Standard name Systematic name Name description Description
SMD3 YLR147C Core Sm protein Sm D3 Core Sm protein Sm D3; part of heteroheptameric complex (with Smb1p, Smd1p, Smd2p, Sme1p, Smx3p, and Smx2p) that is part of the spliceosomal U1, U2, U4, and U5 snRNPs; homolog of human Sm D3
Visualize the interactome of SMD3
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
no data no data no data

GFP localization & abundance

GFP localization GFP abundance
no data no data

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
SMD3 1 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
BRR2 YER172C RNA-dependent ATPase RNA helicase (DEIH box) physical 6 2 6 Affinity Capture-MS, Co-purification, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
CEF1 YMR213W Essential splicing factor physical 4 3 4 Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Co-purification
SMB1 YER029C Core Sm protein Sm B physical 4 2 4 Two-hybrid, Two-hybrid, Affinity Capture-MS, Affinity Capture-MS
PRP8 YHR165C Component of U4/U6-U5 snRNP complex physical 4 1 4 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
NAM8 YHR086W RNA binding protein, component of the U1 snRNP protein physical 4 1 4 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
MUD1 YBR119W U1 snRNP A protein physical 4 3 3 Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Co-crystal Structure
STO1 YMR125W Large subunit of the nuclear mRNA cap-binding protein complex physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
CUS1 YMR240C Protein required for assembly of U2 snRNP into the spliceosome physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
LUC7 YDL087C Essential protein associated with the U1 snRNP complex physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
LEA1 YPL213W Component of U2 snRNP complex physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
SMD1 YGR074W Core Sm protein Sm D1 physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
PRP19 YLL036C Splicing factor associated with the spliceosome physical 2 2 2 Affinity Capture-MS, Co-purification
MUD1 YBR119W U1 snRNP A protein genetic 2 2 2 Synthetic Growth Defect, Synthetic Lethality
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 2 2 2 Affinity Capture-RNA, Affinity Capture-MS
MUD2 YKL074C Protein involved in early pre-mRNA splicing genetic 2 2 2 Synthetic Growth Defect, Synthetic Lethality
CWC2 YDL209C Member of the NineTeen Complex (NTC) physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SMX2 YFL017W-A Core Sm protein Sm G physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SMX3 YPR182W Core Sm protein Sm F physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SNT309 YPR101W Member of the NineTeen Complex (NTC) physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SNU66 YOR308C Component of the U4/U6.U5 snRNP complex physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SNU71 YGR013W Component of U1 snRNP required for mRNA splicing via spliceosome physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SNU56 YDR240C Component of U1 snRNP required for mRNA splicing via spliceosome physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
YHC1 YLR298C Component of the U1 snRNP complex required for pre-mRNA splicing physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
CBC2 YPL178W Small subunit of the heterodimeric cap binding complex with Sto1p physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
PRP40 YKL012W U1 snRNP protein involved in splicing physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
PUB1 YNL016W Poly (A)+ RNA-binding protein physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
LSM8 YJR022W Lsm (Like Sm) protein physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SMX2 YFL017W-A Core Sm protein Sm G genetic 2 2 1 Synthetic Lethality, Synthetic Growth Defect
SMX3 YPR182W Core Sm protein Sm F genetic 2 2 1 Synthetic Growth Defect, Synthetic Lethality
SME1 YOR159C Core Sm protein Sm E genetic 2 2 1 Synthetic Lethality, Synthetic Growth Defect
SMD1 YGR074W Core Sm protein Sm D1 genetic 2 2 1 Synthetic Lethality, Synthetic Growth Defect
SMD2 YLR275W Core Sm protein Sm D2 genetic 2 2 1 Synthetic Growth Defect, Synthetic Lethality
