Standard name Systematic name Name description Description
CEF1 YMR213W Essential splicing factor Essential splicing factor; associated with Prp19p and the spliceosome, contains an N-terminal c-Myb DNA binding motif necessary for cell viability but not for Prp19p association, evolutionarily conserved and homologous to S. pombe Cdc5p
Visualize the interactome of CEF1
Links to external databases:
SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Mito 0.295 0.086 0.167
Nucleus 0.813 0.820 0.944
Cytoplasm NaN 0.051 0.056
Vac/Vac Memb NaN 0.125 NaN

GFP localization & abundance

GFP localization GFP abundance
cytoplasm, nucleus 784

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
CEF1 2 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
PRP19 YLL036C Splicing factor associated with the spliceosome physical 20 6 17 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Far Western, Two-hybrid, Two-hybrid, Co-purification, Co-purification, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Co-purification
SYF1 YDR416W Member of the NineTeen Complex (NTC) physical 12 6 11 Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, Affinity Capture-Western, Affinity Capture-MS, Co-localization, Affinity Capture-Western, Reconstituted Complex, Co-purification
CLF1 YLR117C Member of the NineTeen Complex (NTC) physical 11 5 8 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, Two-hybrid, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Co-purification
CWC2 YDL209C Member of the NineTeen Complex (NTC) physical 7 3 6 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Co-purification
PRP46 YPL151C Member of the NineTeen Complex (NTC) physical 7 3 6 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Co-purification
SNT309 YPR101W Member of the NineTeen Complex (NTC) physical 7 3 6 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Co-purification
SNU114 YKL173W GTPase component of U5 snRNP involved in mRNA splicing via spliceosome physical 6 4 6 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-RNA, Reconstituted Complex, Co-purification
CWC22 YGR278W Spliceosome-associated protein that is required for pre-mRNA splicing physical 6 3 5 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Co-purification
PRP8 YHR165C Component of U4/U6-U5 snRNP complex physical 6 3 5 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Co-purification
PRP22 YER013W DEAH-box RNA-dependent ATPase/ATP-dependent RNA helicase physical 6 2 5 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Reconstituted Complex
CDC40 YDR364C Pre-mRNA splicing factor physical 5 3 5 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Co-purification
ECM2 YBR065C Pre-mRNA splicing factor physical 5 3 5 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Co-purification
PRP45 YAL032C Protein required for pre-mRNA splicing physical 5 3 5 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Co-purification
SMD2 YLR275W Core Sm protein Sm D2 physical 5 3 5 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Co-purification
LEA1 YPL213W Component of U2 snRNP complex physical 5 3 5 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Co-purification
BUD31 YCR063W Component of the SF3b subcomplex of the U2 snRNP physical 5 3 5 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Co-purification
YJU2 YKL095W Essential protein required for pre-mRNA splicing physical 4 4 4 Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Co-purification
SYF2 YGR129W Member of the NineTeen Complex (NTC) physical 4 4 4 Affinity Capture-MS, Two-hybrid, Reconstituted Complex, Co-purification
CWC21 YDR482C Protein involved in RNA splicing by the spliceosome physical 4 3 4 Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Co-purification
SMB1 YER029C Core Sm protein Sm B physical 4 3 4 Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Co-purification
SMD3 YLR147C Core Sm protein Sm D3 physical 4 3 4 Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Co-purification
ISY1 YJR050W Member of the NineTeen Complex (NTC) physical 4 4 3 Affinity Capture-MS, Reconstituted Complex, Two-hybrid, Co-purification
