Standard name Systematic name Name description Description
SKS1 YPL026C Putative serine/threonine protein kinase Putative serine/threonine protein kinase; involved in the adaptation to low concentrations of glucose independent of the SNF3 regulated pathway; SKS1 has a paralog, VHS1, that arose from the whole genome duplication
Visualize the interactome of SKS1
Links to external databases:
SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)
S 74

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.994 0.983 1.0

GFP localization & abundance

GFP localization GFP abundance
cytoplasm 2810

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
SKS1 1 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
APS1 YLR170C Small subunit of the clathrin-associated adaptor complex AP-1 genetic 5 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
DEG1 YFL001W tRNA:pseudouridine synthase genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
VHC1 YBR235W Vacuolar membrane cation-chloride cotransporter (CCC) genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
UME6 YDR207C Rpd3L histone deacetylase complex subunit genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
FKH2 YNL068C Forkhead family transcription factor regulation 3 2 3 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments
MBA1 YBR185C Membrane-associated mitochondrial ribosome receptor genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
SNF3 YDL194W Plasma membrane low glucose sensor, regulates glucose transport genetic 3 2 2 Dosage Rescue, Synthetic Growth Defect, Dosage Rescue
FKH1 YIL131C Forkhead family transcription factor regulation 2 2 2 chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments
SEF1 YBL066C Putative transcription factor physical 2 2 2 Biochemical Activity, Affinity Capture-MS
UTR1 YJR049C ATP-NADH kinase physical 2 2 2 Biochemical Activity, Affinity Capture-MS
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 2 1 2 DNA to cDNA expression microarray evidence, DNA to cDNA expression microarray evidence
SKN7 YHR206W Nuclear response regulator and transcription factor regulation 2 1 2 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence
EAF1 YDR359C Component of the NuA4 histone acetyltransferase complex genetic 2 1 2 Positive Genetic, Positive Genetic
RSC2 YLR357W Component of the RSC chromatin remodeling complex genetic 2 1 2 Positive Genetic, Positive Genetic
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 2 1 2 Negative Genetic, Negative Genetic
DBF2 YGR092W Ser/Thr kinase involved in transcription and stress response genetic 2 1 2 Negative Genetic, Negative Genetic
AKR1 YDR264C Palmitoyl transferase involved in protein palmitoylation genetic 2 1 2 Negative Genetic, Negative Genetic
RIA1 YNL163C Cytoplasmic GTPase/eEF2-like factor involved in ribosomal biogenesis genetic 2 1 2 Negative Genetic, Negative Genetic
SGT2 YOR007C Glutamine-rich cytoplasmic cochaperone genetic 2 1 2 Negative Genetic, Negative Genetic
EUG1 YDR518W Protein disulfide isomerase of the endoplasmic reticulum lumen genetic 2 1 2 Positive Genetic, Positive Genetic
VPS41 YDR080W Subunit of the HOPS endocytic tethering complex genetic 2 1 2 Positive Genetic, Positive Genetic
YGL235W YGL235W Putative protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
VPS55 YJR044C Late endosomal protein involved in late endosome to vacuole transport genetic 2 1 2 Negative Genetic, Negative Genetic
YOR008C-A YOR008C-A Putative protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
OAF3 YKR064W Putative transcriptional repressor with Zn(2)-Cys(6) finger genetic 2 1 2 Negative Genetic, Negative Genetic
ASP3-3 YLR158C Cell-wall L-asparaginase II involved in asparagine catabolism genetic 2 1 2 Negative Genetic, Negative Genetic
RFX1 YLR176C Major transcriptional repressor of DNA-damage-regulated genes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
GCR1 YPL075W Transcriptional activator of genes involved in glycolysis regulation 1 1 1 DNA to cDNA expression microarray evidence
