Standard name Systematic name Name description Description
MID2 YLR332W O-glycosylated plasma membrane protein O-glycosylated plasma membrane protein; acts as a sensor for cell wall integrity signaling and activates the pathway; interacts with Rom2p, a guanine nucleotide exchange factor for Rho1p, and with cell integrity pathway protein Zeo1p; MID2 has a paralog, MTL1, that arose from the whole genome duplication
Visualize the interactome of MID2
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cell Periphery 0.929 0.743 0.856
Cort. Patches 0.145 0.349 0.369
Mito 0.160 0.385 0.321
Cytoplasm NaN 0.110 0.069

GFP localization & abundance

GFP localization GFP abundance
cell periphery low signal

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
MID2 1 0 0 1 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
SLG1 YOR008C Sensor-transducer of the stress-activated PKC1-MPK1 kinase pathway genetic 15 5 11 Synthetic Lethality, Dosage Rescue, Dosage Rescue, Dosage Rescue, Synthetic Lethality, Phenotypic Enhancement, Dosage Rescue, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
SMI1 YGR229C Protein involved in the regulation of cell wall synthesis genetic 11 3 7 Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic
CCW12 YLR110C Cell wall mannoprotein genetic 7 3 6 Synthetic Lethality, Synthetic Lethality, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic
RGD1 YBR260C GTPase-activating protein (RhoGAP) for Rho3p and Rho4p genetic 6 3 5 Phenotypic Enhancement, Synthetic Lethality, Negative Genetic, Negative Genetic, Synthetic Lethality, Negative Genetic
MTL1 YGR023W Putative plasma membrane sensor genetic 5 4 4 Dosage Rescue, Dosage Rescue, Synthetic Growth Defect, Phenotypic Enhancement, Phenotypic Suppression
FKS1 YLR342W Catalytic subunit of 1,3-beta-D-glucan synthase genetic 5 1 4 Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality
ROM2 YLR371W Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p genetic 5 2 3 Synthetic Lethality, Dosage Rescue, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality
RHO1 YPR165W GTP-binding protein of the rho subfamily of Ras-like proteins genetic 4 1 4 Dosage Rescue, Dosage Rescue, Dosage Rescue, Dosage Rescue
SAC7 YDR389W GTPase activating protein (GAP) for Rho1p genetic 4 3 3 Dosage Lethality, Synthetic Rescue, Positive Genetic, Positive Genetic
SAC6 YDR129C Fimbrin, actin-bundling protein genetic 4 3 3 Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect, Negative Genetic
VAN1 YML115C Component of the mannan polymerase I genetic 4 3 3 Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect, Negative Genetic
FPS1 YLL043W Aquaglyceroporin, plasma membrane channel genetic 4 3 3 Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect, Dosage Rescue
ILM1 YJR118C Protein of unknown function genetic 4 2 3 Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Negative Genetic
OST6 YML019W Subunit of the oligosaccharyltransferase complex of the ER lumen genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
HOC1 YJR075W Alpha-1,6-mannosyltransferase genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
DEP1 YAL013W Component of the Rpd3L histone deacetylase complex genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
AIM44 YPL158C Regulator of Cdc42p and Rho1p genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
