Standard name Systematic name Name description Description
PMT2 YAL023C Protein O-mannosyltransferase of the ER membrane Protein O-mannosyltransferase of the ER membrane; transfers mannose residues from dolichyl phosphate-D-mannose to protein serine/threonine residues; involved in ER quality control; functions as a heterodimer with Pmt2p but can also pair with Pmt5p; antifungal drug target; PMT2 has a paralog, PMT3, that arose from the whole genome duplication
Visualize the interactome of PMT2
Links to external databases:
SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)
G1(P) 24

CYCLoPs localization & abundance

WT1 WT2 WT3
Cort. Patches 0.058 NaN NaN
Cytoplasm 0.526 0.559 0.621
ER 0.404 0.390 0.078
Mito 0.053 0.084 0.128
Endosome NaN NaN 0.119
Vac/Vac Memb NaN NaN 0.064

GFP localization & abundance

GFP localization GFP abundance
ER 6510

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
PMT2 10 0 0 4 0

Enzyme information

Catalyzed reactions in Yeast8
r_0362 (dolichyl-phosphate-mannose--protein mannosyltransferase)

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
PMT1 YDL095W Protein O-mannosyltransferase of the ER membrane genetic 14 4 13 Dosage Rescue, Phenotypic Enhancement, Phenotypic Enhancement, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Phenotypic Enhancement, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Phenotypic Enhancement, Phenotypic Enhancement, Negative Genetic
PMT3 YOR321W Protein O-mannosyltransferase genetic 9 2 6 Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
PMT1 YDL095W Protein O-mannosyltransferase of the ER membrane physical 8 3 6 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Co-crystal Structure
ALG6 YOR002W ER-luminal alpha 1,3 glucosyltransferase genetic 7 2 5 Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
IRE1 YHR079C Serine-threonine kinase and endoribonuclease genetic 7 2 4 Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
ROT2 YBR229C Glucosidase II catalytic subunit genetic 7 2 4 Negative Genetic, Negative Genetic, Phenotypic Suppression, Phenotypic Suppression, Negative Genetic, Negative Genetic, Negative Genetic
GAS1 YMR307W Beta-1,3-glucanosyltransferase required for cell wall assembly genetic 6 1 5 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
PMT4 YJR143C Protein O-mannosyltransferase genetic 6 4 4 Phenotypic Enhancement, Synthetic Lethality, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
ILM1 YJR118C Protein of unknown function genetic 6 2 4 Negative Genetic, Negative Genetic, Phenotypic Suppression, Phenotypic Suppression, Negative Genetic, Negative Genetic
SEC66 YBR171W Non-essential subunit of Sec63 complex genetic 6 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
PMT6 YGR199W Protein O-mannosyltransferase genetic 6 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
CWH41 YGL027C Processing alpha glucosidase I genetic 6 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
LAS21 YJL062W Mannose-ethanolamine phosphotransferase genetic 6 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
RIC1 YLR039C Protein involved in retrograde transport to the cis-Golgi network genetic 5 2 4 Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic
HAC1 YFL031W Basic leucine zipper (bZIP) transcription factor (ATF/CREB1 homolog) genetic 5 2 4 Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
BCK1 YJL095W MAPKKK acting in the protein kinase C signaling pathway genetic 5 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
BST1 YFL025C GPI inositol deacylase of the endoplasmic reticulum (ER) genetic 5 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
LHS1 YKL073W Molecular chaperone of the endoplasmic reticulum lumen genetic 5 2 3 Positive Genetic, Positive Genetic, Phenotypic Suppression, Phenotypic Suppression, Positive Genetic
VPS9 YML097C Guanine nucleotide exchange factor (GEF) and ubiquitin receptor genetic 5 2 3 Negative Genetic, Phenotypic Suppression, Phenotypic Suppression, Negative Genetic, Negative Genetic
