| ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
genetic |
2 |
2 |
2 |
Synthetic Haploinsufficiency, Negative Genetic |
| WHI5 |
YOR083W |
Repressor of G1 transcription |
genetic |
2 |
2 |
2 |
Phenotypic Enhancement, Positive Genetic |
| YPK1 |
YKL126W |
S/T protein kinase |
genetic |
2 |
2 |
2 |
Phenotypic Suppression, Phenotypic Enhancement |
| FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
2 |
1 |
2 |
chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence |
| DBP5 |
YOR046C |
Cytoplasmic ATP-dependent RNA helicase of the DEAD-box family |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| SFP1 |
YLR403W |
Regulates transcription of ribosomal protein and biogenesis genes |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| YAP6 |
YDR259C |
Basic leucine zipper (bZIP) transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| ARC35 |
YNR035C |
Subunit of the ARP2/3 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AIM21 |
YIR003W |
Subunit of a complex that associates with actin filaments |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BGL2 |
YGR282C |
Endo-beta-1,3-glucanase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CAM1 |
YPL048W |
One of two isoforms of the gamma subunit of eEF1B |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BET5 |
YML077W |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BCK1 |
YJL095W |
MAPKKK acting in the protein kinase C signaling pathway |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CBP6 |
YBR120C |
Mitochondrial protein required for translation of the COB mRNA |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| ASR1 |
YPR093C |
Ubiquitin ligase that modifies and regulates RNA Pol II |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATP10 |
YLR393W |
Assembly factor for the F0 sector of mitochondrial F1F0 ATP synthase |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| ACF2 |
YLR144C |
Intracellular beta-1,3-endoglucanase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATP18 |
YML081C-A |
Subunit of the mitochondrial F1F0 ATP synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BTS1 |
YPL069C |
Geranylgeranyl diphosphate synthase (GGPPS) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARR3 |
YPR201W |
Plasma membrane metalloid/H+ antiporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PIR1 |
YKL164C |
O-glycosylated protein required for cell wall stability |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| DPB2 |
YPR175W |
Second largest subunit of DNA polymerase II (DNA polymerase epsilon) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MPT5 |
YGL178W |
mRNA-binding protein of the PUF family |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| VTS1 |
YOR359W |
Flap-structured DNA-binding and RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| GIM4 |
YEL003W |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| IRA2 |
YOL081W |
GTPase-activating protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TIM18 |
YOR297C |
Component of the mitochondrial TIM22 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YME1 |
YPR024W |
Catalytic subunit of i-AAA protease complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CMR1 |
YDL156W |
Nuclear protein with role in transcription, protein quality control |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GEM1 |
YAL048C |
Outer mitochondrial membrane GTPase, subunit of the ERMES complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TDA8 |
YAL064C-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PDB1 |
YBR221C |
E1 beta subunit of the pyruvate dehydrogenase (PDH) complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SWE1 |
YJL187C |
Protein kinase that regulates the G2/M transition |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MRPS17 |
YMR188C |
Mitochondrial ribosomal protein of the small subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HDA1 |
YNL021W |
Catalytic subunit of class II HDA1 histone deacetylase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CMK2 |
YOL016C |
Calmodulin-dependent protein kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HMI1 |
YOL095C |
Mitochondrial inner membrane localized ATP-dependent DNA helicase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PET127 |
YOR017W |
Protein with a role in 5'-end processing of mitochondrial RNAs |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CIN5 |
YOR028C |
Basic leucine zipper (bZIP) transcription factor of the yAP-1 family |
genetic |
1 |
1 |
1 |
Positive Genetic |
| EXO1 |
YOR033C |
5'-3' exonuclease and flap-endonuclease |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HIR2 |
YOR038C |
Subunit of HIR nucleosome assembly complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| OPT2 |
YPR194C |
Oligopeptide transporter |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SEC17 |
YBL050W |
Alpha-SNAP cochaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC27 |
YBL084C |
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| POP7 |
YBR167C |
Subunit of RNase MRP, nuclear RNase P and telomerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MED8 |
YBR193C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TCP1 |
YDR212W |
Alpha subunit of chaperonin-containing T-complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SNU56 |
YDR240C |
Component of U1 snRNP required for mRNA splicing via spliceosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SRP101 |
YDR292C |
Signal recognition particle (SRP) receptor alpha subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TFB1 |
YDR311W |
Subunit of TFIIH and nucleotide excision repair factor 3 complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RSP5 |
YER125W |
NEDD4 family E3 ubiquitin ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CCA1 |
YER168C |
ATP (CTP):tRNA-specific tRNA nucleotidyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YPT1 |
YFL038C |
Rab family GTPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| STT3 |
YGL022W |
Catalytic subunit of the oligosaccharyltransferase complex of the ER l |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MES1 |
YGR264C |
Methionyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PAN1 |
YIR006C |
Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SSL1 |
YLR005W |
Subunit of the core form of RNA polymerase transcription factor TFIIH |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YHC1 |
YLR298C |
Component of the U1 snRNP complex required for pre-mRNA splicing |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LST8 |
YNL006W |
Protein required for the transport of Gap1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TOA1 |
YOR194C |
TFIIA large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SUA7 |
YPR086W |
Transcription factor TFIIB |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ERP2 |
YAL007C |
Member of the p24 family involved in ER to Golgi transport |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FUN19 |
YAL034C |
Non-essential protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GDH3 |
YAL062W |
NADP(+)-dependent glutamate dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| URA7 |
YBL039C |
Major CTP synthase isozyme (see also URA8) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YBR053C |
YBR053C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YBR062C |
YBR062C |
Protein of unknown function that interacts with Msb2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YBR090C |
YBR090C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ICS2 |
YBR157C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EBS1 |
YDR206W |
Protein involved in translation inhibition and nonsense-mediated decay |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PMP3 |
YDR276C |
Small plasma membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MGP12 |
YDR286C |
Mitochondrial protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DFM1 |
YDR411C |
Endoplasmic reticulum (ER) localized protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SGF73 |
YGL066W |
Subunit of DUBm module of SAGA and SLIK |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MAL12 |
YGR292W |
Maltase (alpha-D-glucosidase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL8A |
YHL033C |
Ribosomal 60S subunit protein L8A |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YHR112C |
YHR112C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| JEM1 |
YJL073W |
DnaJ-like chaperone required for nuclear membrane fusion during mating |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PTK2 |
YJR059W |
Serine/threonine protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YJR098C |
YJR098C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NNR2 |
YKL151C |
Widely-conserved NADHX dehydratase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SAC1 |
YKL212W |
Phosphatidylinositol phosphate phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DID2 |
YKR035W-A |
Class E protein of the vacuolar protein-sorting (Vps) pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SHB17 |
YKR043C |
Sedoheptulose bisphosphatase involved in riboneogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRS4 |
YKR052C |
Iron transporter of the mitochondrial carrier family |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PSR1 |
YLL010C |
Plasma membrane-associated protein phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PER33 |
YLR064W |
Protein that localizes to the endoplasmic reticulum |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SRN2 |
YLR119W |
Component of the ESCRT-I complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GUF1 |
YLR289W |
Mitochondrial matrix GTPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBC12 |
YLR306W |
Enzyme that mediates the conjugation of Rub1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VIP1 |
YLR410W |
Bifunctional inositol pyrophosphate kinase and phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TSA1 |
YML028W |
Thioredoxin peroxidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CLU1 |
YMR012W |
Subunit of the eukaryotic translation initiation factor 3 (eIF3) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FPY1 |
YMR178W |
FAD pyrophosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PFK2 |
YMR205C |
Beta subunit of heterooctameric phosphofructokinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SAP30 |
YMR263W |
Component of Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YMR310C |
YMR310C |
Putative methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IZH2 |
YOL002C |
Plasma membrane receptor for plant antifungal osmotin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YOL013W-A |
YOL013W-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RRP6 |
YOR001W |
Nuclear exosome exonuclease component |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SGT2 |
YOR007C |
Glutamine-rich cytoplasmic cochaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YNG1 |
YOR064C |
Subunit of the NuA3 histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EFT1 |
YOR133W |
Elongation factor 2 (EF-2), also encoded by EFT2 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEY1 |
YOR165W |
Dynamin-like GTPase that mediates homotypic ER fusion |
genetic |
1 |
1 |
1 |
Negative Genetic |
| THI72 |
YOR192C |
Transporter of thiamine or related compound |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPR2 |
YOR214C |
Putative spore wall protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MCP1 |
YOR228C |
Mitochondrial protein of unknown function involved in lipid homeostas |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS10A |
YOR293W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HAP5 |
YOR358W |
Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PDE2 |
YOR360C |
High-affinity cyclic AMP phosphodiesterase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YPL071C |
YPL071C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UME1 |
YPL139C |
Component of both the Rpd3S and Rpd3L histone deacetylase complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NEW1 |
YPL226W |
Translation termination and ribosome biogenesis factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| THI21 |
YPL258C |
Hydroxymethylpyrimidine (HMP) and HMP-phosphate kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ROX1 |
YPR065W |
Heme-dependent repressor of hypoxic genes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ILV1 |
YER086W |
Threonine deaminase, catalyzes first step in isoleucine biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MSN2 |
YMR037C |
Stress-responsive transcriptional activator |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| MSN4 |
YKL062W |
Stress-responsive transcriptional activator |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| MSS51 |
YLR203C |
Specific translational activator for the mitochondrial COX1 mRNA |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| APS1 |
YLR170C |
Small subunit of the clathrin-associated adaptor complex AP-1 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BIL1 |
YOR304C-A |
Protein that binds Bud6p and has a role in actin cable assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AIM11 |
YER093C-A |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATG15 |
YCR068W |
Phospholipase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AVL9 |
YLR114C |
Conserved protein involved in exocytic transport from the Golgi |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ATP23 |
YNR020C |
Putative metalloprotease of the mitochondrial inner membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