BRR2 YER172C RNA-dependent ATPase RNA helicase (DEIH box) physical 4 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
CWC15 YDR163W Non-essential protein involved in pre-mRNA splicing physical 3 3 3 Affinity Capture-MS, Reconstituted Complex, Co-purification
MSL1 YIR009W U2B component of U2 snRNP physical 3 3 3 Affinity Capture-MS, Reconstituted Complex, Co-purification
SMD1 YGR074W Core Sm protein Sm D1 physical 3 3 3 Affinity Capture-MS, Reconstituted Complex, Co-purification
SMX2 YFL017W-A Core Sm protein Sm G physical 3 3 3 Affinity Capture-MS, Reconstituted Complex, Co-purification
SMX3 YPR182W Core Sm protein Sm F physical 3 3 3 Affinity Capture-MS, Reconstituted Complex, Co-purification
SME1 YOR159C Core Sm protein Sm E physical 3 3 3 Affinity Capture-MS, Reconstituted Complex, Co-purification
HSH155 YMR288W U2-snRNP associated splicing factor physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RSE1 YML049C Protein involved in pre-mRNA splicing physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
CWC23 YGL128C Component of a complex containing Cef1p physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
PRP22 YER013W DEAH-box RNA-dependent ATPase/ATP-dependent RNA helicase genetic 3 3 2 Dosage Rescue, Synthetic Growth Defect, Negative Genetic
CWC21 YDR482C Protein involved in RNA splicing by the spliceosome genetic 3 2 2 Synthetic Lethality, Negative Genetic, Negative Genetic
BUB1 YGR188C Protein kinase involved in the cell cycle checkpoint into anaphase genetic 3 2 2 Synthetic Lethality, Negative Genetic, Negative Genetic
CDC40 YDR364C Pre-mRNA splicing factor genetic 2 2 2 Synthetic Rescue, Negative Genetic
SPP382 YLR424W Essential protein that forms a dimer with Ntr2p physical 2 2 2 Affinity Capture-MS, Affinity Capture-Western
PRP45 YAL032C Protein required for pre-mRNA splicing genetic 2 2 2 Synthetic Lethality, Negative Genetic
SLU7 YDR088C RNA splicing factor physical 2 2 2 Affinity Capture-MS, Reconstituted Complex
LRP1 YHR081W Nuclear exosome-associated nucleic acid binding protein genetic 2 2 2 Negative Genetic, Positive Genetic
MAD1 YGL086W Coiled-coil protein involved in spindle-assembly checkpoint genetic 2 2 2 Synthetic Lethality, Negative Genetic
PRP2 YNR011C RNA-dependent DExD/H-box ATPase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
PRP43 YGL120C RNA helicase in the DEAH-box family physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
LEA1 YPL213W Component of U2 snRNP complex genetic 2 1 2 Negative Genetic, Negative Genetic
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
YKE2 YLR200W Subunit of the heterohexameric Gim/prefoldin protein complex genetic 2 1 2 Negative Genetic, Negative Genetic
CBC2 YPL178W Small subunit of the heterodimeric cap binding complex with Sto1p physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
PRP8 YHR165C Component of U4/U6-U5 snRNP complex genetic 2 2 1 Synthetic Rescue, Synthetic Growth Defect
TUB1 YML085C Alpha-tubulin genetic 2 2 1 Synthetic Rescue, Dosage Rescue
CLF1 YLR117C Member of the NineTeen Complex (NTC) genetic 2 1 1 Negative Genetic, Negative Genetic
PRP43 YGL120C RNA helicase in the DEAH-box family genetic 2 1 1 Negative Genetic, Negative Genetic
RSE1 YML049C Protein involved in pre-mRNA splicing genetic 2 1 1 Negative Genetic, Negative Genetic
SNU114 YKL173W GTPase component of U5 snRNP involved in mRNA splicing via spliceosome genetic 2 1 1 Negative Genetic, Negative Genetic
CWC22 YGR278W Spliceosome-associated protein that is required for pre-mRNA splicing genetic 2 1 1 Negative Genetic, Negative Genetic
CWC15 YDR163W Non-essential protein involved in pre-mRNA splicing genetic 2 1 1 Negative Genetic, Negative Genetic
IST3 YIR005W Component of the U2 snRNP genetic 2 1 1 Negative Genetic, Negative Genetic
NTC20 YBR188C Member of the NineTeen Complex (NTC) genetic 2 1 1 Negative Genetic, Negative Genetic
ISY1 YJR050W Member of the NineTeen Complex (NTC) genetic 2 1 1 Negative Genetic, Negative Genetic
SLU7 YDR088C RNA splicing factor genetic 2 1 1 Negative Genetic, Negative Genetic
SYF2 YGR129W Member of the NineTeen Complex (NTC) genetic 2 1 1 Negative Genetic, Negative Genetic