PER1 YCR044C Protein of the endoplasmic reticulum genetic 5 2 3 Negative Genetic, Negative Genetic, Phenotypic Suppression, Phenotypic Suppression, Negative Genetic
OST6 YML019W Subunit of the oligosaccharyltransferase complex of the ER lumen genetic 5 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
ALG3 YBL082C Dolichol-P-Man dependent alpha(1-3) mannosyltransferase genetic 5 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
GUP1 YGL084C Plasma membrane protein involved in remodeling GPI anchors genetic 5 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SLG1 YOR008C Sensor-transducer of the stress-activated PKC1-MPK1 kinase pathway genetic 4 3 4 Dosage Rescue, Synthetic Lethality, Negative Genetic, Negative Genetic
PKC1 YBL105C Protein serine/threonine kinase genetic 4 2 3 Dosage Rescue, Negative Genetic, Negative Genetic, Negative Genetic
PMA1 YGL008C Plasma membrane P2-type H+-ATPase genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
OST3 YOR085W Gamma subunit of the oligosaccharyltransferase complex of the ER lumen genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
VPS21 YOR089C Endosomal Rab family GTPase genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
UBX2 YML013W Bridging factor involved in ER-associated protein degradation (ERAD) genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SLT2 YHR030C Serine/threonine MAP kinase genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
PMR1 YGL167C High affinity Ca2+/Mn2+ P-type ATPase genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
CWH43 YCR017C GPI lipid remodelase genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
ICE2 YIL090W Integral ER membrane protein with type-III transmembrane domains genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
ERV25 YML012W Member of the p24 family involved in ER to Golgi transport genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
PMT7 YDR307W Putative protein mannosyltransferase similar to Pmt1p genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
DPM1 YPR183W Dolichol phosphate mannose (Dol-P-Man) synthase of ER membrane genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
GPI8 YDR331W Catalytic subunit of the ER membrane GPI transamidase complex genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
HSP82 YPL240C Hsp90 chaperone genetic 3 2 3 Synthetic Lethality, Synthetic Growth Defect, Synthetic Growth Defect
ECM33 YBR078W GPI-anchored protein involved in efficient glucose uptake genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
EMP24 YGL200C Component of the p24 complex genetic 3 2 2 Negative Genetic, Negative Genetic, Phenotypic Enhancement
MGA2 YIR033W ER membrane protein involved in regulation of OLE1 transcription genetic 3 2 2 Phenotypic Suppression, Phenotypic Suppression, Negative Genetic
GET2 YER083C Subunit of the GET complex genetic 3 2 2 Phenotypic Suppression, Phenotypic Suppression, Negative Genetic
ERD1 YDR414C Predicted membrane protein required for lumenal ER protein retention genetic 3 2 2 Phenotypic Suppression, Phenotypic Suppression, Negative Genetic
NBP2 YDR162C Protein involved in the HOG (high osmolarity glycerol) pathway genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
RGP1 YDR137W Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SCS7 YMR272C Sphingolipid alpha-hydroxylase genetic 3 1 2 Positive Genetic, Positive Genetic, Positive Genetic
RGD1 YBR260C GTPase-activating protein (RhoGAP) for Rho3p and Rho4p genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SEC59 YMR013C Dolichol kinase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
MON2 YNL297C Protein with a role in endocytosis and vacuole integrity genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
GAB1 YLR459W Subunit of the glycosylphosphatidylinositol transamidase complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
