Standard name Systematic name Name description Description
STE20 YHL007C Cdc42p-activated signal transducing kinase Cdc42p-activated signal transducing kinase; involved in pheromone response, pseudohyphal/invasive growth, vacuole inheritance, down-regulation of sterol uptake; GBB motif binds Ste4p; member of the PAK (p21-activated kinase) family
Visualize the interactome of STE20
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Bud 0.090 NaN 0.149
Cell Periphery 0.154 NaN 0.158
Cort. Patches 0.224 0.095 0.232
Cytoplasm 0.538 0.810 0.627
ER 0.128 0.095 0.066

GFP localization & abundance

GFP localization GFP abundance
cytoplasm, bud 259

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
STE20 2 1 4 7 0

Enzyme information

Catalyzed reactions in Yeast8

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
CDC42 YLR229C Small rho-like GTPase physical 20 4 18 Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Reconstituted Complex, Two-hybrid, Two-hybrid, Biochemical Activity, Two-hybrid, Two-hybrid, Two-hybrid, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western
BEM1 YBR200W Protein containing SH3-domains physical 15 7 12 Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Affinity Capture-Western, Biochemical Activity, PCA, PCA, Two-hybrid, Co-crystal Structure, Reconstituted Complex, PCA, Protein-peptide, Protein-peptide, Affinity Capture-Western
CLA4 YNL298W Cdc42p-activated signal transducing kinase genetic 13 5 13 Synthetic Lethality, Phenotypic Enhancement, Synthetic Growth Defect, Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect, Synthetic Lethality, Negative Genetic, Synthetic Growth Defect, Synthetic Lethality, Synthetic Lethality, Dosage Rescue, Phenotypic Enhancement
LTE1 YAL024C Protein similar to GDP/GTP exchange factors genetic 9 3 8 Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect, Dosage Rescue, Synthetic Lethality
CDC42 YLR229C Small rho-like GTPase genetic 8 3 7 Dosage Rescue, Dosage Rescue, Dosage Rescue, Dosage Rescue, Synthetic Rescue, Synthetic Rescue, Phenotypic Suppression, Phenotypic Suppression
NBP2 YDR162C Protein involved in the HOG (high osmolarity glycerol) pathway physical 8 6 5 Two-hybrid, Affinity Capture-Western, Two-hybrid, PCA, Reconstituted Complex, Protein-peptide, Co-crystal Structure, Protein-peptide
CLN2 YPL256C G1 cyclin involved in regulation of the cell cycle physical 7 2 5 Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western
STE11 YLR362W Signal transducing MEK kinase genetic 6 3 5 Phenotypic Enhancement, Phenotypic Suppression, Phenotypic Suppression, Dosage Rescue, Phenotypic Suppression, Phenotypic Suppression
STE12 YHR084W Transcription factor that is activated by a MAPK signaling cascade genetic 4 2 4 Dosage Rescue, Dosage Rescue, Phenotypic Enhancement, Dosage Rescue
MSB2 YGR014W Mucin family member involved in various signaling pathways genetic 3 3 3 Phenotypic Suppression, Synthetic Rescue, Synthetic Growth Defect
CDC24 YAL041W Guanine nucleotide exchange factor (GEF) for Cdc42p physical 3 2 3 Two-hybrid, PCA, Two-hybrid
SSK2 YNR031C MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway genetic 3 2 3 Phenotypic Enhancement, Synthetic Growth Defect, Synthetic Growth Defect
HOG1 YLR113W Mitogen-activated protein kinase involved in osmoregulation genetic 3 2 3 Phenotypic Suppression, Phenotypic Suppression, Dosage Growth Defect
SSK22 YCR073C MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway genetic 3 2 3 Phenotypic Enhancement, Synthetic Growth Defect, Synthetic Growth Defect
STE11 YLR362W Signal transducing MEK kinase physical 3 1 3 Biochemical Activity, Biochemical Activity, Biochemical Activity
