Alpha subunit of chaperonin-containing T-complex genetic 1 1 1 Negative Genetic
SEC26 YDR238C Essential beta-coat protein of the COPI coatomer genetic 1 1 1 Negative Genetic
SNU56 YDR240C Component of U1 snRNP required for mRNA splicing via spliceosome genetic 1 1 1 Negative Genetic
RRP45 YDR280W Exosome non-catalytic core component genetic 1 1 1 Negative Genetic
SRP101 YDR292C Signal recognition particle (SRP) receptor alpha subunit genetic 1 1 1 Negative Genetic
SRB7 YDR308C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
UTP4 YDR324C Subunit of U3-containing 90S preribosome and SSU processome complexes genetic 1 1 1 Negative Genetic
YRA1 YDR381W Nuclear polyadenylated RNA-binding protein genetic 1 1 1 Negative Genetic
TLG1 YDR468C Essential t-SNARE that mediates fusion of vesicles with the late Golgi genetic 1 1 1 Negative Genetic
RBA50 YDR527W Protein involved in transcription genetic 1 1 1 Negative Genetic
WBP1 YEL002C Beta subunit of the oligosaccharyl transferase glycoprotein complex genetic 1 1 1 Negative Genetic
UTP7 YER082C Nucleolar protein genetic 1 1 1 Negative Genetic
TSC11 YER093C Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p) genetic 1 1 1 Negative Genetic
SPT15 YER148W TATA-binding protein (TBP) genetic 1 1 1 Negative Genetic
STT3 YGL022W Catalytic subunit of the oligosaccharyltransferase complex of the ER l genetic 1 1 1 Negative Genetic
SEC27 YGL137W Essential beta'-coat protein of the COPI coatomer genetic 1 1 1 Negative Genetic
SUA5 YGL169W Protein involved in threonylcarbamoyl adenosine biosynthesis genetic 1 1 1 Negative Genetic
THG1 YGR024C tRNAHis guanylyltransferase genetic 1 1 1 Negative Genetic
UFD1 YGR048W Substrate-recruiting cofactor of the Cdc48p-Npl4p-Ufd1p segregase genetic 1 1 1 Negative Genetic
PTI1 YGR156W Essential component of CPF (cleavage and polyadenylation factor) genetic 1 1 1 Negative Genetic
TAF1 YGR274C TFIID subunit, involved in RNA pol II transcription initiation genetic 1 1 1 Negative Genetic
RPB3 YIL021W RNA polymerase II third largest subunit B44 genetic 1 1 1 Negative Genetic
RHO3 YIL118W Non-essential small GTPase of the Rho/Rac family of Ras-like proteins genetic 1 1 1 Negative Genetic
RFA3 YJL173C Subunit of heterotrimeric Replication Protein A (RPA) genetic 1 1 1 Negative Genetic
URB2 YJR041C Protein required for normal metabolism of the rRNA primary transcript genetic 1 1 1 Negative Genetic
SWD2 YKL018W Subunit of the COMPASS (Set1C) histone H3K4 methyltransferase complex genetic 1 1 1 Negative Genetic
SRP102 YKL154W Signal recognition particle (SRP) receptor beta subunit genetic 1 1 1 Negative Genetic
YKT6 YKL196C Vesicle membrane protein (v-SNARE) with acyltransferase activity genetic 1 1 1 Negative Genetic
TOR2 YKL203C PIK-related protein kinase and rapamycin target genetic 1 1 1 Negative Genetic
SOF1 YLL011W Protein required for biogenesis of 40S (small) ribosomal subunit genetic 1 1 1 Negative Genetic
RPL15A YLR029C Ribosomal 60S subunit protein L15A genetic 1 1 1 Negative Genetic
RRN5 YLR141W Protein involved in transcription of rDNA by RNA polymerase I genetic 1 1 1 Negative Genetic
SEC10 YLR166C Essential 100kDa subunit of the exocyst complex genetic 1 1 1 Negative Genetic
UTP13 YLR222C Nucleolar protein genetic 1 1 1 Negative Genetic
YHC1 YLR298C Component of the U1 snRNP complex required for pre-mRNA splicing genetic 1 1 1 Negative Genetic
UTP21 YLR409C Subunit of U3-containing 90S preribosome and SSU processome complexes genetic 1 1 1 Negative Genetic
SEC39 YLR440C Component of the Dsl1p tethering complex genetic 1 1 1 Negative Genetic
TAP42 YMR028W Essential protein involved in the TOR signaling pathway genetic 1 1 1 Negative Genetic
TIF34 YMR146C eIF3i subunit of the eukaryotic translation initiation factor 3 (eIF3) genetic 1 1 1 Negative Genetic
