Standard name Systematic name Name description Description
HMT1 YBR034C Nuclear SAM-dependent mono- and asymmetric methyltransferase Nuclear SAM-dependent mono- and asymmetric methyltransferase; modifies hnRNPs, including Npl3p and Hrp1p, affecting their activity and nuclear export; methylates U1 snRNP protein Snp1p, ribosomal protein Rps2p, and histones H3 and H4; interacts genetically with genes encoding components of Rpd3(L) and this interaction is important for Rpd3 recruitment to the subtelomeric region
Visualize the interactome of HMT1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.927 0.935 0.908
Nucleus 0.062 NaN NaN
Vac/Vac Memb 0.266 0.088 0.163

GFP localization & abundance

GFP localization GFP abundance
cytoplasm, nucleus 37600

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
HMT1 9 0 0 0 0

Enzyme information

Catalyzed reactions in Yeast8
r_0541 (hnRNP arginine N-methyltransferase)

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
NPL3 YDR432W RNA-binding protein physical 15 6 13 Two-hybrid, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Affinity Capture-Western, Biochemical Activity, Affinity Capture-MS, Biochemical Activity, Biochemical Activity, PCA, Biochemical Activity, Reconstituted Complex, Biochemical Activity
HMT1 YBR034C Nuclear SAM-dependent mono- and asymmetric methyltransferase physical 8 6 5 Co-crystal Structure, Reconstituted Complex, Co-fractionation, Affinity Capture-MS, Affinity Capture-Western, PCA, Reconstituted Complex, Reconstituted Complex
HRP1 YOL123W Subunit of cleavage factor I physical 6 3 6 Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Affinity Capture-MS, PCA
NPL3 YDR432W RNA-binding protein genetic 5 2 5 Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Dosage Rescue, Dosage Rescue
DBP3 YGL078C RNA-Dependent ATPase, member of DExD/H-box family genetic 5 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
STO1 YMR125W Large subunit of the nuclear mRNA cap-binding protein complex genetic 4 2 4 Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Negative Genetic
CBC2 YPL178W Small subunit of the heterodimeric cap binding complex with Sto1p genetic 4 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes genetic 4 3 3 Synthetic Rescue, Phenotypic Suppression, Negative Genetic, Negative Genetic
HHF1 YBR009C Histone H4 physical 4 2 3 Biochemical Activity, Affinity Capture-Western, Biochemical Activity, Biochemical Activity
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 4 2 3 Biochemical Activity, Biochemical Activity, Biochemical Activity, PCA
MUD2 YKL074C Protein involved in early pre-mRNA splicing genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
TGS1 YPL157W Trimethyl guanosine synthase, conserved nucleolar methyl transferase genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
MTR10 YOR160W Nuclear import receptor genetic 4 1 2 Synthetic Rescue, Synthetic Rescue, Synthetic Rescue, Synthetic Rescue
DBF2 YGR092W Ser/Thr kinase involved in transcription and stress response physical 4 3 1 Affinity Capture-Western, PCA, PCA, Biochemical Activity
NOP1 YDL014W Histone glutamine methyltransferase, modifies H2A at Q105 in nucleolus physical 3 1 3 Biochemical Activity, Biochemical Activity, Biochemical Activity
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 3 2 2 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-RNA
HHF2 YNL030W Histone H4 physical 3 2 2 Biochemical Activity, Affinity Capture-Western, Biochemical Activity
YHC1 YLR298C Component of the U1 snRNP complex required for pre-mRNA splicing genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SNF2 YOR290C Catalytic subunit of the SWI/SNF chromatin remodeling complex physical 3 3 1 Affinity Capture-MS, Affinity Capture-Western, Biochemical Activity
SCD6 YPR129W Repressor of translation initiation physical 3 3 1 Two-hybrid, Affinity Capture-Western, Reconstituted Complex
PPH22 YDL188C Catalytic subunit of protein phosphatase 2A, PP2A physical 3 2 1 Affinity Capture-Western, PCA, PCA
ARC1 YGL105W Protein that binds tRNA and methionyl- and glutamyl-tRNA synthetases genetic 2 2 2 Negative Genetic, Dosage Growth Defect
HHT1 YBR010W Histone H3 physical 2 2 2 Affinity Capture-Western, Biochemical Activity
BFR1 YOR198C Component of mRNP complexes associated with polyribosomes physical 2 2 2 Affinity Capture-MS, Affinity Capture-RNA
CCZ1 YBR131W Subunit of a heterodimeric guanine nucleotide exchange factor (GEF) genetic 2 2 2 Positive Genetic, Dosage Growth Defect
SBP1 YHL034C Protein that binds eIF4G and has a role in repression of translation physical 2 2 2 Biochemical Activity, Affinity Capture-MS
SNP1 YIL061C Component of U1 snRNP required for mRNA splicing via spliceosome physical 2 2 2 Two-hybrid, Biochemical Activity
VMA21 YGR105W Integral membrane protein required for V-ATPase function genetic 2 2 2 Synthetic Growth Defect, Positive Genetic
RIM13 YMR154C Calpain-like cysteine protease genetic 2 2 2 Negative Genetic, Dosage Growth Defect
RSC2 YLR357W Component of the RSC chromatin remodeling complex genetic 2 2 2 Negative Genetic, Dosage Growth Defect
VPS17 YOR132W Subunit of the membrane-associated retromer complex genetic 2 2 2 Negative Genetic, Dosage Growth Defect
ERG3 YLR056W C-5 sterol desaturase genetic 2 2 2 Negative Genetic, Dosage Growth Defect
GWT1 YJL091C Protein involved in the inositol acylation of GlcN-PI genetic 2 1 2 Negative Genetic, Negative Genetic
GAR1 YHR089C Protein component of the H/ACA snoRNP pseudouridylase complex physical 2 1 2 Biochemical Activity, Biochemical Activity
CDC23 YHR166C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 2 1 2 Negative Genetic, Negative Genetic
