HDA3 |
YPR179C |
Subunit of HDA1 histone deacetylase complex |
physical |
6 |
4 |
4 |
Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS, Two-hybrid |
HDA1 |
YNL021W |
Catalytic subunit of class II HDA1 histone deacetylase complex |
physical |
6 |
3 |
4 |
Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
NUF2 |
YOL069W |
Component of the kinetochore-associated Ndc80 complex |
physical |
5 |
1 |
3 |
Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid |
EAF3 |
YPR023C |
Component of the Rpd3S histone deacetylase complex |
genetic |
5 |
2 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic |
PHO23 |
YNL097C |
Component of the Rpd3L histone deacetylase complex |
genetic |
5 |
2 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Rescue |
SAP30 |
YMR263W |
Component of Rpd3L histone deacetylase complex |
genetic |
5 |
2 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Rescue |
SIN3 |
YOL004W |
Component of both the Rpd3S and Rpd3L histone deacetylase complexes |
genetic |
5 |
2 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic |
SPC24 |
YMR117C |
Component of the kinetochore-associated Ndc80 complex |
physical |
4 |
1 |
3 |
Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid |
HTZ1 |
YOL012C |
Histone variant H2AZ |
genetic |
4 |
2 |
2 |
Synthetic Rescue, Synthetic Rescue, Synthetic Rescue, Phenotypic Suppression |
EPL1 |
YFL024C |
Subunit of NuA4, an essential histone H4/H2A acetyltransferase complex |
genetic |
4 |
1 |
2 |
Synthetic Rescue, Synthetic Rescue, Synthetic Rescue, Synthetic Rescue |
RPD3 |
YNL330C |
Histone deacetylase, component of both the Rpd3S and Rpd3L complexes |
genetic |
4 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect |
MSH2 |
YOL090W |
Protein that binds to DNA mismatches |
physical |
3 |
2 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Two-hybrid |
ERG3 |
YLR056W |
C-5 sterol desaturase |
genetic |
3 |
2 |
3 |
Synthetic Rescue, Negative Genetic, Negative Genetic |
ARP4 |
YJL081C |
Nuclear actin-related protein involved in chromatin remodeling |
genetic |
3 |
2 |
2 |
Synthetic Rescue, Synthetic Rescue, Negative Genetic |
ARC18 |
YLR370C |
Subunit of the ARP2/3 complex |
genetic |
3 |
2 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic |
RIM13 |
YMR154C |
Calpain-like cysteine protease |
genetic |
3 |
2 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic |
RIM20 |
YOR275C |
Protein involved in proteolytic activation of Rim101p |
genetic |
3 |
2 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic |
RIM8 |
YGL045W |
Protein involved in proteolytic activation of Rim101p |
genetic |
3 |
2 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic |
STP22 |
YCL008C |
Component of the ESCRT-I complex |
genetic |
3 |
2 |
2 |
Synthetic Lethality, Synthetic Lethality, Synthetic Rescue |
SWI6 |
YLR182W |
Transcription cofactor |
genetic |
3 |
2 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic |
VPS25 |
YJR102C |
Component of the ESCRT-II complex |
genetic |
3 |
2 |
2 |
Synthetic Lethality, Synthetic Lethality, Synthetic Rescue |
ARP6 |
YLR085C |
Actin-related protein that binds nucleosomes |
genetic |
3 |
2 |
2 |
Synthetic Rescue, Synthetic Rescue, Positive Genetic |
NNF1 |
YJR112W |
Essential component of the outer kinetochore MIND complex |
physical |
3 |
1 |
2 |
Two-hybrid, Two-hybrid, Two-hybrid |
ACE2 |
YLR131C |
Transcription factor required for septum destruction after cytokinesis |
physical |
3 |
1 |
2 |
Two-hybrid, Two-hybrid, Two-hybrid |
ELP3 |
YPL086C |
Subunit of Elongator complex |
genetic |
3 |
1 |
2 |
Synthetic Rescue, Synthetic Rescue, Synthetic Rescue |
HDA1 |
YNL021W |
Catalytic subunit of class II HDA1 histone deacetylase complex |
genetic |
2 |
2 |
2 |
Synthetic Rescue, Positive Genetic |
RCO1 |
YMR075W |
Essential component of the Rpd3S histone deacetylase complex |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
RRP6 |
YOR001W |
Nuclear exosome exonuclease component |
genetic |
2 |
2 |
2 |
Phenotypic Enhancement, Phenotypic Suppression |
RPN10 |
YHR200W |
Proteasome polyubiquitin receptor |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
RPN4 |
YDL020C |
Transcription factor that stimulates expression of proteasome genes |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Synthetic Rescue |
MAD1 |
YGL086W |
Coiled-coil protein involved in spindle-assembly checkpoint |
physical |
2 |
1 |
2 |
Two-hybrid, Two-hybrid |
NUM1 |
YDR150W |
Protein required for nuclear migration |
physical |
2 |
1 |
2 |
Two-hybrid, Two-hybrid |
SPT10 |
YJL127C |
Histone H3 acetylase with a role in transcriptional regulation |
genetic |
2 |
1 |
2 |
Synthetic Rescue, Synthetic Rescue |
ESA1 |
YOR244W |
Catalytic subunit of the histone acetyltransferase complex (NuA4) |
genetic |
2 |
1 |
1 |
Synthetic Rescue, Synthetic Rescue |
EAF1 |
YDR359C |
Component of the NuA4 histone acetyltransferase complex |
genetic |
2 |
1 |
1 |
Synthetic Rescue, Synthetic Rescue |
ELP2 |
YGR200C |
Subunit of Elongator complex |
genetic |
2 |
1 |
1 |
Synthetic Rescue, Synthetic Rescue |
DYN1 |
YKR054C |
Cytoplasmic heavy chain dynein |
physical |
2 |
1 |
1 |
Two-hybrid, Two-hybrid |
RAD50 |
YNL250W |
Subunit of MRX complex with Mre11p and Xrs2p |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
SSB1 |
YDL229W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
