Standard name Systematic name Name description Description
FRK1 YPL141C Protein kinase of unknown cellular role Protein kinase of unknown cellular role; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; interacts with rRNA transcription and ribosome biogenesis factors and the long chain fatty acyl-CoA synthetase Faa3p; FRK1 has a paralog, KIN4, that arose from the whole genome duplication
Visualize the interactome of FRK1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)
G1(P) 2

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.951 0.971 0.981

GFP localization & abundance

GFP localization GFP abundance
no data no data

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
FRK1 0 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
KIN4 YOR233W Serine/threonine protein kinase genetic 6 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
FKH1 YIL131C Forkhead family transcription factor regulation 4 3 4 chromatin immunoprecipitation- exonuclease evidence, chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation- exonuclease evidence, ChEC-Seq experiments
FKH2 YNL068C Forkhead family transcription factor regulation 4 3 4 chromatin immunoprecipitation- exonuclease evidence, chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation- exonuclease evidence, ChEC-Seq experiments
DOT1 YDR440W Nucleosomal histone H3-Lys79 methylase genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
TPS2 YDR074W Phosphatase subunit of the trehalose-6-P synthase/phosphatase complex genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
PTK2 YJR059W Serine/threonine protein kinase genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
ASF1 YJL115W Nucleosome assembly factor genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
FKS1 YLR342W Catalytic subunit of 1,3-beta-D-glucan synthase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SSD1 YDR293C Translational repressor genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
RRP1 YDR087C Essential evolutionarily conserved nucleolar protein physical 2 2 2 Biochemical Activity, Affinity Capture-MS
WHI3 YNL197C RNA binding protein that modulates mRNA stability physical 2 2 2 Protein-RNA, Affinity Capture-RNA
IPL1 YPL209C Aurora kinase of chromosomal passenger complex genetic 2 2 2 Positive Genetic, Dosage Growth Defect
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
CLC1 YGR167W Clathrin light chain genetic 2 1 2 Negative Genetic, Negative Genetic
PUF3 YLL013C Protein of the mitochondrial outer surface physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
RPT2 YDL007W ATPase of the 19S regulatory particle of the 26S proteasome genetic 2 1 2 Negative Genetic, Negative Genetic
NOB1 YOR056C Protein involved in proteasomal and 40S ribosomal subunit biogenesis genetic 2 1 2 Negative Genetic, Negative Genetic
RPS27B YHR021C Protein component of the small (40S) ribosomal subunit genetic 2 1 2 Negative Genetic, Negative Genetic
SAC1 YKL212W Phosphatidylinositol phosphate phosphatase genetic 2 1 2 Negative Genetic, Negative Genetic
SOK2 YMR016C Nuclear protein that negatively regulates pseudohyphal differentiation genetic 2 1 2 Negative Genetic, Negative Genetic
YNL040W YNL040W Protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
IXR1 YKL032C Transcriptional repressor that regulates hypoxic genes during normoxia regulation 1 1 1 DNA to cDNA expression microarray evidence
HFI1 YPL254W Adaptor protein required for structural integrity of the SAGA complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAP6 YDR259C Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