DUO1 YGL061C Essential subunit of the Dam1 complex (aka DASH complex) genetic 2 1 2 Negative Genetic, Negative Genetic
APC5 YOR249C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 2 1 2 Negative Genetic, Negative Genetic
NSR1 YGR159C Nucleolin, nucleolar protein that binds nuclear localization sequences physical 2 1 2 Biochemical Activity, Biochemical Activity
MPT5 YGL178W mRNA-binding protein of the PUF family physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
PUF3 YLL013C Protein of the mitochondrial outer surface physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
KCH1 YJR054W Potassium transporter that mediates K+ influx genetic 2 1 2 Negative Genetic, Negative Genetic
RPL40B YKR094C Ubiquitin-ribosomal 60S subunit protein L40B fusion protein genetic 2 1 2 Negative Genetic, Negative Genetic
TEL2 YGR099W Subunit of the ASTRA complex, involved in chromatin remodeling genetic 2 1 2 Negative Genetic, Negative Genetic
CTI6 YPL181W Component of the Rpd3L histone deacetylase complex genetic 2 2 1 Negative Genetic, Synthetic Growth Defect
BRE5 YNR051C Ubiquitin protease cofactor physical 2 2 1 Affinity Capture-MS, Affinity Capture-Western
SSD1 YDR293C Translational repressor physical 2 2 1 Affinity Capture-MS, Affinity Capture-Western
MTR4 YJL050W RNA duplex-sensing translocase physical 2 2 1 Affinity Capture-MS, Affinity Capture-Western
SUM1 YDR310C Transcriptional repressor that regulates middle-sporulation genes physical 2 2 1 Affinity Capture-MS, Affinity Capture-Western
PHO23 YNL097C Component of the Rpd3L histone deacetylase complex genetic 2 2 1 Negative Genetic, Synthetic Growth Defect
RXT2 YBR095C Component of the histone deacetylase Rpd3L complex genetic 2 2 1 Negative Genetic, Synthetic Growth Defect
SAP30 YMR263W Component of Rpd3L histone deacetylase complex genetic 2 2 1 Negative Genetic, Synthetic Growth Defect
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes genetic 2 2 1 Synthetic Rescue, Phenotypic Enhancement
CDC36 YDL165W Component of the CCR4-NOT core complex, involved in mRNA decapping physical 2 1 1 Affinity Capture-Western, Affinity Capture-Western
POP2 YNR052C Subunit of Ccr4-Not complex that mediates 3' to 5' mRNA deadenylation physical 2 1 1 Affinity Capture-Western, Affinity Capture-Western
TIM13 YGR181W Mitochondrial intermembrane space protein genetic 2 1 1 Negative Genetic, Negative Genetic
MED6 YHR058C Subunit of the RNA polymerase II mediator complex genetic 2 1 1 Negative Genetic, Negative Genetic
SEN1 YLR430W ATP-dependent 5' to 3' RNA/DNA and DNA helicase genetic 2 1 1 Negative Genetic, Negative Genetic
SGV1 YPR161C Cyclin (Bur2p)-dependent protein kinase genetic 2 1 1 Negative Genetic, Negative Genetic
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
SPT20 YOL148C Subunit of the SAGA transcriptional regulatory complex regulation 1 1 1 DNA to cDNA expression microarray evidence
XBP1 YIL101C Transcriptional repressor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
REB1 YBR049C RNA polymerase I enhancer binding protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SRB5 YGR104C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RPC31 YNL151C RNA polymerase III subunit C31 regulation 1 1 1 in vitro methylation assay evidence
ESF1 YDR365C Nucleolar protein involved in pre-rRNA processing physical 1 1 1 Affinity Capture-MS
DBP9 YLR276C DEAD-box protein required for 27S rRNA processing physical 1 1 1 PCA
ARX1 YDR101C Nuclear export factor for the ribosomal pre-60S subunit physical 1 1 1 PCA
HCR1 YLR192C eIF3j component of translation initiation factor 3 (eIF3) physical 1 1 1 Affinity Capture-MS
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 1 1 1 Positive Genetic
ALA1 YOR335C Cytoplasmic and mitochondrial alanyl-tRNA synthetase physical 1 1 1 Affinity Capture-MS
CDC39 YCR093W Subunit of the CCR4-NOT1 core complex physical 1 1 1 Affinity Capture-MS
BMS1 YPL217C GTPase required for ribosomal subunit synthesis and rRNA processing genetic 1 1 1 Negative Genetic
APC1 YNL172W Largest subunit of the Anaphase-Promoting Complex/Cyclosome genetic 1 1 1 Negative Genetic
ARD1 YHR013C Subunit of protein N-terminal acetyltransferase NatA genetic 1 1 1 Negative Genetic
BEM1 YBR200W Protein containing SH3-domains genetic 1 1 1 Negative Genetic
ASC1 YMR116C G-protein beta subunit and guanine dissociation inhibitor for Gpa2p genetic 1 1 1 Dosage Growth Defect
BEM2 YER155C Rho GTPase activating protein (RhoGAP) genetic 1 1 1 Negative Genetic
CAF130 YGR134W Subunit of the CCR4-NOT transcriptional regulatory complex genetic 1 1 1 Positive Genetic
CDC24 YAL041W Guanine nucleotide exchange factor (GEF) for Cdc42p genetic 1 1 1 Negative Genetic
BNI1 YNL271C Formin physical 1 1 1 Affinity Capture-MS
BNI1 YNL271C Formin genetic 1 1 1 Negative Genetic
CTF18 YMR078C Subunit of a complex with Ctf8p genetic 1 1 1 Positive Genetic
ENO1 YGR254W Enolase I, a phosphopyruvate hydratase physical 1 1 1 Affinity Capture-MS
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator genetic 1 1 1 Dosage Growth Defect
HIS4 YCL030C Multifunctional enzyme containing phosphoribosyl-ATP pyrophosphatase genetic 1 1 1 Dosage Growth Defect
ADA2 YDR448W Transcription coactivator genetic 1 1 1 Negative Genetic
AFG2 YLR397C ATPase of the CDC48/PAS1/SEC18 (AAA) family, forms a hexameric complex physical 1 1 1 Affinity Capture-MS
GIM3 YNL153C Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Negative Genetic
GIM5 YML094W Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Negative Genetic