ANY1 YMR010W Protein involved in phospholipid flippase function genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
GPI17 YDR434W Transmembrane protein genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
ARV1 YLR242C Cortical ER protein genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
FPS1 YLL043W Aquaglyceroporin, plasma membrane channel genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
ENV9 YOR246C Conserved oxidoreductase involved in lipid droplet morphology genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
PGA3 YML125C Putative cytochrome b5 reductase, localized to the plasma membrane genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
CNB1 YKL190W Calcineurin B genetic 2 2 2 Synthetic Lethality, Negative Genetic
BEM1 YBR200W Protein containing SH3-domains genetic 2 1 2 Negative Genetic, Negative Genetic
ELP2 YGR200C Subunit of Elongator complex genetic 2 1 2 Negative Genetic, Negative Genetic
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
PHO23 YNL097C Component of the Rpd3L histone deacetylase complex genetic 2 1 2 Negative Genetic, Negative Genetic
DUO1 YGL061C Essential subunit of the Dam1 complex (aka DASH complex) genetic 2 1 2 Negative Genetic, Negative Genetic
KAR2 YJL034W ATPase involved in protein import into the ER genetic 2 1 2 Positive Genetic, Positive Genetic
PTC1 YDL006W Type 2C protein phosphatase (PP2C) genetic 2 1 2 Negative Genetic, Negative Genetic
WBP1 YEL002C Beta subunit of the oligosaccharyl transferase glycoprotein complex genetic 2 1 2 Positive Genetic, Positive Genetic
UBP6 YFR010W Ubiquitin-specific protease genetic 2 1 2 Negative Genetic, Negative Genetic
SEC72 YLR292C Non-essential subunit of Sec63 complex genetic 2 1 2 Negative Genetic, Negative Genetic
VPS17 YOR132W Subunit of the membrane-associated retromer complex genetic 2 1 2 Negative Genetic, Negative Genetic
VPS1 YKR001C Dynamin-like GTPase required for vacuolar sorting genetic 2 1 2 Negative Genetic, Negative Genetic
SLA1 YBL007C Cytoskeletal protein binding protein genetic 2 1 2 Negative Genetic, Negative Genetic
SAC7 YDR389W GTPase activating protein (GAP) for Rho1p genetic 2 1 2 Negative Genetic, Negative Genetic
TPM1 YNL079C Major isoform of tropomyosin genetic 2 1 2 Positive Genetic, Positive Genetic
YCK2 YNL154C Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform genetic 2 1 2 Negative Genetic, Negative Genetic
ERI1 YPL096C-A Endoplasmic reticulum membrane protein that binds and inhibits Ras2p genetic 2 1 2 Negative Genetic, Negative Genetic
MNN2 YBR015C Alpha-1,2-mannosyltransferase genetic 2 1 2 Negative Genetic, Negative Genetic
KRE1 YNL322C Cell wall glycoprotein involved in beta-glucan assembly genetic 2 1 2 Negative Genetic, Negative Genetic
ALG9 YNL219C Mannosyltransferase, involved in N-linked glycosylation genetic 2 1 2 Negative Genetic, Negative Genetic
EMP24 YGL200C Component of the p24 complex physical 2 2 1 Affinity Capture-Western, Affinity Capture-MS
ARC18 YLR370C Subunit of the ARP2/3 complex genetic 2 1 1 Phenotypic Suppression, Phenotypic Suppression
GLO3 YER122C ADP-ribosylation factor GTPase activating protein (ARF GAP) genetic 2 1 1 Phenotypic Suppression, Phenotypic Suppression
IPP1 YBR011C Cytoplasmic inorganic pyrophosphatase (PPase) genetic 2 1 1 Negative Genetic, Negative Genetic
ACK1 YDL203C Protein that functions in the cell wall integrity pathway genetic 2 1 1 Negative Genetic, Negative Genetic
FYV8 YGR196C Protein of unknown function genetic 2 1 1 Negative Genetic, Negative Genetic
GET3 YDL100C Guanine nucleotide exchange factor for Gpa1p genetic 2 1 1 Phenotypic Suppression, Phenotypic Suppression
GET1 YGL020C Subunit of the GET complex genetic 2 1 1 Phenotypic Suppression, Phenotypic Suppression
DOP1 YDR141C Protein involved in vesicular transport at trans-Golgi network (TGN) genetic 2 1 1 Negative Genetic, Negative Genetic