ROT1 YMR200W Molecular chaperone involved in protein folding in ER genetic 1 1 1 Negative Genetic
PSE1 YMR308C Karyopherin/importin that interacts with the nuclear pore complex genetic 1 1 1 Negative Genetic
RPC19 YNL113W RNA polymerase subunit AC19 genetic 1 1 1 Negative Genetic
SSU72 YNL222W Phosphatase and transcription/RNA-processing factor genetic 1 1 1 Negative Genetic
SEC12 YNR026C Guanine nucleotide exchange factor (GEF) genetic 1 1 1 Negative Genetic
RPB11 YOL005C RNA polymerase II subunit B12.5 genetic 1 1 1 Negative Genetic
RPL3 YOR063W Ribosomal 60S subunit protein L3 genetic 1 1 1 Negative Genetic
THI80 YOR143C Thiamine pyrophosphokinase genetic 1 1 1 Negative Genetic
RPB10 YOR210W RNA polymerase subunit ABC10-beta genetic 1 1 1 Negative Genetic
TRE2 YOR256C Transferrin receptor-like protein genetic 1 1 1 Negative Genetic
SOG2 YOR353C Key component of the RAM signaling network genetic 1 1 1 Negative Genetic
PRT1 YOR361C eIF3b subunit of the eukaryotic translation initiation factor 3 (eIF3) genetic 1 1 1 Negative Genetic
TFC8 YPL007C Subunit of RNA polymerase III transcription initiation factor complex genetic 1 1 1 Negative Genetic
TAF3 YPL011C TFIID subunit (47 kDa) genetic 1 1 1 Negative Genetic
SWI1 YPL016W Subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Negative Genetic
ULP1 YPL020C Protease that specifically cleaves Smt3p protein conjugates genetic 1 1 1 Negative Genetic
SEC16 YPL085W COPII vesicle coat protein required for ER transport vesicle budding genetic 1 1 1 Negative Genetic
RAD53 YPL153C DNA damage response kinase genetic 1 1 1 Negative Genetic
TIF6 YPR016C Constituent of 66S pre-ribosomal particles genetic 1 1 1 Negative Genetic
TAH18 YPR048W Conserved NAPDH-dependent diflavin reductase genetic 1 1 1 Negative Genetic
SEC8 YPR055W Essential 121 kDa subunit of the exocyst complex genetic 1 1 1 Negative Genetic
RDS3 YPR094W Component of the SF3b subcomplex of the U2 snRNP genetic 1 1 1 Negative Genetic
YTH1 YPR107C Essential RNA-binding component of cleavage and polyadenylation factor genetic 1 1 1 Negative Genetic
SGV1 YPR161C Cyclin (Bur2p)-dependent protein kinase genetic 1 1 1 Negative Genetic
RHO1 YPR165W GTP-binding protein of the rho subfamily of Ras-like proteins genetic 1 1 1 Negative Genetic
RPS11B YBR048W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
RPS14A YCR031C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
RPS24A YER074W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
YNL140C YNL140C Protein of unknown function genetic 1 1 1 Negative Genetic
RPS30B YOR182C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
RPL21B YPL079W Ribosomal 60S subunit protein L21B genetic 1 1 1 Negative Genetic
SWD1 YAR003W Subunit of the COMPASS (Set1C) complex genetic 1 1 1 Negative Genetic
SLA1 YBL007C Cytoskeletal protein binding protein genetic 1 1 1 Negative Genetic
YBL029C-A YBL029C-A Protein of unknown function genetic 1 1 1 Negative Genetic
PSY4 YBL046W Regulatory subunit of protein phosphatase PP4 genetic 1 1 1 Negative Genetic
SAS3 YBL052C Histone acetyltransferase catalytic subunit of NuA3 complex genetic 1 1 1 Negative Genetic
SFT2 YBL102W Tetra-spanning membrane protein found mostly in the late Golgi genetic 1 1 1 Negative Genetic
YBR071W YBR071W Protein of unknown function found in the cytoplasm and bud neck genetic 1 1 1 Negative Genetic
YBR072C-A YBR072C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
RXT2 YBR095C Component of the histone deacetylase Rpd3L complex genetic 1 1 1 Negative Genetic
TYR1 YBR166C Prephenate dehydrogenase involved in tyrosine biosynthesis genetic 1 1 1 Negative Genetic
SSE2 YBR169C Member of Hsp110 subclass of the heat shock protein 70 (HSP70) family genetic 1 1 1 Negative Genetic
RGD1 YBR260C GTPase-activating protein (RhoGAP) for Rho3p and Rho4p genetic 1 1 1 Negative Genetic
