CDC28 |
YBR160W |
Cyclin-dependent kinase (CDK) catalytic subunit |
physical |
13 |
3 |
11 |
Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Affinity Capture-Western, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity |
CDC4 |
YFL009W |
F-box protein required for both the G1/S and G2/M phase transitions |
physical |
8 |
2 |
8 |
Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Affinity Capture-Western, Two-hybrid |
ORC1 |
YML065W |
Largest subunit of the origin recognition complex |
physical |
7 |
3 |
5 |
Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Two-hybrid, Two-hybrid, Reconstituted Complex, Reconstituted Complex |
ORC2 |
YBR060C |
Subunit of the origin recognition complex (ORC) |
physical |
6 |
3 |
6 |
Reconstituted Complex, Reconstituted Complex, Two-hybrid, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex |
SIC1 |
YLR079W |
Cyclin-dependent kinase inhibitor (CKI) |
genetic |
6 |
4 |
5 |
Dosage Rescue, Synthetic Lethality, Negative Genetic, Synthetic Lethality, Negative Genetic, Synthetic Growth Defect |
MCM2 |
YBL023C |
Protein involved in DNA replication |
physical |
6 |
3 |
5 |
Reconstituted Complex, Two-hybrid, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex |
ORC6 |
YHR118C |
Subunit of the origin recognition complex (ORC) |
genetic |
6 |
3 |
5 |
Dosage Lethality, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic |
CDC14 |
YFR028C |
Protein phosphatase required for mitotic exit |
genetic |
6 |
4 |
4 |
Synthetic Growth Defect, Dosage Lethality, Synthetic Growth Defect, Dosage Rescue, Negative Genetic, Negative Genetic |
ORC5 |
YNL261W |
Subunit of the origin recognition complex (ORC) |
physical |
5 |
3 |
5 |
Affinity Capture-MS, Reconstituted Complex, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex |
MCM7 |
YBR202W |
Component of the Mcm2-7 hexameric helicase complex |
physical |
5 |
2 |
5 |
Reconstituted Complex, Co-localization, Co-localization, Co-localization, Reconstituted Complex |
CLB2 |
YPR119W |
B-type cyclin involved in cell cycle progression |
physical |
5 |
3 |
4 |
Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-Western |
MRC1 |
YCL061C |
S-phase checkpoint protein required for DNA replication |
genetic |
5 |
3 |
4 |
Dosage Lethality, Synthetic Rescue, Negative Genetic, Negative Genetic, Negative Genetic |
CDC4 |
YFL009W |
F-box protein required for both the G1/S and G2/M phase transitions |
genetic |
4 |
3 |
3 |
Dosage Lethality, Synthetic Lethality, Positive Genetic, Positive Genetic |
RAD24 |
YER173W |
Checkpoint protein |
genetic |
4 |
2 |
3 |
Dosage Lethality, Negative Genetic, Negative Genetic, Negative Genetic |
SWI5 |
YDR146C |
Transcription factor that recruits Mediator and Swi/Snf complexes |
genetic |
4 |
2 |
3 |
Dosage Rescue, Negative Genetic, Negative Genetic, Negative Genetic |
RAD9 |
YDR217C |
DNA damage-dependent checkpoint protein |
genetic |
4 |
2 |
3 |
Dosage Lethality, Negative Genetic, Negative Genetic, Negative Genetic |
RAD17 |
YOR368W |
Checkpoint protein |
genetic |
4 |
2 |
3 |
Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic |
SIR2 |
YDL042C |
Conserved NAD+ dependent histone deacetylase of the Sirtuin family |
genetic |
4 |
2 |
3 |
Phenotypic Suppression, Synthetic Rescue, Phenotypic Suppression, Synthetic Rescue |
HST3 |
YOR025W |
Sirtuin, histone H3 deacetylase |
genetic |
4 |
2 |
3 |
Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic |
BRE1 |
YDL074C |
E3 ubiquitin ligase |
genetic |
4 |
3 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Rescue, Negative Genetic |
MCK1 |
YNL307C |
Dual-specificity ser/thr and tyrosine protein kinase |
physical |
4 |
3 |
2 |
Two-hybrid, Affinity Capture-Western, Biochemical Activity, Biochemical Activity |
SWD1 |
YAR003W |
Subunit of the COMPASS (Set1C) complex |
genetic |
4 |
3 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Rescue, Negative Genetic |
ORC5 |
YNL261W |
Subunit of the origin recognition complex (ORC) |
genetic |
3 |
3 |
3 |
Dosage Rescue, Synthetic Growth Defect, Negative Genetic |
HHT1 |
YBR010W |
Histone H3 |
genetic |
3 |
3 |
3 |
Dosage Lethality, Synthetic Growth Defect, Synthetic Rescue |
MCM5 |
YLR274W |
Component of the Mcm2-7 hexameric helicase complex |
physical |
3 |
2 |
3 |
Co-localization, Co-localization, Affinity Capture-Western |
CTF18 |
YMR078C |
Subunit of a complex with Ctf8p |
genetic |
3 |
2 |
3 |
Synthetic Lethality, Negative Genetic, Negative Genetic |
CHL1 |
YPL008W |
Probable DNA helicase |
genetic |
3 |
2 |
3 |
Synthetic Growth Defect, Negative Genetic, Negative Genetic |
ORC3 |
YLL004W |
Subunit of the origin recognition complex (ORC) |
physical |
3 |
1 |
3 |
Reconstituted Complex, Reconstituted Complex, Reconstituted Complex |
ORC4 |
YPR162C |
Subunit of the origin recognition complex (ORC) |
physical |
3 |
1 |
3 |
Reconstituted Complex, Reconstituted Complex, Reconstituted Complex |
CLB5 |
YPR120C |
B-type cyclin involved in DNA replication during S phase |
genetic |
3 |
1 |
3 |
Synthetic Lethality, Synthetic Lethality, Synthetic Lethality |
IME2 |
YJL106W |
Serine/threonine protein kinase involved in activation of meiosis |
physical |
3 |
3 |
2 |