MEH1 YKR007W Subunit of the EGO/GSE complex genetic 2 1 1 Phenotypic Suppression, Phenotypic Suppression
CYS3 YAL012W Cystathionine gamma-lyase genetic 2 1 1 Phenotypic Suppression, Phenotypic Suppression
PEF1 YGR058W Penta-EF-hand protein genetic 2 1 1 Phenotypic Suppression, Phenotypic Suppression
GPI16 YHR188C Subunit of the glycosylphosphatidylinositol transamidase complex genetic 2 1 1 Negative Genetic, Negative Genetic
BRE5 YNR051C Ubiquitin protease cofactor genetic 2 1 1 Phenotypic Suppression, Phenotypic Suppression
ELO3 YLR372W Elongase genetic 2 1 1 Phenotypic Suppression, Phenotypic Suppression
PHO80 YOL001W Cyclin genetic 2 1 1 Phenotypic Suppression, Phenotypic Suppression
EMC5 YIL027C Member of conserved ER transmembrane complex genetic 2 1 1 Negative Genetic, Negative Genetic
TOH1 YJL171C GPI-anchored cell wall protein of unknown function genetic 2 1 1 Negative Genetic, Negative Genetic
VPS52 YDR484W Component of the GARP (Golgi-associated retrograde protein) complex genetic 2 1 1 Negative Genetic, Negative Genetic
SUR2 YDR297W Sphinganine C4-hydroxylase genetic 2 1 1 Positive Genetic, Positive Genetic
SIL1 YOL031C Nucleotide exchange factor for the ER lumenal Hsp70 chaperone Kar2p genetic 2 1 1 Positive Genetic, Positive Genetic
SKY1 YMR216C SR protein kinase (SRPK) genetic 2 1 1 Phenotypic Suppression, Phenotypic Suppression
VPS51 YKR020W Component of the GARP (Golgi-associated retrograde protein) complex genetic 2 1 1 Phenotypic Suppression, Phenotypic Suppression
SPT4 YGR063C Spt4p/5p (DSIF) transcription elongation factor complex subunit genetic 2 1 1 Phenotypic Suppression, Phenotypic Suppression
SPF1 YEL031W P-type ATPase, ion transporter of the ER membrane genetic 2 1 1 Phenotypic Suppression, Phenotypic Suppression
SEC22 YLR268W R-SNARE protein genetic 2 1 1 Phenotypic Suppression, Phenotypic Suppression
SRS2 YJL092W DNA helicase and DNA-dependent ATPase genetic 2 1 1 Dosage Lethality, Dosage Lethality
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes genetic 2 1 1 Dosage Lethality, Dosage Lethality
ERV14 YGL054C COPII-coated vesicle protein genetic 2 1 1 Phenotypic Suppression, Phenotypic Suppression
ERG2 YMR202W C-8 sterol isomerase genetic 2 1 1 Phenotypic Suppression, Phenotypic Suppression
GPI2 YPL076W Protein involved in the synthesis of GlcNAc-PI genetic 2 1 1 Negative Genetic, Negative Genetic
ERG4 YGL012W C-24(28) sterol reductase genetic 2 1 1 Negative Genetic, Negative Genetic
HLJ1 YMR161W Co-chaperone for Hsp40p genetic 2 1 1 Phenotypic Suppression, Phenotypic Suppression
ALG2 YGL065C Mannosyltransferase in the N-linked glycosylation pathway genetic 2 1 1 Negative Genetic, Negative Genetic
GPI11 YDR302W ER membrane protein involved in a late step of GPI anchor assembly genetic 2 1 1 Negative Genetic, Negative Genetic
SUM1 YDR310C Transcriptional repressor that regulates middle-sporulation genes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MED2 YDL005C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RAP1 YNL216W Essential DNA-binding transcription regulator that binds many loci regulation 1 1 1 DNA to cDNA expression microarray evidence
ABF1 YKL112W DNA binding protein with possible chromatin-reorganizing activity regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MED6 YHR058C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SPT3 YDR392W Subunit of the SAGA and SAGA-like transcriptional regulatory complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAP5 YIR018W Basic leucine zipper (bZIP) iron-sensing transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
PAT1 YCR077C Deadenylation-dependent mRNA-decapping factor physical 1 1 1 Affinity Capture-RNA
CDC48 YDL126C AAA ATPase with protein-unfoldase activity physical 1 1 1 Affinity Capture-MS
NPL3 YDR432W RNA-binding protein genetic 1 1 1 Synthetic Growth Defect
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 1 1 1 Negative Genetic
