TAF6 |
YGL112C |
Subunit (60 kDa) of TFIID and SAGA complexes |
physical |
21 |
6 |
15 |
Two-hybrid, Two-hybrid, Two-hybrid, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-MS, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Co-localization, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-MS, Reconstituted Complex, Reconstituted Complex, Affinity Capture-Western, Co-purification, Co-purification |
TAF5 |
YBR198C |
Subunit (90 kDa) of TFIID and SAGA complexes |
physical |
19 |
5 |
15 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Co-purification, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-localization, Two-hybrid, Affinity Capture-MS, Affinity Capture-MS, Co-purification, Co-purification, Affinity Capture-MS, Co-purification |
SPT7 |
YBR081C |
Subunit of the SAGA transcriptional regulatory complex |
physical |
18 |
3 |
16 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Co-purification, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Co-purification |
TAF1 |
YGR274C |
TFIID subunit, involved in RNA pol II transcription initiation |
physical |
18 |
4 |
15 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-localization, Affinity Capture-Western, Co-purification, Affinity Capture-Western, Co-localization, Affinity Capture-MS, Affinity Capture-MS |
TAF12 |
YDR145W |
Subunit (61/68 kDa) of TFIID and SAGA complexes |
physical |
16 |
5 |
12 |
Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-Western, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-localization, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-purification, Co-purification, Affinity Capture-MS, Co-purification |
SPT20 |
YOL148C |
Subunit of the SAGA transcriptional regulatory complex |
physical |
15 |
4 |
9 |
Affinity Capture-MS, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-purification, Co-purification, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Co-fractionation, Affinity Capture-MS, Co-purification, Co-purification |
TAF10 |
YDR167W |
Subunit (145 kDa) of TFIID and SAGA complexes |
physical |
12 |
4 |
12 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Co-purification, Co-purification, Affinity Capture-MS, Co-localization, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-purification |
GCN5 |
YGR252W |
Catalytic subunit of ADA and SAGA histone acetyltransferase complexes |
physical |
11 |
4 |
8 |
Affinity Capture-MS, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Co-fractionation, Affinity Capture-MS |
HFI1 |
YPL254W |
Adaptor protein required for structural integrity of the SAGA complex |
physical |
10 |
4 |
8 |
Affinity Capture-MS, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-purification, Affinity Capture-MS, Affinity Capture-Western, Co-fractionation, Co-purification |
ADA2 |
YDR448W |
Transcription coactivator |
physical |
10 |
3 |
8 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
NGG1 |
YDR176W |
Subunit of chromatin modifying histone acetyltransferase complexes |
physical |
9 |
4 |
8 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Co-fractionation, Co-purification |
TAF4 |
YMR005W |
TFIID subunit (48 kDa) |
physical |
9 |
3 |
7 |
Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, Affinity Capture-MS, Affinity Capture-MS |
TAF13 |
YML098W |
TFIID subunit (19 kDa) |
physical |
8 |
1 |
7 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
TAF11 |
YML015C |
TFIID subunit (40 kDa) |
physical |
8 |
2 |
6 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western |
SPT15 |
YER148W |
TATA-binding protein (TBP) |
physical |
8 |
3 |
5 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Co-localization, Affinity Capture-MS |
TRA1 |
YHR099W |
Subunit of SAGA and NuA4 histone acetyltransferase complexes |
physical |
7 |
3 |
7 |
Affinity Capture-MS, Affinity Capture-Western, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-purification |
SGF73 |
YGL066W |
Subunit of DUBm module of SAGA and SLIK |
physical |
7 |
2 |
5 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-purification |
SPT8 |
YLR055C |
Subunit of the SAGA transcriptional regulatory complex |
physical |
6 |
2 |
5 |
Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
UBP8 |
YMR223W |
Ubiquitin-specific protease component of the SAGA acetylation complex |
physical |
6 |
2 |
5 |
Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
SWC5 |
YBR231C |
Component of the SWR1 complex |
genetic |
6 |
4 |
4 |
Negative Genetic, Phenotypic Enhancement, Positive Genetic, Synthetic Lethality, Synthetic Lethality, Positive Genetic |
TAF3 |
YPL011C |
TFIID subunit (47 kDa) |
physical |
6 |
1 |
4 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
SPT3 |
YDR392W |
Subunit of the SAGA and SAGA-like transcriptional regulatory complexes |
physical |
5 |
2 |
5 |
Affinity Capture-MS, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Co-purification |
TAF2 |
YCR042C |
TFIID subunit (150 kDa) |
physical |
5 |
2 |
4 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS |
ARP6 |
YLR085C |
Actin-related protein that binds nucleosomes |
genetic |
5 |
2 |
4 |
Negative Genetic, Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic |
VPS71 |
YML041C |
Nucleosome-binding component of the SWR1 complex |
genetic |
5 |
2 |
4 |
Negative Genetic, Negative Genetic, Synthetic Lethality, Synthetic Lethality, Negative Genetic |
TAF7 |
YMR227C |
TFIID subunit (67 kDa) |
physical |
5 |
1 |
4 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
SGF11 |
YPL047W |
Integral subunit of SAGA histone acetyltransferase complex |
physical |
5 |
1 |
4 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
SGF29 |
YCL010C |
Component of the HAT/Core module of the SAGA, SLIK, and ADA complexes |
physical |
5 |
3 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Co-fractionation |
SWR1 |
YDR334W |
Swi2/Snf2-related ATPase |
genetic |
5 |
3 |
3 |
Negative Genetic, Synthetic Lethality, Synthetic Lethality, Phenotypic Enhancement, Negative Genetic |
SGF73 |
YGL066W |
Subunit of DUBm module of SAGA and SLIK |
genetic |
5 |
2 |
3 |
Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic |
TAF6 |
YGL112C |
Subunit (60 kDa) of TFIID and SAGA complexes |
genetic |
5 |
2 |
3 |
Dosage Rescue, Dosage Rescue, Negative Genetic, Negative Genetic, Dosage Rescue |
GCN4 |
YEL009C |
bZIP transcriptional activator of amino acid biosynthetic genes |
physical |
4 |
2 |
4 |
Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex |
TAF8 |
YML114C |
TFIID subunit (65 kDa) |
physical |
4 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
TAF12 |
YDR145W |
Subunit (61/68 kDa) of TFIID and SAGA complexes |
genetic |
4 |
3 |
2 |
Dosage Rescue, Synthetic Lethality, Negative Genetic, Negative Genetic |
PUF3 |
YLL013C |
Protein of the mitochondrial outer surface |
physical |
3 |
1 |
3 |
Affinity Capture-RNA, Affinity Capture-RNA, Affinity Capture-RNA |
HST3 |
YOR025W |
Sirtuin, histone H3 deacetylase |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
VPS72 |
YDR485C |
Htz1p-binding component of the SWR1 complex |
genetic |
3 |
3 |
2 |
Negative Genetic, Phenotypic Enhancement, Synthetic Lethality |
LSM1 |
YJL124C |
Lsm (Like Sm) protein |
genetic |
3 |
2 |
2 |
Synthetic Lethality, Synthetic Lethality, Negative Genetic |