GCR2 YNL199C Transcriptional activator of genes involved in glycolysis regulation 1 1 1 DNA to cDNA expression microarray evidence
MSN2 YMR037C Stress-responsive transcriptional activator regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAP1 YML007W Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
NRG1 YDR043C Transcriptional repressor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SPT3 YDR392W Subunit of the SAGA and SAGA-like transcriptional regulatory complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SPT7 YBR081C Subunit of the SAGA transcriptional regulatory complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RPS31 YLR167W Fusion protein cleaved to yield ribosomal protein S31 and ubiquitin regulation 1 1 1 qualitative western immunoblotting evidence
UBI4 YLL039C Ubiquitin regulation 1 1 1 qualitative western immunoblotting evidence
RPL40A YIL148W Ubiquitin-ribosomal 60S subunit protein L40A fusion protein regulation 1 1 1 qualitative western immunoblotting evidence
RPL40B YKR094C Ubiquitin-ribosomal 60S subunit protein L40B fusion protein regulation 1 1 1 qualitative western immunoblotting evidence
MTW1 YAL034W-A Essential component of the MIND kinetochore complex physical 1 1 1 Biochemical Activity
PRP45 YAL032C Protein required for pre-mRNA splicing genetic 1 1 1 Negative Genetic
NUG1 YER006W GTPase that associates with nuclear 60S pre-ribosomes genetic 1 1 1 Negative Genetic
FRT2 YAL028W Tail-anchored ER membrane protein of unknown function physical 1 1 1 Biochemical Activity
KES1 YPL145C Sterol/phosphatidylinositol-4-phosphate (PI(4)P) exchanger genetic 1 1 1 Synthetic Lethality
GUS1 YGL245W Glutamyl-tRNA synthetase (GluRS) physical 1 1 1 Biochemical Activity
RPN5 YDL147W Subunit of the CSN and 26S proteasome lid complexes physical 1 1 1 Two-hybrid
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
ACC1 YNR016C Acetyl-CoA carboxylase, biotin containing enzyme physical 1 1 1 Affinity Capture-MS
CDC55 YGL190C Regulatory subunit B of protein phosphatase 2A (PP2A) genetic 1 1 1 Positive Genetic
ELP2 YGR200C Subunit of Elongator complex physical 1 1 1 Reconstituted Complex
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
KIN3 YAR018C Nonessential serine/threonine protein kinase genetic 1 1 1 Negative Genetic
HDA2 YDR295C Subunit of HDA1 histone deacetylase complex physical 1 1 1 Two-hybrid
MUM2 YBR057C Protein essential for meiotic DNA replication and sporulation genetic 1 1 1 Negative Genetic
MYO1 YHR023W Type II myosin heavy chain physical 1 1 1 Two-hybrid
GIN4 YDR507C Protein kinase involved in bud growth and assembly of the septin ring genetic 1 1 1 Dosage Growth Defect
PUB1 YNL016W Poly (A)+ RNA-binding protein physical 1 1 1 Affinity Capture-MS
RPB11 YOL005C RNA polymerase II subunit B12.5 genetic 1 1 1 Negative Genetic
OSH2 YDL019C Member of an oxysterol-binding protein family with seven members physical 1 1 1 Biochemical Activity
HEK2 YBL032W RNA binding protein involved in asymmetric localization of ASH1 mRNA physical 1 1 1 Affinity Capture-RNA
HYP2 YEL034W Translation elongation factor eIF-5A genetic 1 1 1 Positive Genetic
PHO85 YPL031C Cyclin-dependent kinase genetic 1 1 1 Dosage Lethality
CAF20 YOR276W Phosphoprotein of the mRNA cap-binding complex physical 1 1 1 Affinity Capture-RNA
GRR1 YJR090C F-box protein component of an SCF ubiquitin-ligase complex genetic 1 1 1 Dosage Rescue
OYE3 YPL171C Conserved NADPH oxidoreductase containing flavin mononucleotide (FMN) physical 1 1 1 Reconstituted Complex
ADK1 YDR226W Adenylate kinase, required for purine metabolism physical 1 1 1 Biochemical Activity
CLN1 YMR199W G1 cyclin involved in regulation of the cell cycle genetic 1 1 1 Negative Genetic
ERG10 YPL028W Acetyl-CoA C-acetyltransferase (acetoacetyl-CoA thiolase) physical 1 1 1 Affinity Capture-MS
LAF1 YMR102C Sterol-binding beta-propeller protein physical 1 1 1 Biochemical Activity
ELM1 YKL048C Serine/threonine protein kinase genetic 1 1 1 Dosage Growth Defect