PEP1 YBL017C Type I transmembrane sorting receptor for multiple vacuolar hydrolases genetic 1 1 1 Negative Genetic
CDC11 YJR076C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Negative Genetic
ERO1 YML130C Thiol oxidase required for oxidative protein folding in the ER physical 1 1 1 Affinity Capture-MS
ERO1 YML130C Thiol oxidase required for oxidative protein folding in the ER genetic 1 1 1 Positive Genetic
ERP1 YAR002C-A Member of the p24 family involved in ER to Golgi transport physical 1 1 1 Affinity Capture-MS
ERP2 YAL007C Member of the p24 family involved in ER to Golgi transport physical 1 1 1 Affinity Capture-MS
ERV25 YML012W Member of the p24 family involved in ER to Golgi transport physical 1 1 1 Affinity Capture-MS
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
CMD1 YBR109C Calmodulin genetic 1 1 1 Negative Genetic
MNN10 YDR245W Subunit of a Golgi mannosyltransferase complex genetic 1 1 1 Negative Genetic
CDC13 YDL220C Single stranded DNA-binding protein found at TG1-3 telomere G-tails genetic 1 1 1 Synthetic Rescue
FAR7 YFR008W Protein involved in recovery from pheromone-induced cell cycle arrest genetic 1 1 1 Negative Genetic
HYP2 YEL034W Translation elongation factor eIF-5A genetic 1 1 1 Positive Genetic
PHO85 YPL031C Cyclin-dependent kinase genetic 1 1 1 Dosage Lethality
CAF20 YOR276W Phosphoprotein of the mRNA cap-binding complex physical 1 1 1 Affinity Capture-MS
CNA1 YLR433C Calcineurin A genetic 1 1 1 Negative Genetic
PDI1 YCL043C Protein disulfide isomerase physical 1 1 1 Affinity Capture-MS
HSP104 YLL026W Disaggregase physical 1 1 1 Affinity Capture-MS
PBR1 YNL181W Putative oxidoreductase genetic 1 1 1 Negative Genetic
ERG6 YML008C Delta(24)-sterol C-methyltransferase genetic 1 1 1 Negative Genetic
NUS1 YDL193W Forms dehydrodolichyl diphosphate synthase complex with RER2 or SRT1 genetic 1 1 1 Negative Genetic
LEM3 YNL323W Membrane protein of the plasma membrane and ER genetic 1 1 1 Negative Genetic
ARG1 YOL058W Arginosuccinate synthetase genetic 1 1 1 Synthetic Growth Defect
PMI40 YER003C Mannose-6-phosphate isomerase genetic 1 1 1 Negative Genetic
BIR1 YJR089W Subunit of chromosomal passenger complex (CPC) genetic 1 1 1 Positive Genetic
ARP1 YHR129C Actin-related protein of the dynactin complex genetic 1 1 1 Synthetic Lethality
CUP2 YGL166W Copper-binding transcription factor genetic 1 1 1 Negative Genetic
HCS1 YKL017C Hexameric DNA polymerase alpha-associated DNA helicase A genetic 1 1 1 Negative Genetic
MOB2 YFL034C-B Activator of Cbk1p kinase genetic 1 1 1 Negative Genetic
CET1 YPL228W RNA 5'-triphosphatase involved in mRNA 5' capping genetic 1 1 1 Positive Genetic
BFR1 YOR198C Component of mRNP complexes associated with polyribosomes physical 1 1 1 Affinity Capture-RNA
MPT5 YGL178W mRNA-binding protein of the PUF family physical 1 1 1 Affinity Capture-RNA
MID2 YLR332W O-glycosylated plasma membrane protein genetic 1 1 1 Dosage Rescue
MCA1 YOR197W Ca2+-dependent cysteine protease physical 1 1 1 Affinity Capture-MS
HRD1 YOL013C Ubiquitin-protein ligase involved in ER-associated degradation (ERAD) physical 1 1 1 Affinity Capture-MS
HRD1 YOL013C Ubiquitin-protein ligase involved in ER-associated degradation (ERAD) genetic 1 1 1 Phenotypic Enhancement
HOC1 YJR075W Alpha-1,6-mannosyltransferase genetic 1 1 1 Negative Genetic
MNN11 YJL183W Subunit of a Golgi mannosyltransferase complex genetic 1 1 1 Positive Genetic
PMT5 YDL093W Protein O-mannosyltransferase physical 1 1 1 Affinity Capture-Western
YCR043C YCR043C Putative protein of unknown function physical 1 1 1 Affinity Capture-MS
SKS1 YPL026C Putative serine/threonine protein kinase physical 1 1 1 Biochemical Activity
SHE2 YKL130C RNA-binding protein that binds specific mRNAs and interacts with She3p physical 1 1 1 Affinity Capture-RNA
RPN10 YHR200W Proteasome polyubiquitin receptor physical 1 1 1 Affinity Capture-MS
UIP3 YAR027W Putative integral membrane protein of unknown function physical 1 1 1 PCA
USA1 YML029W Scaffold subunit of the Hrd1p ubiquitin ligase physical 1 1 1 Affinity Capture-MS
YOS9 YDR057W ER quality-control lectin physical 1 1 1 Affinity Capture-MS
SRO9 YCL037C Cytoplasmic RNA-binding protein physical 1 1 1 Affinity Capture-RNA
SAC1 YKL212W Phosphatidylinositol phosphate phosphatase physical 1 1 1 Affinity Capture-MS
SAC1 YKL212W Phosphatidylinositol phosphate phosphatase genetic 1 1 1 Negative Genetic
SCS2 YER120W Integral ER membrane protein, regulates phospholipid metabolism physical 1 1 1 Affinity Capture-MS
PUF3 YLL013C Protein of the mitochondrial outer surface physical 1 1 1 Affinity Capture-RNA
SET4 YJL105W Chromatin-associated protein involved in control of stress response physical 1 1 1 Affinity Capture-MS
PSG1 YKL077W Protein that promotes the transport and maturation of Pma1 with Exp1 physical 1 1 1 Affinity Capture-MS
SND2 YLR065C Protein involved in SRP-independent targeting of substrates to the ER physical 1 1 1 Affinity Capture-MS
SND3 YBR106W Involved in SRP-independent protein targeting to the ER physical 1 1 1 Affinity Capture-MS
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p genetic 1 1 1 Negative Genetic
SUV3 YPL029W ATP-dependent RNA helicase genetic 1 1 1 Positive Genetic
RCR1 YBR005W Plasma membrane (PM) ubiquitin ligase-substrate adaptor genetic 1 1 1 Synthetic Rescue
YPT6 YLR262C Rab family GTPase genetic 1 1 1 Negative Genetic
YME1 YPR024W Catalytic subunit of i-AAA protease complex genetic 1 1 1 Positive Genetic
YKU70 YMR284W Subunit of the telomeric Ku complex (Yku70p-Yku80p) genetic 1 1 1 Negative Genetic
TEL2 YGR099W Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Positive Genetic
UBC11 YOR339C Ubiquitin-conjugating enzyme genetic 1 1 1 Positive Genetic
SKN7 YHR206W Nuclear response regulator and transcription factor genetic 1 1 1 Negative Genetic
SEC61 YLR378C Conserved ER protein translocation channel genetic 1 1 1 Negative Genetic
TRS65 YGR166W Component of transport protein particle (TRAPP) complex II genetic 1 1 1 Negative Genetic
VPS24 YKL041W One of four subunits of the ESCRT-III complex genetic 1 1 1 Negative Genetic
VPS27 YNR006W Endosomal protein that forms a complex with Hse1p genetic 1 1 1 Negative Genetic
PSD1 YNL169C Phosphatidylserine decarboxylase of the mitochondrial inner membrane genetic 1 1 1 Positive Genetic
VPS74 YDR372C Golgi PI4K effector, PtdIns4P sensor, and retention receptor genetic 1 1 1 Negative Genetic
TLG2 YOL018C Syntaxin-like t-SNARE genetic 1 1 1 Negative Genetic
RUD3 YOR216C Golgi matrix protein genetic 1 1 1 Negative Genetic
VPS38 YLR360W Part of a Vps34p phosphatidylinositol 3-kinase complex genetic 1 1 1 Negative Genetic
VPS30 YPL120W Subunit of phosphatidylinositol (PtdIns) 3-kinase complexes I and II genetic 1 1 1 Negative Genetic
VPS5 YOR069W Nexin-1 homolog genetic 1 1 1 Negative Genetic
RAD27 YKL113C 5' to 3' exonuclease, 5' flap endonuclease genetic 1 1 1 Positive Genetic
TGL1 YKL140W Steryl ester hydrolase genetic 1 1 1 Negative Genetic
SUR1 YPL057C Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit genetic 1 1 1 Positive Genetic
VPS55 YJR044C Late endosomal protein involved in late endosome to vacuole transport genetic 1 1 1 Negative Genetic
RTT107 YHR154W BRCA1 C-terminal domain protein needed for recovery from DNA damage genetic 1 1 1 Negative Genetic
RFT1 YBL020W Membrane protein required for translocation of Man5GlcNac2-PP-Dol genetic 1 1 1 Negative Genetic
RER2 YBR002C Forms the dehydrodolichyl diphosphate synthase (DDS) complex with NUS1 genetic 1 1 1 Negative Genetic
TAF5 YBR198C Subunit (90 kDa) of TFIID and SAGA complexes genetic 1 1 1 Negative Genetic
TAO3 YIL129C Component of the RAM signaling network genetic 1 1 1 Negative Genetic
RLP24 YLR009W Essential protein required for ribosomal large subunit biogenesis genetic 1 1 1 Negative Genetic
ROT1 YMR200W Molecular chaperone involved in protein folding in ER genetic 1 1 1 Negative Genetic