HCR1 |
YLR192C |
eIF3j component of translation initiation factor 3 (eIF3) |
genetic |
3 |
2 |
2 |
Synthetic Lethality, Synthetic Lethality, Positive Genetic |
ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
genetic |
3 |
2 |
2 |
Synthetic Haploinsufficiency, Synthetic Haploinsufficiency, Negative Genetic |
BEM1 |
YBR200W |
Protein containing SH3-domains |
genetic |
3 |
2 |
2 |
Positive Genetic, Synthetic Lethality, Synthetic Lethality |
MED1 |
YPR070W |
Subunit of the RNA polymerase II mediator complex |
genetic |
3 |
2 |
2 |
Negative Genetic, Synthetic Lethality, Synthetic Lethality |
FYV4 |
YHR059W |
Protein of unknown function |
genetic |
3 |
2 |
2 |
Negative Genetic, Synthetic Lethality, Synthetic Lethality |
HTZ1 |
YOL012C |
Histone variant H2AZ |
genetic |
3 |
2 |
2 |
Negative Genetic, Synthetic Lethality, Synthetic Lethality |
SDS3 |
YIL084C |
Component of the Rpd3L histone deacetylase complex |
genetic |
3 |
2 |
2 |
Synthetic Lethality, Synthetic Lethality, Negative Genetic |
SIN3 |
YOL004W |
Component of both the Rpd3S and Rpd3L histone deacetylase complexes |
genetic |
3 |
2 |
2 |
Negative Genetic, Synthetic Lethality, Synthetic Lethality |
SNF2 |
YOR290C |
Catalytic subunit of the SWI/SNF chromatin remodeling complex |
genetic |
3 |
2 |
2 |
Synthetic Lethality, Synthetic Lethality, Negative Genetic |
SPT8 |
YLR055C |
Subunit of the SAGA transcriptional regulatory complex |
genetic |
3 |
2 |
2 |
Synthetic Lethality, Synthetic Lethality, Negative Genetic |
TAF5 |
YBR198C |
Subunit (90 kDa) of TFIID and SAGA complexes |
genetic |
3 |
2 |
2 |
Dosage Rescue, Negative Genetic, Negative Genetic |
GCR2 |
YNL199C |
Transcriptional activator of genes involved in glycolysis |
genetic |
3 |
2 |
2 |
Negative Genetic, Synthetic Lethality, Synthetic Lethality |
CDC7 |
YDL017W |
S/T kinase and catalytic subunit of DDK (Dbf4-dependent kinase) |
genetic |
3 |
2 |
2 |
Synthetic Lethality, Negative Genetic, Negative Genetic |
AIM4 |
YBR194W |
Protein proposed to be associated with the nuclear pore complex |
genetic |
3 |
2 |
2 |
Synthetic Lethality, Synthetic Lethality, Negative Genetic |
SPT3 |
YDR392W |
Subunit of the SAGA and SAGA-like transcriptional regulatory complexes |
genetic |
3 |
2 |
2 |
Synthetic Lethality, Synthetic Lethality, Negative Genetic |
THP3 |
YPR045C |
Protein that may have a role in transcription elongation |
genetic |
3 |
2 |
2 |
Synthetic Lethality, Synthetic Lethality, Negative Genetic |
SPT21 |
YMR179W |
Protein with a role in transcriptional silencing |
genetic |
3 |
2 |
2 |
Negative Genetic, Synthetic Lethality, Synthetic Lethality |
TAF14 |
YPL129W |
Subunit of TFIID, TFIIF, INO80, SWI/SNF, and NuA3 complexes |
physical |
3 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
SUS1 |
YBR111W-A |
Global transcriptional regulator, component of SAGA, TREX-2 complexes |
physical |
3 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
SWI6 |
YLR182W |
Transcription cofactor |
genetic |
3 |
1 |
2 |
Synthetic Lethality, Synthetic Lethality, Synthetic Lethality |
SRB2 |
YHR041C |
Subunit of the RNA polymerase II mediator complex |
genetic |
2 |
2 |
2 |
Phenotypic Enhancement, Negative Genetic |
TAF4 |
YMR005W |
TFIID subunit (48 kDa) |
genetic |
2 |
2 |
2 |
Dosage Rescue, Negative Genetic |
GIS2 |
YNL255C |
Translational activator for mRNAs with internal ribosome entry sites |
physical |
2 |
2 |
2 |
Affinity Capture-MS, Affinity Capture-RNA |
CKB2 |
YOR039W |
Beta' regulatory subunit of casein kinase 2 (CK2) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PAT1 |
YCR077C |
Deadenylation-dependent mRNA-decapping factor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RRP6 |
YOR001W |
Nuclear exosome exonuclease component |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
EAF3 |
YPR023C |
Component of the Rpd3S histone deacetylase complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
BLM10 |
YFL007W |
Proteasome activator |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
INO4 |
YOL108C |
Transcription factor involved in phospholipid synthesis |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
PYC2 |
YBR218C |
Pyruvate carboxylase isoform |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
OM45 |
YIL136W |
Mitochondrial outer membrane protein of unknown function |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
ULS1 |
YOR191W |
Swi2/Snf2-related translocase, SUMO-Targeted Ubiquitin Ligase (STUbL) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
VAM3 |
YOR106W |
Syntaxin-like vacuolar t-SNARE |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
YCR090C |
YCR090C |
Putative protein of unknown function |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
YLR287C |
YLR287C |
Putative protein of unknown function |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
YOL162W |
YOL162W |
Putative protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
EXO1 |
YOR033C |
5'-3' exonuclease and flap-endonuclease |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SEC22 |
YLR268W |
R-SNARE protein |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
NMD2 |
YHR077C |
Protein involved in the nonsense-mediated mRNA decay (NMD) pathway |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
HSP26 |
YBR072W |
Small heat shock protein (sHSP) with chaperone activity |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
EHT1 |
YBR177C |
Octanoyl-CoA:ethanol acyltransferase |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
LYS20 |
YDL182W |
Homocitrate synthase isozyme and functions in DNA repair |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RPL8B |
YLL045C |
Ribosomal 60S subunit protein L8A |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
SLM3 |
YDL033C |
tRNA-specific 2-thiouridylase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
NTG2 |
YOL043C |
DNA N-glycosylase and apurinic/apyrimidinic (AP) lyase |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
SHE1 |
YBL031W |
Mitotic spindle protein |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
PRY1 |
YJL079C |
Lipid binding protein |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
LGE1 |
YPL055C |
Protein involved in histone H2B ubiquitination |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RPL21B |
YPL079W |
Ribosomal 60S subunit protein L21B |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
RTC2 |
YBR147W |
Putative vacuolar membrane transporter for cationic amino acids |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
PAF1 |
YBR279W |
Component of the Paf1p complex involved in transcription elongation |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
IKI3 |
YLR384C |
Subunit of Elongator complex |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
RPL27A |
YHR010W |
Ribosomal 60S subunit protein L27A |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
MDM20 |
YOL076W |
Non-catalytic subunit of the NatB N-terminal acetyltransferase |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
SIT4 |
YDL047W |
Ceramide-activated, type 2A-related serine-threonine phosphatase |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
NPL3 |
YDR432W |
RNA-binding protein |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