GAS1 YMR307W Beta-1,3-glucanosyltransferase required for cell wall assembly genetic 3 2 3 Synthetic Lethality, Negative Genetic, Negative Genetic
SYP1 YCR030C Negative regulator of WASP-Arp23 complex physical 3 2 3 PCA, Reconstituted Complex, Reconstituted Complex
GUP1 YGL084C Plasma membrane protein involved in remodeling GPI anchors genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
PST2 YDR032C FMN-dependent NAD(P)H:quinone oxidoreductase physical 3 3 2 PCA, Two-hybrid, Affinity Capture-MS
HEK2 YBL032W RNA binding protein involved in asymmetric localization of ASH1 mRNA physical 3 2 2 Affinity Capture-RNA, Protein-RNA, Affinity Capture-RNA
SLT2 YHR030C Serine/threonine MAP kinase genetic 3 2 2 Dosage Rescue, Dosage Rescue, Phenotypic Suppression
PKC1 YBL105C Protein serine/threonine kinase genetic 3 2 2 Dosage Rescue, Negative Genetic, Negative Genetic
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
CDC11 YJR076C Component of the septin ring that is required for cytokinesis genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
ACK1 YDL203C Protein that functions in the cell wall integrity pathway genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SDS3 YIL084C Component of the Rpd3L histone deacetylase complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
OPI3 YJR073C Methylene-fatty-acyl-phospholipid synthase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SAP30 YMR263W Component of Rpd3L histone deacetylase complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SEC63 YOR254C Essential subunit of Sec63 complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
CSF1 YLR087C Protein with structural similarity to lipid transport protein Vps13p genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
HTD2 YHR067W Mitochondrial 3-hydroxyacyl-thioester dehydratase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
GPI17 YDR434W Transmembrane protein genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
FUS2 YMR232W Cell fusion regulator genetic 3 2 1 Phenotypic Suppression, Phenotypic Suppression, Synthetic Rescue
STE12 YHR084W Transcription factor that is activated by a MAPK signaling cascade regulation 2 2 2 chromatin immunoprecipitation-chip evidence, DNA to cDNA expression microarray evidence
KAR3 YPR141C Minus-end-directed microtubule motor genetic 2 2 2 Dosage Rescue, Negative Genetic
GWT1 YJL091C Protein involved in the inositol acylation of GlcN-PI genetic 2 1 2 Negative Genetic, Negative Genetic
DBP7 YKR024C Putative ATP-dependent RNA helicase of the DEAD-box family genetic 2 1 2 Negative Genetic, Negative Genetic
ANP1 YEL036C Subunit of the alpha-1,6 mannosyltransferase complex genetic 2 1 2 Negative Genetic, Negative Genetic
MIC19 YFR011C Component of the MICOS complex genetic 2 1 2 Negative Genetic, Negative Genetic
ACA1 YER045C ATF/CREB family basic leucine zipper (bZIP) transcription factor genetic 2 1 2 Negative Genetic, Negative Genetic
ASK10 YGR097W Regulator of the Fps1p glycerol channel genetic 2 1 2 Positive Genetic, Positive Genetic
ZEO1 YOL109W Peripheral membrane protein of the plasma membrane physical 2 1 2 Two-hybrid, Two-hybrid
OSH7 YHR001W Oxysterol-binding phosphatidylserine transferase physical 2 1 2 PCA, PCA
WSC2 YNL283C Sensor-transducer of the stress-activated PKC1-MPK1 signaling pathway genetic 2 1 2 Dosage Rescue, Dosage Rescue
PFY1 YOR122C Profilin genetic 2 1 2 Dosage Rescue, Dosage Rescue
PDB1 YBR221C E1 beta subunit of the pyruvate dehydrogenase (PDH) complex genetic 2 1 2 Negative Genetic, Negative Genetic
SWI5 YDR146C Transcription factor that recruits Mediator and Swi/Snf complexes genetic 2 1 2 Negative Genetic, Negative Genetic
MNN10 YDR245W Subunit of a Golgi mannosyltransferase complex genetic 2 1 2 Negative Genetic, Negative Genetic
PAH1 YMR165C Mg2+-dependent phosphatidate (PA) phosphatase genetic 2 1 2 Negative Genetic, Negative Genetic
PBR1 YNL181W Putative oxidoreductase genetic 2 1 2 Negative Genetic, Negative Genetic
SEC66 YBR171W Non-essential subunit of Sec63 complex genetic 2 1 2 Negative Genetic, Negative Genetic
MNN11 YJL183W Subunit of a Golgi mannosyltransferase complex genetic 2 1 2 Negative Genetic, Negative Genetic
MDM1 YML104C PtdIns-3-P binding protein that tethers the ER to vacuoles at NVJs genetic 2 1 2 Negative Genetic, Negative Genetic
ERI1 YPL096C-A Endoplasmic reticulum membrane protein that binds and inhibits Ras2p genetic 2 1 2 Negative Genetic, Negative Genetic
GPI8 YDR331W Catalytic subunit of the ER membrane GPI transamidase complex genetic 2 1 2 Negative Genetic, Negative Genetic
CRN1 YLR429W Coronin physical 2 2 1 Two-hybrid, Affinity Capture-MS
ABP1 YCR088W Actin-binding protein of the cortical actin cytoskeleton physical 2 2 1 Two-hybrid, Affinity Capture-MS
KRE6 YPR159W Glucosyl hydrolase required for beta-1,6-glucan biosynthesis genetic 2 2 1 Synthetic Rescue, Phenotypic Enhancement
YCK1 YHR135C Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform physical 2 2 1 Two-hybrid, Affinity Capture-MS
RPL40A YIL148W Ubiquitin-ribosomal 60S subunit protein L40A fusion protein physical 2 2 1 Two-hybrid, Affinity Capture-MS
SSO2 YMR183C Plasma membrane t-SNARE physical 2 2 1 Two-hybrid, Affinity Capture-MS
RAS2 YNL098C GTP-binding protein physical 2 2 1 Two-hybrid, Affinity Capture-MS
STH1 YIL126W ATPase component of the RSC chromatin remodeling complex genetic 2 2 1 Dosage Rescue, Phenotypic Suppression
FUS1 YCL027W Membrane protein localized to the shmoo tip genetic 2 2 1 Synthetic Rescue, Phenotypic Suppression
IPP1 YBR011C Cytoplasmic inorganic pyrophosphatase (PPase) genetic 2 1 1 Negative Genetic, Negative Genetic
ERG27 YLR100W 3-keto sterol reductase genetic 2 1 1 Negative Genetic, Negative Genetic
GPI16 YHR188C Subunit of the glycosylphosphatidylinositol transamidase complex genetic 2 1 1 Negative Genetic, Negative Genetic
STT3 YGL022W Catalytic subunit of the oligosaccharyltransferase complex of the ER l genetic 2 1 1 Negative Genetic, Negative Genetic
MVD1 YNR043W Mevalonate pyrophosphate decarboxylase genetic 2 1 1 Negative Genetic, Negative Genetic
OST4 YDL232W Subunit of the oligosaccharyltransferase complex of the ER lumen genetic 2 1 1 Negative Genetic, Negative Genetic
GPI2 YPL076W Protein involved in the synthesis of GlcNAc-PI genetic 2 1 1 Negative Genetic, Negative Genetic
GPI19 YDR437W Subunit of GPI-GlcNAc transferase involved in synthesis of GlcNAc-PI genetic 2 1 1 Negative Genetic, Negative Genetic
ERG9 YHR190W Farnesyl-diphosphate farnesyl transferase (squalene synthase) genetic 2 1 1 Negative Genetic, Negative Genetic
GPI10 YGL142C Integral membrane protein involved in GPI anchor synthesis genetic 2 1 1 Negative Genetic, Negative Genetic
GPI11 YDR302W ER membrane protein involved in a late step of GPI anchor assembly genetic 2 1 1 Negative Genetic, Negative Genetic
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
IXR1 YKL032C Transcriptional repressor that regulates hypoxic genes during normoxia regulation 1 1 1 DNA to cDNA expression microarray evidence
TEC1 YBR083W Transcription factor targeting filamentation genes and Ty1 expression regulation 1 1 1 DNA to cDNA expression microarray evidence
FKH2 YNL068C Forkhead family transcription factor regulation 1 1 1 ChEC-Seq experiments
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p) regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SWI6 YLR182W Transcription cofactor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RLM1 YPL089C MADS-box transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CWC25 YNL245C Splicing factor required for the first step of pre-mRNA splicing genetic 1 1 1 Negative Genetic
GLC7 YER133W Type 1 S/T protein phosphatase (PP1) catalytic subunit genetic 1 1 1 Dosage Rescue
CDC42 YLR229C Small rho-like GTPase genetic 1 1 1 Synthetic Rescue
BMH1 YER177W 14-3-3 protein, major isoform genetic 1 1 1 Dosage Rescue
CFT2 YLR115W Subunit of the mRNA cleavage and polyadenlylation factor (CPF) genetic 1 1 1 Negative Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
ARC35 YNR035C Subunit of the ARP2/3 complex genetic 1 1 1 Negative Genetic
ARP3 YJR065C Essential component of the Arp2/3 complex genetic 1 1 1 Negative Genetic
CDC24 YAL041W Guanine nucleotide exchange factor (GEF) for Cdc42p genetic 1 1 1 Negative Genetic
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit genetic 1 1 1 Dosage Lethality
BNI1 YNL271C Formin genetic 1 1 1 Phenotypic Suppression
CLP1 YOR250C Component of the cleavage and polyadenylation factor I (CF I) genetic 1 1 1 Negative Genetic
DCP1 YOL149W Subunit of the Dcp1p-Dcp2p decapping enzyme complex genetic 1 1 1 Positive Genetic
FPR1 YNL135C Peptidyl-prolyl cis-trans isomerase (PPIase) physical 1 1 1 Two-hybrid
CCT4 YDL143W Subunit of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Negative Genetic
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
LCB1 YMR296C Component of serine palmitoyltransferase physical 1 1 1 PCA
LCB2 YDR062W Component of serine palmitoyltransferase genetic 1 1 1 Negative Genetic
FAB1 YFR019W 1-phosphatidylinositol-3-phosphate 5-kinase genetic 1 1 1 Negative Genetic
FBA1 YKL060C Fructose 1,6-bisphosphate aldolase physical 1 1 1 Two-hybrid
MHR1 YDR296W Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
MAM33 YIL070C Acidic protein of the mitochondrial matrix physical 1 1 1 PCA
GIN4 YDR507C Protein kinase involved in bud growth and assembly of the septin ring physical 1 1 1 PCA
BGL2 YGR282C Endo-beta-1,3-glucanase physical 1 1 1 Affinity Capture-Western
BCK1 YJL095W MAPKKK acting in the protein kinase C signaling pathway genetic 1 1 1 Dosage Rescue
BRO1 YPL084W Cytoplasmic class E vacuolar protein sorting (VPS) factor genetic 1 1 1 Negative Genetic
EGD2 YHR193C Alpha subunit of the nascent polypeptide-associated complex (NAC) physical 1 1 1 Two-hybrid
GAS1 YMR307W Beta-1,3-glucanosyltransferase required for cell wall assembly physical 1 1 1 Affinity Capture-Western
BBC1 YJL020C Protein possibly involved in assembly of actin patches physical 1 1 1 PCA
LSP1 YPL004C Eisosome core component physical 1 1 1 PCA
HYP2 YEL034W Translation elongation factor eIF-5A genetic 1 1 1 Dosage Rescue
CNB1 YKL190W Calcineurin B genetic 1 1 1 Negative Genetic
EGD1 YPL037C Subunit beta1 of the nascent polypeptide-associated complex (NAC) physical 1 1 1 Two-hybrid
CDC9 YDL164C DNA ligase I found in nucleus and mitochondria genetic 1 1 1 Positive Genetic
COF1 YLL050C Cofilin, involved in pH-dependent actin filament depolarization physical 1 1 1 Two-hybrid
LIA1 YJR070C Deoxyhypusine hydroxylase genetic 1 1 1 Positive Genetic
GPA2 YER020W Nucleotide binding alpha subunit of the heterotrimeric G protein physical 1 1 1 PCA
MAK11 YKL021C Protein involved in an early step of 60S ribosomal subunit biogenesis genetic 1 1 1 Negative Genetic
CDC4 YFL009W F-box protein required for both the G1/S and G2/M phase transitions genetic 1 1 1 Negative Genetic
GRX1 YCL035C Glutathione-dependent disulfide oxidoreductase physical 1 1 1 Two-hybrid
GRX1 YCL035C Glutathione-dependent disulfide oxidoreductase genetic 1 1 1 Synthetic Growth Defect
MEK1 YOR351C Meiosis-specific serine/threonine protein kinase physical 1 1 1 Two-hybrid
CIK1 YMR198W Kinesin-associated protein genetic 1 1 1 Dosage Rescue
CDH1 YGL003C Activator of anaphase-promoting complex/cyclosome (APC/C) genetic 1 1 1 Negative Genetic
ERG11 YHR007C Lanosterol 14-alpha-demethylase physical 1 1 1 PCA
EXG1 YLR300W Major exo-1,3-beta-glucanase of the cell wall genetic 1 1 1 Negative Genetic
APM4 YOL062C Cargo-binding mu subunit of AP-2 physical 1 1 1 Reconstituted Complex
KEG1 YFR042W Integral membrane protein of the ER genetic 1 1 1 Positive Genetic
BOS1 YLR078C v-SNARE (vesicle specific SNAP receptor) genetic 1 1 1 Negative Genetic
ELP3 YPL086C Subunit of Elongator complex genetic 1 1 1 Dosage Rescue
HSF1 YGL073W Trimeric heat shock transcription factor genetic 1 1 1 Dosage Rescue
ZEO1 YOL109W Peripheral membrane protein of the plasma membrane genetic 1 1 1 Dosage Growth Defect
ROM2 YLR371W Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p physical 1 1 1 Two-hybrid
SHE2 YKL130C RNA-binding protein that binds specific mRNAs and interacts with She3p physical 1 1 1 Affinity Capture-RNA
RIM1 YCR028C-A ssDNA-binding protein essential for mitochondrial genome maintenance physical 1 1 1 PCA
OLE1 YGL055W Delta(9) fatty acid desaturase physical 1 1 1 PCA
SDS23 YGL056C Protein involved in cell separation during budding physical 1 1 1 PCA
YGL108C YGL108C Protein of unknown function, predicted to be palmitoylated physical 1 1 1 PCA
MUP1 YGR055W High affinity methionine permease physical 1 1 1 PCA
VHT1 YGR065C High-affinity plasma membrane H+-biotin (vitamin H) symporter physical 1 1 1 PCA
TPO2 YGR138C Polyamine transporter of the major facilitator superfamily physical 1 1 1 PCA
SMI1 YGR229C Protein involved in the regulation of cell wall synthesis physical 1 1 1 PCA
YOR1 YGR281W Plasma membrane ATP-binding cassette (ABC) transporter physical 1 1 1 PCA
SLM1 YIL105C Phosphoinositide PI4,5P(2) binding protein, forms a complex with Slm2p physical 1 1 1 PCA
QDR2 YIL121W Plasma membrane transporter of the major facilitator superfamily physical 1 1 1 PCA
SFK1 YKL051W Protein that regulates phospholipid asymmetry at plasma membrane physical 1 1 1 PCA
TPO1 YLL028W Polyamine transporter of the major facilitator superfamily physical 1 1 1 PCA
PIN2 YOR104W Exomer-dependent cargo protein physical 1 1 1 PCA
WSC3 YOL105C Sensor-transducer of the stress-activated PKC1-MPK1 signaling pathway physical 1 1 1 PCA
TPO4 YOR273C Polyamine transporter of the major facilitator superfamily physical 1 1 1 PCA
RSN1 YMR266W Membrane protein of unknown function physical 1 1 1 PCA
WSC2 YNL283C Sensor-transducer of the stress-activated PKC1-MPK1 signaling pathway physical 1 1 1 PCA
MID2 YLR332W O-glycosylated plasma membrane protein physical 1 1 1 PCA
PPZ1 YML016C Serine/threonine protein phosphatase Z, isoform of Ppz2p physical 1 1 1 PCA
PPZ1 YML016C Serine/threonine protein phosphatase Z, isoform of Ppz2p genetic 1 1 1 Synthetic Growth Defect
PDR12 YPL058C Plasma membrane ATP-binding cassette (ABC) transporter physical 1 1 1 PCA
TCB3 YML072C Cortical ER protein involved in ER-plasma membrane tethering physical 1 1 1 PCA
RTS1 YOR014W B-type regulatory subunit of protein phosphatase 2A (PP2A) physical 1 1 1 PCA
MYO5 YMR109W One of two type I myosin motors physical 1 1 1 PCA
WHI3 YNL197C RNA binding protein that modulates mRNA stability physical 1 1 1 Protein-RNA
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
PEP12 YOR036W Target membrane receptor (t-SNARE) physical 1 1 1 Co-purification
PMA1 YGL008C Plasma membrane P2-type H+-ATPase physical 1 1 1 Affinity Capture-Western
PUF2 YPR042C PUF family mRNA-binding protein physical 1 1 1 Affinity Capture-RNA
RHO5 YNL180C Non-essential small GTPase of the Rho/Rac family of Ras-like proteins physical 1 1 1 PCA
PAR32 YDL173W Low complexity protein physical 1 1 1 Two-hybrid
SSB1 YDL229W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Two-hybrid
MSH6 YDR097C Protein required for mismatch repair in mitosis and meiosis physical 1 1 1 Two-hybrid
RPL24A YGL031C Ribosomal 60S subunit protein L24A physical 1 1 1 Two-hybrid
MTR3 YGR158C Exosome non-catalytic core component physical 1 1 1 Two-hybrid
PDC1 YLR044C Major of three pyruvate decarboxylase isozymes physical 1 1 1 Two-hybrid
RPS0B YLR048W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Two-hybrid
RPS31 YLR167W Fusion protein cleaved to yield ribosomal protein S31 and ubiquitin physical 1 1 1 Two-hybrid
RAS2 YNL098C GTP-binding protein genetic 1 1 1 Synthetic Growth Defect
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Two-hybrid
YPL199C YPL199C Protein involved in nonstop mRNA decay physical 1 1 1 Two-hybrid
TEF1 YPR080W Translational elongation factor EF-1 alpha physical 1 1 1 Two-hybrid
PGA3 YML125C Putative cytochrome b5 reductase, localized to the plasma membrane physical 1 1 1 Affinity Capture-MS
SLT2 YHR030C Serine/threonine MAP kinase physical 1 1 1 PCA
PMT2 YAL023C Protein O-mannosyltransferase of the ER membrane genetic 1 1 1 Dosage Rescue
PMT4 YJR143C Protein O-mannosyltransferase genetic 1 1 1 Dosage Rescue
SLY1 YDR189W Hydrophilic protein involved in ER/Golgi vesicle trafficking genetic 1 1 1 Dosage Rescue
SPC110 YDR356W Inner plaque spindle pole body (SPB) component genetic 1 1 1 Dosage Rescue
MKK1 YOR231W MAPKK involved in the protein kinase C signaling pathway genetic 1 1 1 Dosage Rescue
RHO2 YNL090W Non-essential small GTPase of the Rho/Rac family of Ras-like proteins genetic 1 1 1 Dosage Rescue
YDJ1 YNL064C Type I HSP40 co-chaperone genetic 1 1 1 Dosage Rescue
SHO1 YER118C Transmembrane osmosensor for filamentous growth and HOG pathways genetic 1 1 1 Phenotypic Suppression
TSC13 YDL015C Enoyl reductase genetic 1 1 1 Negative Genetic
SSY1 YDR160W Component of the SPS plasma membrane amino acid sensor system genetic 1 1 1 Negative Genetic