RPS3 YNL178W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
TPT1 YOL102C tRNA 2'-phosphotransferase that catalyzes final step in tRNA splicing genetic 1 1 1 Negative Genetic
SEC53 YFL045C Phosphomannomutase genetic 1 1 1 Negative Genetic
RPP2B YDR382W Ribosomal protein P2 beta genetic 1 1 1 Negative Genetic
TMN3 YER113C Protein with a role in cellular adhesion and filamentous growth genetic 1 1 1 Negative Genetic
RAD4 YER162C Damaged-DNA binding subunit of Nuclear Excision Repair Factor 2 genetic 1 1 1 Negative Genetic
YIL067C YIL067C Uncharacterized protein of unknown function genetic 1 1 1 Negative Genetic
YIR042C YIR042C Putative protein of unknown function genetic 1 1 1 Negative Genetic
SSP2 YOR242C Sporulation specific protein that localizes to the spore wall genetic 1 1 1 Negative Genetic
YBR196C-A YBR196C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
RSM28 YDR494W Mitochondrial ribosomal protein of the small subunit genetic 1 1 1 Negative Genetic
YDR524C-B YDR524C-B Putative protein of unknown function genetic 1 1 1 Negative Genetic
SNG1 YGR197C Protein involved in resistance to nitrosoguanidine and 6-azauracil genetic 1 1 1 Negative Genetic
TMH11 YJR085C Mitochondrial protein of unknown function genetic 1 1 1 Negative Genetic
ROM2 YLR371W Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p genetic 1 1 1 Negative Genetic
VAN1 YML115C Component of the mannan polymerase I genetic 1 1 1 Negative Genetic
VAC7 YNL054W Integral vacuolar membrane protein genetic 1 1 1 Negative Genetic
RPL20B YOR312C Ribosomal 60S subunit protein L20B genetic 1 1 1 Negative Genetic
RPS9A YPL081W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
AIM44 YPL158C Regulator of Cdc42p and Rho1p genetic 1 1 1 Positive Genetic
ALG1 YBR110W Mannosyltransferase genetic 1 1 1 Negative Genetic
CUE1 YMR264W Ubiquitin-binding protein genetic 1 1 1 Phenotypic Enhancement
IFA38 YBR159W Microsomal beta-keto-reductase physical 1 1 1 Affinity Capture-MS
MSS4 YDR208W Phosphatidylinositol-4-phosphate 5-kinase genetic 1 1 1 Negative Genetic
CSH1 YBR161W Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit genetic 1 1 1 Negative Genetic
GAA1 YLR088W Subunit of the GPI:protein transamidase complex genetic 1 1 1 Negative Genetic
DFM1 YDR411C Endoplasmic reticulum (ER) localized protein physical 1 1 1 Affinity Capture-MS
MLF3 YNL074C Serine-rich protein of unknown function physical 1 1 1 Affinity Capture-MS
HUR1 YGL168W Protein with a role in DNA repair genetic 1 1 1 Negative Genetic
COX10 YPL172C Heme A:farnesyltransferase genetic 1 1 1 Positive Genetic
GPI19 YDR437W Subunit of GPI-GlcNAc transferase involved in synthesis of GlcNAc-PI genetic 1 1 1 Negative Genetic
DER1 YBR201W ER membrane protein that promotes export of misfolded polypeptides genetic 1 1 1 Phenotypic Enhancement
ASI2 YNL159C Subunit of the inner nuclear membrane Asi ubiquitin ligase complex genetic 1 1 1 Negative Genetic
MPS3 YJL019W Nuclear envelope protein physical 1 1 1 Affinity Capture-MS
ERP4 YOR016C Member of the p24 family involved in ER to Golgi transport genetic 1 1 1 Negative Genetic
GPI13 YLL031C ER membrane localized phosphoryltransferase genetic 1 1 1 Negative Genetic
MTL1 YGR023W Putative plasma membrane sensor genetic 1 1 1 Dosage Rescue
OPI3 YJR073C Methylene-fatty-acyl-phospholipid synthase genetic 1 1 1 Negative Genetic
ECM4 YKR076W S-glutathionyl-(chloro)hydroquinone reductase (GS-HQR) genetic 1 1 1 Negative Genetic
MCH4 YOL119C Protein with similarity to mammalian monocarboxylate permeases genetic 1 1 1 Negative Genetic
GPI15 YNL038W Protein involved in the synthesis of GlcNAc-PI genetic 1 1 1 Negative Genetic
NHX1 YDR456W Na+/H+ and K+/H+ exchanger genetic 1 1 1 Negative Genetic
ALG8 YOR067C Glucosyl transferase genetic 1 1 1 Negative Genetic
HMS2 YJR147W Protein with similarity to heat shock transcription factors genetic 1 1 1 Negative Genetic