YDL199C YDL199C Putative transporter genetic 1 1 1 Negative Genetic
YDR109C YDR109C D-ribulokinase genetic 1 1 1 Negative Genetic
YDR169C-A YDR169C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
RAD9 YDR217C DNA damage-dependent checkpoint protein genetic 1 1 1 Negative Genetic
RTT103 YDR289C Protein involved in transcription termination by RNA polymerase II genetic 1 1 1 Negative Genetic
SUM1 YDR310C Transcriptional repressor that regulates middle-sporulation genes genetic 1 1 1 Negative Genetic
YFT2 YDR319C Protein needed for ER membrane biosynthesis in response to ER stress genetic 1 1 1 Negative Genetic
SPT3 YDR392W Subunit of the SAGA and SAGA-like transcriptional regulatory complexes genetic 1 1 1 Negative Genetic
SSN2 YDR443C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
YRF1-1 YDR545W Helicase encoded by the Y' element of subtelomeric regions genetic 1 1 1 Negative Genetic
RML2 YEL050C Mitochondrial ribosomal protein of the large subunit (L2) genetic 1 1 1 Negative Genetic
YEL077C YEL077C Helicase-like protein encoded within the telomeric Y' element genetic 1 1 1 Negative Genetic
THO1 YER063W Conserved nuclear RNA-binding protein genetic 1 1 1 Negative Genetic
TRP2 YER090W Anthranilate synthase genetic 1 1 1 Negative Genetic
UBP3 YER151C Ubiquitin-specific protease that cleaves Ub-protein fusions genetic 1 1 1 Negative Genetic
YER186C YER186C Putative protein of unknown function genetic 1 1 1 Negative Genetic
YER189W YER189W Putative protein of unknown function genetic 1 1 1 Negative Genetic
RPL2A YFR031C-A Ribosomal 60S subunit protein L2A genetic 1 1 1 Negative Genetic
ROG1 YGL144C Lipase with specificity for monoacylglycerol genetic 1 1 1 Negative Genetic
SKI8 YGL213C Ski complex component and WD-repeat protein genetic 1 1 1 Negative Genetic
YGR174W-A YGR174W-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
YHL048C-A YHL048C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
SLT2 YHR030C Serine/threonine MAP kinase genetic 1 1 1 Negative Genetic
SFB3 YHR098C Component of the Sec23p-Sfb3p heterodimer of the COPII vesicle coat genetic 1 1 1 Negative Genetic
UBA4 YHR111W E1-like protein that activates Urm1p before urmylation genetic 1 1 1 Negative Genetic
PTH1 YHR189W One of two mitochondrially-localized peptidyl-tRNA hydrolases genetic 1 1 1 Negative Genetic
YHR213W-B YHR213W-B Pseudogenic fragment with similarity to flocculins genetic 1 1 1 Negative Genetic
YIL046W-A YIL046W-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
YIL055C YIL055C Putative protein of unknown function genetic 1 1 1 Negative Genetic
SEC28 YIL076W Epsilon-COP subunit of the coatomer genetic 1 1 1 Negative Genetic
SDS3 YIL084C Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
TPK1 YJL164C cAMP-dependent protein kinase catalytic subunit genetic 1 1 1 Negative Genetic
QCR8 YJL166W Subunit 8 of ubiquinol cytochrome-c reductase (Complex III) genetic 1 1 1 Negative Genetic
SET2 YJL168C Histone methyltransferase with a role in transcriptional elongation genetic 1 1 1 Negative Genetic
YJR079W YJR079W Putative protein of unknown function genetic 1 1 1 Negative Genetic
THI11 YJR156C Protein involved in synthesis of the thiamine precursor HMP genetic 1 1 1 Negative Genetic
SOR1 YJR159W Sorbitol dehydrogenase genetic 1 1 1 Negative Genetic
PSG1 YKL077W Protein that promotes the transport and maturation of Pma1 with Exp1 genetic 1 1 1 Negative Genetic
STE6 YKL209C Plasma membrane ATP-binding cassette (ABC) transporter genetic 1 1 1 Negative Genetic
VPS501 YKR078W Vacuolar SNX-BAR protein genetic 1 1 1 Negative Genetic
RTT109 YLL002W Histone acetyltransferase genetic 1 1 1 Negative Genetic
SSA2 YLL024C HSP70 family ATP-binding protein genetic 1 1 1 Negative Genetic
YLL032C YLL032C Protein of unknown function genetic 1 1 1 Negative Genetic
