SLI15 |
YBR156C |
Subunit of the conserved chromosomal passenger complex (CPC) |
physical |
19 |
5 |
14 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Biochemical Activity, Affinity Capture-MS, Two-hybrid, Two-hybrid, Affinity Capture-Western, Two-hybrid, Affinity Capture-Western, Two-hybrid, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Biochemical Activity, Biochemical Activity, Affinity Capture-MS |
BIR1 |
YJR089W |
Subunit of chromosomal passenger complex (CPC) |
physical |
9 |
4 |
7 |
Affinity Capture-MS, Affinity Capture-Western, Two-hybrid, Two-hybrid, Two-hybrid, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-fractionation |
SLI15 |
YBR156C |
Subunit of the conserved chromosomal passenger complex (CPC) |
genetic |
9 |
6 |
6 |
Dosage Rescue, Synthetic Lethality, Dosage Rescue, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Dosage Growth Defect, Phenotypic Enhancement |
DAM1 |
YGR113W |
Essential subunit of the Dam1 complex (aka DASH complex) |
genetic |
9 |
5 |
5 |
Synthetic Lethality, Synthetic Lethality, Synthetic Rescue, Phenotypic Suppression, Synthetic Rescue, Phenotypic Suppression, Positive Genetic, Negative Genetic, Negative Genetic |
DAM1 |
YGR113W |
Essential subunit of the Dam1 complex (aka DASH complex) |
physical |
8 |
2 |
7 |
Affinity Capture-Western, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity |
BIM1 |
YER016W |
Microtubule plus end-tracking protein |
physical |
8 |
4 |
5 |
Two-hybrid, Two-hybrid, Biochemical Activity, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Two-hybrid, Affinity Capture-MS |
SDS22 |
YKL193C |
Regulatory subunit of the type 1 protein phosphatase (PP1) Glc7p |
genetic |
7 |
2 |
7 |
Synthetic Rescue, Dosage Rescue, Dosage Rescue, Synthetic Rescue, Synthetic Rescue, Dosage Rescue, Synthetic Rescue |
GLC7 |
YER133W |
Type 1 S/T protein phosphatase (PP1) catalytic subunit |
genetic |
7 |
3 |
6 |
Dosage Lethality, Synthetic Rescue, Synthetic Rescue, Synthetic Rescue, Synthetic Rescue, Synthetic Rescue, Phenotypic Suppression |
CIN8 |
YEL061C |
Bipolar kinesin motor protein |
genetic |
5 |
4 |
4 |
Synthetic Lethality, Synthetic Growth Defect, Phenotypic Enhancement, Synthetic Lethality, Negative Genetic |
YPI1 |
YFR003C |
Regulatory subunit of the type I protein phosphatase (PP1) Glc7p |
genetic |
5 |
2 |
4 |
Dosage Rescue, Synthetic Rescue, Synthetic Rescue, Synthetic Rescue, Synthetic Rescue |
HHF2 |
YNL030W |
Histone H4 |
genetic |
5 |
4 |
2 |
Synthetic Lethality, Synthetic Growth Defect, Phenotypic Enhancement, Phenotypic Suppression, Synthetic Growth Defect |
CBF2 |
YGR140W |
Essential kinetochore protein |
physical |
4 |
2 |
4 |
Biochemical Activity, Affinity Capture-MS, Affinity Capture-MS, Biochemical Activity |
SET1 |
YHR119W |
Histone methyltransferase, subunit of the COMPASS (Set1C) complex |
genetic |
4 |
1 |
4 |
Synthetic Rescue, Synthetic Rescue, Synthetic Rescue, Synthetic Rescue |
MAD1 |
YGL086W |
Coiled-coil protein involved in spindle-assembly checkpoint |
genetic |
4 |
3 |
3 |
Synthetic Growth Defect, Synthetic Growth Defect, Phenotypic Enhancement, Phenotypic Suppression |
SHP1 |
YBL058W |
UBX domain-containing substrate adaptor for Cdc48p |
genetic |
4 |
3 |
3 |
Dosage Rescue, Synthetic Rescue, Synthetic Rescue, Phenotypic Suppression |
GLC8 |
YMR311C |
Regulatory subunit of protein phosphatase 1 (Glc7p) |
genetic |
4 |
2 |
3 |
Dosage Rescue, Synthetic Rescue, Dosage Rescue, Synthetic Rescue |
BUB3 |
YOR026W |
Kinetochore checkpoint WD40 repeat protein |
genetic |
4 |
2 |
3 |
Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic |
MPS1 |
YDL028C |
Dual-specificity kinase |
genetic |
4 |
3 |
2 |
Phenotypic Suppression, Positive Genetic, Negative Genetic, Negative Genetic |
TCO89 |
YPL180W |
Subunit of TORC1 (Tor1p or Tor2p-Kog1p-Lst8p-Tco89p) |
genetic |
4 |
2 |
2 |
Synthetic Rescue, Synthetic Rescue, Phenotypic Suppression, Synthetic Rescue |
BIM1 |
YER016W |
Microtubule plus end-tracking protein |
genetic |
3 |
2 |
3 |
Synthetic Lethality, Synthetic Lethality, Negative Genetic |
HHT1 |
YBR010W |
Histone H3 |
physical |
3 |
1 |
3 |
Biochemical Activity, Biochemical Activity, Biochemical Activity |
NBL1 |
YHR199C-A |
Subunit of the conserved chromosomal passenger complex (CPC) |
physical |
3 |
3 |
2 |
Affinity Capture-Western, Two-hybrid, Affinity Capture-MS |
TUB2 |
YFL037W |
Beta-tubulin |
genetic |
3 |
3 |
2 |
Negative Genetic, Phenotypic Suppression, Synthetic Growth Defect |
PSE1 |
YMR308C |
Karyopherin/importin that interacts with the nuclear pore complex |
physical |
3 |
2 |
2 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western |
MCM21 |
YDR318W |
Component of the kinetochore sub-complex COMA |
genetic |
3 |
2 |
2 |
Synthetic Lethality, Negative Genetic, Negative Genetic |
MCM22 |
YJR135C |
Outer kinetochore protein and component of the Ctf3 subcomplex |
genetic |
3 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic, Negative Genetic |
BUB1 |
YGR188C |
Protein kinase involved in the cell cycle checkpoint into anaphase |
genetic |
3 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic, Negative Genetic |
CTF8 |
YHR191C |
Subunit of a complex with Ctf18p |
genetic |
3 |
2 |
2 |
Synthetic Lethality, Negative Genetic, Negative Genetic |
CIN1 |
YOR349W |
Tubulin folding factor D involved in beta-tubulin (Tub2p) folding |
genetic |
3 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic, Negative Genetic |
DCC1 |
YCL016C |
Subunit of a complex with Ctf8p and Ctf18p |
genetic |
3 |
2 |
2 |
Synthetic Lethality, Negative Genetic, Negative Genetic |
HHT2 |
YNL031C |
Histone H3 |
genetic |
3 |
3 |
1 |
Synthetic Lethality, Synthetic Growth Defect, Phenotypic Enhancement |
FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
2 |
2 |
2 |
chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments |
DSN1 |
YIR010W |
Essential component of the outer kinetochore MIND complex |
physical |
2 |
2 |
2 |
Biochemical Activity, Affinity Capture-MS |
CDC14 |
YFR028C |
Protein phosphatase required for mitotic exit |
physical |
2 |
2 |
2 |
Co-localization, Affinity Capture-MS |
GAS1 |
YMR307W |
Beta-1,3-glucanosyltransferase required for cell wall assembly |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Positive Genetic |
CIK1 |
YMR198W |
Kinesin-associated protein |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Phenotypic Suppression |
DUO1 |
YGL061C |
Essential subunit of the Dam1 complex (aka DASH complex) |
genetic |
2 |
2 |
2 |
Synthetic Rescue, Positive Genetic |
RRP5 |
YMR229C |
RNA binding protein involved in synthesis of 18S and 5.8S rRNAs |
physical |
2 |
2 |
2 |
Biochemical Activity, Reconstituted Complex |
NDC80 |
YIL144W |
Component of the kinetochore-associated Ndc80 complex |
genetic |
2 |
2 |
2 |
Synthetic Rescue, Phenotypic Enhancement |
IPL1 |
YPL209C |
Aurora kinase of chromosomal passenger complex |
physical |
2 |
2 |
2 |
Biochemical Activity, Affinity Capture-MS |
UTP7 |
YER082C |
Nucleolar protein |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Negative Genetic |
MCM16 |
YPR046W |
Component of the Ctf19 complex and the COMA subcomplex |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Negative Genetic |
YKE2 |
YLR200W |
Subunit of the heterohexameric Gim/prefoldin protein complex |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Negative Genetic |
PAC2 |
YER007W |
Microtubule effector required for tubulin heterodimer formation |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Negative Genetic |
SWC3 |
YAL011W |
Protein of unknown function |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
