| SPC34 |
YKR037C |
Essential subunit of the Dam1 complex (aka DASH complex) |
physical |
15 |
5 |
11 |
Two-hybrid, Two-hybrid, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Two-hybrid, Affinity Capture-MS, Co-purification, Two-hybrid, Two-hybrid, Co-purification, Co-purification, Two-hybrid, Two-hybrid, Reconstituted Complex |
| DAD1 |
YDR016C |
Essential subunit of the Dam1 complex (aka DASH complex) |
physical |
14 |
5 |
11 |
Two-hybrid, Two-hybrid, Two-hybrid, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Two-hybrid, Affinity Capture-MS, Two-hybrid, Two-hybrid, Co-purification, Two-hybrid |
| DAM1 |
YGR113W |
Essential subunit of the Dam1 complex (aka DASH complex) |
physical |
13 |
3 |
9 |
Two-hybrid, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Two-hybrid, Two-hybrid, Affinity Capture-Western, Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid |
| DAD2 |
YKR083C |
Essential subunit of the Dam1 complex (aka DASH complex) |
physical |
4 |
3 |
4 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Two-hybrid |
| ASK1 |
YKL052C |
Essential subunit of the Dam1 complex (aka DASH complex) |
physical |
4 |
3 |
4 |
Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Co-purification |
| DSN1 |
YIR010W |
Essential component of the outer kinetochore MIND complex |
physical |
4 |
2 |
4 |
Affinity Capture-MS, Co-crystal Structure, Affinity Capture-MS, Affinity Capture-MS |
| RIC1 |
YLR039C |
Protein involved in retrograde transport to the cis-Golgi network |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| MAD2 |
YJL030W |
Component of the spindle-assembly checkpoint complex |
genetic |
3 |
2 |
3 |
Synthetic Growth Defect, Negative Genetic, Negative Genetic |
| BCK1 |
YJL095W |
MAPKKK acting in the protein kinase C signaling pathway |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| YPT6 |
YLR262C |
Rab family GTPase |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| BIM1 |
YER016W |
Microtubule plus end-tracking protein |
physical |
3 |
1 |
3 |
Two-hybrid, Two-hybrid, Two-hybrid |
| DAD1 |
YDR016C |
Essential subunit of the Dam1 complex (aka DASH complex) |
genetic |
3 |
2 |
2 |
Synthetic Lethality, Negative Genetic, Negative Genetic |
| PSE1 |
YMR308C |
Karyopherin/importin that interacts with the nuclear pore complex |
physical |
3 |
2 |
2 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western |
| PDE2 |
YOR360C |
High-affinity cyclic AMP phosphodiesterase |
genetic |
3 |
2 |
2 |
Dosage Rescue, Negative Genetic, Negative Genetic |
| BUB3 |
YOR026W |
Kinetochore checkpoint WD40 repeat protein |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| SEM1 |
YDR363W-A |
19S proteasome regulatory particle lid subcomplex component |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| MAD3 |
YJL013C |
Subunit of spindle-assembly checkpoint complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| VPS27 |
YNR006W |
Endosomal protein that forms a complex with Hse1p |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| OST3 |
YOR085W |
Gamma subunit of the oligosaccharyltransferase complex of the ER lumen |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| IPL1 |
YPL209C |
Aurora kinase of chromosomal passenger complex |
genetic |
2 |
2 |
2 |
Synthetic Rescue, Positive Genetic |
| HSK3 |
YKL138C-A |
Essential subunit of the Dam1 complex (aka DASH complex) |
physical |
2 |
2 |
2 |
Co-purification, Two-hybrid |
| SPC19 |
YDR201W |
Essential subunit of the Dam1 complex (aka DASH complex) |
physical |
2 |
2 |
2 |
Affinity Capture-MS, Two-hybrid |
| GLC7 |
YER133W |
Type 1 S/T protein phosphatase (PP1) catalytic subunit |
genetic |
2 |
2 |
2 |
Dosage Lethality, Negative Genetic |
| ASK1 |
YKL052C |
Essential subunit of the Dam1 complex (aka DASH complex) |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Negative Genetic |
| DAD4 |
YDR320C-A |
Essential subunit of the Dam1 complex (aka DASH complex) |
physical |
2 |
2 |
2 |
Affinity Capture-MS, Two-hybrid |
| CDC73 |
YLR418C |
Component of the Paf1p complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| BUD31 |
YCR063W |
Component of the SF3b subcomplex of the U2 snRNP |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| BUB2 |
YMR055C |
Mitotic exit network regulator |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| BFA1 |
YJR053W |
Subunit of a two-component GTPase-activating protein, Bfa1p-Bub2p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| BEM3 |
YPL115C |
Rho GTPase activating protein (RhoGAP) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| DIA2 |
YOR080W |
Origin-binding F-box protein |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| CLB2 |
YPR119W |
B-type cyclin involved in cell cycle progression |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SHE1 |
YBL031W |
Mitotic spindle protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| LTE1 |
YAL024C |
Protein similar to GDP/GTP exchange factors |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PMT2 |
YAL023C |
Protein O-mannosyltransferase of the ER membrane |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SWC3 |
YAL011W |
Protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| VPS8 |
YAL002W |
Membrane-binding component of the CORVET complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| NUP60 |
YAR002W |
FG-nucleoporin component of central core of the nuclear pore complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| HMT1 |
YBR034C |
Nuclear SAM-dependent mono- and asymmetric methyltransferase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SWC5 |
YBR231C |
Component of the SWR1 complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| GBP2 |
YCL011C |
Poly(A+) RNA-binding protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PER1 |
YCR044C |
Protein of the endoplasmic reticulum |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| THR4 |
YCR053W |
Threonine synthase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PAT1 |
YCR077C |
Deadenylation-dependent mRNA-decapping factor |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| PPH21 |
YDL134C |
Catalytic subunit of protein phosphatase 2A, PP2A |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| VAM6 |
YDL077C |
