Standard name Systematic name Name description Description
VOA1 YGR106C ER protein that functions in assembly of the V0 sector of V-ATPase ER protein that functions in assembly of the V0 sector of V-ATPase; functions with other assembly factors; null mutation enhances the vacuolar ATPase (V-ATPase) deficiency of a vma21 mutant impaired in endoplasmic reticulum (ER) retrieval
Visualize the interactome of VOA1
Links to external databases:
SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Golgi NaN 0.082 0.058
Nucleolus NaN 0.096 0.094
Nucleus NaN 0.096 NaN
Vac/Vac Memb NaN 0.877 0.783
Mito NaN NaN 0.087
Nuc Periphery NaN NaN 0.109

GFP localization & abundance

GFP localization GFP abundance
no data no data

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
VOA1 0 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
FKH1 YIL131C Forkhead family transcription factor regulation 3 2 3 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments
SEC66 YBR171W Non-essential subunit of Sec63 complex genetic 3 2 2 Positive Genetic, Positive Genetic, Synthetic Growth Defect
VMA21 YGR105W Integral membrane protein required for V-ATPase function genetic 3 2 2 Synthetic Growth Defect, Synthetic Growth Defect, Phenotypic Enhancement
FKH2 YNL068C Forkhead family transcription factor regulation 2 2 2 chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments
BCK1 YJL095W MAPKKK acting in the protein kinase C signaling pathway genetic 2 2 2 Synthetic Growth Defect, Dosage Growth Defect
VMA21 YGR105W Integral membrane protein required for V-ATPase function physical 2 2 2 PCA, Affinity Capture-MS
PKR1 YMR123W V-ATPase assembly factor genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
VMA13 YPR036W Subunit H of the V1 peripheral membrane domain of V-ATPase physical 2 1 2 PCA, PCA
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes genetic 2 1 1 Dosage Lethality, Dosage Lethality
BFR1 YOR198C Component of mRNP complexes associated with polyribosomes genetic 2 1 1 Positive Genetic, Positive Genetic
FRT1 YOR324C Tail-anchored ER membrane protein of unknown function genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
TSC3 YBR058C-A Protein that stimulates the activity of serine palmitoyltransferase genetic 2 1 1 Negative Genetic, Negative Genetic
GCR1 YPL075W Transcriptional activator of genes involved in glycolysis regulation 1 1 1 DNA to cDNA expression microarray evidence
SPT20 YOL148C Subunit of the SAGA transcriptional regulatory complex regulation 1 1 1 DNA to cDNA expression microarray evidence
SIN4 YNL236W Subunit of the RNA polymerase II mediator complex regulation 1 1 1 DNA to cDNA expression microarray evidence
TFC7 YOR110W RNA pol III transcription initiation factor complex (TFIIIC) subunit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CST6 YIL036W Basic leucine zipper (bZIP) transcription factor from ATF/CREB family regulation 1 1 1 DNA to cDNA expression microarray evidence
CHD1 YER164W Chromatin remodeler that regulates various aspects of transcription genetic 1 1 1 Synthetic Growth Defect
LEO1 YOR123C Component of the Paf1 complex genetic 1 1 1 Synthetic Growth Defect
CKA1 YIL035C Alpha catalytic subunit of casein kinase 2 (CK2) genetic 1 1 1 Synthetic Growth Defect
CKB1 YGL019W Beta regulatory subunit of casein kinase 2 (CK2) genetic 1 1 1 Synthetic Growth Defect
CKB2 YOR039W Beta' regulatory subunit of casein kinase 2 (CK2) genetic 1 1 1 Synthetic Growth Defect
IKI3 YLR384C Subunit of Elongator complex genetic 1 1 1 Synthetic Growth Defect
ESA1 YOR244W Catalytic subunit of the histone acetyltransferase complex (NuA4) physical 1 1 1 Biochemical Activity
EAF1 YDR359C Component of the NuA4 histone acetyltransferase complex genetic 1 1 1 Synthetic Growth Defect
BRE1 YDL074C E3 ubiquitin ligase genetic 1 1 1 Synthetic Growth Defect
ARL1 YBR164C Soluble GTPase with a role in regulation of membrane traffic genetic 1 1 1 Synthetic Growth Defect
KES1 YPL145C Sterol/phosphatidylinositol-4-phosphate (PI(4)P) exchanger genetic 1 1 1 Synthetic Growth Defect
BMH1 YER177W 14-3-3 protein, major isoform genetic 1 1 1 Synthetic Growth Defect
DBP7 YKR024C Putative ATP-dependent RNA helicase of the DEAD-box family genetic 1 1 1 Synthetic Growth Defect
MDM20 YOL076W Non-catalytic subunit of the NatB N-terminal acetyltransferase genetic 1 1 1 Synthetic Growth Defect
SAP155 YFR040W Protein required for function of the Sit4p protein phosphatase genetic 1 1 1 Synthetic Growth Defect
LSM1 YJL124C Lsm (Like Sm) protein genetic 1 1 1 Synthetic Growth Defect
RPS4B YHR203C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Synthetic Growth Defect
NPL3 YDR432W RNA-binding protein genetic 1 1 1 Synthetic Growth Defect
RPA34 YJL148W RNA polymerase I subunit A34.5 genetic 1 1 1 Synthetic Growth Defect
STO1 YMR125W Large subunit of the nuclear mRNA cap-binding protein complex genetic 1 1 1 Synthetic Growth Defect
SIN4 YNL236W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Synthetic Growth Defect
SRB2 YHR041C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Synthetic Growth Defect
RGR1 YLR071C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
DST1 YGL043W General transcription elongation factor TFIIS genetic 1 1 1 Synthetic Growth Defect
CEX1 YOR112W Component of nuclear aminoacylation-dependent tRNA export pathway genetic 1 1 1 Synthetic Growth Defect
UBP6 YFR010W Ubiquitin-specific protease genetic 1 1 1 Synthetic Growth Defect
HCR1 YLR192C eIF3j component of translation initiation factor 3 (eIF3) genetic 1 1 1 Synthetic Growth Defect
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 1 1 1 Negative Genetic
RBG2 YGR173W Protein with a role in translation genetic 1 1 1 Synthetic Growth Defect
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex genetic 1 1 1 Synthetic Growth Defect
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
NAM7 YMR080C ATP-dependent RNA helicase of the SFI superfamily genetic 1 1 1 Synthetic Growth Defect
