Standard name Systematic name Name description Description
HOF1 YMR032W F-BAR protein that regulates actin cytoskeleton organization F-BAR protein that regulates actin cytoskeleton organization; binds and bundles actin filaments, linking them to septins; required for cytokinesis, actin cable organization, and secretory vesicle trafficking; regulates actomyosin ring dynamics and septin localization; N-term. half controls cell size and actin cable levels, while the C-term. half controls actin cable organization, inhibiting Bnr1p-mediated actin nucleation; forms axial striations/pillars at the bud neck; phosphorylated by Dbf2p
Visualize the interactome of HOF1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)
G2/M 138

CYCLoPs localization & abundance

WT1 WT2 WT3
Budneck 0.059 0.101 0.059
Budsite 0.076 0.090 0.059
Cytoplasm 0.636 0.584 0.824
Mito 0.076 NaN 0.059
Peroxisome 0.076 0.056 NaN
SpindlePole 0.119 0.084 NaN
Endosome NaN 0.051 NaN
Vac/Vac Memb NaN 0.056 0.059
Nucleus NaN NaN 0.059

GFP localization & abundance

GFP localization GFP abundance
bud neck 195

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
HOF1 0 0 10 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
INN1 YNL152W Essential protein that associates with contractile actomyosin ring physical 17 5 14 Two-hybrid, Two-hybrid, Two-hybrid, Affinity Capture-MS, Affinity Capture-Western, Two-hybrid, Two-hybrid, Affinity Capture-Western, Two-hybrid, Two-hybrid, PCA, Two-hybrid, Reconstituted Complex, Two-hybrid, Affinity Capture-MS, Two-hybrid, Two-hybrid
CYK3 YDL117W SH3-domain protein located in the bud neck and cytokinetic actin ring genetic 17 5 12 Synthetic Lethality, Synthetic Lethality, Dosage Rescue, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Positive Genetic, Dosage Rescue, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Phenotypic Enhancement, Phenotypic Enhancement, Synthetic Lethality, Dosage Rescue, Synthetic Lethality, Phenotypic Suppression
CYK3 YDL117W SH3-domain protein located in the bud neck and cytokinetic actin ring physical 11 5 6 Two-hybrid, Two-hybrid, Two-hybrid, PCA, PCA, Reconstituted Complex, Two-hybrid, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western, Co-localization
BNR1 YIL159W Formin physical 6 2 4 Reconstituted Complex, Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Reconstituted Complex
FKH2 YNL068C Forkhead family transcription factor regulation 5 3 5 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation- exonuclease evidence, chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation- exonuclease evidence, ChEC-Seq experiments
MYO1 YHR023W Type II myosin heavy chain genetic 5 3 5 Synthetic Lethality, Dosage Rescue, Synthetic Lethality, Synthetic Growth Defect, Synthetic Lethality
INN1 YNL152W Essential protein that associates with contractile actomyosin ring genetic 4 3 4 Synthetic Lethality, Dosage Rescue, Synthetic Growth Defect, Dosage Rescue
CDC10 YCR002C Component of the septin ring, required for cytokinesis physical 4 3 3 Two-hybrid, PCA, Affinity Capture-Western, Two-hybrid
VRP1 YLR337C Verprolin, proline-rich actin-associated protein physical 4 2 3 Reconstituted Complex, Two-hybrid, Two-hybrid, Reconstituted Complex
SPA2 YLL021W Component of the polarisome physical 4 3 1 Affinity Capture-Western, Two-hybrid, Two-hybrid, Reconstituted Complex
CHS2 YBR038W Chitin synthase II genetic 3 2 3 Dosage Rescue, Dosage Rescue, Synthetic Rescue
LAS17 YOR181W Actin assembly factor physical 3 1 3 Two-hybrid, Two-hybrid, Two-hybrid
GIN4 YDR507C Protein kinase involved in bud growth and assembly of the septin ring genetic 3 3 2 Synthetic Lethality, Phenotypic Enhancement, Dosage Rescue
SHO1 YER118C Transmembrane osmosensor for filamentous growth and HOG pathways physical 3 3 2 Two-hybrid, PCA, Reconstituted Complex
RVS167 YDR388W Calmodulin-binding actin-associated protein genetic 3 3 2 Positive Genetic, Synthetic Lethality, Phenotypic Enhancement
SHS1 YDL225W Component of the septin ring that is required for cytokinesis genetic 3 2 2 Synthetic Lethality, Phenotypic Enhancement, Synthetic Lethality
UBP5 YER144C Putative ubiquitin-specific protease physical 3 1 2 Two-hybrid, Two-hybrid, Two-hybrid
CDC5 YMR001C Polo-like kinase required for mitotic exit physical 3 3 1 Two-hybrid, Co-localization, Biochemical Activity
GRR1 YJR090C F-box protein component of an SCF ubiquitin-ligase complex physical 3 3 1 Two-hybrid, PCA, FRET
SKT5 YBL061C Activator of Chs3p (chitin synthase III) during vegetative growth physical 3 3 1 Two-hybrid, Reconstituted Complex, PCA
FKH1 YIL131C Forkhead family transcription factor regulation 2 2 2 chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments
CDC42 YLR229C Small rho-like GTPase genetic 2 2 2 Negative Genetic, Dosage Growth Defect
CDC12 YHR107C Component of the septin ring that is required for cytokinesis physical 2 2 2 PCA, Two-hybrid
BOI1 YBL085W Protein involved in polar growth, functionally redundant with Boi2p physical 2 2 2 Two-hybrid, PCA
DBF20 YPR111W Ser/Thr kinase involved in late nuclear division genetic 2 2 2 Synthetic Growth Defect, Phenotypic Suppression
ELM1 YKL048C Serine/threonine protein kinase genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
DBF2 YGR092W Ser/Thr kinase involved in transcription and stress response genetic 2 2 2 Synthetic Growth Defect, Phenotypic Suppression
NBA1 YOL070C Protein involved in axial bud site selection physical 2 2 2 Two-hybrid, PCA
MYO1 YHR023W Type II myosin heavy chain physical 2 2 2 Reconstituted Complex, Affinity Capture-Western
IQG1 YPL242C Actin filament binding protein that enhances actin ring formation physical 2 2 2 PCA, Affinity Capture-MS
YPC1 YBR183W Alkaline ceramidase genetic 2 2 2 Positive Genetic, Negative Genetic