STE4 YOR212W G protein beta subunit genetic 3 3 2 Phenotypic Enhancement, Synthetic Rescue, Dosage Rescue
BOI1 YBL085W Protein involved in polar growth, functionally redundant with Boi2p physical 3 2 2 Two-hybrid, Two-hybrid, Biochemical Activity
STE4 YOR212W G protein beta subunit physical 3 2 2 Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western
VMA13 YPR036W Subunit H of the V1 peripheral membrane domain of V-ATPase physical 3 2 1 PCA, Affinity Capture-Western, Affinity Capture-Western
BEM1 YBR200W Protein containing SH3-domains genetic 2 2 2 Dosage Rescue, Synthetic Rescue
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit physical 2 2 2 Biochemical Activity, Affinity Capture-MS
BCK1 YJL095W MAPKKK acting in the protein kinase C signaling pathway genetic 2 2 2 Negative Genetic, Dosage Growth Defect
CBK1 YNL161W Serine/threonine protein kinase of the the RAM signaling network physical 2 2 2 Two-hybrid, Affinity Capture-MS
SSK1 YLR006C Cytoplasmic phosphorelay intermediate osmosensor and regulator genetic 2 2 2 Phenotypic Enhancement, Synthetic Growth Defect
SPO12 YHR152W Nucleolar protein of unknown function genetic 2 2 2 Synthetic Rescue, Synthetic Lethality
RAS2 YNL098C GTP-binding protein genetic 2 2 2 Dosage Rescue, Synthetic Rescue
SLT2 YHR030C Serine/threonine MAP kinase genetic 2 2 2 Negative Genetic, Dosage Growth Defect
SKM1 YOL113W Member of the PAK family of serine/threonine protein kinases genetic 2 2 2 Dosage Rescue, Synthetic Growth Defect
GIC1 YHR061C Rho-family GTPase interacting protein and Cdc42p effector genetic 2 2 2 Synthetic Rescue, Dosage Rescue
GIC2 YDR309C Rho-family GTPase interacting protein and Cdc42p effector genetic 2 2 2 Synthetic Rescue, Dosage Rescue
SHO1 YER118C Transmembrane osmosensor for filamentous growth and HOG pathways physical 2 2 2 Two-hybrid, Affinity Capture-Western
RSR1 YGR152C Ras-type GTPase genetic 2 2 2 Synthetic Growth Defect, Synthetic Rescue
OCH1 YGL038C Mannosyltransferase of the cis-Golgi apparatus genetic 2 2 2 Synthetic Lethality, Synthetic Growth Defect
KIN4 YOR233W Serine/threonine protein kinase genetic 2 2 2 Synthetic Rescue, Synthetic Lethality
SPT16 YGL207W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) physical 2 1 2 Biochemical Activity, Biochemical Activity
BMS1 YPL217C GTPase required for ribosomal subunit synthesis and rRNA processing physical 2 1 2 Biochemical Activity, Biochemical Activity
CDC3 YLR314C Component of the septin ring that is required for cytokinesis physical 2 1 2 Biochemical Activity, Biochemical Activity
BUB2 YMR055C Mitotic exit network regulator genetic 2 1 2 Synthetic Rescue, Synthetic Rescue
STE20 YHL007C Cdc42p-activated signal transducing kinase physical 2 1 2 Biochemical Activity, Biochemical Activity
STE5 YDR103W Pheromone-responsive MAPK scaffold protein genetic 2 1 2 Dosage Rescue, Dosage Rescue
HSL7 YBR133C Protein arginine N-methyltransferase physical 2 2 1 Affinity Capture-Western, Two-hybrid
CBR1 YIL043C Cytochrome b reductase and NADH-dependent reductase for Dph3p physical 2 2 1 PCA, Affinity Capture-Western
SUT1 YGL162W Zn(II)2Cys6 family transcription factor physical 2 2 1 Affinity Capture-Western, Two-hybrid
AIM44 YPL158C Regulator of Cdc42p and Rho1p genetic 2 2 1 Synthetic Lethality, Dosage Rescue
ERG4 YGL012W C-24(28) sterol reductase physical 2 2 1 PCA, Affinity Capture-Western
BOI2 YER114C Protein involved in polar growth physical 2 1 1 Two-hybrid, Two-hybrid
HDA1 YNL021W Catalytic subunit of class II HDA1 histone deacetylase complex genetic 2 1 1 Dosage Lethality, Dosage Lethality
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
TAF9 YMR236W Subunit (17 kDa) of TFIID and SAGA complexes genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