TFC7 YOR110W RNA pol III transcription initiation factor complex (TFIIIC) subunit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit regulation 1 1 1 quantitative mass spectrometry evidence
INO2 YDR123C Transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
BFR2 YDR299W Component of the SSU and 90S preribosomes physical 1 1 1 Biochemical Activity
DRS1 YLL008W Nucleolar DEAD-box protein required for ribosome assembly and function physical 1 1 1 Biochemical Activity
ERB1 YMR049C Constituent of 66S pre-ribosomal particles physical 1 1 1 Affinity Capture-MS
BRE1 YDL074C E3 ubiquitin ligase physical 1 1 1 Biochemical Activity
CIC1 YHR052W Essential protein that interacts with proteasome components physical 1 1 1 Affinity Capture-MS
CDC33 YOL139C Translation initiation factor eIF4E physical 1 1 1 Biochemical Activity
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
ARP3 YJR065C Essential component of the Arp2/3 complex genetic 1 1 1 Positive Genetic
ASF1 YJL115W Nucleosome assembly factor physical 1 1 1 Biochemical Activity
BUD14 YAR014C Protein involved in bud-site selection genetic 1 1 1 Positive Genetic
CDC55 YGL190C Regulatory subunit B of protein phosphatase 2A (PP2A) genetic 1 1 1 Positive Genetic
CNS1 YBR155W TPR-containing co-chaperone physical 1 1 1 Biochemical Activity
EDE1 YBL047C Scaffold protein involved in the formation of early endocytic sites physical 1 1 1 Biochemical Activity
ELP2 YGR200C Subunit of Elongator complex genetic 1 1 1 Negative Genetic
ARP8 YOR141C Nuclear actin-related protein involved in chromatin remodeling physical 1 1 1 Biochemical Activity
DRE2 YKR071C Component of the cytosolic Fe-S protein assembly (CIA) machinery physical 1 1 1 Biochemical Activity
CRZ1 YNL027W Transcription factor, activates transcription of stress response genes physical 1 1 1 Reconstituted Complex
ADO1 YJR105W Adenosine kinase physical 1 1 1 Biochemical Activity
CDC15 YAR019C Hippo-like kinase of the Mitotic Exit Network physical 1 1 1 Biochemical Activity
ADE6 YGR061C Formylglycinamidine-ribonucleotide (FGAM)-synthetase genetic 1 1 1 Negative Genetic
APE2 YKL157W Aminopeptidase yscII genetic 1 1 1 Negative Genetic
BUD27 YFL023W Unconventional prefoldin protein involved in translation initiation physical 1 1 1 Biochemical Activity
ATG19 YOL082W Receptor protein for the cytoplasm-to-vacuole targeting (Cvt) pathway physical 1 1 1 Reconstituted Complex
AIM3 YBR108W Protein that inhibits barbed-end actin filament elongation physical 1 1 1 Biochemical Activity
CEP3 YMR168C Essential kinetochore protein genetic 1 1 1 Negative Genetic
AMD1 YML035C AMP deaminase physical 1 1 1 Biochemical Activity
DAL81 YIR023W Positive regulator of genes in multiple nitrogen degradation pathways genetic 1 1 1 Negative Genetic
CLC1 YGR167W Clathrin light chain physical 1 1 1 Biochemical Activity
CQD1 YPL109C UbiB family mitochondrial protein genetic 1 1 1 Negative Genetic
HSP82 YPL240C Hsp90 chaperone physical 1 1 1 Two-hybrid
HSP82 YPL240C Hsp90 chaperone genetic 1 1 1 Synthetic Growth Defect
TRL1 YJL087C tRNA ligase physical 1 1 1 Affinity Capture-MS
SAG1 YJR004C Alpha-agglutinin of alpha-cells physical 1 1 1 Affinity Capture-MS
YJR124C YJR124C Putative protein of unknown function physical 1 1 1 Affinity Capture-MS
SIS2 YKR072C Negative regulatory subunit of protein phosphatase 1 (Ppz1p) physical 1 1 1 Biochemical Activity
TDA1 YMR291W Protein kinase of unknown cellular role physical 1 1 1 Biochemical Activity