RTF1 |
YGL244W |
Subunit of RNAPII-associated chromatin remodeling Paf1 complex |
genetic |
2 |
2 |
2 |
Synthetic Rescue, Negative Genetic |
YME1 |
YPR024W |
Catalytic subunit of i-AAA protease complex |
genetic |
2 |
2 |
2 |
Positive Genetic, Negative Genetic |
STU2 |
YLR045C |
Microtubule polymerase of the XMAP215/Dis1 family |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
PHO23 |
YNL097C |
Component of the Rpd3L histone deacetylase complex |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Rescue |
GIM4 |
YEL003W |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
FRK1 |
YPL141C |
Protein kinase of unknown cellular role |
genetic |
2 |
2 |
2 |
Positive Genetic, Dosage Growth Defect |
CDC28 |
YBR160W |
Cyclin-dependent kinase (CDK) catalytic subunit |
physical |
2 |
1 |
2 |
Biochemical Activity, Biochemical Activity |
ASK1 |
YKL052C |
Essential subunit of the Dam1 complex (aka DASH complex) |
physical |
2 |
1 |
2 |
Biochemical Activity, Biochemical Activity |
NDC80 |
YIL144W |
Component of the kinetochore-associated Ndc80 complex |
physical |
2 |
1 |
2 |
Biochemical Activity, Biochemical Activity |
SPC34 |
YKR037C |
Essential subunit of the Dam1 complex (aka DASH complex) |
physical |
2 |
1 |
2 |
Biochemical Activity, Biochemical Activity |
GIP4 |
YAL031C |
Cytoplasmic protein that regulates protein phosphatase 1 Glc7p |
genetic |
2 |
1 |
2 |
Dosage Rescue, Dosage Rescue |
NDC80 |
YIL144W |
Component of the kinetochore-associated Ndc80 complex |
regulation |
2 |
2 |
1 |
protein kinase assay evidence, qualitative western immunoblotting evidence |
ARP8 |
YOR141C |
Nuclear actin-related protein involved in chromatin remodeling |
physical |
2 |
2 |
1 |
Reconstituted Complex, Affinity Capture-Western |
FIN1 |
YDR130C |
Spindle pole body-related intermediate filament protein |
genetic |
2 |
2 |
1 |
Synthetic Growth Defect, Synthetic Rescue |
UBA1 |
YKL210W |
Ubiquitin activating enzyme (E1) |
genetic |
2 |
2 |
1 |
Synthetic Rescue, Phenotypic Suppression |
RCK2 |
YLR248W |
Protein kinase involved in response to oxidative and osmotic stress |
physical |
2 |
2 |
1 |
Reconstituted Complex, Affinity Capture-Western |
TIF11 |
YMR260C |
Translation initiation factor eIF1A |
physical |
2 |
2 |
1 |
Reconstituted Complex, Affinity Capture-Western |
YKL091C |
YKL091C |
Putative phosphatidylinositol/phosphatidylcholine transfer protein |
physical |
2 |
2 |
1 |
Reconstituted Complex, Affinity Capture-Western |
RAS2 |
YNL098C |
GTP-binding protein |
genetic |
2 |
2 |
1 |
Synthetic Rescue, Synthetic Growth Defect |
YTH1 |
YPR107C |
Essential RNA-binding component of cleavage and polyadenylation factor |
genetic |
2 |
2 |
1 |
Positive Genetic, Negative Genetic |
RPL34A |
YER056C-A |
Ribosomal 60S subunit protein L34A |
genetic |
2 |
2 |
1 |
Positive Genetic, Negative Genetic |
RPS0A |
YGR214W |
Ribosomal 40S subunit protein S0A |
genetic |
2 |
2 |
1 |
Positive Genetic, Negative Genetic |
SGS1 |
YMR190C |
RecQ family nucleolar DNA helicase |
genetic |
2 |
2 |
1 |
Positive Genetic, Negative Genetic |
HRQ1 |
YDR291W |
3'-5' DNA helicase of the conserved RecQ family |
genetic |
2 |
2 |
1 |
Positive Genetic, Negative Genetic |
BMH1 |
YER177W |
14-3-3 protein, major isoform |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
CTF18 |
YMR078C |
Subunit of a complex with Ctf8p |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
IML3 |
YBR107C |
Outer kinetochore protein and component of the Ctf19 complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
HSC82 |
YMR186W |
Cytoplasmic chaperone of the Hsp90 family |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
GIM3 |
YNL153C |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
DBF2 |
YGR092W |
Ser/Thr kinase involved in transcription and stress response |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
BAS1 |
YKR099W |
Myb-related transcription factor |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
OKP1 |
YGR179C |
Outer kinetochore protein required for accurate chromosome segregation |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
STU1 |
YBL034C |
Microtubule plus-end-tracking non-motor protein |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
SCC4 |
YER147C |
Subunit of cohesin loading factor (Scc2p-Scc4p) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
SMC1 |
YFL008W |
Subunit of the multiprotein cohesin complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
UTP9 |
YHR196W |
Nucleolar protein |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
SMC3 |
YJL074C |
Subunit of the multiprotein cohesin complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
UTP13 |
YLR222C |
Nucleolar protein |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
UTP15 |
YMR093W |
Nucleolar protein |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
RPA190 |
YOR341W |
RNA polymerase I largest subunit A190 |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
PAT1 |
YCR077C |
Deadenylation-dependent mRNA-decapping factor |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
PAC10 |
YGR078C |
Part of the heteromeric co-chaperone GimC/prefoldin complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
VHS2 |
YIL135C |
Regulator of septin dynamics |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
RPS21A |
YKR057W |
Protein component of the small (40S) ribosomal subunit |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
RPS28B |
YLR264W |
Protein component of the small (40S) ribosomal subunit |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
RTS1 |
YOR014W |
B-type regulatory subunit of protein phosphatase 2A (PP2A) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
HCM1 |
YCR065W |
Forkhead transcription factor |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
SFP1 |
YLR403W |
Regulates transcription of ribosomal protein and biogenesis genes |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
IXR1 |
YKL032C |
Transcriptional repressor that regulates hypoxic genes during normoxia |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
YAP6 |
YDR259C |
Basic leucine zipper (bZIP) transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
CDC28 |
YBR160W |
Cyclin-dependent kinase (CDK) catalytic subunit |
regulation |
1 |
1 |
1 |
quantitative mass spectrometry evidence |
SPT3 |
YDR392W |
Subunit of the SAGA and SAGA-like transcriptional regulatory complexes |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
UGA3 |
YDL170W |
Transcriptional activator for GABA-dependent induction of GABA genes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
CDC13 |
YDL220C |
Single stranded DNA-binding protein found at TG1-3 telomere G-tails |
regulation |
1 |
1 |
1 |
protein kinase assay evidence |
CTR9 |
YOL145C |
Component of the Paf1p complex involved in transcription elongation |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
CEF1 |
YMR213W |
Essential splicing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
CWC25 |
YNL245C |
Splicing factor required for the first step of pre-mRNA splicing |
genetic |
1 |
1 |
1 |
Negative Genetic |
AME1 |
YBR211C |
Essential kinetochore protein associated with microtubules and SPBs |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
AME1 |
YBR211C |
Essential kinetochore protein associated with microtubules and SPBs |
genetic |
1 |
1 |
1 |
Negative Genetic |
CHL4 |
YDR254W |
Outer kinetochore protein required for chromosome stability |
genetic |
1 |
1 |
1 |
Negative Genetic |
CTF19 |
YPL018W |
Outer kinetochore protein, needed for accurate chromosome segregation |
genetic |
1 |
1 |
1 |