SSB1 YDL229W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MED2 YDL005C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RGR1 YLR071C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
XBP1 YIL101C Transcriptional repressor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit regulation 1 1 1 quantitative mass spectrometry evidence
MED4 YOR174W Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SPT3 YDR392W Subunit of the SAGA and SAGA-like transcriptional regulatory complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SPT7 YBR081C Subunit of the SAGA transcriptional regulatory complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
HOG1 YLR113W Mitogen-activated protein kinase involved in osmoregulation regulation 1 1 1 mass spectrometry evidence
ALD3 YMR169C Cytoplasmic aldehyde dehydrogenase regulation 1 1 1 chromatin immunoprecipitation-qPCR evidence
HHF2 YNL030W Histone H4 regulation 1 1 1 protein kinase assay evidence
HHF1 YBR009C Histone H4 regulation 1 1 1 protein kinase assay evidence
HSP12 YFL014W Plasma membrane protein involved in maintaining membrane organization regulation 1 1 1 chromatin immunoprecipitation-qPCR evidence
CKB1 YGL019W Beta regulatory subunit of casein kinase 2 (CK2) physical 1 1 1 Reconstituted Complex
DRS1 YLL008W Nucleolar DEAD-box protein required for ribosome assembly and function physical 1 1 1 Reconstituted Complex
ERB1 YMR049C Constituent of 66S pre-ribosomal particles physical 1 1 1 Affinity Capture-MS
RIC1 YLR039C Protein involved in retrograde transport to the cis-Golgi network genetic 1 1 1 Positive Genetic
FRT2 YAL028W Tail-anchored ER membrane protein of unknown function physical 1 1 1 Biochemical Activity
KES1 YPL145C Sterol/phosphatidylinositol-4-phosphate (PI(4)P) exchanger genetic 1 1 1 Synthetic Lethality
GUS1 YGL245W Glutamyl-tRNA synthetase (GluRS) physical 1 1 1 Biochemical Activity
BMH1 YER177W 14-3-3 protein, major isoform physical 1 1 1 Affinity Capture-Western
NSR1 YGR159C Nucleolin, nucleolar protein that binds nuclear localization sequences physical 1 1 1 Biochemical Activity
LSM6 YDR378C Lsm (Like Sm) protein genetic 1 1 1 Positive Genetic
CDC33 YOL139C Translation initiation factor eIF4E physical 1 1 1 Biochemical Activity
RPB5 YBR154C RNA polymerase subunit ABC27 physical 1 1 1 Biochemical Activity
RSC6 YCR052W Component of the RSC chromatin remodeling complex physical 1 1 1 Biochemical Activity
RSC8 YFR037C Component of the RSC chromatin remodeling complex physical 1 1 1 Biochemical Activity
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 1 1 1 Synthetic Haploinsufficiency
SSD1 YDR293C Translational repressor physical 1 1 1 Biochemical Activity
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
BMH2 YDR099W 14-3-3 protein, minor isoform physical 1 1 1 Affinity Capture-Western
ASC1 YMR116C G-protein beta subunit and guanine dissociation inhibitor for Gpa2p physical 1 1 1 Affinity Capture-Western
BEM2 YER155C Rho GTPase activating protein (RhoGAP) genetic 1 1 1 Phenotypic Suppression
BUD14 YAR014C Protein involved in bud-site selection genetic 1 1 1 Positive Genetic
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit genetic 1 1 1 Phenotypic Enhancement
BNI1 YNL271C Formin physical 1 1 1 Biochemical Activity
CDC55 YGL190C Regulatory subunit B of protein phosphatase 2A (PP2A) genetic 1 1 1 Negative Genetic
DCP2 YNL118C Catalytic subunit of Dcp1p-Dcp2p decapping enzyme complex physical 1 1 1 Biochemical Activity
DOA1 YKL213C WD-repeat protein involved in ubiquitin-mediated protein degradation genetic 1 1 1 Positive Genetic
EXO84 YBR102C Exocyst subunit with dual roles in exocytosis and spliceosome assembly physical 1 1 1 Biochemical Activity
