HRR25 |
YPL204W |
Conserved casein kinase, monopolin subunit |
physical |
6 |
4 |
5 |
Affinity Capture-MS, Biochemical Activity, Biochemical Activity, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-Western |
FKS1 |
YLR342W |
Catalytic subunit of 1,3-beta-D-glucan synthase |
genetic |
4 |
2 |
4 |
Synthetic Lethality, Negative Genetic, Synthetic Lethality, Negative Genetic |
PHO89 |
YBR296C |
Plasma membrane Na+/Pi cotransporter |
regulation |
4 |
4 |
2 |
beta-galactosidase reporter gene assay evidence, chromatin immunoprecipitation-PCR evidence, chromatin immunoprecipitation-seq evidence, DNA to cDNA expression microarray evidence |
CNB1 |
YKL190W |
Calcineurin B |
genetic |
3 |
3 |
3 |
Dosage Rescue, Synthetic Growth Defect, Synthetic Rescue |
SAC1 |
YKL212W |
Phosphatidylinositol phosphate phosphatase |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
TPK1 |
YJL164C |
cAMP-dependent protein kinase catalytic subunit |
physical |
3 |
2 |
2 |
Affinity Capture-Western, Biochemical Activity, Biochemical Activity |
NEO1 |
YIL048W |
Phospholipid translocase (flippase) |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
UBP6 |
YFR010W |
Ubiquitin-specific protease |
genetic |
2 |
2 |
2 |
Phenotypic Enhancement, Negative Genetic |
RVS161 |
YCR009C |
Amphiphysin-like lipid raft protein |
genetic |
2 |
2 |
2 |
Positive Genetic, Negative Genetic |
PHO85 |
YPL031C |
Cyclin-dependent kinase |
physical |
2 |
1 |
2 |
Biochemical Activity, Biochemical Activity |
PHO85 |
YPL031C |
Cyclin-dependent kinase |
genetic |
2 |
1 |
2 |
Dosage Lethality, Dosage Lethality |
ISC1 |
YER019W |
Inositol phosphosphingolipid phospholipase C |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
GET2 |
YER083C |
Subunit of the GET complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
GET1 |
YGL020C |
Subunit of the GET complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
VMA8 |
YEL051W |
Subunit D of the V1 peripheral membrane domain of V-ATPase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
TSC11 |
YER093C |
Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
TOR2 |
YKL203C |
PIK-related protein kinase and rapamycin target |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
DAK1 |
YML070W |
Dihydroxyacetone kinase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
UBP2 |
YOR124C |
Ubiquitin-specific protease |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
UME6 |
YDR207C |
Rpd3L histone deacetylase complex subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
VPS1 |
YKR001C |
Dynamin-like GTPase required for vacuolar sorting |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RIC1 |
YLR039C |
Protein involved in retrograde transport to the cis-Golgi network |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
PMR1 |
YGL167C |
High affinity Ca2+/Mn2+ P-type ATPase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SSO2 |
YMR183C |
Plasma membrane t-SNARE |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ERG3 |
YLR056W |
C-5 sterol desaturase |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
CNA1 |
YLR433C |
Calcineurin A |
physical |
2 |
2 |
1 |
Reconstituted Complex, Biochemical Activity |
CMK2 |
YOL016C |
Calmodulin-dependent protein kinase |
genetic |
2 |
2 |
1 |
Synthetic Rescue, Phenotypic Suppression |
ERG27 |
YLR100W |
3-keto sterol reductase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
ALG2 |
YGL065C |
Mannosyltransferase in the N-linked glycosylation pathway |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
PHO2 |
YDL106C |
Homeobox transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
ADI1 |
YMR009W |
Acireductone dioxygenease involved in methionine salvage pathway |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
TMC1 |
YOR052C |
AN1-type zinc finger protein, effector of proteotoxic stress response |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
CMK2 |
YOL016C |
Calmodulin-dependent protein kinase |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
CIP1 |
YPL014W |
Cyclin-dependent kinase inhibitor |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
NCW2 |
YLR194C |
GPI-anchored protein involved in cell wall remodeling |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
CUP1-1 |
YHR053C |
Metallothionein |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
HSP30 |
