Standard name Systematic name Name description Description
SNF7 YLR025W One of four subunits of the ESCRT-III complex One of four subunits of the ESCRT-III complex; involved in the sorting of transmembrane proteins into the multivesicular body (MVB) pathway; recruited from the cytoplasm to endosomal membranes; ESCRT-III stands for endosomal sorting complex required for transport III
Visualize the interactome of SNF7
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Bud NaN NaN 0.143
Cort. Patches NaN NaN 0.095
Endosome NaN NaN 0.095
Mito NaN NaN 0.333
Nucleolus NaN NaN 0.095
Peroxisome NaN NaN 0.381
SpindlePole NaN NaN 0.333

GFP localization & abundance

GFP localization GFP abundance
endosome 3270

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
SNF7 2 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
BRO1 YPL084W Cytoplasmic class E vacuolar protein sorting (VPS) factor physical 12 5 7 Two-hybrid, Two-hybrid, Affinity Capture-Western, PCA, Two-hybrid, Affinity Capture-Western, Two-hybrid, Affinity Capture-Western, Reconstituted Complex, Co-localization, Reconstituted Complex, Affinity Capture-Western
VPS4 YPR173C AAA-ATPase involved in multivesicular body (MVB) protein sorting physical 11 5 10 Affinity Capture-MS, Two-hybrid, Two-hybrid, Affinity Capture-MS, Two-hybrid, Affinity Capture-Western, Two-hybrid, Affinity Capture-Western, Affinity Capture-MS, Reconstituted Complex, PCA
VPS24 YKL041W One of four subunits of the ESCRT-III complex physical 11 5 9 Two-hybrid, Affinity Capture-MS, PCA, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western
VPS20 YMR077C Myristoylated subunit of the ESCRT-III complex physical 9 4 9 Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Two-hybrid, Affinity Capture-Western, Two-hybrid, Reconstituted Complex, PCA, Affinity Capture-Western
SNF7 YLR025W One of four subunits of the ESCRT-III complex physical 8 6 7 Two-hybrid, PCA, Affinity Capture-Western, FRET, PCA, Affinity Capture-Western, Reconstituted Complex, Co-fractionation
RIM20 YOR275C Protein involved in proteolytic activation of Rim101p physical 7 3 5 Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western
DOA4 YDR069C Ubiquitin hydrolase physical 6 4 5 Two-hybrid, PCA, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, PCA
DID4 YKL002W Class E Vps protein of the ESCRT-III complex physical 6 3 5 Affinity Capture-Western, PCA, Reconstituted Complex, PCA, Affinity Capture-Western, Affinity Capture-Western
RIM101 YHL027W Cys2His2 zinc-finger transcriptional repressor genetic 5 4 4 Phenotypic Suppression, Phenotypic Suppression, Synthetic Growth Defect, Dosage Rescue, Synthetic Rescue
CHM7 YJL049W Yeast homolog of human CHMP7, localizes to the endoplasmic reticulum physical 5 4 4 Two-hybrid, Two-hybrid, Reconstituted Complex, PCA, Affinity Capture-MS
VTA1 YLR181C Multivesicular body (MVB) protein physical 4 4 4 Two-hybrid, Affinity Capture-Western, PCA, Reconstituted Complex
VPS60 YDR486C Protein involved in late endosome to vacuole transport physical 4 3 4 PCA, Two-hybrid, Two-hybrid, Affinity Capture-Western
DID2 YKR035W-A Class E protein of the vacuolar protein-sorting (Vps) pathway physical 4 2 3 PCA, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western
RIM13 YMR154C Calpain-like cysteine protease physical 3 3 3 Two-hybrid, Affinity Capture-Western, Reconstituted Complex
YGR122W YGR122W Protein that may be involved in pH regulation physical 3 2 3 Two-hybrid, Two-hybrid, Reconstituted Complex
NRG1 YDR043C Transcriptional repressor genetic 3 1 3 Synthetic Rescue, Synthetic Rescue, Synthetic Rescue
IST1 YNL265C Protein with positive role in the multivesicular body sorting pathway physical 3 2 2 Co-localization, Affinity Capture-Western, Affinity Capture-Western