PRP16 YKR086W DEAH-box RNA helicase genetic 2 1 1 Negative Genetic, Negative Genetic
URN1 YPR152C Protein of unknown function containing WW and FF domains genetic 2 1 1 Negative Genetic, Negative Genetic
PRP18 YGR006W Splicing factor and component of snRNP U5 genetic 2 1 1 Negative Genetic, Negative Genetic
RBA50 YDR527W Protein involved in transcription genetic 2 1 1 Positive Genetic, Positive Genetic
SEC63 YOR254C Essential subunit of Sec63 complex genetic 2 1 1 Positive Genetic, Positive Genetic
GPN2 YOR262W Putative GTPase with a specific role in RNA pol II and polIII biogenes genetic 2 1 1 Positive Genetic, Positive Genetic
STU1 YBL034C Microtubule plus-end-tracking non-motor protein genetic 2 1 1 Negative Genetic, Negative Genetic
SEC17 YBL050W Alpha-SNAP cochaperone genetic 2 1 1 Negative Genetic, Negative Genetic
SUP35 YDR172W Translation termination factor eRF3 genetic 2 1 1 Negative Genetic, Negative Genetic
SPC105 YGL093W Subunit of a kinetochore-microtubule binding complex genetic 2 1 1 Negative Genetic, Negative Genetic
COF1 YLL050C Cofilin, involved in pH-dependent actin filament depolarization genetic 2 1 1 Negative Genetic, Negative Genetic
SEC22 YLR268W R-SNARE protein genetic 2 1 1 Negative Genetic, Negative Genetic
TAD3 YLR316C Subunit of tRNA-specific adenosine-34 deaminase genetic 2 1 1 Negative Genetic, Negative Genetic
RDS3 YPR094W Component of the SF3b subcomplex of the U2 snRNP genetic 2 1 1 Negative Genetic, Negative Genetic
SWC3 YAL011W Protein of unknown function genetic 2 1 1 Negative Genetic, Negative Genetic
NUM1 YDR150W Protein required for nuclear migration genetic 2 1 1 Negative Genetic, Negative Genetic
SWR1 YDR334W Swi2/Snf2-related ATPase genetic 2 1 1 Negative Genetic, Negative Genetic
VPS72 YDR485C Htz1p-binding component of the SWR1 complex genetic 2 1 1 Negative Genetic, Negative Genetic
PAC11 YDR488C Dynein intermediate chain, microtubule motor protein genetic 2 1 1 Negative Genetic, Negative Genetic
DRN1 YGR093W Splicing factor that modulates turnover of branched RNAs by Dbr1p genetic 2 1 1 Negative Genetic, Negative Genetic
LDB18 YLL049W Component of the dynactin complex genetic 2 1 1 Negative Genetic, Negative Genetic
PML1 YLR016C Subunit of the RES complex genetic 2 1 1 Negative Genetic, Negative Genetic
RBL2 YOR265W Protein involved in microtubule morphogenesis genetic 2 1 1 Negative Genetic, Negative Genetic
NIP100 YPL174C Large subunit of the dynactin complex genetic 2 1 1 Negative Genetic, Negative Genetic
CIN2 YPL241C GTPase-activating protein (GAP) for Cin4p genetic 2 1 1 Negative Genetic, Negative Genetic
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 2 1 1 Negative Genetic, Negative Genetic
AAR2 YBL074C Component of the U5 snRNP complex genetic 2 1 1 Negative Genetic, Negative Genetic
BUD13 YGL174W Subunit of the RES complex genetic 2 1 1 Negative Genetic, Negative Genetic
ARP1 YHR129C Actin-related protein of the dynactin complex genetic 2 1 1 Negative Genetic, Negative Genetic
BOS1 YLR078C v-SNARE (vesicle specific SNAP receptor) genetic 2 1 1 Negative Genetic, Negative Genetic
SPT10 YJL127C Histone H3 acetylase with a role in transcriptional regulation regulation 1 1 1 DNA to cDNA expression microarray evidence
CDC73 YLR418C Component of the Paf1p complex genetic 1 1 1 Synthetic Lethality
PRP46 YPL151C Member of the NineTeen Complex (NTC) genetic 1 1 1 Negative Genetic
SMD2 YLR275W Core Sm protein Sm D2 genetic 1 1 1 Negative Genetic
SNT309 YPR101W Member of the NineTeen Complex (NTC) genetic 1 1 1 Negative Genetic
YJU2 YKL095W Essential protein required for pre-mRNA splicing genetic 1 1 1 Negative Genetic
CWC25 YNL245C Splicing factor required for the first step of pre-mRNA splicing physical 1 1 1 Affinity Capture-MS
CWC25 YNL245C Splicing factor required for the first step of pre-mRNA splicing genetic 1 1 1 Negative Genetic
CWC27 YPL064C Component of a complex containing Cef1p physical 1 1 1 Affinity Capture-MS
IST3 YIR005W Component of the U2 snRNP physical 1 1 1 Affinity Capture-MS
NTC20 YBR188C Member of the NineTeen Complex (NTC) physical 1 1 1 Affinity Capture-MS