TSR2 YLR435W Protein with a potential role in pre-rRNA processing genetic 1 1 1 Synthetic Growth Defect
EFT2 YDR385W Elongation factor 2 (EF-2), also encoded by EFT1 genetic 1 1 1 Synthetic Growth Defect
HGH1 YGR187C Chaperone protein for translation factor eEF2 genetic 1 1 1 Synthetic Growth Defect
APL5 YPL195W Delta adaptin-like subunit of the clathrin associated protein complex genetic 1 1 1 Synthetic Growth Defect
APL6 YGR261C Beta3-like subunit of the yeast AP-3 complex genetic 1 1 1 Synthetic Growth Defect
ARO1 YDR127W Pentafunctional arom protein genetic 1 1 1 Synthetic Growth Defect
ASF1 YJL115W Nucleosome assembly factor genetic 1 1 1 Synthetic Growth Defect
BDF1 YLR399C BET family transcriptional regulator genetic 1 1 1 Synthetic Growth Defect
ASC1 YMR116C G-protein beta subunit and guanine dissociation inhibitor for Gpa2p genetic 1 1 1 Synthetic Growth Defect
BEM2 YER155C Rho GTPase activating protein (RhoGAP) genetic 1 1 1 Synthetic Growth Defect
BUD14 YAR014C Protein involved in bud-site selection genetic 1 1 1 Synthetic Growth Defect
CTF18 YMR078C Subunit of a complex with Ctf8p genetic 1 1 1 Synthetic Growth Defect
CTK1 YKL139W Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) genetic 1 1 1 Synthetic Growth Defect
DOA1 YKL213C WD-repeat protein involved in ubiquitin-mediated protein degradation genetic 1 1 1 Synthetic Growth Defect
ELP2 YGR200C Subunit of Elongator complex genetic 1 1 1 Synthetic Growth Defect
EAF3 YPR023C Component of the Rpd3S histone deacetylase complex genetic 1 1 1 Synthetic Growth Defect
FKS1 YLR342W Catalytic subunit of 1,3-beta-D-glucan synthase genetic 1 1 1 Synthetic Growth Defect
GCN1 YGL195W Positive regulator of the Gcn2p kinase activity genetic 1 1 1 Synthetic Growth Defect
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
COG8 YML071C Component of the conserved oligomeric Golgi complex genetic 1 1 1 Synthetic Growth Defect
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers genetic 1 1 1 Synthetic Growth Defect
ENO2 YHR174W Enolase II, a phosphopyruvate hydratase physical 1 1 1 Affinity Capture-MS
MDM10 YAL010C Subunit of both the ERMES and the SAM complex genetic 1 1 1 Synthetic Growth Defect
GAL11 YOL051W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Synthetic Growth Defect
MRPL35 YDR322W Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Synthetic Growth Defect
MGM101 YJR144W Protein with a role in mitochondrial DNA recombinational repair genetic 1 1 1 Synthetic Growth Defect
GIN4 YDR507C Protein kinase involved in bud growth and assembly of the septin ring genetic 1 1 1 Negative Genetic
HTZ1 YOL012C Histone variant H2AZ genetic 1 1 1 Synthetic Growth Defect
APM1 YPL259C Mu1-like medium subunit of the AP-1 complex genetic 1 1 1 Synthetic Growth Defect
LPD1 YFL018C Dihydrolipoamide dehydrogenase genetic 1 1 1 Synthetic Growth Defect
PDA1 YER178W E1 alpha subunit of the pyruvate dehydrogenase (PDH) complex genetic 1 1 1 Synthetic Growth Defect
PFK1 YGR240C Alpha subunit of heterooctameric phosphofructokinase genetic 1 1 1 Synthetic Growth Defect
IDH2 YOR136W Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase genetic 1 1 1 Synthetic Growth Defect
POP2 YNR052C Subunit of Ccr4-Not complex that mediates 3' to 5' mRNA deadenylation genetic 1 1 1 Synthetic Growth Defect
HSP82 YPL240C Hsp90 chaperone genetic 1 1 1 Synthetic Growth Defect
MET18 YIL128W Component of cytosolic iron-sulfur protein assembly (CIA) machinery genetic 1 1 1 Synthetic Growth Defect
ILV1 YER086W Threonine deaminase, catalyzes first step in isoleucine biosynthesis genetic 1 1 1 Synthetic Growth Defect
PGD1 YGL025C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Synthetic Growth Defect
RPL2A YFR031C-A Ribosomal 60S subunit protein L2A genetic 1 1 1 Synthetic Growth Defect
MAF1 YDR005C Highly conserved negative regulator of RNA polymerase III genetic 1 1 1 Synthetic Growth Defect
RTS1 YOR014W B-type regulatory subunit of protein phosphatase 2A (PP2A) genetic 1 1 1 Synthetic Growth Defect
OPI1 YHL020C Transcriptional regulator of a variety of genes genetic 1 1 1 Synthetic Growth Defect
SCS2 YER120W Integral ER membrane protein, regulates phospholipid metabolism genetic 1 1 1 Synthetic Growth Defect
PIL1 YGR086C Eisosome core component genetic 1 1 1 Synthetic Growth Defect
RSA4 YCR072C Ribosomal large subunit (60S) assembly factor genetic 1 1 1 Negative Genetic
MNN10 YDR245W Subunit of a Golgi mannosyltransferase complex genetic 1 1 1 Synthetic Growth Defect
SET2 YJL168C Histone methyltransferase with a role in transcriptional elongation genetic 1 1 1 Synthetic Growth Defect
SLA1 YBL007C Cytoskeletal protein binding protein genetic 1 1 1 Synthetic Growth Defect
LSB3 YFR024C-A Protein containing a C-terminal SH3 domain genetic 1 1 1 Synthetic Growth Defect
SNF1 YDR477W AMP-activated S/T protein kinase genetic 1 1 1 Synthetic Growth Defect
SNF2 YOR290C Catalytic subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Synthetic Growth Defect
SPE3 YPR069C Spermidine synthase genetic 1 1 1 Synthetic Growth Defect
SSE1 YPL106C ATPase component of heat shock protein Hsp90 chaperone complex genetic 1 1 1 Synthetic Growth Defect
SRB8 YCR081W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Synthetic Growth Defect
TAF1 YGR274C TFIID subunit, involved in RNA pol II transcription initiation genetic 1 1 1 Synthetic Lethality
PTC1 YDL006W Type 2C protein phosphatase (PP2C) genetic 1 1 1 Dosage Rescue
SBP1 YHL034C Protein that binds eIF4G and has a role in repression of translation physical 1 1 1 Affinity Capture-RNA
SBP1 YHL034C Protein that binds eIF4G and has a role in repression of translation genetic 1 1 1 Synthetic Growth Defect
MGA2 YIR033W ER membrane protein involved in regulation of OLE1 transcription genetic 1 1 1 Synthetic Growth Defect
SCJ1 YMR214W One of several homologs of bacterial chaperone DnaJ genetic 1 1 1 Synthetic Growth Defect
MKS1 YNL076W Pleiotropic negative transcriptional regulator genetic 1 1 1 Synthetic Growth Defect
TPS1 YBR126C Synthase subunit of trehalose-6-P synthase/phosphatase complex genetic 1 1 1 Synthetic Growth Defect
TRP2 YER090W Anthranilate synthase genetic 1 1 1 Synthetic Growth Defect
UBP15 YMR304W Ubiquitin-specific protease involved in protein deubiquitination genetic 1 1 1 Synthetic Growth Defect
RAV1 YJR033C Subunit of RAVE complex (Rav1p, Rav2p, Skp1p) genetic 1 1 1 Synthetic Growth Defect
VMA6 YLR447C Subunit d of the V0 integral membrane domain of V-ATPase physical 1 1 1 PCA
VMA7 YGR020C Subunit F of the V1 peripheral membrane domain of V-ATPase physical 1 1 1 PCA
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p genetic 1 1 1 Synthetic Growth Defect
DRS2 YAL026C Trans-golgi network aminophospholipid translocase (flippase) genetic 1 1 1 Synthetic Growth Defect
BRE2 YLR015W Subunit of COMPASS (Set1C) complex genetic 1 1 1 Synthetic Growth Defect
PIN4 YBL051C Protein involved in G2/M phase progression and response to DNA damage genetic 1 1 1 Synthetic Growth Defect
GET3 YDL100C Guanine nucleotide exchange factor for Gpa1p genetic 1 1 1 Synthetic Growth Defect
CRZ1 YNL027W Transcription factor, activates transcription of stress response genes genetic 1 1 1 Synthetic Growth Defect
GAS1 YMR307W Beta-1,3-glucanosyltransferase required for cell wall assembly genetic 1 1 1 Synthetic Growth Defect
FET4 YMR319C Low-affinity Fe(II) transporter of the plasma membrane genetic 1 1 1 Synthetic Growth Defect
PHO85 YPL031C Cyclin-dependent kinase genetic 1 1 1 Synthetic Growth Defect
ADO1 YJR105W Adenosine kinase genetic 1 1 1 Synthetic Growth Defect
ARF1 YDL192W ADP-ribosylation factor genetic 1 1 1 Synthetic Growth Defect
CNB1 YKL190W Calcineurin B genetic 1 1 1 Synthetic Growth Defect
PBS2 YJL128C MAP kinase kinase of the HOG signaling pathway genetic 1 1 1 Synthetic Growth Defect
GSF2 YML048W Endoplasmic reticulum (ER) localized integral membrane protein genetic 1 1 1 Synthetic Growth Defect
FET3 YMR058W Ferro-O2-oxidoreductase genetic 1 1 1 Synthetic Growth Defect
RVS161 YCR009C Amphiphysin-like lipid raft protein genetic 1 1 1 Synthetic Growth Defect
FYV10 YIL097W Subunit of GID complex genetic 1 1 1 Synthetic Growth Defect
APM3 YBR288C Mu3-like subunit of the clathrin associated protein complex (AP-3) genetic 1 1 1 Synthetic Growth Defect
AAT2 YLR027C Cytosolic aspartate aminotransferase involved in nitrogen metabolism genetic 1 1 1 Synthetic Growth Defect
GET1 YGL020C Subunit of the GET complex genetic 1 1 1 Synthetic Growth Defect
GET2 YER083C Subunit of the GET complex genetic 1 1 1 Synthetic Growth Defect
SLX5 YDL013W Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex genetic 1 1 1 Synthetic Growth Defect
PHO81 YGR233C Cyclin-dependent kinase (CDK) inhibitor genetic 1 1 1 Synthetic Growth Defect
PCT1 YGR202C Cholinephosphate cytidylyltransferase genetic 1 1 1 Synthetic Growth Defect
SOD2 YHR008C Mitochondrial manganese superoxide dismutase genetic 1 1 1 Synthetic Growth Defect
ELM1 YKL048C Serine/threonine protein kinase genetic 1 1 1 Synthetic Growth Defect
GPA2 YER020W Nucleotide binding alpha subunit of the heterotrimeric G protein genetic 1 1 1 Synthetic Growth Defect
CAT5 YOR125C Protein required for ubiquinone (Coenzyme Q) biosynthesis genetic 1 1 1 Synthetic Growth Defect
SHP1 YBL058W UBX domain-containing substrate adaptor for Cdc48p genetic 1 1 1 Synthetic Growth Defect
UFD2 YDL190C Ubiquitin (Ub) chain assembly factor (E4) genetic 1 1 1 Synthetic Growth Defect
RNA1 YMR235C GTPase activating protein (GAP) for Gsp1p genetic 1 1 1 Negative Genetic
ERG6 YML008C Delta(24)-sterol C-methyltransferase genetic 1 1 1 Synthetic Growth Defect
GIS4 YML006C CAAX box containing protein of unknown function genetic 1 1 1 Synthetic Growth Defect
DIA2 YOR080W Origin-binding F-box protein genetic 1 1 1 Synthetic Growth Defect
CTF4 YPR135W Chromatin-associated protein genetic 1 1 1 Synthetic Growth Defect
BEM4 YPL161C Protein involved in establishment of cell polarity and bud emergence genetic 1 1 1 Synthetic Growth Defect
BCK2 YER167W Serine/threonine-rich protein involved in PKC1 signaling pathway genetic 1 1 1 Synthetic Growth Defect
HAL5 YJL165C Snf1p-related nutrient-responsive protein kinase genetic 1 1 1 Synthetic Growth Defect
PCL6 YER059W Pho85p cyclin of the Pho80p subfamily genetic 1 1 1 Synthetic Growth Defect
RTT103 YDR289C Protein involved in transcription termination by RNA polymerase II genetic 1 1 1 Synthetic Growth Defect
MCK1 YNL307C Dual-specificity ser/thr and tyrosine protein kinase genetic 1 1 1 Synthetic Growth Defect
TEF4 YKL081W Gamma subunit of translational elongation factor eEF1B genetic 1 1 1 Synthetic Growth Defect
UBC7 YMR022W Ubiquitin conjugating enzyme genetic 1 1 1 Synthetic Growth Defect
DBF2 YGR092W Ser/Thr kinase involved in transcription and stress response genetic 1 1 1 Synthetic Growth Defect
DUF1 YOL087C Ubiquitin-binding protein of unknown function genetic 1 1 1 Synthetic Growth Defect
GCR2 YNL199C Transcriptional activator of genes involved in glycolysis genetic 1 1 1 Synthetic Growth Defect
APE3 YBR286W Vacuolar aminopeptidase Y genetic 1 1 1 Synthetic Growth Defect
HFL1 YKR051W Vacuole membrane protein that interacts with Atg8p genetic 1 1 1 Synthetic Growth Defect
PHO86 YJL117W Endoplasmic reticulum (ER) resident protein genetic 1 1 1 Synthetic Growth Defect
NUP133 YKR082W Subunit of Nup84p subcomplex of nuclear pore complex (NPC) genetic 1 1 1 Synthetic Growth Defect
SNF4 YGL115W Activating gamma subunit of the AMP-activated Snf1p kinase complex genetic 1 1 1 Synthetic Growth Defect
MMS22 YLR320W Subunit of E3 ubiquitin ligase complex involved in replication repair genetic 1 1 1 Synthetic Growth Defect
ESS1 YJR017C Peptidylprolyl-cis/trans-isomerase (PPIase) genetic 1 1 1 Synthetic Growth Defect
NBP2 YDR162C Protein involved in the HOG (high osmolarity glycerol) pathway genetic 1 1 1 Synthetic Growth Defect
SKA1 YKL023W SKI complex-associated protein genetic 1 1 1 Synthetic Growth Defect
UBA4 YHR111W E1-like protein that activates Urm1p before urmylation genetic 1 1 1 Synthetic Growth Defect
CPR2 YHR057C Peptidyl-prolyl cis-trans isomerase (cyclophilin) genetic 1 1 1 Synthetic Growth Defect
FUI1 YBL042C High affinity uridine permease, localizes to the plasma membrane genetic 1 1 1 Synthetic Growth Defect
FIG1 YBR040W Integral membrane protein required for efficient mating genetic 1 1 1 Negative Genetic
TRS85 YDR108W Component of transport protein particle (TRAPP) complex III genetic 1 1 1 Synthetic Growth Defect
SMT3 YDR510W Ubiquitin-like protein of the SUMO family genetic 1 1 1 Negative Genetic
INO2 YDR123C Transcription factor genetic 1 1 1 Synthetic Growth Defect
MSN5 YDR335W Karyopherin genetic 1 1 1 Synthetic Growth Defect
RIM101 YHL027W Cys2His2 zinc-finger transcriptional repressor genetic 1 1 1 Synthetic Growth Defect
ATG27 YJL178C Type I membrane protein involved in autophagy and the Cvt pathway genetic 1 1 1 Synthetic Growth Defect
PET191 YJR034W Protein required for assembly of cytochrome c oxidase genetic 1 1 1 Synthetic Growth Defect
TOP1 YOL006C Topoisomerase I genetic 1 1 1 Synthetic Growth Defect
VAM7 YGL212W Vacuolar SNARE protein genetic 1 1 1 Synthetic Growth Defect
KTI12 YKL110C Protein that plays a role in modification of tRNA wobble nucleosides genetic 1 1 1 Synthetic Growth Defect
URE2 YNL229C Nitrogen catabolite repression transcriptional regulator genetic 1 1 1 Synthetic Growth Defect
ELP6 YMR312W Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex genetic 1 1 1 Synthetic Growth Defect
BLI1 YKL061W Subunit of the BLOC-1 complex involved in endosomal maturation genetic 1 1 1 Synthetic Growth Defect
NST1 YNL091W Translational inhibitor and suppressor of proteasome-assembly defects genetic 1 1 1 Synthetic Growth Defect
APC11 YDL008W Catalytic core subunit, Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Negative Genetic
COG7 YGL005C Component of the conserved oligomeric Golgi complex genetic 1 1 1 Synthetic Growth Defect
COG6 YNL041C Component of the conserved oligomeric Golgi complex genetic 1 1 1 Synthetic Growth Defect
COG5 YNL051W Component of the conserved oligomeric Golgi complex genetic 1 1 1 Synthetic Growth Defect
ELP3 YPL086C Subunit of Elongator complex genetic 1 1 1 Synthetic Growth Defect
ELP4 YPL101W Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex genetic 1 1 1 Synthetic Growth Defect
RPL9A YGL147C Ribosomal 60S subunit protein L9A genetic 1 1 1 Synthetic Growth Defect
RPS24A YER074W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Synthetic Growth Defect
RTG1 YOL067C Transcription factor (bHLH) involved in interorganelle communication genetic 1 1 1 Synthetic Growth Defect
SPT4 YGR063C Spt4p/5p (DSIF) transcription elongation factor complex subunit genetic 1 1 1 Synthetic Growth Defect
SAC3 YDR159W mRNA export factor genetic 1 1 1 Synthetic Growth Defect
SPT3 YDR392W Subunit of the SAGA and SAGA-like transcriptional regulatory complexes genetic 1 1 1 Synthetic Growth Defect
ARP6 YLR085C Actin-related protein that binds nucleosomes genetic 1 1 1 Synthetic Growth Defect
SWR1 YDR334W Swi2/Snf2-related ATPase genetic 1 1 1 Synthetic Growth Defect
SWC5 YBR231C Component of the SWR1 complex genetic 1 1 1 Synthetic Growth Defect
DAL81 YIR023W Positive regulator of genes in multiple nitrogen degradation pathways genetic 1 1 1 Synthetic Growth Defect
SNF11 YDR073W Subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Synthetic Growth Defect
SNF6 YHL025W Subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Synthetic Growth Defect
CBF1 YJR060W Basic helix-loop-helix (bHLH) protein genetic 1 1 1 Synthetic Growth Defect
SWI6 YLR182W Transcription cofactor genetic 1 1 1 Synthetic Growth Defect
PHO4 YFR034C Basic helix-loop-helix (bHLH) transcription factor of the myc-family genetic 1 1 1 Synthetic Growth Defect
RTG3 YBL103C bHLH/Zip transcription factor for retrograde (RTG) and TOR pathways genetic 1 1 1 Synthetic Growth Defect
RPS11A YDR025W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Synthetic Growth Defect
RPS11B YBR048W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Synthetic Growth Defect
RIF1 YBR275C Protein involved in control of DNA replication genetic 1 1 1 Synthetic Growth Defect
ATG8 YBL078C Ub-like protein genetic 1 1 1 Synthetic Growth Defect
BFR1 YOR198C Component of mRNP complexes associated with polyribosomes physical 1 1 1 Affinity Capture-RNA
ELO3 YLR372W Elongase genetic 1 1 1 Synthetic Growth Defect
IOC2 YLR095C Subunit of the Isw1b complex genetic 1 1 1 Synthetic Growth Defect
KAR3 YPR141C Minus-end-directed microtubule motor genetic 1 1 1 Synthetic Growth Defect
ATS1 YAL020C Protein required for modification of wobble nucleosides in tRNA genetic 1 1 1 Synthetic Growth Defect
OST3 YOR085W Gamma subunit of the oligosaccharyltransferase complex of the ER lumen genetic 1 1 1 Synthetic Growth Defect
PHO80 YOL001W Cyclin genetic 1 1 1 Synthetic Growth Defect
RTG2 YGL252C Sensor of mitochondrial dysfunction genetic 1 1 1 Synthetic Growth Defect
ERV41 YML067C Protein localized to COPII-coated vesicles genetic 1 1 1 Negative Genetic
SEC22 YLR268W R-SNARE protein genetic 1 1 1 Synthetic Growth Defect
SKN7 YHR206W Nuclear response regulator and transcription factor genetic 1 1 1 Synthetic Growth Defect
RCY1 YJL204C F-box protein involved in recycling endocytosed proteins genetic 1 1 1 Synthetic Growth Defect
RAV2 YDR202C Subunit of RAVE complex (Rav1p, Rav2p, Skp1p) genetic 1 1 1 Synthetic Growth Defect
SRO7 YPR032W Effector of Rab GTPase Sec4p genetic 1 1 1 Synthetic Growth Defect
SSA1 YAL005C ATPase involved in protein folding and NLS-directed nuclear transport physical 1 1 1 Affinity Capture-MS
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p) genetic 1 1 1 Synthetic Growth Defect
NMD2 YHR077C Protein involved in the nonsense-mediated mRNA decay (NMD) pathway genetic 1 1 1 Synthetic Growth Defect
FIG4 YNL325C Phosphatidylinositol 3,5-bisphosphate (PtdIns[3,5]P) phosphatase genetic 1 1 1 Synthetic Growth Defect
SRN2 YLR119W Component of the ESCRT-I complex genetic 1 1 1 Synthetic Growth Defect
PEP8 YJL053W Vacuolar protein component of the retromer genetic 1 1 1 Synthetic Growth Defect
CCZ1 YBR131W Subunit of a heterodimeric guanine nucleotide exchange factor (GEF) genetic 1 1 1 Synthetic Growth Defect
DPH2 YKL191W Protein required for synthesis of diphthamide genetic 1 1 1 Synthetic Growth Defect
DPH1 YIL103W Protein required for synthesis of diphthamide genetic 1 1 1 Synthetic Growth Defect
PHO2 YDL106C Homeobox transcription factor genetic 1 1 1 Synthetic Growth Defect
GOS1 YHL031C v-SNARE protein involved in Golgi transport genetic 1 1 1 Synthetic Growth Defect
SNX4 YJL036W Sorting nexin genetic 1 1 1 Synthetic Growth Defect
SSA2 YLL024C HSP70 family ATP-binding protein physical 1 1 1 Affinity Capture-MS
OST4 YDL232W Subunit of the oligosaccharyltransferase complex of the ER lumen genetic 1 1 1 Synthetic Growth Defect
MBF1 YOR298C-A Transcriptional coactivator genetic 1 1 1 Synthetic Growth Defect
ERV46 YAL042W Protein localized to COPII-coated vesicles genetic 1 1 1 Synthetic Growth Defect
CSG2 YBR036C Endoplasmic reticulum membrane protein genetic 1 1 1 Synthetic Growth Defect
GYP1 YOR070C Cis-golgi GTPase-activating protein (GAP) for yeast Rabs genetic 1 1 1 Synthetic Growth Defect
PPR1 YLR014C Zinc finger transcription factor genetic 1 1 1 Synthetic Growth Defect
EMC1 YCL045C Member of conserved endoplasmic reticulum membrane complex genetic 1 1 1 Synthetic Growth Defect
SMI1 YGR229C Protein involved in the regulation of cell wall synthesis genetic 1 1 1 Synthetic Growth Defect
INP53 YOR109W Polyphosphatidylinositol phosphatase genetic 1 1 1 Synthetic Growth Defect
HMT1 YBR034C Nuclear SAM-dependent mono- and asymmetric methyltransferase genetic 1 1 1 Synthetic Growth Defect
DPH6 YLR143W Diphthamide synthetase genetic 1 1 1 Synthetic Growth Defect
MAC1 YMR021C Copper-sensing transcription factor genetic 1 1 1 Synthetic Growth Defect
CDC19 YAL038W Pyruvate kinase physical 1 1 1 Affinity Capture-MS
MON1 YGL124C Subunit of a heterodimeric guanine nucleotide exchange factor (GEF) genetic 1 1 1 Synthetic Growth Defect
CLA4 YNL298W Cdc42p-activated signal transducing kinase genetic 1 1 1 Synthetic Growth Defect
CHS5 YLR330W Component of the exomer complex genetic 1 1 1 Synthetic Growth Defect
TCO89 YPL180W Subunit of TORC1 (Tor1p or Tor2p-Kog1p-Lst8p-Tco89p) genetic 1 1 1 Synthetic Growth Defect
VAC8 YEL013W Vacuole-specific Myo2p receptor genetic 1 1 1 Synthetic Growth Defect
CPR7 YJR032W Peptidyl-prolyl cis-trans isomerase (cyclophilin) genetic 1 1 1 Synthetic Growth Defect
KEX2 YNL238W Kexin, a subtilisin-like protease (proprotein convertase) genetic 1 1 1 Synthetic Growth Defect
SWC3 YAL011W Protein of unknown function genetic 1 1 1 Synthetic Growth Defect
SUR1 YPL057C Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit genetic 1 1 1 Synthetic Growth Defect
BSD2 YBR290W Heavy metal ion homeostasis protein genetic 1 1 1 Synthetic Growth Defect
RIM20 YOR275C Protein involved in proteolytic activation of Rim101p genetic 1 1 1 Synthetic Growth Defect
DID2 YKR035W-A Class E protein of the vacuolar protein-sorting (Vps) pathway genetic 1 1 1 Synthetic Growth Defect
ARL3 YPL051W ARF-like small GTPase of the RAS superfamily genetic 1 1 1 Synthetic Growth Defect
DOM34 YNL001W Protein that facilitates ribosomal subunit dissociation genetic 1 1 1 Synthetic Growth Defect
RNR4 YGR180C Ribonucleotide-diphosphate reductase (RNR) small subunit genetic 1 1 1 Synthetic Growth Defect
RPN4 YDL020C Transcription factor that stimulates expression of proteasome genes genetic 1 1 1 Synthetic Growth Defect
SOH1 YGL127C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Synthetic Growth Defect
EAF7 YNL136W Subunit of the NuA4 histone acetyltransferase complex genetic 1 1 1 Synthetic Growth Defect
SYS1 YJL004C Integral membrane protein of the Golgi genetic 1 1 1 Synthetic Growth Defect
MOG1 YJR074W Conserved nuclear protein that interacts with GTP-Gsp1p genetic 1 1 1 Synthetic Growth Defect
PAR32 YDL173W Low complexity protein genetic 1 1 1 Synthetic Growth Defect
RPL13A YDL082W Ribosomal 60S subunit protein L13A genetic 1 1 1 Synthetic Growth Defect
RPL29 YFR032C-A Ribosomal 60S subunit protein L29 genetic 1 1 1 Synthetic Growth Defect
ORM2 YLR350W Protein that mediates sphingolipid homeostasis genetic 1 1 1 Synthetic Growth Defect
MIT1 YEL007W Transcriptional regulator of pseudohyphal growth genetic 1 1 1 Synthetic Growth Defect
ADI1 YMR009W Acireductone dioxygenease involved in methionine salvage pathway genetic 1 1 1 Synthetic Growth Defect
SAC7 YDR389W GTPase activating protein (GAP) for Rho1p genetic 1 1 1 Synthetic Growth Defect
MRC1 YCL061C S-phase checkpoint protein required for DNA replication genetic 1 1 1 Synthetic Growth Defect
COY1 YKL179C Golgi membrane protein with similarity to mammalian CASP genetic 1 1 1 Synthetic Growth Defect
TPM1 YNL079C Major isoform of tropomyosin genetic 1 1 1 Synthetic Growth Defect
GEF1 YJR040W Voltage-gated chloride channel genetic 1 1 1 Synthetic Growth Defect
FRA1 YLL029W Protein involved in negative regulation of iron regulon transcription genetic 1 1 1 Synthetic Growth Defect
CSF1 YLR087C Protein with structural similarity to lipid transport protein Vps13p genetic 1 1 1 Synthetic Growth Defect
MMS1 YPR164W Subunit of E3 ubiquitin ligase complex involved in replication repair genetic 1 1 1 Synthetic Growth Defect
KEX1 YGL203C Cell death protease essential for hypochlorite-induced apoptosis genetic 1 1 1 Synthetic Growth Defect
PAH1 YMR165C Mg2+-dependent phosphatidate (PA) phosphatase genetic 1 1 1 Synthetic Growth Defect
CUE1 YMR264W Ubiquitin-binding protein genetic 1 1 1 Synthetic Growth Defect
FAT1 YBR041W Very long chain fatty acyl-CoA synthetase and fatty acid transporter genetic 1 1 1 Positive Genetic
SAT4 YCR008W Ser/Thr protein kinase involved in salt tolerance, nutrient response genetic 1 1 1 Synthetic Growth Defect
UME6 YDR207C Rpd3L histone deacetylase complex subunit genetic 1 1 1 Synthetic Growth Defect
STP1 YDR463W Transcription factor genetic 1 1 1 Synthetic Growth Defect
UBP3 YER151C Ubiquitin-specific protease that cleaves Ub-protein fusions genetic 1 1 1 Synthetic Growth Defect
RIM8 YGL045W Protein involved in proteolytic activation of Rim101p genetic 1 1 1 Synthetic Growth Defect
PSD2 YGR170W Phosphatidylserine decarboxylase of the Golgi and vacuolar membranes genetic 1 1 1 Synthetic Growth Defect
LYS14 YDR034C Transcriptional activator involved in regulating lysine biosynthesis genetic 1 1 1 Synthetic Growth Defect
SEC28 YIL076W Epsilon-COP subunit of the coatomer genetic 1 1 1 Synthetic Growth Defect
VHS2 YIL135C Regulator of septin dynamics genetic 1 1 1 Synthetic Growth Defect
FTR1 YER145C High affinity iron permease genetic 1 1 1 Synthetic Growth Defect
ELF1 YKL160W Transcription elongation factor with a conserved zinc finger domain genetic 1 1 1 Synthetic Growth Defect
SAC1 YKL212W Phosphatidylinositol phosphate phosphatase genetic 1 1 1 Synthetic Growth Defect
CYK3 YDL117W SH3-domain protein located in the bud neck and cytokinetic actin ring genetic 1 1 1 Synthetic Growth Defect
SIS2 YKR072C Negative regulatory subunit of protein phosphatase 1 (Ppz1p) genetic 1 1 1 Synthetic Growth Defect
RTT109 YLL002W Histone acetyltransferase genetic 1 1 1 Synthetic Growth Defect
VAC14 YLR386W Enzyme regulator genetic 1 1 1 Synthetic Growth Defect
CAJ1 YER048C Nuclear type II J heat shock protein of the E. coli dnaJ family genetic 1 1 1 Synthetic Growth Defect
PSP2 YML017W Asn rich cytoplasmic protein that contains RGG motifs genetic 1 1 1 Synthetic Growth Defect
UBX4 YMR067C UBX domain-containing protein that interacts with Cdc48p genetic 1 1 1 Synthetic Growth Defect
POC4 YPL144W Component of a heterodimeric Poc4p-Irc25p chaperone genetic 1 1 1 Synthetic Growth Defect
UBP14 YBR058C Ubiquitin-specific protease genetic 1 1 1 Synthetic Growth Defect
RIM21 YNL294C pH sensor molecule, component of the RIM101 pathway genetic 1 1 1 Synthetic Growth Defect
NPT1 YOR209C Nicotinate phosphoribosyltransferase genetic 1 1 1 Synthetic Growth Defect
IRC25 YLR021W Component of a heterodimeric Poc4p-Irc25p chaperone genetic 1 1 1 Synthetic Growth Defect
KRE28 YDR532C Subunit of a kinetochore-microtubule binding complex genetic 1 1 1 Synthetic Growth Defect
CWH41 YGL027C Processing alpha glucosidase I genetic 1 1 1 Synthetic Growth Defect
RPL13B YMR142C Ribosomal 60S subunit protein L13B genetic 1 1 1 Synthetic Growth Defect
SPB4 YFL002C Putative ATP-dependent RNA helicase genetic 1 1 1 Negative Genetic
RPL17B YJL177W Ribosomal 60S subunit protein L17B genetic 1 1 1 Synthetic Growth Defect
GSH1 YJL101C Gamma glutamylcysteine synthetase genetic 1 1 1 Synthetic Growth Defect
CHS6 YJL099W Member of the ChAPs (Chs5p-Arf1p-binding proteins) family genetic 1 1 1 Synthetic Growth Defect
DPH5 YLR172C Methyltransferase required for synthesis of diphthamide genetic 1 1 1 Synthetic Growth Defect
OCA5 YHL029C Cytoplasmic protein required for replication of Brome mosaic virus genetic 1 1 1 Synthetic Growth Defect
SQS1 YNL224C Protein that stimulates the ATPase and helicase activities of Prp43p genetic 1 1 1 Synthetic Growth Defect
GVP36 YIL041W BAR domain protein that localizes to early and late Golgi vesicles genetic 1 1 1 Synthetic Growth Defect
GCS1 YDL226C ADP-ribosylation factor GTPase activating protein (ARF GAP) genetic 1 1 1 Synthetic Growth Defect
BST1 YFL025C GPI inositol deacylase of the endoplasmic reticulum (ER) genetic 1 1 1 Synthetic Growth Defect
ARO2 YGL148W Bifunctional chorismate synthase and flavin reductase genetic 1 1 1 Synthetic Growth Defect
RPS29B YDL061C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Synthetic Growth Defect
RPS19A YOL121C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Synthetic Growth Defect
ATG21 YPL100W Phosphoinositide binding protein genetic 1 1 1 Synthetic Growth Defect
FPS1 YLL043W Aquaglyceroporin, plasma membrane channel genetic 1 1 1 Synthetic Growth Defect
AGE2 YIL044C ADP-ribosylation factor (ARF) GTPase activating protein (GAP) effector genetic 1 1 1 Synthetic Growth Defect
PTK2 YJR059W Serine/threonine protein kinase genetic 1 1 1 Synthetic Growth Defect
GUP1 YGL084C Plasma membrane protein involved in remodeling GPI anchors genetic 1 1 1 Synthetic Growth Defect
RUD3 YOR216C Golgi matrix protein genetic 1 1 1 Synthetic Growth Defect
SKG1 YKR100C Transmembrane protein with a role in cell wall polymer composition genetic 1 1 1 Synthetic Growth Defect
SIT1 YEL065W Ferrioxamine B transporter genetic 1 1 1 Synthetic Growth Defect
ALG6 YOR002W ER-luminal alpha 1,3 glucosyltransferase genetic 1 1 1 Synthetic Growth Defect
TRP1 YDR007W Phosphoribosylanthranilate isomerase genetic 1 1 1 Synthetic Growth Defect
SMF1 YOL122C Divalent metal ion transporter genetic 1 1 1 Synthetic Growth Defect
RPS27B YHR021C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Synthetic Growth Defect
MNN2 YBR015C Alpha-1,2-mannosyltransferase genetic 1 1 1 Synthetic Growth Defect
RRT2 YBR246W Methylesterase performing penultimate step of diphthamide biosynthesis genetic 1 1 1 Synthetic Growth Defect
PEX31 YGR004W Peroxisomal integral membrane protein genetic 1 1 1 Synthetic Growth Defect
THR1 YHR025W Homoserine kinase genetic 1 1 1 Synthetic Growth Defect
JJJ3 YJR097W Iron-binding protein genetic 1 1 1 Synthetic Growth Defect
MDM34 YGL219C Mitochondrial component of the ERMES complex genetic 1 1 1 Synthetic Growth Defect
RPL22B YFL034C-A Ribosomal 60S subunit protein L22A genetic 1 1 1 Synthetic Growth Defect
RPS16B YDL083C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Synthetic Growth Defect
SHE4 YOR035C Protein containing a UCS (UNC-45/CRO1/SHE4) domain genetic 1 1 1 Synthetic Growth Defect
DFG16 YOR030W Probable multiple transmembrane protein genetic 1 1 1 Synthetic Growth Defect
COM2 YER130C Transcription factor that binds IME1 Upstream Activation Signal (UAS) genetic 1 1 1 Negative Genetic
SHE1 YBL031W Mitotic spindle protein genetic 1 1 1 Synthetic Growth Defect
PMC1 YGL006W Vacuolar Ca2+ ATPase involved in depleting cytosol of Ca2+ ions genetic 1 1 1 Synthetic Growth Defect
BAP2 YBR068C High-affinity leucine permease genetic 1 1 1 Synthetic Growth Defect
ILM1 YJR118C Protein of unknown function genetic 1 1 1 Synthetic Growth Defect
LGE1 YPL055C Protein involved in histone H2B ubiquitination genetic 1 1 1 Synthetic Growth Defect
VPH1 YOR270C Subunit a of the vacuolar-ATPase V0 domain physical 1 1 1 PCA
VPH1 YOR270C Subunit a of the vacuolar-ATPase V0 domain genetic 1 1 1 Synthetic Growth Defect
YNL190W YNL190W Hydrophilin essential in desiccation-rehydration process physical 1 1 1 PCA
VPS13 YLL040C Lipid transport protein involved in prospore membrane morphogenesis genetic 1 1 1 Synthetic Growth Defect
VPS41 YDR080W Subunit of the HOPS endocytic tethering complex genetic 1 1 1 Synthetic Growth Defect
VPS62 YGR141W Vacuolar protein sorting (VPS) protein genetic 1 1 1 Synthetic Growth Defect
VPS73 YGL104C Mitochondrial protein genetic 1 1 1 Synthetic Growth Defect
VPS9 YML097C Guanine nucleotide exchange factor (GEF) and ubiquitin receptor genetic 1 1 1 Synthetic Growth Defect
XRS2 YDR369C FHA domain-containing component of the Mre11 complex genetic 1 1 1 Synthetic Growth Defect
YAP1801 YHR161C Protein of the AP180 family, involved in clathrin cage assembly genetic 1 1 1 Synthetic Growth Defect
YAR029W YAR029W Member of DUP240 gene family but contains no transmembrane domains genetic 1 1 1 Synthetic Growth Defect
YCR007C YCR007C Putative integral membrane protein genetic 1 1 1 Synthetic Growth Defect
YDJ1 YNL064C Type I HSP40 co-chaperone genetic 1 1 1 Synthetic Growth Defect
YGR122W YGR122W Protein that may be involved in pH regulation genetic 1 1 1 Synthetic Growth Defect
YGR237C YGR237C Putative protein of unknown function genetic 1 1 1 Synthetic Growth Defect
YKL069W YKL069W Methionine-R-sulfoxide reductase genetic 1 1 1 Synthetic Growth Defect
YPR089W YPR089W Protein of unknown function genetic 1 1 1 Synthetic Growth Defect
YUR1 YJL139C Mannosyltransferase involved in protein N-glycosylation genetic 1 1 1 Synthetic Growth Defect
VPS71 YML041C Nucleosome-binding component of the SWR1 complex genetic 1 1 1 Synthetic Growth Defect
VPS72 YDR485C Htz1p-binding component of the SWR1 complex genetic 1 1 1 Synthetic Growth Defect
YAK1 YJL141C Serine-threonine protein kinase genetic 1 1 1 Synthetic Growth Defect
YBR284W YBR284W Putative metallo-dependent hydrolase superfamily protein genetic 1 1 1 Synthetic Growth Defect
YEH1 YLL012W Steryl ester hydrolase genetic 1 1 1 Synthetic Growth Defect
YND1 YER005W Apyrase with wide substrate specificity genetic 1 1 1 Synthetic Growth Defect
ZUO1 YGR285C Ribosome-associated chaperone genetic 1 1 1 Synthetic Growth Defect
VPS21 YOR089C Endosomal Rab family GTPase genetic 1 1 1 Synthetic Growth Defect
VPS55 YJR044C Late endosomal protein involved in late endosome to vacuole transport genetic 1 1 1 Synthetic Growth Defect
VPS60 YDR486C Protein involved in late endosome to vacuole transport genetic 1 1 1 Synthetic Growth Defect
VTA1 YLR181C Multivesicular body (MVB) protein genetic 1 1 1 Synthetic Growth Defect
VTS1 YOR359W Flap-structured DNA-binding and RNA-binding protein genetic 1 1 1 Synthetic Growth Defect
YTA7 YGR270W Chromatin-binding ATPase that regulates histone gene expression genetic 1 1 1 Synthetic Growth Defect
ZRC1 YMR243C Vacuolar membrane zinc transporter genetic 1 1 1 Synthetic Growth Defect
VPS33 YLR396C ATP-binding protein that is a subunit of the HOPS and CORVET complexes genetic 1 1 1 Synthetic Growth Defect
VPS17 YOR132W Subunit of the membrane-associated retromer complex genetic 1 1 1 Synthetic Growth Defect
VPS27 YNR006W Endosomal protein that forms a complex with Hse1p genetic 1 1 1 Synthetic Growth Defect
XRN1 YGL173C Evolutionarily-conserved 5'-3' exonuclease genetic 1 1 1 Synthetic Growth Defect
VPS24 YKL041W One of four subunits of the ESCRT-III complex genetic 1 1 1 Synthetic Growth Defect
VPS29 YHR012W Subunit of the membrane-associated retromer complex genetic 1 1 1 Synthetic Growth Defect
VPS35 YJL154C Endosomal subunit of membrane-associated retromer complex genetic 1 1 1 Synthetic Growth Defect
VPS4 YPR173C AAA-ATPase involved in multivesicular body (MVB) protein sorting genetic 1 1 1 Synthetic Growth Defect
VPS5 YOR069W Nexin-1 homolog genetic 1 1 1 Synthetic Growth Defect
VTC1 YER072W Regulatory subunit of the vacuolar transporter chaperone (VTC) complex genetic 1 1 1 Synthetic Growth Defect
VTC4 YJL012C Vacuolar membrane polyphosphate polymerase genetic 1 1 1 Synthetic Growth Defect
YCK3 YER123W Palmitoylated vacuolar membrane-localized casein kinase I isoform genetic 1 1 1 Synthetic Growth Defect
YPT7 YML001W Rab family GTPase genetic 1 1 1 Synthetic Growth Defect
YAR066W YAR066W Putative GPI protein genetic 1 1 1 Negative Genetic
YLR031W YLR031W Putative protein of unknown function genetic 1 1 1 Negative Genetic
ERG3 YLR056W C-5 sterol desaturase genetic 1 1 1 Synthetic Growth Defect
CCW12 YLR110C Cell wall mannoprotein genetic 1 1 1 Synthetic Growth Defect
KRE1 YNL322C Cell wall glycoprotein involved in beta-glucan assembly genetic 1 1 1 Synthetic Growth Defect
ARO7 YPR060C Chorismate mutase genetic 1 1 1 Synthetic Growth Defect
TAE1 YBR261C AdoMet-dependent proline methyltransferase genetic 1 1 1 Synthetic Growth Defect
ATG15 YCR068W Phospholipase genetic 1 1 1 Synthetic Growth Defect
MTC2 YKL098W Protein of unknown function genetic 1 1 1 Synthetic Growth Defect
AIM14 YGL160W NADPH oxidase localized to the perinuclear ER genetic 1 1 1 Synthetic Growth Defect
RMD8 YFR048W Cytosolic protein required for sporulation genetic 1 1 1 Synthetic Growth Defect
SMF3 YLR034C Putative divalent metal ion transporter involved in iron homeostasis genetic 1 1 1 Synthetic Growth Defect
TVS1 YCR061W Protein of unknown function genetic 1 1 1 Synthetic Growth Defect
TMA17 YDL110C Regulatory gamma subunit of fatty acid synthase (FAS) genetic 1 1 1 Synthetic Growth Defect
SCW10 YMR305C Cell wall protein with similarity to glucanases genetic 1 1 1 Synthetic Growth Defect
RPO41 YFL036W Mitochondrial RNA polymerase genetic 1 1 1 Synthetic Growth Defect
NCS2 YNL119W Protein required for uridine thiolation of Lys(UUU) and Glu(UUC) tRNAs genetic 1 1 1 Synthetic Growth Defect
NCS6 YGL211W Protein required for uridine thiolation of Gln, Lys, and Glu tRNAs genetic 1 1 1 Synthetic Growth Defect
RPS6B YBR181C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Synthetic Growth Defect
TDH3 YGR192C Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 3 physical 1 1 1 Affinity Capture-MS
ERD1 YDR414C Predicted membrane protein required for lumenal ER protein retention genetic 1 1 1 Synthetic Growth Defect
CCC2 YDR270W Cu(+2)-transporting P-type ATPase genetic 1 1 1 Synthetic Growth Defect
FMC1 YIL098C Mitochondrial matrix protein genetic 1 1 1 Synthetic Growth Defect
MSC1 YML128C Protein of unknown function genetic 1 1 1 Synthetic Growth Defect
APS3 YJL024C Small subunit of the clathrin-associated adaptor complex AP-3 genetic 1 1 1 Synthetic Growth Defect
GSH2 YOL049W Glutathione synthetase genetic 1 1 1 Synthetic Growth Defect
LIP2 YLR239C Lipoyl ligase genetic 1 1 1 Synthetic Growth Defect
DLT1 YMR126C Protein of unknown function genetic 1 1 1 Synthetic Growth Defect
AVT7 YIL088C Vacuolar amino acid transporter genetic 1 1 1 Synthetic Growth Defect
DFR1 YOR236W Dihydrofolate reductase involved in tetrahydrofolate biosynthesis genetic 1 1 1 Negative Genetic
PMP3 YDR276C Small plasma membrane protein genetic 1 1 1 Synthetic Growth Defect
ROT2 YBR229C Glucosidase II catalytic subunit genetic 1 1 1 Synthetic Growth Defect
SWF1 YDR126W Palmitoyltransferase that acts on transmembrane proteins genetic 1 1 1 Synthetic Growth Defect
PER1 YCR044C Protein of the endoplasmic reticulum genetic 1 1 1 Synthetic Growth Defect
CNE1 YAL058W Calnexin genetic 1 1 1 Synthetic Growth Defect
ALG8 YOR067C Glucosyl transferase genetic 1 1 1 Synthetic Growth Defect
SPE1 YKL184W Ornithine decarboxylase genetic 1 1 1 Synthetic Growth Defect
SDH8 YBR269C Protein required for assembly of succinate dehydrogenase genetic 1 1 1 Synthetic Growth Defect
RPL41B YDL133C-A Ribosomal 60S subunit protein L41B genetic 1 1 1 Synthetic Growth Defect
RPS21B YJL136C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Synthetic Growth Defect
RPS28B YLR264W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Synthetic Growth Defect
SER2 YGR208W Phosphoserine phosphatase of the phosphoglycerate pathway genetic 1 1 1 Synthetic Growth Defect
MET22 YOL064C Bisphosphate-3'-nucleotidase genetic 1 1 1 Synthetic Growth Defect
SNA2 YDR525W-A Protein of unknown function genetic 1 1 1 Synthetic Growth Defect
OCT1 YKL134C Mitochondrial intermediate peptidase genetic 1 1 1 Synthetic Growth Defect
VID22 YLR373C G-quadruplex (G4) DNA binding protein genetic 1 1 1 Synthetic Growth Defect
RKR1 YMR247C RING domain E3 ubiquitin ligase genetic 1 1 1 Synthetic Growth Defect
RSM28 YDR494W Mitochondrial ribosomal protein of the small subunit genetic 1 1 1 Synthetic Growth Defect
LST4 YKL176C Subunit of the Lst4p-Lst7p GTPase activating protein complex for Gtr2p genetic 1 1 1 Synthetic Growth Defect
ECM38 YLR299W Gamma-glutamyltranspeptidase genetic 1 1 1 Synthetic Growth Defect
URM1 YIL008W Ubiquitin-like protein involved in thiolation of cytoplasmic tRNAs genetic 1 1 1 Synthetic Growth Defect
ICE2 YIL090W Integral ER membrane protein with type-III transmembrane domains genetic 1 1 1 Synthetic Growth Defect
ARG2 YJL071W Acetylglutamate synthase (glutamate N-acetyltransferase) genetic 1 1 1 Synthetic Growth Defect
IRC21 YMR073C Protein of unknown function genetic 1 1 1 Synthetic Growth Defect
SIM1 YIL123W Protein of the SUN family (Sim1p, Uth1p, Nca3p, Sun4p) genetic 1 1 1 Synthetic Growth Defect
SWP82 YFL049W Member of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Synthetic Growth Defect
UBP13 YBL067C Ubiquitin-specific protease that cleaves Ub-protein fusions genetic 1 1 1 Synthetic Growth Defect
PPM1 YDR435C Carboxyl methyltransferase genetic 1 1 1 Synthetic Growth Defect
RRF1 YHR038W Mitochondrial ribosome recycling factor genetic 1 1 1 Synthetic Growth Defect
VMS1 YDR049W Peptidyl-tRNA hydrolase that releases stalled peptides from ribosomes, genetic 1 1 1 Synthetic Growth Defect
MRX4 YPL168W Protein that associates with mitochondrial ribosome genetic 1 1 1 Synthetic Growth Defect
UPF3 YGR072W Component of the nonsense-mediated mRNA decay (NMD) pathway genetic 1 1 1 Synthetic Growth Defect
MTC4 YBR255W Protein of unknown function genetic 1 1 1 Synthetic Growth Defect
THR4 YCR053W Threonine synthase genetic 1 1 1 Synthetic Growth Defect
SPF1 YEL031W P-type ATPase, ion transporter of the ER membrane genetic 1 1 1 Synthetic Growth Defect
TDA4 YJR116W Protein distantly similar to ceramide synthases, Lag1p and Lac1p genetic 1 1 1 Synthetic Growth Defect
ARG7 YMR062C Mitochondrial ornithine acetyltransferase genetic 1 1 1 Synthetic Growth Defect
TRK1 YJL129C Component of the Trk1p-Trk2p potassium transport system genetic 1 1 1 Synthetic Growth Defect
MAY24 YPR153W Peripheral ER membrane protein genetic 1 1 1 Synthetic Growth Defect
VAM10 YOR068C Protein involved in vacuole morphogenesis genetic 1 1 1 Synthetic Growth Defect
RIM9 YMR063W Plasma membrane protein of unknown function genetic 1 1 1 Synthetic Growth Defect
MTC6 YHR151C Protein of unknown function genetic 1 1 1 Synthetic Growth Defect
TMA23 YMR269W Nucleolar protein implicated in ribosome biogenesis genetic 1 1 1 Synthetic Growth Defect
TOS2 YGR221C Protein involved in localization of Cdc24p to the site of bud growth genetic 1 1 1 Synthetic Growth Defect
TRP4 YDR354W Anthranilate phosphoribosyl transferase genetic 1 1 1 Synthetic Growth Defect
URA4 YLR420W Dihydroorotase genetic 1 1 1 Synthetic Growth Defect