Negative Genetic |
CTF3 |
YLR381W |
Outer kinetochore protein that forms a complex with Mcm16p and Mcm22p |
genetic |
1 |
1 |
1 |
Negative Genetic |
CBF5 |
YLR175W |
Pseudouridine synthase catalytic subunit of box H/ACA snoRNPs |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CKA1 |
YIL035C |
Alpha catalytic subunit of casein kinase 2 (CK2) |
genetic |
1 |
1 |
1 |
Negative Genetic |
ESA1 |
YOR244W |
Catalytic subunit of the histone acetyltransferase complex (NuA4) |
genetic |
1 |
1 |
1 |
Negative Genetic |
EAF5 |
YEL018W |
Non-essential subunit of the NuA4 acetyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
DRS1 |
YLL008W |
Nucleolar DEAD-box protein required for ribosome assembly and function |
physical |
1 |
1 |
1 |
Reconstituted Complex |
HAS1 |
YMR290C |
ATP-dependent RNA helicase |
physical |
1 |
1 |
1 |
Biochemical Activity |
HAS1 |
YMR290C |
ATP-dependent RNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
BRR2 |
YER172C |
RNA-dependent ATPase RNA helicase (DEIH box) |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARC1 |
YGL105W |
Protein that binds tRNA and methionyl- and glutamyl-tRNA synthetases |
physical |
1 |
1 |
1 |
Biochemical Activity |
IML1 |
YJR138W |
GTPase-activating protein (GAP) subunit of the Iml1p/SEACIT complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC48 |
YDL126C |
AAA ATPase with protein-unfoldase activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
CSL4 |
YNL232W |
Exosome non-catalytic core component |
genetic |
1 |
1 |
1 |
Negative Genetic |
HCR1 |
YLR192C |
eIF3j component of translation initiation factor 3 (eIF3) |
physical |
1 |
1 |
1 |
Biochemical Activity |
AAR2 |
YBL074C |
Component of the U5 snRNP complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ALA1 |
YOR335C |
Cytoplasmic and mitochondrial alanyl-tRNA synthetase |
physical |
1 |
1 |
1 |
Biochemical Activity |
BCP1 |
YDR361C |
Essential nuclear chaperone for ribosomal protein Rpl23p |
genetic |
1 |
1 |
1 |
Negative Genetic |
CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
APC1 |
YNL172W |
Largest subunit of the Anaphase-Promoting Complex/Cyclosome |
physical |
1 |
1 |
1 |
Two-hybrid |
BUD14 |
YAR014C |
Protein involved in bud-site selection |
genetic |
1 |
1 |
1 |
Dosage Rescue |
HDA1 |
YNL021W |
Catalytic subunit of class II HDA1 histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
BUD31 |
YCR063W |
Component of the SF3b subcomplex of the U2 snRNP |
genetic |
1 |
1 |
1 |
Negative Genetic |
CEG1 |
YGL130W |
Guanylyltransferase involved in mRNA 5' capping |
genetic |
1 |
1 |
1 |
Negative Genetic |
CNS1 |
YBR155W |
TPR-containing co-chaperone |
physical |
1 |
1 |
1 |
Biochemical Activity |
CTK1 |
YKL139W |
Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) |
genetic |
1 |
1 |
1 |
Negative Genetic |
DCP1 |
YOL149W |
Subunit of the Dcp1p-Dcp2p decapping enzyme complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
DCP2 |
YNL118C |
Catalytic subunit of Dcp1p-Dcp2p decapping enzyme complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CIA2 |
YHR122W |
Component of cytosolic iron-sulfur protein assembly (CIA) machinery |
genetic |
1 |
1 |
1 |
Negative Genetic |
EMG1 |
YLR186W |
Methyltransferase for rRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
ENP1 |
YBR247C |
Protein associated with U3 and U14 snoRNAs |
genetic |
1 |
1 |
1 |
Negative Genetic |
FIP1 |
YJR093C |
Subunit of cleavage polyadenylation factor (CPF) |
genetic |
1 |
1 |
1 |
Negative Genetic |
DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
ATG3 |
YNR007C |
E2-like enzyme |
genetic |
1 |
1 |
1 |
Positive Genetic |
IES5 |
YER092W |
Non-essential INO80 chromatin remodeling complex subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
INO4 |
YOL108C |
Transcription factor involved in phospholipid synthesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
BUD21 |
YOR078W |
Component of small ribosomal subunit (SSU) processosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC6 |
YJL194W |
Essential ATP-binding protein required for DNA replication |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
CCT8 |
YJL008C |
Subunit of the cytosolic chaperonin Cct ring complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CCT6 |
YDR188W |
Subunit of the cytosolic chaperonin Cct ring complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
BCY1 |
YIL033C |
Regulatory subunit of the cyclic AMP-dependent protein kinase (PKA) |
genetic |
1 |
1 |
1 |
Dosage Rescue |
BRE2 |
YLR015W |
Subunit of COMPASS (Set1C) complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
CMS1 |
YLR003C |
Putative subunit of the 90S preribosome processome complex |
physical |
1 |
1 |
1 |
Biochemical Activity |
FAR11 |
YNL127W |
Protein involved in recovery from cell cycle arrest |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC13 |
YDL220C |
Single stranded DNA-binding protein found at TG1-3 telomere G-tails |
physical |
1 |
1 |
1 |
Biochemical Activity |
FPR3 |
YML074C |
Nucleolar peptidyl-prolyl cis-trans isomerase (PPIase) |
physical |
1 |
1 |
1 |
Biochemical Activity |
FPR3 |
YML074C |
Nucleolar peptidyl-prolyl cis-trans isomerase (PPIase) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
AKL1 |
YBR059C |
Ser/Thr protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
FIN1 |
YDR130C |
Spindle pole body-related intermediate filament protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
HYP2 |
YEL034W |
Translation elongation factor eIF-5A |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC5 |
YMR001C |
Polo-like kinase required for mitotic exit |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
IDH1 |
YNL037C |
Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase |
genetic |
1 |
1 |
1 |
Positive Genetic |
HTB1 |
YDR224C |
Histone H2B |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
DPS1 |
YLL018C |
Aspartyl-tRNA synthetase, primarily cytoplasmic |
physical |
1 |
1 |
1 |
Biochemical Activity |
BUD13 |
YGL174W |
Subunit of the RES complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
BFA1 |
YJR053W |
Subunit of a two-component GTPase-activating protein, Bfa1p-Bub2p |
physical |
1 |
1 |
1 |
Two-hybrid |
ADK1 |
YDR226W |
Adenylate kinase, required for purine metabolism |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC20 |
YGL116W |
Activator of anaphase-promoting complex/cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Positive Genetic |
GUF1 |
YLR289W |
Mitochondrial matrix GTPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
FHL1 |
YPR104C |
Regulator of ribosomal protein (RP) transcription |
genetic |
1 |
1 |
1 |
Negative Genetic |
HSL7 |
YBR133C |
Protein arginine N-methyltransferase |
physical |
1 |
1 |
1 |
Two-hybrid |
CDC4 |
YFL009W |
F-box protein required for both the G1/S and G2/M phase transitions |
genetic |
1 |
1 |
1 |
Positive Genetic |
CTF13 |
YMR094W |
Subunit of the CBF3 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
AIM46 |
YHR199C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC15 |
YAR019C |
Hippo-like kinase of the Mitotic Exit Network |
physical |
1 |
1 |
1 |
Co-localization |
DIA2 |
YOR080W |
Origin-binding F-box protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
CTF4 |
YPR135W |
Chromatin-associated protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
CLB2 |
YPR119W |
B-type cyclin involved in cell cycle progression |
physical |
1 |
1 |
1 |
Biochemical Activity |
FAL1 |
YDR021W |
Nucleolar protein required for maturation of 18S rRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
FCF1 |
YDR339C |
PINc domain endonuclease |
genetic |
1 |