GLO3 YER122C ADP-ribosylation factor GTPase activating protein (ARF GAP) physical 1 1 1 Biochemical Activity
BDF2 YDL070W Protein involved in transcription initiation physical 1 1 1 Biochemical Activity
HHF1 YBR009C Histone H4 physical 1 1 1 Biochemical Activity
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
HTB2 YBL002W Histone H2B physical 1 1 1 Biochemical Activity
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
KRS1 YDR037W Lysyl-tRNA synthetase physical 1 1 1 Biochemical Activity
CRM1 YGR218W Nuclear export factor, exportin physical 1 1 1 Affinity Capture-MS
HRR25 YPL204W Conserved casein kinase, monopolin subunit genetic 1 1 1 Negative Genetic
MRPL36 YBR122C Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Biochemical Activity
MLC1 YGL106W Essential light chain for Myo1p physical 1 1 1 PCA
GIN4 YDR507C Protein kinase involved in bud growth and assembly of the septin ring genetic 1 1 1 Negative Genetic
GIM5 YML094W Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Negative Genetic
PPH22 YDL188C Catalytic subunit of protein phosphatase 2A, PP2A genetic 1 1 1 Positive Genetic
PRP21 YJL203W Subunit of the SF3a splicing factor complex physical 1 1 1 Two-hybrid
RAM1 YDL090C Beta subunit of the CAAX farnesyltransferase (FTase) genetic 1 1 1 Negative Genetic
PUP3 YER094C Beta 3 subunit of the 20S proteasome genetic 1 1 1 Synthetic Rescue
MNN10 YDR245W Subunit of a Golgi mannosyltransferase complex genetic 1 1 1 Negative Genetic
AVT4 YNL101W Vacuolar transporter physical 1 1 1 Biochemical Activity
RPT5 YOR117W ATPase of the 19S regulatory particle of the 26S proteasome physical 1 1 1 Biochemical Activity
SGV1 YPR161C Cyclin (Bur2p)-dependent protein kinase physical 1 1 1 Biochemical Activity
IST2 YBR086C Cortical ER protein involved in ER-plasma membrane (PM) tethering physical 1 1 1 Biochemical Activity
PTC1 YDL006W Type 2C protein phosphatase (PP2C) physical 1 1 1 PCA
PSK1 YAL017W PAS domain-containing serine/threonine protein kinase genetic 1 1 1 Negative Genetic
SBP1 YHL034C Protein that binds eIF4G and has a role in repression of translation physical 1 1 1 Affinity Capture-RNA
ATG9 YDL149W Transmembrane protein involved in forming Cvt and autophagic vesicles physical 1 1 1 Biochemical Activity
RAD1 YPL022W Single-stranded DNA endonuclease (with Rad10p) physical 1 1 1 Affinity Capture-MS
HEK2 YBL032W RNA binding protein involved in asymmetric localization of ASH1 mRNA physical 1 1 1 Affinity Capture-RNA
CRZ1 YNL027W Transcription factor, activates transcription of stress response genes physical 1 1 1 Biochemical Activity
PHO85 YPL031C Cyclin-dependent kinase genetic 1 1 1 Dosage Lethality
SPS1 YDR523C STE20-family GCKIII protein kinase genetic 1 1 1 Negative Genetic
MGE1 YOR232W Mitochondrial matrix cochaperone physical 1 1 1 Biochemical Activity
HTB1 YDR224C Histone H2B physical 1 1 1 Biochemical Activity
GSP1 YLR293C Ran GTPase physical 1 1 1 Biochemical Activity
MPC54 YOR177C Component of the meiotic outer plaque physical 1 1 1 Biochemical Activity
CLN1 YMR199W G1 cyclin involved in regulation of the cell cycle physical 1 1 1 Affinity Capture-Western
SES1 YDR023W Cytosolic seryl-tRNA synthetase physical 1 1 1 Biochemical Activity
ELM1 YKL048C Serine/threonine protein kinase genetic 1 1 1 Phenotypic Suppression
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 1 1 1 Positive Genetic
ARE2 YNR019W Acyl-CoA:sterol acyltransferase physical 1 1 1 Biochemical Activity
HSL7 YBR133C Protein arginine N-methyltransferase genetic 1 1 1 Synthetic Rescue
PTP3 YER075C Phosphotyrosine-specific protein phosphatase genetic 1 1 1 Synthetic Rescue
EST1 YLR233C TLC1 RNA-associated factor involved in telomere length regulation genetic 1 1 1 Synthetic Growth Defect
BEM3 YPL115C Rho GTPase activating protein (RhoGAP) genetic 1 1 1 Synthetic Growth Defect
SHE3 YBR130C Protein adaptor between Myo4p and the She2p-mRNA complex physical 1 1 1 Biochemical Activity
SLT2 YHR030C Serine/threonine MAP kinase physical 1 1 1 Biochemical Activity
RCK1 YGL158W Protein kinase involved in oxidative stress response genetic 1 1 1 Positive Genetic
BEM4 YPL161C Protein involved in establishment of cell polarity and bud emergence physical 1 1 1 Two-hybrid
PTP2 YOR208W Phosphotyrosine-specific phosphatase physical 1 1 1 Biochemical Activity
PTP2 YOR208W Phosphotyrosine-specific phosphatase genetic 1 1 1 Synthetic Rescue
CLB2 YPR119W B-type cyclin involved in cell cycle progression physical 1 1 1 Affinity Capture-Western
CLB2 YPR119W B-type cyclin involved in cell cycle progression genetic 1 1 1 Synthetic Rescue
RAD53 YPL153C DNA damage response kinase physical 1 1 1 Biochemical Activity
DUT1 YBR252W Deoxyuridine triphosphate diphosphatase (dUTPase) genetic 1 1 1 Negative Genetic
PPZ1 YML016C Serine/threonine protein phosphatase Z, isoform of Ppz2p genetic 1 1 1 Negative Genetic
MSG5 YNL053W Dual-specificity protein phosphatase genetic 1 1 1 Positive Genetic
FUS3 YBL016W Mitogen-activated serine/threonine protein kinase involved in mating genetic 1 1 1 Phenotypic Suppression
NUP53 YMR153W FG-nucleoporin component of central core of nuclear pore complex (NPC) physical 1 1 1 Biochemical Activity
CLN2 YPL256C G1 cyclin involved in regulation of the cell cycle genetic 1 1 1 Phenotypic Suppression
PMI40 YER003C Mannose-6-phosphate isomerase genetic 1 1 1 Synthetic Growth Defect
CIN5 YOR028C Basic leucine zipper (bZIP) transcription factor of the yAP-1 family physical 1 1 1 Biochemical Activity
CNM1 YBR063C Molecular tether on nuclear membrane physical 1 1 1 Biochemical Activity
KKQ8 YKL168C Putative serine/threonine protein kinase with unknown cellular role genetic 1 1 1 Negative Genetic
NBP2 YDR162C Protein involved in the HOG (high osmolarity glycerol) pathway genetic 1 1 1 Dosage Lethality
CLN3 YAL040C G1 cyclin involved in cell cycle progression genetic 1 1 1 Positive Genetic
EBS1 YDR206W Protein involved in translation inhibition and nonsense-mediated decay physical 1 1 1 Affinity Capture-MS
IRE1 YHR079C Serine-threonine kinase and endoribonuclease genetic 1 1 1 Synthetic Growth Defect
PCL2 YDL127W Cyclin, interacts with cyclin-dependent kinase Pho85p genetic 1 1 1 Negative Genetic
ALY2 YJL084C Alpha arrestin, Ub-ligase adaptor for Rsp5p physical 1 1 1 Biochemical Activity
RGA1 YOR127W GTPase-activating protein for polarity-regulator Cdc42p (RhoGAP) genetic 1 1 1 Synthetic Growth Defect
RRN6 YBL014C Component of the core factor (CF) rDNA transcription factor complex physical 1 1 1 Biochemical Activity
AIM3 YBR108W Protein that inhibits barbed-end actin filament elongation physical 1 1 1 Biochemical Activity
CDC34 YDR054C Ubiquitin-conjugating enzyme (E2) genetic 1 1 1 Synthetic Rescue
STB2 YMR053C Protein that interacts with Sin3p in a two-hybrid assay physical 1 1 1 Biochemical Activity
PPA2 YMR267W Mitochondrial inorganic pyrophosphatase genetic 1 1 1 Positive Genetic
SPB1 YCL054W AdoMet-dependent methyltransferase physical 1 1 1 Biochemical Activity
PRR1 YKL116C Serine/threonine protein kinase genetic 1 1 1 Positive Genetic
COG4 YPR105C Essential component of the conserved oligomeric Golgi complex physical 1 1 1 Biochemical Activity
CLB1 YGR108W B-type cyclin involved in cell cycle progression physical 1 1 1 Biochemical Activity
ELP3 YPL086C Subunit of Elongator complex genetic 1 1 1 Negative Genetic
RPS13 YDR064W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
BRF1 YGR246C TFIIIB B-related factor physical 1 1 1 Affinity Capture-MS
SKO1 YNL167C Basic leucine zipper transcription factor of the ATF/CREB family genetic 1 1 1 Phenotypic Suppression
PHO4 YFR034C Basic helix-loop-helix (bHLH) transcription factor of the myc-family genetic 1 1 1 Negative Genetic
RPS1A YLR441C Ribosomal protein of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPS8A YBL072C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS7A YOR096W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
CSE4 YKL049C Centromeric histone H3-like protein physical 1 1 1 Affinity Capture-MS
BFR1 YOR198C Component of mRNP complexes associated with polyribosomes physical 1 1 1 Affinity Capture-RNA
BUB1 YGR188C Protein kinase involved in the cell cycle checkpoint into anaphase genetic 1 1 1 Negative Genetic
BUD4 YJR092W Anillin-like protein involved in bud-site selection genetic 1 1 1 Synthetic Rescue
CLB5 YPR120C B-type cyclin involved in DNA replication during S phase physical 1 1 1 Affinity Capture-Western
FRQ1 YDR373W N-myristoylated calcium-binding protein genetic 1 1 1 Negative Genetic
MYO3 YKL129C One of two type I myosins physical 1 1 1 Biochemical Activity
ATS1 YAL020C Protein required for modification of wobble nucleosides in tRNA physical 1 1 1 Biochemical Activity
SEC22 YLR268W R-SNARE protein genetic 1 1 1 Positive Genetic
RRD1 YIL153W Peptidyl-prolyl cis/trans-isomerase genetic 1 1 1 Negative Genetic
SRO7 YPR032W Effector of Rab GTPase Sec4p physical 1 1 1 Biochemical Activity
UBX7 YBR273C UBX (ubiquitin regulatory X) domain-containing protein physical 1 1 1 Biochemical Activity
YML083C YML083C Protein of unknown function physical 1 1 1 Biochemical Activity
UBP9 YER098W Ubiquitin-specific protease that cleaves ubiquitin-protein fusions physical 1 1 1 Biochemical Activity
YBR071W YBR071W Protein of unknown function found in the cytoplasm and bud neck physical 1 1 1 Biochemical Activity
YHR131C YHR131C Putative protein of unknown function physical 1 1 1 Biochemical Activity
TRP2 YER090W Anthranilate synthase physical 1 1 1 Biochemical Activity
UBX5 YDR330W UBX domain-containing protein that interacts with Cdc48p physical 1 1 1 Biochemical Activity
YML037C YML037C Putative protein of unknown function physical 1 1 1 Biochemical Activity
YML096W YML096W Putative protein with similarity to asparagine synthetases physical 1 1 1 Biochemical Activity
UBP7 YIL156W Ubiquitin-specific protease that cleaves ubiquitin-protein fusions physical 1 1 1 Biochemical Activity
THO1 YER063W Conserved nuclear RNA-binding protein physical 1 1 1 Biochemical Activity
YIG1 YPL201C Protein that interacts with glycerol 3-phosphatase physical 1 1 1 Reconstituted Complex
VMA13 YPR036W Subunit H of the V1 peripheral membrane domain of V-ATPase genetic 1 1 1 Synthetic Growth Defect
UTP5 YDR398W Subunit of U3-containing Small Subunit (SSU) processome complex physical 1 1 1 Biochemical Activity
UTP7 YER082C Nucleolar protein physical 1 1 1 Biochemical Activity
TOM1 YDR457W E3 ubiquitin ligase of the hect-domain class physical 1 1 1 Affinity Capture-MS
SWE1 YJL187C Protein kinase that regulates the G2/M transition genetic 1 1 1 Synthetic Lethality
UBA4 YHR111W E1-like protein that activates Urm1p before urmylation genetic 1 1 1 Phenotypic Enhancement
URM1 YIL008W Ubiquitin-like protein involved in thiolation of cytoplasmic tRNAs genetic 1 1 1 Phenotypic Enhancement
TEM1 YML064C GTPase involved in initiation of Mitotic Exit Network (MEN) genetic 1 1 1 Synthetic Rescue
STE3 YKL178C Receptor for a factor pheromone genetic 1 1 1 Dosage Rescue
SWD3 YBR175W Essential subunit of the COMPASS (Set1C) complex genetic 1 1 1 Negative Genetic
STE50 YCL032W Adaptor protein for various signaling pathways genetic 1 1 1 Negative Genetic