POL5 YEL055C Protein involved in 60S assembly and pre-40S AFs recycling genetic 1 1 1 Negative Genetic
SEC9 YGR009C t-SNARE protein required for secretory vesicle-plasma membrane fusion genetic 1 1 1 Negative Genetic
RXT2 YBR095C Component of the histone deacetylase Rpd3L complex genetic 1 1 1 Negative Genetic
RPO41 YFL036W Mitochondrial RNA polymerase genetic 1 1 1 Negative Genetic
ORM1 YGR038W Protein that mediates sphingolipid homeostasis genetic 1 1 1 Phenotypic Suppression
ORM2 YLR350W Protein that mediates sphingolipid homeostasis genetic 1 1 1 Phenotypic Suppression
SPF1 YEL031W P-type ATPase, ion transporter of the ER membrane genetic 1 1 1 Negative Genetic
RPT3 YDR394W ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Positive Genetic
NOP53 YPL146C Nucleolar protein genetic 1 1 1 Positive Genetic
RER2 YBR002C Forms the dehydrodolichyl diphosphate synthase (DDS) complex with NUS1 genetic 1 1 1 Negative Genetic
POP4 YBR257W Subunit of both RNase MRP and nuclear RNase P genetic 1 1 1 Negative Genetic
SEC1 YDR164C Sm-like protein involved in docking and fusion of exocytic vesicles genetic 1 1 1 Negative Genetic
SEC20 YDR498C Membrane glycoprotein v-SNARE genetic 1 1 1 Negative Genetic
PMI40 YER003C Mannose-6-phosphate isomerase genetic 1 1 1 Negative Genetic
NTF2 YER009W Nuclear envelope protein genetic 1 1 1 Negative Genetic
SSC1 YJR045C Hsp70 family ATPase genetic 1 1 1 Negative Genetic
NUP116 YMR047C FG-nucleoporin component of central core of the nuclear pore complex genetic 1 1 1 Negative Genetic
RNT1 YMR239C Nuclear dsRNA-specific ribonuclease (RNase III) genetic 1 1 1 Negative Genetic
RAP1 YNL216W Essential DNA-binding transcription regulator that binds many loci genetic 1 1 1 Negative Genetic
NOG1 YPL093W Putative GTPase genetic 1 1 1 Negative Genetic
QRI1 YDL103C UDP-N-acetylglucosamine pyrophosphorylase genetic 1 1 1 Negative Genetic
SWC4 YGR002C Component of the Swr1p complex that incorporates Htz1p into chromatin genetic 1 1 1 Negative Genetic
RGR1 YLR071C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
RNA1 YMR235C GTPase activating protein (GAP) for Gsp1p genetic 1 1 1 Negative Genetic
OST2 YOR103C Epsilon subunit of the oligosaccharyltransferase complex genetic 1 1 1 Negative Genetic
SEC16 YPL085W COPII vesicle coat protein required for ER transport vesicle budding genetic 1 1 1 Negative Genetic
NSL1 YPL233W Essential component of the MIND kinetochore complex genetic 1 1 1 Negative Genetic
PHO13 YDL236W Conserved phosphatase acting as a metabolite repair enzyme genetic 1 1 1 Negative Genetic
PAL1 YDR348C Protein of unknown function thought to be involved in endocytosis genetic 1 1 1 Negative Genetic
UBC6 YER100W Ubiquitin-conjugating enzyme involved in ERAD genetic 1 1 1 Negative Genetic
SNG1 YGR197C Protein involved in resistance to nitrosoguanidine and 6-azauracil genetic 1 1 1 Negative Genetic
YHR050W-A YHR050W-A Protein of unknown function genetic 1 1 1 Negative Genetic
RPL42B YHR141C Ribosomal 60S subunit protein L42B genetic 1 1 1 Negative Genetic
TSA1 YML028W Thioredoxin peroxidase genetic 1 1 1 Synthetic Growth Defect
RPL19B YBL027W Ribosomal 60S subunit protein L19B genetic 1 1 1 Negative Genetic
NPL4 YBR170C Substrate-recruiting cofactor of the Cdc48p-Npl4p-Ufd1p segregase genetic 1 1 1 Negative Genetic
THR4 YCR053W Threonine synthase genetic 1 1 1 Negative Genetic
XRN1 YGL173C Evolutionarily-conserved 5'-3' exonuclease genetic 1 1 1 Negative Genetic
YGL235W YGL235W Putative protein of unknown function genetic 1 1 1 Negative Genetic
SIN3 YOL004W Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 1 1 1 Negative Genetic
RIF2 YLR453C Protein that binds to the Rap1p C-terminus genetic 1 1 1 Negative Genetic
SUR7 YML052W Plasma membrane protein, component of eisosomes genetic 1 1 1 Negative Genetic
VPS9 YML097C Guanine nucleotide exchange factor (GEF) and ubiquitin receptor genetic 1 1 1 Negative Genetic
VAC7 YNL054W Integral vacuolar membrane protein genetic 1 1 1 Negative Genetic
TPM1 YNL079C Major isoform of tropomyosin genetic 1 1 1 Negative Genetic
SLA2 YNL243W Adaptor protein that links actin to clathrin and endocytosis genetic 1 1 1 Negative Genetic
YPL039W YPL039W Putative protein of unknown function genetic 1 1 1 Negative Genetic
PEP4 YPL154C Vacuolar aspartyl protease (proteinase A) genetic 1 1 1 Negative Genetic
RVS161 YCR009C Amphiphysin-like lipid raft protein genetic 1 1 1 Synthetic Rescue
HKR1 YDR420W Mucin family member that functions as an osmosensor in the HOG pathway genetic 1 1 1 Negative Genetic
GTT1 YIR038C ER associated glutathione S-transferase physical 1 1 1 Two-hybrid
MID1 YNL291C Stretch-activated Ca2+-permeable cation channel genetic 1 1 1 Phenotypic Enhancement
GAB1 YLR459W Subunit of the glycosylphosphatidylinositol transamidase complex genetic 1 1 1 Negative Genetic
ATX1 YNL259C Cytosolic copper metallochaperone physical 1 1 1 Two-hybrid
ATX1 YNL259C Cytosolic copper metallochaperone genetic 1 1 1 Synthetic Growth Defect
HNM1 YGL077C Plasma membrane transporter for choline, ethanolamine, and carnitine physical 1 1 1 PCA
ERG7 YHR072W Lanosterol synthase genetic 1 1 1 Negative Genetic
ADE16 YLR028C Enzyme of 'de novo' purine biosynthesis genetic 1 1 1 Negative Genetic
FTR1 YER145C High affinity iron permease physical 1 1 1 PCA
FAS1 YKL182W Beta subunit of fatty acid synthetase physical 1 1 1 Two-hybrid
ALR2 YFL050C Probable Mg(2+) transporter genetic 1 1 1 Negative Genetic
FPS1 YLL043W Aquaglyceroporin, plasma membrane channel physical 1 1 1 PCA
DNF2 YDR093W Aminophospholipid translocase (flippase) physical 1 1 1 PCA
FMP45 YDL222C Integral membrane protein localized to mitochondria physical 1 1 1 PCA
HXT1 YHR094C Low-affinity glucose transporter of the major facilitator superfamily physical 1 1 1 PCA
ENA2 YDR039C P-type ATPase sodium pump physical 1 1 1 PCA
HSP30 YCR021C Negative regulator of the H(+)-ATPase Pma1p physical 1 1 1 PCA
ITR1 YDR497C Myo-inositol transporter physical 1 1 1 PCA
MEP3 YPR138C Ammonium permease of high capacity and low affinity physical 1 1 1 PCA
DYN3 YMR299C Dynein light intermediate chain (LIC) physical 1 1 1 PCA
EFR3 YMR212C Protein required for Stt4-containing PI kinase complex localization physical 1 1 1 PCA
KRE9 YJL174W Glycoprotein involved in cell wall beta-glucan assembly genetic 1 1 1 Synthetic Rescue
GRX2 YDR513W Cytoplasmic glutaredoxin genetic 1 1 1 Negative Genetic
GPI15 YNL038W Protein involved in the synthesis of GlcNAc-PI genetic 1 1 1 Negative Genetic
ERG12 YMR208W Mevalonate kinase genetic 1 1 1 Negative Genetic
EMC3 YKL207W Member of conserved ER transmembrane complex genetic 1 1 1 Negative Genetic
LNP1 YHR192W Lunapark family member involved in ER network formation physical 1 1 1 Two-hybrid