RPB4 |
YJL140W |
RNA polymerase II subunit B32 |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
RSC2 |
YLR357W |
Component of the RSC chromatin remodeling complex |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
SRB5 |
YGR104C |
Subunit of the RNA polymerase II mediator complex |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
RPN11 |
YFR004W |
Metalloprotease subunit of 19S regulatory particle |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
RPN6 |
YDL097C |
Essential, non-ATPase regulatory subunit of the 26S proteasome lid |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
ASF1 |
YJL115W |
Nucleosome assembly factor |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
BDF1 |
YLR399C |
BET family transcriptional regulator |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
CTK1 |
YKL139W |
Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
GCN3 |
YKR026C |
Alpha subunit of translation initiation factor eIF2B |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
CSE2 |
YNR010W |
Subunit of the RNA polymerase II mediator complex |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
ADA2 |
YDR448W |
Transcription coactivator |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
MRPL10 |
YNL284C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
MRP20 |
YDR405W |
Mitochondrial ribosomal protein of the large subunit |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
IES5 |
YER092W |
Non-essential INO80 chromatin remodeling complex subunit |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
DOA4 |
YDR069C |
Ubiquitin hydrolase |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
PEP3 |
YLR148W |
Component of CORVET membrane tethering complex |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
MET18 |
YIL128W |
Component of cytosolic iron-sulfur protein assembly (CIA) machinery |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
REF2 |
YDR195W |
RNA-binding protein |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
MRPL6 |
YHR147C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
IWR1 |
YDL115C |
RNA polymerase II transport factor, conserved from yeast to humans |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
RPB9 |
YGL070C |
RNA polymerase II subunit B12.6 |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
RPD3 |
YNL330C |
Histone deacetylase, component of both the Rpd3S and Rpd3L complexes |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
MNN10 |
YDR245W |
Subunit of a Golgi mannosyltransferase complex |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
SNF5 |
YBR289W |
Subunit of the SWI/SNF chromatin remodeling complex |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
GCN5 |
YGR252W |
Catalytic subunit of ADA and SAGA histone acetyltransferase complexes |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
HFI1 |
YPL254W |
Adaptor protein required for structural integrity of the SAGA complex |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
NGG1 |
YDR176W |
Subunit of chromatin modifying histone acetyltransferase complexes |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
SPT7 |
YBR081C |
Subunit of the SAGA transcriptional regulatory complex |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
SRB8 |
YCR081W |
Subunit of the RNA polymerase II mediator complex |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
TAF1 |
YGR274C |
TFIID subunit, involved in RNA pol II transcription initiation |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
TAF13 |
YML098W |
TFIID subunit (19 kDa) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
BCK1 |
YJL095W |
MAPKKK acting in the protein kinase C signaling pathway |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
SDC1 |
YDR469W |
Subunit of the COMPASS (Set1C) complex |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
DSS1 |
YMR287C |
3'-5' exoribonuclease |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
RAD6 |
YGL058W |
Ubiquitin-conjugating enzyme (E2) |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
SLT2 |
YHR030C |
Serine/threonine MAP kinase |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
BEM4 |
YPL161C |
Protein involved in establishment of cell polarity and bud emergence |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
SSN8 |
YNL025C |
Cyclin-like component of RNA polymerase II holoenzyme |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
CTK3 |
YML112W |
Gamma subunit of C-terminal domain kinase I |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
IBA57 |
YJR122W |
Protein involved in incorporating iron-sulfur clusters into proteins |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
MOB2 |
YFL034C-B |
Activator of Cbk1p kinase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
MSN5 |
YDR335W |
Karyopherin |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
RPS24A |
YER074W |
Protein component of the small (40S) ribosomal subunit |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
RSC1 |
YGR056W |
Component of the RSC chromatin remodeling complex |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
TAF8 |
YML114C |
TFIID subunit (65 kDa) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
TUF1 |
YOR187W |
Mitochondrial translation elongation factor Tu (EF-Tu) |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
VPS3 |
YDR495C |
Component of CORVET membrane tethering complex |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
VMA11 |
YPL234C |
Vacuolar ATPase V0 domain subunit c' |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
VMA10 |
YHR039C-A |
Subunit G of the V1 peripheral membrane domain of V-ATPase |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
VAN1 |
YML115C |
Component of the mannan polymerase I |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
VAC14 |
YLR386W |
Enzyme regulator |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
VRP1 |
YLR337C |
Verprolin, proline-rich actin-associated protein |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
YAR1 |
YPL239W |
Nucleocytoplasmic shuttling assembly chaperone |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
YNG1 |
YOR064C |
Subunit of the NuA3 histone acetyltransferase complex |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
ZAP1 |
YJL056C |
Zinc-regulated transcription factor |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
YAF9 |
YNL107W |
Subunit of NuA4 histone H4 acetyltransferase and SWR1 complexes |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
SWI3 |
YJL176C |
Subunit of the SWI/SNF chromatin remodeling complex |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
BUB1 |
YGR188C |
Protein kinase involved in the cell cycle checkpoint into anaphase |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
MOT2 |
YER068W |
Ubiquitin-protein ligase subunit of the CCR4-NOT complex |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
CTK2 |
YJL006C |
Beta subunit of C-terminal domain kinase I (CTDK-I) |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
DBF4 |
YDR052C |
Regulatory subunit of Cdc7p-Dbf4p kinase complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
SSN3 |
YPL042C |
Component of the RNA polymerase II mediator complex |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