SDH2 YLL041C Iron-sulfur protein subunit of succinate dehydrogenase genetic 1 1 1 Negative Genetic
YLR159W YLR159W Putative protein of unknown function genetic 1 1 1 Negative Genetic
YPT6 YLR262C Rab family GTPase genetic 1 1 1 Negative Genetic
RSO55 YLR281C Mitochondrial protein of unknown function genetic 1 1 1 Negative Genetic
SEC72 YLR292C Non-essential subunit of Sec63 complex genetic 1 1 1 Negative Genetic
VIP1 YLR410W Bifunctional inositol pyrophosphate kinase and phosphatase genetic 1 1 1 Negative Genetic
URA4 YLR420W Dihydroorotase genetic 1 1 1 Negative Genetic
VPS71 YML041C Nucleosome-binding component of the SWR1 complex genetic 1 1 1 Negative Genetic
RCO1 YMR075W Essential component of the Rpd3S histone deacetylase complex genetic 1 1 1 Negative Genetic
SPT21 YMR179W Protein with a role in transcriptional silencing genetic 1 1 1 Negative Genetic
YMR262W YMR262W Protein of unknown function genetic 1 1 1 Negative Genetic
SAP30 YMR263W Component of Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
YMR315W-A YMR315W-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
YNL042W-B YNL042W-B Putative protein of unknown function genetic 1 1 1 Negative Genetic
SFB2 YNL049C Component of the Sec23p-Sfb2p heterodimer of the COPII vesicle coat genetic 1 1 1 Negative Genetic
VAC7 YNL054W Integral vacuolar membrane protein genetic 1 1 1 Negative Genetic
TOM70 YNL121C Component of the TOM (translocase of outer membrane) complex genetic 1 1 1 Negative Genetic
YNL134C YNL134C NADH-dependent aldehyde reductase genetic 1 1 1 Negative Genetic
SIN4 YNL236W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
ZWF1 YNL241C Glucose-6-phosphate dehydrogenase (G6PD) genetic 1 1 1 Negative Genetic
SLA2 YNL243W Adaptor protein that links actin to clathrin and endocytosis genetic 1 1 1 Negative Genetic
TRF5 YNL299W Non-canonical poly(A) polymerase genetic 1 1 1 Negative Genetic
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes genetic 1 1 1 Negative Genetic
SWM2 YNR004W Protein with a role in snRNA and snoRNA cap trimethylation genetic 1 1 1 Negative Genetic
RCF2 YNR018W Cytochrome c oxidase subunit genetic 1 1 1 Negative Genetic
SIN3 YOL004W Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 1 1 1 Negative Genetic
YOL163W YOL163W Putative protein of unknown function genetic 1 1 1 Negative Genetic
YOL166W-A YOL166W-A Protein of unknown function genetic 1 1 1 Negative Genetic
RRP6 YOR001W Nuclear exosome exonuclease component genetic 1 1 1 Negative Genetic
RBL2 YOR265W Protein involved in microtubule morphogenesis genetic 1 1 1 Negative Genetic
YOR296W YOR296W Putative protein of unknown function genetic 1 1 1 Negative Genetic
YOR389W YOR389W Putative protein of unknown function genetic 1 1 1 Negative Genetic
SSN3 YPL042C Component of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
UME1 YPL139C Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 1 1 1 Negative Genetic
TGS1 YPL157W Trimethyl guanosine synthase, conserved nucleolar methyl transferase genetic 1 1 1 Negative Genetic
YPL277C YPL277C Putative protein of unknown function genetic 1 1 1 Negative Genetic
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 1 1 1 Positive Genetic
PRP11 YDL043C Subunit of the SF3a splicing factor complex genetic 1 1 1 Synthetic Lethality
PRP42 YDR235W U1 snRNP protein involved in splicing genetic 1 1 1 Negative Genetic
MSH4 YFL003C Protein involved in meiotic recombination genetic 1 1 1 Negative Genetic
ACE2 YLR131C Transcription factor required for septum destruction after cytokinesis genetic 1 1 1 Negative Genetic
BCK1 YJL095W MAPKKK acting in the protein kinase C signaling pathway genetic 1 1 1 Negative Genetic
FUN19 YAL034C Non-essential protein of unknown function genetic 1 1 1 Positive Genetic