1 |
1 |
Negative Genetic |
DUO1 |
YGL061C |
Essential subunit of the Dam1 complex (aka DASH complex) |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
FZF1 |
YGL254W |
Transcription factor involved in sulfite metabolism |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC34 |
YDR054C |
Ubiquitin-conjugating enzyme (E2) |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
FIS1 |
YIL065C |
Protein involved in mitochondrial fission and peroxisome abundance |
genetic |
1 |
1 |
1 |
Negative Genetic |
GPN2 |
YOR262W |
Putative GTPase with a specific role in RNA pol II and polIII biogenes |
genetic |
1 |
1 |
1 |
Negative Genetic |
ASK1 |
YKL052C |
Essential subunit of the Dam1 complex (aka DASH complex) |
genetic |
1 |
1 |
1 |
Positive Genetic |
APC11 |
YDL008W |
Catalytic core subunit, Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
CEP3 |
YMR168C |
Essential kinetochore protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
GIP3 |
YPL137C |
Cytoplasmic protein that regulates protein phosphatase 1 Glc7p |
genetic |
1 |
1 |
1 |
Dosage Rescue |
PBP4 |
YDL053C |
Pbp1p binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YRA1 |
YDR381W |
Nuclear polyadenylated RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RVS167 |
YDR388W |
Calmodulin-binding actin-associated protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MYG1 |
YER156C |
Protein involved in mitochondrial function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
UBA1 |
YKL210W |
Ubiquitin activating enzyme (E1) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
KAP95 |
YLR347C |
Karyopherin beta |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
OTU2 |
YHL013C |
Protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
YMR262W |
YMR262W |
Protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
SIS1 |
YNL007C |
Type II HSP40 co-chaperone that interacts with the HSP70 protein Ssa1p |
physical |
1 |
1 |
1 |
Biochemical Activity |
YJL218W |
YJL218W |
Mitochondrial protein, putative acetyltransferase |
physical |
1 |
1 |
1 |
Biochemical Activity |
SCP160 |
YJL080C |
Essential RNA-binding G protein effector of mating response pathway |
physical |
1 |
1 |
1 |
Biochemical Activity |
NAP1 |
YKR048C |
Histone chaperone and assembly chaperone for Rps6a/b |
physical |
1 |
1 |
1 |
Biochemical Activity |
STM1 |
YLR150W |
Protein required for optimal translation under nutrient stress |
physical |
1 |
1 |
1 |
Biochemical Activity |
RDS2 |
YPL133C |
Transcription factor involved in regulating gluconeogenesis |
physical |
1 |
1 |
1 |
Biochemical Activity |
UTP25 |
YIL091C |
Nucleolar protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
TEF2 |
YBR118W |
Translational elongation factor EF-1 alpha |
physical |
1 |
1 |
1 |
Biochemical Activity |
MDH3 |
YDL078C |
Peroxisomal malate dehydrogenase |
physical |
1 |
1 |
1 |
Biochemical Activity |
YBL055C |
YBL055C |
3'-->5' exonuclease and endonuclease with a possible role in apoptosis |
physical |
1 |
1 |
1 |
Biochemical Activity |
TRM1 |
YDR120C |
tRNA methyltransferase |
physical |
1 |
1 |
1 |
Biochemical Activity |
RGC1 |
YPR115W |
Putative regulator of the Fps1p glycerol channel |
physical |
1 |
1 |
1 |
Biochemical Activity |
PCS60 |
YBR222C |
Oxalyl-CoA synthetase |
physical |
1 |
1 |
1 |
Biochemical Activity |
SKA1 |
YKL023W |
SKI complex-associated protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
UBP7 |
YIL156W |
Ubiquitin-specific protease that cleaves ubiquitin-protein fusions |
physical |
1 |
1 |
1 |
Biochemical Activity |
RSA4 |
YCR072C |
Ribosomal large subunit (60S) assembly factor |
physical |
1 |
1 |
1 |
Biochemical Activity |
YNG2 |
YHR090C |
Subunit of NuA4, an essential histone acetyltransferase complex |
physical |
1 |
1 |
1 |
Biochemical Activity |
RSP5 |
YER125W |
NEDD4 family E3 ubiquitin ligase |
physical |
1 |
1 |
1 |
Biochemical Activity |
RSP5 |
YER125W |
NEDD4 family E3 ubiquitin ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MVP1 |
YMR004W |
Protein required for sorting proteins to the vacuole |
physical |
1 |
1 |
1 |
Biochemical Activity |
MOB1 |
YIL106W |
Component of the mitotic exit network |
physical |
1 |
1 |
1 |
Co-localization |
SLX5 |
YDL013W |
Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex |
physical |
1 |
1 |
1 |
Two-hybrid |
SLX5 |
YDL013W |
Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
KNS1 |
YLL019C |
Protein kinase involved in negative regulation of PolIII transcription |
physical |
1 |
1 |
1 |
Two-hybrid |
OKP1 |
YGR179C |
Outer kinetochore protein required for accurate chromosome segregation |
physical |
1 |
1 |
1 |
Two-hybrid |
MAD3 |
YJL013C |
Subunit of spindle-assembly checkpoint complex |
physical |
1 |
1 |
1 |
Biochemical Activity |
NBL1 |
YHR199C-A |
Subunit of the conserved chromosomal passenger complex (CPC) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SPC34 |
YKR037C |
Essential subunit of the Dam1 complex (aka DASH complex) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PSE1 |
YMR308C |
Karyopherin/importin that interacts with the nuclear pore complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
YCS4 |
YLR272C |
Subunit of the condensin complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MPD1 |
YOR288C |
Member of the protein disulfide isomerase (PDI) family |
physical |
1 |
1 |
1 |
Reconstituted Complex |
RNA1 |
YMR235C |
GTPase activating protein (GAP) for Gsp1p |
physical |
1 |
1 |
1 |
Reconstituted Complex |
RNA1 |
YMR235C |
GTPase activating protein (GAP) for Gsp1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL7A |
YGL076C |
Ribosomal 60S subunit protein L7A |
physical |
1 |
1 |
1 |
Reconstituted Complex |
SCT1 |
YBL011W |
Glycerol 3-phosphate/dihydroxyacetone phosphate sn-1 acyltransferase |
physical |
1 |
1 |
1 |
Reconstituted Complex |
SPT8 |
YLR055C |
Subunit of the SAGA transcriptional regulatory complex |
physical |
1 |
1 |
1 |
Reconstituted Complex |
VPS75 |
YNL246W |
NAP family histone chaperone |
physical |
1 |
1 |
1 |
Reconstituted Complex |
MRX3 |
YBL095W |
Protein that associates with mitochondrial ribosome |
physical |
1 |
1 |
1 |
Reconstituted Complex |
YCF1 |
YDR135C |
Vacuolar glutathione S-conjugate transporter |
physical |
1 |
1 |
1 |
Reconstituted Complex |
MRX19 |
YDL183C |
Protein that may form an active mitochondrial KHE system |
physical |
1 |
1 |
1 |
Reconstituted Complex |
YGR130C |
YGR130C |
Component of the eisosome with unknown function |
physical |
1 |
1 |
1 |
Reconstituted Complex |
PEX35 |
YGR168C |
Regulator of peroxisome abundance |
physical |
1 |
1 |
1 |
Reconstituted Complex |
YPL150W |
YPL150W |
Protein kinase of unknown cellular role |
physical |
1 |
1 |
1 |
Reconstituted Complex |
MIF2 |
YKL089W |
Centromeric CDEIII region binding protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
MIF2 |
YKL089W |
Centromeric CDEIII region binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
RGD1 |
YBR260C |
GTPase-activating protein (RhoGAP) for Rho3p and Rho4p |
physical |
1 |
1 |
1 |
Biochemical Activity |
SHE1 |
YBL031W |
Mitotic spindle protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
SHE1 |
YBL031W |
Mitotic spindle protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
VAM6 |
YDL077C |
Guanine nucleotide exchange factor for the GTPase Gtr1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RAD52 |
YML032C |
Protein involved in homologous recombination |
physical |
1 |
1 |
1 |
Biochemical Activity |
SPT16 |
YGL207W |
Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SCD5 |
YOR329C |
Protein required for normal actin organization and endocytosis |