PSP1 YDR505C Asn and gln rich protein of unknown function genetic 2 2 2 Negative Genetic, Dosage Rescue
CHS3 YBR023C Chitin synthase III genetic 2 2 2 Negative Genetic, Phenotypic Suppression
AIM44 YPL158C Regulator of Cdc42p and Rho1p physical 2 2 2 Two-hybrid, Affinity Capture-Western
CHS2 YBR038W Chitin synthase II physical 2 2 2 Reconstituted Complex, Affinity Capture-MS
BBC1 YJL020C Protein possibly involved in assembly of actin patches physical 2 1 2 Two-hybrid, Two-hybrid
CDC15 YAR019C Hippo-like kinase of the Mitotic Exit Network genetic 2 1 2 Phenotypic Enhancement, Phenotypic Enhancement
SAP1 YER047C Putative ATPase of the AAA family physical 2 1 2 Two-hybrid, Two-hybrid
RIM101 YHL027W Cys2His2 zinc-finger transcriptional repressor physical 2 1 2 Two-hybrid, Two-hybrid
RGD1 YBR260C GTPase-activating protein (RhoGAP) for Rho3p and Rho4p physical 2 1 2 Two-hybrid, Two-hybrid
CDC11 YJR076C Component of the septin ring that is required for cytokinesis physical 2 2 1 Reconstituted Complex, PCA
DBF2 YGR092W Ser/Thr kinase involved in transcription and stress response physical 2 2 1 Co-localization, Biochemical Activity
MOB1 YIL106W Component of the mitotic exit network physical 2 2 1 Two-hybrid, Affinity Capture-Western
HDA1 YNL021W Catalytic subunit of class II HDA1 histone deacetylase complex genetic 2 1 1 Dosage Lethality, Dosage Lethality
DYN1 YKR054C Cytoplasmic heavy chain dynein genetic 2 1 1 Positive Genetic, Positive Genetic
GIM5 YML094W Subunit of the heterohexameric cochaperone prefoldin complex genetic 2 1 1 Positive Genetic, Positive Genetic
ATG29 YPL166W Autophagy-specific protein genetic 2 1 1 Positive Genetic, Positive Genetic
ARE2 YNR019W Acyl-CoA:sterol acyltransferase genetic 2 1 1 Positive Genetic, Positive Genetic
CAF4 YKR036C WD40 repeat-containing protein associated with the CCR4-NOT complex genetic 2 1 1 Positive Genetic, Positive Genetic
OPI3 YJR073C Methylene-fatty-acyl-phospholipid synthase genetic 2 1 1 Negative Genetic, Negative Genetic
ILM1 YJR118C Protein of unknown function genetic 2 1 1 Positive Genetic, Positive Genetic
LAC1 YKL008C Ceramide synthase component genetic 2 1 1 Negative Genetic, Negative Genetic
MCR1 YKL150W Mitochondrial NADH-cytochrome b5 reductase genetic 2 1 1 Positive Genetic, Positive Genetic
SAC1 YKL212W Phosphatidylinositol phosphate phosphatase genetic 2 1 1 Negative Genetic, Negative Genetic
MIC60 YKR016W Component of the MICOS complex genetic 2 1 1 Negative Genetic, Negative Genetic
UTH1 YKR042W Mitochondrial inner membrane protein genetic 2 1 1 Negative Genetic, Negative Genetic
PER33 YLR064W Protein that localizes to the endoplasmic reticulum genetic 2 1 1 Positive Genetic, Positive Genetic
SEC72 YLR292C Non-essential subunit of Sec63 complex genetic 2 1 1 Negative Genetic, Negative Genetic
VPS71 YML041C Nucleosome-binding component of the SWR1 complex genetic 2 1 1 Positive Genetic, Positive Genetic
SPC2 YML055W Subunit of signal peptidase complex genetic 2 1 1 Positive Genetic, Positive Genetic
PKR1 YMR123W V-ATPase assembly factor genetic 2 1 1 Positive Genetic, Positive Genetic
YIM1 YMR152W Aldehyde reductase genetic 2 1 1 Positive Genetic, Positive Genetic
MLH1 YMR167W Protein required for mismatch repair in mitosis and meiosis genetic 2 1 1 Positive Genetic, Positive Genetic
SCS7 YMR272C Sphingolipid alpha-hydroxylase genetic 2 1 1 Positive Genetic, Positive Genetic
SLM2 YNL047C Phosphoinositide PI4,5P(2) binding protein, forms a complex with Slm1p genetic 2 1 1 Positive Genetic, Positive Genetic
YDJ1 YNL064C Type I HSP40 co-chaperone genetic 2 1 1 Negative Genetic, Negative Genetic
MIC27 YNL100W Component of the MICOS complex genetic 2 1 1 Positive Genetic, Positive Genetic
PSD1 YNL169C Phosphatidylserine decarboxylase of the mitochondrial inner membrane genetic 2 1 1 Positive Genetic, Positive Genetic
LEM3 YNL323W Membrane protein of the plasma membrane and ER genetic 2 1 1 Positive Genetic, Positive Genetic
HTZ1 YOL012C Histone variant H2AZ genetic 2 1 1 Positive Genetic, Positive Genetic
TLG2 YOL018C Syntaxin-like t-SNARE genetic 2 1 1 Negative Genetic, Negative Genetic
IZH4 YOL101C Membrane protein involved in zinc ion homeostasis genetic 2 1 1 Positive Genetic, Positive Genetic
INO4 YOL108C Transcription factor involved in phospholipid synthesis genetic 2 1 1 Positive Genetic, Positive Genetic
TIM18 YOR297C Component of the mitochondrial TIM22 complex genetic 2 1 1 Positive Genetic, Positive Genetic
MSC6 YOR354C Multicopy suppressor of HER2 involved in mitochondrial translation genetic 2 1 1 Positive Genetic, Positive Genetic
SUR1 YPL057C Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit genetic 2 1 1 Positive Genetic, Positive Genetic
UBP16 YPL072W Deubiquitinating enzyme anchored to the outer mitochondrial membrane genetic 2 1 1 Positive Genetic, Positive Genetic
YME1 YPR024W Catalytic subunit of i-AAA protease complex genetic 2 1 1 Positive Genetic, Positive Genetic
SYT1 YPR095C Guanine nucleotide exchange factor (GEF) for Arf proteins genetic 2 1 1 Negative Genetic, Negative Genetic
NCE102 YPR149W Protein of unknown function genetic 2 1 1 Positive Genetic, Positive Genetic
POP2 YNR052C Subunit of Ccr4-Not complex that mediates 3' to 5' mRNA deadenylation genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
ATG13 YPR185W Regulatory subunit of the Atg1p signaling complex genetic 2 1 1 Positive Genetic, Positive Genetic
CPT1 YNL130C Cholinephosphotransferase genetic 2 1 1 Positive Genetic, Positive Genetic
GYP1 YOR070C Cis-golgi GTPase-activating protein (GAP) for yeast Rabs genetic 2 1 1 Positive Genetic, Positive Genetic
ATG10 YLL042C Conserved E2-like conjugating enzyme genetic 2 1 1 Positive Genetic, Positive Genetic