STE20 |
YHL007C |
Cdc42p-activated signal transducing kinase |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
SSN2 |
YDR443C |
Subunit of the RNA polymerase II mediator complex |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
SRM1 |
YGL097W |
Nucleotide exchange factor for Gsp1p |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
SPT10 |
YJL127C |
Histone H3 acetylase with a role in transcriptional regulation |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
CLA4 |
YNL298W |
Cdc42p-activated signal transducing kinase |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
NUP188 |
YML103C |
Subunit of the inner ring of the nuclear pore complex (NPC) |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
MET1 |
YKR069W |
S-adenosyl-L-methionine uroporphyrinogen III transmethylase |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
MOG1 |
YJR074W |
Conserved nuclear protein that interacts with GTP-Gsp1p |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
RPS18A |
YDR450W |
Protein component of the small (40S) ribosomal subunit |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
RMI1 |
YPL024W |
Subunit of the RecQ (Sgs1p) - Topo III (Top3p) complex |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
RPS10B |
YMR230W |
Protein component of the small (40S) ribosomal subunit |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
RIM21 |
YNL294C |
pH sensor molecule, component of the RIM101 pathway |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
SAS5 |
YOR213C |
Subunit of the SAS complex (Sas2p, Sas4p, Sas5p) |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
RPS6A |
YPL090C |
Protein component of the small (40S) ribosomal subunit |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
KRE28 |
YDR532C |
Subunit of a kinetochore-microtubule binding complex |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
LDB19 |
YOR322C |
Alpha-arrestin, Ub-ligase adaptor for Rsp5p |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
RPS10A |
YOR293W |
Protein component of the small (40S) ribosomal subunit |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
FYV6 |
YNL133C |
Protein of unknown function |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
RPS19B |
YNL302C |
Protein component of the small (40S) ribosomal subunit |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
RPS27B |
YHR021C |
Protein component of the small (40S) ribosomal subunit |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
RIM13 |
YMR154C |
Calpain-like cysteine protease |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
SHE4 |
YOR035C |
Protein containing a UCS (UNC-45/CRO1/SHE4) domain |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
ILM1 |
YJR118C |
Protein of unknown function |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
CDC1 |
YDR182W |
Putative mannose-ethanolamine phosphate phosphodiesterase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
FSH2 |
YMR222C |
Putative serine hydrolase that localizes to the cytoplasm |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
YAP6 |
YDR259C |
Basic leucine zipper (bZIP) transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
UME1 |
YPL139C |
Component of both the Rpd3S and Rpd3L histone deacetylase complexes |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
CDC73 |
YLR418C |
Component of the Paf1p complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
CHD1 |
YER164W |
Chromatin remodeler that regulates various aspects of transcription |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DSN1 |
YIR010W |
Essential component of the outer kinetochore MIND complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPO21 |
YDL140C |
RNA polymerase II largest subunit B220 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
POB3 |
YML069W |
Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) |
genetic |
1 |
1 |
1 |
Positive Genetic |
RTF1 |
YGL244W |
Subunit of RNAPII-associated chromatin remodeling Paf1 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPB2 |
YOR151C |
RNA polymerase II second largest subunit B150 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
IKI3 |
YLR384C |
Subunit of Elongator complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
EAF1 |
YDR359C |
Component of the NuA4 histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
HSP60 |
YLR259C |
Tetradecameric mitochondrial chaperonin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL30 |
YGL030W |
Ribosomal 60S subunit protein L30 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RRP1 |
YDR087C |
Essential evolutionarily conserved nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
SSF1 |
YHR066W |
Constituent of 66S pre-ribosomal particles |
genetic |
1 |
1 |
1 |
Positive Genetic |
PFK27 |
YOL136C |
6-phosphofructo-2-kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
POP1 |
YNL221C |
Subunit of RNase MRP, nuclear RNase P and telomerase complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SMX3 |
YPR182W |
Core Sm protein Sm F |
genetic |
1 |
1 |
1 |
Positive Genetic |
SNU114 |
YKL173W |
GTPase component of U5 snRNP involved in mRNA splicing via spliceosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
BRE1 |
YDL074C |
E3 ubiquitin ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
NOP56 |
YLR197W |
Essential evolutionarily-conserved nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
CSL4 |
YNL232W |
Exosome non-catalytic core component |
genetic |
1 |
1 |
1 |
Positive Genetic |
RRP42 |
YDL111C |
Exosome non-catalytic core component |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPC34 |
YNR003C |
RNA polymerase III subunit C34 |
genetic |
1 |
1 |
1 |
Positive Genetic |
GCD11 |
YER025W |
Gamma subunit of the translation initiation factor eIF2 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ARP7 |
YPR034W |
Component of both the SWI/SNF and RSC chromatin remodeling complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARP9 |
YMR033W |
Component of both the SWI/SNF and RSC chromatin remodeling complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
RSC4 |
YKR008W |
Component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RSC8 |
YFR037C |
Component of the RSC chromatin remodeling complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RSC8 |
YFR037C |
Component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
MED7 |
YOL135C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SRB4 |
YER022W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
PWP1 |
YLR196W |
Protein with WD-40 repeats involved in rRNA processing |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPN5 |
YDL147W |
Subunit of the CSN and 26S proteasome lid complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPT6 |
YGL048C |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPT3 |
YDR394W |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
SRP1 |
YNL189W |
Karyopherin alpha homolog |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CFT2 |
YLR115W |
Subunit of the mRNA cleavage and polyadenlylation factor (CPF) |
genetic |
1 |
1 |
1 |
Positive Genetic |
SSD1 |
YDR293C |
Translational repressor |
genetic |
1 |
1 |
1 |