genetic |
1 |
1 |
1 |
Dosage Rescue |
SOL1 |
YNR034W |
Protein with a possible role in tRNA export |
genetic |
1 |
1 |
1 |
Dosage Rescue |
SOL2 |
YCR073W-A |
Protein with a possible role in tRNA export |
genetic |
1 |
1 |
1 |
Dosage Rescue |
PEX31 |
YGR004W |
Peroxisomal integral membrane protein |
genetic |
1 |
1 |
1 |
Dosage Rescue |
KIN2 |
YLR096W |
S/T protein kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
PPQ1 |
YPL179W |
Protein phosphatase that regulates the mating response |
genetic |
1 |
1 |
1 |
Negative Genetic |
MTW1 |
YAL034W-A |
Essential component of the MIND kinetochore complex |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
RAD53 |
YPL153C |
DNA damage response kinase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
LDB19 |
YOR322C |
Alpha-arrestin, Ub-ligase adaptor for Rsp5p |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
RTT103 |
YDR289C |
Protein involved in transcription termination by RNA polymerase II |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
MDM20 |
YOL076W |
Non-catalytic subunit of the NatB N-terminal acetyltransferase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
VIK1 |
YPL253C |
Protein that forms a kinesin-14 heterodimeric motor with Kar3p |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
KIN3 |
YAR018C |
Nonessential serine/threonine protein kinase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RIM101 |
YHL027W |
Cys2His2 zinc-finger transcriptional repressor |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
KIP1 |
YBL063W |
Kinesin-related motor protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MCD1 |
YDL003W |
Essential alpha-kleisin subunit of the cohesin complex |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
KIP3 |
YGL216W |
Kinesin-related antiparallel sliding motor protein |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
TOR1 |
YJR066W |
PIK-related protein kinase and rapamycin target |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
SPC105 |
YGL093W |
Subunit of a kinetochore-microtubule binding complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
SET4 |
YJL105W |
Chromatin-associated protein involved in control of stress response |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
SET3 |
YKR029C |
Defining member of the SET3 histone deacetylase complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
PAF1 |
YBR279W |
Component of the Paf1p complex involved in transcription elongation |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
RAD6 |
YGL058W |
Ubiquitin-conjugating enzyme (E2) |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
SCM3 |
YDL139C |
Nonhistone component of centromeric chromatin |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YBP2 |
YGL060W |
Central kinetochore associated protein |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
PDE2 |
YOR360C |
High-affinity cyclic AMP phosphodiesterase |
genetic |
1 |
1 |
1 |
Dosage Rescue |
TAF1 |
YGR274C |
TFIID subunit, involved in RNA pol II transcription initiation |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
TTI1 |
YKL033W |
Subunit of the ASTRA complex, involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Negative Genetic |
SGO1 |
YOR073W |
Component of the spindle checkpoint |
genetic |
1 |
1 |
1 |
Dosage Rescue |
NUP53 |
YMR153W |
FG-nucleoporin component of central core of nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
SEC27 |
YGL137W |
Essential beta'-coat protein of the COPI coatomer |
genetic |
1 |
1 |
1 |
Positive Genetic |
YKT6 |
YKL196C |
Vesicle membrane protein (v-SNARE) with acyltransferase activity |
genetic |
1 |
1 |
1 |
Positive Genetic |
LAS17 |
YOR181W |
Actin assembly factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
RFC1 |
YOR217W |
Subunit of heteropentameric Replication factor C (RF-C) |
genetic |
1 |
1 |
1 |
Positive Genetic |
SGV1 |
YPR161C |
Cyclin (Bur2p)-dependent protein kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
SNF5 |
YBR289W |
Subunit of the SWI/SNF chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
YCR023C |
YCR023C |
Vacuolar membrane protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
THR4 |
YCR053W |
Threonine synthase |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPN4 |
YDL020C |
Transcription factor that stimulates expression of proteasome genes |
genetic |
1 |
1 |
1 |
Positive Genetic |
NRG1 |
YDR043C |
Transcriptional repressor |
genetic |
1 |
1 |
1 |
Positive Genetic |
SNF1 |
YDR477W |
AMP-activated S/T protein kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
PUF6 |
YDR496C |
Pumilio-homology domain protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
MRM2 |
YGL136C |
Mitochondrial 2' O-ribose methyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
MIR1 |
YJR077C |
Mitochondrial phosphate carrier |
genetic |
1 |
1 |
1 |
Positive Genetic |
SAC1 |
YKL212W |
Phosphatidylinositol phosphate phosphatase |
genetic |
1 |
1 |
1 |
Positive Genetic |
YRA2 |
YKL214C |
Member of the REF (RNA and export factor binding proteins) family |
genetic |
1 |
1 |
1 |
Positive Genetic |
SDH2 |
YLL041C |
Iron-sulfur protein subunit of succinate dehydrogenase |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPS0B |
YLR048W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
SND2 |
YLR065C |
Protein involved in SRP-independent targeting of substrates to the ER |
genetic |
1 |
1 |
1 |
Positive Genetic |
YLR225C |
YLR225C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPS1B |
YML063W |
Ribosomal protein of the small (40S) subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
UBP8 |
YMR223W |
Ubiquitin-specific protease component of the SAGA acetylation complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
SIW14 |
YNL032W |
Inositol phosphatase involved in inositol pyrophosphate metabolism |
genetic |
1 |
1 |
1 |
Positive Genetic |
MKT1 |
YNL085W |
Protein similar to nucleases that forms a complex with Pbp1p |
genetic |
1 |
1 |
1 |
Positive Genetic |
VPS27 |
YNR006W |
Endosomal protein that forms a complex with Hse1p |
genetic |
1 |
1 |
1 |
Positive Genetic |
TRM11 |
YOL124C |
Catalytic subunit of adoMet-dependent tRNA methyltransferase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
SRO7 |
YPR032W |
Effector of Rab GTPase Sec4p |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPL43A |
YPR043W |
Ribosomal 60S subunit protein L43A |
genetic |
1 |
1 |
1 |
Positive Genetic |
YPR089W |
YPR089W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
VMA9 |
YCL005W-A |
Vacuolar H+ ATPase subunit e of the V-ATPase V0 subcomplex |
genetic |
1 |
1 |
1 |
Positive Genetic |
STP22 |
YCL008C |
Component of the ESCRT-I complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
VMA8 |
YEL051W |
Subunit D of the V1 peripheral membrane domain of V-ATPase |
genetic |
1 |
1 |
1 |
Positive Genetic |
SLX9 |
YGR081C |
Protein required for pre-rRNA processing |
genetic |
1 |
1 |
1 |
Positive Genetic |
RNR4 |
YGR180C |
Ribonucleotide-diphosphate reductase (RNR) small subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
PER33 |
YLR064W |
Protein that localizes to the endoplasmic reticulum |
genetic |
1 |
1 |
1 |
Positive Genetic |
YLR154C-H |
YLR154C-H |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
MIN3 |
YMR182W-A |
Mitochondrial protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
MRE11 |
YMR224C |
Nuclease subunit of the MRX complex with Rad50p and Xrs2p |
genetic |
1 |
1 |
1 |
Positive Genetic |
MCK1 |
YNL307C |
Dual-specificity ser/thr and tyrosine protein kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