CSF1 YLR087C Protein with structural similarity to lipid transport protein Vps13p genetic 2 1 1 Positive Genetic, Positive Genetic
ARV1 YLR242C Cortical ER protein genetic 2 1 1 Negative Genetic, Negative Genetic
CYC1 YJR048W Cytochrome c, isoform 1 genetic 2 1 1 Positive Genetic, Positive Genetic
DYN3 YMR299C Dynein light intermediate chain (LIC) genetic 2 1 1 Positive Genetic, Positive Genetic
DDL1 YOR022C DDHD domain-containing phospholipase A1 genetic 2 1 1 Positive Genetic, Positive Genetic
EMA19 YLR050C Integral ER membrane protein involved in protein sorting genetic 2 1 1 Positive Genetic, Positive Genetic
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
HFI1 YPL254W Adaptor protein required for structural integrity of the SAGA complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MED2 YDL005C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MSN2 YMR037C Stress-responsive transcriptional activator regulation 1 1 1 RNA-sequencing evidence
XBP1 YIL101C Transcriptional repressor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAP1 YML007W Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SUA7 YPR086W Transcription factor TFIIB regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MSN4 YKL062W Stress-responsive transcriptional activator regulation 1 1 1 RNA-sequencing evidence
SPT3 YDR392W Subunit of the SAGA and SAGA-like transcriptional regulatory complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
FHL1 YPR104C Regulator of ribosomal protein (RP) transcription regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SPT6 YGR116W Nucleosome remodeling protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
UME6 YDR207C Rpd3L histone deacetylase complex subunit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
TUP1 YCR084C General repressor of transcription in complex with Cyc8p regulation 1 1 1 chromatin immunoprecipitation-chip evidence
UGA3 YDL170W Transcriptional activator for GABA-dependent induction of GABA genes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ARG80 YMR042W Transcription factor involved in regulating arginine-responsive genes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RPH1 YER169W JmjC domain-containing histone demethylase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
BMH1 YER177W 14-3-3 protein, major isoform genetic 1 1 1 Positive Genetic
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 1 1 1 Phenotypic Suppression
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
ATG14 YBR128C Autophagy-specific subunit of phosphatidylinositol 3-kinase complex I genetic 1 1 1 Positive Genetic
ARC18 YLR370C Subunit of the ARP2/3 complex genetic 1 1 1 Positive Genetic
BET2 YPR176C Beta subunit of Type II geranylgeranyltransferase genetic 1 1 1 Positive Genetic
CDC14 YFR028C Protein phosphatase required for mitotic exit genetic 1 1 1 Phenotypic Enhancement
CDC24 YAL041W Guanine nucleotide exchange factor (GEF) for Cdc42p genetic 1 1 1 Dosage Rescue
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit physical 1 1 1 Biochemical Activity
CDC3 YLR314C Component of the septin ring that is required for cytokinesis physical 1 1 1 PCA
ERG26 YGL001C C-3 sterol dehydrogenase genetic 1 1 1 Positive Genetic
BNI1 YNL271C Formin physical 1 1 1 Two-hybrid
BNI1 YNL271C Formin genetic 1 1 1 Synthetic Lethality
CYS4 YGR155W Cystathionine beta-synthase genetic 1 1 1 Positive Genetic
DCP1 YOL149W Subunit of the Dcp1p-Dcp2p decapping enzyme complex genetic 1 1 1 Positive Genetic
DOA1 YKL213C WD-repeat protein involved in ubiquitin-mediated protein degradation genetic 1 1 1 Positive Genetic
EDE1 YBL047C Scaffold protein involved in the formation of early endocytic sites genetic 1 1 1 Phenotypic Enhancement
GCD7 YLR291C Beta subunit of translation initiation factor eIF2B physical 1 1 1 Two-hybrid
HAP2 YGL237C Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex genetic 1 1 1 Positive Genetic
HHF1 YBR009C Histone H4 genetic 1 1 1 Positive Genetic
EHD3 YDR036C 3-hydroxyisobutyryl-CoA hydrolase genetic 1 1 1 Negative Genetic
GPT2 YKR067W Glycerol-3-phosphate/dihydroxyacetone phosphate sn-1 acyltransferase genetic 1 1 1 Positive Genetic
BCK1 YJL095W MAPKKK acting in the protein kinase C signaling pathway genetic 1 1 1 Negative Genetic
BRO1 YPL084W Cytoplasmic class E vacuolar protein sorting (VPS) factor physical 1 1 1 Two-hybrid
BBC1 YJL020C Protein possibly involved in assembly of actin patches genetic 1 1 1 Positive Genetic
CDC5 YMR001C Polo-like kinase required for mitotic exit genetic 1 1 1 Synthetic Growth Defect
GPP1 YIL053W Constitutively expressed DL-glycerol-3-phosphate phosphatase genetic 1 1 1 Positive Genetic
APP1 YNL094W Phosphatidate phosphatase, converts phosphatidate to diacylglycerol physical 1 1 1 Two-hybrid
HIR3 YJR140C Subunit of the HIR complex genetic 1 1 1 Positive Genetic
CNB1 YKL190W Calcineurin B genetic 1 1 1 Positive Genetic
FKH1 YIL131C Forkhead family transcription factor genetic 1 1 1 Positive Genetic
BUD13 YGL174W Subunit of the RES complex genetic 1 1 1 Positive Genetic
GET1 YGL020C Subunit of the GET complex genetic 1 1 1 Negative Genetic
EGD1 YPL037C Subunit beta1 of the nascent polypeptide-associated complex (NAC) genetic 1 1 1 Positive Genetic
DYN2 YDR424C Cytoplasmic light chain dynein, microtubule motor protein genetic 1 1 1 Positive Genetic
GDB1 YPR184W Glycogen debranching enzyme genetic 1 1 1 Positive Genetic
AIP1 YMR092C Actin cortical patch component genetic 1 1 1 Phenotypic Suppression
GPP2 YER062C DL-glycerol-3-phosphate phosphatase involved in glycerol biosynthesis genetic 1 1 1 Positive Genetic
CDC37 YDR168W Essential Hsp90p co-chaperone genetic 1 1 1 Positive Genetic
BEM3 YPL115C Rho GTPase activating protein (RhoGAP) physical 1 1 1 Two-hybrid