2 |
1 |
1 |
Affinity Capture-MS, Affinity Capture-MS |
SPC72 |
YAL047C |
Gamma-tubulin small complex (gamma-TuSC) receptor |
physical |
2 |
1 |
1 |
Two-hybrid, Two-hybrid |
LAM4 |
YHR080C |
Sterol-binding protein that localizes to puncta in the cortical ER |
physical |
2 |
1 |
1 |
Two-hybrid, Two-hybrid |
STB2 |
YMR053C |
Protein that interacts with Sin3p in a two-hybrid assay |
physical |
2 |
1 |
1 |
Two-hybrid, Two-hybrid |
NIP100 |
YPL174C |
Large subunit of the dynactin complex |
physical |
2 |
1 |
1 |
Two-hybrid, Two-hybrid |
YAF9 |
YNL107W |
Subunit of NuA4 histone H4 acetyltransferase and SWR1 complexes |
genetic |
2 |
1 |
1 |
Synthetic Rescue, Synthetic Rescue |
HHT1 |
YBR010W |
Histone H3 |
genetic |
2 |
1 |
1 |
Synthetic Rescue, Synthetic Rescue |
HFI1 |
YPL254W |
Adaptor protein required for structural integrity of the SAGA complex |
genetic |
2 |
1 |
1 |
Synthetic Rescue, Synthetic Rescue |
IKI3 |
YLR384C |
Subunit of Elongator complex |
genetic |
2 |
1 |
1 |
Synthetic Rescue, Synthetic Rescue |
SPT20 |
YOL148C |
Subunit of the SAGA transcriptional regulatory complex |
genetic |
2 |
1 |
1 |
Synthetic Rescue, Synthetic Rescue |
SPT7 |
YBR081C |
Subunit of the SAGA transcriptional regulatory complex |
genetic |
2 |
1 |
1 |
Synthetic Rescue, Synthetic Rescue |
SWC4 |
YGR002C |
Component of the Swr1p complex that incorporates Htz1p into chromatin |
genetic |
2 |
1 |
1 |
Synthetic Rescue, Synthetic Rescue |
SWC5 |
YBR231C |
Component of the SWR1 complex |
genetic |
2 |
1 |
1 |
Synthetic Rescue, Synthetic Rescue |
SWR1 |
YDR334W |
Swi2/Snf2-related ATPase |
genetic |
2 |
1 |
1 |
Synthetic Rescue, Synthetic Rescue |
VPS71 |
YML041C |
Nucleosome-binding component of the SWR1 complex |
genetic |
2 |
1 |
1 |
Synthetic Rescue, Synthetic Rescue |
VPS72 |
YDR485C |
Htz1p-binding component of the SWR1 complex |
genetic |
2 |
1 |
1 |
Synthetic Rescue, Synthetic Rescue |
YNG2 |
YHR090C |
Subunit of NuA4, an essential histone acetyltransferase complex |
genetic |
2 |
1 |
1 |
Synthetic Rescue, Synthetic Rescue |
HMO1 |
YDR174W |
Chromatin associated high mobility group (HMG) family member |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
ISM1 |
YPL040C |
Mitochondrial isoleucyl-tRNA synthetase |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
MGA2 |
YIR033W |
ER membrane protein involved in regulation of OLE1 transcription |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
MHR1 |
YDR296W |
Mitochondrial ribosomal protein of the large subunit |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
MON2 |
YNL297C |
Protein with a role in endocytosis and vacuole integrity |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
PML39 |
YML107C |
Protein required for nuclear retention of unspliced pre-mRNAs |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
PPR1 |
YLR014C |
Zinc finger transcription factor |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
PTC1 |
YDL006W |
Type 2C protein phosphatase (PP2C) |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
RCY1 |
YJL204C |
F-box protein involved in recycling endocytosed proteins |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
RIM101 |
YHL027W |
Cys2His2 zinc-finger transcriptional repressor |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
RIM21 |
YNL294C |
pH sensor molecule, component of the RIM101 pathway |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
RPA34 |
YJL148W |
RNA polymerase I subunit A34.5 |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
RSC1 |
YGR056W |
Component of the RSC chromatin remodeling complex |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
RSC2 |
YLR357W |
Component of the RSC chromatin remodeling complex |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
SNF8 |
YPL002C |
Component of the ESCRT-II complex |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
SPT21 |
YMR179W |
Protein with a role in transcriptional silencing |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
VPS36 |
YLR417W |
Component of the ESCRT-II complex |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
SET3 |
YKR029C |
Defining member of the SET3 histone deacetylase complex |
genetic |
2 |
1 |
1 |
Synthetic Rescue, Synthetic Rescue |
ARP8 |
YOR141C |
Nuclear actin-related protein involved in chromatin remodeling |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
GCN5 |
YGR252W |
Catalytic subunit of ADA and SAGA histone acetyltransferase complexes |
genetic |
2 |
1 |
1 |
Synthetic Rescue, Synthetic Rescue |
DIA4 |
YHR011W |
Probable mitochondrial seryl-tRNA synthetase |
physical |
2 |
1 |
1 |
Two-hybrid, Two-hybrid |
GET2 |
YER083C |
Subunit of the GET complex |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
ACS2 |
YLR153C |
Acetyl-coA synthetase isoform |
genetic |
2 |
1 |
1 |
Synthetic Rescue, Synthetic Rescue |
FHL1 |
YPR104C |
Regulator of ribosomal protein (RP) transcription |
genetic |
2 |
1 |
1 |
Synthetic Rescue, Synthetic Rescue |
ELP6 |
YMR312W |
Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex |
genetic |
2 |
1 |
1 |
Synthetic Rescue, Synthetic Rescue |
ELP4 |
YPL101W |
Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex |
genetic |
2 |
1 |
1 |
Synthetic Rescue, Synthetic Rescue |
BRE5 |
YNR051C |
Ubiquitin protease cofactor |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