PRP11 YDL043C Subunit of the SF3a splicing factor complex physical 1 1 1 Affinity Capture-MS
PRP21 YJL203W Subunit of the SF3a splicing factor complex physical 1 1 1 Affinity Capture-MS
PRP9 YDL030W Subunit of the SF3a splicing factor complex physical 1 1 1 Affinity Capture-MS
SMX3 YPR182W Core Sm protein Sm F genetic 1 1 1 Negative Genetic
CEF1 YMR213W Essential splicing factor physical 1 1 1 Two-hybrid
GFA1 YKL104C Glutamine-fructose-6-phosphate amidotransferase physical 1 1 1 Affinity Capture-MS
CUS1 YMR240C Protein required for assembly of U2 snRNP into the spliceosome physical 1 1 1 Affinity Capture-MS
PAB1 YER165W Poly(A) binding protein physical 1 1 1 Affinity Capture-MS
NTR2 YKR022C Essential protein that forms a dimer with Ntr1p physical 1 1 1 Affinity Capture-Western
SPC25 YER018C Component of the kinetochore-associated Ndc80 complex physical 1 1 1 Two-hybrid
CWC24 YLR323C General splicing factor physical 1 1 1 Affinity Capture-Western
CWC24 YLR323C General splicing factor genetic 1 1 1 Negative Genetic
PRP16 YKR086W DEAH-box RNA helicase physical 1 1 1 Affinity Capture-MS
URN1 YPR152C Protein of unknown function containing WW and FF domains physical 1 1 1 Affinity Capture-MS
SNU66 YOR308C Component of the U4/U6.U5 snRNP complex physical 1 1 1 Affinity Capture-MS
RPS17A YML024W Ribosomal protein 51 (rp51) of the small (40s) subunit physical 1 1 1 Affinity Capture-RNA
PRP18 YGR006W Splicing factor and component of snRNP U5 physical 1 1 1 Reconstituted Complex
PUB1 YNL016W Poly (A)+ RNA-binding protein physical 1 1 1 Affinity Capture-MS
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-MS
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein genetic 1 1 1 Negative Genetic
UBI4 YLL039C Ubiquitin genetic 1 1 1 Negative Genetic
SLS1 YLR139C Mitochondrial membrane protein genetic 1 1 1 Negative Genetic
MSM1 YGR171C Mitochondrial methionyl-tRNA synthetase (MetRS) genetic 1 1 1 Negative Genetic
CSE2 YNR010W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
RNY1 YPL123C Vacuolar RNase of the T(2) family genetic 1 1 1 Positive Genetic
SMC3 YJL074C Subunit of the multiprotein cohesin complex genetic 1 1 1 Synthetic Lethality
MRE11 YMR224C Nuclease subunit of the MRX complex with Rad50p and Xrs2p genetic 1 1 1 Synthetic Lethality
TTI1 YKL033W Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Negative Genetic
RPN5 YDL147W Subunit of the CSN and 26S proteasome lid complexes genetic 1 1 1 Positive Genetic
RPB7 YDR404C RNA polymerase II subunit B16 genetic 1 1 1 Positive Genetic
SKI6 YGR195W Exosome non-catalytic core component genetic 1 1 1 Positive Genetic
RRP4 YHR069C Exosome non-catalytic core component genetic 1 1 1 Positive Genetic
CIA2 YHR122W Component of cytosolic iron-sulfur protein assembly (CIA) machinery genetic 1 1 1 Positive Genetic
STS1 YIR011C Protein required for localizing proteasomes to the nucleus genetic 1 1 1 Positive Genetic
NOP56 YLR197W Essential evolutionarily-conserved nucleolar protein genetic 1 1 1 Positive Genetic
SEN1 YLR430W ATP-dependent 5' to 3' RNA/DNA and DNA helicase genetic 1 1 1 Positive Genetic
SGT1 YOR057W Cochaperone protein genetic 1 1 1 Positive Genetic
RPB2 YOR151C RNA polymerase II second largest subunit B150 genetic 1 1 1 Positive Genetic
CSL4 YNL232W Exosome non-catalytic core component genetic 1 1 1 Positive Genetic
RPB10 YOR210W RNA polymerase subunit ABC10-beta genetic 1 1 1 Positive Genetic
DEP1 YAL013W Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Positive Genetic
NUP170 YBL079W Subunit of inner ring of nuclear pore complex (NPC) genetic 1 1 1 Positive Genetic
ETR1 YBR026C 2-enoyl thioester reductase genetic 1 1 1 Positive Genetic
RXT2 YBR095C Component of the histone deacetylase Rpd3L complex genetic 1 1 1 Positive Genetic
STE50 YCL032W Adaptor protein for various signaling pathways genetic 1 1 1 Positive Genetic
SNT1 YCR033W Set3C histone deacetylase scaffold genetic 1 1 1 Positive Genetic
CSM1 YCR086W Nucleolar protein that mediates homolog segregation during meiosis I genetic 1 1 1 Positive Genetic
OST4 YDL232W Subunit of the oligosaccharyltransferase complex of the ER lumen genetic 1 1 1 Positive Genetic