Guanine nucleotide exchange factor for the GTPase Gtr1p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| NHP10 |
YDL002C |
Non-essential INO80 chromatin remodeling complex subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| VPS41 |
YDR080W |
Subunit of the HOPS endocytic tethering complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| NUM1 |
YDR150W |
Protein required for nuclear migration |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| NBP2 |
YDR162C |
Protein involved in the HOG (high osmolarity glycerol) pathway |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RTT103 |
YDR289C |
Protein involved in transcription termination by RNA polymerase II |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SWR1 |
YDR334W |
Swi2/Snf2-related ATPase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| VPS74 |
YDR372C |
Golgi PI4K effector, PtdIns4P sensor, and retention receptor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PPM1 |
YDR435C |
Carboxyl methyltransferase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| VPS72 |
YDR485C |
Htz1p-binding component of the SWR1 complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PAC11 |
YDR488C |
Dynein intermediate chain, microtubule motor protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| WWM1 |
YFL010C |
WW domain containing protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SMI1 |
YGR229C |
Protein involved in the regulation of cell wall synthesis |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PPE1 |
YHR075C |
Protein with carboxyl methyl esterase activity |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| STB5 |
YHR178W |
Transcription factor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SDS3 |
YIL084C |
Component of the Rpd3L histone deacetylase complex |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| YJL206C |
YJL206C |
Putative protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SET2 |
YJL168C |
Histone methyltransferase with a role in transcriptional elongation |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| VPS55 |
YJR044C |
Late endosomal protein involved in late endosome to vacuole transport |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SDH2 |
YLL041C |
Iron-sulfur protein subunit of succinate dehydrogenase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| FKS1 |
YLR342W |
Catalytic subunit of 1,3-beta-D-glucan synthase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| VPS9 |
YML097C |
Guanine nucleotide exchange factor (GEF) and ubiquitin receptor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PPZ1 |
YML016C |
Serine/threonine protein phosphatase Z, isoform of Ppz2p |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| NAM7 |
YMR080C |
ATP-dependent RNA helicase of the SFI superfamily |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| SKY1 |
YMR216C |
SR protein kinase (SRPK) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SAP30 |
YMR263W |
Component of Rpd3L histone deacetylase complex |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| JNM1 |
YMR294W |
Component of the yeast dynactin complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| DYN3 |
YMR299C |
Dynein light intermediate chain (LIC) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| FPR1 |
YNL135C |
Peptidyl-prolyl cis-trans isomerase (PPIase) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| YDJ1 |
YNL064C |
Type I HSP40 co-chaperone |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| VPS68 |
YOL129W |
Vacuolar membrane protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| TLG2 |
YOL018C |
Syntaxin-like t-SNARE |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| HIR2 |
YOR038C |
Subunit of HIR nucleosome assembly complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| VAM3 |
YOR106W |
Syntaxin-like vacuolar t-SNARE |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| LEO1 |
YOR123C |
Component of the Paf1 complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| VPS17 |
YOR132W |
Subunit of the membrane-associated retromer complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SLK19 |
YOR195W |
Kinetochore-associated protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PAC1 |
YOR269W |
Regulator of dynein, involved in intracellular transport |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| VPH1 |
YOR270C |
Subunit a of the vacuolar-ATPase V0 domain |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RRD2 |
YPL152W |
Peptidyl-prolyl cis/trans-isomerase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SUR1 |
YPL057C |
Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| KAR3 |
YPR141C |
Minus-end-directed microtubule motor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| MAD1 |
YGL086W |
Coiled-coil protein involved in spindle-assembly checkpoint |
genetic |
2 |
1 |
2 |
Synthetic Lethality, Synthetic Lethality |
| ERG3 |
YLR056W |
C-5 sterol desaturase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| BRE5 |
YNR051C |
Ubiquitin protease cofactor |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| CLB3 |
YDL155W |
B-type cyclin involved in cell cycle progression |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CYK3 |
YDL117W |
SH3-domain protein located in the bud neck and cytokinetic actin ring |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ALT1 |
YLR089C |
Alanine transaminase (glutamic pyruvic transaminase) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| BST1 |
YFL025C |
GPI inositol deacylase of the endoplasmic reticulum (ER) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
genetic |
2 |
2 |
1 |
Positive Genetic, Negative Genetic |
| SBA1 |
YKL117W |
Co-chaperone that binds and regulates Hsp90 family chaperones |
physical |
2 |
2 |
1 |
Reconstituted Complex, Two-hybrid |
| PRE2 |
YPR103W |
Beta 5 subunit of the 20S proteasome |
genetic |
2 |
2 |
1 |
Positive Genetic, Negative Genetic |
| AME1 |
YBR211C |
Essential kinetochore protein associated with microtubules and SPBs |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| CDC37 |
YDR168W |
Essential Hsp90p co-chaperone |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SPC19 |
YDR201W |