YCR021C |
Negative regulator of the H(+)-ATPase Pma1p |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
RCR1 |
YBR005W |
Plasma membrane (PM) ubiquitin ligase-substrate adaptor |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
TPO2 |
YGR138C |
Polyamine transporter of the major facilitator superfamily |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
RCN2 |
YOR220W |
Protein of unknown function |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
DIA1 |
YMR316W |
Protein of unknown function |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
YLR162W |
YLR162W |
Protein of unknown function |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
YMR316C-A |
YMR316C-A |
Protein of unknown function |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
AIM17 |
YHL021C |
Protein of unknown function |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
YOR385W |
YOR385W |
Putative protein of unknown function |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
RRT15 |
YLR162W-A |
Putative protein of unknown function |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
YOL014W |
YOL014W |
Putative protein of unknown function |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
BTN2 |
YGR142W |
v-SNARE binding protein |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
genetic |
1 |
1 |
1 |
Negative Genetic |
ALA1 |
YOR335C |
Cytoplasmic and mitochondrial alanyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
CEG1 |
YGL130W |
Guanylyltransferase involved in mRNA 5' capping |
genetic |
1 |
1 |
1 |
Negative Genetic |
AVO1 |
YOL078W |
Component of the membrane-bound TORC2 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
BCY1 |
YIL033C |
Regulatory subunit of the cyclic AMP-dependent protein kinase (PKA) |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
BCK1 |
YJL095W |
MAPKKK acting in the protein kinase C signaling pathway |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
TAF7 |
YMR227C |
TFIID subunit (67 kDa) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SKN7 |
YHR206W |
Nuclear response regulator and transcription factor |
physical |
1 |
1 |
1 |
Reconstituted Complex |
SKN7 |
YHR206W |
Nuclear response regulator and transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
NMD5 |
YJR132W |
Karyopherin |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
MSN5 |
YDR335W |
Karyopherin |
physical |
1 |
1 |
1 |
Two-hybrid |
MSN5 |
YDR335W |
Karyopherin |
genetic |
1 |
1 |
1 |
Dosage Rescue |
SMT3 |
YDR510W |
Ubiquitin-like protein of the SUMO family |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
IME2 |
YJL106W |
Serine/threonine protein kinase involved in activation of meiosis |
physical |
1 |
1 |
1 |
Biochemical Activity |
KSP1 |
YHR082C |
Serine/threonine protein kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
MCK1 |
YNL307C |
Dual-specificity ser/thr and tyrosine protein kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
MCK1 |
YNL307C |
Dual-specificity ser/thr and tyrosine protein kinase |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
SKY1 |
YMR216C |
SR protein kinase (SRPK) |
physical |
1 |
1 |
1 |
Biochemical Activity |
STE20 |
YHL007C |
Cdc42p-activated signal transducing kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
SWE1 |
YJL187C |
Protein kinase that regulates the G2/M transition |
physical |
1 |
1 |
1 |
Biochemical Activity |
TOS3 |
YGL179C |
Protein kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
YCK1 |
YHR135C |
Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform |
physical |
1 |
1 |
1 |
Biochemical Activity |
YCK2 |
YNL154C |
Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform |
physical |
1 |
1 |
1 |
Biochemical Activity |
NNK1 |
YKL171W |
Protein kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
HEK2 |
YBL032W |
RNA binding protein involved in asymmetric localization of ASH1 mRNA |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
KDX1 |
YKL161C |
Protein kinase |
physical |
1 |
1 |
1 |
PCA |
SLT2 |
YHR030C |
Serine/threonine MAP kinase |
physical |
1 |
1 |
1 |
PCA |
CTK1 |
YKL139W |
Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) |
physical |
1 |
1 |
1 |
Reconstituted Complex |
CTK1 |
YKL139W |
Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) |
genetic |
1 |
1 |
1 |
Negative Genetic |
FRK1 |
YPL141C |
