Standard name Systematic name Name description Description
SLM1 YIL105C Phosphoinositide PI4,5P(2) binding protein, forms a complex with Slm2p Phosphoinositide PI4,5P(2) binding protein, forms a complex with Slm2p; acts downstream of Mss4p in a pathway regulating actin cytoskeleton organization in response to stress; TORC2 complex substrate and effector; protein abundance increases in response to DNA replication stress; SLM1 has a paralog, SLM2, that arose from the whole genome duplication
Visualize the interactome of SLM1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Bud 0.169 0.142 0.051
Cell Periphery 0.406 0.358 0.470
Cort. Patches 0.696 0.642 0.591
Cytoplasm 0.099 0.125 0.163
ER 0.064 0.125 0.084
Mito 0.099 0.071 NaN

GFP localization & abundance

GFP localization GFP abundance
no data no data

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
SLM1 0 0 0 2 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
SLM2 YNL047C Phosphoinositide PI4,5P(2) binding protein, forms a complex with Slm1p genetic 9 3 9 Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Negative Genetic, Phenotypic Enhancement, Negative Genetic, Synthetic Lethality, Negative Genetic, Negative Genetic
AVO2 YMR068W Component of a complex containing the Tor2p kinase and other proteins physical 5 3 4 Two-hybrid, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Reconstituted Complex
TOR2 YKL203C PIK-related protein kinase and rapamycin target physical 4 3 4 Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Biochemical Activity
CSG2 YBR036C Endoplasmic reticulum membrane protein genetic 4 3 2 Synthetic Lethality, Dosage Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
CNA1 YLR433C Calcineurin A physical 3 2 3 Affinity Capture-Western, Two-hybrid, Two-hybrid
BIT2 YBR270C Subunit of TORC2 membrane-associated complex physical 3 2 3 Two-hybrid, Reconstituted Complex, Two-hybrid
YPK1 YKL126W S/T protein kinase physical 3 2 3 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western
TSC11 YER093C Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p) genetic 3 2 3 Dosage Rescue, Dosage Rescue, Negative Genetic
SLM1 YIL105C Phosphoinositide PI4,5P(2) binding protein, forms a complex with Slm2p physical 3 2 3 PCA, Two-hybrid, PCA
RIC1 YLR039C Protein involved in retrograde transport to the cis-Golgi network genetic 3 1 3 Positive Genetic, Positive Genetic, Positive Genetic
TSC11 YER093C Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p) physical 3 1 3 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western
MSS4 YDR208W Phosphatidylinositol-4-phosphate 5-kinase genetic 3 3 2 Dosage Rescue, Synthetic Lethality, Negative Genetic
IMD3 YLR432W Inosine monophosphate dehydrogenase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
ELP2 YGR200C Subunit of Elongator complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
THP2 YHR167W Subunit of the THO and TREX complexes genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SHE4 YOR035C Protein containing a UCS (UNC-45/CRO1/SHE4) domain genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SLM2 YNL047C Phosphoinositide PI4,5P(2) binding protein, forms a complex with Slm1p physical 2 2 2 Two-hybrid, Affinity Capture-Western
NUT1 YGL151W Component of the RNA polymerase II mediator complex genetic 2 1 2 Negative Genetic, Negative Genetic
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
LST8 YNL006W Protein required for the transport of Gap1p genetic 2 1 2 Negative Genetic, Negative Genetic
INP2 YMR163C Peroxisome-specific receptor important for peroxisome inheritance genetic 2 1 2 Negative Genetic, Negative Genetic
MAM33 YIL070C Acidic protein of the mitochondrial matrix physical 2 1 2 PCA, PCA