VID30 YGL227W Central component of GID Complex, involved in FBPase degradation genetic 1 1 1 Positive Genetic
SYS1 YJL004C Integral membrane protein of the Golgi genetic 1 1 1 Negative Genetic
URA6 YKL024C Uridylate kinase genetic 1 1 1 Negative Genetic
TOS4 YLR183C Putative transcription factor, contains Forkhead Associated domain genetic 1 1 1 Negative Genetic
YPT6 YLR262C Rab family GTPase genetic 1 1 1 Positive Genetic
ZDS1 YMR273C Protein with a role in regulating Swe1p-dependent polarized growth genetic 1 1 1 Positive Genetic
TEP1 YNL128W PTEN homolog with no demonstrated inositol lipid phosphatase activity genetic 1 1 1 Negative Genetic
VPS30 YPL120W Subunit of phosphatidylinositol (PtdIns) 3-kinase complexes I and II genetic 1 1 1 Positive Genetic
THR1 YHR025W Homoserine kinase genetic 1 1 1 Positive Genetic
WHI2 YOR043W Negative regulator of TORC1 in response to limiting leucine genetic 1 1 1 Synthetic Rescue
TPK2 YPL203W cAMP-dependent protein kinase catalytic subunit genetic 1 1 1 Synthetic Growth Defect
VMA2 YBR127C Subunit B of V1 peripheral membrane domain of vacuolar H+-ATPase genetic 1 1 1 Synthetic Rescue
VMA3 YEL027W Proteolipid subunit c of the V0 domain of vacuolar H(+)-ATPase genetic 1 1 1 Synthetic Rescue
TUB4 YLR212C Gamma-tubulin genetic 1 1 1 Synthetic Growth Defect
BUD8 YLR353W Protein involved in bud-site selection physical 1 1 1 Two-hybrid
ERV46 YAL042W Protein localized to COPII-coated vesicles physical 1 1 1 Biochemical Activity
SEC2 YNL272C Guanyl-nucleotide exchange factor for the small G-protein Sec4p physical 1 1 1 Biochemical Activity
PCL5 YHR071W Cyclin genetic 1 1 1 Positive Genetic
BUD6 YLR319C Actin- and formin-interacting protein physical 1 1 1 Biochemical Activity
AKR1 YDR264C Palmitoyl transferase involved in protein palmitoylation genetic 1 1 1 Synthetic Rescue
INP53 YOR109W Polyphosphatidylinositol phosphatase genetic 1 1 1 Positive Genetic
FBP26 YJL155C Fructose-2,6-bisphosphatase, required for glucose metabolism genetic 1 1 1 Negative Genetic
HKR1 YDR420W Mucin family member that functions as an osmosensor in the HOG pathway genetic 1 1 1 Synthetic Rescue
RGA2 YDR379W GTPase-activating protein for polarity-establishment protein Cdc42p physical 1 1 1 PCA
RGA2 YDR379W GTPase-activating protein for polarity-establishment protein Cdc42p genetic 1 1 1 Synthetic Growth Defect
SHO1 YER118C Transmembrane osmosensor for filamentous growth and HOG pathways genetic 1 1 1 Phenotypic Suppression
AZF1 YOR113W Zinc-finger transcription factor physical 1 1 1 Biochemical Activity
SPO21 YOL091W Component of the meiotic outer plaque of the spindle pole body physical 1 1 1 Biochemical Activity
MSB4 YOL112W GTPase-activating protein of the Ras superfamily physical 1 1 1 Biochemical Activity
ENT2 YLR206W Epsin-like protein required for endocytosis and actin patch assembly physical 1 1 1 PCA
NCP1 YHR042W NADP-cytochrome P450 reductase physical 1 1 1 PCA
NCP1 YHR042W NADP-cytochrome P450 reductase genetic 1 1 1 Synthetic Growth Defect
RPL25 YOL127W Ribosomal 60S subunit protein L25 physical 1 1 1 Affinity Capture-MS
MNN11 YJL183W Subunit of a Golgi mannosyltransferase complex genetic 1 1 1 Positive Genetic
PMT4 YJR143C Protein O-mannosyltransferase genetic 1 1 1 Phenotypic Enhancement
RPS2 YGL123W Protein component of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPS3 YNL178W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
HAC1 YFL031W Basic leucine zipper (bZIP) transcription factor (ATF/CREB1 homolog) genetic 1 1 1 Synthetic Growth Defect
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
RPS20 YHL015W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS14A YCR031C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