COY1 |
YKL179C |
Golgi membrane protein with similarity to mammalian CASP |
physical |
2 |
1 |
1 |
Two-hybrid, Two-hybrid |
CDC50 |
YCR094W |
Endosomal protein that interacts with phospholipid flippase Drs2p |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
DFG16 |
YOR030W |
Probable multiple transmembrane protein |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
CCW12 |
YLR110C |
Cell wall mannoprotein |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
DPL1 |
YDR294C |
Dihydrosphingosine phosphate lyase |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
ABF1 |
YKL112W |
DNA binding protein with possible chromatin-reorganizing activity |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
CTR9 |
YOL145C |
Component of the Paf1p complex involved in transcription elongation |
physical |
1 |
1 |
1 |
Two-hybrid |
CTF19 |
YPL018W |
Outer kinetochore protein, needed for accurate chromosome segregation |
physical |
1 |
1 |
1 |
Two-hybrid |
CKB1 |
YGL019W |
Beta regulatory subunit of casein kinase 2 (CK2) |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
BRE1 |
YDL074C |
E3 ubiquitin ligase |
physical |
1 |
1 |
1 |
Two-hybrid |
FRT2 |
YAL028W |
Tail-anchored ER membrane protein of unknown function |
physical |
1 |
1 |
1 |
Two-hybrid |
ARL1 |
YBR164C |
Soluble GTPase with a role in regulation of membrane traffic |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC48 |
YDL126C |
AAA ATPase with protein-unfoldase activity |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CDC48 |
YDL126C |
AAA ATPase with protein-unfoldase activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
DST1 |
YGL043W |
General transcription elongation factor TFIIS |
genetic |
1 |
1 |
1 |
Negative Genetic |
ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
genetic |
1 |
1 |
1 |
Negative Genetic |
CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
ATG14 |
YBR128C |
Autophagy-specific subunit of phosphatidylinositol 3-kinase complex I |
physical |
1 |
1 |
1 |
Two-hybrid |
APL3 |
YBL037W |
Alpha-adaptin |
physical |
1 |
1 |
1 |
Two-hybrid |
ARC15 |
YIL062C |
Subunit of the ARP2/3 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARC35 |
YNR035C |
Subunit of the ARP2/3 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARD1 |
YHR013C |
Subunit of protein N-terminal acetyltransferase NatA |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
BET3 |
YKR068C |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC24 |
YAL041W |
Guanine nucleotide exchange factor (GEF) for Cdc42p |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC28 |
YBR160W |
Cyclin-dependent kinase (CDK) catalytic subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC10 |
YCR002C |
Component of the septin ring, required for cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC11 |
YJR076C |
Component of the septin ring that is required for cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC3 |
YLR314C |
Component of the septin ring that is required for cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
BNI1 |
YNL271C |
Formin |
physical |
1 |
1 |
1 |
Two-hybrid |
CEG1 |
YGL130W |
Guanylyltransferase involved in mRNA 5' capping |
genetic |
1 |
1 |
1 |
Negative Genetic |
CKS1 |
YBR135W |
Cyclin-dependent protein kinase regulatory subunit and adaptor |
genetic |
1 |
1 |
1 |
Negative Genetic |
DNA2 |
YHR164C |
ATP-dependent 5'-flap endonuclease and DNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
EMG1 |
YLR186W |
Methyltransferase for rRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
EXO84 |
YBR102C |
Exocyst subunit with dual roles in exocytosis and spliceosome assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
BDF2 |
YDL070W |
Protein involved in transcription initiation |
genetic |
1 |
1 |
1 |
Negative Genetic |
DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
DPB4 |
YDR121W |
Subunit of DNA pol epsilon and of ISW2 chromatin accessibility complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
END3 |
YNL084C |
EH domain-containing protein involved in endocytosis |
physical |
1 |
1 |
1 |
Two-hybrid |
COG3 |
YER157W |
Essential component of the conserved oligomeric Golgi complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ADA2 |
YDR448W |
Transcription coactivator |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
CCM1 |
YGR150C |
Mitochondrial 15S rRNA-binding protein |
physical |
1 |
1 |
1 |
Two-hybrid |
HDA3 |
YPR179C |
Subunit of HDA1 histone deacetylase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
RAD50 |
YNL250W |
Subunit of MRX complex with Mre11p and Xrs2p |
physical |
1 |
1 |
1 |
Two-hybrid |
SHP1 |
YBL058W |
UBX domain-containing substrate adaptor for Cdc48p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
IME2 |
YJL106W |
Serine/threonine protein kinase involved in activation of meiosis |
physical |
1 |
1 |
1 |
Biochemical Activity |
YCK2 |
YNL154C |
Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform |
physical |
1 |
1 |
1 |
Biochemical Activity |
HSK3 |
YKL138C-A |
Essential subunit of the Dam1 complex (aka DASH complex) |
physical |
1 |
1 |
1 |
Two-hybrid |
KIN3 |
YAR018C |
Nonessential serine/threonine protein kinase |
physical |
1 |
1 |
1 |
Two-hybrid |
MUM2 |
YBR057C |
Protein essential for meiotic DNA replication and sporulation |