IPT1 YDR072C Inositolphosphotransferase genetic 1 1 1 Positive Genetic
RRP8 YDR083W Nucleolar S-adenosylmethionine-dependent rRNA methyltransferase genetic 1 1 1 Positive Genetic
XRN1 YGL173C Evolutionarily-conserved 5'-3' exonuclease genetic 1 1 1 Positive Genetic
SDS3 YIL084C Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Positive Genetic
MRT4 YKL009W Protein involved in mRNA turnover and ribosome assembly genetic 1 1 1 Positive Genetic
TPO5 YKL174C Protein involved in excretion of putrescine and spermidine genetic 1 1 1 Positive Genetic
RPS21A YKR057W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
LIP2 YLR239C Lipoyl ligase genetic 1 1 1 Positive Genetic
RPS28B YLR264W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
CHS5 YLR330W Component of the exomer complex genetic 1 1 1 Positive Genetic
SIN3 YOL004W Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 1 1 1 Positive Genetic
RRP6 YOR001W Nuclear exosome exonuclease component genetic 1 1 1 Positive Genetic
ELG1 YOR144C Subunit of an alternative replication factor C complex genetic 1 1 1 Positive Genetic
LIP5 YOR196C Protein involved in biosynthesis of the coenzyme lipoic acid genetic 1 1 1 Positive Genetic
CUP9 YPL177C Homeodomain-containing transcriptional repressor genetic 1 1 1 Positive Genetic
VMA3 YEL027W Proteolipid subunit c of the V0 domain of vacuolar H(+)-ATPase genetic 1 1 1 Positive Genetic
DEG1 YFL001W tRNA:pseudouridine synthase genetic 1 1 1 Positive Genetic
SLA2 YNL243W Adaptor protein that links actin to clathrin and endocytosis genetic 1 1 1 Positive Genetic
REB1 YBR049C RNA polymerase I enhancer binding protein genetic 1 1 1 Negative Genetic
TSR1 YDL060W Protein required for processing of 20S pre-rRNA in the cytoplasm genetic 1 1 1 Negative Genetic
RPC11 YDR045C RNA polymerase III subunit C11 genetic 1 1 1 Negative Genetic
NCB2 YDR397C Subunit of a heterodimeric NC2 transcription regulator complex genetic 1 1 1 Negative Genetic
POL5 YEL055C Protein involved in 60S assembly and pre-40S AFs recycling genetic 1 1 1 Negative Genetic
PMI40 YER003C Mannose-6-phosphate isomerase genetic 1 1 1 Negative Genetic
VHT1 YGR065C High-affinity plasma membrane H+-biotin (vitamin H) symporter genetic 1 1 1 Negative Genetic
PRP40 YKL012W U1 snRNP protein involved in splicing genetic 1 1 1 Negative Genetic
STU2 YLR045C Microtubule polymerase of the XMAP215/Dis1 family genetic 1 1 1 Negative Genetic
MSL5 YLR116W Component of commitment complex genetic 1 1 1 Negative Genetic
HSP60 YLR259C Tetradecameric mitochondrial chaperonin genetic 1 1 1 Negative Genetic
LSM3 YLR438C-A Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
SEC18 YBR080C AAA ATPase and SNARE disassembly chaperone genetic 1 1 1 Negative Genetic
SLI15 YBR156C Subunit of the conserved chromosomal passenger complex (CPC) genetic 1 1 1 Negative Genetic
TRS20 YBR254C Core component of transport protein particle (TRAPP) complexes I-III genetic 1 1 1 Negative Genetic
MPS1 YDL028C Dual-specificity kinase genetic 1 1 1 Negative Genetic
GPI19 YDR437W Subunit of GPI-GlcNAc transferase involved in synthesis of GlcNAc-PI genetic 1 1 1 Negative Genetic
RSP5 YER125W NEDD4 family E3 ubiquitin ligase genetic 1 1 1 Negative Genetic
COG3 YER157W Essential component of the conserved oligomeric Golgi complex genetic 1 1 1 Negative Genetic
MOB2 YFL034C-B Activator of Cbk1p kinase genetic 1 1 1 Negative Genetic
SEC27 YGL137W Essential beta'-coat protein of the COPI coatomer genetic 1 1 1 Negative Genetic
DAM1 YGR113W Essential subunit of the Dam1 complex (aka DASH complex) genetic 1 1 1 Negative Genetic
MET30 YIL046W F-box protein containing five copies of the WD40 motif genetic 1 1 1 Negative Genetic
RPC17 YJL011C RNA polymerase III subunit C17 genetic 1 1 1 Negative Genetic
KRE9 YJL174W Glycoprotein involved in cell wall beta-glucan assembly genetic 1 1 1 Negative Genetic
SED5 YLR026C cis-Golgi t-SNARE syntaxin genetic 1 1 1 Negative Genetic
RPP0 YLR340W Conserved ribosomal protein P0 of the ribosomal stalk genetic 1 1 1 Negative Genetic
RSC9 YML127W Component of the RSC chromatin remodeling complex genetic 1 1 1 Negative Genetic