Protein kinase of unknown cellular role |
physical |
1 |
1 |
1 |
Reconstituted Complex |
GIN4 |
YDR507C |
Protein kinase involved in bud growth and assembly of the septin ring |
physical |
1 |
1 |
1 |
Reconstituted Complex |
ISR1 |
YPR106W |
Predicted protein kinase |
physical |
1 |
1 |
1 |
Reconstituted Complex |
KCC4 |
YCL024W |
Protein kinase of the bud neck involved in the septin checkpoint |
physical |
1 |
1 |
1 |
Reconstituted Complex |
KIN2 |
YLR096W |
S/T protein kinase |
physical |
1 |
1 |
1 |
Reconstituted Complex |
PKH2 |
YOL100W |
Serine/threonine protein kinase |
physical |
1 |
1 |
1 |
Reconstituted Complex |
YGK3 |
YOL128C |
Protein kinase related to mammalian GSK-3 glycogen synthase kinases |
physical |
1 |
1 |
1 |
Reconstituted Complex |
PHO80 |
YOL001W |
Cyclin |
physical |
1 |
1 |
1 |
Biochemical Activity |
HHF1 |
YBR009C |
Histone H4 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HHF2 |
YNL030W |
Histone H4 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PUF3 |
YLL013C |
Protein of the mitochondrial outer surface |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
SPT10 |
YJL127C |
Histone H3 acetylase with a role in transcriptional regulation |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SSB2 |
YNL209W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
1 |
1 |
1 |
Co-purification |
PUF2 |
YPR042C |
PUF family mRNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
ISW1 |
YBR245C |
ATPase subunit of imitation-switch (ISWI) class chromatin remodelers |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
MPT5 |
YGL178W |
mRNA-binding protein of the PUF family |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
PDE2 |
YOR360C |
High-affinity cyclic AMP phosphodiesterase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TFC6 |
YDR362C |
Subunit of RNA polymerase III transcription initiation factor complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YHC1 |
YLR298C |
Component of the U1 snRNP complex required for pre-mRNA splicing |
genetic |
1 |
1 |
1 |
Negative Genetic |
HAL5 |
YJL165C |
Snf1p-related nutrient-responsive protein kinase |
genetic |
1 |
1 |
1 |
Dosage Rescue |
VMA21 |
YGR105W |
Integral membrane protein required for V-ATPase function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
VOA1 |
YGR106C |
ER protein that functions in assembly of the V0 sector of V-ATPase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MSN2 |
YMR037C |
Stress-responsive transcriptional activator |
genetic |
1 |
1 |
1 |
Negative Genetic |
ELF1 |
YKL160W |
Transcription elongation factor with a conserved zinc finger domain |
genetic |
1 |
1 |
1 |
Negative Genetic |
ZAP1 |
YJL056C |
Zinc-regulated transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
MET32 |
YDR253C |
Zinc-finger DNA-binding transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
URE2 |
YNL229C |
Nitrogen catabolite repression transcriptional regulator |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPT3 |
YDR392W |
Subunit of the SAGA and SAGA-like transcriptional regulatory complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEF1 |
YBL066C |
Putative transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
FKH2 |
YNL068C |
Forkhead family transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
CSE2 |
YNR010W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SWI6 |
YLR182W |
Transcription cofactor |
genetic |
1 |
1 |
1 |
Negative Genetic |
TOD6 |
YBL054W |
PAC motif binding protein involved in rRNA and ribosome biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
MGA2 |
YIR033W |
ER membrane protein involved in regulation of OLE1 transcription |
genetic |
1 |
1 |
1 |
Negative Genetic |
SNT1 |
YCR033W |
Set3C histone deacetylase scaffold |
genetic |
1 |
1 |
1 |
Negative Genetic |
DOA1 |
YKL213C |
WD-repeat protein involved in ubiquitin-mediated protein degradation |
genetic |
1 |
1 |
1 |
Negative Genetic |
SAC3 |
YDR159W |
mRNA export factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEM1 |
YDR363W-A |
19S proteasome regulatory particle lid subcomplex component |
genetic |
1 |
1 |
1 |
Negative Genetic |
SUB1 |
YMR039C |
Transcriptional regulator |
genetic |
1 |
1 |
1 |
Negative Genetic |
SIF2 |
YBR103W |
WD40 repeat-containing subunit of Set3C histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
