Standard name Systematic name Name description Description
MIC27 YNL100W Component of the MICOS complex Component of the MICOS complex; MICOS (formerly MINOS or MitOS), a mitochondrial inner membrane complex that extends into the intermembrane space with a role in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane; forms a subcomplex with Mic10p and Mic12p whose assembly and stability requires cardiolipin; orthologous to human APOO and APOOL
Visualize the interactome of MIC27
Links to external databases:
SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Mito 0.908 0.943 0.825
Nuc Periphery 0.102 NaN NaN
Nucleolus 0.087 NaN NaN
Vac/Vac Memb 0.107 0.055 NaN
Endosome NaN NaN 0.064
Golgi NaN NaN 0.205
Peroxisome NaN NaN 0.070

GFP localization & abundance

GFP localization GFP abundance
no data no data

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
MIC27 0 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
MIC60 YKR016W Component of the MICOS complex physical 9 3 6 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Co-purification, Co-purification, Affinity Capture-Western, Affinity Capture-Western
MIC10 YCL057C-A Conserved component of the MICOS complex physical 6 2 4 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western
MIC26 YGR235C Component of the MICOS complex physical 5 3 3 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Co-purification
MIC12 YBR262C Component of the MICOS complex physical 5 2 3 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western
MIC19 YFR011C Component of the MICOS complex physical 4 2 2 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS
FKH1 YIL131C Forkhead family transcription factor regulation 3 2 3 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation- exonuclease evidence, chromatin immunoprecipitation-chip evidence
CRD1 YDL142C Cardiolipin synthase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
AFG3 YER017C Mitochondrial inner membrane m-AAA protease component genetic 2 1 2 Negative Genetic, Negative Genetic
MGR1 YCL044C Subunit of the mitochondrial (mt) i-AAA protease supercomplex genetic 2 1 2 Negative Genetic, Negative Genetic
UBC7 YMR022W Ubiquitin conjugating enzyme genetic 2 1 2 Negative Genetic, Negative Genetic
PTK2 YJR059W Serine/threonine protein kinase genetic 2 1 2 Negative Genetic, Negative Genetic
HOF1 YMR032W F-BAR protein that regulates actin cytoskeleton organization genetic 2 1 1 Positive Genetic, Positive Genetic
MDM34 YGL219C Mitochondrial component of the ERMES complex genetic 2 1 1 Negative Genetic, Negative Genetic
HER2 YMR293C Subunit of the trimeric GatFAB AmidoTransferase(AdT) complex genetic 2 1 1 Negative Genetic, Negative Genetic
YTA12 YMR089C Mitochondrial inner membrane m-AAA protease component genetic 2 1 1 Negative Genetic, Negative Genetic
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes genetic 2 1 1 Dosage Lethality, Dosage Lethality
SHE9 YDR393W Protein required for normal mitochondrial morphology genetic 2 1 1 Negative Genetic, Negative Genetic
BUR6 YER159C Subunit of a heterodimeric NC2 transcription regulator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ADR1 YDR216W Carbon source-responsive zinc-finger transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
IPI1 YHR085W Component of the Rix1 complex and possibly pre-replicative complexes genetic 1 1 1 Negative Genetic
HCA4 YJL033W DEAD box RNA helicase genetic 1 1 1 Negative Genetic
CFT2 YLR115W Subunit of the mRNA cleavage and polyadenlylation factor (CPF) genetic 1 1 1 Positive Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
ARP3 YJR065C Essential component of the Arp2/3 complex genetic 1 1 1 Positive Genetic
COX4 YGL187C Subunit IV of cytochrome c oxidase physical 1 1 1 Affinity Capture-MS
FKS1 YLR342W Catalytic subunit of 1,3-beta-D-glucan synthase genetic 1 1 1 Negative Genetic
ISW2 YOR304W ATP-dependent DNA translocase involved in chromatin remodeling genetic 1 1 1 Negative Genetic
HOS2 YGL194C Histone deacetylase and subunit of Set3 and Rpd3L complexes genetic 1 1 1 Negative Genetic