PAH1 YMR165C Mg2+-dependent phosphatidate (PA) phosphatase physical 1 1 1 Biochemical Activity
SEC2 YNL272C Guanyl-nucleotide exchange factor for the small G-protein Sec4p physical 1 1 1 Biochemical Activity
NAP1 YKR048C Histone chaperone and assembly chaperone for Rps6a/b physical 1 1 1 Biochemical Activity
IPA1 YJR141W Protein implicated in pre-mRNA processing and proteasomal degradation physical 1 1 1 Biochemical Activity
SSE2 YBR169C Member of Hsp110 subclass of the heat shock protein 70 (HSP70) family physical 1 1 1 Biochemical Activity
YMR155W YMR155W Putative protein of unknown function physical 1 1 1 Biochemical Activity
YML037C YML037C Putative protein of unknown function physical 1 1 1 Biochemical Activity
SPT16 YGL207W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) physical 1 1 1 Biochemical Activity
NHP10 YDL002C Non-essential INO80 chromatin remodeling complex subunit physical 1 1 1 Biochemical Activity
YAP3 YHL009C Basic leucine zipper (bZIP) transcription factor physical 1 1 1 Biochemical Activity
GLO3 YER122C ADP-ribosylation factor GTPase activating protein (ARF GAP) physical 1 1 1 Biochemical Activity
RNH70 YGR276C 3'-5' exoribonuclease physical 1 1 1 Biochemical Activity
SES1 YDR023W Cytosolic seryl-tRNA synthetase physical 1 1 1 Biochemical Activity
LEO1 YOR123C Component of the Paf1 complex physical 1 1 1 Biochemical Activity
VPS75 YNL246W NAP family histone chaperone physical 1 1 1 Biochemical Activity
SGS1 YMR190C RecQ family nucleolar DNA helicase physical 1 1 1 Biochemical Activity
QCR6 YFR033C Subunit 6 of the ubiquinol cytochrome-c reductase complex physical 1 1 1 Biochemical Activity
YNL284C-A YNL284C-A Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Biochemical Activity
RPB10 YOR210W RNA polymerase subunit ABC10-beta physical 1 1 1 Biochemical Activity
GUS1 YGL245W Glutamyl-tRNA synthetase (GluRS) physical 1 1 1 Biochemical Activity
NAB3 YPL190C RNA-binding protein, subunit of Nrd1 complex (Nrd1p-Nab3p-Sen1p) physical 1 1 1 Biochemical Activity
PDI1 YCL043C Protein disulfide isomerase physical 1 1 1 Biochemical Activity
RNA1 YMR235C GTPase activating protein (GAP) for Gsp1p physical 1 1 1 Biochemical Activity
RDI1 YDL135C Rho GDP dissociation inhibitor physical 1 1 1 Biochemical Activity
SLA1 YBL007C Cytoskeletal protein binding protein physical 1 1 1 Biochemical Activity
GIR2 YDR152W Highly-acidic RWD domain-containing cytoplasmic protein physical 1 1 1 Biochemical Activity
YOL107W YOL107W Putative protein of unknown function physical 1 1 1 Biochemical Activity
TRM13 YOL125W 2'-O-methyltransferase physical 1 1 1 Biochemical Activity
YJR142W YJR142W 8-oxo-dGTP diphosphatase of the Nudix hydrolase family physical 1 1 1 Biochemical Activity
HBT1 YDL223C Shmoo tip protein, substrate of Hub1p ubiquitin-like protein physical 1 1 1 Biochemical Activity
YPR137C-A YPR137C-A Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Biochemical Activity
PLP2 YOR281C Protein that interacts with the CCT complex to stimulate actin folding physical 1 1 1 Biochemical Activity
GUP1 YGL084C Plasma membrane protein involved in remodeling GPI anchors physical 1 1 1 Biochemical Activity
RAD2 YGR258C Single-stranded DNA endonuclease physical 1 1 1 Biochemical Activity
MST27 YGL051W Putative integral membrane protein, involved in vesicle formation physical 1 1 1 Biochemical Activity
PTC1 YDL006W Type 2C protein phosphatase (PP2C) physical 1 1 1 Biochemical Activity