ELM1 YKL048C Serine/threonine protein kinase genetic 3 2 2 Synthetic Growth Defect, Synthetic Growth Defect, Dosage Growth Defect
ATG17 YLR423C Scaffold protein responsible for phagophore assembly site organization physical 3 2 1 PCA, Reconstituted Complex, Reconstituted Complex
DOA4 YDR069C Ubiquitin hydrolase genetic 2 2 2 Synthetic Rescue, Phenotypic Suppression
SNX41 YDR425W Sorting nexin genetic 2 2 2 Synthetic Rescue, Phenotypic Enhancement
DID4 YKL002W Class E Vps protein of the ESCRT-III complex genetic 2 2 2 Phenotypic Enhancement, Synthetic Growth Defect
ATG8 YBL078C Ub-like protein physical 2 2 2 Co-localization, Affinity Capture-MS
MPS3 YJL019W Nuclear envelope protein physical 2 2 2 Two-hybrid, Affinity Capture-MS
RCF1 YML030W Cytochrome c oxidase subunit physical 2 2 2 Affinity Capture-MS, Two-hybrid
VPS20 YMR077C Myristoylated subunit of the ESCRT-III complex genetic 2 2 1 Dosage Rescue, Phenotypic Suppression
NYV1 YLR093C v-SNARE component of the vacuolar SNARE complex genetic 2 2 1 Dosage Growth Defect, Synthetic Rescue
HEH2 YDR458C Inner nuclear membrane (INM) protein physical 2 2 1 Reconstituted Complex, PCA
PMC1 YGL006W Vacuolar Ca2+ ATPase involved in depleting cytosol of Ca2+ ions genetic 2 2 1 Dosage Rescue, Synthetic Growth Defect
HDA3 YPR179C Subunit of HDA1 histone deacetylase complex genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
NOT3 YIL038C Component of the CCR4-NOT core complex, involved in mRNA decapping physical 2 1 1 Two-hybrid, Two-hybrid
TYE7 YOR344C Serine-rich protein that contains a bHLH DNA binding motif physical 2 1 1 Two-hybrid, Two-hybrid
NNF1 YJR112W Essential component of the outer kinetochore MIND complex physical 2 1 1 Two-hybrid, Two-hybrid
YAP6 YDR259C Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ABF1 YKL112W DNA binding protein with possible chromatin-reorganizing activity regulation 1 1 1 chromatin immunoprecipitation-chip evidence
UME6 YDR207C Rpd3L histone deacetylase complex subunit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
PAF1 YBR279W Component of the Paf1p complex involved in transcription elongation regulation 1 1 1 quantitative reverse transcription polymerase chain reaction evidence
CTR9 YOL145C Component of the Paf1p complex involved in transcription elongation genetic 1 1 1 Synthetic Lethality
CTF19 YPL018W Outer kinetochore protein, needed for accurate chromosome segregation physical 1 1 1 Two-hybrid
DSN1 YIR010W Essential component of the outer kinetochore MIND complex genetic 1 1 1 Dosage Rescue
PAF1 YBR279W Component of the Paf1p complex involved in transcription elongation genetic 1 1 1 Synthetic Lethality
CKA2 YOR061W Alpha' catalytic subunit of casein kinase 2 (CK2) genetic 1 1 1 Dosage Growth Defect
GON7 YJL184W Component of the EKC/KEOPS protein complex physical 1 1 1 Two-hybrid
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 1 1 1 Synthetic Haploinsufficiency
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
RTT10 YPL183C WD40 domain-containing protein involved in endosomal recycling genetic 1 1 1 Phenotypic Enhancement
ATG14 YBR128C Autophagy-specific subunit of phosphatidylinositol 3-kinase complex I physical 1 1 1 Affinity Capture-MS
BET2 YPR176C Beta subunit of Type II geranylgeranyltransferase genetic 1 1 1 Negative Genetic
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit physical 1 1 1 Affinity Capture-MS
CDC10 YCR002C Component of the septin ring, required for cytokinesis genetic 1 1 1 Synthetic Rescue
CDC3 YLR314C Component of the septin ring that is required for cytokinesis physical 1 1 1 Two-hybrid
IPI3 YNL182C Component of the Rix1 complex and pre-replicative complexes (pre-RCs) physical 1 1 1 Two-hybrid
COX4 YGL187C Subunit IV of cytochrome c oxidase physical 1 1 1 Affinity Capture-MS