HMO1 YDR174W Chromatin associated high mobility group (HMG) family member physical 1 1 1 Affinity Capture-MS
DOA4 YDR069C Ubiquitin hydrolase genetic 1 1 1 Negative Genetic
DEP1 YAL013W Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
ADE3 YGR204W Cytoplasmic trifunctional enzyme genetic 1 1 1 Negative Genetic
BRR1 YPR057W snRNP protein component of spliceosomal snRNPs physical 1 1 1 Biochemical Activity
HFI1 YPL254W Adaptor protein required for structural integrity of the SAGA complex genetic 1 1 1 Negative Genetic
CCT6 YDR188W Subunit of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Negative Genetic
BRE2 YLR015W Subunit of COMPASS (Set1C) complex genetic 1 1 1 Dosage Growth Defect
DIA4 YHR011W Probable mitochondrial seryl-tRNA synthetase physical 1 1 1 Biochemical Activity
CDC13 YDL220C Single stranded DNA-binding protein found at TG1-3 telomere G-tails genetic 1 1 1 Negative Genetic
FPR3 YML074C Nucleolar peptidyl-prolyl cis-trans isomerase (PPIase) genetic 1 1 1 Positive Genetic
EGD2 YHR193C Alpha subunit of the nascent polypeptide-associated complex (NAC) genetic 1 1 1 Positive Genetic
AKL1 YBR059C Ser/Thr protein kinase physical 1 1 1 Affinity Capture-MS
GRR1 YJR090C F-box protein component of an SCF ubiquitin-ligase complex genetic 1 1 1 Negative Genetic
FDO1 YMR144W Protein involved in directionality of mating type switching physical 1 1 1 Affinity Capture-MS
APM3 YBR288C Mu3-like subunit of the clathrin associated protein complex (AP-3) genetic 1 1 1 Positive Genetic
GET2 YER083C Subunit of the GET complex genetic 1 1 1 Dosage Growth Defect
DUN1 YDL101C Cell-cycle checkpoint S/T protein kinase physical 1 1 1 PCA
ARG4 YHR018C Argininosuccinate lyase genetic 1 1 1 Dosage Growth Defect
DYN2 YDR424C Cytoplasmic light chain dynein, microtubule motor protein genetic 1 1 1 Positive Genetic
FUM1 YPL262W Fumarase genetic 1 1 1 Dosage Growth Defect
CDC20 YGL116W Activator of anaphase-promoting complex/cyclosome (APC/C) genetic 1 1 1 Negative Genetic
COS111 YBR203W Protein required for antifungal drug ciclopirox olamine resistance physical 1 1 1 Affinity Capture-MS
CDC60 YPL160W Cytosolic leucyl tRNA synthetase physical 1 1 1 Affinity Capture-MS
GRS1 YBR121C Cytoplasmic and mitochondrial glycyl-tRNA synthase genetic 1 1 1 Negative Genetic
GLE1 YDL207W Cytoplasmic nucleoporin required for polyadenylated mRNA export physical 1 1 1 PCA
CDC4 YFL009W F-box protein required for both the G1/S and G2/M phase transitions genetic 1 1 1 Negative Genetic
FRS2 YFL022C Alpha subunit of cytoplasmic phenylalanyl-tRNA synthetase physical 1 1 1 Affinity Capture-MS
CTF13 YMR094W Subunit of the CBF3 complex genetic 1 1 1 Negative Genetic
CHS1 YNL192W Chitin synthase I physical 1 1 1 Affinity Capture-MS
AIR1 YIL079C Zinc knuckle protein physical 1 1 1 Reconstituted Complex
CIA1 YDR267C Component of cytosolic iron-sulfur protein assembly (CIA) machinery genetic 1 1 1 Negative Genetic
BUB3 YOR026W Kinetochore checkpoint WD40 repeat protein genetic 1 1 1 Dosage Growth Defect
BIR1 YJR089W Subunit of chromosomal passenger complex (CPC) genetic 1 1 1 Negative Genetic
ADE2 YOR128C Phosphoribosylaminoimidazole carboxylase physical 1 1 1 PCA
EBS1 YDR206W Protein involved in translation inhibition and nonsense-mediated decay physical 1 1 1 Affinity Capture-MS
ARG81 YML099C Zinc finger transcription factor involved in arginine-responsive genes genetic 1 1 1 Positive Genetic
GTR1 YML121W Subunit of a TORC1-stimulating GTPase and the EGO/GSE complex genetic 1 1 1 Dosage Growth Defect
DON1 YDR273W Meiosis-specific component of the spindle pole body physical 1 1 1 PCA
CDC34 YDR054C Ubiquitin-conjugating enzyme (E2) physical 1 1 1 PCA
ERC1 YHR032W Member of the multi-drug and toxin extrusion (MATE) family physical 1 1 1 Affinity Capture-MS
FIS1 YIL065C Protein involved in mitochondrial fission and peroxisome abundance genetic 1 1 1 Positive Genetic
APC11 YDL008W Catalytic core subunit, Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Negative Genetic
CDC27 YBL084C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Negative Genetic
ELP3 YPL086C Subunit of Elongator complex genetic 1 1 1 Dosage Growth Defect
DOC1 YGL240W Processivity factor physical 1 1 1 Two-hybrid
CET1 YPL228W RNA 5'-triphosphatase involved in mRNA 5' capping genetic 1 1 1 Negative Genetic
ARP6 YLR085C Actin-related protein that binds nucleosomes physical 1 1 1 Affinity Capture-MS
DAL81 YIR023W Positive regulator of genes in multiple nitrogen degradation pathways genetic 1 1 1 Dosage Growth Defect
BDP1 YNL039W Essential subunit of RNA polymerase III transcription factor (TFIIIB) physical 1 1 1 Affinity Capture-Western
CSE4 YKL049C Centromeric histone H3-like protein genetic 1 1 1 Negative Genetic
DBP5 YOR046C Cytoplasmic ATP-dependent RNA helicase of the DEAD-box family genetic 1 1 1 Positive Genetic
ELO3 YLR372W Elongase genetic 1 1 1 Negative Genetic
EXO1 YOR033C 5'-3' exonuclease and flap-endonuclease genetic 1 1 1 Negative Genetic
GCD10 YNL062C Subunit of tRNA (1-methyladenosine) methyltransferase with Gcd14p physical 1 1 1 PCA
GLN3 YER040W Transcriptional activator in nitrogen catabolite repression system genetic 1 1 1 Negative Genetic
GAL10 YBR019C UDP-glucose-4-epimerase genetic 1 1 1 Synthetic Rescue
GYP1 YOR070C Cis-golgi GTPase-activating protein (GAP) for yeast Rabs genetic 1 1 1 Dosage Growth Defect
LSM8 YJR022W Lsm (Like Sm) protein physical 1 1 1 Two-hybrid
HRB1 YNL004W Poly(A+) RNA-binding protein physical 1 1 1 Biochemical Activity
NPP2 YEL016C Nucleotide pyrophosphatase/phosphodiesterase physical 1 1 1 Affinity Capture-MS
NKP2 YLR315W Central kinetochore protein and subunit of the Ctf19 complex physical 1 1 1 Affinity Capture-MS