Negative Genetic |
CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
NAB2 |
YGL122C |
Nuclear polyadenylated RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
ACC1 |
YNR016C |
Acetyl-CoA carboxylase, biotin containing enzyme |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
APC1 |
YNL172W |
Largest subunit of the Anaphase-Promoting Complex/Cyclosome |
physical |
1 |
1 |
1 |
Two-hybrid |
ASF1 |
YJL115W |
Nucleosome assembly factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CCA1 |
YER168C |
ATP (CTP):tRNA-specific tRNA nucleotidyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
CCL1 |
YPR025C |
Cyclin partner of the cyclin-dependent kinase (CDK) Kin28p |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC14 |
YFR028C |
Protein phosphatase required for mitotic exit |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC24 |
YAL041W |
Guanine nucleotide exchange factor (GEF) for Cdc42p |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC28 |
YBR160W |
Cyclin-dependent kinase (CDK) catalytic subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
CDC11 |
YJR076C |
Component of the septin ring that is required for cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC3 |
YLR314C |
Component of the septin ring that is required for cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
CHC1 |
YGL206C |
Clathrin heavy chain |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CKS1 |
YBR135W |
Cyclin-dependent protein kinase regulatory subunit and adaptor |
genetic |
1 |
1 |
1 |
Negative Genetic |
CLP1 |
YOR250C |
Component of the cleavage and polyadenylation factor I (CF I) |
genetic |
1 |
1 |
1 |
Positive Genetic |
DCP2 |
YNL118C |
Catalytic subunit of Dcp1p-Dcp2p decapping enzyme complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
DNA2 |
YHR164C |
ATP-dependent 5'-flap endonuclease and DNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
DOA1 |
YKL213C |
WD-repeat protein involved in ubiquitin-mediated protein degradation |
genetic |
1 |
1 |
1 |
Negative Genetic |
ELP2 |
YGR200C |
Subunit of Elongator complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
FIP1 |
YJR093C |
Subunit of cleavage polyadenylation factor (CPF) |
genetic |
1 |
1 |
1 |
Negative Genetic |
GGA2 |
YHR108W |
Protein that regulates Arf1p, Arf2p to facilitate Golgi trafficking |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HAT2 |
YEL056W |
Subunit of the Hat1p-Hat2p histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
BDF2 |
YDL070W |
Protein involved in transcription initiation |
genetic |
1 |
1 |
1 |
Negative Genetic |
DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
IPP1 |
YBR011C |
Cytoplasmic inorganic pyrophosphatase (PPase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
CLU1 |
YMR012W |
Subunit of the eukaryotic translation initiation factor 3 (eIF3) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
KEL1 |
YHR158C |
Protein required for proper cell fusion and cell morphology |
genetic |
1 |
1 |
1 |
Positive Genetic |
MCD1 |
YDL003W |
Essential alpha-kleisin subunit of the cohesin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
MCM5 |
YLR274W |
Component of the Mcm2-7 hexameric helicase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
MCM6 |
YGL201C |
Protein involved in DNA replication |
genetic |
1 |
1 |
1 |
Negative Genetic |
GAL11 |
YOL051W |
Subunit of the RNA polymerase II mediator complex |
physical |
1 |
1 |
1 |
PCA |
COG3 |
YER157W |
Essential component of the conserved oligomeric Golgi complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
FBA1 |
YKL060C |
Fructose 1,6-bisphosphate aldolase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MOT1 |
YPL082C |
Essential protein involved in regulation of transcription |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
HSC82 |
YMR186W |
Cytoplasmic chaperone of the Hsp90 family |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CMR1 |
YDL156W |
Nuclear protein with role in transcription, protein quality control |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HTZ1 |
YOL012C |
Histone variant H2AZ |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ITC1 |
YGL133W |
Subunit of ATP-dependent Isw2p-Itc1p chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
NPL4 |
YBR170C |
Substrate-recruiting cofactor of the Cdc48p-Npl4p-Ufd1p segregase |
genetic |
1 |
1 |
1 |
Negative Genetic |
POL1 |
YNL102W |
Catalytic subunit of the DNA polymerase I alpha-primase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
POL12 |
YBL035C |
B subunit of DNA polymerase alpha-primase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
POP7 |
YBR167C |
Subunit of RNase MRP, nuclear RNase P and telomerase |
genetic |
1 |
1 |
1 |
Positive Genetic |
LEA1 |
YPL213W |
Component of U2 snRNP complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
NAB3 |
YPL190C |
RNA-binding protein, subunit of Nrd1 complex (Nrd1p-Nab3p-Sen1p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
RET2 |
YFR051C |
Delta subunit of the coatomer complex (COPI) |
genetic |
1 |
1 |
1 |
Positive Genetic |
RFC5 |
YBR087W |
Subunit of heteropentameric Replication factor C (RF-C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
RCO1 |
YMR075W |
Essential component of the Rpd3S histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CTI6 |
YPL181W |
Component of the Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL2A |
YFR031C-A |
Ribosomal 60S subunit protein L2A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CDC6 |
YJL194W |
Essential ATP-binding protein required for DNA replication |
genetic |
1 |
1 |
1 |
Negative Genetic |
PCI8 |
YIL071C |
Possible shared subunit of Cop9 signalosome (CSN) and eIF3 |
genetic |
1 |
1 |
1 |
Negative Genetic |
NUM1 |
YDR150W |
Protein required for nuclear migration |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PIL1 |
YGR086C |
Eisosome core component |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SEC27 |
YGL137W |
Essential beta'-coat protein of the COPI coatomer |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SEC27 |
YGL137W |
Essential beta'-coat protein of the COPI coatomer |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPP2B |
YDR382W |
Ribosomal protein P2 beta |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SEC66 |
YBR171W |
Non-essential subunit of Sec63 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SET2 |
YJL168C |
Histone methyltransferase with a role in transcriptional elongation |
genetic |
1 |
1 |
1 |
Negative Genetic |
SAP30 |
YMR263W |
Component of Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRP18 |
YGR006W |
Splicing factor and component of snRNP U5 |
genetic |
1 |
1 |
1 |
Negative Genetic |
CCT8 |
YJL008C |
Subunit of the cytosolic chaperonin Cct ring complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SMC3 |
YJL074C |
Subunit of the multiprotein cohesin complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
PRP9 |
YDL030W |
Subunit of the SF3a splicing factor complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
SMD2 |
YLR275W |
Core Sm protein Sm D2 |
genetic |
1 |
1 |
1 |
Positive Genetic |
SNF5 |
YBR289W |
Subunit of the SWI/SNF chromatin remodeling complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPT5 |
