Standard name Systematic name Name description Description
HIR2 YOR038C Subunit of HIR nucleosome assembly complex Subunit of HIR nucleosome assembly complex; involved in regulation of histone gene transcription; recruits Swi-Snf complexes to histone gene promoters; promotes heterochromatic gene silencing with Asf1p; relocalizes to the cytosol in response to hypoxia
Visualize the interactome of HIR2
Links to external databases:
SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)
G1(P) 34

CYCLoPs localization & abundance

WT1 WT2 WT3
Mito 0.235 0.426 NaN
Nucleolus 0.147 0.070 NaN
Nucleus 0.787 0.800 0.822
SpindlePole NaN 0.052 0.175
Cytoplasm NaN NaN 0.077

GFP localization & abundance

GFP localization GFP abundance
nucleus 922

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
HIR2 4 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
LSM1 YJL124C Lsm (Like Sm) protein genetic 10 2 7 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SPT2 YER161C Protein involved in negative regulation of transcription genetic 9 2 7 Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
MSI1 YBR195C Subunit of chromatin assembly factor I (CAF-1) genetic 8 2 7 Synthetic Growth Defect, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
CAC2 YML102W Subunit of chromatin assembly factor I (CAF-1), with Rlf2p and Msi1p genetic 8 2 6 Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
RLF2 YPR018W Largest subunit (p90) of the Chromatin Assembly Complex (CAF-1) genetic 8 2 6 Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
PAT1 YCR077C Deadenylation-dependent mRNA-decapping factor genetic 8 2 6 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
HHF1 YBR009C Histone H4 genetic 7 1 5 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
ASF1 YJL115W Nucleosome assembly factor physical 6 3 5 Affinity Capture-Western, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
LSM6 YDR378C Lsm (Like Sm) protein genetic 6 2 5 Negative Genetic, Negative Genetic, Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic
CSE2 YNR010W Subunit of the RNA polymerase II mediator complex genetic 6 1 5 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
MED1 YPR070W Subunit of the RNA polymerase II mediator complex genetic 6 1 5 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
HHT1 YBR010W Histone H3 genetic 6 1 5 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
HIR1 YBL008W Subunit of the HIR complex physical 6 2 4 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western
CDC73 YLR418C Component of the Paf1p complex genetic 5 3 5 Synthetic Lethality, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect
UBP6 YFR010W Ubiquitin-specific protease genetic 5 3 5 Phenotypic Enhancement, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
ARP8 YOR141C Nuclear actin-related protein involved in chromatin remodeling genetic 5 2 5 Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic
LEO1 YOR123C Component of the Paf1 complex genetic 5 2 5 Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
LSM7 YNL147W Lsm (Like Sm) protein genetic 5 2 5 Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Lethality, Negative Genetic
IES3 YLR052W Subunit of the INO80 chromatin remodeling complex genetic 5 1 5 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SPN1 YPR133C Protein involved in RNA polymerase II transcription genetic 5 2 4 Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic
POB3 YML069W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) genetic 5 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
CDC7 YDL017W S/T kinase and catalytic subunit of DDK (Dbf4-dependent kinase) genetic 5 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
DOA1 YKL213C WD-repeat protein involved in ubiquitin-mediated protein degradation genetic 4 2 4 Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic
IES2 YNL215W Protein that associates with the INO80 chromatin remodeling complex genetic 4 2 4 Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic
HTZ1 YOL012C Histone variant H2AZ genetic 4 2 4 Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic
IES5 YER092W Non-essential INO80 chromatin remodeling complex subunit genetic 4 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
NHP10 YDL002C Non-essential INO80 chromatin remodeling complex subunit genetic 4 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SLX8 YER116C Subunit of Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex genetic 4 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
HPC2 YBR215W Subunit of the HIR complex physical 4 2 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western
PMR1 YGL167C High affinity Ca2+/Mn2+ P-type ATPase genetic 4 2 3 Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
STB5 YHR178W Transcription factor genetic 4 2 3 Positive Genetic, Positive Genetic, Negative Genetic, Positive Genetic
SEM1 YDR363W-A 19S proteasome regulatory particle lid subcomplex component genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
YTA7 YGR270W Chromatin-binding ATPase that regulates histone gene expression genetic 3 2 3 Negative Genetic, Synthetic Growth Defect, Negative Genetic
SSN3 YPL042C Component of the RNA polymerase II mediator complex genetic 3 2 3 Negative Genetic, Synthetic Growth Defect, Negative Genetic
HTA1 YDR225W Histone H2A genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
SSN2 YDR443C Subunit of the RNA polymerase II mediator complex genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
SIN3 YOL004W Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
YPT6 YLR262C Rab family GTPase genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
THP2 YHR167W Subunit of the THO and TREX complexes genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
LSM3 YLR438C-A Lsm (Like Sm) protein genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