GPI15 YNL038W Protein involved in the synthesis of GlcNAc-PI genetic 1 1 1 Negative Genetic
SEC12 YNR026C Guanine nucleotide exchange factor (GEF) genetic 1 1 1 Negative Genetic
NOG2 YNR053C Putative GTPase genetic 1 1 1 Negative Genetic
RPO31 YOR116C RNA polymerase III largest subunit C160 genetic 1 1 1 Negative Genetic
PFY1 YOR122C Profilin genetic 1 1 1 Negative Genetic
GPI2 YPL076W Protein involved in the synthesis of GlcNAc-PI genetic 1 1 1 Negative Genetic
MOT1 YPL082C Essential protein involved in regulation of transcription genetic 1 1 1 Negative Genetic
IPL1 YPL209C Aurora kinase of chromosomal passenger complex genetic 1 1 1 Negative Genetic
THI80 YOR143C Thiamine pyrophosphokinase genetic 1 1 1 Negative Genetic
HSH49 YOR319W U2-snRNP associated splicing factor genetic 1 1 1 Negative Genetic
TIF6 YPR016C Constituent of 66S pre-ribosomal particles genetic 1 1 1 Negative Genetic
SPN1 YPR133C Protein involved in RNA polymerase II transcription genetic 1 1 1 Negative Genetic
MDM10 YAL010C Subunit of both the ERMES and the SAM complex genetic 1 1 1 Negative Genetic
LTE1 YAL024C Protein similar to GDP/GTP exchange factors genetic 1 1 1 Negative Genetic
YAL065C YAL065C Putative protein of unknown function genetic 1 1 1 Negative Genetic
YAR029W YAR029W Member of DUP240 gene family but contains no transmembrane domains genetic 1 1 1 Negative Genetic
SLA1 YBL007C Cytoskeletal protein binding protein genetic 1 1 1 Negative Genetic
PIN4 YBL051C Protein involved in G2/M phase progression and response to DNA damage genetic 1 1 1 Negative Genetic
NTH2 YBR001C Putative neutral trehalase, required for thermotolerance genetic 1 1 1 Negative Genetic
CSG2 YBR036C Endoplasmic reticulum membrane protein genetic 1 1 1 Negative Genetic
PTC4 YBR125C Cytoplasmic type 2C protein phosphatase (PP2C) genetic 1 1 1 Negative Genetic
SHE3 YBR130C Protein adaptor between Myo4p and the She2p-mRNA complex genetic 1 1 1 Negative Genetic
CSH1 YBR161W Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit genetic 1 1 1 Negative Genetic
COS111 YBR203W Protein required for antifungal drug ciclopirox olamine resistance genetic 1 1 1 Negative Genetic
SWC5 YBR231C Component of the SWR1 complex genetic 1 1 1 Negative Genetic
NHP10 YDL002C Non-essential INO80 chromatin remodeling complex subunit genetic 1 1 1 Negative Genetic
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p genetic 1 1 1 Negative Genetic
MDH3 YDL078C Peroxisomal malate dehydrogenase genetic 1 1 1 Negative Genetic
SAC3 YDR159W mRNA export factor genetic 1 1 1 Negative Genetic
RTT103 YDR289C Protein involved in transcription termination by RNA polymerase II genetic 1 1 1 Negative Genetic
YDR415C YDR415C Putative aminopeptidase genetic 1 1 1 Negative Genetic
DYN2 YDR424C Cytoplasmic light chain dynein, microtubule motor protein genetic 1 1 1 Negative Genetic
RPL27B YDR471W Ribosomal 60S subunit protein L27B genetic 1 1 1 Negative Genetic
URC2 YDR520C Putative Zn(II)2Cys6 motif containing transcription factor genetic 1 1 1 Negative Genetic
PAD1 YDR538W Phenylacrylic acid decarboxylase genetic 1 1 1 Negative Genetic
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p) genetic 1 1 1 Negative Genetic
IES1 YFL013C Subunit of the INO80 chromatin remodeling complex genetic 1 1 1 Negative Genetic
FAB1 YFR019W 1-phosphatidylinositol-3-phosphate 5-kinase genetic 1 1 1 Negative Genetic
RPL2A YFR031C-A Ribosomal 60S subunit protein L2A genetic 1 1 1 Negative Genetic
NUT1 YGL151W Component of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
KEX1 YGL203C Cell death protease essential for hypochlorite-induced apoptosis genetic 1 1 1 Negative Genetic
KIP3 YGL216W Kinesin-related antiparallel sliding motor protein genetic 1 1 1 Negative Genetic
TAD1 YGL243W tRNA-specific adenosine deaminase genetic 1 1 1 Negative Genetic
ORM1 YGR038W Protein that mediates sphingolipid homeostasis genetic 1 1 1 Negative Genetic
PAC10 YGR078C Part of the heteromeric co-chaperone GimC/prefoldin complex genetic 1 1 1 Negative Genetic
VMA21 YGR105W Integral membrane protein required for V-ATPase function genetic 1 1 1 Negative Genetic
MAL12 YGR292W Maltase (alpha-D-glucosidase) genetic 1 1 1 Negative Genetic