Two-hybrid, Affinity Capture-Western, Biochemical Activity |
CDH1 |
YGL003C |
Activator of anaphase-promoting complex/cyclosome (APC/C) |
genetic |
3 |
3 |
2 |
Dosage Rescue, Phenotypic Enhancement, Synthetic Lethality |
CDC14 |
YFR028C |
Protein phosphatase required for mitotic exit |
physical |
3 |
2 |
2 |
Affinity Capture-Western, Biochemical Activity, Biochemical Activity |
ORC2 |
YBR060C |
Subunit of the origin recognition complex (ORC) |
genetic |
3 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic, Negative Genetic |
CSM3 |
YMR048W |
Replication fork associated factor |
genetic |
3 |
2 |
2 |
Synthetic Rescue, Negative Genetic, Negative Genetic |
DDC1 |
YPL194W |
DNA damage checkpoint protein |
genetic |
3 |
2 |
2 |
Synthetic Lethality, Negative Genetic, Negative Genetic |
HHF1 |
YBR009C |
Histone H4 |
genetic |
3 |
2 |
2 |
Synthetic Rescue, Dosage Lethality, Synthetic Rescue |
SET1 |
YHR119W |
Histone methyltransferase, subunit of the COMPASS (Set1C) complex |
genetic |
3 |
2 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic |
BRE2 |
YLR015W |
Subunit of COMPASS (Set1C) complex |
genetic |
3 |
2 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic |
OCA5 |
YHL029C |
Cytoplasmic protein required for replication of Brome mosaic virus |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
HSC82 |
YMR186W |
Cytoplasmic chaperone of the Hsp90 family |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
IPI3 |
YNL182C |
Component of the Rix1 complex and pre-replicative complexes (pre-RCs) |
physical |
3 |
2 |
1 |
Affinity Capture-Western, Two-hybrid, Two-hybrid |
FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
2 |
2 |
2 |
chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments |
CDC28 |
YBR160W |
Cyclin-dependent kinase (CDK) catalytic subunit |
genetic |
2 |
2 |
2 |
Positive Genetic, Dosage Lethality |
CKS1 |
YBR135W |
Cyclin-dependent protein kinase regulatory subunit and adaptor |
physical |
2 |
2 |
2 |
Affinity Capture-Western, Reconstituted Complex |
CLB2 |
YPR119W |
B-type cyclin involved in cell cycle progression |
genetic |
2 |
2 |
2 |
Dosage Rescue, Dosage Lethality |
ORC1 |
YML065W |
Largest subunit of the origin recognition complex |
genetic |
2 |
2 |
2 |
Dosage Rescue, Negative Genetic |
WHI3 |
YNL197C |
RNA binding protein that modulates mRNA stability |
physical |
2 |
2 |
2 |
Protein-RNA, Affinity Capture-RNA |
TOM1 |
YDR457W |
E3 ubiquitin ligase of the hect-domain class |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Dosage Growth Defect |
ISW1 |
YBR245C |
ATPase subunit of imitation-switch (ISWI) class chromatin remodelers |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
RAD53 |
YPL153C |
DNA damage response kinase |
genetic |
2 |
2 |
2 |
Dosage Lethality, Synthetic Lethality |
CTF4 |
YPR135W |
Chromatin-associated protein |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Negative Genetic |
TOF1 |
YNL273W |
Subunit of a replication-pausing checkpoint complex |
genetic |
2 |
2 |
2 |
Synthetic Rescue, Negative Genetic |
MEC1 |
YBR136W |
Genome integrity checkpoint protein and PI kinase superfamily member |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Negative Genetic |
MRE11 |
YMR224C |
Nuclease subunit of the MRX complex with Rad50p and Xrs2p |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
SWI6 |
YLR182W |
Transcription cofactor |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Positive Genetic |
CHD1 |
YER164W |
Chromatin remodeler that regulates various aspects of transcription |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
HDA1 |
YNL021W |
Catalytic subunit of class II HDA1 histone deacetylase complex |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
NDT80 |
YHR124W |
Meiosis-specific transcription factor |
genetic |
2 |
2 |
2 |
Phenotypic Suppression, Negative Genetic |
POL2 |
YNL262W |
Catalytic subunit of DNA polymerase (II) epsilon |
genetic |
2 |
2 |
2 |
Negative Genetic, Positive Genetic |
RIM20 |
YOR275C |
Protein involved in proteolytic activation of Rim101p |
genetic |
2 |
2 |
2 |
Negative Genetic, Positive Genetic |
RPT1 |
YKL145W |
ATPase of the 19S regulatory particle of the 26S proteasome |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
TAH11 |
YJR046W |
DNA replication licensing factor |
physical |
2 |
1 |
2 |
Reconstituted Complex, Reconstituted Complex |
ORC6 |
YHR118C |
Subunit of the origin recognition complex (ORC) |
physical |
2 |
1 |
2 |
Reconstituted Complex, Reconstituted Complex |
OCA4 |
YCR095C |
Cytoplasmic protein required for replication of Brome mosaic virus |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RPS27B |
YHR021C |
Protein component of the small (40S) ribosomal subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SMA2 |
YML066C |
Meiosis-specific prospore membrane protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SIR3 |
YLR442C |
Silencing protein |
genetic |
2 |
1 |
2 |
Synthetic Rescue, Synthetic Rescue |
SWI4 |
YER111C |
DNA binding component of the SBF complex (Swi4p-Swi6p) |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
ERG3 |
YLR056W |
C-5 sterol desaturase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SRP1 |
YNL189W |