BEM3 YPL115C Rho GTPase activating protein (RhoGAP) genetic 1 1 1 Dosage Rescue
AIM46 YHR199C Protein of unknown function genetic 1 1 1 Negative Genetic
HHT1 YBR010W Histone H3 genetic 1 1 1 Positive Genetic
BOP2 YLR267W Protein of unknown function genetic 1 1 1 Positive Genetic
FPK1 YNR047W Ser/Thr protein kinase genetic 1 1 1 Synthetic Rescue
CIK1 YMR198W Kinesin-associated protein genetic 1 1 1 Positive Genetic
ECM33 YBR078W GPI-anchored protein involved in efficient glucose uptake genetic 1 1 1 Negative Genetic
EPT1 YHR123W sn-1,2-diacylglycerol ethanolamine- and cholinephosphotranferase genetic 1 1 1 Positive Genetic
CLB2 YPR119W B-type cyclin involved in cell cycle progression physical 1 1 1 Two-hybrid
CBR1 YIL043C Cytochrome b reductase and NADH-dependent reductase for Dph3p genetic 1 1 1 Negative Genetic
GCR2 YNL199C Transcriptional activator of genes involved in glycolysis physical 1 1 1 Two-hybrid
DAP1 YPL170W Heme-binding protein genetic 1 1 1 Positive Genetic
DUO1 YGL061C Essential subunit of the Dam1 complex (aka DASH complex) genetic 1 1 1 Positive Genetic
SHO1 YER118C Transmembrane osmosensor for filamentous growth and HOG pathways genetic 1 1 1 Synthetic Lethality
MYO3 YKL129C One of two type I myosins physical 1 1 1 Two-hybrid
MYO3 YKL129C One of two type I myosins genetic 1 1 1 Positive Genetic
RGD1 YBR260C GTPase-activating protein (RhoGAP) for Rho3p and Rho4p genetic 1 1 1 Dosage Rescue
SRN2 YLR119W Component of the ESCRT-I complex physical 1 1 1 Two-hybrid
HSL1 YKL101W Nim1p-related protein kinase physical 1 1 1 Two-hybrid
HSL1 YKL101W Nim1p-related protein kinase genetic 1 1 1 Positive Genetic
LSG1 YGL099W Putative GTPase involved in 60S ribosomal subunit biogenesis physical 1 1 1 Two-hybrid
MCM6 YGL201C Protein involved in DNA replication physical 1 1 1 Two-hybrid
MKK2 YPL140C MAPKK involved in the protein kinase C signaling pathway physical 1 1 1 Two-hybrid
MYO5 YMR109W One of two type I myosin motors physical 1 1 1 Two-hybrid
NIS1 YNL078W Protein involved in axial bud site selection physical 1 1 1 Two-hybrid
PFK1 YGR240C Alpha subunit of heterooctameric phosphofructokinase physical 1 1 1 Two-hybrid
ULS1 YOR191W Swi2/Snf2-related translocase, SUMO-Targeted Ubiquitin Ligase (STUbL) physical 1 1 1 Two-hybrid
RPL19B YBL027W Ribosomal 60S subunit protein L19B physical 1 1 1 Two-hybrid
SDH4 YDR178W Membrane anchor subunit of succinate dehydrogenase (SDH) physical 1 1 1 Two-hybrid
SPO71 YDR104C Meiosis-specific protein required for prospore membrane morphogenesis physical 1 1 1 Two-hybrid
STP22 YCL008C Component of the ESCRT-I complex physical 1 1 1 Two-hybrid
UBP7 YIL156W Ubiquitin-specific protease that cleaves ubiquitin-protein fusions physical 1 1 1 Two-hybrid
YBP2 YGL060W Central kinetochore associated protein physical 1 1 1 Two-hybrid
YOL036W YOL036W Protein of unknown function physical 1 1 1 Two-hybrid
KSS1 YGR040W Mitogen-activated protein kinase (MAPK) physical 1 1 1 PCA
MOB1 YIL106W Component of the mitotic exit network genetic 1 1 1 Synthetic Growth Defect
SHS1 YDL225W Component of the septin ring that is required for cytokinesis physical 1 1 1 PCA
SIZ1 YDR409W SUMO E3 ligase physical 1 1 1 Affinity Capture-MS
UBC9 YDL064W SUMO-conjugating enzyme involved in the Smt3p conjugation pathway physical 1 1 1 Affinity Capture-MS
IQG1 YPL242C Actin filament binding protein that enhances actin ring formation genetic 1 1 1 Dosage Rescue
MLC1 YGL106W Essential light chain for Myo1p physical 1 1 1 Reconstituted Complex
PUF3 YLL013C Protein of the mitochondrial outer surface physical 1 1 1 Affinity Capture-RNA
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
HRR25 YPL204W Conserved casein kinase, monopolin subunit physical 1 1 1 Affinity Capture-MS
SPA2 YLL021W Component of the polarisome genetic 1 1 1 Synthetic Lethality
KAR9 YPL269W Spindle positioning factor genetic 1 1 1 Synthetic Growth Defect
HSP104 YLL026W Disaggregase genetic 1 1 1 Synthetic Lethality
UPC2 YDR213W Sterol regulatory element binding protein genetic 1 1 1 Phenotypic Suppression
TOR1 YJR066W PIK-related protein kinase and rapamycin target genetic 1 1 1 Synthetic Growth Defect
TEM1 YML064C GTPase involved in initiation of Mitotic Exit Network (MEN) genetic 1 1 1 Synthetic Growth Defect
SWC3 YAL011W Protein of unknown function genetic 1 1 1 Positive Genetic
MYO4 YAL029C Type V myosin motor involved in actin-based transport of cargos genetic 1 1 1 Positive Genetic
URA7 YBL039C Major CTP synthase isozyme (see also URA8) genetic 1 1 1 Negative Genetic
IAI11 YBL059W Putative mitochondrial protein of unknown function genetic 1 1 1 Positive Genetic
KIP1 YBL063W Kinesin-related motor protein genetic 1 1 1 Positive Genetic
RPS8A YBL072C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
RKM3 YBR030W Ribosomal lysine methyltransferase genetic 1 1 1 Positive Genetic
UBC4 YBR082C Ubiquitin-conjugating enzyme (E2) genetic 1 1 1 Positive Genetic
YSA1 YBR111C Nudix hydrolase family member with ADP-ribose pyrophosphatase activity genetic 1 1 1 Negative Genetic
RAD16 YBR114W Nucleotide excision repair (NER) protein genetic 1 1 1 Negative Genetic
SHE3 YBR130C Protein adaptor between Myo4p and the She2p-mRNA complex genetic 1 1 1 Positive Genetic
TBS1 YBR150C Protein of unknown function genetic 1 1 1 Positive Genetic
SEC66 YBR171W Non-essential subunit of Sec63 complex genetic 1 1 1 Negative Genetic
SMY2 YBR172C GYF domain protein genetic 1 1 1 Positive Genetic
HPC2 YBR215W Subunit of the HIR complex genetic 1 1 1 Positive Genetic
SWC5 YBR231C Component of the SWR1 complex genetic 1 1 1 Positive Genetic
TRS20 YBR254C Core component of transport protein particle (TRAPP) complexes I-III genetic 1 1 1 Positive Genetic