UBP3 |
YER151C |
Ubiquitin-specific protease that cleaves Ub-protein fusions |
genetic |
1 |
1 |
1 |
Negative Genetic |
RVS167 |
YDR388W |
Calmodulin-binding actin-associated protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
GYP6 |
YJL044C |
GTPase-activating protein (GAP) for yeast Rab family member Ypt6p |
genetic |
1 |
1 |
1 |
Positive Genetic |
HKR1 |
YDR420W |
Mucin family member that functions as an osmosensor in the HOG pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS27 |
YNR006W |
Endosomal protein that forms a complex with Hse1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
CSG2 |
YBR036C |
Endoplasmic reticulum membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
SNF4 |
YGL115W |
Activating gamma subunit of the AMP-activated Snf1p kinase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CTK3 |
YML112W |
Gamma subunit of C-terminal domain kinase I |
genetic |
1 |
1 |
1 |
Negative Genetic |
MET18 |
YIL128W |
Component of cytosolic iron-sulfur protein assembly (CIA) machinery |
genetic |
1 |
1 |
1 |
Negative Genetic |
RTG3 |
YBL103C |
bHLH/Zip transcription factor for retrograde (RTG) and TOR pathways |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPH2 |
YKL119C |
Integral membrane protein required for V-ATPase function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YPT6 |
YLR262C |
Rab family GTPase |
genetic |
1 |
1 |
1 |
Positive Genetic |
VMA11 |
YPL234C |
Vacuolar ATPase V0 domain subunit c' |
genetic |
1 |
1 |
1 |
Negative Genetic |
STE11 |
YLR362W |
Signal transducing MEK kinase |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
YPI1 |
YFR003C |
Regulatory subunit of the type I protein phosphatase (PP1) Glc7p |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
YAP1 |
YML007W |
Basic leucine zipper (bZIP) transcription factor |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PMP3 |
YDR276C |
Small plasma membrane protein |
genetic |
1 |
1 |
1 |
Dosage Rescue |
SMI1 |
YGR229C |
Protein involved in the regulation of cell wall synthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
KEX2 |
YNL238W |
Kexin, a subtilisin-like protease (proprotein convertase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
KRE1 |
YNL322C |
Cell wall glycoprotein involved in beta-glucan assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
GPI18 |
YBR004C |
Functional ortholog of human PIG-V |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS24 |
YKL041W |
One of four subunits of the ESCRT-III complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
NHX1 |
YDR456W |
Na+/H+ and K+/H+ exchanger |
genetic |
1 |
1 |
1 |
Negative Genetic |
GYP1 |
YOR070C |
Cis-golgi GTPase-activating protein (GAP) for yeast Rabs |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS5 |
YOR069W |
Nexin-1 homolog |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS17 |
YOR132W |
Subunit of the membrane-associated retromer complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SRO7 |
YPR032W |
Effector of Rab GTPase Sec4p |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERG26 |
YGL001C |
C-3 sterol dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ELO3 |
YLR372W |
Elongase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RSP5 |
YER125W |
NEDD4 family E3 ubiquitin ligase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
ORM1 |
YGR038W |
Protein that mediates sphingolipid homeostasis |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
ORM2 |
YLR350W |
Protein that mediates sphingolipid homeostasis |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
GPI11 |
YDR302W |
ER membrane protein involved in a late step of GPI anchor assembly |
genetic |
1 |
1 |
1 |
Positive Genetic |
GPI16 |
YHR188C |
Subunit of the glycosylphosphatidylinositol transamidase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
GPI13 |
YLL031C |
ER membrane localized phosphoryltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
RFC2 |
YJR068W |
Subunit of heteropentameric Replication factor C (RF-C) |
genetic |
1 |
1 |
1 |
Positive Genetic |
DFR1 |
YOR236W |
Dihydrofolate reductase involved in tetrahydrofolate biosynthesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
ICS2 |
YBR157C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
DST1 |
YGL043W |
General transcription elongation factor TFIIS |