Karyopherin alpha homolog |
physical |
2 |
2 |
1 |
Reconstituted Complex, Protein-peptide |
ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
RPT1 |
YKL145W |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
MCM7 |
YBR202W |
Component of the Mcm2-7 hexameric helicase complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
MCM5 |
YLR274W |
Component of the Mcm2-7 hexameric helicase complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
HSF1 |
YGL073W |
Trimeric heat shock transcription factor |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
ORC3 |
YLL004W |
Subunit of the origin recognition complex (ORC) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
ORC4 |
YPR162C |
Subunit of the origin recognition complex (ORC) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
TOM1 |
YDR457W |
E3 ubiquitin ligase of the hect-domain class |
physical |
2 |
1 |
1 |
Affinity Capture-Western, Affinity Capture-Western |
DIA2 |
YOR080W |
Origin-binding F-box protein |
physical |
2 |
1 |
1 |
Affinity Capture-Western, Affinity Capture-Western |
RAD6 |
YGL058W |
Ubiquitin-conjugating enzyme (E2) |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
SPO11 |
YHL022C |
Meiosis-specific protein required for meiotic recombination |
genetic |
2 |
1 |
1 |
Phenotypic Suppression, Phenotypic Suppression |
POL12 |
YBL035C |
B subunit of DNA polymerase alpha-primase complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
CDC7 |
YDL017W |
S/T kinase and catalytic subunit of DDK (Dbf4-dependent kinase) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
POL3 |
YDL102W |
Catalytic subunit of DNA polymerase delta |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
PSF1 |
YDR013W |
Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
DBF4 |
YDR052C |
Regulatory subunit of Cdc7p-Dbf4p kinase complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
RPN1 |
YHR027C |
Non-ATPase base subunit of the 19S RP of the 26S proteasome |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
RPT4 |
YOR259C |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
MCM4 |
YPR019W |
Essential helicase component of heterohexameric MCM2-7 complexes |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
RTF1 |
YGL244W |
Subunit of RNAPII-associated chromatin remodeling Paf1 complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
DBF2 |
YGR092W |
Ser/Thr kinase involved in transcription and stress response |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
RIM13 |
YMR154C |
Calpain-like cysteine protease |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
APC5 |
YOR249C |
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
FKH2 |
YNL068C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
ChEC-Seq experiments |
GCR2 |
YNL199C |
Transcriptional activator of genes involved in glycolysis |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
HFI1 |
YPL254W |
Adaptor protein required for structural integrity of the SAGA complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
REB1 |
YBR049C |
RNA polymerase I enhancer binding protein |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
CDC28 |
YBR160W |
Cyclin-dependent kinase (CDK) catalytic subunit |
regulation |
1 |
1 |
1 |
quantitative mass spectrometry evidence |
NRG1 |
YDR043C |
Transcriptional repressor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SWI4 |
YER111C |
DNA binding component of the SBF complex (Swi4p-Swi6p) |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
ASH1 |
YKL185W |
Component of the Rpd3L histone deacetylase complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SWI6 |
YLR182W |
Transcription cofactor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
MBP1 |
YDL056W |
Transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
MCM1 |
YMR043W |
Transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
PUT3 |
YKL015W |
Transcriptional activator |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
CKS1 |
YBR135W |
Cyclin-dependent protein kinase regulatory subunit and adaptor |
regulation |
1 |
1 |
1 |
protein kinase assay evidence |
BMH1 |
YER177W |
14-3-3 protein, major isoform |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
ACC1 |
YNR016C |
Acetyl-CoA carboxylase, biotin containing enzyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
APC2 |
YLR127C |
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARC15 |
YIL062C |
Subunit of the ARP2/3 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
ARO1 |
YDR127W |
Pentafunctional arom protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC55 |
YGL190C |
Regulatory subunit B of protein phosphatase 2A (PP2A) |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
CDC16 |
YKL022C |
Subunit of the anaphase-promoting complex/cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC23 |
YHR166C |
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CKS1 |
YBR135W |
Cyclin-dependent protein kinase regulatory subunit and adaptor |
genetic |
1 |
1 |
1 |
Positive Genetic |
MCM2 |
YBL023C |
Protein involved in DNA replication |
genetic |
1 |
1 |
1 |
Negative Genetic |
ECM1 |
YAL059W |
Pre-ribosomal factor involved in 60S ribosomal protein subunit export |