Essential subunit of the Dam1 complex (aka DASH complex) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| STU2 |
YLR045C |
Microtubule polymerase of the XMAP215/Dis1 family |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| PDS1 |
YDR113C |
Securin |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| GPI16 |
YHR188C |
Subunit of the glycosylphosphatidylinositol transamidase complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SPC24 |
YMR117C |
Component of the kinetochore-associated Ndc80 complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| PRE6 |
YOL038W |
Alpha 4 subunit of the 20S proteasome |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SGV1 |
YPR161C |
Cyclin (Bur2p)-dependent protein kinase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| VPS5 |
YOR069W |
Nexin-1 homolog |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SFP1 |
YLR403W |
Regulates transcription of ribosomal protein and biogenesis genes |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| IXR1 |
YKL032C |
Transcriptional repressor that regulates hypoxic genes during normoxia |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| TFC7 |
YOR110W |
RNA pol III transcription initiation factor complex (TFIIIC) subunit |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| CKA1 |
YIL035C |
Alpha catalytic subunit of casein kinase 2 (CK2) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CKB2 |
YOR039W |
Beta' regulatory subunit of casein kinase 2 (CK2) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARP4 |
YJL081C |
Nuclear actin-related protein involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BRE1 |
YDL074C |
E3 ubiquitin ligase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ARL1 |
YBR164C |
Soluble GTPase with a role in regulation of membrane traffic |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AIR2 |
YDL175C |
RNA-binding subunit of the TRAMP nuclear RNA surveillance complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CDC48 |
YDL126C |
AAA ATPase with protein-unfoldase activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARP7 |
YPR034W |
Component of both the SWI/SNF and RSC chromatin remodeling complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ALA1 |
YOR335C |
Cytoplasmic and mitochondrial alanyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| CDC39 |
YCR093W |
Subunit of the CCR4-NOT1 core complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ACC1 |
YNR016C |
Acetyl-CoA carboxylase, biotin containing enzyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BEM1 |
YBR200W |
Protein containing SH3-domains |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC14 |
YFR028C |
Protein phosphatase required for mitotic exit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC11 |
YJR076C |
Component of the septin ring that is required for cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC12 |
YHR107C |
Component of the septin ring that is required for cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CKS1 |
YBR135W |
Cyclin-dependent protein kinase regulatory subunit and adaptor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CLP1 |
YOR250C |
Component of the cleavage and polyadenylation factor I (CF I) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COP1 |
YDL145C |
Alpha subunit of COPI vesicle coatomer complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CTK1 |
YKL139W |
Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CYR1 |
YJL005W |
Adenylate cyclase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| DCP1 |
YOL149W |
Subunit of the Dcp1p-Dcp2p decapping enzyme complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| DNA2 |
YHR164C |
ATP-dependent 5'-flap endonuclease and DNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CIA2 |
YHR122W |
Component of cytosolic iron-sulfur protein assembly (CIA) machinery |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CDC23 |
YHR166C |
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| CRM1 |
YGR218W |
Nuclear export factor, exportin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CSE2 |
YNR010W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| COG3 |
YER157W |
Essential component of the conserved oligomeric Golgi complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CMD1 |
YBR109C |
Calmodulin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CWC22 |
YGR278W |
Spliceosome-associated protein that is required for pre-mRNA splicing |
genetic |
1 |
1 |
1 |
Positive Genetic |
| DAM1 |
YGR113W |
Essential subunit of the Dam1 complex (aka DASH complex) |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| DEP1 |
YAL013W |
Component of the Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| DAL3 |
YIR032C |
Ureidoglycolate lyase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BET5 |
YML077W |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BRO1 |
YPL084W |
Cytoplasmic class E vacuolar protein sorting (VPS) factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DRS2 |
YAL026C |
Trans-golgi network aminophospholipid translocase (flippase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DUN1 |
YDL101C |
Cell-cycle checkpoint S/T protein kinase |
genetic |
1 |
1 |
1 |
Dosage Lethality |
| CAF120 |
YNL278W |
Part of the CCR4-NOT transcriptional regulatory complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CCT5 |
YJR064W |
Subunit of the cytosolic chaperonin Cct ring complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| AXL1 |
YPR122W |
Haploid specific endoprotease of a-factor mating pheromone |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARE2 |
YNR019W |
Acyl-CoA:sterol acyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CTF13 |
YMR094W |
Subunit of the CBF3 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ADD66 |
YKL206C |
Protein involved in 20S proteasome assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CIK1 |
YMR198W |
Kinesin-associated protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AIR1 |
YIL079C |
Zinc knuckle protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AFG3 |
YER017C |
Mitochondrial inner membrane m-AAA protease component |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DAD2 |
YKR083C |