YOR117W |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
SRO9 |
YCL037C |
Cytoplasmic RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
SRO9 |
YCL037C |
Cytoplasmic RNA-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
SSL1 |
YLR005W |
Subunit of the core form of RNA polymerase transcription factor TFIIH |
genetic |
1 |
1 |
1 |
Negative Genetic |
SGV1 |
YPR161C |
Cyclin (Bur2p)-dependent protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SUA7 |
YPR086W |
Transcription factor TFIIB |
genetic |
1 |
1 |
1 |
Negative Genetic |
TAF10 |
YDR167W |
Subunit (145 kDa) of TFIID and SAGA complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
TAF11 |
YML015C |
TFIID subunit (40 kDa) |
genetic |
1 |
1 |
1 |
Negative Genetic |
TAF3 |
YPL011C |
TFIID subunit (47 kDa) |
genetic |
1 |
1 |
1 |
Negative Genetic |
CCT6 |
YDR188W |
Subunit of the cytosolic chaperonin Cct ring complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
MGA2 |
YIR033W |
ER membrane protein involved in regulation of OLE1 transcription |
genetic |
1 |
1 |
1 |
Negative Genetic |
GLN1 |
YPR035W |
Glutamine synthetase (GS) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BRE2 |
YLR015W |
Subunit of COMPASS (Set1C) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SWD1 |
YAR003W |
Subunit of the COMPASS (Set1C) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SNT1 |
YCR033W |
Set3C histone deacetylase scaffold |
genetic |
1 |
1 |
1 |
Positive Genetic |
CDC13 |
YDL220C |
Single stranded DNA-binding protein found at TG1-3 telomere G-tails |
genetic |
1 |
1 |
1 |
Negative Genetic |
ASA1 |
YPR085C |
Subunit of the ASTRA complex, involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Positive Genetic |
DMA2 |
YNL116W |
Ubiquitin-protein ligase (E3) |
genetic |
1 |
1 |
1 |
Negative Genetic |
RAD54 |
YGL163C |
DNA-dependent ATPase that stimulates strand exchange |
genetic |
1 |
1 |
1 |
Negative Genetic |
GSP1 |
YLR293C |
Ran GTPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
FAA4 |
YMR246W |
Long chain fatty acyl-CoA synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BUD13 |
YGL174W |
Subunit of the RES complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
GET1 |
YGL020C |
Subunit of the GET complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
SEC53 |
YFL045C |
Phosphomannomutase |
genetic |
1 |
1 |
1 |
Negative Genetic |
GYP6 |
YJL044C |
GTPase-activating protein (GAP) for yeast Rab family member Ypt6p |
genetic |
1 |
1 |
1 |
Negative Genetic |
CCT5 |
YJR064W |
Subunit of the cytosolic chaperonin Cct ring complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SUI2 |
YJR007W |
Alpha subunit of the translation initiation factor eIF2 |
genetic |
1 |
1 |
1 |
Positive Genetic |
ERG27 |
YLR100W |
3-keto sterol reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MLH3 |
YPL164C |
Protein involved in DNA mismatch repair and meiotic recombination |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CDC20 |
YGL116W |
Activator of anaphase-promoting complex/cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Positive Genetic |
SMC6 |
YLR383W |
Subunit of the SMC5-SMC6 complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SGS1 |
YMR190C |
RecQ family nucleolar DNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
BUL1 |
YMR275C |
Alpha-arrestin, component of the Rsp5p E3-ubiquitin ligase complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
IPA1 |
YJR141W |
Protein implicated in pre-mRNA processing and proteasomal degradation |
genetic |
1 |
1 |
1 |
Positive Genetic |
CDC37 |
YDR168W |
Essential Hsp90p co-chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
RNA1 |
YMR235C |
GTPase activating protein (GAP) for Gsp1p |
genetic |
1 |
1 |
1 |
Dosage Rescue |
NTF2 |
YER009W |
Nuclear envelope protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPP0 |
YLR340W |
Conserved ribosomal protein P0 of the ribosomal stalk |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HIR1 |
YBL008W |
Subunit of the HIR complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
CDC15 |
YAR019C |
Hippo-like kinase of the Mitotic Exit Network |
genetic |
1 |
1 |
1 |
Negative Genetic |
ISU1 |
YPL135W |
Conserved protein of the mitochondrial matrix |
genetic |
1 |
1 |
1 |
Negative Genetic |
HHT1 |
YBR010W |
Histone H3 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BOP2 |
YLR267W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
SGT1 |
YOR057W |
Cochaperone protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
LHS1 |
YKL073W |
Molecular chaperone of the endoplasmic reticulum lumen |
genetic |
1 |
1 |
1 |
Negative Genetic |
NOP53 |
YPL146C |
Nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
RTT103 |
YDR289C |
Protein involved in transcription termination by RNA polymerase II |
genetic |
1 |
1 |
1 |
Negative Genetic |
HAP3 |
YBL021C |
Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ELG1 |
YOR144C |
Subunit of an alternative replication factor C complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPT2 |
YER161C |
Protein involved in negative regulation of transcription |
genetic |
1 |
1 |
1 |
Negative Genetic |
MCK1 |
YNL307C |
Dual-specificity ser/thr and tyrosine protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MAS2 |
YHR024C |
Alpha subunit of the mitochondrial processing protease (MPP) |
genetic |
1 |
1 |
1 |
Negative Genetic |
BUB3 |
YOR026W |
Kinetochore checkpoint WD40 repeat protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
MEC3 |
YLR288C |
DNA damage and meiotic pachytene checkpoint protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
ERG11 |
YHR007C |
Lanosterol 14-alpha-demethylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RNH203 |
YLR154C |
Ribonuclease H2 subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
BIT2 |
YBR270C |
Subunit of TORC2 membrane-associated complex |
physical |
1 |
1 |
1 |
Two-hybrid |
ADE2 |
YOR128C |
Phosphoribosylaminoimidazole carboxylase |
physical |
1 |
1 |
1 |
Two-hybrid |
CIT2 |
YCR005C |
Citrate synthase, peroxisomal isozyme involved in glyoxylate cycle |
genetic |
1 |
1 |
1 |
Negative Genetic |
IPK1 |
YDR315C |
Inositol 1,3,4,5,6-pentakisphosphate 2-kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MAD3 |
YJL013C |
Subunit of spindle-assembly checkpoint complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
NUP57 |
YGR119C |
FG-nucleoporin component of central core of the nuclear pore complex |
physical |
1 |
1 |
1 |
Two-hybrid |
RRN6 |
YBL014C |
Component of the core factor (CF) rDNA transcription factor complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ELP6 |
YMR312W |
Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SMC5 |
YOL034W |
Subunit of the SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
BOS1 |
YLR078C |
v-SNARE (vesicle specific SNAP receptor) |
genetic |
1 |
1 |
1 |
Positive Genetic |
APC5 |
YOR249C |
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Positive Genetic |
APC11 |
YDL008W |
Catalytic core subunit, Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
ELP3 |
YPL086C |
Subunit of Elongator complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ELP4 |
YPL101W |
Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