MRC1 YCL061C S-phase checkpoint protein required for DNA replication physical 1 1 1 Biochemical Activity
CST26 YBR042C Acyltransferase physical 1 1 1 Biochemical Activity
GDA1 YEL042W Guanosine diphosphatase located in the Golgi genetic 1 1 1 Positive Genetic
PAH1 YMR165C Mg2+-dependent phosphatidate (PA) phosphatase physical 1 1 1 Biochemical Activity
SOL2 YCR073W-A Protein with a possible role in tRNA export physical 1 1 1 Biochemical Activity
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 1 1 1 Positive Genetic
NSI1 YDR026C RNA polymerase I termination factor physical 1 1 1 Biochemical Activity
PAM1 YDR251W Essential protein of unknown function physical 1 1 1 Biochemical Activity
PUF4 YGL014W Member of the PUF protein family physical 1 1 1 Affinity Capture-RNA
SAS10 YDL153C Subunit of U3-containing Small Subunit (SSU) processome complex physical 1 1 1 Biochemical Activity
ECM3 YOR092W Non-essential protein of unknown function physical 1 1 1 Biochemical Activity
SEC14 YMR079W Phosphatidylinositol/phosphatidylcholine transfer protein genetic 1 1 1 Dosage Rescue
RPS6A YPL090C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
PHO13 YDL236W Conserved phosphatase acting as a metabolite repair enzyme genetic 1 1 1 Positive Genetic
RIM4 YHL024W Putative RNA-binding protein physical 1 1 1 Biochemical Activity
RPS9A YPL081W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
SDD3 YOL098C Putative metalloprotease physical 1 1 1 Biochemical Activity
RPS10A YOR293W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL26A YLR344W Ribosomal 60S subunit protein L26A physical 1 1 1 Affinity Capture-MS
RPS12 YOR369C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS19A YOL121C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
EMA35 YCR100C Protein involved in protein sorting physical 1 1 1 Biochemical Activity
DUS1 YML080W Dihydrouridine synthase physical 1 1 1 Biochemical Activity
PCM1 YEL058W Essential N-acetylglucosamine-phosphate mutase physical 1 1 1 Biochemical Activity
NVJ2 YPR091C Lipid-binding ER protein, enriched at nucleus-vacuolar junctions (NVJ) physical 1 1 1 Biochemical Activity
RCM1 YNL022C rRNA m5C methyltransferase physical 1 1 1 Biochemical Activity
SCT1 YBL011W Glycerol 3-phosphate/dihydroxyacetone phosphate sn-1 acyltransferase physical 1 1 1 Biochemical Activity
RNH70 YGR276C 3'-5' exoribonuclease physical 1 1 1 Biochemical Activity
MDG1 YNL173C Plasma membrane protein physical 1 1 1 Biochemical Activity
MRX9 YDL027C Protein that associates with mitochondrial ribosome physical 1 1 1 Biochemical Activity
RPS27A YKL156W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
SPO14 YKR031C Phospholipase D genetic 1 1 1 Positive Genetic
MPS3 YJL019W Nuclear envelope protein physical 1 1 1 Affinity Capture-MS
SLG1 YOR008C Sensor-transducer of the stress-activated PKC1-MPK1 kinase pathway genetic 1 1 1 Dosage Rescue
HSP30 YCR021C Negative regulator of the H(+)-ATPase Pma1p physical 1 1 1 PCA
SIC1 YLR079W Cyclin-dependent kinase inhibitor (CKI) genetic 1 1 1 Synthetic Rescue
CHO2 YGR157W Phosphatidylethanolamine methyltransferase (PEMT) physical 1 1 1 Biochemical Activity
PIG1 YLR273C Putative targeting subunit for type-1 protein phosphatase Glc7p genetic 1 1 1 Positive Genetic
ALK2 YBL009W Atypical protein kinase genetic 1 1 1 Positive Genetic
RPS15 YOL040C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
SCS3 YGL126W Protein required for normal ER membrane biosynthesis in response to ER genetic 1 1 1 Positive Genetic
IRC21 YMR073C Protein of unknown function genetic 1 1 1 Negative Genetic
RRM3 YHR031C DNA helicase involved in rDNA replication and Ty1 transposition genetic 1 1 1 Positive Genetic