Essential subunit of the Dam1 complex (aka DASH complex) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DUO1 |
YGL061C |
Essential subunit of the Dam1 complex (aka DASH complex) |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| IPL1 |
YPL209C |
Aurora kinase of chromosomal passenger complex |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| MAM33 |
YIL070C |
Acidic protein of the mitochondrial matrix |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MAM33 |
YIL070C |
Acidic protein of the mitochondrial matrix |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NAP1 |
YKR048C |
Histone chaperone and assembly chaperone for Rps6a/b |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PSE1 |
YMR308C |
Karyopherin/importin that interacts with the nuclear pore complex |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| KSS1 |
YGR040W |
Mitogen-activated protein kinase (MAPK) |
physical |
1 |
1 |
1 |
Biochemical Activity |
| SHE1 |
YBL031W |
Mitotic spindle protein |
physical |
1 |
1 |
1 |
Two-hybrid |
| SLI15 |
YBR156C |
Subunit of the conserved chromosomal passenger complex (CPC) |
physical |
1 |
1 |
1 |
Two-hybrid |
| SLI15 |
YBR156C |
Subunit of the conserved chromosomal passenger complex (CPC) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| STU2 |
YLR045C |
Microtubule polymerase of the XMAP215/Dis1 family |
physical |
1 |
1 |
1 |
Two-hybrid |
| SMT3 |
YDR510W |
Ubiquitin-like protein of the SUMO family |
physical |
1 |
1 |
1 |
PCA |
| MPT5 |
YGL178W |
mRNA-binding protein of the PUF family |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| HIR1 |
YBL008W |
Subunit of the HIR complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ETR1 |
YBR026C |
2-enoyl thioester reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SUL1 |
YBR294W |
High affinity sulfate permease of the SulP anion transporter family |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YCR023C |
YCR023C |
Vacuolar membrane protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VMS1 |
YDR049W |
Peptidyl-tRNA hydrolase that releases stalled peptides from ribosomes, |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SSD1 |
YDR293C |
Translational repressor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IES5 |
YER092W |
Non-essential INO80 chromatin remodeling complex subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWI4 |
YER111C |
DNA binding component of the SBF complex (Swi4p-Swi6p) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SLX8 |
YER116C |
Subunit of Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MSH4 |
YFL003C |
Protein involved in meiotic recombination |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ZRT1 |
YGL255W |
High-affinity zinc transporter of the plasma membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RTF1 |
YGL244W |
Subunit of RNAPII-associated chromatin remodeling Paf1 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YGL242C |
YGL242C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KIP3 |
YGL216W |
Kinesin-related antiparallel sliding motor protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VAM7 |
YGL212W |
Vacuolar SNARE protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBA4 |
YHR111W |
E1-like protein that activates Urm1p before urmylation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| POT1 |
YIL160C |
3-ketoacyl-CoA thiolase with broad chain length specificity |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ICE2 |
YIL090W |
Integral ER membrane protein with type-III transmembrane domains |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PIR5 |
YJL160C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LAS21 |
YJL062W |
Mannose-ethanolamine phosphotransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YJR011C |
YJR011C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HOM6 |
YJR139C |
Homoserine dehydrogenase (L-homoserine:NADP oxidoreductase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MCR1 |
YKL150W |
Mitochondrial NADH-cytochrome b5 reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PLN1 |
YKR046C |
Perilipin, involved in formation and stability of lipid droplets |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TRK2 |
YKR050W |
Component of the Trk1p-Trk2p potassium transport system |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DYN1 |
YKR054C |
Cytoplasmic heavy chain dynein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SRL3 |
YKR091W |
Repressor of transcription at Start |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LDB18 |
YLL049W |
Component of the dynactin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBI4 |
YLL039C |
Ubiquitin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VTA1 |
YLR181C |
Multivesicular body (MVB) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LIP2 |
YLR239C |
Lipoyl ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YLR287C |
YLR287C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEI1 |
YLR404W |
Seipin involved in lipid droplet (LD) assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS71 |
YML041C |
Nucleosome-binding component of the SWR1 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YMD8 |
YML038C |
Putative nucleotide sugar transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FET3 |
YMR058W |
Ferro-O2-oxidoreductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SAM37 |
YMR060C |
Component of the Sorting and Assembly Machinery (SAM) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TRM11 |
YOL124C |
Catalytic subunit of adoMet-dependent tRNA methyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MET22 |
YOL064C |
Bisphosphate-3'-nucleotidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PTC5 |
YOR090C |
Mitochondrial type 2C protein phosphatase (PP2C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RGA1 |
YOR127W |
GTPase-activating protein for polarity-regulator Cdc42p (RhoGAP) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LIP5 |
YOR196C |
Protein involved in biosynthesis of the coenzyme lipoic acid |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MCT1 |
YOR221C |
Predicted malonyl-CoA:ACP transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GIM5 |
YML094W |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HOF1 |