DYN1 YKR054C Cytoplasmic heavy chain dynein physical 1 1 1 Two-hybrid
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
IST1 YNL265C Protein with positive role in the multivesicular body sorting pathway genetic 1 1 1 Synthetic Growth Defect
ECM29 YHL030W Scaffold protein physical 1 1 1 Affinity Capture-MS
KIN3 YAR018C Nonessential serine/threonine protein kinase physical 1 1 1 Two-hybrid
END3 YNL084C EH domain-containing protein involved in endocytosis physical 1 1 1 Two-hybrid
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family genetic 1 1 1 Synthetic Growth Defect
HDA2 YDR295C Subunit of HDA1 histone deacetylase complex physical 1 1 1 Two-hybrid
MEC1 YBR136W Genome integrity checkpoint protein and PI kinase superfamily member physical 1 1 1 Affinity Capture-MS
CMR1 YDL156W Nuclear protein with role in transcription, protein quality control genetic 1 1 1 Negative Genetic
MUM2 YBR057C Protein essential for meiotic DNA replication and sporulation physical 1 1 1 Two-hybrid
MYO2 YOR326W Type V myosin motor involved in actin-based transport of cargos physical 1 1 1 Two-hybrid
HSP82 YPL240C Hsp90 chaperone genetic 1 1 1 Synthetic Growth Defect
PEP4 YPL154C Vacuolar aspartyl protease (proteinase A) genetic 1 1 1 Synthetic Rescue
PGD1 YGL025C Subunit of the RNA polymerase II mediator complex physical 1 1 1 Two-hybrid
SCS2 YER120W Integral ER membrane protein, regulates phospholipid metabolism genetic 1 1 1 Synthetic Growth Defect
SEC13 YLR208W Structural component of 3 complexes physical 1 1 1 Affinity Capture-MS
SEC23 YPR181C GTPase-activating protein, stimulates the GTPase activity of Sar1p physical 1 1 1 Affinity Capture-MS
RPT5 YOR117W ATPase of the 19S regulatory particle of the 26S proteasome physical 1 1 1 Two-hybrid
SEC65 YML105C Subunit of the signal recognition particle (SRP) genetic 1 1 1 Negative Genetic
IST2 YBR086C Cortical ER protein involved in ER-plasma membrane (PM) tethering genetic 1 1 1 Synthetic Growth Defect
ATG9 YDL149W Transmembrane protein involved in forming Cvt and autophagic vesicles physical 1 1 1 Affinity Capture-MS
BCK1 YJL095W MAPKKK acting in the protein kinase C signaling pathway genetic 1 1 1 Dosage Growth Defect
BRO1 YPL084W Cytoplasmic class E vacuolar protein sorting (VPS) factor genetic 1 1 1 Phenotypic Enhancement
VPS4 YPR173C AAA-ATPase involved in multivesicular body (MVB) protein sorting genetic 1 1 1 Phenotypic Suppression
SNF8 YPL002C Component of the ESCRT-II complex physical 1 1 1 Affinity Capture-Western
SNF8 YPL002C Component of the ESCRT-II complex genetic 1 1 1 Phenotypic Suppression
VPS24 YKL041W One of four subunits of the ESCRT-III complex genetic 1 1 1 Synthetic Rescue
YDR541C YDR541C Aldehyde reductase physical 1 1 1 Two-hybrid
TEL1 YBL088C Protein kinase primarily involved in telomere length regulation physical 1 1 1 Affinity Capture-MS
SPC72 YAL047C Gamma-tubulin small complex (gamma-TuSC) receptor physical 1 1 1 Two-hybrid
TSC11 YER093C Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p) physical 1 1 1 Two-hybrid
SPC105 YGL093W Subunit of a kinetochore-microtubule binding complex physical 1 1 1 Two-hybrid
YET3 YDL072C Protein of unknown function physical 1 1 1 Two-hybrid
VAB2 YEL005C Subunit of the BLOC-1 complex involved in endosomal maturation physical 1 1 1 Two-hybrid
YAF9 YNL107W Subunit of NuA4 histone H4 acetyltransferase and SWR1 complexes physical 1 1 1 Two-hybrid
TUP1 YCR084C General repressor of transcription in complex with Cyc8p physical 1 1 1 Two-hybrid
STB2 YMR053C Protein that interacts with Sin3p in a two-hybrid assay physical 1 1 1 Two-hybrid
SSO1 YPL232W Plasma membrane t-SNARE physical 1 1 1 Two-hybrid
VPS30 YPL120W Subunit of phosphatidylinositol (PtdIns) 3-kinase complexes I and II physical 1 1 1 Affinity Capture-MS