physical |
1 |
1 |
1 |
Two-hybrid |
HSF1 |
YGL073W |
Trimeric heat shock transcription factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SEC39 |
YLR440C |
Component of the Dsl1p tethering complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SEC39 |
YLR440C |
Component of the Dsl1p tethering complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
LSB3 |
YFR024C-A |
Protein containing a C-terminal SH3 domain |
physical |
1 |
1 |
1 |
Two-hybrid |
YSC84 |
YHR016C |
Actin-binding protein |
physical |
1 |
1 |
1 |
Two-hybrid |
RVS167 |
YDR388W |
Calmodulin-binding actin-associated protein |
physical |
1 |
1 |
1 |
Two-hybrid |
DIA2 |
YOR080W |
Origin-binding F-box protein |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
MCK1 |
YNL307C |
Dual-specificity ser/thr and tyrosine protein kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
LSM1 |
YJL124C |
Lsm (Like Sm) protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
LSM1 |
YJL124C |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
RFM1 |
YOR279C |
Component of the Sum1p-Rfm1p-Hst1p complex |
physical |
1 |
1 |
1 |
Two-hybrid |
PSY2 |
YNL201C |
Subunit of protein phosphatase PP4 complex |
physical |
1 |
1 |
1 |
Two-hybrid |
PSY2 |
YNL201C |
Subunit of protein phosphatase PP4 complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
ECM11 |
YDR446W |
Meiosis-specific protein |
physical |
1 |
1 |
1 |
Two-hybrid |
ECM11 |
YDR446W |
Meiosis-specific protein |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
MCM3 |
YEL032W |
Protein involved in DNA replication |
physical |
1 |
1 |
1 |
Reconstituted Complex |
MCM3 |
YEL032W |
Protein involved in DNA replication |
genetic |
1 |
1 |
1 |
Negative Genetic |
ISW1 |
YBR245C |
ATPase subunit of imitation-switch (ISWI) class chromatin remodelers |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
MPT5 |
YGL178W |
mRNA-binding protein of the PUF family |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
RPS0A |
YGR214W |
Ribosomal 40S subunit protein S0A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS6A |
YPL090C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS12 |
YOR369C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS17A |
YML024W |
Ribosomal protein 51 (rp51) of the small (40s) subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS18A |
YDR450W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS22A |
YJL190C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL26A |
YLR344W |
Ribosomal 60S subunit protein L26A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL31A |
YDL075W |
Ribosomal 60S subunit protein L31A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SSD1 |
YDR293C |
Translational repressor |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
SSD1 |
YDR293C |
Translational repressor |
genetic |
1 |
1 |
1 |
Positive Genetic |
MEP1 |
YGR121C |
Ammonium permease |
genetic |
1 |
1 |
1 |
Dosage Rescue |
PSP1 |
YDR505C |
Asn and gln rich protein of unknown function |
genetic |
1 |
1 |
1 |
Dosage Rescue |
PSP2 |
YML017W |
Asn rich cytoplasmic protein that contains RGG motifs |
genetic |
1 |
1 |
1 |
Dosage Rescue |
SUM1 |
YDR310C |
Transcriptional repressor that regulates middle-sporulation genes |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
KAR3 |
YPR141C |
Minus-end-directed microtubule motor |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
MMS1 |
YPR164W |
Subunit of E3 ubiquitin ligase complex involved in replication repair |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
RAD50 |
YNL250W |
Subunit of MRX complex with Mre11p and Xrs2p |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
RAD52 |
YML032C |
Protein involved in homologous recombination |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
RTS1 |
YOR014W |
B-type regulatory subunit of protein phosphatase 2A (PP2A) |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
SEM1 |
YDR363W-A |
19S proteasome regulatory particle lid subcomplex component |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
SRS2 |
YJL092W |
DNA helicase and DNA-dependent ATPase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
XRS2 |
YDR369C |
FHA domain-containing component of the Mre11 complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
VPS1 |
YKR001C |
Dynamin-like GTPase required for vacuolar sorting |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
MIH1 |
YMR036C |
Protein tyrosine phosphatase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
IPL1 |
YPL209C |
Aurora kinase of chromosomal passenger complex |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
MEP2 |
YNL142W |
Ammonium permease involved in regulation of pseudohyphal growth |
genetic |
1 |
1 |
1 |
Dosage Rescue |
HHF2 |
YNL030W |
Histone H4 |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
MSA1 |
YOR066W |
Activator of G1-specific transcription factors MBF and SBF |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MSH4 |
YFL003C |
Protein involved in meiotic recombination |
genetic |
1 |
1 |
1 |
Negative Genetic |
YJR011C |
YJR011C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
DBP7 |
YKR024C |
Putative ATP-dependent RNA helicase of the DEAD-box family |