REB1 |
YBR049C |
RNA polymerase I enhancer binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPG1 |
YBR079C |
eIF3a subunit of the eukaryotic translation initiation factor 3 (eIF3) |
genetic |
1 |
1 |
1 |
Negative Genetic |
MED8 |
YBR193C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRP5 |
YBR237W |
RNA helicase in the DEAD-box family |
genetic |
1 |
1 |
1 |
Negative Genetic |
QRI1 |
YDL103C |
UDP-N-acetylglucosamine pyrophosphorylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
KRS1 |
YDR037W |
Lysyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
TPI1 |
YDR050C |
Triose phosphate isomerase, abundant glycolytic enzyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS13 |
YDR064W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
TAF12 |
YDR145W |
Subunit (61/68 kDa) of TFIID and SAGA complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
TAF10 |
YDR167W |
Subunit (145 kDa) of TFIID and SAGA complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
SCC2 |
YDR180W |
Subunit of cohesin loading factor (Scc2p-Scc4p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPP41 |
YDR464W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
RBA50 |
YDR527W |
Protein involved in transcription |
genetic |
1 |
1 |
1 |
Negative Genetic |
WBP1 |
YEL002C |
Beta subunit of the oligosaccharyl transferase glycoprotein complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
POL5 |
YEL055C |
Protein involved in 60S assembly and pre-40S AFs recycling |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRP22 |
YER013W |
DEAH-box RNA-dependent ATPase/ATP-dependent RNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SRB4 |
YER022W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
LCP5 |
YER127W |
Essential protein involved in maturation of 18S rRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS2 |
YGL123W |
Protein component of the small (40S) subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
SWC4 |
YGR002C |
Component of the Swr1p complex that incorporates Htz1p into chromatin |
genetic |
1 |
1 |
1 |
Negative Genetic |
TFG2 |
YGR005C |
TFIIF (Transcription Factor II) middle subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
NUP57 |
YGR119C |
FG-nucleoporin component of central core of the nuclear pore complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
UTP8 |
YGR128C |
Nucleolar protein required for export of tRNAs from the nucleus |
genetic |
1 |
1 |
1 |
Negative Genetic |
MTR3 |
YGR158C |
Exosome non-catalytic core component |
genetic |
1 |
1 |
1 |
Negative Genetic |
NOP19 |
YGR251W |
Ribosome biogenesis factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPB3 |
YIL021W |
RNA polymerase II third largest subunit B44 |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC11 |
YIR022W |
18kDa catalytic subunit of the Signal Peptidase Complex (SPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
TIM54 |
YJL054W |
Component of the mitochondrial TIM22 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
UTP18 |
YJL069C |
Small-subunit processome protein involved in pre-18S rRNA maturation |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPC42 |
YKL042W |
Central plaque component of spindle pole body (SPB) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SNU114 |
YKL173W |
GTPase component of U5 snRNP involved in mRNA splicing via spliceosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
SFI1 |
YLL003W |
Centrin (Cdc31p)-binding protein required for SPB duplication |
genetic |
1 |
1 |
1 |
Negative Genetic |
SOF1 |
YLL011W |
Protein required for biogenesis of 40S (small) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL10 |
YLR075W |
Ribosomal 60S subunit protein L10 |
genetic |
1 |
1 |
1 |
Negative Genetic |
MSL5 |
YLR116W |
Component of commitment complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SMD2 |
YLR275W |
Core Sm protein Sm D2 |
genetic |
1 |
1 |
1 |
Negative Genetic |
YHC1 |
YLR298C |
Component of the U1 snRNP complex required for pre-mRNA splicing |
genetic |
1 |
1 |
1 |
Negative Genetic |
TAD3 |
YLR316C |
Subunit of tRNA-specific adenosine-34 deaminase |
genetic |
1 |
1 |
1 |
Negative Genetic |
TAF13 |
YML098W |
TFIID subunit (19 kDa) |
genetic |
1 |
1 |
1 |
Negative Genetic |
RNT1 |
YMR239C |
Nuclear dsRNA-specific ribonuclease (RNase III) |
genetic |
1 |
1 |
1 |
Negative Genetic |
NOP2 |
YNL061W |
rRNA m5C methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPC19 |
YNL113W |
RNA polymerase subunit AC19 |
genetic |
1 |
1 |
1 |
Negative Genetic |
PGA2 |
YNL149C |
Essential protein required for maturation of Gas1p and Pho8p |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS3 |
YNL178W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
PBR1 |
YNL181W |
Putative oxidoreductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
NAR1 |
YNL240C |
Subunit of the cytosolic iron-sulfur (FeS) protein assembly machinery |
genetic |
1 |
1 |
1 |
Negative Genetic |
POP3 |
YNL282W |
Subunit of both RNase MRP and nuclear RNase P |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRP2 |
YNR011C |
RNA-dependent DExD/H-box ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPB11 |
YOL005C |
RNA polymerase II subunit B12.5 |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS15 |
YOL040C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
RIO1 |
YOR119C |
Serine kinase involved in cell cycle regulation and rDNA integrity |
genetic |
1 |
1 |
1 |
Negative Genetic |
TOA1 |
YOR194C |
TFIIA large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPB10 |
YOR210W |
RNA polymerase subunit ABC10-beta |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPB8 |
YOR224C |
RNA polymerase subunit ABC14.5 |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPT4 |
YOR259C |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
NOP58 |
YOR310C |
Protein involved in producing mature rRNAs and snoRNAs |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPA43 |
YOR340C |
RNA polymerase I subunit A43 |
genetic |
1 |
1 |
1 |
Negative Genetic |
SWI1 |
YPL016W |
Subunit of the SWI/SNF chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPB5 |
YBR154C |
RNA polymerase subunit ABC27 |
genetic |
1 |
1 |
1 |
Negative Genetic |
POP7 |
YBR167C |
Subunit of RNase MRP, nuclear RNase P and telomerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
NSE4 |
YDL105W |
Component of the SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPO21 |
YDL140C |
RNA polymerase II largest subunit B220 |
genetic |
1 |
1 |
1 |
Negative Genetic |
NOP14 |
YDL148C |
Nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
PDC2 |
YDR081C |
Transcription factor for thiamine-regulated genes |
genetic |
1 |
1 |
1 |
Negative Genetic |
TRS23 |
YDR246W |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
1 |
1 |
1 |
Negative Genetic |
MOB2 |
YFL034C-B |
Activator of Cbk1p kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ORC6 |
YHR118C |
Subunit of the origin recognition complex (ORC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRP19 |
YLL036C |
Splicing factor associated with the spliceosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC65 |
YML105C |
Subunit of the signal recognition particle (SRP) |
genetic |
1 |
1 |
1 |
Negative Genetic |
PDS5 |
YMR076C |
Cohesion maintenance factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
LCB1 |
YMR296C |
Component of serine palmitoyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SGT1 |
YOR057W |
Cochaperone protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
MCM1 |
YMR043W |
Transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
LIP1 |