GLN1 YPR035W Glutamine synthetase (GS) genetic 1 1 1 Negative Genetic
ACE2 YLR131C Transcription factor required for septum destruction after cytokinesis genetic 1 1 1 Negative Genetic
CYM1 YDR430C Lysine-specific metalloprotease of the pitrilysin family genetic 1 1 1 Negative Genetic
DNM1 YLL001W Dynamin-related GTPase involved in mitochondrial organization genetic 1 1 1 Negative Genetic
AXL1 YPR122W Haploid specific endoprotease of a-factor mating pheromone genetic 1 1 1 Positive Genetic
LAS1 YKR063C Endonuclease involved in pre-rRNA processing at both ends of ITS2 genetic 1 1 1 Negative Genetic
BCK2 YER167W Serine/threonine-rich protein involved in PKC1 signaling pathway genetic 1 1 1 Positive Genetic
LSC1 YOR142W Alpha subunit of succinyl-CoA ligase genetic 1 1 1 Negative Genetic
HAP3 YBL021C Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex genetic 1 1 1 Negative Genetic
EAP1 YKL204W eIF4E-associated protein, competes with eIF4G for binding to eIF4E genetic 1 1 1 Positive Genetic
MEH1 YKR007W Subunit of the EGO/GSE complex genetic 1 1 1 Negative Genetic
MIC19 YFR011C Component of the MICOS complex genetic 1 1 1 Negative Genetic
ALD5 YER073W Mitochondrial aldehyde dehydrogenase genetic 1 1 1 Positive Genetic
BIR1 YJR089W Subunit of chromosomal passenger complex (CPC) genetic 1 1 1 Negative Genetic
IME2 YJL106W Serine/threonine protein kinase involved in activation of meiosis genetic 1 1 1 Negative Genetic
BIL2 YGL015C Formin inhibitor genetic 1 1 1 Negative Genetic
GEP4 YHR100C Mitochondrial phosphatidylglycerophosphatase (PGP phosphatase) genetic 1 1 1 Negative Genetic
AIM7 YDR063W Protein that interacts with Arp2/3 complex genetic 1 1 1 Negative Genetic
FIS1 YIL065C Protein involved in mitochondrial fission and peroxisome abundance genetic 1 1 1 Negative Genetic
GMH1 YKR030W Golgi membrane protein of unknown function genetic 1 1 1 Negative Genetic
CRP1 YHR146W Protein that binds to cruciform DNA structures genetic 1 1 1 Negative Genetic
IMP1 YMR150C Catalytic subunit of mitochondrial inner membrane peptidase complex genetic 1 1 1 Negative Genetic
EMP47 YFL048C Integral membrane component of ER-derived COPII-coated vesicles genetic 1 1 1 Positive Genetic
HAP4 YKL109W Transcription factor genetic 1 1 1 Negative Genetic
GAP1 YKR039W General amino acid permease genetic 1 1 1 Negative Genetic
ABF1 YKL112W DNA binding protein with possible chromatin-reorganizing activity genetic 1 1 1 Negative Genetic
MET32 YDR253C Zinc-finger DNA-binding transcription factor genetic 1 1 1 Negative Genetic
ECM27 YJR106W Protein involved in calcium homeostasis and exit from quiescence genetic 1 1 1 Negative Genetic
FRK1 YPL141C Protein kinase of unknown cellular role genetic 1 1 1 Negative Genetic
DAL5 YJR152W Allantoate permease genetic 1 1 1 Negative Genetic
BNA7 YDR428C Formylkynurenine formamidase genetic 1 1 1 Positive Genetic
MBA1 YBR185C Membrane-associated mitochondrial ribosome receptor genetic 1 1 1 Positive Genetic
MEF2 YJL102W Mitochondrial elongation factor involved in translational elongation genetic 1 1 1 Negative Genetic
CAJ1 YER048C Nuclear type II J heat shock protein of the E. coli dnaJ family genetic 1 1 1 Negative Genetic
GEM1 YAL048C Outer mitochondrial membrane GTPase, subunit of the ERMES complex genetic 1 1 1 Negative Genetic
IDI1 YPL117C Isopentenyl diphosphate:dimethylallyl diphosphate isomerase genetic 1 1 1 Negative Genetic
AIM11 YER093C-A Protein of unknown function genetic 1 1 1 Negative Genetic
AGE1 YDR524C ADP-ribosylation factor (ARF) GTPase activating protein (GAP) effector genetic 1 1 1 Negative Genetic
MET8 YBR213W Bifunctional dehydrogenase and ferrochelatase genetic 1 1 1 Negative Genetic
CMC1 YKL137W Copper-binding protein of the mitochondrial intermembrane space genetic 1 1 1 Negative Genetic
FAU1 YER183C 5,10-methenyltetrahydrofolate synthetase genetic 1 1 1 Negative Genetic
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
SAM50 YNL026W Component of the Sorting and Assembly Machinery (SAM) complex physical 1 1 1 Affinity Capture-Western