BRE2 YLR015W Subunit of COMPASS (Set1C) complex genetic 1 1 1 Negative Genetic
FES1 YBR101C Hsp70 (Ssa1p) nucleotide exchange factor genetic 1 1 1 Negative Genetic
CAR2 YLR438W L-ornithine transaminase (OTAse) genetic 1 1 1 Negative Genetic
AKL1 YBR059C Ser/Thr protein kinase genetic 1 1 1 Negative Genetic
HYP2 YEL034W Translation elongation factor eIF-5A genetic 1 1 1 Negative Genetic
DCS1 YLR270W Non-essential hydrolase involved in mRNA decapping genetic 1 1 1 Negative Genetic
PBS2 YJL128C MAP kinase kinase of the HOG signaling pathway genetic 1 1 1 Positive Genetic
GSF2 YML048W Endoplasmic reticulum (ER) localized integral membrane protein genetic 1 1 1 Negative Genetic
HSH49 YOR319W U2-snRNP associated splicing factor genetic 1 1 1 Negative Genetic
KOG1 YHR186C Subunit of TORC1 genetic 1 1 1 Negative Genetic
PMA2 YPL036W Plasma membrane H+-ATPase genetic 1 1 1 Negative Genetic
BOL2 YGL220W Cytosolic protein involved in repression of iron regulon transcription genetic 1 1 1 Negative Genetic
CCT5 YJR064W Subunit of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Negative Genetic
LIA1 YJR070C Deoxyhypusine hydroxylase genetic 1 1 1 Negative Genetic
PBR1 YNL181W Putative oxidoreductase genetic 1 1 1 Negative Genetic
DLD3 YEL071W 2-hydroxyglutarate transhydrogenase, and minor D-lactate dehydrogenase genetic 1 1 1 Negative Genetic
ERG10 YPL028W Acetyl-CoA C-acetyltransferase (acetoacetyl-CoA thiolase) genetic 1 1 1 Negative Genetic
ELM1 YKL048C Serine/threonine protein kinase genetic 1 1 1 Negative Genetic
FAR10 YLR238W Protein involved in recovery from arrest in response to pheromone genetic 1 1 1 Negative Genetic
POL30 YBR088C Proliferating cell nuclear antigen (PCNA) genetic 1 1 1 Negative Genetic
CTF13 YMR094W Subunit of the CBF3 complex genetic 1 1 1 Negative Genetic
PBA1 YLR199C Protein involved in 20S proteasome assembly genetic 1 1 1 Negative Genetic
HIR1 YBL008W Subunit of the HIR complex genetic 1 1 1 Negative Genetic
CDC15 YAR019C Hippo-like kinase of the Mitotic Exit Network genetic 1 1 1 Negative Genetic
MAG2 YLR427W Cytoplasmic protein of unknown function genetic 1 1 1 Negative Genetic
KRI1 YNL308C Essential nucleolar protein required for 40S ribosome biogenesis genetic 1 1 1 Positive Genetic
LAS1 YKR063C Endonuclease involved in pre-rRNA processing at both ends of ITS2 genetic 1 1 1 Negative Genetic
CAC2 YML102W Subunit of chromatin assembly factor I (CAF-1), with Rlf2p and Msi1p genetic 1 1 1 Negative Genetic
CWC21 YDR482C Protein involved in RNA splicing by the spliceosome physical 1 1 1 Affinity Capture-MS
ISU1 YPL135W Conserved protein of the mitochondrial matrix genetic 1 1 1 Negative Genetic
LHS1 YKL073W Molecular chaperone of the endoplasmic reticulum lumen genetic 1 1 1 Negative Genetic
MER1 YNL210W mRNA-binding protein required for meiosis-specific mRNA splicing physical 1 1 1 Two-hybrid
PAC2 YER007W Microtubule effector required for tubulin heterodimer formation genetic 1 1 1 Negative Genetic
AHC1 YOR023C Subunit of the Ada histone acetyltransferase complex physical 1 1 1 Two-hybrid
NOP53 YPL146C Nucleolar protein physical 1 1 1 Two-hybrid
MDH2 YOL126C Cytoplasmic malate dehydrogenase genetic 1 1 1 Negative Genetic
LSM8 YJR022W Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
DBF2 YGR092W Ser/Thr kinase involved in transcription and stress response genetic 1 1 1 Negative Genetic
ISA1 YLL027W Protein required for maturation of mitochondrial [4Fe-4S] proteins genetic 1 1 1 Negative Genetic
PMI40 YER003C Mannose-6-phosphate isomerase genetic 1 1 1 Negative Genetic
EXO70 YJL085W Subunit of the exocyst complex genetic 1 1 1 Negative Genetic
DDI1 YER143W Aspartic-type endopeptidase genetic 1 1 1 Negative Genetic
MCM10 YIL150C Essential chromatin-associated protein genetic 1 1 1 Positive Genetic
IPK1 YDR315C Inositol 1,3,4,5,6-pentakisphosphate 2-kinase genetic 1 1 1 Negative Genetic