MAL32 YBR299W Maltase (alpha-D-glucosidase) genetic 1 1 1 Positive Genetic
RER1 YCL001W Protein involved in retention of membrane proteins genetic 1 1 1 Positive Genetic
SGF29 YCL010C Component of the HAT/Core module of the SAGA, SLIK, and ADA complexes genetic 1 1 1 Negative Genetic
PDI1 YCL043C Protein disulfide isomerase genetic 1 1 1 Positive Genetic
MGR1 YCL044C Subunit of the mitochondrial (mt) i-AAA protease supercomplex genetic 1 1 1 Positive Genetic
PBN1 YCL052C Component of glycosylphosphatidylinositol-mannosyltransferase I genetic 1 1 1 Positive Genetic
POL4 YCR014C DNA polymerase IV genetic 1 1 1 Positive Genetic
MDH3 YDL078C Peroxisomal malate dehydrogenase genetic 1 1 1 Positive Genetic
NDE2 YDL085W Mitochondrial external NADH dehydrogenase genetic 1 1 1 Positive Genetic
PMT5 YDL093W Protein O-mannosyltransferase genetic 1 1 1 Positive Genetic
RRP42 YDL111C Exosome non-catalytic core component genetic 1 1 1 Positive Genetic
UFD2 YDL190C Ubiquitin (Ub) chain assembly factor (E4) genetic 1 1 1 Positive Genetic
SNF3 YDL194W Plasma membrane low glucose sensor, regulates glucose transport genetic 1 1 1 Positive Genetic
RTN2 YDL204W Reticulon protein genetic 1 1 1 Negative Genetic
PTP1 YDL230W Phosphotyrosine-specific protein phosphatase genetic 1 1 1 Positive Genetic
MRH1 YDR033W Protein that localizes primarily to the plasma membrane genetic 1 1 1 Negative Genetic
TPS2 YDR074W Phosphatase subunit of the trehalose-6-P synthase/phosphatase complex genetic 1 1 1 Negative Genetic
TVP15 YDR100W Integral membrane protein genetic 1 1 1 Positive Genetic
MTC5 YDR128W Subunit of SEACAT, a subcomplex of the SEA complex genetic 1 1 1 Positive Genetic
NUM1 YDR150W Protein required for nuclear migration genetic 1 1 1 Positive Genetic
SEC1 YDR164C Sm-like protein involved in docking and fusion of exocytic vesicles genetic 1 1 1 Positive Genetic
UBC1 YDR177W Ubiquitin-conjugating enzyme genetic 1 1 1 Positive Genetic
RTN1 YDR233C Reticulon protein genetic 1 1 1 Positive Genetic
SSD1 YDR293C Translational repressor genetic 1 1 1 Negative Genetic
SUR2 YDR297W Sphinganine C4-hydroxylase genetic 1 1 1 Positive Genetic
PMT7 YDR307W Putative protein mannosyltransferase similar to Pmt1p genetic 1 1 1 Negative Genetic
IPK1 YDR315C Inositol 1,3,4,5,6-pentakisphosphate 2-kinase genetic 1 1 1 Positive Genetic
SWA2 YDR320C Auxilin-like protein involved in vesicular transport genetic 1 1 1 Negative Genetic
SWR1 YDR334W Swi2/Snf2-related ATPase genetic 1 1 1 Positive Genetic
YPS7 YDR349C Putative GPI-anchored aspartic protease genetic 1 1 1 Positive Genetic
SHE9 YDR393W Protein required for normal mitochondrial morphology genetic 1 1 1 Positive Genetic
RPB7 YDR404C RNA polymerase II subunit B16 genetic 1 1 1 Positive Genetic
LRS4 YDR439W Nucleolar protein that forms a complex with Csm1p genetic 1 1 1 Positive Genetic
PAC11 YDR488C Dynein intermediate chain, microtubule motor protein genetic 1 1 1 Positive Genetic
SDH7 YDR511W Mitochondrial protein involved in assembly of succinate dehydrogenase genetic 1 1 1 Positive Genetic
VAC8 YEL013W Vacuole-specific Myo2p receptor genetic 1 1 1 Negative Genetic
RIP1 YEL024W Ubiquinol-cytochrome-c reductase genetic 1 1 1 Positive Genetic
RAD23 YEL037C Protein with ubiquitin-like N terminus genetic 1 1 1 Positive Genetic
YPT31 YER031C Rab family GTPase genetic 1 1 1 Negative Genetic
IES5 YER092W Non-essential INO80 chromatin remodeling complex subunit genetic 1 1 1 Positive Genetic
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p) genetic 1 1 1 Negative Genetic
YCK3 YER123W Palmitoylated vacuolar membrane-localized casein kinase I isoform genetic 1 1 1 Negative Genetic
SWP82 YFL049W Member of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Negative Genetic
MIC19 YFR011C Component of the MICOS complex genetic 1 1 1 Positive Genetic
PRE4 YFR050C Beta 7 subunit of the 20S proteasome genetic 1 1 1 Positive Genetic
MPO1 YGL010W Dioxygenase that catalyzes alpha-oxygenation of 2-hydroxy fatty acids genetic 1 1 1 Positive Genetic
PMR1 YGL167C High affinity Ca2+/Mn2+ P-type ATPase genetic 1 1 1 Negative Genetic
POX1 YGL205W Fatty-acyl coenzyme A oxidase genetic 1 1 1 Negative Genetic
SHE10 YGL228W Protein involved in outer spore wall assembly genetic 1 1 1 Positive Genetic
MTO1 YGL236C Mitochondrial protein genetic 1 1 1 Positive Genetic
POP6 YGR030C Subunit of RNase MRP, nuclear RNase P and telomerase genetic 1 1 1 Positive Genetic
PEF1 YGR058W Penta-EF-hand protein genetic 1 1 1 Positive Genetic
UPF3 YGR072W Component of the nonsense-mediated mRNA decay (NMD) pathway genetic 1 1 1 Positive Genetic
SMD1 YGR074W Core Sm protein Sm D1 genetic 1 1 1 Positive Genetic
PAC10 YGR078C Part of the heteromeric co-chaperone GimC/prefoldin complex genetic 1 1 1 Positive Genetic
NNF2 YGR089W Protein that exhibits physical and genetic interactions with Rpb8p genetic 1 1 1 Positive Genetic
RPS23A YGR118W Ribosomal protein 28 (rp28) of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
PHB1 YGR132C Subunit of the prohibitin complex (Phb1p-Phb2p) genetic 1 1 1 Positive Genetic
TIF4631 YGR162W Translation initiation factor eIF4G and scaffold protein genetic 1 1 1 Positive Genetic
PBP1 YGR178C Component of glucose deprivation induced stress granules genetic 1 1 1 Negative Genetic
SOL4 YGR248W 6-phosphogluconolactonase genetic 1 1 1 Positive Genetic
VMR1 YHL035C Vacuolar membrane protein genetic 1 1 1 Positive Genetic
YHR045W YHR045W Putative protein of unknown function genetic 1 1 1 Positive Genetic
YPT35 YHR105W Endosomal protein of unknown function genetic 1 1 1 Positive Genetic
UBA4 YHR111W E1-like protein that activates Urm1p before urmylation genetic 1 1 1 Positive Genetic
YCK1 YHR135C Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform genetic 1 1 1 Negative Genetic