physical |
1 |
1 |
1 |
Two-hybrid |
SWC3 |
YAL011W |
Protein of unknown function |
physical |
1 |
1 |
1 |
Two-hybrid |
NOT3 |
YIL038C |
Component of the CCR4-NOT core complex, involved in mRNA decapping |
physical |
1 |
1 |
1 |
Two-hybrid |
SEC10 |
YLR166C |
Essential 100kDa subunit of the exocyst complex |
physical |
1 |
1 |
1 |
Two-hybrid |
VPS20 |
YMR077C |
Myristoylated subunit of the ESCRT-III complex |
physical |
1 |
1 |
1 |
Two-hybrid |
SPP381 |
YBR152W |
mRNA splicing factor, component of U4/U6.U5 tri-snRNP |
physical |
1 |
1 |
1 |
Two-hybrid |
NHP10 |
YDL002C |
Non-essential INO80 chromatin remodeling complex subunit |
physical |
1 |
1 |
1 |
Two-hybrid |
NHP10 |
YDL002C |
Non-essential INO80 chromatin remodeling complex subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPC19 |
YDR201W |
Essential subunit of the Dam1 complex (aka DASH complex) |
physical |
1 |
1 |
1 |
Two-hybrid |
IVY1 |
YDR229W |
Phospholipid-binding protein that interacts with both Ypt7p and Vps33p |
physical |
1 |
1 |
1 |
Two-hybrid |
HDA2 |
YDR295C |
Subunit of HDA1 histone deacetylase complex |
physical |
1 |
1 |
1 |
Two-hybrid |
SHE9 |
YDR393W |
Protein required for normal mitochondrial morphology |
physical |
1 |
1 |
1 |
Two-hybrid |
SPC25 |
YER018C |
Component of the kinetochore-associated Ndc80 complex |
physical |
1 |
1 |
1 |
Two-hybrid |
TSC11 |
YER093C |
Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p) |
physical |
1 |
1 |
1 |
Two-hybrid |
TSC11 |
YER093C |
Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
PGD1 |
YGL025C |
Subunit of the RNA polymerase II mediator complex |
physical |
1 |
1 |
1 |
Two-hybrid |
SEC9 |
YGR009C |
t-SNARE protein required for secretory vesicle-plasma membrane fusion |
physical |
1 |
1 |
1 |
Two-hybrid |
SPR3 |
YGR059W |
Sporulation-specific homolog of the CDC3/10/11/12 family of genes |
physical |
1 |
1 |
1 |
Two-hybrid |
NNF2 |
YGR089W |
Protein that exhibits physical and genetic interactions with Rpb8p |
physical |
1 |
1 |
1 |
Two-hybrid |
YGR130C |
YGR130C |
Component of the eisosome with unknown function |
physical |
1 |
1 |
1 |
Two-hybrid |
YAP1802 |
YGR241C |
Protein of the AP180 family, involved in clathrin cage assembly |
physical |
1 |
1 |
1 |
Two-hybrid |
YTA7 |
YGR270W |
Chromatin-binding ATPase that regulates histone gene expression |
physical |
1 |
1 |
1 |
Two-hybrid |
SKN7 |
YHR206W |
Nuclear response regulator and transcription factor |
physical |
1 |
1 |
1 |
Two-hybrid |
MPS3 |
YJL019W |
Nuclear envelope protein |
physical |
1 |
1 |
1 |
Two-hybrid |
VPS53 |
YJL029C |
Component of the GARP (Golgi-associated retrograde protein) complex |
physical |
1 |
1 |
1 |
Two-hybrid |
VPS53 |
YJL029C |
Component of the GARP (Golgi-associated retrograde protein) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SNX4 |
YJL036W |
Sorting nexin |
physical |
1 |
1 |
1 |
Two-hybrid |
NET1 |
YJL076W |
Core subunit of the RENT complex |
physical |
1 |
1 |
1 |
Two-hybrid |
YJL113W |
YJL113W |
Retrotransposon TYA Gag and TYB Pol genes |
physical |
1 |
1 |
1 |
Two-hybrid |
SET2 |
YJL168C |
Histone methyltransferase with a role in transcriptional elongation |
physical |
1 |
1 |
1 |
Two-hybrid |
SET2 |
YJL168C |
Histone methyltransferase with a role in transcriptional elongation |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
SWE1 |
YJL187C |
Protein kinase that regulates the G2/M transition |
physical |
1 |
1 |
1 |
Two-hybrid |
MPP10 |
YJR002W |
Component of the SSU processome and 90S preribosome |
physical |
1 |
1 |
1 |
Two-hybrid |
REC107 |
YJR021C |
Protein involved in early stages of meiotic recombination |
physical |
1 |
1 |
1 |
Two-hybrid |
SGM1 |
YJR134C |
Protein of unknown function |
physical |
1 |
1 |
1 |
Two-hybrid |
SPC42 |
YKL042W |
Central plaque component of spindle pole body (SPB) |
physical |
1 |
1 |
1 |
Two-hybrid |
STB6 |
YKL072W |
Protein that binds Sin3p in a two-hybrid assay |
physical |
1 |
1 |
1 |
Two-hybrid |
LHS1 |
YKL073W |
Molecular chaperone of the endoplasmic reticulum lumen |
physical |
1 |
1 |
1 |
Two-hybrid |
RSM22 |
YKL155C |
Mitochondrial ribosomal protein of the small subunit |
physical |
1 |
1 |
1 |
Two-hybrid |
SNF7 |
YLR025W |
One of four subunits of the ESCRT-III complex |
physical |
1 |
1 |
1 |
Two-hybrid |
YLR031W |
YLR031W |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Two-hybrid |
REA1 |
YLR106C |
Huge dynein-related AAA-type ATPase (midasin) |
physical |
1 |
1 |
1 |
Two-hybrid |
MMR1 |
YLR190W |
Phosphorylated protein of the mitochondrial outer membrane |
physical |
1 |
1 |
1 |
Two-hybrid |
YAP1 |
YML007W |
Basic leucine zipper (bZIP) transcription factor |
physical |
1 |
1 |
1 |
Two-hybrid |
RNA1 |
YMR235C |
GTPase activating protein (GAP) for Gsp1p |
physical |
1 |
1 |
1 |
Two-hybrid |
RNA1 |
YMR235C |
GTPase activating protein (GAP) for Gsp1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
MET4 |
YNL103W |
Leucine-zipper transcriptional activator |
physical |
1 |
1 |
1 |
Two-hybrid |
SGO1 |
YOR073W |
Component of the spindle checkpoint |
physical |
1 |
1 |
1 |
Two-hybrid |
RBL2 |
YOR265W |
Protein involved in microtubule morphogenesis |
physical |
1 |
1 |
1 |
Two-hybrid |
SNF2 |
YOR290C |
Catalytic subunit of the SWI/SNF chromatin remodeling complex |
physical |
1 |
1 |
1 |
Two-hybrid |
SKS1 |
YPL026C |