VPS15 YBR097W Serine/threonine protein kinase involved in vacuolar protein sorting physical 1 1 1 Affinity Capture-MS
VPS34 YLR240W Phosphatidylinositol (PI) 3-kinase that synthesizes PI-3-phosphate physical 1 1 1 Affinity Capture-MS
SRC1 YML034W Inner nuclear membrane protein physical 1 1 1 PCA
SRC1 YML034W Inner nuclear membrane protein genetic 1 1 1 Synthetic Growth Defect
VMA1 YDL185W Subunit A of the V1 peripheral membrane domain of V-ATPase genetic 1 1 1 Synthetic Growth Defect
TOR1 YJR066W PIK-related protein kinase and rapamycin target genetic 1 1 1 Synthetic Growth Defect
TIR1 YER011W Cell wall mannoprotein genetic 1 1 1 Phenotypic Enhancement
VMA4 YOR332W Subunit E of the V1 domain of the vacuolar H+-ATPase (V-ATPase) genetic 1 1 1 Phenotypic Enhancement
TAF1 YGR274C TFIID subunit, involved in RNA pol II transcription initiation genetic 1 1 1 Synthetic Lethality
VMA2 YBR127C Subunit B of V1 peripheral membrane domain of vacuolar H+-ATPase genetic 1 1 1 Synthetic Lethality
STH1 YIL126W ATPase component of the RSC chromatin remodeling complex genetic 1 1 1 Synthetic Growth Defect
SSP120 YLR250W Protein packaged into COPII vesicles for ER to Golgi trafficking genetic 1 1 1 Synthetic Growth Defect
YJU2 YKL095W Essential protein required for pre-mRNA splicing genetic 1 1 1 Negative Genetic
SUA7 YPR086W Transcription factor TFIIB genetic 1 1 1 Negative Genetic
VPS36 YLR417W Component of the ESCRT-II complex genetic 1 1 1 Phenotypic Suppression
VPS25 YJR102C Component of the ESCRT-II complex genetic 1 1 1 Phenotypic Suppression
STP22 YCL008C Component of the ESCRT-I complex genetic 1 1 1 Phenotypic Suppression
VPS38 YLR360W Part of a Vps34p phosphatidylinositol 3-kinase complex genetic 1 1 1 Phenotypic Suppression
SRN2 YLR119W Component of the ESCRT-I complex genetic 1 1 1 Phenotypic Suppression
TCB1 YOR086C Lipid-binding ER protein involved in ER-plasma membrane tethering genetic 1 1 1 Synthetic Growth Defect
TCB2 YNL087W ER protein involved in ER-plasma membrane tethering genetic 1 1 1 Synthetic Growth Defect
TCB3 YML072C Cortical ER protein involved in ER-plasma membrane tethering genetic 1 1 1 Synthetic Growth Defect
PUF3 YLL013C Protein of the mitochondrial outer surface physical 1 1 1 Affinity Capture-RNA
GAS1 YMR307W Beta-1,3-glucanosyltransferase required for cell wall assembly genetic 1 1 1 Dosage Rescue
ATG29 YPL166W Autophagy-specific protein physical 1 1 1 PCA
CNB1 YKL190W Calcineurin B genetic 1 1 1 Synthetic Rescue
ATG11 YPR049C Adapter protein for pexophagy and the Cvt targeting pathway physical 1 1 1 PCA
CYC8 YBR112C General transcriptional co-repressor genetic 1 1 1 Phenotypic Enhancement
SLT2 YHR030C Serine/threonine MAP kinase genetic 1 1 1 Dosage Growth Defect
CIK1 YMR198W Kinesin-associated protein physical 1 1 1 Two-hybrid
NOP53 YPL146C Nucleolar protein physical 1 1 1 Two-hybrid
MIG1 YGL035C Transcription factor involved in glucose repression genetic 1 1 1 Synthetic Growth Defect
DEF1 YKL054C RNAPII degradation factor physical 1 1 1 Affinity Capture-MS
BUB3 YOR026W Kinetochore checkpoint WD40 repeat protein genetic 1 1 1 Synthetic Lethality
MMS22 YLR320W Subunit of E3 ubiquitin ligase complex involved in replication repair physical 1 1 1 Affinity Capture-MS
BUD27 YFL023W Unconventional prefoldin protein involved in translation initiation physical 1 1 1 Two-hybrid
ATG13 YPR185W Regulatory subunit of the Atg1p signaling complex physical 1 1 1 Affinity Capture-MS
GZF3 YJL110C GATA zinc finger protein physical 1 1 1 Two-hybrid
NUF2 YOL069W Component of the kinetochore-associated Ndc80 complex physical 1 1 1 Two-hybrid
ATG27 YJL178C Type I membrane protein involved in autophagy and the Cvt pathway physical 1 1 1 Affinity Capture-MS