genetic |
1 |
1 |
1 |
Negative Genetic |
UBI4 |
YLL039C |
Ubiquitin |
genetic |
1 |
1 |
1 |
Negative Genetic |
TSA1 |
YML028W |
Thioredoxin peroxidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
YPT7 |
YML001W |
Rab family GTPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MOT3 |
YMR070W |
Transcriptional repressor, activator |
genetic |
1 |
1 |
1 |
Negative Genetic |
PSO2 |
YMR137C |
Nuclease required for DNA single- and double-strand break repair |
genetic |
1 |
1 |
1 |
Negative Genetic |
SRO7 |
YPR032W |
Effector of Rab GTPase Sec4p |
genetic |
1 |
1 |
1 |
Negative Genetic |
SIR4 |
YDR227W |
SIR protein involved in assembly of silent chromatin domains |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
MMS22 |
YLR320W |
Subunit of E3 ubiquitin ligase complex involved in replication repair |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
HPR1 |
YDR138W |
Subunit of THO/TREX complexes |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
SLD2 |
YKL108W |
Single-stranded DNA origin-binding and annealing protein |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
CTK1 |
YKL139W |
Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SPT8 |
YLR055C |
Subunit of the SAGA transcriptional regulatory complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CDC73 |
YLR418C |
Component of the Paf1p complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
HST1 |
YOL068C |
NAD(+)-dependent histone deacetylase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RPH1 |
YER169W |
JmjC domain-containing histone demethylase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RFT1 |
YBL020W |
Membrane protein required for translocation of Man5GlcNac2-PP-Dol |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SAP30 |
YMR263W |
Component of Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SWD3 |
YBR175W |
Essential subunit of the COMPASS (Set1C) complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
HAT1 |
YPL001W |
Catalytic subunit of the Hat1p-Hat2p histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SDC1 |
YDR469W |
Subunit of the COMPASS (Set1C) complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SNF5 |
YBR289W |
Subunit of the SWI/SNF chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
HHT2 |
YNL031C |
Histone H3 |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CLB6 |
YGR109C |
B-type cyclin involved in DNA replication during S phase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
STU1 |
YBL034C |
Microtubule plus-end-tracking non-motor protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
CMD1 |
YBR109C |
Calmodulin |
genetic |
1 |
1 |
1 |
Positive Genetic |
PAB1 |
YER165W |
Poly(A) binding protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
SYF1 |
YDR416W |
Member of the NineTeen Complex (NTC) |
genetic |
1 |
1 |
1 |
Positive Genetic |
DED1 |
YOR204W |
ATP-dependent DEAD-box RNA helicase with strand-annealing activity |
genetic |
1 |
1 |
1 |
Positive Genetic |
SDO1 |
YLR022C |
Guanine nucleotide exchange factor (GEF) for Ria1p |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPL10 |
YLR075W |
Ribosomal 60S subunit protein L10 |
genetic |
1 |
1 |
1 |
Positive Genetic |
DCP2 |
YNL118C |
Catalytic subunit of Dcp1p-Dcp2p decapping enzyme complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
CWC25 |
YNL245C |
Splicing factor required for the first step of pre-mRNA splicing |
genetic |
1 |
1 |
1 |
Positive Genetic |
VPS53 |
YJL029C |
Component of the GARP (Golgi-associated retrograde protein) complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
VMA9 |
YCL005W-A |
Vacuolar H+ ATPase subunit e of the V-ATPase V0 subcomplex |
genetic |
1 |
1 |
1 |
Positive Genetic |
COX15 |
YER141W |
Heme a synthase |
genetic |
1 |
1 |
1 |
Positive Genetic |
SCW10 |
YMR305C |
Cell wall protein with similarity to glucanases |
genetic |
1 |
1 |
1 |
Positive Genetic |
RFC5 |
YBR087W |
Subunit of heteropentameric Replication factor C (RF-C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
KRR1 |
YCL059C |
Nucleolar protein required for rRNA synthesis and ribosomal assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPT2 |
YDL007W |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC9 |
YDL164C |
DNA ligase I found in nucleus and mitochondria |
genetic |
1 |
1 |
1 |
Negative Genetic |
STN1 |
YDR082W |
Telomere end-binding and capping protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
PDS1 |
YDR113C |
Securin |
genetic |
1 |
1 |
1 |
Negative Genetic |
TAF10 |
YDR167W |
Subunit (145 kDa) of TFIID and SAGA complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
GUK1 |
YDR454C |
Guanylate kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PUP3 |
YER094C |
Beta 3 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPN12 |
YFR052W |
Subunit of the 19S regulatory particle of the 26S proteasome lid |
genetic |
1 |
1 |
1 |
Negative Genetic |
CEG1 |
YGL130W |
Guanylyltransferase involved in mRNA 5' capping |
genetic |
1 |
1 |
1 |
Negative Genetic |
ZPR1 |
YGR211W |
Essential protein with two zinc fingers |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERG7 |
YHR072W |
Lanosterol synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERG9 |