NVJ1 YHR195W Nuclear envelope protein genetic 1 1 1 Negative Genetic
TED1 YIL039W GPI-glycan remodelase genetic 1 1 1 Positive Genetic
PKP1 YIL042C Mitochondrial protein kinase genetic 1 1 1 Positive Genetic
RCI37 YIL077C Protein that associates with the large mitoribosomal subunit genetic 1 1 1 Positive Genetic
ICE2 YIL090W Integral ER membrane protein with type-III transmembrane domains genetic 1 1 1 Positive Genetic
KAR2 YJL034W ATPase involved in protein import into the ER genetic 1 1 1 Positive Genetic
LAS21 YJL062W Mannose-ethanolamine phosphotransferase genetic 1 1 1 Negative Genetic
PRY3 YJL078C GPI-anchored cell wall protein involved in export of sterols genetic 1 1 1 Positive Genetic
SIP4 YJL089W C6 zinc cluster transcriptional activator genetic 1 1 1 Positive Genetic
SAP185 YJL098W Protein that forms a complex with the Sit4p protein phosphatase genetic 1 1 1 Positive Genetic
LSM1 YJL124C Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
LCB3 YJL134W Long-chain base-1-phosphate phosphatase genetic 1 1 1 Negative Genetic
YUR1 YJL139C Mannosyltransferase involved in protein N-glycosylation genetic 1 1 1 Positive Genetic
SFH5 YJL145W Unusual phosphatidylinositol transfer protein (PITP) that binds heme genetic 1 1 1 Positive Genetic
RPA34 YJL148W RNA polymerase I subunit A34.5 genetic 1 1 1 Positive Genetic
INO1 YJL153C Inositol-3-phosphate synthase genetic 1 1 1 Positive Genetic
TPK1 YJL164C cAMP-dependent protein kinase catalytic subunit genetic 1 1 1 Positive Genetic
SET2 YJL168C Histone methyltransferase with a role in transcriptional elongation genetic 1 1 1 Positive Genetic
PHO90 YJL198W Low-affinity phosphate transporter genetic 1 1 1 Positive Genetic
NUC1 YJL208C Major mitochondrial nuclease genetic 1 1 1 Positive Genetic
PTK2 YJR059W Serine/threonine protein kinase genetic 1 1 1 Positive Genetic
YJR084W YJR084W Protein that forms a complex with Thp3p genetic 1 1 1 Positive Genetic
TMA19 YKL056C Protein that associates with ribosomes genetic 1 1 1 Positive Genetic
SMY1 YKL079W Kinesin-like myosin passenger-protein genetic 1 1 1 Negative Genetic
KTI12 YKL110C Protein that plays a role in modification of tRNA wobble nucleosides genetic 1 1 1 Negative Genetic
IRS4 YKR019C EH domain-containing protein genetic 1 1 1 Positive Genetic
SET3 YKR029C Defining member of the SET3 histone deacetylase complex genetic 1 1 1 Positive Genetic
SHB17 YKR043C Sedoheptulose bisphosphatase involved in riboneogenesis genetic 1 1 1 Positive Genetic
LAS1 YKR063C Endonuclease involved in pre-rRNA processing at both ends of ITS2 genetic 1 1 1 Positive Genetic
PAM17 YKR065C Constituent of the TIM23 complex genetic 1 1 1 Positive Genetic
MLP1 YKR095W Myosin-like protein associated with the nuclear envelope genetic 1 1 1 Positive Genetic
NFT1 YKR103W Putative transporter of the MRP subfamily genetic 1 1 1 Positive Genetic
YCT1 YLL055W High-affinity cysteine-specific transporter genetic 1 1 1 Positive Genetic
SPT8 YLR055C Subunit of the SAGA transcriptional regulatory complex genetic 1 1 1 Positive Genetic
SHM2 YLR058C Cytosolic serine hydroxymethyltransferase genetic 1 1 1 Positive Genetic
YEF3 YLR249W Translation elongation factor 3 genetic 1 1 1 Positive Genetic
RPS28B YLR264W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
SEC22 YLR268W R-SNARE protein genetic 1 1 1 Positive Genetic
YLR287C YLR287C Putative protein of unknown function genetic 1 1 1 Positive Genetic
VIP1 YLR410W Bifunctional inositol pyrophosphate kinase and phosphatase genetic 1 1 1 Negative Genetic
SEN1 YLR430W ATP-dependent 5' to 3' RNA/DNA and DNA helicase genetic 1 1 1 Positive Genetic
USA1 YML029W Scaffold subunit of the Hrd1p ubiquitin ligase genetic 1 1 1 Positive Genetic
YMD8 YML038C Putative nucleotide sugar transporter genetic 1 1 1 Positive Genetic
SUR7 YML052W Plasma membrane protein, component of eisosomes genetic 1 1 1 Negative Genetic
MFT1 YML062C Subunit of the THO complex genetic 1 1 1 Positive Genetic
TCB3 YML072C Cortical ER protein involved in ER-plasma membrane tethering genetic 1 1 1 Negative Genetic
PHO84 YML123C High-affinity inorganic phosphate (Pi) transporter genetic 1 1 1 Positive Genetic
MSC1 YML128C Protein of unknown function genetic 1 1 1 Positive Genetic
MUB1 YMR100W MYND domain-containing protein genetic 1 1 1 Negative Genetic
NDE1 YMR145C Mitochondrial external NADH dehydrogenase genetic 1 1 1 Positive Genetic
RIM13 YMR154C Calpain-like cysteine protease genetic 1 1 1 Positive Genetic
MSS11 YMR164C Transcription factor genetic 1 1 1 Positive Genetic
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family genetic 1 1 1 Negative Genetic
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 1 1 1 Positive Genetic
UBP8 YMR223W Ubiquitin-specific protease component of the SAGA acetylation complex genetic 1 1 1 Positive Genetic
HOR7 YMR251W-A Protein of unknown function genetic 1 1 1 Positive Genetic
LIP1 YMR298W Ceramide synthase subunit genetic 1 1 1 Negative Genetic
TGL3 YMR313C Bifunctional triacylglycerol lipase and LPE acyltransferase genetic 1 1 1 Positive Genetic
LAP2 YNL045W Leucyl aminopeptidase yscIV with epoxide hydrolase activity genetic 1 1 1 Negative Genetic
YNL046W YNL046W Putative protein of unknown function genetic 1 1 1 Positive Genetic
TOM7 YNL070W Component of the TOM (translocase of outer membrane) complex genetic 1 1 1 Negative Genetic
TPM1 YNL079C Major isoform of tropomyosin genetic 1 1 1 Negative Genetic
PHO23 YNL097C Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Positive Genetic
OCA1 YNL099C Putative protein tyrosine phosphatase genetic 1 1 1 Positive Genetic
TOM22 YNL131W Component of the TOM (Translocase of Outer Membrane) complex genetic 1 1 1 Positive Genetic