CAT5 YOR125C Protein required for ubiquinone (Coenzyme Q) biosynthesis genetic 1 1 1 Negative Genetic
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 1 1 1 Positive Genetic
GLE1 YDL207W Cytoplasmic nucleoporin required for polyadenylated mRNA export genetic 1 1 1 Negative Genetic
NTF2 YER009W Nuclear envelope protein genetic 1 1 1 Positive Genetic
CDC15 YAR019C Hippo-like kinase of the Mitotic Exit Network physical 1 1 1 Biochemical Activity
EMI2 YDR516C Hexokinase expressed during growth with low glucose levels physical 1 1 1 Reconstituted Complex
RAS2 YNL098C GTP-binding protein genetic 1 1 1 Phenotypic Suppression
SGT1 YOR057W Cochaperone protein genetic 1 1 1 Negative Genetic
MIG1 YGL035C Transcription factor involved in glucose repression genetic 1 1 1 Negative Genetic
MDJ1 YFL016C Co-chaperone that stimulates HSP70 protein Ssc1p ATPase activity physical 1 1 1 Biochemical Activity
JJJ1 YNL227C Co-chaperone that stimulates the ATPase activity of Ssa1p physical 1 1 1 Biochemical Activity
NBP2 YDR162C Protein involved in the HOG (high osmolarity glycerol) pathway genetic 1 1 1 Negative Genetic
SKA1 YKL023W SKI complex-associated protein physical 1 1 1 Reconstituted Complex
GZF3 YJL110C GATA zinc finger protein physical 1 1 1 Two-hybrid
IPK1 YDR315C Inositol 1,3,4,5,6-pentakisphosphate 2-kinase genetic 1 1 1 Positive Genetic
HSP10 YOR020C Mitochondrial matrix co-chaperonin physical 1 1 1 Biochemical Activity
PKC1 YBL105C Protein serine/threonine kinase genetic 1 1 1 Negative Genetic
RFT1 YBL020W Membrane protein required for translocation of Man5GlcNac2-PP-Dol genetic 1 1 1 Negative Genetic
RSC30 YHR056C Component of the RSC chromatin remodeling complex physical 1 1 1 Biochemical Activity
RSC1 YGR056W Component of the RSC chromatin remodeling complex genetic 1 1 1 Negative Genetic
DAL81 YIR023W Positive regulator of genes in multiple nitrogen degradation pathways genetic 1 1 1 Negative Genetic
CBF1 YJR060W Basic helix-loop-helix (bHLH) protein genetic 1 1 1 Negative Genetic
RAD5 YLR032W DNA helicase/Ubiquitin ligase genetic 1 1 1 Positive Genetic
KAR2 YJL034W ATPase involved in protein import into the ER physical 1 1 1 Two-hybrid
MPT5 YGL178W mRNA-binding protein of the PUF family physical 1 1 1 Affinity Capture-RNA
GPR1 YDL035C Plasma membrane G protein coupled receptor (GPCR) genetic 1 1 1 Phenotypic Suppression
MGA1 YGR249W Protein similar to heat shock transcription factor physical 1 1 1 Biochemical Activity
BSD2 YBR290W Heavy metal ion homeostasis protein genetic 1 1 1 Negative Genetic
MNN11 YJL183W Subunit of a Golgi mannosyltransferase complex genetic 1 1 1 Positive Genetic
PMT2 YAL023C Protein O-mannosyltransferase of the ER membrane physical 1 1 1 Biochemical Activity
RIM20 YOR275C Protein involved in proteolytic activation of Rim101p genetic 1 1 1 Negative Genetic
ENT5 YDR153C Protein containing an N-terminal epsin-like domain genetic 1 1 1 Negative Genetic
AQR1 YNL065W Plasma membrane transporter of the major facilitator superfamily physical 1 1 1 Biochemical Activity
BOP3 YNL042W Protein of unknown function physical 1 1 1 Affinity Capture-MS
MTD1 YKR080W NAD-dependent 5,10-methylenetetrahydrafolate dehydrogenase physical 1 1 1 Reconstituted Complex
PLP1 YDR183W Protein that interacts with CCT (chaperonin containing TCP-1) complex physical 1 1 1 Biochemical Activity
NFS1 YCL017C Cysteine desulfurase involved in iron-sulfur cluster biogenesis physical 1 1 1 Affinity Capture-MS
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 1 1 1 Positive Genetic
NTH1 YDR001C Neutral trehalase, degrades trehalose physical 1 1 1 Biochemical Activity
SAS10 YDL153C Subunit of U3-containing Small Subunit (SSU) processome complex physical 1 1 1 Biochemical Activity
PFK26 YIL107C 6-phosphofructo-2-kinase physical 1 1 1 Biochemical Activity
OCA5 YHL029C Cytoplasmic protein required for replication of Brome mosaic virus genetic 1 1 1 Negative Genetic
IGD1 YFR017C Cytoplasmic protein that inhibits Gdb1p glycogen debranching activity physical 1 1 1 Biochemical Activity