RVS161 YCR009C Amphiphysin-like lipid raft protein genetic 2 1 2 Positive Genetic, Positive Genetic
HEF3 YNL014W Translational elongation factor EF-3 genetic 2 1 2 Negative Genetic, Negative Genetic
RVS167 YDR388W Calmodulin-binding actin-associated protein genetic 2 1 2 Positive Genetic, Positive Genetic
GRX5 YPL059W Glutathione-dependent oxidoreductase physical 2 1 2 Two-hybrid, Two-hybrid
PKC1 YBL105C Protein serine/threonine kinase genetic 2 1 2 Dosage Rescue, Dosage Rescue
SNC2 YOR327C Vesicle membrane receptor protein (v-SNARE) genetic 2 1 2 Negative Genetic, Negative Genetic
TAP42 YMR028W Essential protein involved in the TOR signaling pathway genetic 2 1 2 Negative Genetic, Negative Genetic
KTI12 YKL110C Protein that plays a role in modification of tRNA wobble nucleosides genetic 2 1 2 Negative Genetic, Negative Genetic
HAP4 YKL109W Transcription factor genetic 2 1 2 Negative Genetic, Negative Genetic
OSH3 YHR073W Member of an oxysterol-binding protein family genetic 2 1 2 Positive Genetic, Positive Genetic
PEX30 YLR324W ER-resident protein involved in peroxisomal biogenesis genetic 2 1 2 Negative Genetic, Negative Genetic
ASH1 YKL185W Component of the Rpd3L histone deacetylase complex genetic 2 1 2 Negative Genetic, Negative Genetic
RPS0A YGR214W Ribosomal 40S subunit protein S0A genetic 2 1 2 Negative Genetic, Negative Genetic
SAC7 YDR389W GTPase activating protein (GAP) for Rho1p genetic 2 1 2 Synthetic Rescue, Synthetic Rescue
MBA1 YBR185C Membrane-associated mitochondrial ribosome receptor genetic 2 1 2 Negative Genetic, Negative Genetic
PRM10 YJL108C Pheromone-regulated protein genetic 2 1 2 Negative Genetic, Negative Genetic
COM2 YER130C Transcription factor that binds IME1 Upstream Activation Signal (UAS) genetic 2 1 2 Negative Genetic, Negative Genetic
MSC3 YLR219W Protein of unknown function genetic 2 1 2 Positive Genetic, Positive Genetic
PEX8 YGR077C Intraperoxisomal organizer of the peroxisomal import machinery genetic 2 1 2 Negative Genetic, Negative Genetic
MYG1 YER156C Protein involved in mitochondrial function genetic 2 1 2 Negative Genetic, Negative Genetic
CBT1 YKL208W Protein involved in 5' RNA end processing genetic 2 1 2 Negative Genetic, Negative Genetic
MME1 YMR166C Transporter of the mitochondrial inner membrane that exports magnesium genetic 2 1 2 Negative Genetic, Negative Genetic
BIT61 YJL058C Subunit of TORC2 membrane-associated complex physical 2 2 1 Reconstituted Complex, Affinity Capture-Western
YAF9 YNL107W Subunit of NuA4 histone H4 acetyltransferase and SWR1 complexes genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
CHS5 YLR330W Component of the exomer complex genetic 2 1 1 Negative Genetic, Negative Genetic
HXT8 YJL214W Protein of unknown function with similarity to hexose transporters genetic 2 1 1 Negative Genetic, Negative Genetic
IXR1 YKL032C Transcriptional repressor that regulates hypoxic genes during normoxia regulation 1 1 1 DNA to cDNA expression microarray evidence
MED2 YDL005C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
BUR6 YER159C Subunit of a heterodimeric NC2 transcription regulator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
STP1 YDR463W Transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
REB1 YBR049C RNA polymerase I enhancer binding protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SUA7 YPR086W Transcription factor TFIIB regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SPT3 YDR392W Subunit of the SAGA and SAGA-like transcriptional regulatory complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RCK2 YLR248W Protein kinase involved in response to oxidative and osmotic stress physical 1 1 1 Affinity Capture-MS
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 1 1 1 Negative Genetic
PRE6 YOL038W Alpha 4 subunit of the 20S proteasome physical 1 1 1 Affinity Capture-MS
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
ECM16 YMR128W Essential DEAH-box ATP-dependent RNA helicase specific to U3 snoRNP physical 1 1 1 Affinity Capture-MS
ASC1 YMR116C G-protein beta subunit and guanine dissociation inhibitor for Gpa2p physical 1 1 1 Affinity Capture-MS
IML3 YBR107C Outer kinetochore protein and component of the Ctf19 complex physical 1 1 1 Two-hybrid
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
LAS17 YOR181W Actin assembly factor physical 1 1 1 Affinity Capture-MS
LCB2 YDR062W Component of serine palmitoyltransferase genetic 1 1 1 Negative Genetic
FAB1 YFR019W 1-phosphatidylinositol-3-phosphate 5-kinase genetic 1 1 1 Positive Genetic
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family genetic 1 1 1 Synthetic Growth Defect
GIM3 YNL153C Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Negative Genetic
GIM5 YML094W Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Negative Genetic
PDA1 YER178W E1 alpha subunit of the pyruvate dehydrogenase (PDH) complex genetic 1 1 1 Negative Genetic
HSP82 YPL240C Hsp90 chaperone genetic 1 1 1 Synthetic Growth Defect
PUB1 YNL016W Poly (A)+ RNA-binding protein physical 1 1 1 Affinity Capture-MS
PRE9 YGR135W Alpha 3 subunit of the 20S proteasome physical 1 1 1 Affinity Capture-MS
RKM1 YPL208W SET-domain lysine-N-methyltransferase physical 1 1 1 Affinity Capture-MS
PIL1 YGR086C Eisosome core component genetic 1 1 1 Phenotypic Enhancement
SEC26 YDR238C Essential beta-coat protein of the COPI coatomer genetic 1 1 1 Positive Genetic
MNN10 YDR245W Subunit of a Golgi mannosyltransferase complex genetic 1 1 1 Negative Genetic
SHE2 YKL130C RNA-binding protein that binds specific mRNAs and interacts with She3p physical 1 1 1 Two-hybrid
SIN3 YOL004W Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 1 1 1 Negative Genetic
SGV1 YPR161C Cyclin (Bur2p)-dependent protein kinase physical 1 1 1 Affinity Capture-MS
MKS1 YNL076W Pleiotropic negative transcriptional regulator genetic 1 1 1 Negative Genetic
BCK1 YJL095W MAPKKK acting in the protein kinase C signaling pathway physical 1 1 1 Affinity Capture-MS
SAW1 YAL027W 5'- and 3'-flap DNA binding protein physical 1 1 1 Affinity Capture-MS
HEK2 YBL032W RNA binding protein involved in asymmetric localization of ASH1 mRNA physical 1 1 1 Affinity Capture-RNA
RIO2 YNL207W Essential serine kinase involved in the processing of 20S pre-rRNA physical 1 1 1 Affinity Capture-MS
PUF3 YLL013C Protein of the mitochondrial outer surface physical 1 1 1 Affinity Capture-RNA
RHO2 YNL090W Non-essential small GTPase of the Rho/Rac family of Ras-like proteins genetic 1 1 1 Dosage Rescue
CAF20 YOR276W Phosphoprotein of the mRNA cap-binding complex physical 1 1 1 Affinity Capture-RNA
ATG17 YLR423C Scaffold protein responsible for phagophore assembly site organization physical 1 1 1 Two-hybrid
PLN1 YKR046C Perilipin, involved in formation and stability of lipid droplets genetic 1 1 1 Positive Genetic
CMP2 YML057W Calcineurin A physical 1 1 1 Two-hybrid
CNB1 YKL190W Calcineurin B genetic 1 1 1 Synthetic Rescue
PST2 YDR032C FMN-dependent NAD(P)H:quinone oxidoreductase physical 1 1 1 PCA
GET2 YER083C Subunit of the GET complex genetic 1 1 1 Positive Genetic
RGP1 YDR137W Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) genetic 1 1 1 Positive Genetic
PKH2 YOL100W Serine/threonine protein kinase genetic 1 1 1 Dosage Rescue
CBK1 YNL161W Serine/threonine protein kinase of the the RAM signaling network physical 1 1 1 Affinity Capture-MS
DMC1 YER179W Meiosis-specific recombinase required for double-strand break repair physical 1 1 1 Two-hybrid