PEX13 YLR191W Peroxisomal importomer complex component physical 1 1 1 Two-hybrid
ATG23 YLR431C Peripheral membrane protein required for autophagy and CVT physical 1 1 1 Affinity Capture-MS
DBP5 YOR046C Cytoplasmic ATP-dependent RNA helicase of the DEAD-box family genetic 1 1 1 Synthetic Growth Defect
GEA1 YJR031C Guanine nucleotide exchange factor for ADP ribosylation factors (ARFs) physical 1 1 1 Two-hybrid
MAD1 YGL086W Coiled-coil protein involved in spindle-assembly checkpoint genetic 1 1 1 Synthetic Lethality
BIK1 YCL029C Microtubule-associated protein physical 1 1 1 Two-hybrid
SED5 YLR026C cis-Golgi t-SNARE syntaxin physical 1 1 1 Two-hybrid
ATG2 YNL242W Peripheral membrane protein required for autophagic vesicle formation physical 1 1 1 Affinity Capture-MS
SEC24 YIL109C Component of the Sec23p-Sec24p heterodimer of the COPII vesicle coat physical 1 1 1 Affinity Capture-MS
HMT1 YBR034C Nuclear SAM-dependent mono- and asymmetric methyltransferase genetic 1 1 1 Negative Genetic
MDV1 YJL112W Peripheral protein of cytosolic face of mitochondrial outer membrane physical 1 1 1 Two-hybrid
REC107 YJR021C Protein involved in early stages of meiotic recombination physical 1 1 1 Two-hybrid
CLA4 YNL298W Cdc42p-activated signal transducing kinase genetic 1 1 1 Synthetic Growth Defect
KEX2 YNL238W Kexin, a subtilisin-like protease (proprotein convertase) genetic 1 1 1 Dosage Rescue
AUR1 YKL004W Phosphatidylinositol:ceramide phosphoinositol transferase genetic 1 1 1 Negative Genetic
BSD2 YBR290W Heavy metal ion homeostasis protein genetic 1 1 1 Phenotypic Enhancement
DID2 YKR035W-A Class E protein of the vacuolar protein-sorting (Vps) pathway genetic 1 1 1 Synthetic Growth Defect
ENT1 YDL161W Epsin-like protein involved in endocytosis and actin patch assembly genetic 1 1 1 Synthetic Lethality
PDS5 YMR076C Cohesion maintenance factor physical 1 1 1 Two-hybrid
MDM1 YML104C PtdIns-3-P binding protein that tethers the ER to vacuoles at NVJs physical 1 1 1 Two-hybrid
COY1 YKL179C Golgi membrane protein with similarity to mammalian CASP physical 1 1 1 Two-hybrid
HSK3 YKL138C-A Essential subunit of the Dam1 complex (aka DASH complex) physical 1 1 1 Two-hybrid
BUL2 YML111W Alpha-arrestin, component of the Rsp5p E3-ubiquitin ligase complex physical 1 1 1 Two-hybrid
PMR1 YGL167C High affinity Ca2+/Mn2+ P-type ATPase genetic 1 1 1 Dosage Rescue
ANB1 YJR047C Translation elongation factor eIF-5A genetic 1 1 1 Phenotypic Enhancement
SAC1 YKL212W Phosphatidylinositol phosphate phosphatase genetic 1 1 1 Synthetic Lethality
GIS2 YNL255C Translational activator for mRNAs with internal ribosome entry sites physical 1 1 1 Affinity Capture-RNA
SCS22 YBL091C-A Protein involved in regulation of phospholipid metabolism genetic 1 1 1 Synthetic Growth Defect
SMF1 YOL122C Divalent metal ion transporter genetic 1 1 1 Phenotypic Suppression
RRT2 YBR246W Methylesterase performing penultimate step of diphthamide biosynthesis genetic 1 1 1 Phenotypic Enhancement
ENA1 YDR040C P-type ATPase sodium pump genetic 1 1 1 Dosage Rescue
ATG15 YCR068W Phospholipase genetic 1 1 1 Phenotypic Suppression
DSC3 YOR223W Subunit of the DSC ubiquitin ligase complex physical 1 1 1 Two-hybrid
LAM4 YHR080C Sterol-binding protein that localizes to puncta in the cortical ER physical 1 1 1 Two-hybrid
ARR1 YPR199C Transcriptional activator of the basic leucine zipper (bZIP) family physical 1 1 1 Two-hybrid
CDC1 YDR182W Putative mannose-ethanolamine phosphate phosphodiesterase genetic 1 1 1 Synthetic Rescue
HMS2 YJR147W Protein with similarity to heat shock transcription factors physical 1 1 1 Two-hybrid
APQ12 YIL040W Nuclear envelope/ER integral membrane protein genetic 1 1 1 Synthetic Growth Defect
DAN1 YJR150C Cell wall mannoprotein genetic 1 1 1 Phenotypic Enhancement