AVT3 YKL146W Vacuolar transporter physical 1 1 1 Biochemical Activity
CMR3 YPR013C Putative zinc finger protein physical 1 1 1 Biochemical Activity
INP54 YOL065C Phosphatidylinositol 4,5-bisphosphate 5-phosphatase physical 1 1 1 Biochemical Activity
RCM1 YNL022C rRNA m5C methyltransferase physical 1 1 1 Biochemical Activity
VPS53 YJL029C Component of the GARP (Golgi-associated retrograde protein) complex physical 1 1 1 Biochemical Activity
VHS2 YIL135C Regulator of septin dynamics physical 1 1 1 Biochemical Activity
VHR2 YER064C Non-essential nuclear protein physical 1 1 1 Biochemical Activity
SOL2 YCR073W-A Protein with a possible role in tRNA export physical 1 1 1 Biochemical Activity
YML096W YML096W Putative protein with similarity to asparagine synthetases physical 1 1 1 Biochemical Activity
SPS100 YHR139C Protein required for spore wall maturation physical 1 1 1 Biochemical Activity
SPE1 YKL184W Ornithine decarboxylase physical 1 1 1 Biochemical Activity
YPL088W YPL088W Putative aryl alcohol dehydrogenase physical 1 1 1 Biochemical Activity
STE3 YKL178C Receptor for a factor pheromone physical 1 1 1 Biochemical Activity
VMA5 YKL080W Subunit C of the V1 peripheral membrane domain of V-ATPase physical 1 1 1 Biochemical Activity
TRP3 YKL211C Indole-3-glycerol-phosphate synthase physical 1 1 1 Reconstituted Complex
UBA1 YKL210W Ubiquitin activating enzyme (E1) physical 1 1 1 Reconstituted Complex
YCR016W YCR016W Putative protein of unknown function physical 1 1 1 Reconstituted Complex
SPC72 YAL047C Gamma-tubulin small complex (gamma-TuSC) receptor physical 1 1 1 Two-hybrid
STE50 YCL032W Adaptor protein for various signaling pathways physical 1 1 1 Two-hybrid
TAF1 YGR274C TFIID subunit, involved in RNA pol II transcription initiation physical 1 1 1 Two-hybrid
STB2 YMR053C Protein that interacts with Sin3p in a two-hybrid assay physical 1 1 1 Two-hybrid
TYE7 YOR344C Serine-rich protein that contains a bHLH DNA binding motif physical 1 1 1 Two-hybrid
YPD1 YDL235C Osmotic stress-responsive phosphorelay intermediate sensor protein genetic 1 1 1 Positive Genetic
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p) genetic 1 1 1 Negative Genetic
SKY1 YMR216C SR protein kinase (SRPK) genetic 1 1 1 Positive Genetic
TFB1 YDR311W Subunit of TFIIH and nucleotide excision repair factor 3 complexes genetic 1 1 1 Positive Genetic
YGR210C YGR210C Putative protein of unknown function genetic 1 1 1 Positive Genetic
SSC1 YJR045C Hsp70 family ATPase genetic 1 1 1 Negative Genetic
YDR524C-B YDR524C-B Putative protein of unknown function genetic 1 1 1 Negative Genetic
UBR1 YGR184C E3 ubiquitin ligase (N-recognin) genetic 1 1 1 Negative Genetic
TUL1 YKL034W Subunit of the DSC ubiquitin ligase complex genetic 1 1 1 Negative Genetic
YPT7 YML001W Rab family GTPase genetic 1 1 1 Negative Genetic
SWS2 YNL081C Putative mitochondrial ribosomal protein of the small subunit genetic 1 1 1 Negative Genetic
SMT1 YJL147C Translational repressor of the mitochondrial ATP6/8 mRNA genetic 1 1 1 Negative Genetic
VAM3 YOR106W Syntaxin-like vacuolar t-SNARE genetic 1 1 1 Negative Genetic
COQ8 YGL119W ATPase required for ubiquinone biosynthesis and respiratory growth physical 1 1 1 Biochemical Activity
PAU22 YPL282C Protein of unknown function physical 1 1 1 Biochemical Activity
PMT6 YGR199W Protein O-mannosyltransferase physical 1 1 1 Biochemical Activity
PUF2 YPR042C PUF family mRNA-binding protein physical 1 1 1 Affinity Capture-RNA
HXT2 YMR011W High-affinity glucose transporter of the major facilitator superfamily genetic 1 1 1 Phenotypic Suppression
RER2 YBR002C Forms the dehydrodolichyl diphosphate synthase (DDS) complex with NUS1 genetic 1 1 1 Negative Genetic
OPI3 YJR073C Methylene-fatty-acyl-phospholipid synthase genetic 1 1 1 Negative Genetic
MDL2 YPL270W Mitochondrial inner membrane half-type ABC transporter genetic 1 1 1 Negative Genetic
MNE1 YOR350C Protein involved in splicing Group I aI5-beta intron from COX1 mRNA genetic 1 1 1 Negative Genetic