YMR032W |
F-BAR protein that regulates actin cytoskeleton organization |
genetic |
1 |
1 |
1 |
Positive Genetic |
| VMA11 |
YPL234C |
Vacuolar ATPase V0 domain subunit c' |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YBP2 |
YGL060W |
Central kinetochore associated protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| TEL2 |
YGR099W |
Subunit of the ASTRA complex, involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KRE29 |
YER038C |
Subunit of the SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PKC1 |
YBL105C |
Protein serine/threonine kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TAF5 |
YBR198C |
Subunit (90 kDa) of TFIID and SAGA complexes |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TSC13 |
YDL015C |
Enoyl reductase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| POL3 |
YDL102W |
Catalytic subunit of DNA polymerase delta |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NSE4 |
YDL105W |
Component of the SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SLU7 |
YDR088C |
RNA splicing factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TAF12 |
YDR145W |
Subunit (61/68 kDa) of TFIID and SAGA complexes |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TCP1 |
YDR212W |
Alpha subunit of chaperonin-containing T-complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RRP45 |
YDR280W |
Exosome non-catalytic core component |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GPI19 |
YDR437W |
Subunit of GPI-GlcNAc transferase involved in synthesis of GlcNAc-PI |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SMC1 |
YFL008W |
Subunit of the multiprotein cohesin complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SAM35 |
YHR083W |
Component of the sorting and assembly machinery (SAM) complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MET30 |
YIL046W |
F-box protein containing five copies of the WD40 motif |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NEO1 |
YIL048W |
Phospholipid translocase (flippase) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MCM10 |
YIL150C |
Essential chromatin-associated protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| URA6 |
YKL024C |
Uridylate kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YJU2 |
YKL095W |
Essential protein required for pre-mRNA splicing |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SNU114 |
YKL173W |
GTPase component of U5 snRNP involved in mRNA splicing via spliceosome |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NOP56 |
YLR197W |
Essential evolutionarily-conserved nucleolar protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| KAP95 |
YLR347C |
Karyopherin beta |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SMC6 |
YLR383W |
Subunit of the SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TAF4 |
YMR005W |
TFIID subunit (48 kDa) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PRP24 |
YMR268C |
Splicing factor that reanneals snRNPs during spliceosome recycling |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HRP1 |
YOL123W |
Subunit of cleavage factor I |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MED7 |
YOL135C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SGT1 |
YOR057W |
Cochaperone protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPB2 |
YOR151C |
RNA polymerase II second largest subunit B150 |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GPN2 |
YOR262W |
Putative GTPase with a specific role in RNA pol II and polIII biogenes |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MOT1 |
YPL082C |
Essential protein involved in regulation of transcription |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NUP116 |
YMR047C |
FG-nucleoporin component of central core of the nuclear pore complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RFC1 |
YOR217W |
Subunit of heteropentameric Replication factor C (RF-C) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SWD1 |
YAR003W |
Subunit of the COMPASS (Set1C) complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| UBC4 |
YBR082C |
Ubiquitin-conjugating enzyme (E2) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RXT2 |
YBR095C |
Component of the histone deacetylase Rpd3L complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SNT1 |
YCR033W |
Set3C histone deacetylase scaffold |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TPS2 |
YDR074W |
Phosphatase subunit of the trehalose-6-P synthase/phosphatase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MSN5 |
YDR335W |
Karyopherin |
genetic |
1 |
1 |
1 |
Positive Genetic |
| LSM6 |
YDR378C |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| IST3 |
YIR005W |
Component of the U2 snRNP |
genetic |
1 |
1 |
1 |
Positive Genetic |
| LSM1 |
YJL124C |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PBS2 |
YJL128C |
MAP kinase kinase of the HOG signaling pathway |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPS21B |
YJL136C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
| OAR1 |
YKL055C |
Mitochondrial 3-oxoacyl-[acyl-carrier-protein] reductase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPS0B |
YLR048W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TMA23 |
YMR269W |
Nucleolar protein implicated in ribosome biogenesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
| EOS1 |
YNL080C |
Protein involved in N-glycosylation |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PHO23 |
YNL097C |
Component of the Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SIN3 |
YOL004W |
Component of both the Rpd3S and Rpd3L histone deacetylase complexes |
genetic |
1 |
1 |
1 |
Positive Genetic |
| IES4 |
YOR189W |
Component of the INO80 chromatiin remodeling complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPS10A |
YOR293W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
| LGE1 |
YPL055C |
Protein involved in histone H2B ubiquitination |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SSE1 |
YPL106C |
ATPase component of heat shock protein Hsp90 chaperone complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| LEA1 |
YPL213W |
Component of U2 snRNP complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MED1 |
YPR070W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| LAA2 |
YBL010C |
Clathrin adaptor (adaptin) accessory protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TDA5 |
YLR426W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TOF1 |
YNL273W |
Subunit of a replication-pausing checkpoint complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RFT1 |
YBL020W |
Membrane protein required for translocation of Man5GlcNac2-PP-Dol |
genetic |
1 |
1 |
1 |
Negative Genetic |
| REB1 |
YBR049C |
RNA polymerase I enhancer binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RIB5 |
YBR256C |
Riboflavin synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NCB2 |
YDR397C |
Subunit of a heterodimeric NC2 transcription regulator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPI17 |
YDR434W |
Transmembrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| WBP1 |
YEL002C |
Beta subunit of the oligosaccharyl transferase glycoprotein complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC18 |
YBR080C |
AAA ATPase and SNARE disassembly chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EXO84 |
YBR102C |
Exocyst subunit with dual roles in exocytosis and spliceosome assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TRS20 |
YBR254C |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPT2 |
YDL007W |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPN6 |
YDL097C |
Essential, non-ATPase regulatory subunit of the 26S proteasome lid |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KIN28 |
YDL108W |
Ser/Thr protein kinase and subunit of TFIIK, a TFIIH subassembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FAL1 |
YDR021W |
Nucleolar protein required for maturation of 18S rRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PCF11 |
YDR228C |
mRNA 3' end processing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC26 |
YDR238C |
Essential beta-coat protein of the COPI coatomer |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPI11 |
YDR302W |
ER membrane protein involved in a late step of GPI anchor assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RSC3 |
YDR303C |
Component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPI8 |
YDR331W |
Catalytic subunit of the ER membrane GPI transamidase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPB7 |
YDR404C |
RNA polymerase II subunit B16 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC20 |
YDR498C |
Membrane glycoprotein v-SNARE |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PUP3 |
YER094C |
Beta 3 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MOB2 |
YFL034C-B |
Activator of Cbk1p kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RSC8 |
YFR037C |
Component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRE4 |
YFR050C |
Beta 7 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPN1 |
YHR027C |
Non-ATPase base subunit of the 19S RP of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KAR2 |
YJL034W |
ATPase involved in protein import into the ER |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GWT1 |
YJL091C |
Protein involved in the inositol acylation of GlcN-PI |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NUP85 |
YJR042W |
Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FIP1 |
YJR093C |
Subunit of cleavage polyadenylation factor (CPF) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPI13 |
YLL031C |
ER membrane localized phosphoryltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SED5 |
YLR026C |
cis-Golgi t-SNARE syntaxin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GAA1 |
YLR088W |
Subunit of the GPI:protein transamidase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC22 |
YLR268W |
R-SNARE protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GAB1 |
YLR459W |
Subunit of the glycosylphosphatidylinositol transamidase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TEM1 |
YML064C |
GTPase involved in initiation of Mitotic Exit Network (MEN) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RNA14 |
YMR061W |
Component of the cleavage and polyadenylation factor I (CF I) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VTI1 |
YMR197C |
Protein involved in cis-Golgi membrane traffic |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RNT1 |
YMR239C |
Nuclear dsRNA-specific ribonuclease (RNase III) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPI15 |
YNL038W |
Protein involved in the synthesis of GlcNAc-PI |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPC98 |
YNL126W |
Component of the microtubule-nucleating Tub4p (gamma-tubulin) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KRE33 |
YNL132W |
Acetyltransferase required for biogenesis of small ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MVD1 |
YNR043W |
Mevalonate pyrophosphate decarboxylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NUF2 |
YOL069W |
Component of the kinetochore-associated Ndc80 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RAT1 |
YOR048C |
Nuclear 5' to 3' single-stranded RNA exonuclease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| OST2 |
YOR103C |
Epsilon subunit of the oligosaccharyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SMP3 |
YOR149C |
Alpha 1,2-mannosyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PUP1 |
YOR157C |
Beta 2 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ESA1 |
YOR244W |
Catalytic subunit of the histone acetyltransferase complex (NuA4) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPT4 |
YOR259C |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRE10 |
YOR362C |
Alpha 7 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ERG10 |
YPL028W |
Acetyl-CoA C-acetyltransferase (acetoacetyl-CoA thiolase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC16 |
YPL085W |
COPII vesicle coat protein required for ER transport vesicle budding |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPN7 |
YPR108W |
Essential non-ATPase regulatory subunit of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPN1 |
YPR133C |
Protein involved in RNA polymerase II transcription |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC11 |
YIR022W |
18kDa catalytic subunit of the Signal Peptidase Complex (SPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RSC4 |
YKR008W |
Component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SOF1 |
YLL011W |
Protein required for biogenesis of 40S (small) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RIA1 |
YNL163C |
Cytoplasmic GTPase/eEF2-like factor involved in ribosomal biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LAS17 |
YOR181W |
Actin assembly factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KIN3 |
YAR018C |
Nonessential serine/threonine protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SLA1 |
YBL007C |
Cytoskeletal protein binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PEP1 |
YBL017C |
Type I transmembrane sorting receptor for multiple vacuolar hydrolases |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MTC4 |
YBR255W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PTC1 |
YDL006W |
Type 2C protein phosphatase (PP2C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| OST4 |
YDL232W |
Subunit of the oligosaccharyltransferase complex of the ER lumen |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWI5 |
YDR146C |
Transcription factor that recruits Mediator and Swi/Snf complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HOM2 |
YDR158W |
Aspartic beta semi-aldehyde dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SAC3 |
YDR159W |
mRNA export factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RAV2 |
YDR202C |
Subunit of RAVE complex (Rav1p, Rav2p, Skp1p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UME6 |
YDR207C |
Rpd3L histone deacetylase complex subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBX5 |
YDR330W |
UBX domain-containing protein that interacts with Cdc48p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RVS167 |
YDR388W |
Calmodulin-binding actin-associated protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS60 |
YDR486C |
Protein involved in late endosome to vacuole transport |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FTR1 |
YER145C |
High affinity iron permease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IES1 |
YFL013C |
Subunit of the INO80 chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NPR3 |
YHL023C |
Subunit of the Iml1p/SEACIT complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GOS1 |
YHL031C |
v-SNARE protein involved in Golgi transport |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS29 |
YHR012W |
Subunit of the membrane-associated retromer complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SLT2 |
YHR030C |
Serine/threonine MAP kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RCI37 |
YIL077C |
Protein that associates with the large mitoribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SYS1 |
YJL004C |
Integral membrane protein of the Golgi |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS53 |
YJL029C |
Component of the GARP (Golgi-associated retrograde protein) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS35 |
YJL154C |
Endosomal subunit of membrane-associated retromer complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SOP4 |
YJL192C |
ER-membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RAV1 |
YJR033C |
Subunit of RAVE complex (Rav1p, Rav2p, Skp1p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FPS1 |
YLL043W |
Aquaglyceroporin, plasma membrane channel |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LAM6 |
YLR072W |
Sterol transporter that transfers sterols between membranes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EMP46 |
YLR080W |
Integral membrane component of ER-derived COPII-coated vesicles |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HCR1 |
YLR192C |
eIF3j component of translation initiation factor 3 (eIF3) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HRD3 |
YLR207W |
ER membrane protein that plays a central role in ERAD |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VRP1 |
YLR337C |
Verprolin, proline-rich actin-associated protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YPT7 |
YML001W |
Rab family GTPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PSP2 |
YML017W |
Asn rich cytoplasmic protein that contains RGG motifs |
genetic |
1 |
1 |
1 |
Negative Genetic |
| URA5 |
YML106W |
Major orotate phosphoribosyltransferase (OPRTase) isozyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBC7 |
YMR022W |
Ubiquitin conjugating enzyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EIS1 |
YMR031C |
Component of the eisosome required for proper eisosome assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PKR1 |
YMR123W |
V-ATPase assembly factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GAS1 |
YMR307W |
Beta-1,3-glucanosyltransferase required for cell wall assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PUB1 |
YNL016W |
Poly (A)+ RNA-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HDA1 |
YNL021W |
Catalytic subunit of class II HDA1 histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PMS1 |
YNL082W |
ATP-binding protein required for mismatch repair |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EAF7 |
YNL136W |
Subunit of the NuA4 histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YNL140C |
YNL140C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ITR2 |
YOL103W |
Myo-inositol transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VAM10 |
YOR068C |
Protein involved in vacuole morphogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SNC2 |
YOR327C |
Vesicle membrane receptor protein (v-SNARE) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MET12 |
YPL023C |
Protein with MTHFR activity in vitro |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LCL1 |
YPL056C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS30 |
YPL120W |
Subunit of phosphatidylinositol (PtdIns) 3-kinase complexes I and II |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NIP100 |
YPL174C |
Large subunit of the dynactin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VIK1 |
YPL253C |
Protein that forms a kinesin-14 heterodimeric motor with Kar3p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NTO1 |
YPR031W |
Subunit of the NuA3 histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ISR1 |
YPR106W |
Predicted protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MAY24 |
YPR153W |
Peripheral ER membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS4 |
YPR173C |
AAA-ATPase involved in multivesicular body (MVB) protein sorting |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KAP104 |
YBR017C |
Transportin or cytosolic karyopherin beta 2 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SUS1 |
YBR111W-A |
Global transcriptional regulator, component of SAGA, TREX-2 complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| STP22 |
YCL008C |
Component of the ESCRT-I complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RGP1 |
YDR137W |
Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL27B |
YDR471W |
Ribosomal 60S subunit protein L27B |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS3 |
YDR495C |
Component of CORVET membrane tethering complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RIP1 |
YEL024W |
Ubiquinol-cytochrome-c reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VMA8 |
YEL051W |
Subunit D of the V1 peripheral membrane domain of V-ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRS1 |
YIR021W |
Splicing protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IMA5 |
YJL216C |
Alpha-glucosidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PML1 |
YLR016C |
Subunit of the RES complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PER33 |
YLR064W |
Protein that localizes to the endoplasmic reticulum |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SRN2 |
YLR119W |
Component of the ESCRT-I complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IKI3 |
YLR384C |
Subunit of Elongator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YML003W |
YML003W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MFT1 |
YML062C |
Subunit of the THO complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS20 |
YMR077C |
Myristoylated subunit of the ESCRT-III complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MIN3 |
YMR182W-A |
Mitochondrial protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPD3 |
YNL330C |
Histone deacetylase, component of both the Rpd3S and Rpd3L complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PET494 |
YNR045W |
Mitochondrial translational activator specific for the COX3 mRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS21 |
YOR089C |
Endosomal Rab family GTPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DID4 |
YKL002W |
Class E Vps protein of the ESCRT-III complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CSM3 |
YMR048W |
Replication fork associated factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CAK1 |
YFL029C |
Cyclin-dependent kinase-activating kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COQ5 |
YML110C |
2-hexaprenyl-6-methoxy-1,4-benzoquinone methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AIM4 |
YBR194W |
Protein proposed to be associated with the nuclear pore complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| APC11 |
YDL008W |
Catalytic core subunit, Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COG6 |
YNL041C |
Component of the conserved oligomeric Golgi complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CET1 |
YPL228W |
RNA 5'-triphosphatase involved in mRNA 5' capping |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARP6 |
YLR085C |
Actin-related protein that binds nucleosomes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BUB1 |
YGR188C |
Protein kinase involved in the cell cycle checkpoint into anaphase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DBF4 |
YDR052C |
Regulatory subunit of Cdc7p-Dbf4p kinase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CSG2 |
YBR036C |
Endoplasmic reticulum membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATP10 |
YLR393W |
Assembly factor for the F0 sector of mitochondrial F1F0 ATP synthase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ARL3 |
YPL051W |
ARF-like small GTPase of the RAS superfamily |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DPM1 |
YPR183W |
Dolichol phosphate mannose (Dol-P-Man) synthase of ER membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CNN1 |
YFR046C |
Kinetochore protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CSF1 |
YLR087C |
Protein with structural similarity to lipid transport protein Vps13p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ALG1 |
YBR110W |
Mannosyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DAD3 |
YBR233W-A |
Essential subunit of the Dam1 complex (aka DASH complex) |
physical |
1 |
1 |
1 |
Two-hybrid |
| COI1 |
YDR381C-A |
Mitochondrial assembly factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COQ10 |
YOL008W |
Coenzyme Q (ubiquinone) binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATG38 |
YLR211C |
Homodimeric subunit of autophagy-specific PtdIns-3-kinase complex I |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATP12 |
YJL180C |
Assembly factor for F1 sector of mitochondrial F1F0 ATP synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BIL1 |
YOR304C-A |
Protein that binds Bud6p and has a role in actin cable assembly |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| COA1 |
YIL157C |
Mitochondrial inner membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ADK2 |
YER170W |
Mitochondrial adenylate kinase |
physical |
1 |
1 |
1 |
PCA |
| DCW1 |
YKL046C |
Putative mannosidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CSI2 |
YOL007C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CRS5 |
YOR031W |
Copper-binding metallothionein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CBP4 |
YGR174C |
Mitochondrial protein required for assembly of cytochrome bc1 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CMC1 |
YKL137W |
Copper-binding protein of the mitochondrial intermembrane space |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC1 |
YDR182W |
Putative mannose-ethanolamine phosphate phosphodiesterase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CHM7 |
YJL049W |
Yeast homolog of human CHMP7, localizes to the endoplasmic reticulum |
genetic |
1 |
1 |
1 |
Negative Genetic |