SBP1 YHL034C Protein that binds eIF4G and has a role in repression of translation genetic 1 1 1 Positive Genetic
MRPS35 YGR165W Mitochondrial ribosomal protein of the small subunit physical 1 1 1 Two-hybrid
RPN1 YHR027C Non-ATPase base subunit of the 19S RP of the 26S proteasome physical 1 1 1 Affinity Capture-MS
RPN11 YFR004W Metalloprotease subunit of 19S regulatory particle physical 1 1 1 Affinity Capture-MS
POP2 YNR052C Subunit of Ccr4-Not complex that mediates 3' to 5' mRNA deadenylation genetic 1 1 1 Positive Genetic
TBF1 YPL128C Telobox-containing general regulatory factor physical 1 1 1 Affinity Capture-MS
PNG1 YPL096W Conserved peptide N-glycanase physical 1 1 1 Affinity Capture-MS
SRO9 YCL037C Cytoplasmic RNA-binding protein physical 1 1 1 Affinity Capture-MS
RRP1 YDR087C Essential evolutionarily conserved nucleolar protein physical 1 1 1 Affinity Capture-MS
SNF2 YOR290C Catalytic subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Negative Genetic
MLH1 YMR167W Protein required for mismatch repair in mitosis and meiosis physical 1 1 1 Affinity Capture-MS
RTN1 YDR233C Reticulon protein physical 1 1 1 Affinity Capture-MS
YJU3 YKL094W Monoglyceride lipase (MGL) that hydrolyzes fatty acid ethyl esters physical 1 1 1 Affinity Capture-MS
MRP10 YDL045W-A Mitochondrial ribosomal protein of the small subunit physical 1 1 1 Affinity Capture-MS
VPS13 YLL040C Lipid transport protein involved in prospore membrane morphogenesis physical 1 1 1 Affinity Capture-MS
RGC1 YPR115W Putative regulator of the Fps1p glycerol channel physical 1 1 1 Affinity Capture-MS
MDS3 YGL197W Putative component of the TOR regulatory pathway physical 1 1 1 Affinity Capture-MS
LIP5 YOR196C Protein involved in biosynthesis of the coenzyme lipoic acid physical 1 1 1 Affinity Capture-MS
NRP1 YDL167C Putative RNA binding protein of unknown function physical 1 1 1 Affinity Capture-MS
PGI1 YBR196C Glycolytic enzyme phosphoglucose isomerase physical 1 1 1 Affinity Capture-MS
MDY2 YOL111C Protein involved in inserting tail-anchored proteins into ER membranes physical 1 1 1 Affinity Capture-MS
IRA1 YBR140C GTPase-activating protein physical 1 1 1 Affinity Capture-MS
PMA2 YPL036W Plasma membrane H+-ATPase physical 1 1 1 Affinity Capture-MS
UBP13 YBL067C Ubiquitin-specific protease that cleaves Ub-protein fusions physical 1 1 1 Affinity Capture-MS
PRB1 YEL060C Vacuolar proteinase B (yscB) with H3 N-terminal endopeptidase activity physical 1 1 1 Affinity Capture-MS
PRB1 YEL060C Vacuolar proteinase B (yscB) with H3 N-terminal endopeptidase activity genetic 1 1 1 Dosage Growth Defect
NUP100 YKL068W FG-nucleoporin component of central core of the nuclear pore complex physical 1 1 1 Affinity Capture-MS
MDH1 YKL085W Mitochondrial malate dehydrogenase physical 1 1 1 Affinity Capture-MS
HTB1 YDR224C Histone H2B physical 1 1 1 Affinity Capture-MS
PEP1 YBL017C Type I transmembrane sorting receptor for multiple vacuolar hydrolases physical 1 1 1 Affinity Capture-MS
RBH2 YJR030C Putative protein of unknown function physical 1 1 1 Affinity Capture-MS
SET3 YKR029C Defining member of the SET3 histone deacetylase complex physical 1 1 1 Affinity Capture-MS
TOM70 YNL121C Component of the TOM (translocase of outer membrane) complex physical 1 1 1 Affinity Capture-MS
VIP1 YLR410W Bifunctional inositol pyrophosphate kinase and phosphatase physical 1 1 1 Affinity Capture-MS
RAS2 YNL098C GTP-binding protein physical 1 1 1 Affinity Capture-MS
SET1 YHR119W Histone methyltransferase, subunit of the COMPASS (Set1C) complex physical 1 1 1 Affinity Capture-MS
SND1 YDR186C Protein involved in SRP-independent targeting of substrates to the ER physical 1 1 1 Affinity Capture-MS
SIR2 YDL042C Conserved NAD+ dependent histone deacetylase of the Sirtuin family physical 1 1 1 Affinity Capture-MS
HOF1 YMR032W F-BAR protein that regulates actin cytoskeleton organization physical 1 1 1 Affinity Capture-MS
SAC6 YDR129C Fimbrin, actin-bundling protein physical 1 1 1 Affinity Capture-MS
UBX4 YMR067C UBX domain-containing protein that interacts with Cdc48p physical 1 1 1 Affinity Capture-MS
YLR225C YLR225C Putative protein of unknown function physical 1 1 1 Affinity Capture-MS
PYP1 YNL010W Sugar alcohol phosphatase physical 1 1 1 Affinity Capture-MS
SPR28 YDR218C Sporulation-specific homolog of the CDC3/10/11/12 family of genes physical 1 1 1 Affinity Capture-MS
IRA2 YOL081W GTPase-activating protein physical 1 1 1 Affinity Capture-MS
YHR214C-C YHR214C-C Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Affinity Capture-MS
XRS2 YDR369C FHA domain-containing component of the Mre11 complex physical 1 1 1 Affinity Capture-MS
PCA1 YBR295W Cadmium transporting P-type ATPase physical 1 1 1 Affinity Capture-MS
PIP2 YOR363C Autoregulatory, oleate-activated transcription factor physical 1 1 1 Affinity Capture-MS
SIP1 YDR422C One of three alternate beta-subunits of the Snf1p kinase complex physical 1 1 1 Affinity Capture-MS
PRP2 YNR011C RNA-dependent DExD/H-box ATPase physical 1 1 1 Affinity Capture-MS
LAP2 YNL045W Leucyl aminopeptidase yscIV with epoxide hydrolase activity physical 1 1 1 Affinity Capture-MS
SEC7 YDR170C Guanine nucleotide exchange factor (GEF) for ADP ribosylation factors physical 1 1 1 Affinity Capture-MS
IQG1 YPL242C Actin filament binding protein that enhances actin ring formation physical 1 1 1 Affinity Capture-MS
RTG1 YOL067C Transcription factor (bHLH) involved in interorganelle communication physical 1 1 1 Affinity Capture-MS
RPO21 YDL140C RNA polymerase II largest subunit B220 physical 1 1 1 Affinity Capture-MS