IKI1 |
YHR187W |
Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HTL1 |
YCR020W-B |
Component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS13 |
YDR064W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BRE5 |
YNR051C |
Ubiquitin protease cofactor |
genetic |
1 |
1 |
1 |
Positive Genetic |
SAC3 |
YDR159W |
mRNA export factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SAC3 |
YDR159W |
mRNA export factor |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
RPP1 |
YHR062C |
Subunit of both RNase MRP and nuclear RNase P |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SKO1 |
YNL167C |
Basic leucine zipper transcription factor of the ATF/CREB family |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
WHI3 |
YNL197C |
RNA binding protein that modulates mRNA stability |
physical |
1 |
1 |
1 |
Protein-RNA |
YLR157C-B |
YLR157C-B |
Retrotransposon TYA Gag and TYB Pol genes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
UBA2 |
YDR390C |
Subunit of heterodimeric nuclear SUMO activating enzyme E1 with Aos1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TUB2 |
YFL037W |
Beta-tubulin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
VMA6 |
YLR447C |
Subunit d of the V0 integral membrane domain of V-ATPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TIF6 |
YPR016C |
Constituent of 66S pre-ribosomal particles |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TDH2 |
YJR009C |
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 2 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TDH1 |
YJL052W |
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 1 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TAF9 |
YMR236W |
Subunit (17 kDa) of TFIID and SAGA complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
UBI4 |
YLL039C |
Ubiquitin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
UBP6 |
YFR010W |
Ubiquitin-specific protease |
genetic |
1 |
1 |
1 |
Negative Genetic |
TOP3 |
YLR234W |
DNA Topoisomerase III |
genetic |
1 |
1 |
1 |
Negative Genetic |
YTA7 |
YGR270W |
Chromatin-binding ATPase that regulates histone gene expression |
genetic |
1 |
1 |
1 |
Negative Genetic |
UBC7 |
YMR022W |
Ubiquitin conjugating enzyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
TGL2 |
YDR058C |
Triacylglycerol lipase that is localized to the mitochondria |
genetic |
1 |
1 |
1 |
Negative Genetic |
VSB1 |
YGR125W |
Vacuolar membrane protein required for uptake and storage of arginine |
genetic |
1 |
1 |
1 |
Positive Genetic |
TTI2 |
YJR136C |
Subunit of the ASTRA complex, involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Positive Genetic |
YKT6 |
YKL196C |
Vesicle membrane protein (v-SNARE) with acyltransferase activity |
genetic |
1 |
1 |
1 |
Positive Genetic |
YJU2 |
YKL095W |
Essential protein required for pre-mRNA splicing |
genetic |
1 |
1 |
1 |
Positive Genetic |
YAK1 |
YJL141C |
Serine-threonine protein kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
YJR084W |
YJR084W |
Protein that forms a complex with Thp3p |
genetic |
1 |
1 |
1 |
Positive Genetic |
TRM11 |
YOL124C |
Catalytic subunit of adoMet-dependent tRNA methyltransferase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
VPS4 |
YPR173C |
AAA-ATPase involved in multivesicular body (MVB) protein sorting |
genetic |
1 |
1 |
1 |
Positive Genetic |
VHT1 |
YGR065C |
High-affinity plasma membrane H+-biotin (vitamin H) symporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
TFB1 |
YDR311W |
Subunit of TFIIH and nucleotide excision repair factor 3 complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
TOR2 |
YKL203C |
PIK-related protein kinase and rapamycin target |
genetic |
1 |
1 |
1 |
Negative Genetic |
TOA1 |
YOR194C |
TFIIA large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
YOS9 |
YDR057W |
ER quality-control lectin |
genetic |
1 |
1 |
1 |
Negative Genetic |
YGL176C |
YGL176C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YIL161W |
YIL161W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
TOP1 |
YOL006C |
Topoisomerase I |
genetic |
1 |
1 |
1 |
Negative Genetic |
YOR105W |
YOR105W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
VAC7 |
YNL054W |
Integral vacuolar membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
SWI1 |
YPL016W |
Subunit of the SWI/SNF chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS7A |
YOR096W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS22A |
YJL190C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BUR6 |
YER159C |
Subunit of a heterodimeric NC2 transcription regulator complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
CTF8 |
YHR191C |
Subunit of a complex with Ctf18p |
genetic |
1 |
1 |
1 |
Negative Genetic |
GIM4 |
YEL003W |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
ECO1 |
YFR027W |
Acetyltransferase required for sister chromatid cohesion |
genetic |
1 |
1 |
1 |
Negative Genetic |
NRG2 |
YBR066C |
Transcriptional repressor |
genetic |
1 |
1 |
1 |
Negative Genetic |
CBF2 |
YGR140W |
Essential kinetochore protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
STN1 |
YDR082W |
Telomere end-binding and capping protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
STU1 |
YBL034C |
Microtubule plus-end-tracking non-motor protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
STP22 |
YCL008C |
Component of the ESCRT-I complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
PEP8 |
YJL053W |
Vacuolar protein component of the retromer |
genetic |
1 |
1 |
1 |
Negative Genetic |
HSF1 |
YGL073W |
Trimeric heat shock transcription factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
KAR2 |
YJL034W |
ATPase involved in protein import into the ER |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MOB1 |
YIL106W |
Component of the mitotic exit network |
genetic |
1 |
1 |
1 |
Negative Genetic |
MPT5 |
YGL178W |
mRNA-binding protein of the PUF family |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
SPT10 |
YJL127C |
Histone H3 acetylase with a role in transcriptional regulation |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
STE50 |
YCL032W |
Adaptor protein for various signaling pathways |
genetic |
1 |
1 |
1 |
Negative Genetic |
MCM7 |
YBR202W |
Component of the Mcm2-7 hexameric helicase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
BCH1 |
YMR237W |
Member of the ChAPs family (Chs5p-Arf1p-binding proteins) |
genetic |
1 |
1 |
1 |
Dosage Rescue |
RPL1A |
YPL220W |
Ribosomal 60S subunit protein L1A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PFY1 |
YOR122C |
Profilin |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRI1 |
YIR008C |
Subunit of DNA primase |
genetic |
1 |
1 |
1 |
Negative Genetic |
HHT2 |
YNL031C |
Histone H3 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SWC3 |
YAL011W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS2 |
YGL123W |
Protein component of the small (40S) subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS3 |
YNL178W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BET4 |
YJL031C |
Alpha subunit of Type II geranylgeranyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
ERV14 |
YGL054C |
COPII-coated vesicle protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
