Standard name Systematic name Name description Description
OPT2 YPR194C Oligopeptide transporter Oligopeptide transporter; localized to peroxisomes and affects glutathione redox homeostasis; also localizes to the plasma membrane (PM) and to the late Golgi, and has a role in maintenance of lipid asymmetry between the inner and outer leaflets of the PM; member of the OPT family, with potential orthologs in S. pombe and C. albicans; also plays a role in formation of mature vacuoles and in polarized cell growth
Visualize the interactome of OPT2
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
no data no data no data

GFP localization & abundance

GFP localization GFP abundance
no data no data

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
OPT2 0 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
LEM3 YNL323W Membrane protein of the plasma membrane and ER genetic 5 5 1 Synthetic Growth Defect, Dosage Rescue, Phenotypic Enhancement, Phenotypic Suppression, Synthetic Rescue
PDA1 YER178W E1 alpha subunit of the pyruvate dehydrogenase (PDH) complex genetic 4 2 3 Negative Genetic, Negative Genetic, Synthetic Lethality, Negative Genetic
MGR2 YPL098C Subunit of the TIM23 translocase complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
FKH1 YIL131C Forkhead family transcription factor regulation 2 2 2 chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments
FKH2 YNL068C Forkhead family transcription factor regulation 2 2 2 chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments
BMS1 YPL217C GTPase required for ribosomal subunit synthesis and rRNA processing genetic 2 1 2 Negative Genetic, Negative Genetic
RPS24B YIL069C Protein component of the small (40S) ribosomal subunit genetic 2 1 2 Negative Genetic, Negative Genetic
RIM21 YNL294C pH sensor molecule, component of the RIM101 pathway genetic 2 2 1 Dosage Rescue, Phenotypic Suppression
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
MET32 YDR253C Zinc-finger DNA-binding transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MET4 YNL103W Leucine-zipper transcriptional activator regulation 1 1 1 chromatin immunoprecipitation-chip evidence
XBP1 YIL101C Transcriptional repressor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAP1 YML007W Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 DNA to cDNA expression microarray evidence
CAD1 YDR423C AP-1-like basic leucine zipper (bZIP) transcriptional activator regulation 1 1 1 DNA to cDNA expression microarray evidence
NAB3 YPL190C RNA-binding protein, subunit of Nrd1 complex (Nrd1p-Nab3p-Sen1p) regulation 1 1 1 quantitative reverse transcription polymerase chain reaction evidence
IPI1 YHR085W Component of the Rix1 complex and possibly pre-replicative complexes genetic 1 1 1 Positive Genetic
BMH1 YER177W 14-3-3 protein, major isoform genetic 1 1 1 Synthetic Growth Defect
CSL4 YNL232W Exosome non-catalytic core component genetic 1 1 1 Positive Genetic
NUT1 YGL151W Component of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
EMP24 YGL200C Component of the p24 complex physical 1 1 1 PCA
IST1 YNL265C Protein with positive role in the multivesicular body sorting pathway genetic 1 1 1 Synthetic Lethality
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
MRPL20 YKR085C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Synthetic Growth Defect
MRPL25 YGR076C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Synthetic Growth Defect
ITC1 YGL133W Subunit of ATP-dependent Isw2p-Itc1p chromatin remodeling complex genetic 1 1 1 Synthetic Growth Defect
MRPL38 YKL170W Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Synthetic Growth Defect
MKT1 YNL085W Protein similar to nucleases that forms a complex with Pbp1p genetic 1 1 1 Negative Genetic
CDC25 YLR310C Membrane bound guanine nucleotide exchange factor genetic 1 1 1 Negative Genetic
HEK2 YBL032W RNA binding protein involved in asymmetric localization of ASH1 mRNA physical 1 1 1 Affinity Capture-RNA
AIM17 YHL021C Protein of unknown function genetic 1 1 1 Negative Genetic
HYP2 YEL034W Translation elongation factor eIF-5A genetic 1 1 1 Positive Genetic
FET3 YMR058W Ferro-O2-oxidoreductase genetic 1 1 1 Synthetic Lethality
CIK1 YMR198W Kinesin-associated protein genetic 1 1 1 Negative Genetic
AVT2 YEL064C Putative transporter genetic 1 1 1 Synthetic Growth Defect
ESS1 YJR017C Peptidylprolyl-cis/trans-isomerase (PPIase) physical 1 1 1 Protein-peptide
ATP20 YPR020W Subunit g of the mitochondrial F1F0 ATP synthase physical 1 1 1 PCA
CWC24 YLR323C General splicing factor genetic 1 1 1 Positive Genetic
LEU4 YNL104C Alpha-isopropylmalate synthase (2-isopropylmalate synthase) genetic 1 1 1 Negative Genetic
NDL1 YLR254C Homolog of nuclear distribution factor NudE genetic 1 1 1 Negative Genetic
IPL1 YPL209C Aurora kinase of chromosomal passenger complex genetic 1 1 1 Negative Genetic
ELO3 YLR372W Elongase physical 1 1 1 PCA
MRF1 YGL143C Mitochondrial translation release factor genetic 1 1 1 Synthetic Lethality
ATP10 YLR393W Assembly factor for the F0 sector of mitochondrial F1F0 ATP synthase genetic 1 1 1 Negative Genetic
COX17 YLL009C Copper metallochaperone that transfers copper to Sco1p and Cox11p genetic 1 1 1 Negative Genetic
DBP6 YNR038W Essential protein involved in ribosome biogenesis genetic 1 1 1 Positive Genetic
MHP1 YJL042W Microtubule-associated protein involved in microtubule organization genetic 1 1 1 Negative Genetic
ARR3 YPR201W Plasma membrane metalloid/H+ antiporter genetic 1 1 1 Synthetic Growth Defect
GEF1 YJR040W Voltage-gated chloride channel genetic 1 1 1 Synthetic Lethality
BOL3 YAL046C Protein involved in Fe-S cluster transfer to mitochondrial clients genetic 1 1 1 Negative Genetic
IFA38 YBR159W Microsomal beta-keto-reductase physical 1 1 1 PCA
MRPL11 YDL202W Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Synthetic Growth Defect
FRE3 YOR381W Ferric reductase genetic 1 1 1 Negative Genetic
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 1 1 1 Negative Genetic
KXD1 YGL079W Subunit of the BLOC-1 complex involved in endosomal maturation genetic 1 1 1 Negative Genetic
MTG1 YMR097C Putative GTPase peripheral to the mitochondrial inner membrane genetic 1 1 1 Negative Genetic
GCD14 YJL125C Subunit of tRNA (1-methyladenosine) methyltransferase genetic 1 1 1 Negative Genetic
CBS1 YDL069C Mitochondrial translational activator of the COB mRNA genetic 1 1 1 Positive Genetic
MRPL40 YPL173W Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Synthetic Growth Defect
MSF1 YPR047W Mitochondrial phenylalanyl-tRNA synthetase genetic 1 1 1 Synthetic Growth Defect
OCA5 YHL029C Cytoplasmic protein required for replication of Brome mosaic virus genetic 1 1 1 Negative Genetic
NEJ1 YLR265C DNA end-binding protein required for nonhomologous end joining (NHEJ) genetic 1 1 1 Negative Genetic
CTA1 YDR256C Catalase A genetic 1 1 1 Phenotypic Enhancement
HXT4 YHR092C High-affinity glucose transporter physical 1 1 1 PCA
HSP32 YPL280W Possible chaperone and cysteine protease genetic 1 1 1 Negative Genetic
EDC1 YGL222C RNA-binding protein that activates mRNA decapping directly genetic 1 1 1 Negative Genetic
EMI1 YDR512C Non-essential protein of unknown function genetic 1 1 1 Synthetic Growth Defect
MRM2 YGL136C Mitochondrial 2' O-ribose methyltransferase genetic 1 1 1 Synthetic Growth Defect
CMC2 YBL059C-A Protein involved in respiratory chain complex assembly or maintenance genetic 1 1 1 Positive Genetic
LIP2 YLR239C Lipoyl ligase genetic 1 1 1 Synthetic Lethality
SND3 YBR106W Involved in SRP-independent protein targeting to the ER physical 1 1 1 PCA
SET2 YJL168C Histone methyltransferase with a role in transcriptional elongation physical 1 1 1 Protein-peptide
SSY1 YDR160W Component of the SPS plasma membrane amino acid sensor system genetic 1 1 1 Negative Genetic
RIP1 YEL024W Ubiquinol-cytochrome-c reductase genetic 1 1 1 Negative Genetic
TOR1 YJR066W PIK-related protein kinase and rapamycin target genetic 1 1 1 Synthetic Growth Defect
TAF1 YGR274C TFIID subunit, involved in RNA pol II transcription initiation genetic 1 1 1 Synthetic Lethality
RPS0A YGR214W Ribosomal 40S subunit protein S0A genetic 1 1 1 Synthetic Growth Defect
STB5 YHR178W Transcription factor genetic 1 1 1 Synthetic Growth Defect
SYS1 YJL004C Integral membrane protein of the Golgi genetic 1 1 1 Synthetic Growth Defect
POR1 YNL055C Mitochondrial porin (voltage-dependent anion channel) genetic 1 1 1 Synthetic Growth Defect
RIM20 YOR275C Protein involved in proteolytic activation of Rim101p genetic 1 1 1 Synthetic Growth Defect
RPS12 YOR369C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Synthetic Growth Defect
SIT1 YEL065W Ferrioxamine B transporter genetic 1 1 1 Synthetic Lethality
ZUO1 YGR285C Ribosome-associated chaperone genetic 1 1 1 Synthetic Lethality
RPL34B YIL052C Ribosomal 60S subunit protein L34B genetic 1 1 1 Synthetic Lethality
RPL39 YJL189W Ribosomal 60S subunit protein L39 genetic 1 1 1 Synthetic Lethality
SWI6 YLR182W Transcription cofactor genetic 1 1 1 Synthetic Lethality
VPS4 YPR173C AAA-ATPase involved in multivesicular body (MVB) protein sorting genetic 1 1 1 Synthetic Lethality
RPP0 YLR340W Conserved ribosomal protein P0 of the ribosomal stalk genetic 1 1 1 Positive Genetic
PBR1 YNL181W Putative oxidoreductase genetic 1 1 1 Positive Genetic
SEH1 YGL100W Subunit of the Nup84 nuclear pore and SEACAT subcomplexes genetic 1 1 1 Positive Genetic
PAC10 YGR078C Part of the heteromeric co-chaperone GimC/prefoldin complex genetic 1 1 1 Positive Genetic
SRM1 YGL097W Nucleotide exchange factor for Gsp1p genetic 1 1 1 Negative Genetic
RPP1 YHR062C Subunit of both RNase MRP and nuclear RNase P genetic 1 1 1 Negative Genetic
RAT1 YOR048C Nuclear 5' to 3' single-stranded RNA exonuclease genetic 1 1 1 Negative Genetic
SGT1 YOR057W Cochaperone protein genetic 1 1 1 Negative Genetic
PRE10 YOR362C Alpha 7 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
RAD53 YPL153C DNA damage response kinase genetic 1 1 1 Negative Genetic
YCR102C YCR102C Putative quinone oxidoreductase genetic 1 1 1 Negative Genetic
TMA64 YDR117C Protein of unknown function that associates with ribosomes genetic 1 1 1 Negative Genetic
ZNF1 YFL052W Zinc cluster transcription factor that regulates respiratory growth genetic 1 1 1 Negative Genetic
SAP4 YGL229C Protein required for function of the Sit4p protein phosphatase genetic 1 1 1 Negative Genetic
SNG1 YGR197C Protein involved in resistance to nitrosoguanidine and 6-azauracil genetic 1 1 1 Negative Genetic
ROF1 YHR177W Putative transcription factor containing a WOPR domain genetic 1 1 1 Negative Genetic
YJL107C YJL107C Putative protein of unknown function genetic 1 1 1 Negative Genetic
YLL006W-A YLL006W-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
TCB3 YML072C Cortical ER protein involved in ER-plasma membrane tethering genetic 1 1 1 Negative Genetic
PHO91 YNR013C Low-affinity vacuolar phosphate transporter genetic 1 1 1 Negative Genetic
SLG1 YOR008C Sensor-transducer of the stress-activated PKC1-MPK1 kinase pathway genetic 1 1 1 Negative Genetic
YOR381W-A YOR381W-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 1 1 1 Negative Genetic
YPC1 YBR183W Alkaline ceramidase genetic 1 1 1 Negative Genetic
ALK2 YBL009W Atypical protein kinase genetic 1 1 1 Negative Genetic
AIM10 YER087W Protein with similarity to tRNA synthetases genetic 1 1 1 Synthetic Lethality
EXO5 YBR163W Mitochondrial 5'-3' exonuclease and sliding exonuclease genetic 1 1 1 Synthetic Growth Defect
HPM1 YIL110W AdoMet-dependent methyltransferase genetic 1 1 1 Synthetic Lethality
MSW1 YDR268W Mitochondrial tryptophanyl-tRNA synthetase genetic 1 1 1 Synthetic Growth Defect