TIF4632 YGL049C Translation initiation factor eIF4G and scaffold protein physical 1 1 1 Affinity Capture-MS
RAD52 YML032C Protein involved in homologous recombination physical 1 1 1 Affinity Capture-MS
SWI6 YLR182W Transcription cofactor physical 1 1 1 Affinity Capture-MS
MSH4 YFL003C Protein involved in meiotic recombination physical 1 1 1 Affinity Capture-MS
YHR131C YHR131C Putative protein of unknown function physical 1 1 1 Affinity Capture-MS
RPC82 YPR190C RNA polymerase III subunit C82 physical 1 1 1 Affinity Capture-MS
SHP1 YBL058W UBX domain-containing substrate adaptor for Cdc48p physical 1 1 1 Affinity Capture-MS
MVP1 YMR004W Protein required for sorting proteins to the vacuole physical 1 1 1 Affinity Capture-MS
PPA2 YMR267W Mitochondrial inorganic pyrophosphatase physical 1 1 1 Affinity Capture-MS
VPS74 YDR372C Golgi PI4K effector, PtdIns4P sensor, and retention receptor physical 1 1 1 Affinity Capture-MS
HTB2 YBL002W Histone H2B physical 1 1 1 Affinity Capture-MS
ORC1 YML065W Largest subunit of the origin recognition complex physical 1 1 1 Affinity Capture-MS
NVJ2 YPR091C Lipid-binding ER protein, enriched at nucleus-vacuolar junctions (NVJ) physical 1 1 1 Affinity Capture-MS
HXT7 YDR342C High-affinity glucose transporter physical 1 1 1 Affinity Capture-MS
ISN1 YOR155C Inosine 5'-monophosphate (IMP)-specific 5'-nucleotidase physical 1 1 1 Affinity Capture-MS
PSD2 YGR170W Phosphatidylserine decarboxylase of the Golgi and vacuolar membranes physical 1 1 1 Affinity Capture-MS
ROM2 YLR371W Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p physical 1 1 1 Affinity Capture-MS
TOF1 YNL273W Subunit of a replication-pausing checkpoint complex physical 1 1 1 Affinity Capture-MS
UBP15 YMR304W Ubiquitin-specific protease involved in protein deubiquitination physical 1 1 1 Affinity Capture-MS
UTP14 YML093W Subunit of U3-containing Small Subunit (SSU) processome complex physical 1 1 1 Affinity Capture-MS
YML020W YML020W Putative protein of unknown function physical 1 1 1 Affinity Capture-MS
SNG1 YGR197C Protein involved in resistance to nitrosoguanidine and 6-azauracil physical 1 1 1 Affinity Capture-MS
SNG1 YGR197C Protein involved in resistance to nitrosoguanidine and 6-azauracil genetic 1 1 1 Negative Genetic
RTT102 YGR275W Component of both the SWI/SNF and RSC chromatin remodeling complexes physical 1 1 1 Affinity Capture-MS
MCO10 YOR020W-A Mitochondrial protein of unknown function physical 1 1 1 Affinity Capture-MS
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
RPS2 YGL123W Protein component of the small (40S) subunit physical 1 1 1 Biochemical Activity
RNH70 YGR276C 3'-5' exoribonuclease physical 1 1 1 PCA
RPL4A YBR031W Ribosomal 60S subunit protein L4A physical 1 1 1 PCA
RPL14B YHL001W Ribosomal 60S subunit protein L14B physical 1 1 1 PCA
LEU1 YGL009C Isopropylmalate isomerase physical 1 1 1 PCA
RNA14 YMR061W Component of the cleavage and polyadenylation factor I (CF I) physical 1 1 1 PCA
RNA14 YMR061W Component of the cleavage and polyadenylation factor I (CF I) genetic 1 1 1 Positive Genetic
NEM1 YHR004C Probable catalytic subunit of Nem1p-Spo7p phosphatase holoenzyme physical 1 1 1 PCA
PKH3 YDR466W Protein kinase with similarity to mammalian PDK1 and yeast Pkh1p/Phk2p physical 1 1 1 PCA
PKH2 YOL100W Serine/threonine protein kinase physical 1 1 1 PCA
TRA1 YHR099W Subunit of SAGA and NuA4 histone acetyltransferase complexes physical 1 1 1 PCA
TRA1 YHR099W Subunit of SAGA and NuA4 histone acetyltransferase complexes genetic 1 1 1 Synthetic Growth Defect
UBA2 YDR390C Subunit of heterodimeric nuclear SUMO activating enzyme E1 with Aos1p physical 1 1 1 PCA
PIB2 YGL023C Phosphatidylinositol 3-phosphate binding protein physical 1 1 1 PCA
LAM1 YHR155W Putative sterol transfer protein physical 1 1 1 PCA
RRP45 YDR280W Exosome non-catalytic core component physical 1 1 1 PCA
RPA12 YJR063W RNA polymerase I subunit A12.2 physical 1 1 1 PCA
RAD5 YLR032W DNA helicase/Ubiquitin ligase physical 1 1 1 PCA
TRP3 YKL211C Indole-3-glycerol-phosphate synthase physical 1 1 1 PCA
YFL040W YFL040W Putative transporter physical 1 1 1 PCA
STB2 YMR053C Protein that interacts with Sin3p in a two-hybrid assay physical 1 1 1 PCA
VTS1 YOR359W Flap-structured DNA-binding and RNA-binding protein physical 1 1 1 PCA
SEC26 YDR238C Essential beta-coat protein of the COPI coatomer physical 1 1 1 PCA
SCD6 YPR129W Repressor of translation initiation genetic 1 1 1 Synthetic Growth Defect
PUF2 YPR042C PUF family mRNA-binding protein physical 1 1 1 Affinity Capture-RNA
HTS1 YPR033C Cytoplasmic and mitochondrial histidine tRNA synthetase physical 1 1 1 Biochemical Activity
MPP10 YJR002W Component of the SSU processome and 90S preribosome physical 1 1 1 Biochemical Activity
MRD1 YPR112C Essential conserved small ribosomal subunit (40s) synthesis factor physical 1 1 1 Biochemical Activity
NUG1 YER006W GTPase that associates with nuclear 60S pre-ribosomes physical 1 1 1 Biochemical Activity
PRP43 YGL120C RNA helicase in the DEAH-box family physical 1 1 1 Biochemical Activity
RPA43 YOR340C RNA polymerase I subunit A43 physical 1 1 1 Biochemical Activity
RRP43 YCR035C Exosome non-catalytic core component physical 1 1 1 Biochemical Activity
SPP381 YBR152W mRNA splicing factor, component of U4/U6.U5 tri-snRNP physical 1 1 1 Biochemical Activity
UTP4 YDR324C Subunit of U3-containing 90S preribosome and SSU processome complexes physical 1 1 1 Biochemical Activity
PUF4 YGL014W Member of the PUF protein family physical 1 1 1 Affinity Capture-RNA
PHO4 YFR034C Basic helix-loop-helix (bHLH) transcription factor of the myc-family physical 1 1 1 Biochemical Activity