SSB2 |
YNL209W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
1 |
1 |
1 |
Co-purification |
SOH1 |
YGL127C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
MOG1 |
YJR074W |
Conserved nuclear protein that interacts with GTP-Gsp1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS14A |
YCR031C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL19B |
YBL027W |
Ribosomal 60S subunit protein L19B |
genetic |
1 |
1 |
1 |
Negative Genetic |
DPM1 |
YPR183W |
Dolichol phosphate mannose (Dol-P-Man) synthase of ER membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC39 |
YLR440C |
Component of the Dsl1p tethering complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRC1 |
YCL061C |
S-phase checkpoint protein required for DNA replication |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
COY1 |
YKL179C |
Golgi membrane protein with similarity to mammalian CASP |
genetic |
1 |
1 |
1 |
Negative Genetic |
SLK19 |
YOR195W |
Kinetochore-associated protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
AUA1 |
YFL010W-A |
Protein required for the negative regulation by ammonia of Gap1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
BTS1 |
YPL069C |
Geranylgeranyl diphosphate synthase (GGPPS) |
genetic |
1 |
1 |
1 |
Positive Genetic |
ATP14 |
YLR295C |
Subunit h of the F0 sector of mitochondrial F1F0 ATP synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERG7 |
YHR072W |
Lanosterol synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
HRD3 |
YLR207W |
ER membrane protein that plays a central role in ERAD |
genetic |
1 |
1 |
1 |
Negative Genetic |
ASE1 |
YOR058C |
Mitotic spindle midzone-localized microtubule bundling protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
HRQ1 |
YDR291W |
3'-5' DNA helicase of the conserved RecQ family |
genetic |
1 |
1 |
1 |
Negative Genetic |
SLF1 |
YDR515W |
RNA binding protein that associates with polysomes |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
KIN4 |
YOR233W |
Serine/threonine protein kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
RAD27 |
YKL113C |
5' to 3' exonuclease, 5' flap endonuclease |
genetic |
1 |
1 |
1 |
Negative Genetic |
SLX4 |
YLR135W |
Endonuclease involved in processing DNA |
genetic |
1 |
1 |
1 |
Positive Genetic |
AIM26 |
YKL037W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
ECM3 |
YOR092W |
Non-essential protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
SFB2 |
YNL049C |
Component of the Sec23p-Sfb2p heterodimer of the COPII vesicle coat |
genetic |
1 |
1 |
1 |
Negative Genetic |
SWA2 |
YDR320C |
Auxilin-like protein involved in vesicular transport |
genetic |
1 |
1 |
1 |
Positive Genetic |
ROX1 |
YPR065W |
Heme-dependent repressor of hypoxic genes |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL12A |
YEL054C |
Ribosomal 60S subunit protein L12A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS9A |
YPL081W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL20A |
YMR242C |
Ribosomal 60S subunit protein L20A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS10A |
YOR293W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL35A |
YDL191W |
Ribosomal 60S subunit protein L35A |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPP2A |
YOL039W |
Ribosomal protein P2 alpha |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
IPT1 |
YDR072C |
Inositolphosphotransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPL34A |
YER056C-A |
Ribosomal 60S subunit protein L34A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
APJ1 |
YNL077W |
Hsp40 chaperone with a role in SUMO-mediated protein degradation |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
AIM11 |
YER093C-A |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
PYP1 |
YNL010W |
Sugar alcohol phosphatase |
genetic |
1 |
1 |
1 |
Positive Genetic |
MDM38 |
YOL027C |
Membrane-associated mitochondrial ribosome receptor |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL14A |
YKL006W |
Ribosomal 60S subunit protein L14A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RDL1 |
YOR285W |
Thiosulfate sulfurtransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
NCB2 |
YDR397C |
Subunit of a heterodimeric NC2 transcription regulator complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
PTR2 |
YKR093W |
Integral membrane peptide transporter |
genetic |
1 |
1 |
1 |
Positive Genetic |
RTC1 |
YOL138C |
Subunit of SEACAT, a subcomplex of the SEA complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RIB5 |
YBR256C |
Riboflavin synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRL1 |
YPR079W |
Membrane protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NNR2 |
YKL151C |
Widely-conserved NADHX dehydratase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MSN1 |
YOL116W |
Transcriptional activator |
genetic |
1 |
1 |
1 |
Positive Genetic |
HAL9 |
YOL089C |
Putative transcription factor containing a zinc finger |
genetic |
1 |
1 |
1 |
Negative Genetic |
DIT1 |
YDR403W |
Sporulation-specific enzyme required for spore wall maturation |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NCW1 |
YMR122W-A |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
QCR9 |
YGR183C |
Subunit 9 of ubiquinol cytochrome-c reductase (Complex III) |
genetic |
1 |
1 |
1 |
Negative Genetic |
NCS6 |
YGL211W |
Protein required for uridine thiolation of Gln, Lys, and Glu tRNAs |
genetic |
1 |
1 |
1 |
Negative Genetic |
MTC3 |
YGL226W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
LDS2 |
YOL047C |
Protein Involved in spore wall assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
SRP102 |
YKL154W |
Signal recognition particle (SRP) receptor beta subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
FLX1 |
YIL134W |
Mitochondrial flavin adenine dinucleotide transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
GAS4 |
YOL132W |
1,3-beta-glucanosyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SVL3 |
YPL032C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRX19 |
YDL183C |
Protein that may form an active mitochondrial KHE system |
genetic |
1 |
1 |
1 |
Negative Genetic |
RIB2 |
YOL066C |
Bifunctional DRAP deaminase tRNA:pseudouridine synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SLD3 |
YGL113W |
Protein involved in the initiation of DNA replication |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS30B |
YOR182C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS21B |
YJL136C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
OPI10 |
YOL032W |
Protein with a possible role in phospholipid biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
SND2 |
YLR065C |
Protein involved in SRP-independent targeting of substrates to the ER |
genetic |
1 |
1 |
1 |
Positive Genetic |
SEC12 |
YNR026C |
Guanine nucleotide exchange factor (GEF) |
genetic |
1 |
1 |
1 |
Negative Genetic |
RRF1 |
YHR038W |
Mitochondrial ribosome recycling factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
RTC6 |
YPL183W-A |
Protein involved in translation |
genetic |
1 |
1 |
1 |
Negative Genetic |
FRE7 |
YOL152W |
Putative ferric reductase with similarity to Fre2p |
genetic |
1 |
1 |
1 |
Positive Genetic |
MMO1 |
YKL044W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |