Standard name Systematic name Name description Description
KSS1 YGR040W Mitogen-activated protein kinase (MAPK) Mitogen-activated protein kinase (MAPK); involved in signal transduction pathways that control filamentous growth and pheromone response; regulates septum assembly, and may directly phosphorylate Bni4p; the KSS1 gene is nonfunctional in S288C strains and functional in W303 strains
Visualize the interactome of KSS1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Mito 0.234 NaN NaN
Nucleus 0.868 0.812 0.836
Vac/Vac Memb NaN 0.149 0.097
Cytoplasm NaN NaN 0.079

GFP localization & abundance

GFP localization GFP abundance
cytoplasm, nucleus 5480

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
KSS1 3 2 0 2 0

Enzyme information

Catalyzed reactions in Yeast8

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
STE7 YDL159W Signal transducing MAP kinase kinase physical 16 8 13 Affinity Capture-MS, Two-hybrid, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Two-hybrid, Two-hybrid, Protein-peptide, Affinity Capture-Western, Reconstituted Complex, FRET, Biochemical Activity, Affinity Capture-MS, PCA, PCA
DIG1 YPL049C MAP kinase-responsive inhibitor of the Ste12p transcription factor physical 10 5 7 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Two-hybrid, Two-hybrid, Biochemical Activity, Biochemical Activity, Two-hybrid, Affinity Capture-MS
FUS3 YBL016W Mitogen-activated serine/threonine protein kinase involved in mating genetic 9 3 9 Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Suppression, Phenotypic Enhancement, Negative Genetic, Phenotypic Suppression, Phenotypic Suppression
STE12 YHR084W Transcription factor that is activated by a MAPK signaling cascade physical 8 4 8 Affinity Capture-MS, Reconstituted Complex, Reconstituted Complex, Two-hybrid, Reconstituted Complex, Biochemical Activity, Two-hybrid, Affinity Capture-MS
DIG2 YDR480W MAP kinase-responsive inhibitor of the Ste12p transcription factor physical 8 4 7 Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Two-hybrid, Two-hybrid, Biochemical Activity, Two-hybrid, Affinity Capture-MS
HOG1 YLR113W Mitogen-activated protein kinase involved in osmoregulation genetic 5 3 5 Synthetic Rescue, Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Suppression, Phenotypic Suppression
STE11 YLR362W Signal transducing MEK kinase physical 5 4 4 Affinity Capture-MS, Reconstituted Complex, Two-hybrid, Two-hybrid, PCA
FKH1 YIL131C Forkhead family transcription factor regulation 4 3 4 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation- exonuclease evidence, ChEC-Seq experiments
MSG5 YNL053W Dual-specificity protein phosphatase physical 4 3 4 Reconstituted Complex, Reconstituted Complex, PCA, Two-hybrid
BEM3 YPL115C Rho GTPase activating protein (RhoGAP) physical 4 3 3 Affinity Capture-MS, PCA, Two-hybrid, PCA
SST2 YLR452C GTPase-activating protein for Gpa1p genetic 4 2 3 Phenotypic Suppression, Negative Genetic, Negative Genetic, Negative Genetic
THP2 YHR167W Subunit of the THO and TREX complexes genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
DIG1 YPL049C MAP kinase-responsive inhibitor of the Ste12p transcription factor genetic 3 2 3 Phenotypic Enhancement, Negative Genetic, Negative Genetic
TEC1 YBR083W Transcription factor targeting filamentation genes and Ty1 expression physical 3 2 3 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS
STE5 YDR103W Pheromone-responsive MAPK scaffold protein physical 3 2 3 Reconstituted Complex, Reconstituted Complex, Two-hybrid
ANP1 YEL036C Subunit of the alpha-1,6 mannosyltransferase complex genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
SEC61 YLR378C Conserved ER protein translocation channel genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
BCK2 YER167W Serine/threonine-rich protein involved in PKC1 signaling pathway physical 3 2 2 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western
HIR1 YBL008W Subunit of the HIR complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
YCR016W YCR016W Putative protein of unknown function genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
FKH2 YNL068C Forkhead family transcription factor regulation 2 2 2 chromatin immunoprecipitation- exonuclease evidence, ChEC-Seq experiments
GUS1 YGL245W Glutamyl-tRNA synthetase (GluRS) physical 2 2 2 Affinity Capture-MS, Biochemical Activity
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 2 2 2 Synthetic Haploinsufficiency, Negative Genetic
STE11 YLR362W Signal transducing MEK kinase genetic 2 2 2 Phenotypic Enhancement, Phenotypic Suppression
STE7 YDL159W Signal transducing MAP kinase kinase genetic 2 2 2 Phenotypic Enhancement, Phenotypic Suppression
STE12 YHR084W Transcription factor that is activated by a MAPK signaling cascade genetic 2 2 2 Dosage Rescue, Phenotypic Suppression
NAP1 YKR048C Histone chaperone and assembly chaperone for Rps6a/b physical 2 2 2 Affinity Capture-MS, Biochemical Activity
PBS2 YJL128C MAP kinase kinase of the HOG signaling pathway genetic 2 2 2 Synthetic Rescue, Phenotypic Enhancement
BNI4 YNL233W Targeting subunit for Glc7p protein phosphatase physical 2 2 2 PCA, Affinity Capture-Western
TSC11 YER093C Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p) physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RGC1 YPR115W Putative regulator of the Fps1p glycerol channel physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SNF1 YDR477W AMP-activated S/T protein kinase genetic 2 1 2 Negative Genetic, Negative Genetic
PDR1 YGL013C Transcription factor that regulates the pleiotropic drug response genetic 2 1 2 Negative Genetic, Negative Genetic
RCK1 YGL158W Protein kinase involved in oxidative stress response genetic 2 1 2 Negative Genetic, Negative Genetic
RPL17B YJL177W Ribosomal 60S subunit protein L17B genetic 2 1 2 Negative Genetic, Negative Genetic
VPH1 YOR270C Subunit a of the vacuolar-ATPase V0 domain genetic 2 1 2 Negative Genetic, Negative Genetic
TAF8 YML114C TFIID subunit (65 kDa) genetic 2 1 2 Negative Genetic, Negative Genetic
WHI3 YNL197C RNA binding protein that modulates mRNA stability genetic 2 1 2 Negative Genetic, Negative Genetic
KAR4 YCL055W Transcription factor required for response to pheromones genetic 2 1 2 Negative Genetic, Negative Genetic
ERG2 YMR202W C-8 sterol isomerase genetic 2 1 2 Negative Genetic, Negative Genetic
CDC25 YLR310C Membrane bound guanine nucleotide exchange factor physical 2 2 1 Affinity Capture-Western, Biochemical Activity
NBA1 YOL070C Protein involved in axial bud site selection physical 2 2 1 Reconstituted Complex, Affinity Capture-Western
NSL1 YPL233W Essential component of the MIND kinetochore complex physical 2 2 1 Reconstituted Complex, Affinity Capture-Western
PTC1 YDL006W Type 2C protein phosphatase (PP2C) physical 2 2 1 Reconstituted Complex, Affinity Capture-Western
PTP1 YDL230W Phosphotyrosine-specific protein phosphatase physical 2 2 1 Reconstituted Complex, Affinity Capture-Western
SNU71 YGR013W Component of U1 snRNP required for mRNA splicing via spliceosome physical 2 2 1 Reconstituted Complex, Affinity Capture-Western
POF1 YCL047C Nicotinamide mononucleotide-specific adenylyltransferase (NMNAT) physical 2 2 1 Reconstituted Complex, Affinity Capture-Western
SLT2 YHR030C Serine/threonine MAP kinase genetic 2 2 1 Dosage Rescue, Synthetic Growth Defect
CAF16 YFL028C Part of evolutionarily-conserved CCR4-NOT regulatory complex physical 2 2 1 Reconstituted Complex, Affinity Capture-Western
CTA1 YDR256C Catalase A physical 2 2 1 Reconstituted Complex, Affinity Capture-Western
CDC37 YDR168W Essential Hsp90p co-chaperone physical 2 1 1 Affinity Capture-Western, Affinity Capture-Western
MPT5 YGL178W mRNA-binding protein of the PUF family physical 2 1 1 Two-hybrid, Two-hybrid
TFC7 YOR110W RNA pol III transcription initiation factor complex (TFIIIC) subunit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CKA2 YOR061W Alpha' catalytic subunit of casein kinase 2 (CK2) genetic 1 1 1 Positive Genetic
CKB1 YGL019W Beta regulatory subunit of casein kinase 2 (CK2) genetic 1 1 1 Negative Genetic
DRS1 YLL008W Nucleolar DEAD-box protein required for ribosome assembly and function physical 1 1 1 Biochemical Activity
HAS1 YMR290C ATP-dependent RNA helicase physical 1 1 1 Affinity Capture-MS
CDC42 YLR229C Small rho-like GTPase genetic 1 1 1 Negative Genetic
FRT2 YAL028W Tail-anchored ER membrane protein of unknown function physical 1 1 1 Biochemical Activity
ARC1 YGL105W Protein that binds tRNA and methionyl- and glutamyl-tRNA synthetases physical 1 1 1 Biochemical Activity
ARP7 YPR034W Component of both the SWI/SNF and RSC chromatin remodeling complexes physical 1 1 1 Affinity Capture-MS
IMD2 YHR216W Inosine monophosphate dehydrogenase physical 1 1 1 Biochemical Activity
AAH1 YNL141W Adenine deaminase (adenine aminohydrolase) genetic 1 1 1 Negative Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
AOS1 YPR180W Subunit of heterodimeric nuclear SUMO activating enzyme E1 with Uba2p genetic 1 1 1 Negative Genetic
BEM1 YBR200W Protein containing SH3-domains genetic 1 1 1 Negative Genetic
CAF40 YNL288W Component of the CCR4-NOT transcriptional complex physical 1 1 1 Biochemical Activity
CDC14 YFR028C Protein phosphatase required for mitotic exit physical 1 1 1 Affinity Capture-Western
CDC10 YCR002C Component of the septin ring, required for cytokinesis genetic 1 1 1 Dosage Rescue
CDC55 YGL190C Regulatory subunit B of protein phosphatase 2A (PP2A) genetic 1 1 1 Positive Genetic
AVO1 YOL078W Component of the membrane-bound TORC2 complex physical 1 1 1 Affinity Capture-MS
COX6 YHR051W Subunit VI of cytochrome c oxidase (Complex IV) genetic 1 1 1 Negative Genetic
CYS4 YGR155W Cystathionine beta-synthase physical 1 1 1 Affinity Capture-MS
BDF2 YDL070W Protein involved in transcription initiation physical 1 1 1 Biochemical Activity
HIF1 YLL022C Non-essential component of the HAT-B histone acetyltransferase complex physical 1 1 1 Biochemical Activity
HSM3 YBR272C Evolutionarily conserved 19S regulatory particle assembly-chaperone physical 1 1 1 Biochemical Activity
GFA1 YKL104C Glutamine-fructose-6-phosphate amidotransferase physical 1 1 1 Affinity Capture-MS
HSP82 YPL240C Hsp90 chaperone physical 1 1 1 Two-hybrid
ABF2 YMR072W Mitochondrial DNA-binding protein genetic 1 1 1 Negative Genetic
CCT2 YIL142W Subunit beta of the cytosolic chaperonin Cct ring complex physical 1 1 1 Affinity Capture-MS
CAM1 YPL048W One of two isoforms of the gamma subunit of eEF1B physical 1 1 1 Biochemical Activity
GLN1 YPR035W Glutamine synthetase (GS) physical 1 1 1 Reconstituted Complex
HEK2 YBL032W RNA binding protein involved in asymmetric localization of ASH1 mRNA physical 1 1 1 Affinity Capture-RNA
AIM17 YHL021C Protein of unknown function physical 1 1 1 Biochemical Activity
ACO1 YLR304C Aconitase physical 1 1 1 Affinity Capture-MS
FET4 YMR319C Low-affinity Fe(II) transporter of the plasma membrane physical 1 1 1 Affinity Capture-MS
ADO1 YJR105W Adenosine kinase physical 1 1 1 Biochemical Activity
GSF2 YML048W Endoplasmic reticulum (ER) localized integral membrane protein physical 1 1 1 Reconstituted Complex
HXT6 YDR343C High-affinity glucose transporter physical 1 1 1 Affinity Capture-MS
FAR1 YJL157C CDK inhibitor and nuclear anchor genetic 1 1 1 Phenotypic Suppression
KDX1 YKL161C Protein kinase physical 1 1 1 Affinity Capture-MS
ELM1 YKL048C Serine/threonine protein kinase genetic 1 1 1 Phenotypic Suppression
GPA2 YER020W Nucleotide binding alpha subunit of the heterotrimeric G protein physical 1 1 1 Affinity Capture-Western
FAR10 YLR238W Protein involved in recovery from arrest in response to pheromone genetic 1 1 1 Negative Genetic
BEM4 YPL161C Protein involved in establishment of cell polarity and bud emergence physical 1 1 1 Affinity Capture-Western
RVB1 YDR190C ATP-dependent DNA helicase, also known as pontin physical 1 1 1 Affinity Capture-MS
RNH203 YLR154C Ribonuclease H2 subunit physical 1 1 1 Affinity Capture-MS
NPA3 YJR072C Member of the conserved GPN-loop GTPase family physical 1 1 1 Affinity Capture-MS
RPA135 YPR010C RNA polymerase I second largest subunit A135 physical 1 1 1 Affinity Capture-MS
RPN6 YDL097C Essential, non-ATPase regulatory subunit of the 26S proteasome lid physical 1 1 1 Affinity Capture-MS
PIM1 YBL022C ATP-dependent Lon protease physical 1 1 1 Affinity Capture-MS
YDR239C YDR239C Protein of unknown function physical 1 1 1 Affinity Capture-MS
UBI4 YLL039C Ubiquitin physical 1 1 1 Affinity Capture-MS
YHR033W YHR033W Putative protein of unknown function physical 1 1 1 Affinity Capture-MS
PMA1 YGL008C Plasma membrane P2-type H+-ATPase physical 1 1 1 Affinity Capture-MS
PYC1 YGL062W Pyruvate carboxylase isoform physical 1 1 1 Affinity Capture-MS
MKT1 YNL085W Protein similar to nucleases that forms a complex with Pbp1p physical 1 1 1 Affinity Capture-MS
MSE1 YOL033W Mitochondrial glutamyl-tRNA synthetase physical 1 1 1 Affinity Capture-MS
SEN1 YLR430W ATP-dependent 5' to 3' RNA/DNA and DNA helicase physical 1 1 1 Affinity Capture-MS
RPN10 YHR200W Proteasome polyubiquitin receptor physical 1 1 1 Affinity Capture-MS
PHO84 YML123C High-affinity inorganic phosphate (Pi) transporter physical 1 1 1 Affinity Capture-MS
SST2 YLR452C GTPase-activating protein for Gpa1p physical 1 1 1 Two-hybrid
NOT5 YPR072W Component of the CCR4-NOT core complex, involved in mRNA decapping physical 1 1 1 Biochemical Activity
RRP5 YMR229C RNA binding protein involved in synthesis of 18S and 5.8S rRNAs physical 1 1 1 Biochemical Activity
NOT3 YIL038C Component of the CCR4-NOT core complex, involved in mRNA decapping physical 1 1 1 Biochemical Activity
SIP4 YJL089W C6 zinc cluster transcriptional activator physical 1 1 1 Biochemical Activity
SPT6 YGR116W Nucleosome remodeling protein physical 1 1 1 Biochemical Activity
MCM2 YBL023C Protein involved in DNA replication physical 1 1 1 Biochemical Activity
MRM2 YGL136C Mitochondrial 2' O-ribose methyltransferase physical 1 1 1 Biochemical Activity
OSH7 YHR001W Oxysterol-binding phosphatidylserine transferase physical 1 1 1 Biochemical Activity
MRP8 YKL142W Protein of unknown function physical 1 1 1 Biochemical Activity
SPT15 YER148W TATA-binding protein (TBP) physical 1 1 1 Biochemical Activity
VPS27 YNR006W Endosomal protein that forms a complex with Hse1p physical 1 1 1 Biochemical Activity
YSP3 YOR003W Putative precursor of the subtilisin-like protease III physical 1 1 1 Biochemical Activity
YDR034C-C YDR034C-C Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Biochemical Activity
SEC2 YNL272C Guanyl-nucleotide exchange factor for the small G-protein Sec4p physical 1 1 1 Biochemical Activity
PEX30 YLR324W ER-resident protein involved in peroxisomal biogenesis physical 1 1 1 Biochemical Activity
YHM2 YMR241W Citrate and oxoglutarate carrier protein physical 1 1 1 Biochemical Activity
NVJ2 YPR091C Lipid-binding ER protein, enriched at nucleus-vacuolar junctions (NVJ) physical 1 1 1 Biochemical Activity
PDI1 YCL043C Protein disulfide isomerase physical 1 1 1 Biochemical Activity
YGR016W YGR016W Putative protein of unknown function physical 1 1 1 Biochemical Activity
PAC10 YGR078C Part of the heteromeric co-chaperone GimC/prefoldin complex physical 1 1 1 Biochemical Activity
RPL26B YGR034W Ribosomal 60S subunit protein L26B physical 1 1 1 Biochemical Activity
NCL1 YBL024W S-adenosyl-L-methionine-dependent tRNA: m5C-methyltransferase physical 1 1 1 Biochemical Activity
RNT1 YMR239C Nuclear dsRNA-specific ribonuclease (RNase III) physical 1 1 1 Biochemical Activity
SAS10 YDL153C Subunit of U3-containing Small Subunit (SSU) processome complex physical 1 1 1 Biochemical Activity
SLA1 YBL007C Cytoskeletal protein binding protein physical 1 1 1 Biochemical Activity
UBP9 YER098W Ubiquitin-specific protease that cleaves ubiquitin-protein fusions physical 1 1 1 Biochemical Activity
SSF2 YDR312W Protein required for ribosomal large subunit maturation physical 1 1 1 Biochemical Activity
YJR142W YJR142W 8-oxo-dGTP diphosphatase of the Nudix hydrolase family physical 1 1 1 Biochemical Activity
TOS1 YBR162C Covalently-bound cell wall protein of unknown function physical 1 1 1 Biochemical Activity
VCX1 YDL128W Vacuolar membrane antiporter with Ca2+/H+ and K+/H+ exchange activity physical 1 1 1 Biochemical Activity
MAM33 YIL070C Acidic protein of the mitochondrial matrix physical 1 1 1 Biochemical Activity
UBP10 YNL186W Ubiquitin-specific protease, deubiquitinates Ub-protein moieties physical 1 1 1 Biochemical Activity
YPR137C-A YPR137C-A Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Biochemical Activity
TAD3 YLR316C Subunit of tRNA-specific adenosine-34 deaminase physical 1 1 1 Biochemical Activity
YNL054W-A YNL054W-A Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Biochemical Activity
RNH70 YGR276C 3'-5' exoribonuclease physical 1 1 1 Biochemical Activity
TCA17 YEL048C Component of transport protein particle (TRAPP) complex II physical 1 1 1 Two-hybrid
KSS1 YGR040W Mitogen-activated protein kinase (MAPK) physical 1 1 1 PCA
MLS1 YNL117W Malate synthase, enzyme of the glyoxylate cycle physical 1 1 1 Reconstituted Complex
NSL1 YPL233W Essential component of the MIND kinetochore complex genetic 1 1 1 Phenotypic Suppression
PTC1 YDL006W Type 2C protein phosphatase (PP2C) genetic 1 1 1 Phenotypic Suppression
RNR4 YGR180C Ribonucleotide-diphosphate reductase (RNR) small subunit physical 1 1 1 Reconstituted Complex
YBL055C YBL055C 3'-->5' exonuclease and endonuclease with a possible role in apoptosis physical 1 1 1 Reconstituted Complex
POF1 YCL047C Nicotinamide mononucleotide-specific adenylyltransferase (NMNAT) genetic 1 1 1 Phenotypic Suppression
LIA1 YJR070C Deoxyhypusine hydroxylase physical 1 1 1 Reconstituted Complex
MIG1 YGL035C Transcription factor involved in glucose repression physical 1 1 1 Two-hybrid
MIG2 YGL209W Zinc finger transcriptional repressor physical 1 1 1 Two-hybrid
NAM7 YMR080C ATP-dependent RNA helicase of the SFI superfamily physical 1 1 1 Affinity Capture-RNA
SPT10 YJL127C Histone H3 acetylase with a role in transcriptional regulation physical 1 1 1 Affinity Capture-MS
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
OCH1 YGL038C Mannosyltransferase of the cis-Golgi apparatus genetic 1 1 1 Dosage Lethality
STE4 YOR212W G protein beta subunit genetic 1 1 1 Phenotypic Enhancement
MSS11 YMR164C Transcription factor genetic 1 1 1 Dosage Rescue
TPK1 YJL164C cAMP-dependent protein kinase catalytic subunit genetic 1 1 1 Phenotypic Suppression
TPK3 YKL166C cAMP-dependent protein kinase catalytic subunit genetic 1 1 1 Phenotypic Suppression
MCM1 YMR043W Transcription factor genetic 1 1 1 Phenotypic Suppression
PIK1 YNL267W Phosphatidylinositol 4-kinase genetic 1 1 1 Phenotypic Suppression
REI1 YBR267W Cytoplasmic pre-60S factor genetic 1 1 1 Negative Genetic
SBA1 YKL117W Co-chaperone that binds and regulates Hsp90 family chaperones genetic 1 1 1 Synthetic Lethality
UPC2 YDR213W Sterol regulatory element binding protein genetic 1 1 1 Negative Genetic
YER138C YER138C Retrotransposon TYA Gag and TYB Pol genes genetic 1 1 1 Dosage Growth Defect
SWI6 YLR182W Transcription cofactor genetic 1 1 1 Dosage Growth Defect
REB1 YBR049C RNA polymerase I enhancer binding protein genetic 1 1 1 Positive Genetic
MMT2 YPL224C Putative metal transporter involved in mitochondrial iron accumulation genetic 1 1 1 Positive Genetic
NFS1 YCL017C Cysteine desulfurase involved in iron-sulfur cluster biogenesis genetic 1 1 1 Negative Genetic
NSE4 YDL105W Component of the SMC5-SMC6 complex genetic 1 1 1 Negative Genetic
MED4 YOR174W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
SCO1 YBR037C Copper-binding protein of mitochondrial inner membrane genetic 1 1 1 Negative Genetic
YDL012C YDL012C Tail-anchored plasma membrane protein with a conserved CYSTM module genetic 1 1 1 Negative Genetic
MNN10 YDR245W Subunit of a Golgi mannosyltransferase complex genetic 1 1 1 Negative Genetic
RVS167 YDR388W Calmodulin-binding actin-associated protein genetic 1 1 1 Negative Genetic
YHP1 YDR451C Homeobox transcriptional repressor genetic 1 1 1 Negative Genetic
STL1 YDR536W Glycerol proton symporter of the plasma membrane genetic 1 1 1 Negative Genetic
NMD2 YHR077C Protein involved in the nonsense-mediated mRNA decay (NMD) pathway genetic 1 1 1 Negative Genetic
TUS1 YLR425W Guanine nucleotide exchange factor (GEF) that modulates Rho1p activity genetic 1 1 1 Negative Genetic
VAN1 YML115C Component of the mannan polymerase I genetic 1 1 1 Negative Genetic
RIM101 YHL027W Cys2His2 zinc-finger transcriptional repressor genetic 1 1 1 Dosage Rescue
SLA2 YNL243W Adaptor protein that links actin to clathrin and endocytosis genetic 1 1 1 Negative Genetic
SCH9 YHR205W AGC family protein kinase genetic 1 1 1 Negative Genetic
SPE1 YKL184W Ornithine decarboxylase genetic 1 1 1 Positive Genetic
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p) genetic 1 1 1 Negative Genetic
SPE2 YOL052C S-adenosylmethionine decarboxylase genetic 1 1 1 Positive Genetic
VPS53 YJL029C Component of the GARP (Golgi-associated retrograde protein) complex genetic 1 1 1 Negative Genetic
TOR1 YJR066W PIK-related protein kinase and rapamycin target genetic 1 1 1 Phenotypic Enhancement
TUB4 YLR212C Gamma-tubulin genetic 1 1 1 Synthetic Rescue
GCR2 YNL199C Transcriptional activator of genes involved in glycolysis genetic 1 1 1 Negative Genetic
BIR1 YJR089W Subunit of chromosomal passenger complex (CPC) genetic 1 1 1 Negative Genetic
DUO1 YGL061C Essential subunit of the Dam1 complex (aka DASH complex) physical 1 1 1 Biochemical Activity
HOF1 YMR032W F-BAR protein that regulates actin cytoskeleton organization physical 1 1 1 PCA
BUD27 YFL023W Unconventional prefoldin protein involved in translation initiation physical 1 1 1 Biochemical Activity
CLN3 YAL040C G1 cyclin involved in cell cycle progression genetic 1 1 1 Phenotypic Suppression
BIM1 YER016W Microtubule plus end-tracking protein genetic 1 1 1 Phenotypic Enhancement
ASK10 YGR097W Regulator of the Fps1p glycerol channel physical 1 1 1 Affinity Capture-MS
GMH1 YKR030W Golgi membrane protein of unknown function genetic 1 1 1 Negative Genetic
CST6 YIL036W Basic leucine zipper (bZIP) transcription factor from ATF/CREB family physical 1 1 1 Biochemical Activity
BUB1 YGR188C Protein kinase involved in the cell cycle checkpoint into anaphase genetic 1 1 1 Negative Genetic
EMP47 YFL048C Integral membrane component of ER-derived COPII-coated vesicles physical 1 1 1 Biochemical Activity
CAF16 YFL028C Part of evolutionarily-conserved CCR4-NOT regulatory complex genetic 1 1 1 Phenotypic Suppression
AKR1 YDR264C Palmitoyl transferase involved in protein palmitoylation genetic 1 1 1 Synthetic Rescue
BET4 YJL031C Alpha subunit of Type II geranylgeranyltransferase genetic 1 1 1 Negative Genetic
FLO8 YER109C Transcription factor genetic 1 1 1 Dosage Rescue
ASG1 YIL130W Zinc cluster protein proposed to be a transcriptional regulator physical 1 1 1 Biochemical Activity
ABZ1 YNR033W Para-aminobenzoate (PABA) synthase physical 1 1 1 Reconstituted Complex
IXR1 YKL032C Transcriptional repressor that regulates hypoxic genes during normoxia genetic 1 1 1 Negative Genetic
HAM1 YJR069C Nucleoside triphosphate pyrophosphohydrolase physical 1 1 1 Biochemical Activity
ARA2 YMR041C NAD-dependent arabinose dehydrogenase physical 1 1 1 Reconstituted Complex
GCD14 YJL125C Subunit of tRNA (1-methyladenosine) methyltransferase genetic 1 1 1 Negative Genetic
APJ1 YNL077W Hsp40 chaperone with a role in SUMO-mediated protein degradation physical 1 1 1 Biochemical Activity
CDA1 YLR307W Chitin deacetylase physical 1 1 1 Biochemical Activity
HXT10 YFL011W Hexose transporter physical 1 1 1 Biochemical Activity
ABM1 YJR108W Protein of unknown function physical 1 1 1 Biochemical Activity
DLD2 YDL178W D-2-hydroxyglutarate dehydrogenase, and minor D-lactate dehydrogenase physical 1 1 1 Biochemical Activity
IRC5 YFR038W Putative ATPase containing the DEAD/H helicase-related sequence motif physical 1 1 1 Biochemical Activity
DGA1 YOR245C Diacylglycerol acyltransferase physical 1 1 1 Biochemical Activity
GGC1 YDL198C Mitochondrial GTP/GDP transporter physical 1 1 1 Biochemical Activity
ALK1 YGL021W Atypical protein kinase genetic 1 1 1 Negative Genetic