YMR298W |
Ceramide synthase subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPC34 |
YNR003C |
RNA polymerase III subunit C34 |
genetic |
1 |
1 |
1 |
Negative Genetic |
SWD1 |
YAR003W |
Subunit of the COMPASS (Set1C) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ISW1 |
YBR245C |
ATPase subunit of imitation-switch (ISWI) class chromatin remodelers |
genetic |
1 |
1 |
1 |
Negative Genetic |
RRT2 |
YBR246W |
Methylesterase performing penultimate step of diphthamide biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
YCL002C |
YCL002C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
RVS161 |
YCR009C |
Amphiphysin-like lipid raft protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
PTC6 |
YCR079W |
Mitochondrial type 2C protein phosphatase (PP2C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS16B |
YDL083C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPA14 |
YDR156W |
RNA polymerase I subunit A14 |
genetic |
1 |
1 |
1 |
Negative Genetic |
SWR1 |
YDR334W |
Swi2/Snf2-related ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SDC1 |
YDR469W |
Subunit of the COMPASS (Set1C) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS24A |
YER074W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPT2 |
YER161C |
Protein involved in negative regulation of transcription |
genetic |
1 |
1 |
1 |
Negative Genetic |
YIP4 |
YGL198W |
Protein that interacts with Rab GTPases |
genetic |
1 |
1 |
1 |
Negative Genetic |
YGR050C |
YGR050C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YGR210C |
YGR210C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
RNH70 |
YGR276C |
3'-5' exoribonuclease |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS27B |
YHR021C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
KSP1 |
YHR082C |
Serine/threonine protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SDS3 |
YIL084C |
Component of the Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RRD1 |
YIL153W |
Peptidyl-prolyl cis/trans-isomerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPE1 |
YJL121C |
D-ribulose-5-phosphate 3-epimerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
LSM1 |
YJL124C |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
MET5 |
YJR137C |
Sulfite reductase beta subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
PAN3 |
YKL025C |
Essential subunit of the Pan2p-Pan3p poly(A)-ribonuclease complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
TEF4 |
YKL081W |
Gamma subunit of translational elongation factor eEF1B |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS27A |
YKL156W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
UBI4 |
YLL039C |
Ubiquitin |
genetic |
1 |
1 |
1 |
Negative Genetic |
SIC1 |
YLR079W |
Cyclin-dependent kinase inhibitor (CKI) |
genetic |
1 |
1 |
1 |
Negative Genetic |
YLR415C |
YLR415C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
RSF1 |
YMR030W |
Protein required for respiratory growth |
genetic |
1 |
1 |
1 |
Negative Genetic |
MLO1 |
YMR252C |
Mitochondrial protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
LDS2 |
YOL047C |
Protein Involved in spore wall assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
STI1 |
YOR027W |
Evolutionarily-conserved Hsp90 cochaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
MSA1 |
YOR066W |
Activator of G1-specific transcription factors MBF and SBF |
genetic |
1 |
1 |
1 |
Negative Genetic |
KAR3 |
YPR141C |
Minus-end-directed microtubule motor |
genetic |
1 |
1 |
1 |
Negative Genetic |
OPT2 |
YPR194C |
Oligopeptide transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
LTE1 |
YAL024C |
Protein similar to GDP/GTP exchange factors |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS11B |
YBR048W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
YAL063C-A |
YAL063C-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YBL071C-B |
YBL071C-B |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL23A |
YBL087C |
Ribosomal 60S subunit protein L23A |
genetic |
1 |
1 |
1 |
Negative Genetic |
KAP104 |
YBR017C |
Transportin or cytosolic karyopherin beta 2 |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPP1B |
YDL130W |
Ribosomal protein P1 beta |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRPL1 |
YDR116C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
MFB1 |
YDR219C |
Mitochondria-associated F-box protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPT3 |
YDR392W |
Subunit of the SAGA and SAGA-like transcriptional regulatory complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL12B |
YDR418W |
Ribosomal 60S subunit protein L12B |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS72 |
YDR485C |
Htz1p-binding component of the SWR1 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
VMA3 |
YEL027W |
Proteolipid subunit c of the V0 domain of vacuolar H(+)-ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL12A |
YEL054C |
Ribosomal 60S subunit protein L12A |
genetic |
1 |
1 |
1 |
Negative Genetic |
UBC6 |
YER100W |
Ubiquitin-conjugating enzyme involved in ERAD |
genetic |
1 |
1 |
1 |
Negative Genetic |
KAP123 |
YER110C |
Karyopherin beta |
genetic |
1 |
1 |
1 |
Negative Genetic |
MET10 |
YFR030W |
Subunit alpha of assimilatory sulfite reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL2A |
YFR031C-A |
Ribosomal 60S subunit protein L2A |
genetic |
1 |
1 |
1 |
Negative Genetic |
ORM1 |
YGR038W |
Protein that mediates sphingolipid homeostasis |
genetic |
1 |
1 |
1 |
Negative Genetic |
YGR111W |
YGR111W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YGR122W |
YGR122W |
Protein that may be involved in pH regulation |
genetic |
1 |
1 |
1 |
Negative Genetic |
TOS2 |
YGR221C |
Protein involved in localization of Cdc24p to the site of bud growth |
genetic |
1 |
1 |
1 |
Negative Genetic |
SAY1 |
YGR263C |
Sterol deacetylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
OCA5 |
YHL029C |
Cytoplasmic protein required for replication of Brome mosaic virus |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRP8 |
YHR165C |
Component of U4/U6-U5 snRNP complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
LIA1 |
YJR070C |
Deoxyhypusine hydroxylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MNS1 |
YJR131W |
Alpha-1,2-mannosidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MUD2 |
YKL074C |
Protein involved in early pre-mRNA splicing |
genetic |
1 |
1 |
1 |
Negative Genetic |
TIS11 |
YLR136C |
mRNA-binding protein expressed during iron starvation |
genetic |
1 |
1 |
1 |
Negative Genetic |
YLR264C-A |
YLR264C-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS30A |
YLR287C-A |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL38 |
YLR325C |
Ribosomal 60S subunit protein L38 |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS25B |
YLR333C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL26A |
YLR344W |
Ribosomal 60S subunit protein L26A |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS1A |
YLR441C |
Ribosomal protein of the small (40S) subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS17A |
YML024W |
Ribosomal protein 51 (rp51) of the small (40s) subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS71 |
YML041C |
Nucleosome-binding component of the SWR1 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL6A |
YML073C |
Ribosomal 60S subunit protein L6A |
genetic |
1 |
1 |
1 |
Negative Genetic |
YMR001C-A |
YMR001C-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS10B |
YMR230W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
SLM2 |
YNL047C |
Phosphoinositide PI4,5P(2) binding protein, forms a complex with Slm1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