YNL146W YNL146W Putative protein of unknown function genetic 1 1 1 Positive Genetic
YCK2 YNL154C Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform genetic 1 1 1 Negative Genetic
IES2 YNL215W Protein that associates with the INO80 chromatin remodeling complex genetic 1 1 1 Positive Genetic
ZWF1 YNL241C Glucose-6-phosphate dehydrogenase (G6PD) genetic 1 1 1 Negative Genetic
TOS6 YNL300W Glycosylphosphatidylinositol-dependent cell wall protein genetic 1 1 1 Positive Genetic
MCK1 YNL307C Dual-specificity ser/thr and tyrosine protein kinase genetic 1 1 1 Negative Genetic
VPS27 YNR006W Endosomal protein that forms a complex with Hse1p genetic 1 1 1 Positive Genetic
LRO1 YNR008W Acyltransferase that converts diacylglycerol to triacylglycerol (TGA) genetic 1 1 1 Positive Genetic
PHO91 YNR013C Low-affinity vacuolar phosphate transporter genetic 1 1 1 Positive Genetic
YNR021W YNR021W Putative protein of unknown function genetic 1 1 1 Positive Genetic
MVD1 YNR043W Mevalonate pyrophosphate decarboxylase genetic 1 1 1 Positive Genetic
PDR18 YNR070W Transporter of the ATP-binding cassette (ABC) family genetic 1 1 1 Negative Genetic
PLB3 YOL011W Phospholipase B (lysophospholipase) involved in lipid metabolism genetic 1 1 1 Positive Genetic
PSK2 YOL045W PAS-domain containing serine/threonine protein kinase genetic 1 1 1 Negative Genetic
INP54 YOL065C Phosphatidylinositol 4,5-bisphosphate 5-phosphatase genetic 1 1 1 Positive Genetic
ITR2 YOL103W Myo-inositol transporter genetic 1 1 1 Positive Genetic
SHR5 YOL110W Palmitoyltransferase subunit genetic 1 1 1 Positive Genetic
MDY2 YOL111C Protein involved in inserting tail-anchored proteins into ER membranes genetic 1 1 1 Positive Genetic
SGT2 YOR007C Glutamine-rich cytoplasmic cochaperone genetic 1 1 1 Negative Genetic
SLG1 YOR008C Sensor-transducer of the stress-activated PKC1-MPK1 kinase pathway genetic 1 1 1 Negative Genetic
RAS1 YOR101W GTPase involved in G-protein signaling in adenylate cyclase activation genetic 1 1 1 Positive Genetic
LIP5 YOR196C Protein involved in biosynthesis of the coenzyme lipoic acid genetic 1 1 1 Positive Genetic
LDB19 YOR322C Alpha-arrestin, Ub-ligase adaptor for Rsp5p genetic 1 1 1 Positive Genetic
MYO2 YOR326W Type V myosin motor involved in actin-based transport of cargos genetic 1 1 1 Positive Genetic
PDE2 YOR360C High-affinity cyclic AMP phosphodiesterase genetic 1 1 1 Negative Genetic
PMA2 YPL036W Plasma membrane H+-ATPase genetic 1 1 1 Positive Genetic
YDC1 YPL087W Alkaline dihydroceramidase, involved in sphingolipid metabolism genetic 1 1 1 Positive Genetic
PNG1 YPL096W Conserved peptide N-glycanase genetic 1 1 1 Negative Genetic
PXA1 YPL147W Subunit of heterodimeric peroxisomal ABC transport complex, with Pxa2p genetic 1 1 1 Positive Genetic
TGS1 YPL157W Trimethyl guanosine synthase, conserved nucleolar methyl transferase genetic 1 1 1 Positive Genetic
PPQ1 YPL179W Protein phosphatase that regulates the mating response genetic 1 1 1 Positive Genetic
LEA1 YPL213W Component of U2 snRNP complex genetic 1 1 1 Positive Genetic
NEW1 YPL226W Translation termination and ribosome biogenesis factor genetic 1 1 1 Positive Genetic
SAM3 YPL274W High-affinity S-adenosylmethionine permease genetic 1 1 1 Positive Genetic
YOP1 YPR028W Reticulon-interacting protein genetic 1 1 1 Positive Genetic
YMC1 YPR058W Secondary mitochondrial inner membrane glycine transporter genetic 1 1 1 Positive Genetic
MED1 YPR070W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Positive Genetic
YPR071W YPR071W Putative membrane protein genetic 1 1 1 Negative Genetic
RHO1 YPR165W GTP-binding protein of the rho subfamily of Ras-like proteins genetic 1 1 1 Dosage Rescue
RHO2 YNL090W Non-essential small GTPase of the Rho/Rac family of Ras-like proteins genetic 1 1 1 Dosage Rescue
MSS4 YDR208W Phosphatidylinositol-4-phosphate 5-kinase genetic 1 1 1 Dosage Rescue
KDX1 YKL161C Protein kinase genetic 1 1 1 Dosage Rescue
RGD2 YFL047W GTPase-activating protein (RhoGAP) for Cdc42p and Rho5p genetic 1 1 1 Dosage Rescue
SAC7 YDR389W GTPase activating protein (GAP) for Rho1p genetic 1 1 1 Synthetic Rescue
LRG1 YDL240W GTPase-activating protein (GAP) genetic 1 1 1 Synthetic Rescue
PXL1 YKR090W Protein that localizes to sites of polarized growth genetic 1 1 1 Synthetic Rescue
NAB6 YML117W Putative RNA-binding protein genetic 1 1 1 Dosage Rescue
TUS1 YLR425W Guanine nucleotide exchange factor (GEF) that modulates Rho1p activity genetic 1 1 1 Dosage Rescue
ROM1 YGR070W Guanine nucleotide exchange factor (GEF) for Rho1p genetic 1 1 1 Dosage Rescue
RGA1 YOR127W GTPase-activating protein for polarity-regulator Cdc42p (RhoGAP) genetic 1 1 1 Dosage Rescue
VHS2 YIL135C Regulator of septin dynamics genetic 1 1 1 Dosage Rescue
KIN82 YCR091W Putative serine/threonine protein kinase genetic 1 1 1 Synthetic Rescue
ARP1 YHR129C Actin-related protein of the dynactin complex genetic 1 1 1 Positive Genetic
BIL2 YGL015C Formin inhibitor genetic 1 1 1 Synthetic Lethality
BNI4 YNL233W Targeting subunit for Glc7p protein phosphatase genetic 1 1 1 Positive Genetic
ALY2 YJL084C Alpha arrestin, Ub-ligase adaptor for Rsp5p physical 1 1 1 Two-hybrid
AIM3 YBR108W Protein that inhibits barbed-end actin filament elongation physical 1 1 1 Two-hybrid
ECI1 YLR284C Peroxisomal delta3,delta2-enoyl-CoA isomerase genetic 1 1 1 Negative Genetic
DSE3 YOR264W Daughter cell-specific protein, may help establish daughter fate physical 1 1 1 Two-hybrid
BOS1 YLR078C v-SNARE (vesicle specific SNAP receptor) genetic 1 1 1 Positive Genetic
ELP3 YPL086C Subunit of Elongator complex genetic 1 1 1 Positive Genetic
GIP3 YPL137C Cytoplasmic protein that regulates protein phosphatase 1 Glc7p genetic 1 1 1 Negative Genetic
CBF1 YJR060W Basic helix-loop-helix (bHLH) protein genetic 1 1 1 Negative Genetic