YHR190W |
Farnesyl-diphosphate farnesyl transferase (squalene synthase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
NEO1 |
YIL048W |
Phospholipid translocase (flippase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
RFA1 |
YAR007C |
Subunit of heterotrimeric Replication Protein A (RPA) |
genetic |
1 |
1 |
1 |
Negative Genetic |
EXO84 |
YBR102C |
Exocyst subunit with dual roles in exocytosis and spliceosome assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
MCD1 |
YDL003W |
Essential alpha-kleisin subunit of the cohesin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRP9 |
YDL030W |
Subunit of the SF3a splicing factor complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
FAD1 |
YDL045C |
Flavin adenine dinucleotide (FAD) synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
TIM22 |
YDL217C |
Essential core component of mitochondrial TIM22 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPC19 |
YDR201W |
Essential subunit of the Dam1 complex (aka DASH complex) |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPT6 |
YGL048C |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
TAF6 |
YGL112C |
Subunit (60 kDa) of TFIID and SAGA complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
SLD3 |
YGL113W |
Protein involved in the initiation of DNA replication |
genetic |
1 |
1 |
1 |
Negative Genetic |
MOB1 |
YIL106W |
Component of the mitotic exit network |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRI1 |
YIR008C |
Subunit of DNA primase |
genetic |
1 |
1 |
1 |
Negative Genetic |
POL31 |
YJR006W |
Subunit of DNA polymerase delta (polymerase III) |
genetic |
1 |
1 |
1 |
Negative Genetic |
IPA1 |
YJR141W |
Protein implicated in pre-mRNA processing and proteasomal degradation |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRI2 |
YKL045W |
Subunit of DNA primase |
genetic |
1 |
1 |
1 |
Negative Genetic |
GRC3 |
YLL035W |
Polynucleotide kinase present on rDNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERG27 |
YLR100W |
3-keto sterol reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
CFT2 |
YLR115W |
Subunit of the mRNA cleavage and polyadenlylation factor (CPF) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEN1 |
YLR430W |
ATP-dependent 5' to 3' RNA/DNA and DNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRP24 |
YMR268C |
Splicing factor that reanneals snRNPs during spliceosome recycling |
genetic |
1 |
1 |
1 |
Negative Genetic |
CLP1 |
YOR250C |
Component of the cleavage and polyadenylation factor I (CF I) |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRE2 |
YPR103W |
Beta 5 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
SGV1 |
YPR161C |
Cyclin (Bur2p)-dependent protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
LSM8 |
YJR022W |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
FIP1 |
YJR093C |
Subunit of cleavage polyadenylation factor (CPF) |
genetic |
1 |
1 |
1 |
Negative Genetic |
MIF2 |
YKL089W |
Centromeric CDEIII region binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
SRP102 |
YKL154W |
Signal recognition particle (SRP) receptor beta subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
EBP2 |
YKL172W |
Required for 25S rRNA maturation and 60S ribosomal subunit assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
UBA1 |
YKL210W |
Ubiquitin activating enzyme (E1) |
genetic |
1 |
1 |
1 |
Negative Genetic |
LAS1 |
YKR063C |
Endonuclease involved in pre-rRNA processing at both ends of ITS2 |
genetic |
1 |
1 |
1 |
Negative Genetic |
DAD2 |
YKR083C |
Essential subunit of the Dam1 complex (aka DASH complex) |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRP16 |
YKR086W |
DEAH-box RNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
EMG1 |
YLR186W |
Methyltransferase for rRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
POB3 |
YML069W |
Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERO1 |
YML130C |
Thiol oxidase required for oxidative protein folding in the ER |
genetic |
1 |
1 |
1 |
Negative Genetic |
DML1 |
YMR211W |
Essential protein involved in mtDNA inheritance |
genetic |
1 |
1 |
1 |
Negative Genetic |
TAF9 |
YMR236W |
Subunit (17 kDa) of TFIID and SAGA complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
POL1 |
YNL102W |
Catalytic subunit of the DNA polymerase I alpha-primase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
INN1 |
YNL152W |
Essential protein that associates with contractile actomyosin ring |
genetic |
1 |
1 |
1 |
Negative Genetic |
RFC1 |
YOR217W |
Subunit of heteropentameric Replication factor C (RF-C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERG10 |
YPL028W |
Acetyl-CoA C-acetyltransferase (acetoacetyl-CoA thiolase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC62 |
YPL094C |
Essential subunit of Sec63 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
YTH1 |
YPR107C |
Essential RNA-binding component of cleavage and polyadenylation factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
NUT2 |
YPR168W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
DEP1 |
YAL013W |
Component of the Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
YBL081W |
YBL081W |