XBP1 YIL101C Transcriptional repressor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
REB1 YBR049C RNA polymerase I enhancer binding protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CLF1 YLR117C Member of the NineTeen Complex (NTC) physical 1 1 1 Affinity Capture-MS
RPL38 YLR325C Ribosomal 60S subunit protein L38 physical 1 1 1 Affinity Capture-MS
PRP43 YGL120C RNA helicase in the DEAH-box family physical 1 1 1 Affinity Capture-MS
SMB1 YER029C Core Sm protein Sm B genetic 1 1 1 Synthetic Lethality
SPP382 YLR424W Essential protein that forms a dimer with Ntr2p physical 1 1 1 Affinity Capture-MS
STO1 YMR125W Large subunit of the nuclear mRNA cap-binding protein complex genetic 1 1 1 Synthetic Lethality
SPA2 YLL021W Component of the polarisome physical 1 1 1 Two-hybrid
STB5 YHR178W Transcription factor physical 1 1 1 Two-hybrid
VBA1 YMR088C Permease of basic amino acids in the vacuolar membrane physical 1 1 1 Two-hybrid
SYF1 YDR416W Member of the NineTeen Complex (NTC) physical 1 1 1 Affinity Capture-MS
YJU2 YKL095W Essential protein required for pre-mRNA splicing physical 1 1 1 Affinity Capture-MS
SNU114 YKL173W GTPase component of U5 snRNP involved in mRNA splicing via spliceosome physical 1 1 1 Affinity Capture-MS
YOR097C YOR097C Putative protein of unknown function physical 1 1 1 Affinity Capture-MS
SME1 YOR159C Core Sm protein Sm E physical 1 1 1 Affinity Capture-MS
SRO9 YCL037C Cytoplasmic RNA-binding protein physical 1 1 1 Affinity Capture-RNA
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
TGS1 YPL157W Trimethyl guanosine synthase, conserved nucleolar methyl transferase genetic 1 1 1 Synthetic Growth Defect
LSM6 YDR378C Lsm (Like Sm) protein physical 1 1 1 Affinity Capture-MS
PRP3 YDR473C Splicing factor physical 1 1 1 Affinity Capture-MS
LRP1 YHR081W Nuclear exosome-associated nucleic acid binding protein genetic 1 1 1 Synthetic Lethality
CBC2 YPL178W Small subunit of the heterodimeric cap binding complex with Sto1p genetic 1 1 1 Synthetic Lethality
PRP39 YML046W U1 snRNP protein involved in splicing physical 1 1 1 Affinity Capture-MS
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
CDC12 YHR107C Component of the septin ring that is required for cytokinesis physical 1 1 1 Two-hybrid
LSM4 YER112W Lsm (Like Sm) protein physical 1 1 1 Affinity Capture-MS
NAM8 YHR086W RNA binding protein, component of the U1 snRNP protein genetic 1 1 1 Synthetic Growth Defect
PRP28 YDR243C Pre-mRNA splicing factor genetic 1 1 1 Synthetic Rescue
PRP31 YGR091W Splicing factor physical 1 1 1 Affinity Capture-MS
LEA1 YPL213W Component of U2 snRNP complex genetic 1 1 1 Synthetic Lethality
PRP6 YBR055C Splicing factor physical 1 1 1 Affinity Capture-MS
RAD16 YBR114W Nucleotide excision repair (NER) protein physical 1 1 1 Two-hybrid
PRP9 YDL030W Subunit of the SF3a splicing factor complex physical 1 1 1 Affinity Capture-MS
RSE1 YML049C Protein involved in pre-mRNA splicing physical 1 1 1 Affinity Capture-MS
SMD2 YLR275W Core Sm protein Sm D2 physical 1 1 1 Affinity Capture-MS
BRR1 YPR057W snRNP protein component of spliceosomal snRNPs genetic 1 1 1 Synthetic Growth Defect
PRP11 YDL043C Subunit of the SF3a splicing factor complex physical 1 1 1 Affinity Capture-MS
SEN1 YLR430W ATP-dependent 5' to 3' RNA/DNA and DNA helicase physical 1 1 1 Two-hybrid
CNA1 YLR433C Calcineurin A physical 1 1 1 Two-hybrid
EST1 YLR233C TLC1 RNA-associated factor involved in telomere length regulation physical 1 1 1 Affinity Capture-MS
CWC21 YDR482C Protein involved in RNA splicing by the spliceosome physical 1 1 1 Affinity Capture-MS
ERG11 YHR007C Lanosterol 14-alpha-demethylase genetic 1 1 1 Synthetic Growth Defect
MPT5 YGL178W mRNA-binding protein of the PUF family physical 1 1 1 Affinity Capture-RNA
PRP22 YER013W DEAH-box RNA-dependent ATPase/ATP-dependent RNA helicase physical 1 1 1 Reconstituted Complex
MSL5 YLR116W Component of commitment complex physical 1 1 1 Affinity Capture-MS
MTD1 YKR080W NAD-dependent 5,10-methylenetetrahydrafolate dehydrogenase physical 1 1 1 Two-hybrid
REV7 YIL139C Accessory subunit of DNA polymerase zeta physical 1 1 1 Two-hybrid
ARG56 YER069W Acetylglutamate kinase and N-acetyl-gamma-glutamyl-phosphate reductase physical 1 1 1 Affinity Capture-MS