genetic |
1 |
1 |
1 |
Positive Genetic |
YJR084W |
YJR084W |
Protein that forms a complex with Thp3p |
genetic |
1 |
1 |
1 |
Positive Genetic |
RAD14 |
YMR201C |
Subunit of Nucleotide Excision Repair Factor 1 (NEF1) |
genetic |
1 |
1 |
1 |
Positive Genetic |
RFT1 |
YBL020W |
Membrane protein required for translocation of Man5GlcNac2-PP-Dol |
genetic |
1 |
1 |
1 |
Negative Genetic |
POL5 |
YEL055C |
Protein involved in 60S assembly and pre-40S AFs recycling |
genetic |
1 |
1 |
1 |
Negative Genetic |
PMI40 |
YER003C |
Mannose-6-phosphate isomerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRP22 |
YER013W |
DEAH-box RNA-dependent ATPase/ATP-dependent RNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
VRG4 |
YGL225W |
Golgi GDP-mannose transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
STU2 |
YLR045C |
Microtubule polymerase of the XMAP215/Dis1 family |
genetic |
1 |
1 |
1 |
Negative Genetic |
FAS2 |
YPL231W |
Alpha subunit of fatty acid synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC17 |
YBL050W |
Alpha-SNAP cochaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
MED8 |
YBR193C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
TSC13 |
YDL015C |
Enoyl reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
TIM22 |
YDL217C |
Essential core component of mitochondrial TIM22 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
MOB2 |
YFL034C-B |
Activator of Cbk1p kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
NBP35 |
YGL091C |
Essential cytoplasmic iron-sulfur cluster binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
DAM1 |
YGR113W |
Essential subunit of the Dam1 complex (aka DASH complex) |
genetic |
1 |
1 |
1 |
Negative Genetic |
MES1 |
YGR264C |
Methionyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MED6 |
YHR058C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
UTP9 |
YHR196W |
Nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
NUP192 |
YJL039C |
Essential subunit of inner ring of nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
GWT1 |
YJL091C |
Protein involved in the inositol acylation of GlcN-PI |
genetic |
1 |
1 |
1 |
Negative Genetic |
POL31 |
YJR006W |
Subunit of DNA polymerase delta (polymerase III) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SSC1 |
YJR045C |
Hsp70 family ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
GSP1 |
YLR293C |
Ran GTPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RNA1 |
YMR235C |
GTPase activating protein (GAP) for Gsp1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
MGE1 |
YOR232W |
Mitochondrial matrix cochaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
GCD1 |
YOR260W |
Gamma subunit of the translation initiation factor eIF2B |
genetic |
1 |
1 |
1 |
Negative Genetic |
NIP7 |
YPL211W |
Nucleolar protein required for 60S ribosome subunit biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC23 |
YPR181C |
GTPase-activating protein, stimulates the GTPase activity of Sar1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
YBR196C-A |
YBR196C-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
IMG1 |
YCR046C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
OST4 |
YDL232W |
Subunit of the oligosaccharyltransferase complex of the ER lumen |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS52 |
YDR484W |
Component of the GARP (Golgi-associated retrograde protein) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
YER079W |
YER079W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
STM1 |
YLR150W |
Protein required for optimal translation under nutrient stress |
genetic |
1 |
1 |
1 |
Negative Genetic |
VAN1 |
YML115C |
Component of the mannan polymerase I |
genetic |
1 |
1 |
1 |
Negative Genetic |
PAH1 |
YMR165C |
Mg2+-dependent phosphatidate (PA) phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PEX5 |
YDR244W |
Peroxisomal membrane signal receptor for peroxisomal matrix proteins |
genetic |
1 |
1 |
1 |
Negative Genetic |
MNN10 |
YDR245W |
Subunit of a Golgi mannosyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
MIC19 |
YFR011C |
Component of the MICOS complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PHB2 |
YGR231C |
Subunit of the prohibitin complex (Phb1p-Phb2p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
STB5 |
YHR178W |
Transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