Non-essential protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
CSG2 |
YBR036C |
Endoplasmic reticulum membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
IMG2 |
YCR071C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
HTA1 |
YDR225W |
Histone H2A |
genetic |
1 |
1 |
1 |
Negative Genetic |
RIM8 |
YGL045W |
Protein involved in proteolytic activation of Rim101p |
genetic |
1 |
1 |
1 |
Negative Genetic |
NNF2 |
YGR089W |
Protein that exhibits physical and genetic interactions with Rpb8p |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPC1 |
YJR010C-A |
Subunit of the signal peptidase complex (SPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
KCH1 |
YJR054W |
Potassium transporter that mediates K+ influx |
genetic |
1 |
1 |
1 |
Negative Genetic |
MDM35 |
YKL053C-A |
Mitochondrial intermembrane space protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
SIW14 |
YNL032W |
Inositol phosphatase involved in inositol pyrophosphate metabolism |
genetic |
1 |
1 |
1 |
Negative Genetic |
STI1 |
YOR027W |
Evolutionarily-conserved Hsp90 cochaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
LGE1 |
YPL055C |
Protein involved in histone H2B ubiquitination |
genetic |
1 |
1 |
1 |
Negative Genetic |
CYS3 |
YAL012W |
Cystathionine gamma-lyase |
genetic |
1 |
1 |
1 |
Negative Genetic |
FUN26 |
YAL022C |
High affinity, broad selectivity, nucleoside/nucleobase transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
PAU8 |
YAL068C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YBL086C |
YBL086C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
CSM1 |
YCR086W |
Nucleolar protein that mediates homolog segregation during meiosis I |
genetic |
1 |
1 |
1 |
Negative Genetic |
RAM1 |
YDL090C |
Beta subunit of the CAAX farnesyltransferase (FTase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
DUN1 |
YDL101C |
Cell-cycle checkpoint S/T protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PHO2 |
YDL106C |
Homeobox transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRX19 |
YDL183C |
Protein that may form an active mitochondrial KHE system |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPT3 |
YDR392W |
Subunit of the SAGA and SAGA-like transcriptional regulatory complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
LRS4 |
YDR439W |
Nucleolar protein that forms a complex with Csm1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
PES4 |
YFR023W |
Poly(A) binding protein, suppressor of DNA polymerase epsilon mutation |
genetic |
1 |
1 |
1 |
Negative Genetic |
SGF73 |
YGL066W |
Subunit of DUBm module of SAGA and SLIK |
genetic |
1 |
1 |
1 |
Negative Genetic |
LIF1 |
YGL090W |
Component of the DNA ligase IV complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SIP2 |
YGL208W |
One of three alternate beta subunits of the Snf1 kinase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RMR1 |
YGL250W |
Protein required for meiotic recombination and gene conversion |
genetic |
1 |
1 |
1 |
Negative Genetic |
RIM101 |
YHL027W |
Cys2His2 zinc-finger transcriptional repressor |
genetic |
1 |
1 |
1 |
Negative Genetic |
RRM3 |
YHR031C |
DNA helicase involved in rDNA replication and Ty1 transposition |
genetic |
1 |
1 |
1 |
Negative Genetic |
RRF1 |
YHR038W |
Mitochondrial ribosome recycling factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
CTF8 |
YHR191C |
Subunit of a complex with Ctf18p |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPN10 |
YHR200W |
Proteasome polyubiquitin receptor |
genetic |
1 |
1 |
1 |
Negative Genetic |
YIL089W |
YIL089W |
Protein of unknown function found in the ER and vacuole lumen |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL40A |
YIL148W |
Ubiquitin-ribosomal 60S subunit protein L40A fusion protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
IRC8 |
YJL051W |
Bud tip localized protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL43B |
YJR094W-A |
Ribosomal 60S subunit protein L43B |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRT4 |
YKL009W |
Protein involved in mRNA turnover and ribosome assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
DEF1 |
YKL054C |
RNAPII degradation factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEG2 |
YKL105C |
Eisosome component |
genetic |
1 |
1 |
1 |
Negative Genetic |
RAD27 |
YKL113C |
5' to 3' exonuclease, 5' flap endonuclease |
genetic |
1 |
1 |
1 |
Negative Genetic |
LMO1 |
YLL007C |
Homolog of mammalian ELMO (Engulfment and celL MOtility) |
genetic |
1 |
1 |
1 |
Negative Genetic |
LDB18 |
YLL049W |
Component of the dynactin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL38 |
YLR325C |
Ribosomal 60S subunit protein L38 |
genetic |
1 |
1 |
1 |
Negative Genetic |
VBA1 |
YMR088C |
Permease of basic amino acids in the vacuolar membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
EPO1 |
YMR124W |
Protein involved in septin-ER tethering |
genetic |
1 |
1 |
1 |
Negative Genetic |
GAT2 |
YMR136W |
Protein containing GATA family zinc finger motifs |
genetic |
1 |
1 |
1 |
Negative Genetic |
MIN3 |
YMR182W-A |
Mitochondrial protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
PET111 |
YMR257C |