OPI1 YHL020C Transcriptional regulator of a variety of genes genetic 1 1 1 Negative Genetic
SNF6 YHL025W Subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Negative Genetic
NAM8 YHR086W RNA binding protein, component of the U1 snRNP protein genetic 1 1 1 Negative Genetic
STB5 YHR178W Transcription factor genetic 1 1 1 Negative Genetic
FYV10 YIL097W Subunit of GID complex genetic 1 1 1 Negative Genetic
MLP2 YIL149C Myosin-like protein associated with the nuclear envelope genetic 1 1 1 Negative Genetic
DAL81 YIR023W Positive regulator of genes in multiple nitrogen degradation pathways genetic 1 1 1 Negative Genetic
MAD3 YJL013C Subunit of spindle-assembly checkpoint complex genetic 1 1 1 Negative Genetic
SAP185 YJL098W Protein that forms a complex with the Sit4p protein phosphatase genetic 1 1 1 Negative Genetic
KCH1 YJR054W Potassium transporter that mediates K+ influx genetic 1 1 1 Negative Genetic
DCW1 YKL046C Putative mannosidase genetic 1 1 1 Negative Genetic
ELM1 YKL048C Serine/threonine protein kinase genetic 1 1 1 Negative Genetic
LHS1 YKL073W Molecular chaperone of the endoplasmic reticulum lumen genetic 1 1 1 Negative Genetic
SAC1 YKL212W Phosphatidylinositol phosphate phosphatase genetic 1 1 1 Negative Genetic
YSR3 YKR053C Dihydrosphingosine 1-phosphate phosphatase genetic 1 1 1 Negative Genetic
DYN1 YKR054C Cytoplasmic heavy chain dynein genetic 1 1 1 Negative Genetic
MLP1 YKR095W Myosin-like protein associated with the nuclear envelope genetic 1 1 1 Negative Genetic
ENT4 YLL038C Protein of unknown function genetic 1 1 1 Negative Genetic
SND2 YLR065C Protein involved in SRP-independent targeting of substrates to the ER genetic 1 1 1 Negative Genetic
SIC1 YLR079W Cyclin-dependent kinase inhibitor (CKI) genetic 1 1 1 Negative Genetic
NDL1 YLR254C Homolog of nuclear distribution factor NudE genetic 1 1 1 Negative Genetic
VRP1 YLR337C Verprolin, proline-rich actin-associated protein genetic 1 1 1 Negative Genetic
FKS1 YLR342W Catalytic subunit of 1,3-beta-D-glucan synthase genetic 1 1 1 Negative Genetic
ORM2 YLR350W Protein that mediates sphingolipid homeostasis genetic 1 1 1 Negative Genetic
SEI1 YLR404W Seipin involved in lipid droplet (LD) assembly genetic 1 1 1 Negative Genetic
VPS71 YML041C Nucleosome-binding component of the SWR1 complex genetic 1 1 1 Negative Genetic
TUB3 YML124C Alpha-tubulin genetic 1 1 1 Negative Genetic
HDA1 YNL021W Catalytic subunit of class II HDA1 histone deacetylase complex genetic 1 1 1 Negative Genetic
COG6 YNL041C Component of the conserved oligomeric Golgi complex genetic 1 1 1 Negative Genetic
NCS2 YNL119W Protein required for uridine thiolation of Lys(UUU) and Glu(UUC) tRNAs genetic 1 1 1 Negative Genetic
YNL140C YNL140C Protein of unknown function genetic 1 1 1 Negative Genetic
HUB1 YNR032C-A Ubiquitin-like protein modifier genetic 1 1 1 Negative Genetic
PHO80 YOL001W Cyclin genetic 1 1 1 Negative Genetic
TLG2 YOL018C Syntaxin-like t-SNARE genetic 1 1 1 Negative Genetic
MET22 YOL064C Bisphosphate-3'-nucleotidase genetic 1 1 1 Negative Genetic
INO4 YOL108C Transcription factor involved in phospholipid synthesis genetic 1 1 1 Negative Genetic
VPS68 YOL129W Vacuolar membrane protein of unknown function genetic 1 1 1 Negative Genetic
CRC1 YOR100C Mitochondrial inner membrane carnitine transporter genetic 1 1 1 Negative Genetic
RUD3 YOR216C Golgi matrix protein genetic 1 1 1 Negative Genetic
DSE3 YOR264W Daughter cell-specific protein, may help establish daughter fate genetic 1 1 1 Negative Genetic
PNT1 YOR266W Mitochondrial integral inner membrane protein genetic 1 1 1 Negative Genetic
PAC1 YOR269W Regulator of dynein, involved in intracellular transport genetic 1 1 1 Negative Genetic
SNC2 YOR327C Vesicle membrane receptor protein (v-SNARE) genetic 1 1 1 Negative Genetic
PRM4 YPL156C Pheromone-regulated protein proposed to be involved in mating genetic 1 1 1 Negative Genetic
MRN1 YPL184C RNA-binding protein that may be involved in translational regulation genetic 1 1 1 Negative Genetic
MCM16 YPR046W Component of the Ctf19 complex and the COMA subcomplex genetic 1 1 1 Negative Genetic