IES1 YFL013C Subunit of the INO80 chromatin remodeling complex genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
ATG1 YGL180W Protein serine/threonine kinase genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
ELF1 YKL160W Transcription elongation factor with a conserved zinc finger domain genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
HIR3 YJR140C Subunit of the HIR complex physical 3 2 2 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western
RTT106 YNL206C Histone chaperone physical 3 2 2 Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western
MDM10 YAL010C Subunit of both the ERMES and the SAM complex genetic 3 2 2 Negative Genetic, Negative Genetic, Positive Genetic
DPB3 YBR278W Third-largest subunit of DNA polymerase II (DNA polymerase epsilon) genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
DPB4 YDR121W Subunit of DNA pol epsilon and of ISW2 chromatin accessibility complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
PSF1 YDR013W Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p) genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
NBP2 YDR162C Protein involved in the HOG (high osmolarity glycerol) pathway genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
HUR1 YGL168W Protein with a role in DNA repair genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SCS7 YMR272C Sphingolipid alpha-hydroxylase genetic 3 1 2 Positive Genetic, Positive Genetic, Positive Genetic
VPS27 YNR006W Endosomal protein that forms a complex with Hse1p genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
PDE2 YOR360C High-affinity cyclic AMP phosphodiesterase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
HPA2 YPR193C Tetrameric histone acetyltransferase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
DBF4 YDR052C Regulatory subunit of Cdc7p-Dbf4p kinase complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
DER1 YBR201W ER membrane protein that promotes export of misfolded polypeptides genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit genetic 2 2 2 Synthetic Growth Defect, Dosage Lethality
CDC45 YLR103C DNA replication initiation factor genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
CTF18 YMR078C Subunit of a complex with Ctf8p genetic 2 2 2 Phenotypic Enhancement, Negative Genetic
CTK1 YKL139W Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) genetic 2 2 2 Positive Genetic, Synthetic Growth Defect
GCN3 YKR026C Alpha subunit of translation initiation factor eIF2B genetic 2 2 2 Phenotypic Suppression, Positive Genetic
CLU1 YMR012W Subunit of the eukaryotic translation initiation factor 3 (eIF3) genetic 2 2 2 Phenotypic Suppression, Positive Genetic
CDC37 YDR168W Essential Hsp90p co-chaperone genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
HIR1 YBL008W Subunit of the HIR complex genetic 2 2 2 Synthetic Growth Defect, Positive Genetic
SPT4 YGR063C Spt4p/5p (DSIF) transcription elongation factor complex subunit genetic 2 2 2 Negative Genetic, Synthetic Lethality
MLP1 YKR095W Myosin-like protein associated with the nuclear envelope genetic 2 2 2 Phenotypic Suppression, Positive Genetic
TEF4 YKL081W Gamma subunit of translational elongation factor eEF1B genetic 2 2 2 Phenotypic Suppression, Positive Genetic
PUS1 YPL212C tRNA:pseudouridine synthase genetic 2 2 2 Phenotypic Suppression, Positive Genetic
RPA49 YNL248C RNA polymerase I subunit A49 genetic 2 2 2 Negative Genetic, Positive Genetic
MRT4 YKL009W Protein involved in mRNA turnover and ribosome assembly genetic 2 2 2 Positive Genetic, Negative Genetic
SET2 YJL168C Histone methyltransferase with a role in transcriptional elongation genetic 2 2 2 Synthetic Rescue, Negative Genetic
RAD53 YPL153C DNA damage response kinase genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
HHT1 YBR010W Histone H3 physical 2 2 2 Affinity Capture-Western, Affinity Capture-MS
CTK3 YML112W Gamma subunit of C-terminal domain kinase I genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
APC5 YOR249C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 2 2 2 Dosage Rescue, Positive Genetic
DUS3 YLR401C Dihydrouridine synthase genetic 2 2 2 Phenotypic Suppression, Positive Genetic
FKH1 YIL131C Forkhead family transcription factor regulation 2 1 2 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence
ATP11 YNL315C Molecular chaperone genetic 2 1 2 Negative Genetic, Negative Genetic
CKS1 YBR135W Cyclin-dependent protein kinase regulatory subunit and adaptor genetic 2 1 2 Negative Genetic, Negative Genetic
GIS4 YML006C CAAX box containing protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
RPN6 YDL097C Essential, non-ATPase regulatory subunit of the 26S proteasome lid genetic 2 1 2 Negative Genetic, Negative Genetic
SSN8 YNL025C Cyclin-like component of RNA polymerase II holoenzyme genetic 2 1 2 Negative Genetic, Negative Genetic
RSC1 YGR056W Component of the RSC chromatin remodeling complex genetic 2 1 2 Negative Genetic, Negative Genetic
PAC10 YGR078C Part of the heteromeric co-chaperone GimC/prefoldin complex genetic 2 1 2 Negative Genetic, Negative Genetic
MSC1 YML128C Protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
TOP1 YOL006C Topoisomerase I genetic 2 1 2 Negative Genetic, Negative Genetic
SDS3 YIL084C Component of the Rpd3L histone deacetylase complex genetic 2 1 2 Negative Genetic, Negative Genetic
SIC1 YLR079W Cyclin-dependent kinase inhibitor (CKI) genetic 2 1 2 Negative Genetic, Negative Genetic
THP1 YOL072W Nuclear pore-associated protein genetic 2 1 2 Negative Genetic, Negative Genetic
RRP6 YOR001W Nuclear exosome exonuclease component genetic 2 1 2 Negative Genetic, Negative Genetic
PUF4 YGL014W Member of the PUF protein family genetic 2 1 2 Negative Genetic, Negative Genetic
SHP1 YBL058W UBX domain-containing substrate adaptor for Cdc48p genetic 2 1 2 Negative Genetic, Negative Genetic