SNU56 YDR240C Component of U1 snRNP required for mRNA splicing via spliceosome genetic 1 1 1 Synthetic Lethality
UBI4 YLL039C Ubiquitin genetic 1 1 1 Negative Genetic
TRM7 YBR061C 2'-O-ribose methyltransferase genetic 1 1 1 Negative Genetic
NUP57 YGR119C FG-nucleoporin component of central core of the nuclear pore complex genetic 1 1 1 Negative Genetic
MRM1 YOR201C Ribose methyltransferase genetic 1 1 1 Negative Genetic
MSK1 YNL073W Mitochondrial lysine-tRNA synthetase genetic 1 1 1 Negative Genetic
TRM3 YDL112W 2'-O-ribose methyltransferase genetic 1 1 1 Positive Genetic
LOT5 YKL183W Protein of unknown function genetic 1 1 1 Positive Genetic
RNH201 YNL072W Ribonuclease H2 catalytic subunit genetic 1 1 1 Positive Genetic
TEF2 YBR118W Translational elongation factor EF-1 alpha genetic 1 1 1 Positive Genetic
SUI2 YJR007W Alpha subunit of the translation initiation factor eIF2 genetic 1 1 1 Positive Genetic
THP3 YPR045C Protein that may have a role in transcription elongation genetic 1 1 1 Positive Genetic
SRP101 YDR292C Signal recognition particle (SRP) receptor alpha subunit genetic 1 1 1 Negative Genetic
VOA1 YGR106C ER protein that functions in assembly of the V0 sector of V-ATPase genetic 1 1 1 Synthetic Growth Defect
VMA3 YEL027W Proteolipid subunit c of the V0 domain of vacuolar H(+)-ATPase genetic 1 1 1 Negative Genetic
HST3 YOR025W Sirtuin, histone H3 deacetylase genetic 1 1 1 Positive Genetic
ICP55 YER078C Mitochondrial aminopeptidase genetic 1 1 1 Positive Genetic
JEM1 YJL073W DnaJ-like chaperone required for nuclear membrane fusion during mating genetic 1 1 1 Positive Genetic
KRE28 YDR532C Subunit of a kinetochore-microtubule binding complex genetic 1 1 1 Negative Genetic
LDB16 YCL005W Protein involved in lipid droplet (LD) assembly genetic 1 1 1 Negative Genetic
LDB7 YBL006C Component of the RSC chromatin remodeling complex genetic 1 1 1 Negative Genetic
LYS1 YIR034C Saccharopine dehydrogenase (NAD+, L-lysine-forming) genetic 1 1 1 Negative Genetic
MAL12 YGR292W Maltase (alpha-D-glucosidase) genetic 1 1 1 Positive Genetic
MEF2 YJL102W Mitochondrial elongation factor involved in translational elongation genetic 1 1 1 Positive Genetic
MGM1 YOR211C Mitochondrial GTPase, present in complex with Ugo1p and Fzo1p genetic 1 1 1 Negative Genetic
MIP6 YHR015W Putative RNA-binding protein genetic 1 1 1 Negative Genetic
MRPL10 YNL284C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
MRPL13 YKR006C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
MRPL35 YDR322W Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
MRPL51 YPR100W Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
MSN1 YOL116W Transcriptional activator genetic 1 1 1 Positive Genetic
MSN5 YDR335W Karyopherin genetic 1 1 1 Negative Genetic
NGG1 YDR176W Subunit of chromatin modifying histone acetyltransferase complexes genetic 1 1 1 Negative Genetic
NGL3 YML118W 3'-5' exonuclease specific for poly-A RNAs genetic 1 1 1 Positive Genetic
NOT5 YPR072W Component of the CCR4-NOT core complex, involved in mRNA decapping genetic 1 1 1 Positive Genetic
NUT1 YGL151W Component of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
OCH1 YGL038C Mannosyltransferase of the cis-Golgi apparatus genetic 1 1 1 Negative Genetic
PEP12 YOR036W Target membrane receptor (t-SNARE) genetic 1 1 1 Negative Genetic
PEX14 YGL153W Central component of the peroxisomal importomer complex genetic 1 1 1 Negative Genetic
PFD1 YJL179W Subunit of heterohexameric prefoldin genetic 1 1 1 Negative Genetic
PHO80 YOL001W Cyclin genetic 1 1 1 Negative Genetic
PML39 YML107C Protein required for nuclear retention of unspliced pre-mRNAs genetic 1 1 1 Positive Genetic
POC4 YPL144W Component of a heterodimeric Poc4p-Irc25p chaperone genetic 1 1 1 Negative Genetic
POS5 YPL188W Mitochondrial NADH kinase genetic 1 1 1 Negative Genetic
PRE9 YGR135W Alpha 3 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
RAD51 YER095W Strand exchange protein genetic 1 1 1 Positive Genetic
RAD6 YGL058W Ubiquitin-conjugating enzyme (E2) genetic 1 1 1 Negative Genetic
RIB1 YBL033C GTP cyclohydrolase II genetic 1 1 1 Negative Genetic
RIM101 YHL027W Cys2His2 zinc-finger transcriptional repressor genetic 1 1 1 Negative Genetic
RIM20 YOR275C Protein involved in proteolytic activation of Rim101p genetic 1 1 1 Negative Genetic
RIM8 YGL045W Protein involved in proteolytic activation of Rim101p genetic 1 1 1 Negative Genetic
RMD6 YEL072W Protein required for sporulation genetic 1 1 1 Negative Genetic
RPL19A YBR084C-A Ribosomal 60S subunit protein L19A genetic 1 1 1 Positive Genetic
RPL31A YDL075W Ribosomal 60S subunit protein L31A genetic 1 1 1 Negative Genetic
RPL9A YGL147C Ribosomal 60S subunit protein L9A genetic 1 1 1 Negative Genetic
RXT3 YDL076C Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Positive Genetic
SEC28 YIL076W Epsilon-COP subunit of the coatomer genetic 1 1 1 Positive Genetic
SGF73 YGL066W Subunit of DUBm module of SAGA and SLIK genetic 1 1 1 Negative Genetic
SIN3 YOL004W Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 1 1 1 Negative Genetic
SIT4 YDL047W Ceramide-activated, type 2A-related serine-threonine phosphatase genetic 1 1 1 Negative Genetic
SLM5 YCR024C Mitochondrial asparaginyl-tRNA synthetase genetic 1 1 1 Negative Genetic
SNF6 YHL025W Subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Negative Genetic
SNF7 YLR025W One of four subunits of the ESCRT-III complex genetic 1 1 1 Negative Genetic
SNZ1 YMR096W Subunit of a two-component pyridoxal-5'-phosphate synthase genetic 1 1 1 Positive Genetic
SOH1 YGL127C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Positive Genetic