OCA2 |
YNL056W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
MPP6 |
YNR024W |
Nuclear exosome-associated RNA binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS19A |
YOL121C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
MDH2 |
YOL126C |
Cytoplasmic malate dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
TSR3 |
YOR006C |
Protein required for 20S pre-rRNA processing |
genetic |
1 |
1 |
1 |
Negative Genetic |
YOR072W-B |
YOR072W-B |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS17 |
YOR132W |
Subunit of the membrane-associated retromer complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SLK19 |
YOR195W |
Kinetochore-associated protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRM1 |
YOR201C |
Ribose methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RFM1 |
YOR279C |
Component of the Sum1p-Rfm1p-Hst1p complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
MBP1 |
YDL056W |
Transcription factor |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
SWI4 |
YER111C |
DNA binding component of the SBF complex (Swi4p-Swi6p) |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
TOP2 |
YNL088W |
Topoisomerase II |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
YCG1 |
YDR325W |
Subunit of the condensin complex |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
UBP3 |
YER151C |
Ubiquitin-specific protease that cleaves Ub-protein fusions |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
KIP2 |
YPL155C |
Kinesin-related motor protein involved in mitotic spindle positioning |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
UBC4 |
YBR082C |
Ubiquitin-conjugating enzyme (E2) |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
SWE1 |
YJL187C |
Protein kinase that regulates the G2/M transition |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
DOC1 |
YGL240W |
Processivity factor |
genetic |
1 |
1 |
1 |
Dosage Lethality |
CDC21 |
YOR074C |
Thymidylate synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
CSE4 |
YKL049C |
Centromeric histone H3-like protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
BFR1 |
YOR198C |
Component of mRNP complexes associated with polyribosomes |
physical |
1 |
1 |
1 |
Biochemical Activity |
CLB5 |
YPR120C |
B-type cyclin involved in DNA replication during S phase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
ECO1 |
YFR027W |
Acetyltransferase required for sister chromatid cohesion |
genetic |
1 |
1 |
1 |
Negative Genetic |
CBF2 |
YGR140W |
Essential kinetochore protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
GLN3 |
YER040W |
Transcriptional activator in nitrogen catabolite repression system |
genetic |
1 |
1 |
1 |
Negative Genetic |
GYP1 |
YOR070C |
Cis-golgi GTPase-activating protein (GAP) for yeast Rabs |
genetic |
1 |
1 |
1 |
Positive Genetic |
ABF1 |
YKL112W |
DNA binding protein with possible chromatin-reorganizing activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
FCP1 |
YMR277W |
Carboxy-terminal domain (CTD) phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
BPT1 |
YLL015W |
ABC type transmembrane transporter of MRP/CFTR family |
genetic |
1 |
1 |
1 |
Negative Genetic |
DPH6 |
YLR143W |
Diphthamide synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
GPR1 |
YDL035C |
Plasma membrane G protein coupled receptor (GPCR) |
genetic |
1 |
1 |
1 |
Positive Genetic |
ARK1 |
YNL020C |
Ser/Thr protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
HHT2 |
YNL031C |
Histone H3 |
physical |
1 |
1 |
1 |
Biochemical Activity |
ASH1 |
YKL185W |
Component of the Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CYB2 |
YML054C |
Cytochrome b2 (L-lactate cytochrome-c oxidoreductase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
CIN2 |
YPL241C |
GTPase-activating protein (GAP) for Cin4p |
genetic |
1 |
1 |
1 |
Negative Genetic |
EAF7 |
YNL136W |
Subunit of the NuA4 histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
FOX2 |
YKR009C |
3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA hydratase |
physical |
1 |
1 |
1 |
Biochemical Activity |
BOP3 |
YNL042W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
CNN1 |
YFR046C |
Kinetochore protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
CAT2 |
YML042W |
Carnitine acetyl-CoA transferase |
physical |
1 |
1 |
1 |
Biochemical Activity |
ASE1 |
YOR058C |
Mitotic spindle midzone-localized microtubule bundling protein |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
FCF2 |
YLR051C |
Nucleolar protein involved in the early steps of 35S rRNA processing |
genetic |
1 |
1 |
1 |
Negative Genetic |
AIM22 |
YJL046W |
Lipoate-protein ligase |
genetic |
1 |
1 |
1 |
Positive Genetic |
ATP12 |
YJL180C |
Assembly factor for F1 sector of mitochondrial F1F0 ATP synthase |
genetic |
1 |
1 |
1 |
Positive Genetic |
CGI121 |
YML036W |
Component of the EKC/KEOPS complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CYK3 |
YDL117W |
SH3-domain protein located in the bud neck and cytokinetic actin ring |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
IDP3 |
YNL009W |
Peroxisomal NADP-dependent isocitrate dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ACL4 |
YDR161W |
Specific assembly chaperone for ribosomal protein Rpl4a/Rpl4b |
genetic |
1 |
1 |
1 |
Negative Genetic |
DEG1 |
YFL001W |
tRNA:pseudouridine synthase |
physical |
1 |
1 |
1 |
Biochemical Activity |
AIM11 |
YER093C-A |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
ALG6 |
YOR002W |
ER-luminal alpha 1,3 glucosyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
DOT5 |
YIL010W |
Nuclear thiol peroxidase |
physical |
1 |
1 |
1 |
Reconstituted Complex |
EOS1 |
YNL080C |
Protein involved in N-glycosylation |
genetic |
1 |
1 |
1 |
Negative Genetic |
GPI19 |
YDR437W |
Subunit of GPI-GlcNAc transferase involved in synthesis of GlcNAc-PI |
genetic |
1 |
1 |
1 |
Negative Genetic |
COQ2 |
YNR041C |
Para hydroxybenzoate polyprenyl transferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
HXT3 |
YDR345C |
Low affinity glucose transporter of the major facilitator superfamily |
genetic |
1 |
1 |
1 |
Negative Genetic |
GRX3 |
YDR098C |
Glutathione-dependent oxidoreductase |
physical |
1 |
1 |
1 |
Reconstituted Complex |
CEM1 |
YER061C |
Mitochondrial beta-keto-acyl synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
BRR6 |
YGL247W |
Essential nuclear envelope integral membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC8 |
YJR057W |
Nucleoside monophosphate and nucleoside diphosphate kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
COX20 |
YDR231C |
Mitochondrial inner membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
FYV7 |
YLR068W |
Nucleolar protein required for maturation of 18S rRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
CRD1 |
YDL142C |
Cardiolipin synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC1 |
YDR182W |
Putative mannose-ethanolamine phosphate phosphodiesterase |
genetic |
1 |
1 |
1 |
Negative Genetic |
GPI8 |
YDR331W |
Catalytic subunit of the ER membrane GPI transamidase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
BCD1 |
YHR040W |
Essential protein required for the accumulation of box C/D snoRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
DPA10 |
YLR307C-A |
Putative mitochondrial protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
APQ12 |
YIL040W |
Nuclear envelope/ER integral membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
HES1 |
YOR237W |
Protein implicated in the regulation of ergosterol biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |