Standard name Systematic name Name description Description
ELO3 YLR372W Elongase Elongase; involved in fatty acid and sphingolipid biosynthesis; synthesizes very long chain 20-26-carbon fatty acids from C18-CoA primers; involved in regulation of sphingolipid biosynthesis; lethality of the elo2 elo3 double null mutation is functionally complemented by human ELOVL1 and weakly complemented by human ELOVL3 or ELOV7
Visualize the interactome of ELO3
Links to external databases:
SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)
G1(P) 18

CYCLoPs localization & abundance

WT1 WT2 WT3
ER 0.909 0.941 0.949
Golgi NaN NaN 0.055
Nuc Periphery NaN NaN 0.082

GFP localization & abundance

GFP localization GFP abundance
no data no data

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
ELO3 4 0 0 0 0

Enzyme information

Catalyzed reactions in Yeast8
r_2160 (elongase III (3-oxohexacosanoyl-CoA)), r_2158 (elongase II or III (3-oxodocosanoyl-CoA)), r_2157 (elongase II or III (3-oxoicosanoyl-CoA)), r_2159 (elongase II or III (3-oxotetracosanoyl-CoA))

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
ELO2 YCR034W Fatty acid elongase, involved in sphingolipid biosynthesis genetic 9 5 7 Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Positive Genetic, Negative Genetic, Synthetic Lethality, Phenotypic Enhancement, Synthetic Growth Defect, Synthetic Lethality
RVS161 YCR009C Amphiphysin-like lipid raft protein genetic 8 4 5 Synthetic Rescue, Phenotypic Suppression, Synthetic Rescue, Phenotypic Suppression, Phenotypic Suppression, Phenotypic Enhancement, Synthetic Rescue, Positive Genetic
LCB3 YJL134W Long-chain base-1-phosphate phosphatase genetic 7 2 6 Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
FAT1 YBR041W Very long chain fatty acyl-CoA synthetase and fatty acid transporter genetic 7 2 6 Phenotypic Enhancement, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
GUP1 YGL084C Plasma membrane protein involved in remodeling GPI anchors genetic 7 1 5 Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic
ERG2 YMR202W C-8 sterol isomerase genetic 6 3 5 Phenotypic Suppression, Synthetic Rescue, Synthetic Rescue, Phenotypic Suppression, Phenotypic Suppression, Positive Genetic
ERD1 YDR414C Predicted membrane protein required for lumenal ER protein retention genetic 6 2 5 Negative Genetic, Phenotypic Suppression, Phenotypic Suppression, Negative Genetic, Negative Genetic, Negative Genetic
DPL1 YDR294C Dihydrosphingosine phosphate lyase genetic 6 1 5 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
RIC1 YLR039C Protein involved in retrograde transport to the cis-Golgi network genetic 6 1 4 Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic
LAG1 YHL003C Ceramide synthase component genetic 5 1 5 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
RVS167 YDR388W Calmodulin-binding actin-associated protein genetic 4 3 4 Phenotypic Suppression, Positive Genetic, Positive Genetic, Synthetic Rescue
TSC13 YDL015C Enoyl reductase genetic 4 2 4 Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic
LIP1 YMR298W Ceramide synthase subunit genetic 4 2 4 Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
SPF1 YEL031W P-type ATPase, ion transporter of the ER membrane genetic 4 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
HOC1 YJR075W Alpha-1,6-mannosyltransferase genetic 4 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
VPS9 YML097C Guanine nucleotide exchange factor (GEF) and ubiquitin receptor genetic 4 2 3 Negative Genetic, Phenotypic Suppression, Phenotypic Suppression, Negative Genetic
LAC1 YKL008C Ceramide synthase component genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
TRS20 YBR254C Core component of transport protein particle (TRAPP) complexes I-III genetic 4 1 3 Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic
SUR1 YPL057C Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
STE24 YJR117W Highly conserved zinc metalloprotease genetic 4 2 2 Phenotypic Suppression, Phenotypic Suppression, Negative Genetic, Negative Genetic
ILM1 YJR118C Protein of unknown function genetic 4 1 2 Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic
UBX2 YML013W Bridging factor involved in ER-associated protein degradation (ERAD) genetic 4 1 2 Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic
FKH1 YIL131C Forkhead family transcription factor regulation 3 3 3 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation- exonuclease evidence, ChEC-Seq experiments
ETR1 YBR026C 2-enoyl thioester reductase genetic 3 2 3 Positive Genetic, Positive Genetic, Synthetic Rescue
ERG3 YLR056W C-5 sterol desaturase genetic 3 2 3 Positive Genetic, Negative Genetic, Negative Genetic
IPT1 YDR072C Inositolphosphotransferase genetic 3 2 3 Positive Genetic, Negative Genetic, Negative Genetic
VPS74 YDR372C Golgi PI4K effector, PtdIns4P sensor, and retention receptor genetic 3 2 3 Negative Genetic, Synthetic Growth Defect, Negative Genetic
PMA1 YGL008C Plasma membrane P2-type H+-ATPase genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
MNN11 YJL183W Subunit of a Golgi mannosyltransferase complex genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
SNF4 YGL115W Activating gamma subunit of the AMP-activated Snf1p kinase complex genetic 3 1 3 Positive Genetic, Positive Genetic, Positive Genetic
TPM1 YNL079C Major isoform of tropomyosin genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
CSG2 YBR036C Endoplasmic reticulum membrane protein genetic 3 1 3 Positive Genetic, Positive Genetic, Positive Genetic
LCB4 YOR171C Sphingoid long-chain base kinase genetic 3 3 2 Negative Genetic, Synthetic Rescue, Phenotypic Suppression
ARF1 YDL192W ADP-ribosylation factor genetic 3 2 2 Phenotypic Suppression, Phenotypic Suppression, Negative Genetic
ERV14 YGL054C COPII-coated vesicle protein genetic 3 2 2 Phenotypic Suppression, Phenotypic Suppression, Negative Genetic
MMM1 YLL006W ER integral membrane protein, ERMES complex subunit genetic 3 2 2 Positive Genetic, Positive Genetic, Synthetic Rescue
KEX2 YNL238W Kexin, a subtilisin-like protease (proprotein convertase) genetic 3 2 2 Phenotypic Suppression, Phenotypic Suppression, Negative Genetic
VPS29 YHR012W Subunit of the membrane-associated retromer complex genetic 3 2 2 Negative Genetic, Phenotypic Suppression, Phenotypic Suppression
IRA2 YOL081W GTPase-activating protein genetic 3 2 2 Positive Genetic, Negative Genetic, Negative Genetic
ERP1 YAR002C-A Member of the p24 family involved in ER to Golgi transport genetic 3 2 2 Phenotypic Suppression, Phenotypic Suppression, Negative Genetic
ERV25 YML012W Member of the p24 family involved in ER to Golgi transport genetic 3 2 2 Phenotypic Suppression, Phenotypic Suppression, Negative Genetic
GCR2 YNL199C Transcriptional activator of genes involved in glycolysis genetic 3 2 2 Phenotypic Suppression, Phenotypic Suppression, Synthetic Rescue
MGA2 YIR033W ER membrane protein involved in regulation of OLE1 transcription genetic 3 2 2 Phenotypic Suppression, Phenotypic Suppression, Positive Genetic
VPS52 YDR484W Component of the GARP (Golgi-associated retrograde protein) complex genetic 3 2 2 Phenotypic Suppression, Phenotypic Suppression, Positive Genetic
MDM32 YOR147W Mitochondrial inner membrane protein with similarity to Mdm31p genetic 3 2 2 Positive Genetic, Positive Genetic, Negative Genetic
GEP3 YOR205C Protein required for mitochondrial ribosome small subunit biogenesis genetic 3 2 2 Positive Genetic, Positive Genetic, Negative Genetic
BST1 YFL025C GPI inositol deacylase of the endoplasmic reticulum (ER) genetic 3 2 2 Phenotypic Suppression, Phenotypic Suppression, Synthetic Growth Defect
CCW12 YLR110C Cell wall mannoprotein genetic 3 2 2 Phenotypic Suppression, Phenotypic Suppression, Negative Genetic
RGP1 YDR137W Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) genetic 3 1 2 Positive Genetic, Positive Genetic, Positive Genetic
GET2 YER083C Subunit of the GET complex genetic 3 1 2 Positive Genetic, Positive Genetic, Positive Genetic
MTC4 YBR255W Protein of unknown function genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
ERV41 YML067C Protein localized to COPII-coated vesicles genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
PKR1 YMR123W V-ATPase assembly factor genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
GYP1 YOR070C Cis-golgi GTPase-activating protein (GAP) for yeast Rabs genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
VPS30 YPL120W Subunit of phosphatidylinositol (PtdIns) 3-kinase complexes I and II genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SRO7 YPR032W Effector of Rab GTPase Sec4p genetic 3 1 2 Positive Genetic, Positive Genetic, Positive Genetic
PAM16 YJL104W Subunit of the import motor (PAM complex) genetic 3 2 1 Synthetic Rescue, Synthetic Rescue, Phenotypic Suppression
CDC13 YDL220C Single stranded DNA-binding protein found at TG1-3 telomere G-tails genetic 2 2 2 Synthetic Rescue, Positive Genetic
TSC13 YDL015C Enoyl reductase physical 2 2 2 Affinity Capture-Western, PCA
ERG24 YNL280C C-14 sterol reductase genetic 2 2 2 Phenotypic Suppression, Positive Genetic
SHP1 YBL058W UBX domain-containing substrate adaptor for Cdc48p genetic 2 2 2 Phenotypic Enhancement, Negative Genetic
KCS1 YDR017C Inositol hexakisphosphate and inositol heptakisphosphate kinase genetic 2 2 2 Synthetic Rescue, Positive Genetic
LCB1 YMR296C Component of serine palmitoyltransferase genetic 2 2 2 Synthetic Growth Defect, Phenotypic Suppression
VMA2 YBR127C Subunit B of V1 peripheral membrane domain of vacuolar H+-ATPase genetic 2 2 2 Negative Genetic, Positive Genetic
PEP7 YDR323C Adaptor protein involved in vesicle-mediated vacuolar protein sorting genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
LPD1 YFL018C Dihydrolipoamide dehydrogenase genetic 2 2 2 Positive Genetic, Synthetic Rescue
MCK1 YNL307C Dual-specificity ser/thr and tyrosine protein kinase genetic 2 2 2 Synthetic Rescue, Synthetic Growth Defect
SEC26 YDR238C Essential beta-coat protein of the COPI coatomer genetic 2 2 2 Negative Genetic, Positive Genetic
ORM2 YLR350W Protein that mediates sphingolipid homeostasis genetic 2 2 2 Synthetic Lethality, Dosage Rescue
PHS1 YJL097W Essential 3-hydroxyacyl-CoA dehydratase of the ER membrane genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 2 1 2 DNA to cDNA expression microarray evidence, DNA to cDNA expression microarray evidence
BEM1 YBR200W Protein containing SH3-domains genetic 2 1 2 Negative Genetic, Negative Genetic
EDE1 YBL047C Scaffold protein involved in the formation of early endocytic sites genetic 2 1 2 Negative Genetic, Negative Genetic
DEP1 YAL013W Component of the Rpd3L histone deacetylase complex genetic 2 1 2 Negative Genetic, Negative Genetic
ECM33 YBR078W GPI-anchored protein involved in efficient glucose uptake genetic 2 1 2 Negative Genetic, Negative Genetic
APL4 YPR029C Gamma-adaptin genetic 2 1 2 Negative Genetic, Negative Genetic
BIT61 YJL058C Subunit of TORC2 membrane-associated complex genetic 2 1 2 Negative Genetic, Negative Genetic
RPN11 YFR004W Metalloprotease subunit of 19S regulatory particle physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
NHX1 YDR456W Na+/H+ and K+/H+ exchanger genetic 2 1 2 Negative Genetic, Negative Genetic
WBP1 YEL002C Beta subunit of the oligosaccharyl transferase glycoprotein complex genetic 2 1 2 Negative Genetic, Negative Genetic
GSF2 YML048W Endoplasmic reticulum (ER) localized integral membrane protein genetic 2 1 2 Negative Genetic, Negative Genetic
SWP1 YMR149W Delta subunit of the oligosaccharyl transferase glycoprotein complex genetic 2 1 2 Negative Genetic, Negative Genetic
SSA1 YAL005C ATPase involved in protein folding and NLS-directed nuclear transport physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
PHO85 YPL031C Cyclin-dependent kinase genetic 2 1 2 Synthetic Lethality, Synthetic Lethality
SNC1 YAL030W Vesicle membrane receptor protein (v-SNARE) genetic 2 1 2 Synthetic Rescue, Synthetic Rescue
SFA1 YDL168W Bifunctional alcohol dehydrogenase and formaldehyde dehydrogenase genetic 2 1 2 Negative Genetic, Negative Genetic
UBP1 YDL122W Ubiquitin-specific protease genetic 2 1 2 Negative Genetic, Negative Genetic
SSF2 YDR312W Protein required for ribosomal large subunit maturation genetic 2 1 2 Negative Genetic, Negative Genetic
VMA3 YEL027W Proteolipid subunit c of the V0 domain of vacuolar H(+)-ATPase genetic 2 1 2 Negative Genetic, Negative Genetic
HAP2 YGL237C Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex genetic 2 1 2 Negative Genetic, Negative Genetic
PRP21 YJL203W Subunit of the SF3a splicing factor complex genetic 2 1 2 Negative Genetic, Negative Genetic
TOR2 YKL203C PIK-related protein kinase and rapamycin target genetic 2 1 2 Negative Genetic, Negative Genetic
GPT2 YKR067W Glycerol-3-phosphate/dihydroxyacetone phosphate sn-1 acyltransferase genetic 2 1 2 Negative Genetic, Negative Genetic
FET4 YMR319C Low-affinity Fe(II) transporter of the plasma membrane genetic 2 1 2 Negative Genetic, Negative Genetic
SGF11 YPL047W Integral subunit of SAGA histone acetyltransferase complex genetic 2 1 2 Negative Genetic, Negative Genetic
VPS4 YPR173C AAA-ATPase involved in multivesicular body (MVB) protein sorting genetic 2 1 2 Negative Genetic, Negative Genetic
SEC66 YBR171W Non-essential subunit of Sec63 complex genetic 2 1 2 Negative Genetic, Negative Genetic
SAC7 YDR389W GTPase activating protein (GAP) for Rho1p genetic 2 1 2 Negative Genetic, Negative Genetic
PMR1 YGL167C High affinity Ca2+/Mn2+ P-type ATPase genetic 2 1 2 Negative Genetic, Negative Genetic
MDM34 YGL219C Mitochondrial component of the ERMES complex genetic 2 1 2 Negative Genetic, Negative Genetic
ICE2 YIL090W Integral ER membrane protein with type-III transmembrane domains genetic 2 1 2 Positive Genetic, Positive Genetic
VPS27 YNR006W Endosomal protein that forms a complex with Hse1p genetic 2 1 2 Negative Genetic, Negative Genetic
SPO7 YAL009W Putative regulatory subunit of Nem1p-Spo7p phosphatase holoenzyme genetic 2 1 2 Negative Genetic, Negative Genetic
GDA1 YEL042W Guanosine diphosphatase located in the Golgi genetic 2 1 2 Negative Genetic, Negative Genetic
MON2 YNL297C Protein with a role in endocytosis and vacuole integrity genetic 2 1 2 Negative Genetic, Negative Genetic
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 2 1 2 Positive Genetic, Positive Genetic
CLA4 YNL298W Cdc42p-activated signal transducing kinase genetic 2 1 2 Negative Genetic, Negative Genetic
CST26 YBR042C Acyltransferase genetic 2 1 2 Negative Genetic, Negative Genetic
DAL5 YJR152W Allantoate permease genetic 2 1 2 Negative Genetic, Negative Genetic
ALG3 YBL082C Dolichol-P-Man dependent alpha(1-3) mannosyltransferase genetic 2 1 2 Negative Genetic, Negative Genetic
DSF1 YEL070W Mannitol dehydrogenase genetic 2 1 2 Negative Genetic, Negative Genetic
CNE1 YAL058W Calnexin genetic 2 1 2 Negative Genetic, Negative Genetic
ARG7 YMR062C Mitochondrial ornithine acetyltransferase genetic 2 1 2 Positive Genetic, Positive Genetic
IAH1 YOR126C Isoamyl acetate-hydrolyzing esterase genetic 2 2 1 Positive Genetic, Negative Genetic
EXO70 YJL085W Subunit of the exocyst complex genetic 2 2 1 Positive Genetic, Negative Genetic
VPS21 YOR089C Endosomal Rab family GTPase genetic 2 2 1 Dosage Rescue, Synthetic Growth Defect
EAF1 YDR359C Component of the NuA4 histone acetyltransferase complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
EAF5 YEL018W Non-essential subunit of the NuA4 acetyltransferase complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
DRS2 YAL026C Trans-golgi network aminophospholipid translocase (flippase) genetic 2 1 1 Phenotypic Suppression, Phenotypic Suppression
ACO1 YLR304C Aconitase genetic 2 1 1 Positive Genetic, Positive Genetic
PAN1 YIR006C Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p genetic 2 1 1 Negative Genetic, Negative Genetic
PGA3 YML125C Putative cytochrome b5 reductase, localized to the plasma membrane genetic 2 1 1 Negative Genetic, Negative Genetic
ESA1 YOR244W Catalytic subunit of the histone acetyltransferase complex (NuA4) genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
GCS1 YDL226C ADP-ribosylation factor GTPase activating protein (ARF GAP) genetic 2 1 1 Phenotypic Suppression, Phenotypic Suppression
GLO3 YER122C ADP-ribosylation factor GTPase activating protein (ARF GAP) genetic 2 1 1 Phenotypic Suppression, Phenotypic Suppression
GTR1 YML121W Subunit of a TORC1-stimulating GTPase and the EGO/GSE complex genetic 2 1 1 Phenotypic Suppression, Phenotypic Suppression
LAS21 YJL062W Mannose-ethanolamine phosphotransferase genetic 2 1 1 Phenotypic Suppression, Phenotypic Suppression
LHS1 YKL073W Molecular chaperone of the endoplasmic reticulum lumen genetic 2 1 1 Phenotypic Suppression, Phenotypic Suppression
MTC5 YDR128W Subunit of SEACAT, a subcomplex of the SEA complex genetic 2 1 1 Phenotypic Suppression, Phenotypic Suppression
OST3 YOR085W Gamma subunit of the oligosaccharyltransferase complex of the ER lumen genetic 2 1 1 Phenotypic Suppression, Phenotypic Suppression
PER1 YCR044C Protein of the endoplasmic reticulum genetic 2 1 1 Phenotypic Suppression, Phenotypic Suppression
PMT2 YAL023C Protein O-mannosyltransferase of the ER membrane genetic 2 1 1 Phenotypic Suppression, Phenotypic Suppression
RPN4 YDL020C Transcription factor that stimulates expression of proteasome genes genetic 2 1 1 Phenotypic Suppression, Phenotypic Suppression
SET3 YKR029C Defining member of the SET3 histone deacetylase complex genetic 2 1 1 Phenotypic Suppression, Phenotypic Suppression
SIF2 YBR103W WD40 repeat-containing subunit of Set3C histone deacetylase complex genetic 2 1 1 Phenotypic Suppression, Phenotypic Suppression
SKY1 YMR216C SR protein kinase (SRPK) genetic 2 1 1 Phenotypic Suppression, Phenotypic Suppression
SPT4 YGR063C Spt4p/5p (DSIF) transcription elongation factor complex subunit genetic 2 1 1 Phenotypic Suppression, Phenotypic Suppression
VPS53 YJL029C Component of the GARP (Golgi-associated retrograde protein) complex genetic 2 1 1 Phenotypic Suppression, Phenotypic Suppression
VTC4 YJL012C Vacuolar membrane polyphosphate polymerase genetic 2 1 1 Phenotypic Suppression, Phenotypic Suppression
VPS51 YKR020W Component of the GARP (Golgi-associated retrograde protein) complex genetic 2 1 1 Phenotypic Suppression, Phenotypic Suppression
TED1 YIL039W GPI-glycan remodelase genetic 2 1 1 Phenotypic Suppression, Phenotypic Suppression
VPS54 YDR027C Component of the GARP (Golgi-associated retrograde protein) complex genetic 2 1 1 Phenotypic Suppression, Phenotypic Suppression
THR4 YCR053W Threonine synthase genetic 2 1 1 Positive Genetic, Positive Genetic
MGM101 YJR144W Protein with a role in mitochondrial DNA recombinational repair genetic 2 1 1 Positive Genetic, Positive Genetic
VPH2 YKL119C Integral membrane protein required for V-ATPase function genetic 2 1 1 Positive Genetic, Positive Genetic
GEP5 YLR091W Protein of unknown function genetic 2 1 1 Positive Genetic, Positive Genetic
UPS1 YLR193C Phosphatidic acid transfer protein genetic 2 1 1 Positive Genetic, Positive Genetic
YPT6 YLR262C Rab family GTPase genetic 2 1 1 Positive Genetic, Positive Genetic
VPS71 YML041C Nucleosome-binding component of the SWR1 complex genetic 2 1 1 Positive Genetic, Positive Genetic
PPA2 YMR267W Mitochondrial inorganic pyrophosphatase genetic 2 1 1 Positive Genetic, Positive Genetic
SCS7 YMR272C Sphingolipid alpha-hydroxylase genetic 2 1 1 Positive Genetic, Positive Genetic
HER2 YMR293C Subunit of the trimeric GatFAB AmidoTransferase(AdT) complex genetic 2 1 1 Positive Genetic, Positive Genetic
POR1 YNL055C Mitochondrial porin (voltage-dependent anion channel) genetic 2 1 1 Positive Genetic, Positive Genetic
JJJ1 YNL227C Co-chaperone that stimulates the ATPase activity of Ssa1p genetic 2 1 1 Positive Genetic, Positive Genetic
HTZ1 YOL012C Histone variant H2AZ genetic 2 1 1 Positive Genetic, Positive Genetic
RTG1 YOL067C Transcription factor (bHLH) involved in interorganelle communication genetic 2 1 1 Positive Genetic, Positive Genetic
INO4 YOL108C Transcription factor involved in phospholipid synthesis genetic 2 1 1 Positive Genetic, Positive Genetic
VPH1 YOR270C Subunit a of the vacuolar-ATPase V0 domain genetic 2 1 1 Positive Genetic, Positive Genetic
MIP1 YOR330C Mitochondrial DNA polymerase gamma genetic 2 1 1 Positive Genetic, Positive Genetic
VMA11 YPL234C Vacuolar ATPase V0 domain subunit c' genetic 2 1 1 Positive Genetic, Positive Genetic
YME1 YPR024W Catalytic subunit of i-AAA protease complex genetic 2 1 1 Positive Genetic, Positive Genetic
AIM44 YPL158C Regulator of Cdc42p and Rho1p genetic 2 1 1 Positive Genetic, Positive Genetic
CUE1 YMR264W Ubiquitin-binding protein genetic 2 1 1 Negative Genetic, Negative Genetic
ALG8 YOR067C Glucosyl transferase genetic 2 1 1 Phenotypic Suppression, Phenotypic Suppression
FKH2 YNL068C Forkhead family transcription factor regulation 1 1 1 ChEC-Seq experiments
GCR1 YPL075W Transcriptional activator of genes involved in glycolysis regulation 1 1 1 DNA to cDNA expression microarray evidence
SPT20 YOL148C Subunit of the SAGA transcriptional regulatory complex regulation 1 1 1 DNA to cDNA expression microarray evidence
RAP1 YNL216W Essential DNA-binding transcription regulator that binds many loci regulation 1 1 1 DNA to cDNA expression microarray evidence
YAP6 YDR259C Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
HSF1 YGL073W Trimeric heat shock transcription factor regulation 1 1 1 DNA to cDNA expression microarray evidence
CST6 YIL036W Basic leucine zipper (bZIP) transcription factor from ATF/CREB family regulation 1 1 1 DNA to cDNA expression microarray evidence
UGA3 YDL170W Transcriptional activator for GABA-dependent induction of GABA genes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
INO4 YOL108C Transcription factor involved in phospholipid synthesis regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CDC73 YLR418C Component of the Paf1p complex genetic 1 1 1 Synthetic Rescue
BRE1 YDL074C E3 ubiquitin ligase genetic 1 1 1 Negative Genetic
ARL1 YBR164C Soluble GTPase with a role in regulation of membrane traffic genetic 1 1 1 Negative Genetic
ARP9 YMR033W Component of both the SWI/SNF and RSC chromatin remodeling complexes genetic 1 1 1 Negative Genetic
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 1 1 1 Synthetic Rescue
ECM16 YMR128W Essential DEAH-box ATP-dependent RNA helicase specific to U3 snoRNP physical 1 1 1 Affinity Capture-MS
AOS1 YPR180W Subunit of heterodimeric nuclear SUMO activating enzyme E1 with Uba2p genetic 1 1 1 Negative Genetic
APL2 YKL135C Beta-adaptin subunit of the clathrin-associated protein (AP-1) complex genetic 1 1 1 Positive Genetic
APL6 YGR261C Beta3-like subunit of the yeast AP-3 complex genetic 1 1 1 Positive Genetic
BEM2 YER155C Rho GTPase activating protein (RhoGAP) genetic 1 1 1 Negative Genetic
CCA1 YER168C ATP (CTP):tRNA-specific tRNA nucleotidyltransferase genetic 1 1 1 Negative Genetic
CCL1 YPR025C Cyclin partner of the cyclin-dependent kinase (CDK) Kin28p genetic 1 1 1 Negative Genetic
CAF40 YNL288W Component of the CCR4-NOT transcriptional complex genetic 1 1 1 Synthetic Rescue
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit genetic 1 1 1 Dosage Lethality
ATP11 YNL315C Molecular chaperone genetic 1 1 1 Synthetic Rescue
AVO1 YOL078W Component of the membrane-bound TORC2 complex genetic 1 1 1 Negative Genetic
COX6 YHR051W Subunit VI of cytochrome c oxidase (Complex IV) genetic 1 1 1 Positive Genetic
CTK1 YKL139W Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) genetic 1 1 1 Synthetic Rescue
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
ATG26 YLR189C UDP-glucose:sterol glucosyltransferase genetic 1 1 1 Positive Genetic
DUG1 YFR044C Cys-Gly metallo-di-peptidase genetic 1 1 1 Negative Genetic
AVT4 YNL101W Vacuolar transporter physical 1 1 1 PCA
ACE2 YLR131C Transcription factor required for septum destruction after cytokinesis genetic 1 1 1 Negative Genetic
ALT2 YDR111C Catalytically inactive alanine transaminase genetic 1 1 1 Negative Genetic
BRO1 YPL084W Cytoplasmic class E vacuolar protein sorting (VPS) factor genetic 1 1 1 Positive Genetic
DIA4 YHR011W Probable mitochondrial seryl-tRNA synthetase genetic 1 1 1 Positive Genetic
ABP1 YCR088W Actin-binding protein of the cortical actin cytoskeleton genetic 1 1 1 Negative Genetic
CRZ1 YNL027W Transcription factor, activates transcription of stress response genes genetic 1 1 1 Negative Genetic
AAC3 YBR085W Mitochondrial inner membrane ADP/ATP translocator genetic 1 1 1 Negative Genetic
CNB1 YKL190W Calcineurin B genetic 1 1 1 Negative Genetic
AAT2 YLR027C Cytosolic aspartate aminotransferase involved in nitrogen metabolism genetic 1 1 1 Positive Genetic
CDC9 YDL164C DNA ligase I found in nucleus and mitochondria genetic 1 1 1 Negative Genetic
DOP1 YDR141C Protein involved in vesicular transport at trans-Golgi network (TGN) genetic 1 1 1 Negative Genetic
ATG7 YHR171W Autophagy-related protein and dual specificity member of the E1 family genetic 1 1 1 Synthetic Rescue
ADH4 YGL256W Alcohol dehydrogenase isoenzyme type IV genetic 1 1 1 Positive Genetic
DNL4 YOR005C DNA ligase required for nonhomologous end-joining (NHEJ) genetic 1 1 1 Negative Genetic
CHS1 YNL192W Chitin synthase I genetic 1 1 1 Positive Genetic
DBF2 YGR092W Ser/Thr kinase involved in transcription and stress response genetic 1 1 1 Synthetic Rescue
CSC1 YLR241W Calcium permeable gated cation channel physical 1 1 1 PCA
ARA1 YBR149W NADP+ dependent arabinose dehydrogenase genetic 1 1 1 Negative Genetic
BIR1 YJR089W Subunit of chromosomal passenger complex (CPC) genetic 1 1 1 Positive Genetic
AFG3 YER017C Mitochondrial inner membrane m-AAA protease component genetic 1 1 1 Positive Genetic
ATG1 YGL180W Protein serine/threonine kinase genetic 1 1 1 Synthetic Rescue
ECM31 YBR176W Ketopantoate hydroxymethyltransferase genetic 1 1 1 Negative Genetic
AFT1 YGL071W Transcription factor involved in iron utilization and homeostasis genetic 1 1 1 Negative Genetic
AIM7 YDR063W Protein that interacts with Arp2/3 complex genetic 1 1 1 Negative Genetic
BFR1 YOR198C Component of mRNP complexes associated with polyribosomes physical 1 1 1 Affinity Capture-RNA
YCK2 YNL154C Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform physical 1 1 1 Biochemical Activity
RPN1 YHR027C Non-ATPase base subunit of the 19S RP of the 26S proteasome physical 1 1 1 Affinity Capture-MS
RPN10 YHR200W Proteasome polyubiquitin receptor physical 1 1 1 Affinity Capture-MS
GPI2 YPL076W Protein involved in the synthesis of GlcNAc-PI physical 1 1 1 PCA
YRO2 YBR054W Protein with a putative role in response to acid stress physical 1 1 1 PCA
TAT1 YBR069C Amino acid transporter for valine, leucine, isoleucine, and tyrosine physical 1 1 1 PCA
YPC1 YBR183W Alkaline ceramidase physical 1 1 1 PCA
SSH1 YBR283C Subunit of the Ssh1 translocon complex physical 1 1 1 PCA
MAL31 YBR298C Maltose permease physical 1 1 1 PCA
PMP1 YCR024C-A Regulatory subunit for the plasma membrane H(+)-ATPase Pma1p physical 1 1 1 PCA
FEN2 YCR028C Plasma membrane H+-pantothenate symporter physical 1 1 1 PCA
MCH1 YDL054C Protein with similarity to mammalian monocarboxylate permeases physical 1 1 1 PCA
OST4 YDL232W Subunit of the oligosaccharyltransferase complex of the ER lumen physical 1 1 1 PCA
SUR2 YDR297W Sphinganine C4-hydroxylase physical 1 1 1 PCA
PMT7 YDR307W Putative protein mannosyltransferase similar to Pmt1p physical 1 1 1 PCA
GPI8 YDR331W Catalytic subunit of the ER membrane GPI transamidase complex physical 1 1 1 PCA
ERD1 YDR414C Predicted membrane protein required for lumenal ER protein retention physical 1 1 1 PCA
NHX1 YDR456W Na+/H+ and K+/H+ exchanger physical 1 1 1 PCA
WBP1 YEL002C Beta subunit of the oligosaccharyl transferase glycoprotein complex physical 1 1 1 PCA
PMP2 YEL017C-A Proteolipid associated with plasma membrane H(+)-ATPase (Pma1p) physical 1 1 1 PCA
SHO1 YER118C Transmembrane osmosensor for filamentous growth and HOG pathways physical 1 1 1 PCA
EMP47 YFL048C Integral membrane component of ER-derived COPII-coated vesicles physical 1 1 1 PCA
ERV14 YGL054C COPII-coated vesicle protein physical 1 1 1 PCA
VPS73 YGL104C Mitochondrial protein physical 1 1 1 PCA
EMP24 YGL200C Component of the p24 complex physical 1 1 1 PCA
EMP24 YGL200C Component of the p24 complex genetic 1 1 1 Negative Genetic
ERG25 YGR060W C-4 methyl sterol oxidase physical 1 1 1 PCA
HIP1 YGR191W High-affinity histidine permease physical 1 1 1 PCA
TNA1 YGR260W High affinity nicotinic acid plasma membrane permease physical 1 1 1 PCA
MAL11 YGR289C High-affinity maltose transporter (alpha-glucoside transporter) physical 1 1 1 PCA
YHL042W YHL042W Endoplasmic reticulum protein physical 1 1 1 PCA
VMA16 YHR026W Subunit c'' of the vacuolar ATPase physical 1 1 1 PCA
HXT1 YHR094C Low-affinity glucose transporter of the major facilitator superfamily physical 1 1 1 PCA
ERP5 YHR110W Protein with similarity to Emp24p and Erv25p physical 1 1 1 PCA
EPT1 YHR123W sn-1,2-diacylglycerol ethanolamine- and cholinephosphotranferase physical 1 1 1 PCA
NSG1 YHR133C Protein involved in regulation of sterol biosynthesis physical 1 1 1 PCA
YHR140W YHR140W Endoplasmic reticulum protein physical 1 1 1 PCA
GPI16 YHR188C Subunit of the glycosylphosphatidylinositol transamidase complex physical 1 1 1 PCA
SEC11 YIR022W 18kDa catalytic subunit of the Signal Peptidase Complex (SPC) physical 1 1 1 PCA
SEC11 YIR022W 18kDa catalytic subunit of the Signal Peptidase Complex (SPC) genetic 1 1 1 Negative Genetic
PHO86 YJL117W Endoplasmic reticulum (ER) resident protein physical 1 1 1 PCA
PHO86 YJL117W Endoplasmic reticulum (ER) resident protein genetic 1 1 1 Negative Genetic
HXT8 YJL214W Protein of unknown function with similarity to hexose transporters physical 1 1 1 PCA
VTH2 YJL222W Putative membrane glycoprotein physical 1 1 1 PCA
SPC1 YJR010C-A Subunit of the signal peptidase complex (SPC) physical 1 1 1 PCA
YJR015W YJR015W Putative protein of unknown function physical 1 1 1 PCA
MPH3 YJR160C Alpha-glucoside permease physical 1 1 1 PCA
LAC1 YKL008C Ceramide synthase component physical 1 1 1 PCA
MCD4 YKL165C Protein involved in GPI anchor synthesis physical 1 1 1 PCA
SAC1 YKL212W Phosphatidylinositol phosphate phosphatase physical 1 1 1 PCA
MMM1 YLL006W ER integral membrane protein, ERMES complex subunit physical 1 1 1 PCA
POM33 YLL023C Transmembrane nucleoporin physical 1 1 1 PCA
TPO1 YLL028W Polyamine transporter of the major facilitator superfamily physical 1 1 1 PCA
MMP1 YLL061W High-affinity S-methylmethionine permease physical 1 1 1 PCA
THI73 YLR004C Putative plasma membrane permease physical 1 1 1 PCA
POM34 YLR018C Subunit of the transmembrane ring of the nuclear pore complex (NPC) physical 1 1 1 PCA
SEC61 YLR378C Conserved ER protein translocation channel physical 1 1 1 PCA
GSF2 YML048W Endoplasmic reticulum (ER) localized integral membrane protein physical 1 1 1 PCA
HMG1 YML075C HMG-CoA reductase physical 1 1 1 PCA
PHO84 YML123C High-affinity inorganic phosphate (Pi) transporter physical 1 1 1 PCA
FET3 YMR058W Ferro-O2-oxidoreductase physical 1 1 1 PCA
SWP1 YMR149W Delta subunit of the oligosaccharyl transferase glycoprotein complex physical 1 1 1 PCA
GAS3 YMR215W Putative 1,3-beta-glucanosyltransferase physical 1 1 1 PCA
KEX2 YNL238W Kexin, a subtilisin-like protease (proprotein convertase) physical 1 1 1 PCA
GAS4 YOL132W 1,3-beta-glucanosyltransferase physical 1 1 1 PCA
HXT11 YOL156W Hexose transporter physical 1 1 1 PCA
YPL264C YPL264C Endoplasmic reticulum protein of unknown function physical 1 1 1 PCA
TPO3 YPR156C Polyamine transporter of the major facilitator superfamily physical 1 1 1 PCA
OPT2 YPR194C Oligopeptide transporter physical 1 1 1 PCA
SGE1 YPR198W Plasma membrane multidrug transporter physical 1 1 1 PCA
SRO9 YCL037C Cytoplasmic RNA-binding protein physical 1 1 1 Affinity Capture-RNA
SSB1 YDL229W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Affinity Capture-MS
TEF2 YBR118W Translational elongation factor EF-1 alpha physical 1 1 1 Affinity Capture-MS
SSA2 YLL024C HSP70 family ATP-binding protein physical 1 1 1 Affinity Capture-MS
ULP2 YIL031W Peptidase that deconjugates Smt3/SUMO-1 peptides from proteins physical 1 1 1 PCA
PUF3 YLL013C Protein of the mitochondrial outer surface physical 1 1 1 Affinity Capture-RNA
PDR5 YOR153W Plasma membrane ATP-binding cassette (ABC) transporter physical 1 1 1 PCA
HSP104 YLL026W Disaggregase physical 1 1 1 Affinity Capture-MS
TOM1 YDR457W E3 ubiquitin ligase of the hect-domain class physical 1 1 1 Affinity Capture-MS
SND2 YLR065C Protein involved in SRP-independent targeting of substrates to the ER physical 1 1 1 Affinity Capture-MS
SND3 YBR106W Involved in SRP-independent protein targeting to the ER physical 1 1 1 Affinity Capture-MS
SND3 YBR106W Involved in SRP-independent protein targeting to the ER genetic 1 1 1 Negative Genetic
KRR1 YCL059C Nucleolar protein required for rRNA synthesis and ribosomal assembly physical 1 1 1 Affinity Capture-MS
UTP10 YJL109C Nucleolar protein physical 1 1 1 Affinity Capture-MS
MPS3 YJL019W Nuclear envelope protein physical 1 1 1 Affinity Capture-MS
RET1 YOR207C Second-largest subunit of RNA polymerase III physical 1 1 1 Affinity Capture-MS
TOM22 YNL131W Component of the TOM (Translocase of Outer Membrane) complex physical 1 1 1 Affinity Capture-MS
ERG6 YML008C Delta(24)-sterol C-methyltransferase genetic 1 1 1 Synthetic Lethality
STT4 YLR305C Phosphatidylinositol-4-kinase genetic 1 1 1 Synthetic Lethality
UPC2 YDR213W Sterol regulatory element binding protein genetic 1 1 1 Synthetic Rescue
RAD3 YER171W 5' to 3' DNA helicase genetic 1 1 1 Dosage Rescue
SNC2 YOR327C Vesicle membrane receptor protein (v-SNARE) genetic 1 1 1 Synthetic Rescue
YVC1 YOR087W Vacuolar cation channel genetic 1 1 1 Phenotypic Suppression
SEC14 YMR079W Phosphatidylinositol/phosphatidylcholine transfer protein genetic 1 1 1 Synthetic Growth Defect
TEL1 YBL088C Protein kinase primarily involved in telomere length regulation genetic 1 1 1 Phenotypic Enhancement
RAD50 YNL250W Subunit of MRX complex with Mre11p and Xrs2p genetic 1 1 1 Phenotypic Enhancement
EST1 YLR233C TLC1 RNA-associated factor involved in telomere length regulation genetic 1 1 1 Phenotypic Enhancement
VMA1 YDL185W Subunit A of the V1 peripheral membrane domain of V-ATPase genetic 1 1 1 Synthetic Growth Defect
UFD1 YGR048W Substrate-recruiting cofactor of the Cdc48p-Npl4p-Ufd1p segregase genetic 1 1 1 Phenotypic Enhancement
SLY1 YDR189W Hydrophilic protein involved in ER/Golgi vesicle trafficking genetic 1 1 1 Negative Genetic
TRP2 YER090W Anthranilate synthase genetic 1 1 1 Negative Genetic
LEU1 YGL009C Isopropylmalate isomerase genetic 1 1 1 Negative Genetic
TPO5 YKL174C Protein involved in excretion of putrescine and spermidine genetic 1 1 1 Negative Genetic
FRA1 YLL029W Protein involved in negative regulation of iron regulon transcription genetic 1 1 1 Negative Genetic
MCP1 YOR228C Mitochondrial protein of unknown function involved in lipid homeostas genetic 1 1 1 Negative Genetic
SEC63 YOR254C Essential subunit of Sec63 complex genetic 1 1 1 Negative Genetic
SUT2 YPR009W Zn2Cys6 family transcription factor genetic 1 1 1 Positive Genetic
KAR2 YJL034W ATPase involved in protein import into the ER genetic 1 1 1 Positive Genetic
HIS3 YOR202W Imidazoleglycerol-phosphate dehydratase genetic 1 1 1 Phenotypic Suppression
VMA21 YGR105W Integral membrane protein required for V-ATPase function genetic 1 1 1 Synthetic Growth Defect
VOA1 YGR106C ER protein that functions in assembly of the V0 sector of V-ATPase genetic 1 1 1 Synthetic Growth Defect
GRX5 YPL059W Glutathione-dependent oxidoreductase genetic 1 1 1 Positive Genetic
HEM2 YGL040C Aminolevulinate dehydratase genetic 1 1 1 Negative Genetic
RIB3 YDR487C 3,4-dihydroxy-2-butanone-4-phosphate synthase (DHBP synthase) genetic 1 1 1 Negative Genetic
PHO87 YCR037C Low-affinity inorganic phosphate (Pi) transporter genetic 1 1 1 Positive Genetic
RIB2 YOL066C Bifunctional DRAP deaminase tRNA:pseudouridine synthase genetic 1 1 1 Negative Genetic
ORT1 YOR130C Ornithine transporter of the mitochondrial inner membrane genetic 1 1 1 Positive Genetic
SAM3 YPL274W High-affinity S-adenosylmethionine permease genetic 1 1 1 Positive Genetic
YUR1 YJL139C Mannosyltransferase involved in protein N-glycosylation genetic 1 1 1 Negative Genetic
FBA1 YKL060C Fructose 1,6-bisphosphate aldolase genetic 1 1 1 Negative Genetic
SPE1 YKL184W Ornithine decarboxylase genetic 1 1 1 Positive Genetic
GFA1 YKL104C Glutamine-fructose-6-phosphate amidotransferase genetic 1 1 1 Negative Genetic
FMS1 YMR020W Polyamine oxidase genetic 1 1 1 Negative Genetic
ILV6 YCL009C Regulatory subunit of acetolactate synthase genetic 1 1 1 Positive Genetic
PGM2 YMR105C Phosphoglucomutase genetic 1 1 1 Positive Genetic
POS5 YPL188W Mitochondrial NADH kinase genetic 1 1 1 Positive Genetic
PFK1 YGR240C Alpha subunit of heterooctameric phosphofructokinase genetic 1 1 1 Positive Genetic
SDH2 YLL041C Iron-sulfur protein subunit of succinate dehydrogenase genetic 1 1 1 Negative Genetic
TPS2 YDR074W Phosphatase subunit of the trehalose-6-P synthase/phosphatase complex genetic 1 1 1 Positive Genetic
GLN1 YPR035W Glutamine synthetase (GS) genetic 1 1 1 Negative Genetic
PRO2 YOR323C Gamma-glutamyl phosphate reductase genetic 1 1 1 Positive Genetic
MET7 YOR241W Folylpolyglutamate synthetase genetic 1 1 1 Positive Genetic
RBK1 YCR036W Ribokinase, phosphorylates ribose to ribose-5-phosphate genetic 1 1 1 Positive Genetic
NRK1 YNL129W Nicotinamide riboside kinase genetic 1 1 1 Positive Genetic
PAN6 YIL145C Pantothenate synthase genetic 1 1 1 Negative Genetic
PDC1 YLR044C Major of three pyruvate decarboxylase isozymes genetic 1 1 1 Positive Genetic
NDE2 YDL085W Mitochondrial external NADH dehydrogenase genetic 1 1 1 Negative Genetic
YML082W YML082W Putative protein predicted to have carbon-sulfur lyase activity genetic 1 1 1 Positive Genetic
SDH9 YJL045W Minor succinate dehydrogenase isozyme genetic 1 1 1 Negative Genetic
ILS1 YBL076C Cytoplasmic isoleucine-tRNA synthetase genetic 1 1 1 Negative Genetic
HOM6 YJR139C Homoserine dehydrogenase (L-homoserine:NADP oxidoreductase) genetic 1 1 1 Negative Genetic
IDI1 YPL117C Isopentenyl diphosphate:dimethylallyl diphosphate isomerase genetic 1 1 1 Negative Genetic
SPE2 YOL052C S-adenosylmethionine decarboxylase genetic 1 1 1 Negative Genetic
NCP1 YHR042W NADP-cytochrome P450 reductase genetic 1 1 1 Negative Genetic
OPI3 YJR073C Methylene-fatty-acyl-phospholipid synthase genetic 1 1 1 Positive Genetic
HXK2 YGL253W Hexokinase isoenzyme 2 genetic 1 1 1 Positive Genetic
GLK1 YCL040W Glucokinase genetic 1 1 1 Negative Genetic
HEM3 YDL205C Porphobilinogen deaminase genetic 1 1 1 Negative Genetic
OLE1 YGL055W Delta(9) fatty acid desaturase genetic 1 1 1 Negative Genetic
TPS1 YBR126C Synthase subunit of trehalose-6-P synthase/phosphatase complex genetic 1 1 1 Positive Genetic
OAR1 YKL055C Mitochondrial 3-oxoacyl-[acyl-carrier-protein] reductase genetic 1 1 1 Positive Genetic
IDP1 YDL066W Mitochondrial NADP-specific isocitrate dehydrogenase genetic 1 1 1 Negative Genetic
GSH1 YJL101C Gamma glutamylcysteine synthetase genetic 1 1 1 Negative Genetic
MET6 YER091C Cobalamin-independent methionine synthase genetic 1 1 1 Positive Genetic
HXT6 YDR343C High-affinity glucose transporter genetic 1 1 1 Negative Genetic
YMR226C YMR226C NADP(+)-dependent serine dehydrogenase and carbonyl reductase genetic 1 1 1 Negative Genetic
SDT1 YGL224C Pyrimidine nucleotidase genetic 1 1 1 Negative Genetic
MDM10 YAL010C Subunit of both the ERMES and the SAM complex genetic 1 1 1 Positive Genetic
FUS3 YBL016W Mitogen-activated serine/threonine protein kinase involved in mating genetic 1 1 1 Positive Genetic
PIM1 YBL022C ATP-dependent Lon protease genetic 1 1 1 Negative Genetic
PIN4 YBL051C Protein involved in G2/M phase progression and response to DNA damage genetic 1 1 1 Positive Genetic
FZO1 YBR179C Mitofusin, protein involved in mitochondrial outer membrane fusion genetic 1 1 1 Positive Genetic
STE50 YCL032W Adaptor protein for various signaling pathways genetic 1 1 1 Negative Genetic
RPS11A YDR025W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
UGO1 YDR470C Outer membrane component of the mitochondrial fusion machinery genetic 1 1 1 Positive Genetic
ISC1 YER019W Inositol phosphosphingolipid phospholipase C genetic 1 1 1 Positive Genetic
MDJ1 YFL016C Co-chaperone that stimulates HSP70 protein Ssc1p ATPase activity genetic 1 1 1 Positive Genetic
RPO41 YFL036W Mitochondrial RNA polymerase genetic 1 1 1 Positive Genetic
UBP6 YFR010W Ubiquitin-specific protease genetic 1 1 1 Negative Genetic
GET1 YGL020C Subunit of the GET complex genetic 1 1 1 Positive Genetic
PIB2 YGL023C Phosphatidylinositol 3-phosphate binding protein genetic 1 1 1 Positive Genetic
VRG4 YGL225W Golgi GDP-mannose transporter genetic 1 1 1 Negative Genetic
KAR3 YPR141C Minus-end-directed microtubule motor genetic 1 1 1 Synthetic Rescue
MDL2 YPL270W Mitochondrial inner membrane half-type ABC transporter genetic 1 1 1 Synthetic Rescue
PAT1 YCR077C Deadenylation-dependent mRNA-decapping factor genetic 1 1 1 Synthetic Rescue
RPL19B YBL027W Ribosomal 60S subunit protein L19B genetic 1 1 1 Synthetic Rescue
SWS2 YNL081C Putative mitochondrial ribosomal protein of the small subunit genetic 1 1 1 Synthetic Rescue
THR1 YHR025W Homoserine kinase genetic 1 1 1 Synthetic Rescue
YJR120W YJR120W Protein of unknown function genetic 1 1 1 Synthetic Rescue
PHB1 YGR132C Subunit of the prohibitin complex (Phb1p-Phb2p) genetic 1 1 1 Positive Genetic
PHB2 YGR231C Subunit of the prohibitin complex (Phb1p-Phb2p) genetic 1 1 1 Positive Genetic
ZUO1 YGR285C Ribosome-associated chaperone genetic 1 1 1 Positive Genetic
GEP4 YHR100C Mitochondrial phosphatidylglycerophosphatase (PGP phosphatase) genetic 1 1 1 Positive Genetic
SSM4 YIL030C Membrane-embedded ubiquitin-protein ligase and retrotranslocase genetic 1 1 1 Negative Genetic
PET130 YJL023C Protein of unknown function genetic 1 1 1 Positive Genetic
PTK2 YJR059W Serine/threonine protein kinase genetic 1 1 1 Positive Genetic
MSC1 YML128C Protein of unknown function genetic 1 1 1 Positive Genetic
SAP30 YMR263W Component of Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
MDM12 YOL009C Mitochondrial outer membrane protein, ERMES complex subunit genetic 1 1 1 Negative Genetic
SLG1 YOR008C Sensor-transducer of the stress-activated PKC1-MPK1 kinase pathway genetic 1 1 1 Negative Genetic
NOP4 YPL043W Nucleolar protein genetic 1 1 1 Negative Genetic
IFA38 YBR159W Microsomal beta-keto-reductase genetic 1 1 1 Synthetic Growth Defect
HFA1 YMR207C Mitochondrial acetyl-coenzyme A carboxylase genetic 1 1 1 Synthetic Rescue
LAT1 YNL071W Dihydrolipoamide acetyltransferase component (E2) of the PDC genetic 1 1 1 Synthetic Rescue
LIP2 YLR239C Lipoyl ligase genetic 1 1 1 Synthetic Rescue
LIP5 YOR196C Protein involved in biosynthesis of the coenzyme lipoic acid genetic 1 1 1 Synthetic Rescue
MCT1 YOR221C Predicted malonyl-CoA:ACP transferase genetic 1 1 1 Synthetic Rescue
PDA1 YER178W E1 alpha subunit of the pyruvate dehydrogenase (PDH) complex genetic 1 1 1 Synthetic Rescue
TAZ1 YPR140W Lyso-phosphatidylcholine acyltransferase genetic 1 1 1 Synthetic Rescue
SAM37 YMR060C Component of the Sorting and Assembly Machinery (SAM) complex genetic 1 1 1 Synthetic Rescue
PFK2 YMR205C Beta subunit of heterooctameric phosphofructokinase genetic 1 1 1 Synthetic Rescue
HMT1 YBR034C Nuclear SAM-dependent mono- and asymmetric methyltransferase genetic 1 1 1 Negative Genetic
SEC13 YLR208W Structural component of 3 complexes genetic 1 1 1 Synthetic Growth Defect
TTI1 YKL033W Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Positive Genetic
YOR1 YGR281W Plasma membrane ATP-binding cassette (ABC) transporter genetic 1 1 1 Negative Genetic
LST8 YNL006W Protein required for the transport of Gap1p genetic 1 1 1 Negative Genetic
LEM3 YNL323W Membrane protein of the plasma membrane and ER genetic 1 1 1 Negative Genetic
YPS7 YDR349C Putative GPI-anchored aspartic protease genetic 1 1 1 Negative Genetic
MNL2 YLR057W Putative mannosidase involved in ER-associated protein degradation genetic 1 1 1 Negative Genetic
GPI11 YDR302W ER membrane protein involved in a late step of GPI anchor assembly genetic 1 1 1 Positive Genetic
SLA1 YBL007C Cytoskeletal protein binding protein genetic 1 1 1 Negative Genetic
MNN2 YBR015C Alpha-1,2-mannosyltransferase genetic 1 1 1 Negative Genetic
HAC1 YFL031W Basic leucine zipper (bZIP) transcription factor (ATF/CREB1 homolog) genetic 1 1 1 Negative Genetic
IRE1 YHR079C Serine-threonine kinase and endoribonuclease genetic 1 1 1 Negative Genetic
VPS24 YKL041W One of four subunits of the ESCRT-III complex genetic 1 1 1 Negative Genetic
IWR1 YDL115C RNA polymerase II transport factor, conserved from yeast to humans genetic 1 1 1 Positive Genetic
PSD1 YNL169C Phosphatidylserine decarboxylase of the mitochondrial inner membrane genetic 1 1 1 Positive Genetic
RET2 YFR051C Delta subunit of the coatomer complex (COPI) genetic 1 1 1 Negative Genetic
TLG2 YOL018C Syntaxin-like t-SNARE genetic 1 1 1 Positive Genetic
SPT14 YPL175W UDP-glycosyltransferase subunit of the GPI-GnT complex genetic 1 1 1 Negative Genetic
VPS60 YDR486C Protein involved in late endosome to vacuole transport genetic 1 1 1 Negative Genetic
VPS1 YKR001C Dynamin-like GTPase required for vacuolar sorting genetic 1 1 1 Negative Genetic
VPS5 YOR069W Nexin-1 homolog genetic 1 1 1 Negative Genetic
FRQ1 YDR373W N-myristoylated calcium-binding protein genetic 1 1 1 Negative Genetic
ERG26 YGL001C C-3 sterol dehydrogenase genetic 1 1 1 Negative Genetic
ERV46 YAL042W Protein localized to COPII-coated vesicles genetic 1 1 1 Negative Genetic
FAA1 YOR317W Long chain fatty acyl-CoA synthetase genetic 1 1 1 Negative Genetic
RBL2 YOR265W Protein involved in microtubule morphogenesis genetic 1 1 1 Negative Genetic
SSO2 YMR183C Plasma membrane t-SNARE genetic 1 1 1 Negative Genetic
KES1 YPL145C Sterol/phosphatidylinositol-4-phosphate (PI(4)P) exchanger genetic 1 1 1 Negative Genetic
MKC7 YDR144C GPI-anchored aspartyl protease genetic 1 1 1 Negative Genetic
VPS55 YJR044C Late endosomal protein involved in late endosome to vacuole transport genetic 1 1 1 Negative Genetic
SCS2 YER120W Integral ER membrane protein, regulates phospholipid metabolism genetic 1 1 1 Negative Genetic
RTT107 YHR154W BRCA1 C-terminal domain protein needed for recovery from DNA damage genetic 1 1 1 Negative Genetic
SLX4 YLR135W Endonuclease involved in processing DNA genetic 1 1 1 Negative Genetic
KNS1 YLL019C Protein kinase involved in negative regulation of PolIII transcription genetic 1 1 1 Synthetic Growth Defect
RRP43 YCR035C Exosome non-catalytic core component genetic 1 1 1 Positive Genetic
TIM22 YDL217C Essential core component of mitochondrial TIM22 complex genetic 1 1 1 Positive Genetic
MMS21 YEL019C Highly conserved SUMO E3 ligase subunit of SMC5-SMC6 complex genetic 1 1 1 Positive Genetic
NUP116 YMR047C FG-nucleoporin component of central core of the nuclear pore complex genetic 1 1 1 Positive Genetic
PRP24 YMR268C Splicing factor that reanneals snRNPs during spliceosome recycling genetic 1 1 1 Positive Genetic
SRV2 YNL138W CAP (cyclase-associated protein) genetic 1 1 1 Positive Genetic
MTR10 YOR160W Nuclear import receptor genetic 1 1 1 Positive Genetic
MRPL32 YCR003W Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Positive Genetic
NPP1 YCR026C Nucleotide pyrophosphatase/phosphodiesterase genetic 1 1 1 Positive Genetic
SNT1 YCR033W Set3C histone deacetylase scaffold genetic 1 1 1 Positive Genetic
RGT2 YDL138W Plasma membrane high glucose sensor that regulates glucose transport genetic 1 1 1 Positive Genetic
GCN4 YEL009C bZIP transcriptional activator of amino acid biosynthetic genes genetic 1 1 1 Positive Genetic
VMA8 YEL051W Subunit D of the V1 peripheral membrane domain of V-ATPase genetic 1 1 1 Positive Genetic
YPT31 YER031C Rab family GTPase genetic 1 1 1 Positive Genetic
SEC28 YIL076W Epsilon-COP subunit of the coatomer genetic 1 1 1 Positive Genetic
RPA49 YNL248C RNA polymerase I subunit A49 genetic 1 1 1 Positive Genetic
TRS33 YOR115C Core component of TRAPP complexes I, II and IV genetic 1 1 1 Positive Genetic
MRPL40 YPL173W Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Positive Genetic
POL30 YBR088C Proliferating cell nuclear antigen (PCNA) genetic 1 1 1 Negative Genetic
MEC1 YBR136W Genome integrity checkpoint protein and PI kinase superfamily member genetic 1 1 1 Negative Genetic
MAK5 YBR142W Essential nucleolar protein genetic 1 1 1 Negative Genetic
HEM13 YDR044W Coproporphyrinogen III oxidase genetic 1 1 1 Negative Genetic
LCB2 YDR062W Component of serine palmitoyltransferase genetic 1 1 1 Negative Genetic
SSS1 YDR086C Subunit of the Sec61p translocation complex (Sec61p-Sss1p-Sbh1p) genetic 1 1 1 Negative Genetic
PMI40 YER003C Mannose-6-phosphate isomerase genetic 1 1 1 Negative Genetic
MOB2 YFL034C-B Activator of Cbk1p kinase genetic 1 1 1 Negative Genetic
SCL1 YGL011C Alpha 1 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
TIP20 YGL145W Peripheral membrane protein required for COPI vesicle fusion to the ER genetic 1 1 1 Negative Genetic
SNU71 YGR013W Component of U1 snRNP required for mRNA splicing via spliceosome genetic 1 1 1 Negative Genetic
TYS1 YGR185C Cytoplasmic tyrosyl-tRNA synthetase genetic 1 1 1 Negative Genetic
NOP19 YGR251W Ribosome biogenesis factor genetic 1 1 1 Negative Genetic
ERG7 YHR072W Lanosterol synthase genetic 1 1 1 Negative Genetic
ERG9 YHR190W Farnesyl-diphosphate farnesyl transferase (squalene synthase) genetic 1 1 1 Negative Genetic
RRN7 YJL025W Component of the core factor (CF) rDNA transcription factor complex genetic 1 1 1 Negative Genetic
UBA1 YKL210W Ubiquitin activating enzyme (E1) genetic 1 1 1 Negative Genetic
SSL1 YLR005W Subunit of the core form of RNA polymerase transcription factor TFIIH genetic 1 1 1 Negative Genetic
RSC9 YML127W Component of the RSC chromatin remodeling complex genetic 1 1 1 Negative Genetic
VTI1 YMR197C Protein involved in cis-Golgi membrane traffic genetic 1 1 1 Negative Genetic
ROT1 YMR200W Molecular chaperone involved in protein folding in ER genetic 1 1 1 Negative Genetic
GPI15 YNL038W Protein involved in the synthesis of GlcNAc-PI genetic 1 1 1 Negative Genetic
INN1 YNL152W Essential protein that associates with contractile actomyosin ring genetic 1 1 1 Negative Genetic
RPS3 YNL178W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
PBR1 YNL181W Putative oxidoreductase genetic 1 1 1 Negative Genetic
NAR1 YNL240C Subunit of the cytosolic iron-sulfur (FeS) protein assembly machinery genetic 1 1 1 Negative Genetic
LTO1 YNL260C Substrate-specific adaptor protein involved in apo-Rli1p maturation genetic 1 1 1 Negative Genetic
SEC21 YNL287W Gamma subunit of coatomer genetic 1 1 1 Negative Genetic
TIM23 YNR017W Essential component of the TIM23 complex genetic 1 1 1 Negative Genetic
OST2 YOR103C Epsilon subunit of the oligosaccharyltransferase complex genetic 1 1 1 Negative Genetic
THI80 YOR143C Thiamine pyrophosphokinase genetic 1 1 1 Negative Genetic
PUP1 YOR157C Beta 2 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
GLN4 YOR168W Glutamine tRNA synthetase genetic 1 1 1 Negative Genetic
RPN8 YOR261C Essential non-ATPase regulatory subunit of the 26S proteasome genetic 1 1 1 Negative Genetic
RET3 YPL010W Zeta subunit of the coatomer complex (COPI) genetic 1 1 1 Negative Genetic
ULP1 YPL020C Protease that specifically cleaves Smt3p protein conjugates genetic 1 1 1 Negative Genetic
TIM50 YPL063W Essential component of the TIM23 complex genetic 1 1 1 Negative Genetic
SEC62 YPL094C Essential subunit of Sec63 complex genetic 1 1 1 Negative Genetic
RPN7 YPR108W Essential non-ATPase regulatory subunit of the 26S proteasome genetic 1 1 1 Negative Genetic
SEC23 YPR181C GTPase-activating protein, stimulates the GTPase activity of Sar1p genetic 1 1 1 Negative Genetic
SCS22 YBL091C-A Protein involved in regulation of phospholipid metabolism genetic 1 1 1 Negative Genetic
RGD1 YBR260C GTPase-activating protein (RhoGAP) for Rho3p and Rho4p genetic 1 1 1 Negative Genetic
MRPL27 YBR282W Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
KGD2 YDR148C Dihydrolipoyl transsuccinylase genetic 1 1 1 Negative Genetic
TRP4 YDR354W Anthranilate phosphoribosyl transferase genetic 1 1 1 Negative Genetic
EUG1 YDR518W Protein disulfide isomerase of the endoplasmic reticulum lumen genetic 1 1 1 Negative Genetic
SDD1 YEL057C Protein of unknown function genetic 1 1 1 Negative Genetic
HPA3 YEL066W D-Amino acid N-acetyltransferase that detoxifies D-amino acids genetic 1 1 1 Negative Genetic
HXT13 YEL069C Putative transmembrane polyol transporter genetic 1 1 1 Negative Genetic
FCY22 YER060W-A Putative purine-cytosine permease genetic 1 1 1 Negative Genetic
UBP5 YER144C Putative ubiquitin-specific protease genetic 1 1 1 Negative Genetic
RPH1 YER169W JmjC domain-containing histone demethylase genetic 1 1 1 Negative Genetic
MPC1 YGL080W Highly conserved subunit of mitochondrial pyruvate carrier (MPC) genetic 1 1 1 Negative Genetic
MRF1 YGL143C Mitochondrial translation release factor genetic 1 1 1 Negative Genetic
YGL185C YGL185C Putative protein with sequence similar to hydroxyacid dehydrogenases genetic 1 1 1 Negative Genetic
TIM21 YGR033C Nonessential component of the TIM23 complex genetic 1 1 1 Negative Genetic
NEM1 YHR004C Probable catalytic subunit of Nem1p-Spo7p phosphatase holoenzyme genetic 1 1 1 Negative Genetic
NBL1 YHR199C-A Subunit of the conserved chromosomal passenger complex (CPC) genetic 1 1 1 Negative Genetic
YHR213W YHR213W Pseudogenic fragment with similarity to flocculins genetic 1 1 1 Negative Genetic
YIL102C YIL102C Putative protein of unknown function genetic 1 1 1 Negative Genetic
PFK26 YIL107C 6-phosphofructo-2-kinase genetic 1 1 1 Negative Genetic
RRT14 YIL127C Putative protein of unknown function genetic 1 1 1 Negative Genetic
NRE1 YIR035C Putative cytoplasmic short-chain dehydrogenase/reductase genetic 1 1 1 Negative Genetic
GEF1 YJR040W Voltage-gated chloride channel genetic 1 1 1 Negative Genetic
LIA1 YJR070C Deoxyhypusine hydroxylase genetic 1 1 1 Negative Genetic
SAP190 YKR028W Protein that forms a complex with the Sit4p protein phosphatase genetic 1 1 1 Negative Genetic
SKG1 YKR100C Transmembrane protein with a role in cell wall polymer composition genetic 1 1 1 Negative Genetic
PSR2 YLR019W Putative plasma membrane phosphatase genetic 1 1 1 Negative Genetic
IES3 YLR052W Subunit of the INO80 chromatin remodeling complex genetic 1 1 1 Negative Genetic
EMP46 YLR080W Integral membrane component of ER-derived COPII-coated vesicles genetic 1 1 1 Negative Genetic
ORM1 YGR038W Protein that mediates sphingolipid homeostasis genetic 1 1 1 Dosage Rescue
YML054C-A YML054C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
EPO1 YMR124W Protein involved in septin-ER tethering genetic 1 1 1 Negative Genetic
LDO16 YMR148W Protein of unknown function with possible role in spore wall assembly genetic 1 1 1 Negative Genetic
ICY1 YMR195W Protein of unknown function genetic 1 1 1 Negative Genetic
SCH9 YHR205W AGC family protein kinase genetic 1 1 1 Synthetic Growth Defect
RCE1 YMR274C Type II CAAX prenyl protease genetic 1 1 1 Negative Genetic
YMR295C YMR295C Protein of unknown function that associates with ribosomes genetic 1 1 1 Negative Genetic
LEU4 YNL104C Alpha-isopropylmalate synthase (2-isopropylmalate synthase) genetic 1 1 1 Negative Genetic
URE2 YNL229C Nitrogen catabolite repression transcriptional regulator genetic 1 1 1 Negative Genetic
LAP3 YNL239W Cysteine aminopeptidase with homocysteine-thiolactonase activity genetic 1 1 1 Negative Genetic
TOS6 YNL300W Glycosylphosphatidylinositol-dependent cell wall protein genetic 1 1 1 Negative Genetic
YPT11 YNL304W Rab GTPase genetic 1 1 1 Negative Genetic
PHO91 YNR013C Low-affinity vacuolar phosphate transporter genetic 1 1 1 Negative Genetic
IMA2 YOL157C Isomaltase (alpha-1,6-glucosidase/alpha-methylglucosidase) genetic 1 1 1 Negative Genetic
IES4 YOR189W Component of the INO80 chromatiin remodeling complex genetic 1 1 1 Negative Genetic
VTC3 YPL019C Regulatory subunit of the vacuolar transporter chaperone (VTC) complex genetic 1 1 1 Negative Genetic
TRM44 YPL030W tRNA(Ser) Um(44) 2'-O-methyltransferase genetic 1 1 1 Negative Genetic
MRX11 YPL041C Protein that associates with mitochondrial ribosome genetic 1 1 1 Negative Genetic
SPO19 YPL130W Meiosis-specific prospore protein genetic 1 1 1 Negative Genetic
LEA1 YPL213W Component of U2 snRNP complex genetic 1 1 1 Negative Genetic
HOB2 YPR117W Protein with structural similarity to lipid transport protein Vps13p genetic 1 1 1 Negative Genetic
YNG2 YHR090C Subunit of NuA4, an essential histone acetyltransferase complex genetic 1 1 1 Positive Genetic
ESP1 YGR098C Separase/separin, a caspase-like cysteine protease genetic 1 1 1 Synthetic Growth Defect
VPS3 YDR495C Component of CORVET membrane tethering complex genetic 1 1 1 Synthetic Growth Defect
VPS8 YAL002W Membrane-binding component of the CORVET complex genetic 1 1 1 Synthetic Growth Defect
VPS41 YDR080W Subunit of the HOPS endocytic tethering complex genetic 1 1 1 Synthetic Growth Defect
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p genetic 1 1 1 Synthetic Growth Defect
TUB4 YLR212C Gamma-tubulin genetic 1 1 1 Synthetic Rescue
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 1 1 1 Positive Genetic
CSG2 YBR036C Endoplasmic reticulum membrane protein physical 1 1 1 PCA
ARG82 YDR173C Inositol polyphosphate multikinase (IPMK) genetic 1 1 1 Synthetic Rescue
CHS3 YBR023C Chitin synthase III genetic 1 1 1 Negative Genetic
ATP1 YBL099W Alpha subunit of the F1 sector of mitochondrial F1F0 ATP synthase genetic 1 1 1 Positive Genetic
ALG5 YPL227C UDP-glucose:dolichyl-phosphate glucosyltransferase genetic 1 1 1 Negative Genetic
ASH1 YKL185W Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
AUR1 YKL004W Phosphatidylinositol:ceramide phosphoinositol transferase genetic 1 1 1 Synthetic Rescue
BSD2 YBR290W Heavy metal ion homeostasis protein physical 1 1 1 PCA
BSD2 YBR290W Heavy metal ion homeostasis protein genetic 1 1 1 Positive Genetic
ARL3 YPL051W ARF-like small GTPase of the RAS superfamily genetic 1 1 1 Negative Genetic
DBP6 YNR038W Essential protein involved in ribosome biogenesis genetic 1 1 1 Positive Genetic
BTS1 YPL069C Geranylgeranyl diphosphate synthase (GGPPS) genetic 1 1 1 Positive Genetic
ALG1 YBR110W Mannosyltransferase physical 1 1 1 PCA
COQ3 YOL096C O-methyltransferase genetic 1 1 1 Negative Genetic
EGT2 YNL327W Glycosylphosphatidylinositol (GPI)-anchored cell wall endoglucanase genetic 1 1 1 Negative Genetic
CAN1 YEL063C Plasma membrane arginine permease physical 1 1 1 PCA
BAP3 YDR046C Amino acid permease physical 1 1 1 PCA
CFD1 YIL003W Highly conserved iron-sulfur cluster binding protein genetic 1 1 1 Negative Genetic
ATP15 YPL271W Epsilon subunit of the F1 sector of mitochondrial F1F0 ATP synthase genetic 1 1 1 Positive Genetic
BRL1 YHR036W Essential nuclear envelope/ER integral membrane protein genetic 1 1 1 Synthetic Lethality
ACB1 YGR037C Acyl-CoA-binding protein genetic 1 1 1 Positive Genetic
ALD6 YPL061W Cytosolic aldehyde dehydrogenase genetic 1 1 1 Positive Genetic
CTP1 YBR291C Mitochondrial inner membrane citrate transporter genetic 1 1 1 Positive Genetic
APS1 YLR170C Small subunit of the clathrin-associated adaptor complex AP-1 genetic 1 1 1 Negative Genetic
ANY1 YMR010W Protein involved in phospholipid flippase function genetic 1 1 1 Negative Genetic
ALT1 YLR089C Alanine transaminase (glutamic pyruvic transaminase) genetic 1 1 1 Negative Genetic
CAB1 YDR531W Pantothenate kinase, ATP:D-pantothenate 4'-phosphotransferase genetic 1 1 1 Negative Genetic
ECM22 YLR228C Sterol regulatory element binding protein genetic 1 1 1 Synthetic Rescue
CHS7 YHR142W Protein of unknown function physical 1 1 1 PCA
CHS7 YHR142W Protein of unknown function genetic 1 1 1 Negative Genetic
ALG6 YOR002W ER-luminal alpha 1,3 glucosyltransferase genetic 1 1 1 Negative Genetic
COS4 YFL062W Endosomal protein involved in turnover of plasma membrane proteins physical 1 1 1 PCA
CDC50 YCR094W Endosomal protein that interacts with phospholipid flippase Drs2p genetic 1 1 1 Positive Genetic
CHO2 YGR157W Phosphatidylethanolamine methyltransferase (PEMT) genetic 1 1 1 Positive Genetic
COS8 YHL048W Endosomal protein involved in turnover of plasma membrane proteins physical 1 1 1 PCA
COS8 YHL048W Endosomal protein involved in turnover of plasma membrane proteins genetic 1 1 1 Synthetic Rescue
DCW1 YKL046C Putative mannosidase genetic 1 1 1 Negative Genetic
BRR6 YGL247W Essential nuclear envelope integral membrane protein genetic 1 1 1 Synthetic Lethality
AVL9 YLR114C Conserved protein involved in exocytic transport from the Golgi genetic 1 1 1 Negative Genetic
ALG9 YNL219C Mannosyltransferase, involved in N-linked glycosylation genetic 1 1 1 Negative Genetic
ELO1 YJL196C Elongase I, medium-chain acyl elongase physical 1 1 1 PCA
AFG1 YEL052W Protein that may act as a chaperone for cytochrome c oxidase subunits genetic 1 1 1 Negative Genetic
COS6 YGR295C Endosomal protein involved in turnover of plasma membrane proteins physical 1 1 1 PCA
AGP1 YCL025C Broad-specificity, low-affinity amino acid permease physical 1 1 1 PCA
ALG11 YNL048W Alpha-1,2-mannosyltransferase physical 1 1 1 PCA
ALG11 YNL048W Alpha-1,2-mannosyltransferase genetic 1 1 1 Negative Genetic
ECT1 YGR007W Ethanolamine-phosphate cytidylyltransferase genetic 1 1 1 Negative Genetic
ECM14 YHR132C Conserved fungal protein with similarity to zinc carboxypeptidases genetic 1 1 1 Negative Genetic