Putative serine/threonine protein kinase |
physical |
1 |
1 |
1 |
Two-hybrid |
SVL3 |
YPL032C |
Protein of unknown function |
physical |
1 |
1 |
1 |
Two-hybrid |
SPC29 |
YPL124W |
Inner plaque spindle pole body (SPB) component |
physical |
1 |
1 |
1 |
Two-hybrid |
YPL216W |
YPL216W |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Two-hybrid |
MCM16 |
YPR046W |
Component of the Ctf19 complex and the COMA subcomplex |
physical |
1 |
1 |
1 |
Two-hybrid |
SPC105 |
YGL093W |
Subunit of a kinetochore-microtubule binding complex |
physical |
1 |
1 |
1 |
Two-hybrid |
KOG1 |
YHR186C |
Subunit of TORC1 |
physical |
1 |
1 |
1 |
Two-hybrid |
SMY1 |
YKL079W |
Kinesin-like myosin passenger-protein |
physical |
1 |
1 |
1 |
Two-hybrid |
SEG2 |
YKL105C |
Eisosome component |
physical |
1 |
1 |
1 |
Two-hybrid |
NDL1 |
YLR254C |
Homolog of nuclear distribution factor NudE |
physical |
1 |
1 |
1 |
Two-hybrid |
JNM1 |
YMR294W |
Component of the yeast dynactin complex |
physical |
1 |
1 |
1 |
Two-hybrid |
YAF9 |
YNL107W |
Subunit of NuA4 histone H4 acetyltransferase and SWR1 complexes |
physical |
1 |
1 |
1 |
Two-hybrid |
SLA2 |
YNL243W |
Adaptor protein that links actin to clathrin and endocytosis |
physical |
1 |
1 |
1 |
Two-hybrid |
RPT5 |
YOR117W |
ATPase of the 19S regulatory particle of the 26S proteasome |
physical |
1 |
1 |
1 |
Two-hybrid |
TYE7 |
YOR344C |
Serine-rich protein that contains a bHLH DNA binding motif |
physical |
1 |
1 |
1 |
Two-hybrid |
NOP53 |
YPL146C |
Nucleolar protein |
physical |
1 |
1 |
1 |
Two-hybrid |
PUF3 |
YLL013C |
Protein of the mitochondrial outer surface |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
PUB1 |
YNL016W |
Poly (A)+ RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PUB1 |
YNL016W |
Poly (A)+ RNA-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
HTA1 |
YDR225W |
Histone H2A |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
HSP82 |
YPL240C |
Hsp90 chaperone |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
HSC82 |
YMR186W |
Cytoplasmic chaperone of the Hsp90 family |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YNG1 |
YOR064C |
Subunit of the NuA3 histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
SLX8 |
YER116C |
Subunit of Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
NPT1 |
YOR209C |
Nicotinate phosphoribosyltransferase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
RXT2 |
YBR095C |
Component of the histone deacetylase Rpd3L complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
THP2 |
YHR167W |
Subunit of the THO and TREX complexes |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
SDS3 |
YIL084C |
Component of the Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
LGE1 |
YPL055C |
Protein involved in histone H2B ubiquitination |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
UBP6 |
YFR010W |
Ubiquitin-specific protease |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
SNF4 |
YGL115W |
Activating gamma subunit of the AMP-activated Snf1p kinase complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
SOH1 |
YGL127C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
SAM37 |
YMR060C |
Component of the Sorting and Assembly Machinery (SAM) complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
SCS7 |
YMR272C |
Sphingolipid alpha-hydroxylase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
RTF1 |
YGL244W |
Subunit of RNAPII-associated chromatin remodeling Paf1 complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
LST7 |
YGR057C |
Subunit of the Lst4p-Lst7p GTPase activating protein complex for Gtr2p |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
HIS7 |
YBR248C |
Imidazole glycerol phosphate synthase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
SPT4 |
YGR063C |
Spt4p/5p (DSIF) transcription elongation factor complex subunit |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
PAF1 |
YBR279W |
Component of the Paf1p complex involved in transcription elongation |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
PAC10 |
YGR078C |
Part of the heteromeric co-chaperone GimC/prefoldin complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
URE2 |
YNL229C |
Nitrogen catabolite repression transcriptional regulator |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
PRS3 |
YHL011C |
5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
SNT1 |
YCR033W |
Set3C histone deacetylase scaffold |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
SRB2 |
YHR041C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
PAT1 |
YCR077C |
Deadenylation-dependent mRNA-decapping factor |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
SRB8 |
YCR081W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
HIS6 |
YIL020C |
Enzyme that catalyzes the fourth step in the histidine pathway |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
SLX5 |
YDL013W |
Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
HOS4 |
YIL112W |
Subunit of the Set3 complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
IST3 |
YIR005W |
Component of the U2 snRNP |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
LSM1 |
YJL124C |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
THP1 |
YOL072W |
Nuclear pore-associated protein |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
PAP2 |
YOL115W |