TIM23 YNR017W Essential component of the TIM23 complex physical 1 1 1 Affinity Capture-MS
NRD1 YNL251C RNA-binding subunit of Nrd1 complex genetic 1 1 1 Synthetic Growth Defect
REB1 YBR049C RNA polymerase I enhancer binding protein genetic 1 1 1 Positive Genetic
TIF34 YMR146C eIF3i subunit of the eukaryotic translation initiation factor 3 (eIF3) genetic 1 1 1 Positive Genetic
YMR155W YMR155W Putative protein of unknown function genetic 1 1 1 Positive Genetic
VPS8 YAL002W Membrane-binding component of the CORVET complex genetic 1 1 1 Positive Genetic
NUP170 YBL079W Subunit of inner ring of nuclear pore complex (NPC) genetic 1 1 1 Positive Genetic
RAD57 YDR004W Protein that stimulates strand exchange genetic 1 1 1 Positive Genetic
PAD1 YDR538W Phenylacrylic acid decarboxylase genetic 1 1 1 Positive Genetic
MXR1 YER042W Methionine-S-sulfoxide reductase genetic 1 1 1 Positive Genetic
YER137C YER137C Protein of unknown function genetic 1 1 1 Positive Genetic
QCR9 YGR183C Subunit 9 of ubiquinol cytochrome-c reductase (Complex III) genetic 1 1 1 Positive Genetic
YHL008C YHL008C Putative protein of unknown function genetic 1 1 1 Positive Genetic
TIM22 YDL217C Essential core component of mitochondrial TIM22 complex genetic 1 1 1 Negative Genetic
MOB2 YFL034C-B Activator of Cbk1p kinase genetic 1 1 1 Negative Genetic
YIP1 YGR172C Integral membrane protein genetic 1 1 1 Negative Genetic
NOP19 YGR251W Ribosome biogenesis factor genetic 1 1 1 Negative Genetic
SOG2 YOR353C Key component of the RAM signaling network genetic 1 1 1 Negative Genetic
TAH18 YPR048W Conserved NAPDH-dependent diflavin reductase genetic 1 1 1 Negative Genetic
MRX14 YDR115W Putative mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
SOM1 YEL059C-A Subunit of the mitochondrial inner membrane peptidase (IMP) genetic 1 1 1 Negative Genetic
TIM21 YGR033C Nonessential component of the TIM23 complex genetic 1 1 1 Negative Genetic
PET130 YJL023C Protein of unknown function genetic 1 1 1 Negative Genetic
TRK1 YJL129C Component of the Trk1p-Trk2p potassium transport system genetic 1 1 1 Negative Genetic
MMM1 YLL006W ER integral membrane protein, ERMES complex subunit genetic 1 1 1 Negative Genetic
YLL066W-B YLL066W-B Putative protein of unknown function genetic 1 1 1 Negative Genetic
MRPL24 YMR193W Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
SCS22 YBL091C-A Protein involved in regulation of phospholipid metabolism genetic 1 1 1 Negative Genetic
NTH2 YBR001C Putative neutral trehalase, required for thermotolerance genetic 1 1 1 Negative Genetic
RPS11B YBR048W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
RDH54 YBR073W DNA-dependent ATPase genetic 1 1 1 Negative Genetic
PBY1 YBR094W Putative tubulin tyrosine ligase associated with P-bodies genetic 1 1 1 Negative Genetic
MUD1 YBR119W U1 snRNP A protein genetic 1 1 1 Negative Genetic
SEC66 YBR171W Non-essential subunit of Sec63 complex genetic 1 1 1 Negative Genetic
SWC5 YBR231C Component of the SWR1 complex genetic 1 1 1 Negative Genetic
YBR238C YBR238C Mitochondrial membrane protein genetic 1 1 1 Negative Genetic
SGF29 YCL010C Component of the HAT/Core module of the SAGA, SLIK, and ADA complexes genetic 1 1 1 Negative Genetic
RIM1 YCR028C-A ssDNA-binding protein essential for mitochondrial genome maintenance genetic 1 1 1 Negative Genetic
SNT1 YCR033W Set3C histone deacetylase scaffold genetic 1 1 1 Negative Genetic
YCR102C YCR102C Putative quinone oxidoreductase genetic 1 1 1 Negative Genetic
PTC1 YDL006W Type 2C protein phosphatase (PP2C) genetic 1 1 1 Negative Genetic
PEX19 YDL065C Chaperone and import receptor for newly-synthesized class I PMPs genetic 1 1 1 Negative Genetic
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p genetic 1 1 1 Negative Genetic
YDL186W YDL186W Putative protein of unknown function genetic 1 1 1 Negative Genetic
VPS41 YDR080W Subunit of the HOPS endocytic tethering complex genetic 1 1 1 Negative Genetic
TMS1 YDR105C Vacuolar membrane protein of unknown function genetic 1 1 1 Negative Genetic