BUD4 YJR092W Anillin-like protein involved in bud-site selection physical 1 1 1 Two-hybrid
EPS1 YIL005W ER protein with chaperone and co-chaperone activity genetic 1 1 1 Positive Genetic
BNI5 YNL166C Linker protein responsible for recruitment of myosin to the bud neck genetic 1 1 1 Synthetic Lethality
CIN1 YOR349W Tubulin folding factor D involved in beta-tubulin (Tub2p) folding genetic 1 1 1 Positive Genetic
BNR1 YIL159W Formin genetic 1 1 1 Phenotypic Suppression
GIC1 YHR061C Rho-family GTPase interacting protein and Cdc42p effector physical 1 1 1 Two-hybrid
BUD6 YLR319C Actin- and formin-interacting protein genetic 1 1 1 Synthetic Rescue
DAL80 YKR034W Negative regulator of genes in multiple nitrogen degradation pathways genetic 1 1 1 Negative Genetic
HFA1 YMR207C Mitochondrial acetyl-coenzyme A carboxylase genetic 1 1 1 Positive Genetic
HMT1 YBR034C Nuclear SAM-dependent mono- and asymmetric methyltransferase physical 1 1 1 Affinity Capture-MS
FIR1 YER032W Protein involved in 3' mRNA processing physical 1 1 1 Two-hybrid
CLA4 YNL298W Cdc42p-activated signal transducing kinase genetic 1 1 1 Negative Genetic
GTT1 YIR038C ER associated glutathione S-transferase genetic 1 1 1 Positive Genetic
ALG5 YPL227C UDP-glucose:dolichyl-phosphate glucosyltransferase genetic 1 1 1 Positive Genetic
CQD1 YPL109C UbiB family mitochondrial protein genetic 1 1 1 Negative Genetic
HHT2 YNL031C Histone H3 genetic 1 1 1 Positive Genetic
AUR1 YKL004W Phosphatidylinositol:ceramide phosphoinositol transferase genetic 1 1 1 Negative Genetic
ERV29 YGR284C Protein localized to COPII-coated vesicles genetic 1 1 1 Positive Genetic
CYB2 YML054C Cytochrome b2 (L-lactate cytochrome-c oxidoreductase) genetic 1 1 1 Positive Genetic
HAC1 YFL031W Basic leucine zipper (bZIP) transcription factor (ATF/CREB1 homolog) genetic 1 1 1 Positive Genetic
ARL3 YPL051W ARF-like small GTPase of the RAS superfamily genetic 1 1 1 Positive Genetic
ERF2 YLR246W Subunit of a palmitoyltransferase genetic 1 1 1 Positive Genetic
ERV14 YGL054C COPII-coated vesicle protein genetic 1 1 1 Positive Genetic
FAF1 YIL019W Protein required for pre-rRNA processing genetic 1 1 1 Positive Genetic
DPM1 YPR183W Dolichol phosphate mannose (Dol-P-Man) synthase of ER membrane genetic 1 1 1 Positive Genetic
AIM44 YPL158C Regulator of Cdc42p and Rho1p genetic 1 1 1 Synthetic Lethality
BUG1 YDL099W Cis-golgi localized protein involved in ER to Golgi transport genetic 1 1 1 Positive Genetic
HMG1 YML075C HMG-CoA reductase genetic 1 1 1 Positive Genetic
ATF1 YOR377W Alcohol acetyltransferase genetic 1 1 1 Positive Genetic
EGT2 YNL327W Glycosylphosphatidylinositol (GPI)-anchored cell wall endoglucanase genetic 1 1 1 Synthetic Rescue
GAS5 YOL030W 1,3-beta-glucanosyltransferase genetic 1 1 1 Positive Genetic
FAT1 YBR041W Very long chain fatty acyl-CoA synthetase and fatty acid transporter genetic 1 1 1 Positive Genetic
ACB1 YGR037C Acyl-CoA-binding protein genetic 1 1 1 Positive Genetic
ELF1 YKL160W Transcription elongation factor with a conserved zinc finger domain genetic 1 1 1 Positive Genetic
CAJ1 YER048C Nuclear type II J heat shock protein of the E. coli dnaJ family genetic 1 1 1 Positive Genetic
CWH41 YGL027C Processing alpha glucosidase I genetic 1 1 1 Positive Genetic
ATF2 YGR177C Alcohol acetyltransferase genetic 1 1 1 Negative Genetic
ALT1 YLR089C Alanine transaminase (glutamic pyruvic transaminase) genetic 1 1 1 Positive Genetic
GAA1 YLR088W Subunit of the GPI:protein transamidase complex genetic 1 1 1 Positive Genetic
ACL4 YDR161W Specific assembly chaperone for ribosomal protein Rpl4a/Rpl4b genetic 1 1 1 Positive Genetic
DEG1 YFL001W tRNA:pseudouridine synthase genetic 1 1 1 Negative Genetic
CYC3 YAL039C Cytochrome c heme lyase (holocytochrome c synthase) genetic 1 1 1 Negative Genetic
EMC4 YGL231C Member of conserved ER transmembrane complex genetic 1 1 1 Positive Genetic
GIS1 YDR096W Histone demethylase and transcription factor genetic 1 1 1 Negative Genetic
ALG7 YBR243C UDP-N-acetyl-glucosamine-1-P transferase genetic 1 1 1 Positive Genetic
HLJ1 YMR161W Co-chaperone for Hsp40p genetic 1 1 1 Positive Genetic
ERP6 YGL002W Member of the p24 family involved in ER to Golgi transport genetic 1 1 1 Positive Genetic
ERG3 YLR056W C-5 sterol desaturase genetic 1 1 1 Positive Genetic
COS10 YNR075W Endosomal protein involved in turnover of plasma membrane proteins genetic 1 1 1 Positive Genetic
DSE2 YHR143W Daughter cell-specific secreted protein with similarity to glucanases genetic 1 1 1 Synthetic Rescue
CTS1 YLR286C Endochitinase genetic 1 1 1 Synthetic Rescue
AFT2 YPL202C Iron-regulated transcriptional activator genetic 1 1 1 Positive Genetic
DNF3 YMR162C Trans-golgi network aminophospholipid translocase (flippase) physical 1 1 1 Two-hybrid
ERD1 YDR414C Predicted membrane protein required for lumenal ER protein retention genetic 1 1 1 Negative Genetic
COX8 YLR395C Subunit VIII of cytochrome c oxidase (Complex IV) genetic 1 1 1 Positive Genetic
FMC1 YIL098C Mitochondrial matrix protein genetic 1 1 1 Positive Genetic
ERG8 YMR220W Phosphomevalonate kinase genetic 1 1 1 Positive Genetic
FEN2 YCR028C Plasma membrane H+-pantothenate symporter genetic 1 1 1 Positive Genetic
ECT1 YGR007W Ethanolamine-phosphate cytidylyltransferase genetic 1 1 1 Negative Genetic
CBT1 YKL208W Protein involved in 5' RNA end processing genetic 1 1 1 Positive Genetic
AIM36 YMR157C Protein of unknown function genetic 1 1 1 Positive Genetic
APQ12 YIL040W Nuclear envelope/ER integral membrane protein genetic 1 1 1 Positive Genetic
FAT3 YKL187C Protein required for fatty acid uptake genetic 1 1 1 Positive Genetic
CAX4 YGR036C Dolichyl pyrophosphate (Dol-P-P) phosphatase genetic 1 1 1 Positive Genetic