SFC1 YJR095W Mitochondrial succinate-fumarate transporter physical 1 1 1 Biochemical Activity
HEK2 YBL032W RNA binding protein involved in asymmetric localization of ASH1 mRNA physical 1 1 1 Affinity Capture-RNA
LGE1 YPL055C Protein involved in histone H2B ubiquitination physical 1 1 1 Affinity Capture-MS
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
MAK21 YDR060W Constituent of 66S pre-ribosomal particles physical 1 1 1 Affinity Capture-MS
MAK5 YBR142W Essential nucleolar protein physical 1 1 1 Affinity Capture-MS
MAM33 YIL070C Acidic protein of the mitochondrial matrix physical 1 1 1 Affinity Capture-MS
MRM1 YOR201C Ribose methyltransferase physical 1 1 1 Affinity Capture-MS
NOP12 YOL041C Nucleolar protein involved in pre-25S rRNA processing physical 1 1 1 Affinity Capture-MS
NOP7 YGR103W Component of several different pre-ribosomal particles physical 1 1 1 Affinity Capture-MS
POL5 YEL055C Protein involved in 60S assembly and pre-40S AFs recycling physical 1 1 1 Affinity Capture-MS
PWP1 YLR196W Protein with WD-40 repeats involved in rRNA processing physical 1 1 1 Affinity Capture-MS
RLP7 YNL002C Nucleolar protein similar to large ribosomal subunit L7 proteins physical 1 1 1 Affinity Capture-MS
RPF2 YKR081C Essential protein involved in rRNA maturation and ribosomal assembly physical 1 1 1 Affinity Capture-MS
RRP12 YPL012W Protein required for export of the ribosomal subunits physical 1 1 1 Affinity Capture-MS
RRP14 YKL082C Essential protein, constituent of 66S pre-ribosomal particles physical 1 1 1 Affinity Capture-MS
TPA1 YER049W Prolyl hydroxylase physical 1 1 1 Affinity Capture-MS
GCD1 YOR260W Gamma subunit of the translation initiation factor eIF2B physical 1 1 1 Reconstituted Complex
GSY2 YLR258W Glycogen synthase physical 1 1 1 Reconstituted Complex
GSY2 YLR258W Glycogen synthase genetic 1 1 1 Dosage Growth Defect
NTA1 YJR062C Amidase physical 1 1 1 Reconstituted Complex
RAD23 YEL037C Protein with ubiquitin-like N terminus physical 1 1 1 Reconstituted Complex
RIM11 YMR139W Protein kinase physical 1 1 1 Reconstituted Complex
TIF2 YJL138C Translation initiation factor eIF4A physical 1 1 1 Reconstituted Complex
UBC8 YEL012W Ubiquitin-conjugating enzyme that regulates gluconeogenesis physical 1 1 1 Reconstituted Complex
WWM1 YFL010C WW domain containing protein of unknown function physical 1 1 1 Reconstituted Complex
YBR053C YBR053C Putative protein of unknown function physical 1 1 1 Reconstituted Complex
YGR017W YGR017W Putative protein of unknown function physical 1 1 1 Reconstituted Complex
YIG1 YPL201C Protein that interacts with glycerol 3-phosphatase physical 1 1 1 Reconstituted Complex
JJJ3 YJR097W Iron-binding protein physical 1 1 1 Reconstituted Complex
YJR154W YJR154W Putative protein of unknown function physical 1 1 1 Reconstituted Complex
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p physical 1 1 1 Affinity Capture-MS
MPT5 YGL178W mRNA-binding protein of the PUF family physical 1 1 1 Affinity Capture-RNA
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family genetic 1 1 1 Synthetic Growth Defect
YPD1 YDL235C Osmotic stress-responsive phosphorelay intermediate sensor protein genetic 1 1 1 Positive Genetic
SLN1 YIL147C Transmembrane histidine phosphotransfer kinase and osmosensor genetic 1 1 1 Positive Genetic
TEL2 YGR099W Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Positive Genetic
YNL144C YNL144C Putative protein of unknown function genetic 1 1 1 Dosage Growth Defect
YPR172W YPR172W Protein of unknown function genetic 1 1 1 Dosage Growth Defect