Non-canonical poly(A) polymerase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
RPB4 |
YJL140W |
RNA polymerase II subunit B32 |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
SAC3 |
YDR159W |
mRNA export factor |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
PFD1 |
YJL179W |
Subunit of heterohexameric prefoldin |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
WHI2 |
YOR043W |
Negative regulator of TORC1 in response to limiting leucine |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
SSN3 |
YPL042C |
Component of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
SDC1 |
YDR469W |
Subunit of the COMPASS (Set1C) complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
ISA1 |
YLL027W |
Protein required for maturation of mitochondrial [4Fe-4S] proteins |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
YKE2 |
YLR200W |
Subunit of the heterohexameric Gim/prefoldin protein complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
MED1 |
YPR070W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
RIF2 |
YLR453C |
Protein that binds to the Rap1p C-terminus |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
TAF1 |
YGR274C |
TFIID subunit, involved in RNA pol II transcription initiation |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
PDC2 |
YDR081C |
Transcription factor for thiamine-regulated genes |
genetic |
1 |
1 |
1 |
Positive Genetic |
MOB2 |
YFL034C-B |
Activator of Cbk1p kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
SHE1 |
YBL031W |
Mitotic spindle protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
MON1 |
YGL124C |
Subunit of a heterodimeric guanine nucleotide exchange factor (GEF) |
genetic |
1 |
1 |
1 |
Positive Genetic |
YIA6 |
YIL006W |
Mitochondrial NAD+ transporter |
genetic |
1 |
1 |
1 |
Positive Genetic |
MNN11 |
YJL183W |
Subunit of a Golgi mannosyltransferase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
MIR1 |
YJR077C |
Mitochondrial phosphate carrier |
genetic |
1 |
1 |
1 |
Positive Genetic |
YRA2 |
YKL214C |
Member of the REF (RNA and export factor binding proteins) family |
genetic |
1 |
1 |
1 |
Positive Genetic |
MKT1 |
YNL085W |
Protein similar to nucleases that forms a complex with Pbp1p |
genetic |
1 |
1 |
1 |
Positive Genetic |
VAM3 |
YOR106W |
Syntaxin-like vacuolar t-SNARE |
genetic |
1 |
1 |
1 |
Positive Genetic |
SRO7 |
YPR032W |
Effector of Rab GTPase Sec4p |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPB5 |
YBR154C |
RNA polymerase subunit ABC27 |
genetic |
1 |
1 |
1 |
Negative Genetic |
MED8 |
YBR193C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
TAF5 |
YBR198C |
Subunit (90 kDa) of TFIID and SAGA complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
MCM7 |
YBR202W |
Component of the Mcm2-7 hexameric helicase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
TRS20 |
YBR254C |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
1 |
1 |
1 |
Negative Genetic |
KIN28 |
YDL108W |
Ser/Thr protein kinase and subunit of TFIIK, a TFIIH subassembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPO21 |
YDL140C |
RNA polymerase II largest subunit B220 |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPN11 |
YFR004W |
Metalloprotease subunit of 19S regulatory particle |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPT6 |
YGL048C |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
SLD3 |
YGL113W |
Protein involved in the initiation of DNA replication |
genetic |
1 |
1 |
1 |
Negative Genetic |
SKI6 |
YGR195W |
Exosome non-catalytic core component |
genetic |
1 |
1 |
1 |
Negative Genetic |
ZPR1 |
YGR211W |
Essential protein with two zinc fingers |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPN1 |
YHR027C |
Non-ATPase base subunit of the 19S RP of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
ORC6 |
YHR118C |
Subunit of the origin recognition complex (ORC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
RHO3 |
YIL118W |
Non-essential small GTPase of the Rho/Rac family of Ras-like proteins |
genetic |
1 |
1 |
1 |
Negative Genetic |
MTR4 |
YJL050W |
RNA duplex-sensing translocase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRP21 |
YJL203W |
Subunit of the SF3a splicing factor complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
POL31 |
YJR006W |
Subunit of DNA polymerase delta (polymerase III) |
genetic |
1 |
1 |
1 |
Negative Genetic |
TAH11 |
YJR046W |
DNA replication licensing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
RAM2 |
YKL019W |
Alpha subunit of farnesyltransferase and geranylgeranyltransferase-I |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPT1 |
YKL145W |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
ORC3 |
YLL004W |
Subunit of the origin recognition complex (ORC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SSL1 |
YLR005W |
Subunit of the core form of RNA polymerase transcription factor TFIIH |
genetic |
1 |
1 |
1 |
Negative Genetic |
RGR1 |
YLR071C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
NMT1 |
YLR195C |
N-myristoyl transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
UTP13 |
YLR222C |
Nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
TAF11 |
YML015C |
TFIID subunit (40 kDa) |
genetic |
1 |
1 |
1 |
Negative Genetic |
ORC1 |
YML065W |
Largest subunit of the origin recognition complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