SPO13 YHR014W Meiotic regulator genetic 1 1 1 Negative Genetic
SPT2 YER161C Protein involved in negative regulation of transcription genetic 1 1 1 Negative Genetic
SSN8 YNL025C Cyclin-like component of RNA polymerase II holoenzyme genetic 1 1 1 Positive Genetic
STE50 YCL032W Adaptor protein for various signaling pathways genetic 1 1 1 Negative Genetic
SWC5 YBR231C Component of the SWR1 complex genetic 1 1 1 Negative Genetic
SWI3 YJL176C Subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Negative Genetic
TFB5 YDR079C-A Component of RNA polymerase II general transcription factor TFIIH genetic 1 1 1 Negative Genetic
VMA1 YDL185W Subunit A of the V1 peripheral membrane domain of V-ATPase genetic 1 1 1 Negative Genetic
THR1 YHR025W Homoserine kinase genetic 1 1 1 Negative Genetic
TPD3 YAL016W Regulatory subunit A of the heterotrimeric PP2A complex genetic 1 1 1 Negative Genetic
TRP1 YDR007W Phosphoribosylanthranilate isomerase genetic 1 1 1 Positive Genetic
TVP18 YMR071C Integral membrane protein genetic 1 1 1 Positive Genetic
UBP14 YBR058C Ubiquitin-specific protease genetic 1 1 1 Positive Genetic
UMP1 YBR173C Chaperone required for correct maturation of the 20S proteasome genetic 1 1 1 Negative Genetic
VMA5 YKL080W Subunit C of the V1 peripheral membrane domain of V-ATPase genetic 1 1 1 Negative Genetic
VMA7 YGR020C Subunit F of the V1 peripheral membrane domain of V-ATPase genetic 1 1 1 Negative Genetic
VMA8 YEL051W Subunit D of the V1 peripheral membrane domain of V-ATPase genetic 1 1 1 Negative Genetic
VPH2 YKL119C Integral membrane protein required for V-ATPase function genetic 1 1 1 Negative Genetic
VPS16 YPL045W Subunit of the HOPS and the CORVET complexes genetic 1 1 1 Negative Genetic
VPS20 YMR077C Myristoylated subunit of the ESCRT-III complex genetic 1 1 1 Negative Genetic
WHI5 YOR083W Repressor of G1 transcription genetic 1 1 1 Positive Genetic
YAR1 YPL239W Nucleocytoplasmic shuttling assembly chaperone genetic 1 1 1 Positive Genetic
YGK3 YOL128C Protein kinase related to mammalian GSK-3 glycogen synthase kinases genetic 1 1 1 Positive Genetic
YGL159W YGL159W Putative protein of unknown function genetic 1 1 1 Negative Genetic
YHI9 YHR029C Protein of unknown function genetic 1 1 1 Negative Genetic
YIP5 YGL161C Protein that interacts with Rab GTPases genetic 1 1 1 Negative Genetic
YJR011C YJR011C Putative protein of unknown function genetic 1 1 1 Negative Genetic
YKE2 YLR200W Subunit of the heterohexameric Gim/prefoldin protein complex genetic 1 1 1 Negative Genetic
YPR063C YPR063C ER-localized protein of unknown function genetic 1 1 1 Positive Genetic
YPR071W YPR071W Putative membrane protein genetic 1 1 1 Positive Genetic
YPR084W YPR084W Putative protein of unknown function genetic 1 1 1 Positive Genetic
YRB30 YGL164C RanGTP-binding protein genetic 1 1 1 Negative Genetic
SDS3 YIL084C Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Synthetic Growth Defect
UME1 YPL139C Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 1 1 1 Synthetic Growth Defect
UME6 YDR207C Rpd3L histone deacetylase complex subunit genetic 1 1 1 Synthetic Rescue
YKU70 YMR284W Subunit of the telomeric Ku complex (Yku70p-Yku80p) genetic 1 1 1 Negative Genetic
TTI1 YKL033W Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Positive Genetic
POP1 YNL221C Subunit of RNase MRP, nuclear RNase P and telomerase complexes genetic 1 1 1 Positive Genetic
SMX3 YPR182W Core Sm protein Sm F genetic 1 1 1 Positive Genetic
STP22 YCL008C Component of the ESCRT-I complex genetic 1 1 1 Positive Genetic
SOM1 YEL059C-A Subunit of the mitochondrial inner membrane peptidase (IMP) genetic 1 1 1 Positive Genetic
UBC1 YDR177W Ubiquitin-conjugating enzyme genetic 1 1 1 Negative Genetic
HYP2 YEL034W Translation elongation factor eIF-5A genetic 1 1 1 Negative Genetic
UTP8 YGR128C Nucleolar protein required for export of tRNAs from the nucleus genetic 1 1 1 Negative Genetic
KOG1 YHR186C Subunit of TORC1 genetic 1 1 1 Negative Genetic
TAO3 YIL129C Component of the RAM signaling network genetic 1 1 1 Negative Genetic
SSC1 YJR045C Hsp70 family ATPase genetic 1 1 1 Negative Genetic
MSL5 YLR116W Component of commitment complex genetic 1 1 1 Negative Genetic
PRP39 YML046W U1 snRNP protein involved in splicing genetic 1 1 1 Negative Genetic
TAF13 YML098W TFIID subunit (19 kDa) genetic 1 1 1 Negative Genetic
RRP5 YMR229C RNA binding protein involved in synthesis of 18S and 5.8S rRNAs genetic 1 1 1 Negative Genetic
RNA1 YMR235C GTPase activating protein (GAP) for Gsp1p genetic 1 1 1 Negative Genetic
RAP1 YNL216W Essential DNA-binding transcription regulator that binds many loci genetic 1 1 1 Negative Genetic
KRI1 YNL308C Essential nucleolar protein required for 40S ribosome biogenesis genetic 1 1 1 Negative Genetic
SEC12 YNR026C Guanine nucleotide exchange factor (GEF) genetic 1 1 1 Negative Genetic
RPB11 YOL005C RNA polymerase II subunit B12.5 genetic 1 1 1 Negative Genetic
RAT1 YOR048C Nuclear 5' to 3' single-stranded RNA exonuclease genetic 1 1 1 Negative Genetic
SWI1 YPL016W Subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Negative Genetic
RPN7 YPR108W Essential non-ATPase regulatory subunit of the 26S proteasome genetic 1 1 1 Negative Genetic
SNU23 YDL098C Component of the U4/U6.U5 snRNP complex genetic 1 1 1 Negative Genetic
TAF6 YGL112C Subunit (60 kDa) of TFIID and SAGA complexes genetic 1 1 1 Negative Genetic
MET30 YIL046W F-box protein containing five copies of the WD40 motif genetic 1 1 1 Negative Genetic
KRE9 YJL174W Glycoprotein involved in cell wall beta-glucan assembly genetic 1 1 1 Negative Genetic
PRE2 YPR103W Beta 5 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
LEA1 YPL213W Component of U2 snRNP complex genetic 1 1 1 Negative Genetic
RSM26 YJR101W Mitochondrial ribosomal protein of the small subunit genetic 1 1 1 Negative Genetic
RPS6B YBR181C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Dosage Growth Defect
THR4 YCR053W Threonine synthase genetic 1 1 1 Dosage Growth Defect
STE7 YDL159W Signal transducing MAP kinase kinase genetic 1 1 1 Dosage Growth Defect
LYS4 YDR234W Homoaconitase genetic 1 1 1 Dosage Growth Defect
IES1 YFL013C Subunit of the INO80 chromatin remodeling complex genetic 1 1 1 Dosage Growth Defect
ZRT1 YGL255W High-affinity zinc transporter of the plasma membrane genetic 1 1 1 Dosage Growth Defect
YGR122W YGR122W Protein that may be involved in pH regulation genetic 1 1 1 Dosage Growth Defect
SLT2 YHR030C Serine/threonine MAP kinase genetic 1 1 1 Dosage Growth Defect
ICE2 YIL090W Integral ER membrane protein with type-III transmembrane domains genetic 1 1 1 Dosage Growth Defect
JJJ1 YNL227C Co-chaperone that stimulates the ATPase activity of Ssa1p genetic 1 1 1 Dosage Growth Defect
VPS5 YOR069W Nexin-1 homolog genetic 1 1 1 Dosage Growth Defect
MED1 YPR070W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Dosage Growth Defect
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p genetic 1 1 1 Dosage Growth Defect
VPS53 YJL029C Component of the GARP (Golgi-associated retrograde protein) complex genetic 1 1 1 Dosage Growth Defect
YPT7 YML001W Rab family GTPase genetic 1 1 1 Dosage Growth Defect
URA5 YML106W Major orotate phosphoribosyltransferase (OPRTase) isozyme genetic 1 1 1 Dosage Growth Defect
MAC1 YMR021C Copper-sensing transcription factor genetic 1 1 1 Dosage Growth Defect
VAM10 YOR068C Protein involved in vacuole morphogenesis genetic 1 1 1 Dosage Growth Defect
RAM1 YDL090C Beta subunit of the CAAX farnesyltransferase (FTase) genetic 1 1 1 Dosage Growth Defect
TMA7 YLR262C-A Protein of unknown function that associates with ribosomes genetic 1 1 1 Dosage Growth Defect
MIR1 YJR077C Mitochondrial phosphate carrier genetic 1 1 1 Dosage Growth Defect
SIR3 YLR442C Silencing protein genetic 1 1 1 Dosage Growth Defect
VPS9 YML097C Guanine nucleotide exchange factor (GEF) and ubiquitin receptor genetic 1 1 1 Dosage Growth Defect
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 1 1 1 Positive Genetic
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 1 1 1 Positive Genetic
CLA4 YNL298W Cdc42p-activated signal transducing kinase genetic 1 1 1 Dosage Growth Defect
HHT2 YNL031C Histone H3 physical 1 1 1 Biochemical Activity
BCS1 YDR375C Protein translocase and chaperone required for Complex III assembly genetic 1 1 1 Dosage Growth Defect
HBT1 YDL223C Shmoo tip protein, substrate of Hub1p ubiquitin-like protein physical 1 1 1 Affinity Capture-MS
ERG28 YER044C Endoplasmic reticulum membrane protein genetic 1 1 1 Negative Genetic
FMP27 YLR454W Protein with structural similarity to lipid transport protein Vps13p physical 1 1 1 Affinity Capture-MS
HMG1 YML075C HMG-CoA reductase genetic 1 1 1 Positive Genetic
ADE1 YAR015W N-succinyl-5-aminoimidazole-4-carboxamide ribotide synthetase physical 1 1 1 Affinity Capture-MS
CSF1 YLR087C Protein with structural similarity to lipid transport protein Vps13p physical 1 1 1 Affinity Capture-MS
HEM14 YER014W Protoporphyrinogen oxidase physical 1 1 1 Affinity Capture-MS
ARI1 YGL157W NADPH-dependent aldehyde reductase genetic 1 1 1 Negative Genetic
BUL2 YML111W Alpha-arrestin, component of the Rsp5p E3-ubiquitin ligase complex physical 1 1 1 Affinity Capture-MS
ARG56 YER069W Acetylglutamate kinase and N-acetyl-gamma-glutamyl-phosphate reductase genetic 1 1 1 Negative Genetic
HIS6 YIL020C Enzyme that catalyzes the fourth step in the histidine pathway genetic 1 1 1 Dosage Growth Defect
CAJ1 YER048C Nuclear type II J heat shock protein of the E. coli dnaJ family physical 1 1 1 Affinity Capture-MS
GSH1 YJL101C Gamma glutamylcysteine synthetase genetic 1 1 1 Dosage Growth Defect
DOS2 YDR068W Protein of unknown function physical 1 1 1 Affinity Capture-MS
ARO2 YGL148W Bifunctional chorismate synthase and flavin reductase genetic 1 1 1 Negative Genetic
EST2 YLR318W Reverse transcriptase subunit of the telomerase holoenzyme genetic 1 1 1 Dosage Growth Defect
COX11 YPL132W Protein required for delivery of copper to Cox1p genetic 1 1 1 Positive Genetic
CHS2 YBR038W Chitin synthase II physical 1 1 1 Affinity Capture-MS
ERP4 YOR016C Member of the p24 family involved in ER to Golgi transport genetic 1 1 1 Positive Genetic
COS7 YDL248W Endosomal protein involved in turnover of plasma membrane proteins genetic 1 1 1 Negative Genetic
ADK2 YER170W Mitochondrial adenylate kinase genetic 1 1 1 Negative Genetic
BRR6 YGL247W Essential nuclear envelope integral membrane protein genetic 1 1 1 Negative Genetic
EDS1 YBR033W Putative zinc cluster protein, predicted to be a transcription factor genetic 1 1 1 Negative Genetic
EFM5 YGR001C S-adenosylmethionine-dependent lysine methyltransferase genetic 1 1 1 Negative Genetic
EMC10 YDR056C Putative protein of unknown function genetic 1 1 1 Negative Genetic
BIO4 YNR057C Dethiobiotin synthetase physical 1 1 1 PCA
HMI1 YOL095C Mitochondrial inner membrane localized ATP-dependent DNA helicase physical 1 1 1 Affinity Capture-MS
GPI11 YDR302W ER membrane protein involved in a late step of GPI anchor assembly genetic 1 1 1 Positive Genetic
ALP1 YNL270C Arginine transporter genetic 1 1 1 Negative Genetic
GRX8 YLR364W Glutaredoxin that employs a dithiol mechanism of catalysis genetic 1 1 1 Negative Genetic
ECM12 YHR021W-A Putative protein of unknown function genetic 1 1 1 Positive Genetic