PEX10 YDR265W Peroxisomal membrane E3 ubiquitin ligase genetic 1 1 1 Negative Genetic
PHO92 YDR374C Posttranscriptional regulator of phosphate and glucose metabolism genetic 1 1 1 Negative Genetic
YDR476C YDR476C Putative protein of unknown function genetic 1 1 1 Negative Genetic
SCS2 YER120W Integral ER membrane protein, regulates phospholipid metabolism genetic 1 1 1 Negative Genetic
PDR1 YGL013C Transcription factor that regulates the pleiotropic drug response genetic 1 1 1 Negative Genetic
MMS2 YGL087C Ubiquitin-conjugating enzyme variant genetic 1 1 1 Negative Genetic
MON1 YGL124C Subunit of a heterodimeric guanine nucleotide exchange factor (GEF) genetic 1 1 1 Negative Genetic
VAM7 YGL212W Vacuolar SNARE protein genetic 1 1 1 Negative Genetic
MTC3 YGL226W Protein of unknown function genetic 1 1 1 Negative Genetic
RTF1 YGL244W Subunit of RNAPII-associated chromatin remodeling Paf1 complex genetic 1 1 1 Negative Genetic
MSB2 YGR014W Mucin family member involved in various signaling pathways genetic 1 1 1 Negative Genetic
MTL1 YGR023W Putative plasma membrane sensor genetic 1 1 1 Negative Genetic
YGR054W YGR054W Eukaryotic initiation factor eIF2A genetic 1 1 1 Negative Genetic
PAC10 YGR078C Part of the heteromeric co-chaperone GimC/prefoldin complex genetic 1 1 1 Negative Genetic
SOL4 YGR248W 6-phosphogluconolactonase genetic 1 1 1 Negative Genetic
SNF6 YHL025W Subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Negative Genetic
PTH1 YHR189W One of two mitochondrially-localized peptidyl-tRNA hydrolases genetic 1 1 1 Negative Genetic
SKN7 YHR206W Nuclear response regulator and transcription factor genetic 1 1 1 Negative Genetic
PUT3 YKL015W Transcriptional activator genetic 1 1 1 Negative Genetic
SAC1 YKL212W Phosphatidylinositol phosphate phosphatase genetic 1 1 1 Negative Genetic
SAP190 YKR028W Protein that forms a complex with the Sit4p protein phosphatase genetic 1 1 1 Negative Genetic
SET3 YKR029C Defining member of the SET3 histone deacetylase complex genetic 1 1 1 Negative Genetic
SRL3 YKR091W Repressor of transcription at Start genetic 1 1 1 Negative Genetic
PSR1 YLL010C Plasma membrane-associated protein phosphatase genetic 1 1 1 Negative Genetic
POM33 YLL023C Transmembrane nucleoporin genetic 1 1 1 Negative Genetic
VPS13 YLL040C Lipid transport protein involved in prospore membrane morphogenesis genetic 1 1 1 Negative Genetic
PCD1 YLR151C 8-oxo-dGTP diphosphatase genetic 1 1 1 Negative Genetic
YLR278C YLR278C Zinc-cluster protein genetic 1 1 1 Negative Genetic
TDA5 YLR426W Putative protein of unknown function genetic 1 1 1 Negative Genetic
UNG1 YML021C Uracil-DNA glycosylase genetic 1 1 1 Negative Genetic
YMR226C YMR226C NADP(+)-dependent serine dehydrogenase and carbonyl reductase genetic 1 1 1 Negative Genetic
UBP15 YMR304W Ubiquitin-specific protease involved in protein deubiquitination genetic 1 1 1 Negative Genetic
YOL036W YOL036W Protein of unknown function genetic 1 1 1 Negative Genetic
YOR131C YOR131C Putative haloacid dehalogenase-like hydrolase genetic 1 1 1 Negative Genetic
PMT3 YOR321W Protein O-mannosyltransferase genetic 1 1 1 Negative Genetic
PUT4 YOR348C Proline permease genetic 1 1 1 Negative Genetic
RAD1 YPL022W Single-stranded DNA endonuclease (with Rad10p) genetic 1 1 1 Negative Genetic
PPQ1 YPL179W Protein phosphatase that regulates the mating response genetic 1 1 1 Negative Genetic
RTC6 YPL183W-A Protein involved in translation genetic 1 1 1 Negative Genetic
YTA6 YPL074W Putative ATPase of the CDC48/PAS1/SEC18 (AAA) family genetic 1 1 1 Negative Genetic
TUB4 YLR212C Gamma-tubulin genetic 1 1 1 Synthetic Rescue
DIT2 YDR402C N-formyltyrosine oxidase genetic 1 1 1 Negative Genetic
HEM25 YDL119C Mitochondrial glycine transporter genetic 1 1 1 Negative Genetic
CSS3 YOL159C Protein of unknown function, secreted when constitutively expressed genetic 1 1 1 Negative Genetic
ATP23 YNR020C Putative metalloprotease of the mitochondrial inner membrane physical 1 1 1 Affinity Capture-MS