POB3 |
YML069W |
Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
TAF13 |
YML098W |
TFIID subunit (19 kDa) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC65 |
YML105C |
Subunit of the signal recognition particle (SRP) |
genetic |
1 |
1 |
1 |
Negative Genetic |
TAF4 |
YMR005W |
TFIID subunit (48 kDa) |
genetic |
1 |
1 |
1 |
Negative Genetic |
VTI1 |
YMR197C |
Protein involved in cis-Golgi membrane traffic |
genetic |
1 |
1 |
1 |
Negative Genetic |
LCB1 |
YMR296C |
Component of serine palmitoyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRE6 |
YOL038W |
Alpha 4 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
PFY1 |
YOR122C |
Profilin |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPB2 |
YOR151C |
RNA polymerase II second largest subunit B150 |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPT4 |
YOR259C |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPA190 |
YOR341W |
RNA polymerase I largest subunit A190 |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC8 |
YPR055W |
Essential 121 kDa subunit of the exocyst complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS8A |
YBL072C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
YBL081W |
YBL081W |
Non-essential protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
MNN2 |
YBR015C |
Alpha-1,2-mannosyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
TPS1 |
YBR126C |
Synthase subunit of trehalose-6-P synthase/phosphatase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
MTC4 |
YBR255W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
SGF29 |
YCL010C |
Component of the HAT/Core module of the SAGA, SLIK, and ADA complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
RVS161 |
YCR009C |
Amphiphysin-like lipid raft protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
THR4 |
YCR053W |
Threonine synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL35B |
YDL136W |
Ribosomal 60S subunit protein L35B |
genetic |
1 |
1 |
1 |
Negative Genetic |
IES1 |
YFL013C |
Subunit of the INO80 chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
HXK2 |
YGL253W |
Hexokinase isoenzyme 2 |
genetic |
1 |
1 |
1 |
Negative Genetic |
SMI1 |
YGR229C |
Protein involved in the regulation of cell wall synthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS29 |
YHR012W |
Subunit of the membrane-associated retromer complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS35 |
YJL154C |
Endosomal subunit of membrane-associated retromer complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
TOF2 |
YKR010C |
Protein required for rDNA silencing and mitotic rDNA condensation |
genetic |
1 |
1 |
1 |
Negative Genetic |
YKR015C |
YKR015C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
IRS4 |
YKR019C |
EH domain-containing protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
SIS2 |
YKR072C |
Negative regulatory subunit of protein phosphatase 1 (Ppz1p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS13 |
YLL040C |
Lipid transport protein involved in prospore membrane morphogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
SRN2 |
YLR119W |
Component of the ESCRT-I complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PSP2 |
YML017W |
Asn rich cytoplasmic protein that contains RGG motifs |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS1B |
YML063W |
Ribosomal protein of the small (40S) subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS9 |
YML097C |
Guanine nucleotide exchange factor (GEF) and ubiquitin receptor |
genetic |
1 |
1 |
1 |
Negative Genetic |
YML108W |
YML108W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
MSC1 |
YML128C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
MAC1 |
YMR021C |
Copper-sensing transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS27 |
YNR006W |
Endosomal protein that forms a complex with Hse1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
TLG2 |
YOL018C |
Syntaxin-like t-SNARE |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS5 |
YOR069W |
Nexin-1 homolog |
genetic |
1 |
1 |
1 |
Negative Genetic |
SGF11 |
YPL047W |
Integral subunit of SAGA histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
YAR1 |
YPL239W |
Nucleocytoplasmic shuttling assembly chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
MDM36 |
YPR083W |
Mitochondrial protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
MAY24 |
YPR153W |
Peripheral ER membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS4 |
YPR173C |
AAA-ATPase involved in multivesicular body (MVB) protein sorting |
genetic |
1 |
1 |
1 |
Negative Genetic |
HHO1 |
YPL127C |
Histone H1, linker histone with roles in meiosis and sporulation |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
ILV1 |
YER086W |
Threonine deaminase, catalyzes first step in isoleucine biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
SGV1 |
YPR161C |
Cyclin (Bur2p)-dependent protein kinase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
AFG2 |
YLR397C |
ATPase of the CDC48/PAS1/SEC18 (AAA) family, forms a hexameric complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
GIM3 |
YNL153C |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
DEP1 |
YAL013W |
Component of the Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
CTI6 |
YPL181W |
Component of the Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
BET5 |
YML077W |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC13 |
YDL220C |
Single stranded DNA-binding protein found at TG1-3 telomere G-tails |
genetic |
1 |
1 |
1 |
Negative Genetic |
GSF2 |
YML048W |
Endoplasmic reticulum (ER) localized integral membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
DUN1 |
YDL101C |
Cell-cycle checkpoint S/T protein kinase |
genetic |
1 |
1 |
1 |
Dosage Lethality |
ERG27 |
YLR100W |
3-keto sterol reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
DYN2 |
YDR424C |
Cytoplasmic light chain dynein, microtubule motor protein |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
CDC20 |
YGL116W |
Activator of anaphase-promoting complex/cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
ETP1 |
YHL010C |
Protein of unknown function required for growth on ethanol |
physical |
1 |
1 |
1 |
Two-hybrid |
GYP5 |
YPL249C |
GTPase-activating protein (GAP) for yeast Rab family members |
physical |
1 |
1 |
1 |
Two-hybrid |
DNL4 |
YOR005C |
DNA ligase required for nonhomologous end-joining (NHEJ) |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
ARE1 |
YCR048W |
Acyl-CoA:sterol acyltransferase |
physical |
1 |
1 |
1 |
Two-hybrid |
ATE1 |
YGL017W |
Arginyl-tRNA-protein transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
DPB11 |
YJL090C |
DNA replication initiation protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
FAL1 |
YDR021W |
Nucleolar protein required for maturation of 18S rRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
EAP1 |
YKL204W |
eIF4E-associated protein, competes with eIF4G for binding to eIF4E |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
ERG11 |
YHR007C |
Lanosterol 14-alpha-demethylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
DAD2 |
YKR083C |
Essential subunit of the Dam1 complex (aka DASH complex) |
physical |
1 |
1 |
1 |
Two-hybrid |
BUD27 |
YFL023W |
Unconventional prefoldin protein involved in translation initiation |
physical |
1 |
1 |
1 |
Two-hybrid |
ATG1 |
YGL180W |
Protein serine/threonine kinase |
physical |
1 |
1 |
1 |
Two-hybrid |
FAR3 |
YMR052W |
Protein of unknown function |
physical |
1 |
1 |
1 |
Two-hybrid |
GZF3 |
YJL110C |
GATA zinc finger protein |
physical |
1 |
1 |
1 |
Two-hybrid |
COG2 |
YGR120C |
Essential component of the conserved oligomeric Golgi complex |
physical |
1 |
1 |
1 |
Two-hybrid |
CAK1 |
YFL029C |
Cyclin-dependent kinase-activating kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
FMP16 |
YDR070C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
APC11 |
YDL008W |
Catalytic core subunit, Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
CBF1 |
YJR060W |
Basic helix-loop-helix (bHLH) protein |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
ALF1 |
YNL148C |
Alpha-tubulin folding protein |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
CLB5 |
YPR120C |
B-type cyclin involved in DNA replication during S phase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
CTK2 |
YJL006C |
Beta subunit of C-terminal domain kinase I (CTDK-I) |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
ELO2 |
YCR034W |
Fatty acid elongase, involved in sphingolipid biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
BBP1 |
YPL255W |
Protein required for the spindle pole body (SPB) duplication |
physical |
1 |
1 |
1 |
Two-hybrid |
GOS1 |
YHL031C |
v-SNARE protein involved in Golgi transport |
genetic |
1 |
1 |
1 |
Negative Genetic |
ENT2 |
YLR206W |
Epsin-like protein required for endocytosis and actin patch assembly |
physical |
1 |
1 |
1 |
Two-hybrid |
CPR7 |
YJR032W |
Peptidyl-prolyl cis-trans isomerase (cyclophilin) |
genetic |
1 |
1 |
1 |
Negative Genetic |
DID2 |
YKR035W-A |
Class E protein of the vacuolar protein-sorting (Vps) pathway |
physical |
1 |
1 |
1 |
Two-hybrid |
ARL3 |
YPL051W |
ARF-like small GTPase of the RAS superfamily |
genetic |
1 |
1 |
1 |
Negative Genetic |
EAF6 |
YJR082C |
Subunit of the NuA4 acetyltransferase complex |
physical |
1 |
1 |
1 |
Two-hybrid |
DPM1 |
YPR183W |
Dolichol phosphate mannose (Dol-P-Man) synthase of ER membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
GTA1 |
YEL043W |
Protein of unknown function |
physical |
1 |
1 |
1 |
Two-hybrid |
FMP27 |
YLR454W |
Protein with structural similarity to lipid transport protein Vps13p |
physical |
1 |
1 |
1 |
Two-hybrid |
BTT1 |
YDR252W |
Heterotrimeric nascent polypeptide-associated complex beta3 subunit |
physical |
1 |
1 |
1 |
Two-hybrid |
ERP3 |
YDL018C |
Protein with similarity to Emp24p and Erv25p |
physical |
1 |
1 |
1 |
Two-hybrid |
CHO2 |
YGR157W |
Phosphatidylethanolamine methyltransferase (PEMT) |
genetic |
1 |
1 |
1 |
Negative Genetic |
FRT1 |
YOR324C |
Tail-anchored ER membrane protein of unknown function |
physical |
1 |
1 |
1 |
Two-hybrid |
ARR1 |
YPR199C |
Transcriptional activator of the basic leucine zipper (bZIP) family |
physical |
1 |
1 |
1 |
Two-hybrid |
CHM7 |
YJL049W |
Yeast homolog of human CHMP7, localizes to the endoplasmic reticulum |
physical |
1 |
1 |
1 |
Two-hybrid |
ENB1 |
YOL158C |
Ferric enterobactin transmembrane transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
APQ12 |
YIL040W |
Nuclear envelope/ER integral membrane protein |
genetic |
1 |
1 |
1 |
Synthetic Rescue |