YJR011C |
YJR011C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPE1 |
YKL184W |
Ornithine decarboxylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MIC60 |
YKR016W |
Component of the MICOS complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRPL39 |
YML009C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
SCS7 |
YMR272C |
Sphingolipid alpha-hydroxylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
HMI1 |
YOL095C |
Mitochondrial inner membrane localized ATP-dependent DNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PET127 |
YOR017W |
Protein with a role in 5'-end processing of mitochondrial RNAs |
genetic |
1 |
1 |
1 |
Negative Genetic |
SYC1 |
YOR179C |
Subunit of the APT subcomplex of cleavage and polyadenylation factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
LIP5 |
YOR196C |
Protein involved in biosynthesis of the coenzyme lipoic acid |
genetic |
1 |
1 |
1 |
Negative Genetic |
NEW1 |
YPL226W |
Translation termination and ribosome biogenesis factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
QCR2 |
YPR191W |
Subunit 2 of ubiquinol cytochrome-c reductase (Complex III) |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERG24 |
YNL280C |
C-14 sterol reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MON2 |
YNL297C |
Protein with a role in endocytosis and vacuole integrity |
genetic |
1 |
1 |
1 |
Negative Genetic |
RFM1 |
YOR279C |
Component of the Sum1p-Rfm1p-Hst1p complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
YPL039W |
YPL039W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
GRX6 |
YDL010W |
Cis-Golgi localized monothiol glutaredoxin, binds Fe-S cluster |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
YPK1 |
YKL126W |
S/T protein kinase |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
VPS13 |
YLL040C |
Lipid transport protein involved in prospore membrane morphogenesis |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
AKL1 |
YBR059C |
Ser/Thr protein kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
ADR1 |
YDR216W |
Carbon source-responsive zinc-finger transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
CAF20 |
YOR276W |
Phosphoprotein of the mRNA cap-binding complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
ADO1 |
YJR105W |
Adenosine kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
CMP2 |
YML057W |
Calcineurin A |
physical |
1 |
1 |
1 |
Reconstituted Complex |
CMK1 |
YFR014C |
Calmodulin-dependent protein kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
CHS1 |
YNL192W |
Chitin synthase I |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
CLB2 |
YPR119W |
B-type cyclin involved in cell cycle progression |
genetic |
1 |
1 |
1 |
Dosage Lethality |
ATG1 |
YGL180W |
Protein serine/threonine kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
BOS1 |
YLR078C |
v-SNARE (vesicle specific SNAP receptor) |
genetic |
1 |
1 |
1 |
Negative Genetic |
BRE5 |
YNR051C |
Ubiquitin protease cofactor |
genetic |
1 |
1 |
1 |
Negative Genetic |
CBF1 |
YJR060W |
Basic helix-loop-helix (bHLH) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
CLC1 |
YGR167W |
Clathrin light chain |
genetic |
1 |
1 |
1 |
Negative Genetic |
CLA4 |
YNL298W |
Cdc42p-activated signal transducing kinase |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
CFD1 |
YIL003W |
Highly conserved iron-sulfur cluster binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
ADE16 |
YLR028C |
Enzyme of 'de novo' purine biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
BRL1 |
YHR036W |
Essential nuclear envelope/ER integral membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
APJ1 |
YNL077W |
Hsp40 chaperone with a role in SUMO-mediated protein degradation |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ARV1 |
YLR242C |
Cortical ER protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
ALG14 |
YBR070C |
Component of UDP-GlcNAc transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
COX7 |
YMR256C |
Subunit VII of cytochrome c oxidase (Complex IV) |
genetic |
1 |
1 |
1 |
Negative Genetic |
AVL9 |
YLR114C |
Conserved protein involved in exocytic transport from the Golgi |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC1 |
YDR182W |
Putative mannose-ethanolamine phosphate phosphodiesterase |
genetic |
1 |
1 |
1 |
Negative Genetic |