SUS1 YBR111W-A Global transcriptional regulator, component of SAGA, TREX-2 complexes genetic 2 1 2 Negative Genetic, Negative Genetic
VMA8 YEL051W Subunit D of the V1 peripheral membrane domain of V-ATPase genetic 2 1 2 Negative Genetic, Negative Genetic
YPT31 YER031C Rab family GTPase genetic 2 1 2 Negative Genetic, Negative Genetic
RSM7 YJR113C Mitochondrial ribosomal protein of the small subunit genetic 2 1 2 Negative Genetic, Negative Genetic
TRM9 YML014W tRNA methyltransferase genetic 2 1 2 Negative Genetic, Negative Genetic
IRA2 YOL081W GTPase-activating protein genetic 2 1 2 Negative Genetic, Negative Genetic
PPH22 YDL188C Catalytic subunit of protein phosphatase 2A, PP2A genetic 2 1 2 Negative Genetic, Negative Genetic
SLX5 YDL013W Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex genetic 2 1 2 Negative Genetic, Negative Genetic
VMS1 YDR049W Peptidyl-tRNA hydrolase that releases stalled peptides from ribosomes, genetic 2 1 2 Negative Genetic, Negative Genetic
KKQ8 YKL168C Putative serine/threonine protein kinase with unknown cellular role genetic 2 1 2 Negative Genetic, Negative Genetic
NCS2 YNL119W Protein required for uridine thiolation of Lys(UUU) and Glu(UUC) tRNAs genetic 2 1 2 Negative Genetic, Negative Genetic
VTS1 YOR359W Flap-structured DNA-binding and RNA-binding protein genetic 2 1 2 Negative Genetic, Negative Genetic
VMA13 YPR036W Subunit H of the V1 peripheral membrane domain of V-ATPase genetic 2 1 2 Negative Genetic, Negative Genetic
RPN4 YDL020C Transcription factor that stimulates expression of proteasome genes genetic 2 1 2 Negative Genetic, Negative Genetic
OKP1 YGR179C Outer kinetochore protein required for accurate chromosome segregation genetic 2 1 2 Negative Genetic, Negative Genetic
ORC4 YPR162C Subunit of the origin recognition complex (ORC) genetic 2 1 2 Negative Genetic, Negative Genetic
VPS24 YKL041W One of four subunits of the ESCRT-III complex genetic 2 1 2 Negative Genetic, Negative Genetic
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p genetic 2 1 2 Negative Genetic, Negative Genetic
IRC25 YLR021W Component of a heterodimeric Poc4p-Irc25p chaperone genetic 2 1 2 Negative Genetic, Negative Genetic
FKH2 YNL068C Forkhead family transcription factor genetic 2 1 2 Negative Genetic, Negative Genetic
FUS3 YBL016W Mitogen-activated serine/threonine protein kinase involved in mating genetic 2 1 2 Positive Genetic, Positive Genetic
DUO1 YGL061C Essential subunit of the Dam1 complex (aka DASH complex) genetic 2 1 2 Negative Genetic, Negative Genetic
DID4 YKL002W Class E Vps protein of the ESCRT-III complex genetic 2 1 2 Negative Genetic, Negative Genetic
CLB5 YPR120C B-type cyclin involved in DNA replication during S phase genetic 2 1 2 Negative Genetic, Negative Genetic
HHT2 YNL031C Histone H3 genetic 2 1 2 Negative Genetic, Negative Genetic
DPC25 YPL107W Putative mitochondrial protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
AIM33 YML087C Protein of unknown function, highly conserved across species genetic 2 1 2 Negative Genetic, Negative Genetic
SGV1 YPR161C Cyclin (Bur2p)-dependent protein kinase genetic 2 2 1 Positive Genetic, Negative Genetic
CSE4 YKL049C Centromeric histone H3-like protein genetic 2 2 1 Dosage Lethality, Negative Genetic
ESA1 YOR244W Catalytic subunit of the histone acetyltransferase complex (NuA4) genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 2 1 1 Negative Genetic, Negative Genetic
SSA1 YAL005C ATPase involved in protein folding and NLS-directed nuclear transport physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
SSB1 YDL229W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
SPE1 YKL184W Ornithine decarboxylase genetic 2 1 1 Positive Genetic, Positive Genetic
RPN11 YFR004W Metalloprotease subunit of 19S regulatory particle genetic 2 1 1 Negative Genetic, Negative Genetic
DIA2 YOR080W Origin-binding F-box protein genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
CLB2 YPR119W B-type cyclin involved in cell cycle progression physical 2 1 1 Affinity Capture-Western, Affinity Capture-Western
BAP2 YBR068C High-affinity leucine permease genetic 2 1 1 Positive Genetic, Positive Genetic
FKH2 YNL068C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAP6 YDR259C Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CAD1 YDR423C AP-1-like basic leucine zipper (bZIP) transcriptional activator regulation 1 1 1 DNA to cDNA expression microarray evidence
CMK2 YOL016C Calmodulin-dependent protein kinase regulation 1 1 1 DNA to cDNA expression microarray evidence
YGP1 YNL160W Cell wall-related secretory glycoprotein regulation 1 1 1 DNA to cDNA expression microarray evidence
GIP1 YBR045C Meiosis-specific regulatory subunit of the Glc7p protein phosphatase regulation 1 1 1 DNA to cDNA expression microarray evidence
GPG1 YGL121C Proposed gamma subunit of the heterotrimeric G protein regulation 1 1 1 quantitative reverse transcription polymerase chain reaction evidence
NCA3 YJL116C Protein involved in mitochondrion organization regulation 1 1 1 quantitative reverse transcription polymerase chain reaction evidence
AIM17 YHL021C Protein of unknown function regulation 1 1 1 DNA to cDNA expression microarray evidence
NOG2 YNR053C Putative GTPase regulation 1 1 1 DNA to cDNA expression microarray evidence
YOR385W YOR385W Putative protein of unknown function regulation 1 1 1 DNA to cDNA expression microarray evidence
GAC1 YOR178C Regulatory subunit for Glc7p type-1 protein phosphatase (PP1) regulation 1 1 1 quantitative reverse transcription polymerase chain reaction evidence
XBP1 YIL101C Transcriptional repressor regulation 1 1 1 quantitative reverse transcription polymerase chain reaction evidence
CHD1 YER164W Chromatin remodeler that regulates various aspects of transcription genetic 1 1 1 Synthetic Rescue
CTR9 YOL145C Component of the Paf1p complex involved in transcription elongation genetic 1 1 1 Negative Genetic
CLF1 YLR117C Member of the NineTeen Complex (NTC) genetic 1 1 1 Positive Genetic
DSN1 YIR010W Essential component of the outer kinetochore MIND complex physical 1 1 1 Affinity Capture-MS
GWT1 YJL091C Protein involved in the inositol acylation of GlcN-PI genetic 1 1 1 Positive Genetic
ARP4 YJL081C Nuclear actin-related protein involved in chromatin remodeling genetic 1 1 1 Negative Genetic
EAF1 YDR359C Component of the NuA4 histone acetyltransferase complex genetic 1 1 1 Synthetic Growth Defect
GCD6 YDR211W Catalytic epsilon subunit of the translation initiation factor eIF2B genetic 1 1 1 Negative Genetic
ADH1 YOL086C Alcohol dehydrogenase genetic 1 1 1 Negative Genetic
AXL2 YIL140W Integral plasma membrane protein genetic 1 1 1 Negative Genetic
BRR2 YER172C RNA-dependent ATPase RNA helicase (DEIH box) genetic 1 1 1 Negative Genetic
HAP5 YOR358W Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex genetic 1 1 1 Negative Genetic
GUS1 YGL245W Glutamyl-tRNA synthetase (GluRS) genetic 1 1 1 Positive Genetic
BMH1 YER177W 14-3-3 protein, major isoform genetic 1 1 1 Positive Genetic
DBP3 YGL078C RNA-Dependent ATPase, member of DExD/H-box family genetic 1 1 1 Positive Genetic
CSL4 YNL232W Exosome non-catalytic core component genetic 1 1 1 Negative Genetic
DST1 YGL043W General transcription elongation factor TFIIS genetic 1 1 1 Negative Genetic
GIR2 YDR152W Highly-acidic RWD domain-containing cytoplasmic protein genetic 1 1 1 Positive Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex genetic 1 1 1 Synthetic Growth Defect
APC1 YNL172W Largest subunit of the Anaphase-Promoting Complex/Cyclosome genetic 1 1 1 Positive Genetic
ARO1 YDR127W Pentafunctional arom protein genetic 1 1 1 Negative Genetic
ARP3 YJR065C Essential component of the Arp2/3 complex genetic 1 1 1 Positive Genetic
BDF1 YLR399C BET family transcriptional regulator genetic 1 1 1 Synthetic Lethality
CLP1 YOR250C Component of the cleavage and polyadenylation factor I (CF I) genetic 1 1 1 Negative Genetic
DNA2 YHR164C ATP-dependent 5'-flap endonuclease and DNA helicase genetic 1 1 1 Negative Genetic
ERV25 YML012W Member of the p24 family involved in ER to Golgi transport genetic 1 1 1 Negative Genetic
HHF1 YBR009C Histone H4 physical 1 1 1 Affinity Capture-Western
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
HDA3 YPR179C Subunit of HDA1 histone deacetylase complex genetic 1 1 1 Negative Genetic
GIM3 YNL153C Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Negative Genetic
DAM1 YGR113W Essential subunit of the Dam1 complex (aka DASH complex) genetic 1 1 1 Positive Genetic
DEP1 YAL013W Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
HFI1 YPL254W Adaptor protein required for structural integrity of the SAGA complex genetic 1 1 1 Negative Genetic
BUR2 YLR226W Cyclin for the Sgv1p (Bur1p) protein kinase genetic 1 1 1 Synthetic Lethality
CRN1 YLR429W Coronin genetic 1 1 1 Negative Genetic
EFB1 YAL003W Translation elongation factor 1 beta genetic 1 1 1 Negative Genetic
BDH2 YAL061W Putative medium-chain alcohol dehydrogenase with similarity to BDH1 genetic 1 1 1 Negative Genetic
DTD1 YDL219W D-Tyr-tRNA(Tyr) deacylase genetic 1 1 1 Positive Genetic
FAA4 YMR246W Long chain fatty acyl-CoA synthetase genetic 1 1 1 Positive Genetic
GET2 YER083C Subunit of the GET complex genetic 1 1 1 Negative Genetic
CDC20 YGL116W Activator of anaphase-promoting complex/cyclosome (APC/C) genetic 1 1 1 Negative Genetic
FAR10 YLR238W Protein involved in recovery from arrest in response to pheromone genetic 1 1 1 Negative Genetic
DNL4 YOR005C DNA ligase required for nonhomologous end-joining (NHEJ) genetic 1 1 1 Negative Genetic
HTA1 YDR225W Histone H2A physical 1 1 1 Affinity Capture-MS
TAF4 YMR005W TFIID subunit (48 kDa) physical 1 1 1 Affinity Capture-MS
SNF2 YOR290C Catalytic subunit of the SWI/SNF chromatin remodeling complex physical 1 1 1 Affinity Capture-Western
SNF5 YBR289W Subunit of the SWI/SNF chromatin remodeling complex physical 1 1 1 Affinity Capture-Western
SWI3 YJL176C Subunit of the SWI/SNF chromatin remodeling complex physical 1 1 1 Affinity Capture-Western
MOT1 YPL082C Essential protein involved in regulation of transcription physical 1 1 1 Affinity Capture-Western
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
RFA1 YAR007C Subunit of heterotrimeric Replication Protein A (RPA) physical 1 1 1 Affinity Capture-MS
SPT10 YJL127C Histone H3 acetylase with a role in transcriptional regulation physical 1 1 1 Affinity Capture-MS
SPT10 YJL127C Histone H3 acetylase with a role in transcriptional regulation genetic 1 1 1 Synthetic Lethality
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
MPT5 YGL178W mRNA-binding protein of the PUF family physical 1 1 1 Affinity Capture-RNA
RGP1 YDR137W Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) genetic 1 1 1 Negative Genetic
TAF13 YML098W TFIID subunit (19 kDa) genetic 1 1 1 Negative Genetic
POL30 YBR088C Proliferating cell nuclear antigen (PCNA) genetic 1 1 1 Negative Genetic
MED2 YDL005C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
MSL1 YIR009W U2B component of U2 snRNP genetic 1 1 1 Negative Genetic
VPH2 YKL119C Integral membrane protein required for V-ATPase function genetic 1 1 1 Phenotypic Suppression
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes genetic 1 1 1 Negative Genetic
YBL036C YBL036C Putative non-specific single-domain racemase genetic 1 1 1 Phenotypic Suppression
RAI1 YGL246C Nuclear decapping endonuclease genetic 1 1 1 Negative Genetic
RIC1 YLR039C Protein involved in retrograde transport to the cis-Golgi network genetic 1 1 1 Negative Genetic
SRB8 YCR081W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
NUP84 YDL116W Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
RSC8 YFR037C Component of the RSC chromatin remodeling complex genetic 1 1 1 Negative Genetic
SPT3 YDR392W Subunit of the SAGA and SAGA-like transcriptional regulatory complexes genetic 1 1 1 Negative Genetic
SEC22 YLR268W R-SNARE protein genetic 1 1 1 Negative Genetic
VPS64 YDR200C Protein required for cytoplasm to vacuole targeting of proteins genetic 1 1 1 Negative Genetic
SAP30 YMR263W Component of Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
PFD1 YJL179W Subunit of heterohexameric prefoldin genetic 1 1 1 Positive Genetic
RPO26 YPR187W RNA polymerase subunit ABC23 genetic 1 1 1 Positive Genetic
MON1 YGL124C Subunit of a heterodimeric guanine nucleotide exchange factor (GEF) genetic 1 1 1 Positive Genetic
SPT16 YGL207W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) genetic 1 1 1 Synthetic Growth Defect
UBP3 YER151C Ubiquitin-specific protease that cleaves Ub-protein fusions genetic 1 1 1 Synthetic Growth Defect
TLG2 YOL018C Syntaxin-like t-SNARE genetic 1 1 1 Synthetic Growth Defect
HSP82 YPL240C Hsp90 chaperone genetic 1 1 1 Synthetic Growth Defect
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family genetic 1 1 1 Synthetic Growth Defect
TAD2 YJL035C Subunit of tRNA-specific adenosine-34 deaminase genetic 1 1 1 Negative Genetic
TSR3 YOR006C Protein required for 20S pre-rRNA processing genetic 1 1 1 Negative Genetic
SNT309 YPR101W Member of the NineTeen Complex (NTC) genetic 1 1 1 Negative Genetic
NMD4 YLR363C Protein that may be involved in nonsense-mediated mRNA decay genetic 1 1 1 Positive Genetic
TRM7 YBR061C 2'-O-ribose methyltransferase genetic 1 1 1 Positive Genetic
TAN1 YGL232W Putative tRNA acetyltransferase genetic 1 1 1 Positive Genetic
MSM1 YGR171C Mitochondrial methionyl-tRNA synthetase (MetRS) genetic 1 1 1 Positive Genetic
TRM1 YDR120C tRNA methyltransferase genetic 1 1 1 Positive Genetic
NCL1 YBL024W S-adenosyl-L-methionine-dependent tRNA: m5C-methyltransferase genetic 1 1 1 Positive Genetic
SYF2 YGR129W Member of the NineTeen Complex (NTC) genetic 1 1 1 Positive Genetic
REX4 YOL080C Putative RNA exonuclease genetic 1 1 1 Positive Genetic
MOD5 YOR274W Delta 2-isopentenyl pyrophosphate:tRNA isopentenyl transferase genetic 1 1 1 Positive Genetic
SMM1 YNR015W Dihydrouridine synthase genetic 1 1 1 Positive Genetic
SOL1 YNR034W Protein with a possible role in tRNA export genetic 1 1 1 Positive Genetic
RNY1 YPL123C Vacuolar RNase of the T(2) family genetic 1 1 1 Positive Genetic
TEF1 YPR080W Translational elongation factor EF-1 alpha genetic 1 1 1 Positive Genetic
NAM8 YHR086W RNA binding protein, component of the U1 snRNP protein genetic 1 1 1 Positive Genetic
LSM12 YHR121W Protein of unknown function that may function in RNA processing genetic 1 1 1 Positive Genetic
MOT2 YER068W Ubiquitin-protein ligase subunit of the CCR4-NOT complex genetic 1 1 1 Positive Genetic
RNA14 YMR061W Component of the cleavage and polyadenylation factor I (CF I) genetic 1 1 1 Positive Genetic
MSF1 YPR047W Mitochondrial phenylalanyl-tRNA synthetase genetic 1 1 1 Positive Genetic
VMA9 YCL005W-A Vacuolar H+ ATPase subunit e of the V-ATPase V0 subcomplex genetic 1 1 1 Negative Genetic
LSM4 YER112W Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
TAF8 YML114C TFIID subunit (65 kDa) genetic 1 1 1 Negative Genetic
URE2 YNL229C Nitrogen catabolite repression transcriptional regulator genetic 1 1 1 Negative Genetic
SWC5 YBR231C Component of the SWR1 complex genetic 1 1 1 Positive Genetic
KCC4 YCL024W Protein kinase of the bud neck involved in the septin checkpoint genetic 1 1 1 Negative Genetic
YDL241W YDL241W Putative protein of unknown function genetic 1 1 1 Negative Genetic
RPP1A YDL081C Ribosomal stalk protein P1 alpha genetic 1 1 1 Negative Genetic
MCH1 YDL054C Protein with similarity to mammalian monocarboxylate permeases genetic 1 1 1 Negative Genetic
TDA11 YHR159W Putative protein of unknown function genetic 1 1 1 Negative Genetic
MSB4 YOL112W GTPase-activating protein of the Ras superfamily genetic 1 1 1 Negative Genetic
TGS1 YPL157W Trimethyl guanosine synthase, conserved nucleolar methyl transferase genetic 1 1 1 Negative Genetic
SRO7 YPR032W Effector of Rab GTPase Sec4p genetic 1 1 1 Negative Genetic
PEP5 YMR231W Histone E3 ligase, component of CORVET membrane tethering complex genetic 1 1 1 Synthetic Growth Defect
PEP7 YDR323C Adaptor protein involved in vesicle-mediated vacuolar protein sorting genetic 1 1 1 Synthetic Growth Defect
POP2 YNR052C Subunit of Ccr4-Not complex that mediates 3' to 5' mRNA deadenylation genetic 1 1 1 Synthetic Growth Defect
RAS2 YNL098C GTP-binding protein genetic 1 1 1 Synthetic Growth Defect
NPL3 YDR432W RNA-binding protein genetic 1 1 1 Synthetic Growth Defect
IES6 YEL044W Component of the INO80 chromatin remodeling complex genetic 1 1 1 Synthetic Lethality
MFT1 YML062C Subunit of the THO complex genetic 1 1 1 Negative Genetic
SOH1 YGL127C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
RXT2 YBR095C Component of the histone deacetylase Rpd3L complex genetic 1 1 1 Negative Genetic
SPT8 YLR055C Subunit of the SAGA transcriptional regulatory complex genetic 1 1 1 Negative Genetic
SWR1 YDR334W Swi2/Snf2-related ATPase genetic 1 1 1 Negative Genetic
SAC3 YDR159W mRNA export factor genetic 1 1 1 Negative Genetic
IES4 YOR189W Component of the INO80 chromatiin remodeling complex genetic 1 1 1 Negative Genetic
KIN3 YAR018C Nonessential serine/threonine protein kinase genetic 1 1 1 Positive Genetic
PHO80 YOL001W Cyclin genetic 1 1 1 Negative Genetic
SNT2 YGL131C Subunit of Snt2C complex, RING finger ubiquitin ligase (E3) genetic 1 1 1 Negative Genetic
RSC2 YLR357W Component of the RSC chromatin remodeling complex genetic 1 1 1 Negative Genetic
RAD17 YOR368W Checkpoint protein genetic 1 1 1 Positive Genetic
RTG1 YOL067C Transcription factor (bHLH) involved in interorganelle communication genetic 1 1 1 Positive Genetic
SAT4 YCR008W Ser/Thr protein kinase involved in salt tolerance, nutrient response genetic 1 1 1 Negative Genetic
RCO1 YMR075W Essential component of the Rpd3S histone deacetylase complex genetic 1 1 1 Synthetic Rescue
HOG1 YLR113W Mitogen-activated protein kinase involved in osmoregulation genetic 1 1 1 Phenotypic Suppression
TAF1 YGR274C TFIID subunit, involved in RNA pol II transcription initiation genetic 1 1 1 Synthetic Lethality
KSP1 YHR082C Serine/threonine protein kinase genetic 1 1 1 Negative Genetic
PSY2 YNL201C Subunit of protein phosphatase PP4 complex genetic 1 1 1 Negative Genetic
POL2 YNL262W Catalytic subunit of DNA polymerase (II) epsilon genetic 1 1 1 Synthetic Growth Defect
NSE4 YDL105W Component of the SMC5-SMC6 complex genetic 1 1 1 Positive Genetic
LCB2 YDR062W Component of serine palmitoyltransferase genetic 1 1 1 Positive Genetic
WBP1 YEL002C Beta subunit of the oligosaccharyl transferase glycoprotein complex genetic 1 1 1 Positive Genetic
MCM3 YEL032W Protein involved in DNA replication genetic 1 1 1 Positive Genetic
YKT6 YKL196C Vesicle membrane protein (v-SNARE) with acyltransferase activity genetic 1 1 1 Positive Genetic
MED11 YMR112C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Positive Genetic
NAR1 YNL240C Subunit of the cytosolic iron-sulfur (FeS) protein assembly machinery genetic 1 1 1 Positive Genetic
NSE5 YML023C Component of the SMC5-SMC6 complex genetic 1 1 1 Positive Genetic
OST4 YDL232W Subunit of the oligosaccharyltransferase complex of the ER lumen genetic 1 1 1 Positive Genetic
TFB5 YDR079C-A Component of RNA polymerase II general transcription factor TFIIH genetic 1 1 1 Positive Genetic
SHE9 YDR393W Protein required for normal mitochondrial morphology genetic 1 1 1 Positive Genetic
VPS52 YDR484W Component of the GARP (Golgi-associated retrograde protein) complex genetic 1 1 1 Positive Genetic
MIN10 YFR032C-B Mitochondrial protein of unknown function genetic 1 1 1 Positive Genetic
SEH1 YGL100W Subunit of the Nup84 nuclear pore and SEACAT subcomplexes genetic 1 1 1 Positive Genetic
SEC28 YIL076W Epsilon-COP subunit of the coatomer genetic 1 1 1 Positive Genetic
RPL40B YKR094C Ubiquitin-ribosomal 60S subunit protein L40B fusion protein genetic 1 1 1 Positive Genetic
SLA2 YNL243W Adaptor protein that links actin to clathrin and endocytosis genetic 1 1 1 Positive Genetic
RVS161 YCR009C Amphiphysin-like lipid raft protein genetic 1 1 1 Positive Genetic
RIM20 YOR275C Protein involved in proteolytic activation of Rim101p genetic 1 1 1 Positive Genetic
SCM3 YDL139C Nonhistone component of centromeric chromatin genetic 1 1 1 Negative Genetic
UTP4 YDR324C Subunit of U3-containing 90S preribosome and SSU processome complexes genetic 1 1 1 Negative Genetic
NCB2 YDR397C Subunit of a heterodimeric NC2 transcription regulator complex genetic 1 1 1 Negative Genetic
MMS21 YEL019C Highly conserved SUMO E3 ligase subunit of SMC5-SMC6 complex genetic 1 1 1 Negative Genetic
SCL1 YGL011C Alpha 1 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
RPS2 YGL123W Protein component of the small (40S) subunit genetic 1 1 1 Negative Genetic
PTI1 YGR156W Essential component of CPF (cleavage and polyadenylation factor) genetic 1 1 1 Negative Genetic
RPN1 YHR027C Non-ATPase base subunit of the 19S RP of the 26S proteasome genetic 1 1 1 Negative Genetic
RPP1 YHR062C Subunit of both RNase MRP and nuclear RNase P genetic 1 1 1 Negative Genetic
NOP9 YJL010C Essential subunit of U3-containing 90S preribosome genetic 1 1 1 Negative Genetic
NUP82 YJL061W Linker nucleoporin component of the nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
PSF2 YJL072C Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p) genetic 1 1 1 Negative Genetic
MPE1 YKL059C Subunit of CPF cleavage and polyadenylation factor and E3 Ub-ligase genetic 1 1 1 Negative Genetic
RPL17A YKL180W Ribosomal 60S subunit protein L17A genetic 1 1 1 Negative Genetic
LAS1 YKR063C Endonuclease involved in pre-rRNA processing at both ends of ITS2 genetic 1 1 1 Negative Genetic
SMD2 YLR275W Core Sm protein Sm D2 genetic 1 1 1 Negative Genetic
PRP39 YML046W U1 snRNP protein involved in splicing genetic 1 1 1 Negative Genetic
RAP1 YNL216W Essential DNA-binding transcription regulator that binds many loci genetic 1 1 1 Negative Genetic
RPN7 YPR108W Essential non-ATPase regulatory subunit of the 26S proteasome genetic 1 1 1 Negative Genetic
MED8 YBR193C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
TAF5 YBR198C Subunit (90 kDa) of TFIID and SAGA complexes genetic 1 1 1 Negative Genetic
TSC13 YDL015C Enoyl reductase genetic 1 1 1 Negative Genetic
TRS23 YDR246W Core component of transport protein particle (TRAPP) complexes I-III genetic 1 1 1 Negative Genetic
RPB7 YDR404C RNA polymerase II subunit B16 genetic 1 1 1 Negative Genetic
RPN12 YFR052W Subunit of the 19S regulatory particle of the 26S proteasome lid genetic 1 1 1 Negative Genetic
RNA15 YGL044C Component of the cleavage and polyadenylation factor I (CF I) genetic 1 1 1 Negative Genetic
RPT6 YGL048C ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Negative Genetic
SLD3 YGL113W Protein involved in the initiation of DNA replication genetic 1 1 1 Negative Genetic
SNU114 YKL173W GTPase component of U5 snRNP involved in mRNA splicing via spliceosome genetic 1 1 1 Negative Genetic
RPF2 YKR081C Essential protein involved in rRNA maturation and ribosomal assembly genetic 1 1 1 Negative Genetic
SEC65 YML105C Subunit of the signal recognition particle (SRP) genetic 1 1 1 Negative Genetic
SPC24 YMR117C Component of the kinetochore-associated Ndc80 complex genetic 1 1 1 Negative Genetic
RRP5 YMR229C RNA binding protein involved in synthesis of 18S and 5.8S rRNAs genetic 1 1 1 Negative Genetic
NOP2 YNL061W rRNA m5C methyltransferase genetic 1 1 1 Negative Genetic
RPC34 YNR003C RNA polymerase III subunit C34 genetic 1 1 1 Negative Genetic
TOA1 YOR194C TFIIA large subunit genetic 1 1 1 Negative Genetic
PRE10 YOR362C Alpha 7 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
NAB3 YPL190C RNA-binding protein, subunit of Nrd1 complex (Nrd1p-Nab3p-Sen1p) genetic 1 1 1 Negative Genetic
PRE2 YPR103W Beta 5 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
SWH1 YAR042W Protein similar to mammalian oxysterol-binding protein genetic 1 1 1 Negative Genetic
PIN4 YBL051C Protein involved in G2/M phase progression and response to DNA damage genetic 1 1 1 Negative Genetic
SCO1 YBR037C Copper-binding protein of mitochondrial inner membrane genetic 1 1 1 Negative Genetic
UMP1 YBR173C Chaperone required for correct maturation of the 20S proteasome genetic 1 1 1 Negative Genetic
RPL4B YDR012W Ribosomal 60S subunit protein L4B genetic 1 1 1 Negative Genetic
SPO71 YDR104C Meiosis-specific protein required for prospore membrane morphogenesis genetic 1 1 1 Negative Genetic
TMS1 YDR105C Vacuolar membrane protein of unknown function genetic 1 1 1 Negative Genetic
KGD2 YDR148C Dihydrolipoyl transsuccinylase genetic 1 1 1 Negative Genetic
MSS116 YDR194C Mitochondrial transcription elongation factor genetic 1 1 1 Negative Genetic
SSD1 YDR293C Translational repressor genetic 1 1 1 Negative Genetic
IPK1 YDR315C Inositol 1,3,4,5,6-pentakisphosphate 2-kinase genetic 1 1 1 Negative Genetic
MRPL35 YDR322W Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
ZRG8 YER033C Protein of unknown function genetic 1 1 1 Negative Genetic
PET117 YER058W Assembly factor that couples heme a synthesis to complex IV assembly genetic 1 1 1 Negative Genetic
ICP55 YER078C Mitochondrial aminopeptidase genetic 1 1 1 Negative Genetic
PET122 YER153C Mitochondrial translational activator specific for the COX3 mRNA genetic 1 1 1 Negative Genetic
OXA1 YER154W Mitochondrial inner membrane insertase genetic 1 1 1 Negative Genetic
RPO41 YFL036W Mitochondrial RNA polymerase genetic 1 1 1 Negative Genetic
RMD9 YGL107C Mitochondrial protein that controls mitochondrial gene expression genetic 1 1 1 Negative Genetic
YGL114W YGL114W Putative protein of unknown function genetic 1 1 1 Negative Genetic
YGL235W YGL235W Putative protein of unknown function genetic 1 1 1 Negative Genetic
RTG2 YGL252C Sensor of mitochondrial dysfunction genetic 1 1 1 Negative Genetic
QCR9 YGR183C Subunit 9 of ubiquinol cytochrome-c reductase (Complex III) genetic 1 1 1 Negative Genetic
LNP1 YHR192W Lunapark family member involved in ER network formation genetic 1 1 1 Negative Genetic
XBP1 YIL101C Transcriptional repressor genetic 1 1 1 Negative Genetic
MGA2 YIR033W ER membrane protein involved in regulation of OLE1 transcription genetic 1 1 1 Negative Genetic
MEF2 YJL102W Mitochondrial elongation factor involved in translational elongation genetic 1 1 1 Negative Genetic
QCR8 YJL166W Subunit 8 of ubiquinol cytochrome-c reductase (Complex III) genetic 1 1 1 Negative Genetic
NUC1 YJL208C Major mitochondrial nuclease genetic 1 1 1 Negative Genetic
SMY1 YKL079W Kinesin-like myosin passenger-protein genetic 1 1 1 Negative Genetic
YLR415C YLR415C Putative protein of unknown function genetic 1 1 1 Negative Genetic
YPT7 YML001W Rab family GTPase genetic 1 1 1 Negative Genetic
YML018C YML018C Protein of unknown function genetic 1 1 1 Negative Genetic
RCF1 YML030W Cytochrome c oxidase subunit genetic 1 1 1 Negative Genetic
YML053C YML053C Putative protein of unknown function genetic 1 1 1 Negative Genetic
PEX9 YMR018W Peroxisomal membrane signal receptor for peroxisomal matrix proteins genetic 1 1 1 Negative Genetic
MSS1 YMR023C Mitochondrial protein genetic 1 1 1 Negative Genetic
POR1 YNL055C Mitochondrial porin (voltage-dependent anion channel) genetic 1 1 1 Negative Genetic
MRPL17 YNL252C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
MRPL10 YNL284C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
RIM21 YNL294C pH sensor molecule, component of the RIM101 pathway genetic 1 1 1 Negative Genetic
RIM1 YCR028C-A ssDNA-binding protein essential for mitochondrial genome maintenance genetic 1 1 1 Negative Genetic
MKC7 YDR144C GPI-anchored aspartyl protease genetic 1 1 1 Negative Genetic
MAG1 YER142C 3-methyl-adenine DNA glycosylase genetic 1 1 1 Negative Genetic
HSV2 YGR223C Phosphatidylinositol 3,5-bisphosphate-binding protein genetic 1 1 1 Negative Genetic
SNF6 YHL025W Subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Negative Genetic
UBI4 YLL039C Ubiquitin genetic 1 1 1 Negative Genetic
PBA1 YLR199C Protein involved in 20S proteasome assembly genetic 1 1 1 Negative Genetic
PMA2 YPL036W Plasma membrane H+-ATPase genetic 1 1 1 Negative Genetic
LEE1 YPL054W Zinc-finger protein of unknown function genetic 1 1 1 Negative Genetic
SPR1 YOR190W Sporulation-specific exo-1,3-beta-glucanase genetic 1 1 1 Negative Genetic
MET7 YOR241W Folylpolyglutamate synthetase genetic 1 1 1 Negative Genetic
RAX1 YOR301W Protein involved in establishing bud site selection genetic 1 1 1 Negative Genetic
RPL20B YOR312C Ribosomal 60S subunit protein L20B genetic 1 1 1 Negative Genetic
MNE1 YOR350C Protein involved in splicing Group I aI5-beta intron from COX1 mRNA genetic 1 1 1 Negative Genetic
TAF14 YPL129W Subunit of TFIID, TFIIF, INO80, SWI/SNF, and NuA3 complexes genetic 1 1 1 Negative Genetic
HOB2 YPR117W Protein with structural similarity to lipid transport protein Vps13p genetic 1 1 1 Negative Genetic
YNG2 YHR090C Subunit of NuA4, an essential histone acetyltransferase complex genetic 1 1 1 Negative Genetic
PPH21 YDL134C Catalytic subunit of protein phosphatase 2A, PP2A genetic 1 1 1 Positive Genetic
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 1 1 1 Negative Genetic
RAD52 YML032C Protein involved in homologous recombination genetic 1 1 1 Negative Genetic
RPL11A YPR102C Ribosomal 60S subunit protein L11A genetic 1 1 1 Negative Genetic
RPS19B YNL302C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
PMA1 YGL008C Plasma membrane P2-type H+-ATPase genetic 1 1 1 Negative Genetic
SNT1 YCR033W Set3C histone deacetylase scaffold genetic 1 1 1 Positive Genetic
PDC2 YDR081C Transcription factor for thiamine-regulated genes genetic 1 1 1 Positive Genetic
NUT1 YGL151W Component of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
ORC3 YLL004W Subunit of the origin recognition complex (ORC) genetic 1 1 1 Negative Genetic
RPL37A YLR185W Ribosomal 60S subunit protein L37A genetic 1 1 1 Positive Genetic
SKY1 YMR216C SR protein kinase (SRPK) genetic 1 1 1 Negative Genetic
RRD2 YPL152W Peptidyl-prolyl cis/trans-isomerase genetic 1 1 1 Negative Genetic
KAR3 YPR141C Minus-end-directed microtubule motor genetic 1 1 1 Positive Genetic
IML3 YBR107C Outer kinetochore protein and component of the Ctf19 complex genetic 1 1 1 Negative Genetic
PTC1 YDL006W Type 2C protein phosphatase (PP2C) genetic 1 1 1 Negative Genetic
PAD1 YDR538W Phenylacrylic acid decarboxylase genetic 1 1 1 Negative Genetic
SIS2 YKR072C Negative regulatory subunit of protein phosphatase 1 (Ppz1p) genetic 1 1 1 Negative Genetic
SRV2 YNL138W CAP (cyclase-associated protein) genetic 1 1 1 Negative Genetic
ILV1 YER086W Threonine deaminase, catalyzes first step in isoleucine biosynthesis genetic 1 1 1 Negative Genetic
TUB4 YLR212C Gamma-tubulin genetic 1 1 1 Synthetic Rescue
FAA1 YOR317W Long chain fatty acyl-CoA synthetase genetic 1 1 1 Negative Genetic
DPB11 YJL090C DNA replication initiation protein genetic 1 1 1 Negative Genetic
HAP3 YBL021C Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex genetic 1 1 1 Negative Genetic
DBF2 YGR092W Ser/Thr kinase involved in transcription and stress response genetic 1 1 1 Positive Genetic
GCR2 YNL199C Transcriptional activator of genes involved in glycolysis genetic 1 1 1 Positive Genetic
DCK1 YLR422W Dock family protein (Dedicator Of CytoKinesis), homolog of human DOCK1 genetic 1 1 1 Positive Genetic
CDD1 YLR245C Cytidine deaminase genetic 1 1 1 Positive Genetic
GTR1 YML121W Subunit of a TORC1-stimulating GTPase and the EGO/GSE complex genetic 1 1 1 Negative Genetic
CAK1 YFL029C Cyclin-dependent kinase-activating kinase genetic 1 1 1 Negative Genetic
GPI16 YHR188C Subunit of the glycosylphosphatidylinositol transamidase complex genetic 1 1 1 Negative Genetic
AIM4 YBR194W Protein proposed to be associated with the nuclear pore complex genetic 1 1 1 Positive Genetic
BOS1 YLR078C v-SNARE (vesicle specific SNAP receptor) genetic 1 1 1 Negative Genetic
CEP3 YMR168C Essential kinetochore protein genetic 1 1 1 Negative Genetic
CSE4 YKL049C Centromeric histone H3-like protein physical 1 1 1 Affinity Capture-Western
BUR6 YER159C Subunit of a heterodimeric NC2 transcription regulator complex genetic 1 1 1 Negative Genetic
ALF1 YNL148C Alpha-tubulin folding protein genetic 1 1 1 Synthetic Growth Defect
BRN1 YBL097W Subunit of the condensin complex genetic 1 1 1 Positive Genetic
BUB1 YGR188C Protein kinase involved in the cell cycle checkpoint into anaphase genetic 1 1 1 Negative Genetic
CLC1 YGR167W Clathrin light chain genetic 1 1 1 Negative Genetic
CTF8 YHR191C Subunit of a complex with Ctf18p genetic 1 1 1 Negative Genetic
CTK2 YJL006C Beta subunit of C-terminal domain kinase I (CTDK-I) genetic 1 1 1 Synthetic Growth Defect
ELO2 YCR034W Fatty acid elongase, involved in sphingolipid biosynthesis genetic 1 1 1 Negative Genetic
CSG2 YBR036C Endoplasmic reticulum membrane protein genetic 1 1 1 Negative Genetic
ABF1 YKL112W DNA binding protein with possible chromatin-reorganizing activity genetic 1 1 1 Positive Genetic
ARG82 YDR173C Inositol polyphosphate multikinase (IPMK) genetic 1 1 1 Negative Genetic
ERV29 YGR284C Protein localized to COPII-coated vesicles genetic 1 1 1 Negative Genetic
EAF7 YNL136W Subunit of the NuA4 histone acetyltransferase complex genetic 1 1 1 Negative Genetic
BTS1 YPL069C Geranylgeranyl diphosphate synthase (GGPPS) genetic 1 1 1 Positive Genetic
DCC1 YCL016C Subunit of a complex with Ctf8p and Ctf18p genetic 1 1 1 Positive Genetic
GRX4 YER174C Glutathione-dependent oxidoreductase and glutathione S-transferase genetic 1 1 1 Negative Genetic
CBS1 YDL069C Mitochondrial translational activator of the COB mRNA genetic 1 1 1 Positive Genetic
GIS2 YNL255C Translational activator for mRNAs with internal ribosome entry sites genetic 1 1 1 Positive Genetic
COA3 YJL062W-A Mitochondrial protein required for cytochrome c oxidase assembly genetic 1 1 1 Negative Genetic
ALT1 YLR089C Alanine transaminase (glutamic pyruvic transaminase) genetic 1 1 1 Negative Genetic
DOS2 YDR068W Protein of unknown function genetic 1 1 1 Negative Genetic
GPI12 YMR281W ER membrane protein involved in the second step of GPI anchor assembly genetic 1 1 1 Negative Genetic
EOS1 YNL080C Protein involved in N-glycosylation genetic 1 1 1 Negative Genetic
COX10 YPL172C Heme A:farnesyltransferase genetic 1 1 1 Negative Genetic
GPI19 YDR437W Subunit of GPI-GlcNAc transferase involved in synthesis of GlcNAc-PI genetic 1 1 1 Negative Genetic
CDC50 YCR094W Endosomal protein that interacts with phospholipid flippase Drs2p genetic 1 1 1 Negative Genetic
CGR1 YGL029W Protein involved in nucleolar integrity and processing of pre-rRNA genetic 1 1 1 Positive Genetic
GPI13 YLL031C ER membrane localized phosphoryltransferase genetic 1 1 1 Positive Genetic
EDC1 YGL222C RNA-binding protein that activates mRNA decapping directly genetic 1 1 1 Positive Genetic
EMI1 YDR512C Non-essential protein of unknown function genetic 1 1 1 Negative Genetic
COX9 YDL067C Subunit VIIa of cytochrome c oxidase (Complex IV) genetic 1 1 1 Negative Genetic
CDC1 YDR182W Putative mannose-ethanolamine phosphate phosphodiesterase genetic 1 1 1 Negative Genetic
CPR8 YNR028W Peptidyl-prolyl cis-trans isomerase (cyclophilin) genetic 1 1 1 Negative Genetic
DFR1 YOR236W Dihydrofolate reductase involved in tetrahydrofolate biosynthesis genetic 1 1 1 Negative Genetic