CWC24 YLR323C General splicing factor genetic 1 1 1 Negative Genetic
MOB2 YFL034C-B Activator of Cbk1p kinase genetic 1 1 1 Negative Genetic
ASM4 YDL088C FG-nucleoporin component of central core of nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
NUF2 YOL069W Component of the kinetochore-associated Ndc80 complex genetic 1 1 1 Negative Genetic
HSP10 YOR020C Mitochondrial matrix co-chaperonin genetic 1 1 1 Negative Genetic
PRP5 YBR237W RNA helicase in the DEAD-box family genetic 1 1 1 Negative Genetic
PBY1 YBR094W Putative tubulin tyrosine ligase associated with P-bodies genetic 1 1 1 Negative Genetic
ISY1 YJR050W Member of the NineTeen Complex (NTC) genetic 1 1 1 Negative Genetic
GPI16 YHR188C Subunit of the glycosylphosphatidylinositol transamidase complex genetic 1 1 1 Negative Genetic
LAA2 YBL010C Clathrin adaptor (adaptin) accessory protein genetic 1 1 1 Negative Genetic
NST1 YNL091W Translational inhibitor and suppressor of proteasome-assembly defects genetic 1 1 1 Negative Genetic
IBD2 YNL164C Component of the BUB2-dependent spindle checkpoint pathway genetic 1 1 1 Negative Genetic
COG4 YPR105C Essential component of the conserved oligomeric Golgi complex genetic 1 1 1 Negative Genetic
BOS1 YLR078C v-SNARE (vesicle specific SNAP receptor) genetic 1 1 1 Negative Genetic
CDC27 YBL084C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) physical 1 1 1 Two-hybrid
COG5 YNL051W Component of the conserved oligomeric Golgi complex genetic 1 1 1 Negative Genetic
NNF1 YJR112W Essential component of the outer kinetochore MIND complex genetic 1 1 1 Negative Genetic
CHL1 YPL008W Probable DNA helicase genetic 1 1 1 Negative Genetic
CDC21 YOR074C Thymidylate synthase genetic 1 1 1 Negative Genetic
ARP6 YLR085C Actin-related protein that binds nucleosomes genetic 1 1 1 Negative Genetic
PRP2 YNR011C RNA-dependent DExD/H-box ATPase physical 1 1 1 Affinity Capture-MS
CSE4 YKL049C Centromeric histone H3-like protein physical 1 1 1 Two-hybrid
MIF2 YKL089W Centromeric CDEIII region binding protein physical 1 1 1 Two-hybrid
BUR6 YER159C Subunit of a heterodimeric NC2 transcription regulator complex genetic 1 1 1 Negative Genetic
BUB1 YGR188C Protein kinase involved in the cell cycle checkpoint into anaphase genetic 1 1 1 Synthetic Lethality
GEA1 YJR031C Guanine nucleotide exchange factor for ADP ribosylation factors (ARFs) genetic 1 1 1 Negative Genetic
HXK2 YGL253W Hexokinase isoenzyme 2 genetic 1 1 1 Negative Genetic
KAR9 YPL269W Spindle positioning factor genetic 1 1 1 Negative Genetic
PAN1 YIR006C Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p genetic 1 1 1 Negative Genetic
ATG2 YNL242W Peripheral membrane protein required for autophagic vesicle formation genetic 1 1 1 Negative Genetic
MPT5 YGL178W mRNA-binding protein of the PUF family physical 1 1 1 Affinity Capture-RNA
MUD2 YKL074C Protein involved in early pre-mRNA splicing genetic 1 1 1 Negative Genetic
ARG80 YMR042W Transcription factor involved in regulating arginine-responsive genes genetic 1 1 1 Negative Genetic
AFI1 YOR129C Arf3p polarization-specific docking factor genetic 1 1 1 Negative Genetic
GTS1 YGL181W Protein involved in Arf3p regulation and in transcription regulation genetic 1 1 1 Synthetic Lethality
PET494 YNR045W Mitochondrial translational activator specific for the COX3 mRNA genetic 1 1 1 Negative Genetic
PRP16 YKR086W DEAH-box RNA helicase genetic 1 1 1 Negative Genetic
ENT2 YLR206W Epsin-like protein required for endocytosis and actin patch assembly genetic 1 1 1 Negative Genetic
MSL5 YLR116W Component of commitment complex genetic 1 1 1 Negative Genetic
PMT3 YOR321W Protein O-mannosyltransferase genetic 1 1 1 Negative Genetic
BET4 YJL031C Alpha subunit of Type II geranylgeranyltransferase genetic 1 1 1 Negative Genetic