MDM30 YLR368W F-box component of an SCF ubiquitin protein ligase complex genetic 1 1 1 Dosage Growth Defect
REB1 YBR049C RNA polymerase I enhancer binding protein genetic 1 1 1 Positive Genetic
SEC20 YDR498C Membrane glycoprotein v-SNARE genetic 1 1 1 Positive Genetic
MLO127 YJR039W Mitochondrial protein of unknown function genetic 1 1 1 Positive Genetic
TIF34 YMR146C eIF3i subunit of the eukaryotic translation initiation factor 3 (eIF3) genetic 1 1 1 Negative Genetic
HSP10 YOR020C Mitochondrial matrix co-chaperonin genetic 1 1 1 Negative Genetic
RAT1 YOR048C Nuclear 5' to 3' single-stranded RNA exonuclease genetic 1 1 1 Negative Genetic
YTH1 YPR107C Essential RNA-binding component of cleavage and polyadenylation factor genetic 1 1 1 Negative Genetic
TVS1 YCR061W Protein of unknown function genetic 1 1 1 Negative Genetic
MRX14 YDR115W Putative mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
LSM6 YDR378C Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
PMR1 YGL167C High affinity Ca2+/Mn2+ P-type ATPase genetic 1 1 1 Negative Genetic
YGR210C YGR210C Putative protein of unknown function genetic 1 1 1 Negative Genetic
SLM1 YIL105C Phosphoinositide PI4,5P(2) binding protein, forms a complex with Slm2p genetic 1 1 1 Negative Genetic
SEI1 YLR404W Seipin involved in lipid droplet (LD) assembly genetic 1 1 1 Negative Genetic
GOT1 YMR292W Homodimeric protein that is packaged into COPII vesicles genetic 1 1 1 Negative Genetic
MIC27 YNL100W Component of the MICOS complex genetic 1 1 1 Negative Genetic
PCS60 YBR222C Oxalyl-CoA synthetase genetic 1 1 1 Negative Genetic
GID7 YCL039W Subunit of GID Complex that binds directly to central component Vid30p genetic 1 1 1 Negative Genetic
SNF6 YHL025W Subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Negative Genetic
YJR084W YJR084W Protein that forms a complex with Thp3p genetic 1 1 1 Negative Genetic
YNG2 YHR090C Subunit of NuA4, an essential histone acetyltransferase complex genetic 1 1 1 Positive Genetic
ILV1 YER086W Threonine deaminase, catalyzes first step in isoleucine biosynthesis genetic 1 1 1 Negative Genetic
BCH2 YKR027W Member of the ChAPs (Chs5p-Arf1p-binding proteins) family genetic 1 1 1 Dosage Growth Defect
ESBP6 YNL125C Protein with similarity to monocarboxylate permeases physical 1 1 1 Biochemical Activity
ANT1 YPR128C Peroxisomal adenine nucleotide transporter physical 1 1 1 Biochemical Activity
ATP14 YLR295C Subunit h of the F0 sector of mitochondrial F1F0 ATP synthase physical 1 1 1 Biochemical Activity
DDR48 YMR173W DNA damage-responsive protein physical 1 1 1 Biochemical Activity
ANB1 YJR047C Translation elongation factor eIF-5A physical 1 1 1 Reconstituted Complex
ELF1 YKL160W Transcription elongation factor with a conserved zinc finger domain physical 1 1 1 Biochemical Activity
ABP140 YOR239W AdoMet-dependent tRNA methyltransferase and actin binding protein physical 1 1 1 Biochemical Activity
APJ1 YNL077W Hsp40 chaperone with a role in SUMO-mediated protein degradation physical 1 1 1 Affinity Capture-MS
EMA35 YCR100C Protein involved in protein sorting physical 1 1 1 Biochemical Activity
COS4 YFL062W Endosomal protein involved in turnover of plasma membrane proteins physical 1 1 1 Biochemical Activity
DNF2 YDR093W Aminophospholipid translocase (flippase) genetic 1 1 1 Negative Genetic
FAA3 YIL009W Long chain fatty acyl-CoA synthetase physical 1 1 1 Affinity Capture-MS
DPI8 YJL133C-A Putative mitochondrial protein of unknown function genetic 1 1 1 Negative Genetic