FUN19 YAL034C Non-essential protein of unknown function genetic 1 1 1 Negative Genetic
HIR1 YBL008W Subunit of the HIR complex genetic 1 1 1 Negative Genetic
IMG2 YCR071C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
COS7 YDL248W Endosomal protein involved in turnover of plasma membrane proteins genetic 1 1 1 Negative Genetic
SSD1 YDR293C Translational repressor genetic 1 1 1 Negative Genetic
TOM1 YDR457W E3 ubiquitin ligase of the hect-domain class genetic 1 1 1 Negative Genetic
GIM4 YEL003W Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Negative Genetic
PAC2 YER007W Microtubule effector required for tubulin heterodimer formation genetic 1 1 1 Negative Genetic
ISC1 YER019W Inositol phosphosphingolipid phospholipase C genetic 1 1 1 Negative Genetic
RPL23B YER117W Ribosomal 60S subunit protein L23B genetic 1 1 1 Negative Genetic
YTA7 YGR270W Chromatin-binding ATPase that regulates histone gene expression genetic 1 1 1 Negative Genetic
MGA2 YIR033W ER membrane protein involved in regulation of OLE1 transcription genetic 1 1 1 Negative Genetic
HAP4 YKL109W Transcription factor genetic 1 1 1 Negative Genetic
MFT1 YML062C Subunit of the THO complex genetic 1 1 1 Negative Genetic
SLM2 YNL047C Phosphoinositide PI4,5P(2) binding protein, forms a complex with Slm1p genetic 1 1 1 Negative Genetic
VAC7 YNL054W Integral vacuolar membrane protein genetic 1 1 1 Negative Genetic
GIM3 YNL153C Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Negative Genetic
SIN4 YNL236W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
MAN2 YNR073C Mannitol dehydrogenase genetic 1 1 1 Negative Genetic
MDH2 YOL126C Cytoplasmic malate dehydrogenase genetic 1 1 1 Negative Genetic
ERI1 YPL096C-A Endoplasmic reticulum membrane protein that binds and inhibits Ras2p genetic 1 1 1 Negative Genetic
THP3 YPR045C Protein that may have a role in transcription elongation genetic 1 1 1 Negative Genetic
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 1 1 1 Negative Genetic
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 1 1 1 Negative Genetic
BMH1 YER177W 14-3-3 protein, major isoform genetic 1 1 1 Negative Genetic
ARP7 YPR034W Component of both the SWI/SNF and RSC chromatin remodeling complexes genetic 1 1 1 Negative Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
CDC11 YJR076C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Negative Genetic
BUD31 YCR063W Component of the SF3b subcomplex of the U2 snRNP genetic 1 1 1 Positive Genetic
BUD21 YOR078W Component of small ribosomal subunit (SSU) processosome genetic 1 1 1 Positive Genetic
BRO1 YPL084W Cytoplasmic class E vacuolar protein sorting (VPS) factor genetic 1 1 1 Negative Genetic
BRE2 YLR015W Subunit of COMPASS (Set1C) complex genetic 1 1 1 Positive Genetic
CAF20 YOR276W Phosphoprotein of the mRNA cap-binding complex physical 1 1 1 Affinity Capture-RNA
ATG17 YLR423C Scaffold protein responsible for phagophore assembly site organization physical 1 1 1 Two-hybrid
BUD13 YGL174W Subunit of the RES complex physical 1 1 1 Affinity Capture-MS
AYR1 YIL124W Bifunctional triacylglycerol lipase and 1-acyl DHAP reductase genetic 1 1 1 Negative Genetic
AHC1 YOR023C Subunit of the Ada histone acetyltransferase complex genetic 1 1 1 Negative Genetic
BUB3 YOR026W Kinetochore checkpoint WD40 repeat protein genetic 1 1 1 Negative Genetic
AIM4 YBR194W Protein proposed to be associated with the nuclear pore complex physical 1 1 1 Affinity Capture-MS
APC5 YOR249C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Positive Genetic
ARP6 YLR085C Actin-related protein that binds nucleosomes genetic 1 1 1 Negative Genetic
BIK1 YCL029C Microtubule-associated protein genetic 1 1 1 Negative Genetic
BET1 YIL004C Type II membrane protein required for vesicular transport genetic 1 1 1 Negative Genetic
BET4 YJL031C Alpha subunit of Type II geranylgeranyltransferase genetic 1 1 1 Negative Genetic
BTS1 YPL069C Geranylgeranyl diphosphate synthase (GGPPS) genetic 1 1 1 Negative Genetic
ASE1 YOR058C Mitotic spindle midzone-localized microtubule bundling protein genetic 1 1 1 Negative Genetic
BRR6 YGL247W Essential nuclear envelope integral membrane protein genetic 1 1 1 Positive Genetic