PER33 YLR064W Protein that localizes to the endoplasmic reticulum genetic 1 1 1 Positive Genetic
GAB1 YLR459W Subunit of the glycosylphosphatidylinositol transamidase complex genetic 1 1 1 Negative Genetic
IXR1 YKL032C Transcriptional repressor that regulates hypoxic genes during normoxia genetic 1 1 1 Negative Genetic
PET127 YOR017W Protein with a role in 5'-end processing of mitochondrial RNAs physical 1 1 1 Two-hybrid
DPM1 YPR183W Dolichol phosphate mannose (Dol-P-Man) synthase of ER membrane genetic 1 1 1 Negative Genetic
MDM1 YML104C PtdIns-3-P binding protein that tethers the ER to vacuoles at NVJs physical 1 1 1 Two-hybrid
MRC1 YCL061C S-phase checkpoint protein required for DNA replication physical 1 1 1 Two-hybrid
ARO80 YDR421W Zinc finger transcriptional activator of the Zn2Cys6 family physical 1 1 1 Two-hybrid
AUS1 YOR011W Plasma membrane sterol transporter of the ATP-binding cassette family genetic 1 1 1 Negative Genetic
OKP1 YGR179C Outer kinetochore protein required for accurate chromosome segregation physical 1 1 1 Two-hybrid
PDP3 YLR455W Component of the NuA3b histone acetyltransferase complex genetic 1 1 1 Negative Genetic
GAT2 YMR136W Protein containing GATA family zinc finger motifs genetic 1 1 1 Negative Genetic
GPI2 YPL076W Protein involved in the synthesis of GlcNAc-PI genetic 1 1 1 Negative Genetic
ERI1 YPL096C-A Endoplasmic reticulum membrane protein that binds and inhibits Ras2p genetic 1 1 1 Negative Genetic
GLK1 YCL040W Glucokinase genetic 1 1 1 Negative Genetic
NSI1 YDR026C RNA polymerase I termination factor physical 1 1 1 Two-hybrid
FCF2 YLR051C Nucleolar protein involved in the early steps of 35S rRNA processing genetic 1 1 1 Negative Genetic
AIM22 YJL046W Lipoate-protein ligase genetic 1 1 1 Negative Genetic
JIP4 YDR475C Protein of unknown function genetic 1 1 1 Negative Genetic
ISD11 YER048W-A Cysteine desulfurase (Nfs1p) activator genetic 1 1 1 Negative Genetic
MTG1 YMR097C Putative GTPase peripheral to the mitochondrial inner membrane genetic 1 1 1 Negative Genetic
MET10 YFR030W Subunit alpha of assimilatory sulfite reductase genetic 1 1 1 Negative Genetic
ARA2 YMR041C NAD-dependent arabinose dehydrogenase genetic 1 1 1 Negative Genetic
CAB4 YGR277C Subunit of the CoA-Synthesizing Protein Complex (CoA-SPC) genetic 1 1 1 Negative Genetic
IRC8 YJL051W Bud tip localized protein of unknown function genetic 1 1 1 Negative Genetic
OLE1 YGL055W Delta(9) fatty acid desaturase genetic 1 1 1 Negative Genetic
PMU1 YKL128C Putative phosphomutase genetic 1 1 1 Negative Genetic
APS1 YLR170C Small subunit of the clathrin-associated adaptor complex AP-1 genetic 1 1 1 Negative Genetic
LIP5 YOR196C Protein involved in biosynthesis of the coenzyme lipoic acid genetic 1 1 1 Negative Genetic
PEX32 YBR168W Peroxisomal integral membrane protein genetic 1 1 1 Negative Genetic
MUB1 YMR100W MYND domain-containing protein genetic 1 1 1 Negative Genetic
CSA1 YPR174C Protein of unknown function genetic 1 1 1 Negative Genetic
CHS6 YJL099W Member of the ChAPs (Chs5p-Arf1p-binding proteins) family genetic 1 1 1 Positive Genetic
IGD1 YFR017C Cytoplasmic protein that inhibits Gdb1p glycogen debranching activity genetic 1 1 1 Negative Genetic
IDI1 YPL117C Isopentenyl diphosphate:dimethylallyl diphosphate isomerase genetic 1 1 1 Negative Genetic
BST1 YFL025C GPI inositol deacylase of the endoplasmic reticulum (ER) genetic 1 1 1 Negative Genetic
AIM29 YKR074W Protein of unknown function genetic 1 1 1 Negative Genetic
DEG1 YFL001W tRNA:pseudouridine synthase genetic 1 1 1 Negative Genetic
FPS1 YLL043W Aquaglyceroporin, plasma membrane channel genetic 1 1 1 Negative Genetic
GPI12 YMR281W ER membrane protein involved in the second step of GPI anchor assembly genetic 1 1 1 Negative Genetic
MPD1 YOR288C Member of the protein disulfide isomerase (PDI) family genetic 1 1 1 Negative Genetic
ALG6 YOR002W ER-luminal alpha 1,3 glucosyltransferase genetic 1 1 1 Negative Genetic
GPI19 YDR437W Subunit of GPI-GlcNAc transferase involved in synthesis of GlcNAc-PI genetic 1 1 1 Negative Genetic
ASI1 YMR119W Subunit of the inner nuclear membrane Asi ubiquitin ligase complex genetic 1 1 1 Negative Genetic
NCB2 YDR397C Subunit of a heterodimeric NC2 transcription regulator complex genetic 1 1 1 Negative Genetic
ALG14 YBR070C Component of UDP-GlcNAc transferase genetic 1 1 1 Negative Genetic
ILM1 YJR118C Protein of unknown function genetic 1 1 1 Negative Genetic
CEM1 YER061C Mitochondrial beta-keto-acyl synthase genetic 1 1 1 Negative Genetic
ARO10 YDR380W Phenylpyruvate decarboxylase genetic 1 1 1 Negative Genetic
FAA3 YIL009W Long chain fatty acyl-CoA synthetase genetic 1 1 1 Negative Genetic
ERG3 YLR056W C-5 sterol desaturase genetic 1 1 1 Positive Genetic
GPI14 YJR013W Glycosylphosphatidylinositol-alpha 1,4 mannosyltransferase I genetic 1 1 1 Negative Genetic
NFU1 YKL040C Protein involved in Fe-S cluster transfer to mitochondrial clients genetic 1 1 1 Negative Genetic
ATG41 YPL250C Protein of unknown function genetic 1 1 1 Negative Genetic
COX20 YDR231C Mitochondrial inner membrane protein genetic 1 1 1 Negative Genetic
EFM5 YGR001C S-adenosylmethionine-dependent lysine methyltransferase genetic 1 1 1 Negative Genetic
LIH1 YJR107W Putative lipase genetic 1 1 1 Positive Genetic
MCO10 YOR020W-A Mitochondrial protein of unknown function genetic 1 1 1 Negative Genetic
MIC12 YBR262C Component of the MICOS complex genetic 1 1 1 Negative Genetic
MNT2 YGL257C Mannosyltransferase genetic 1 1 1 Negative Genetic
MSC1 YML128C Protein of unknown function genetic 1 1 1 Negative Genetic
MRM2 YGL136C Mitochondrial 2' O-ribose methyltransferase genetic 1 1 1 Negative Genetic
GLD1 YPR109W Component of Dsc E3 ligase complex in Golgi and endosomes genetic 1 1 1 Negative Genetic
LMO1 YLL007C Homolog of mammalian ELMO (Engulfment and celL MOtility) genetic 1 1 1 Negative Genetic
GPI15 YNL038W Protein involved in the synthesis of GlcNAc-PI genetic 1 1 1 Negative Genetic
HBN1 YCL026C-B Protein of unknown function genetic 1 1 1 Negative Genetic
LIP2 YLR239C Lipoyl ligase genetic 1 1 1 Negative Genetic
DLT1 YMR126C Protein of unknown function genetic 1 1 1 Negative Genetic
CHM7 YJL049W Yeast homolog of human CHMP7, localizes to the endoplasmic reticulum genetic 1 1 1 Negative Genetic
EGO2 YCR075W-A Subunit of the EGO/GSE complex genetic 1 1 1 Negative Genetic
GPI8 YDR331W Catalytic subunit of the ER membrane GPI transamidase complex genetic 1 1 1 Negative Genetic
BCD1 YHR040W Essential protein required for the accumulation of box C/D snoRNA genetic 1 1 1 Negative Genetic
CBT1 YKL208W Protein involved in 5' RNA end processing genetic 1 1 1 Negative Genetic
POF1 YCL047C Nicotinamide mononucleotide-specific adenylyltransferase (NMNAT) genetic 1 1 1 Negative Genetic
OAR1 YKL055C Mitochondrial 3-oxoacyl-[acyl-carrier-protein] reductase genetic 1 1 1 Negative Genetic
NAR1 YNL240C Subunit of the cytosolic iron-sulfur (FeS) protein assembly machinery genetic 1 1 1 Negative Genetic
IRC21 YMR073C Protein of unknown function genetic 1 1 1 Negative Genetic
PDE2 YOR360C High-affinity cyclic AMP phosphodiesterase genetic 1 1 1 Negative Genetic
DML1 YMR211W Essential protein involved in mtDNA inheritance genetic 1 1 1 Negative Genetic
APQ12 YIL040W Nuclear envelope/ER integral membrane protein genetic 1 1 1 Negative Genetic
IRS4 YKR019C EH domain-containing protein genetic 1 1 1 Negative Genetic
AGP3 YFL055W Low-affinity amino acid permease genetic 1 1 1 Negative Genetic
PAU24 YBR301W Cell wall mannoprotein genetic 1 1 1 Negative Genetic
MIN3 YMR182W-A Mitochondrial protein of unknown function genetic 1 1 1 Positive Genetic