RHO1 YPR165W GTP-binding protein of the rho subfamily of Ras-like proteins genetic 1 1 1 Dosage Rescue
KNS1 YLL019C Protein kinase involved in negative regulation of PolIII transcription genetic 1 1 1 Negative Genetic
GPA2 YER020W Nucleotide binding alpha subunit of the heterotrimeric G protein physical 1 1 1 PCA
SEC4 YFL005W Rab family GTPase genetic 1 1 1 Dosage Rescue
CLB2 YPR119W B-type cyclin involved in cell cycle progression physical 1 1 1 Affinity Capture-MS
MCK1 YNL307C Dual-specificity ser/thr and tyrosine protein kinase physical 1 1 1 Affinity Capture-MS
MCK1 YNL307C Dual-specificity ser/thr and tyrosine protein kinase genetic 1 1 1 Synthetic Growth Defect
LOS1 YKL205W Nuclear pore protein genetic 1 1 1 Negative Genetic
BIR1 YJR089W Subunit of chromosomal passenger complex (CPC) genetic 1 1 1 Positive Genetic
PKH1 YDR490C Serine/threonine protein kinase genetic 1 1 1 Dosage Rescue
DHR2 YKL078W Predominantly nucleolar DEAH-box ATP-dependent RNA helicase genetic 1 1 1 Positive Genetic
MTQ2 YDR140W S-adenosylmethionine-dependent methyltransferase physical 1 1 1 Affinity Capture-MS
MRX16 YDR132C Protein that associates with the large mitoribosomal subunit genetic 1 1 1 Negative Genetic
YSP2 YDR326C Sterol-binding protein physical 1 1 1 Two-hybrid
YPK1 YKL126W S/T protein kinase genetic 1 1 1 Synthetic Rescue
SPO12 YHR152W Nucleolar protein of unknown function physical 1 1 1 Two-hybrid
TPO2 YGR138C Polyamine transporter of the major facilitator superfamily physical 1 1 1 PCA
TUS1 YLR425W Guanine nucleotide exchange factor (GEF) that modulates Rho1p activity physical 1 1 1 Affinity Capture-Western
URN1 YPR152C Protein of unknown function containing WW and FF domains physical 1 1 1 Affinity Capture-MS
ULP2 YIL031W Peptidase that deconjugates Smt3/SUMO-1 peptides from proteins physical 1 1 1 Affinity Capture-MS
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p physical 1 1 1 Affinity Capture-MS
VTS1 YOR359W Flap-structured DNA-binding and RNA-binding protein physical 1 1 1 Affinity Capture-RNA
SRS2 YJL092W DNA helicase and DNA-dependent ATPase physical 1 1 1 Affinity Capture-MS
VMA9 YCL005W-A Vacuolar H+ ATPase subunit e of the V-ATPase V0 subcomplex genetic 1 1 1 Negative Genetic
YCL049C YCL049C Protein of unknown function genetic 1 1 1 Negative Genetic
VMS1 YDR049W Peptidyl-tRNA hydrolase that releases stalled peptides from ribosomes, genetic 1 1 1 Negative Genetic
YPT6 YLR262C Rab family GTPase genetic 1 1 1 Positive Genetic
YDJ1 YNL064C Type I HSP40 co-chaperone genetic 1 1 1 Negative Genetic
SUR1 YPL057C Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit genetic 1 1 1 Positive Genetic
TCA17 YEL048C Component of transport protein particle (TRAPP) complex II genetic 1 1 1 Negative Genetic
SLM3 YDL033C tRNA-specific 2-thiouridylase genetic 1 1 1 Negative Genetic
AIM4 YBR194W Protein proposed to be associated with the nuclear pore complex physical 1 1 1 Affinity Capture-MS
PEX10 YDR265W Peroxisomal membrane E3 ubiquitin ligase genetic 1 1 1 Negative Genetic
PEX5 YDR244W Peroxisomal membrane signal receptor for peroxisomal matrix proteins genetic 1 1 1 Negative Genetic
RPS13 YDR064W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS1A YLR441C Ribosomal protein of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPS8A YBL072C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS7A YOR096W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS22A YJL190C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
ELO2 YCR034W Fatty acid elongase, involved in sphingolipid biosynthesis genetic 1 1 1 Dosage Growth Defect
SFK1 YKL051W Protein that regulates phospholipid asymmetry at plasma membrane physical 1 1 1 PCA
SLA2 YNL243W Adaptor protein that links actin to clathrin and endocytosis genetic 1 1 1 Negative Genetic
MUD2 YKL074C Protein involved in early pre-mRNA splicing genetic 1 1 1 Negative Genetic
DOT1 YDR440W Nucleosomal histone H3-Lys79 methylase physical 1 1 1 Affinity Capture-MS
MID2 YLR332W O-glycosylated plasma membrane protein physical 1 1 1 PCA
MSB3 YNL293W Rab GTPase-activating protein genetic 1 1 1 Dosage Rescue
RPL31A YDL075W Ribosomal 60S subunit protein L31A physical 1 1 1 Affinity Capture-MS
PBI2 YNL015W Cytosolic inhibitor of vacuolar proteinase B (PRB1) genetic 1 1 1 Negative Genetic
HSV2 YGR223C Phosphatidylinositol 3,5-bisphosphate-binding protein genetic 1 1 1 Negative Genetic
RPS2 YGL123W Protein component of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
INP51 YIL002C Phosphatidylinositol 4,5-bisphosphate 5-phosphatase genetic 1 1 1 Synthetic Rescue
PDR12 YPL058C Plasma membrane ATP-binding cassette (ABC) transporter physical 1 1 1 PCA
RPS20 YHL015W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS14A YCR031C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS0A YGR214W Ribosomal 40S subunit protein S0A physical 1 1 1 Affinity Capture-MS
FRK1 YPL141C Protein kinase of unknown cellular role genetic 1 1 1 Negative Genetic
HNM1 YGL077C Plasma membrane transporter for choline, ethanolamine, and carnitine physical 1 1 1 PCA
PAM17 YKR065C Constituent of the TIM23 complex genetic 1 1 1 Negative Genetic
PAH1 YMR165C Mg2+-dependent phosphatidate (PA) phosphatase genetic 1 1 1 Negative Genetic
DRN1 YGR093W Splicing factor that modulates turnover of branched RNAs by Dbr1p genetic 1 1 1 Negative Genetic
IFA38 YBR159W Microsomal beta-keto-reductase physical 1 1 1 Affinity Capture-MS
RAD34 YDR314C Protein involved in nucleotide excision repair (NER) physical 1 1 1 Affinity Capture-MS
SAC1 YKL212W Phosphatidylinositol phosphate phosphatase genetic 1 1 1 Negative Genetic
NCW2 YLR194C GPI-anchored protein involved in cell wall remodeling genetic 1 1 1 Negative Genetic
GIS2 YNL255C Translational activator for mRNAs with internal ribosome entry sites physical 1 1 1 Affinity Capture-MS
RPS6A YPL090C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS9A YPL081W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS10A YOR293W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RFS1 YBR052C Protein of unknown function physical 1 1 1 PCA
RPL26A YLR344W Ribosomal 60S subunit protein L26A physical 1 1 1 Affinity Capture-MS
RPS12 YOR369C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS19A YOL121C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS27A YKL156W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
DCR2 YLR361C Protein phosphatase genetic 1 1 1 Negative Genetic
FMP45 YDL222C Integral membrane protein localized to mitochondria physical 1 1 1 PCA
MUP1 YGR055W High affinity methionine permease physical 1 1 1 PCA
DUR3 YHL016C Plasma membrane transporter for both urea and polyamines physical 1 1 1 PCA
MRL1 YPR079W Membrane protein genetic 1 1 1 Negative Genetic
ISC1 YER019W Inositol phosphosphingolipid phospholipase C genetic 1 1 1 Synthetic Rescue
AVT5 YBL089W Putative transporter genetic 1 1 1 Negative Genetic
LCB4 YOR171C Sphingoid long-chain base kinase genetic 1 1 1 Dosage Growth Defect
MRM2 YGL136C Mitochondrial 2' O-ribose methyltransferase genetic 1 1 1 Positive Genetic
PSD1 YNL169C Phosphatidylserine decarboxylase of the mitochondrial inner membrane genetic 1 1 1 Positive Genetic
LAS21 YJL062W Mannose-ethanolamine phosphotransferase genetic 1 1 1 Positive Genetic
RPS15 YOL040C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RCF2 YNR018W Cytochrome c oxidase subunit genetic 1 1 1 Negative Genetic
PCP1 YGR101W Mitochondrial serine protease genetic 1 1 1 Negative Genetic