Mitochondrial translational activator specific for the COX2 mRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
YMR310C |
YMR310C |
Putative methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
VAC7 |
YNL054W |
Integral vacuolar membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
OCA2 |
YNL056W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
PHO23 |
YNL097C |
Component of the Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
NCS2 |
YNL119W |
Protein required for uridine thiolation of Lys(UUU) and Glu(UUC) tRNAs |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRX7 |
YNL211C |
Protein that associates with mitochondrial ribosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
HCH1 |
YNL281W |
Heat shock protein regulator |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRS5 |
YOL061W |
5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
IMA2 |
YOL157C |
Isomaltase (alpha-1,6-glucosidase/alpha-methylglucosidase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
DNL4 |
YOR005C |
DNA ligase required for nonhomologous end-joining (NHEJ) |
genetic |
1 |
1 |
1 |
Negative Genetic |
MCA1 |
YOR197W |
Ca2+-dependent cysteine protease |
genetic |
1 |
1 |
1 |
Negative Genetic |
PYK2 |
YOR347C |
Pyruvate kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PIP2 |
YOR363C |
Autoregulatory, oleate-activated transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
SNF8 |
YPL002C |
Component of the ESCRT-II complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
MGR2 |
YPL098C |
Subunit of the TIM23 translocase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CTI6 |
YPL181W |
Component of the Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
GLD1 |
YPR109W |
Component of Dsc E3 ligase complex in Golgi and endosomes |
genetic |
1 |
1 |
1 |
Negative Genetic |
YKU80 |
YMR106C |
Subunit of telomeric Ku complex (Yku70p-Yku80p) |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
GCR2 |
YNL199C |
Transcriptional activator of genes involved in glycolysis |
genetic |
1 |
1 |
1 |
Positive Genetic |
SPE2 |
YOL052C |
S-adenosylmethionine decarboxylase |
genetic |
1 |
1 |
1 |
Positive Genetic |
OCT1 |
YKL134C |
Mitochondrial intermediate peptidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
YPK1 |
YKL126W |
S/T protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPE1 |
YKL184W |
Ornithine decarboxylase |
genetic |
1 |
1 |
1 |
Positive Genetic |
FUS3 |
YBL016W |
Mitogen-activated serine/threonine protein kinase involved in mating |
genetic |
1 |
1 |
1 |
Negative Genetic |
IMD4 |
YML056C |
Inosine monophosphate dehydrogenase |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPL11A |
YPR102C |
Ribosomal 60S subunit protein L11A |
genetic |
1 |
1 |
1 |
Negative Genetic |
RTG2 |
YGL252C |
Sensor of mitochondrial dysfunction |
genetic |
1 |
1 |
1 |
Positive Genetic |
ESP1 |
YGR098C |
Separase/separin, a caspase-like cysteine protease |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
HRQ1 |
YDR291W |
3'-5' DNA helicase of the conserved RecQ family |
genetic |
1 |
1 |
1 |
Positive Genetic |
SGS1 |
YMR190C |
RecQ family nucleolar DNA helicase |
genetic |
1 |
1 |
1 |
Positive Genetic |
ABF2 |
YMR072W |
Mitochondrial DNA-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
CCT8 |
YJL008C |
Subunit of the cytosolic chaperonin Cct ring complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
CCT6 |
YDR188W |
Subunit of the cytosolic chaperonin Cct ring complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CAB5 |
YDR196C |
Subunit of the CoA-Synthesizing Protein Complex (CoA-SPC) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BBC1 |
YJL020C |
Protein possibly involved in assembly of actin patches |
physical |
1 |
1 |
1 |
Two-hybrid |
CDC15 |
YAR019C |
Hippo-like kinase of the Mitotic Exit Network |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
BIR1 |
YJR089W |
Subunit of chromosomal passenger complex (CPC) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CDC34 |
YDR054C |
Ubiquitin-conjugating enzyme (E2) |
physical |
1 |
1 |
1 |
Biochemical Activity |
CDC34 |
YDR054C |
Ubiquitin-conjugating enzyme (E2) |
genetic |
1 |
1 |
1 |
Positive Genetic |
APC11 |
YDL008W |
Catalytic core subunit, Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC27 |
YBL084C |
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
BUB1 |
YGR188C |
Protein kinase involved in the cell cycle checkpoint into anaphase |
genetic |
1 |
1 |
1 |
Positive Genetic |
CCZ1 |
YBR131W |
Subunit of a heterodimeric guanine nucleotide exchange factor (GEF) |
genetic |
1 |
1 |
1 |
Positive Genetic |
ABF1 |
YKL112W |
DNA binding protein with possible chromatin-reorganizing activity |
physical |
1 |
1 |
1 |
Reconstituted Complex |
ABF1 |
YKL112W |
DNA binding protein with possible chromatin-reorganizing activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
BET4 |
YJL031C |
Alpha subunit of Type II geranylgeranyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
BTS1 |
YPL069C |
Geranylgeranyl diphosphate synthase (GGPPS) |
genetic |
1 |
1 |
1 |
Positive Genetic |
CAB4 |
YGR277C |
Subunit of the CoA-Synthesizing Protein Complex (CoA-SPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |