Standard name Systematic name Name description Description
KOG1 YHR186C Subunit of TORC1 Subunit of TORC1; TORC1 is a rapamycin-sensitive complex involved in growth control that contains Tor1p or Tor2p, Lst8p and Tco89p; contains four HEAT repeats and seven WD-40 repeats; may act as a scaffold protein to couple TOR and its effectors
Visualize the interactome of KOG1
Links to external databases:
SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.460 0.647 0.770
ER 0.066 NaN NaN
Endosome 0.177 NaN NaN
Vac/Vac Memb 0.399 0.361 0.104
Mito NaN 0.088 0.311
Bud NaN NaN 0.052

GFP localization & abundance

GFP localization GFP abundance
vacuolar membrane low signal

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
KOG1 0 0 0 1 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
TOR1 YJR066W PIK-related protein kinase and rapamycin target physical 20 4 16 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Co-purification, Co-purification, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western
GTR1 YML121W Subunit of a TORC1-stimulating GTPase and the EGO/GSE complex physical 7 3 6 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western
TCO89 YPL180W Subunit of TORC1 (Tor1p or Tor2p-Kog1p-Lst8p-Tco89p) physical 5 3 5 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex
LST8 YNL006W Protein required for the transport of Gap1p physical 5 3 4 Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex
PIB2 YGL023C Phosphatidylinositol 3-phosphate binding protein physical 4 3 3 Affinity Capture-MS, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western
KSP1 YHR082C Serine/threonine protein kinase physical 4 2 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western
GTR2 YGR163W Subunit of a TORC1-stimulating GTPase and the EGO/GSE complex physical 3 3 2 Reconstituted Complex, Two-hybrid, Affinity Capture-Western
GTR2 YGR163W Subunit of a TORC1-stimulating GTPase and the EGO/GSE complex genetic 3 2 2 Dosage Rescue, Negative Genetic, Negative Genetic
MKS1 YNL076W Pleiotropic negative transcriptional regulator physical 3 2 2 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western
RHO1 YPR165W GTP-binding protein of the rho subfamily of Ras-like proteins physical 3 2 2 Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western
FBP1 YLR377C Fructose-1,6-bisphosphatase physical 3 2 2 Affinity Capture-Western, Affinity Capture-Western, Co-fractionation
GCN2 YDR283C Protein kinase physical 3 3 1 Affinity Capture-Western, Reconstituted Complex, Biochemical Activity
SDS22 YKL193C Regulatory subunit of the type 1 protein phosphatase (PP1) Glc7p physical 2 2 2 Affinity Capture-MS, Reconstituted Complex
UBI4 YLL039C Ubiquitin physical 2 2 2 Reconstituted Complex, Affinity Capture-Western
TOR2 YKL203C PIK-related protein kinase and rapamycin target physical 2 2 2 Affinity Capture-Western, Reconstituted Complex
PBP1 YGR178C Component of glucose deprivation induced stress granules physical 2 1 2 Affinity Capture-Western, Affinity Capture-Western
ZDS1 YMR273C Protein with a role in regulating Swe1p-dependent polarized growth genetic 2 1 2 Dosage Rescue, Dosage Rescue
KAP123 YER110C Karyopherin beta physical 2 2 1 Affinity Capture-MS, Affinity Capture-Western
UBA4 YHR111W E1-like protein that activates Urm1p before urmylation physical 2 2 1 Affinity Capture-MS, Affinity Capture-Western
TAP42 YMR028W Essential protein involved in the TOR signaling pathway physical 2 2 1 Affinity Capture-Western, Reconstituted Complex
HEF3 YNL014W Translational elongation factor EF-3 physical 2 2 1 Affinity Capture-MS, Affinity Capture-Western
BIM1 YER016W Microtubule plus end-tracking protein physical 2 2 1 Affinity Capture-MS, Affinity Capture-Western
BIK1 YCL029C Microtubule-associated protein physical 2 2 1 Affinity Capture-MS, Affinity Capture-Western
LST8 YNL006W Protein required for the transport of Gap1p genetic 2 1 1 Negative Genetic, Negative Genetic
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes physical 2 1 1 Affinity Capture-Western, Affinity Capture-Western
MAF1 YDR005C Highly conserved negative regulator of RNA polymerase III physical 2 1 1 Affinity Capture-Western, Affinity Capture-Western
TUP1 YCR084C General repressor of transcription in complex with Cyc8p physical 2 1 1 Two-hybrid, Two-hybrid
RTC1 YOL138C Subunit of SEACAT, a subcomplex of the SEA complex genetic 2 1 1 Synthetic Rescue, Synthetic Rescue
SGV1 YPR161C Cyclin (Bur2p)-dependent protein kinase genetic 2 1 1 Negative Genetic, Negative Genetic
MGA2 YIR033W ER membrane protein involved in regulation of OLE1 transcription genetic 2 1 1 Negative Genetic, Negative Genetic
MEH1 YKR007W Subunit of the EGO/GSE complex genetic 2 1 1 Negative Genetic, Negative Genetic
GTR1 YML121W Subunit of a TORC1-stimulating GTPase and the EGO/GSE complex genetic 2 1 1 Negative Genetic, Negative Genetic
IKS1 YJL057C Protein kinase of unknown cellular role genetic 2 1 1 Negative Genetic, Negative Genetic
CTF19 YPL018W Outer kinetochore protein, needed for accurate chromosome segregation physical 1 1 1 Two-hybrid
DSN1 YIR010W Essential component of the outer kinetochore MIND complex physical 1 1 1 Affinity Capture-MS
IKI3 YLR384C Subunit of Elongator complex genetic 1 1 1 Negative Genetic
FRT2 YAL028W Tail-anchored ER membrane protein of unknown function physical 1 1 1 Two-hybrid
CBC2 YPL178W Small subunit of the heterodimeric cap binding complex with Sto1p genetic 1 1 1 Negative Genetic
GCD11 YER025W Gamma subunit of the translation initiation factor eIF2 genetic 1 1 1 Negative Genetic
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 1 1 1 Negative Genetic
CFT2 YLR115W Subunit of the mRNA cleavage and polyadenlylation factor (CPF) genetic 1 1 1 Negative Genetic
AAH1 YNL141W Adenine deaminase (adenine aminohydrolase) genetic 1 1 1 Negative Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
ADE4 YMR300C Phosphoribosylpyrophosphate amidotransferase (PRPPAT) genetic 1 1 1 Negative Genetic
CDC3 YLR314C Component of the septin ring that is required for cytokinesis physical 1 1 1 Two-hybrid
BUD31 YCR063W Component of the SF3b subcomplex of the U2 snRNP genetic 1 1 1 Negative Genetic
CTK1 YKL139W Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) genetic 1 1 1 Negative Genetic
DCP2 YNL118C Catalytic subunit of Dcp1p-Dcp2p decapping enzyme complex physical 1 1 1 Two-hybrid
ECM1 YAL059W Pre-ribosomal factor involved in 60S ribosomal protein subunit export genetic 1 1 1 Positive Genetic
ELP2 YGR200C Subunit of Elongator complex genetic 1 1 1 Negative Genetic
FIP1 YJR093C Subunit of cleavage polyadenylation factor (CPF) genetic 1 1 1 Negative Genetic
FPR1 YNL135C Peptidyl-prolyl cis-trans isomerase (PPIase) physical 1 1 1 Affinity Capture-Western
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
CRM1 YGR218W Nuclear export factor, exportin physical 1 1 1 Affinity Capture-MS
COG3 YER157W Essential component of the conserved oligomeric Golgi complex genetic 1 1 1 Positive Genetic
FAB1 YFR019W 1-phosphatidylinositol-3-phosphate 5-kinase physical 1 1 1 PCA
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family genetic 1 1 1 Negative Genetic
HRR25 YPL204W Conserved casein kinase, monopolin subunit genetic 1 1 1 Negative Genetic
CCM1 YGR150C Mitochondrial 15S rRNA-binding protein physical 1 1 1 Two-hybrid
HDA2 YDR295C Subunit of HDA1 histone deacetylase complex physical 1 1 1 Two-hybrid
GIM3 YNL153C Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Negative Genetic
HMO1 YDR174W Chromatin associated high mobility group (HMG) family member genetic 1 1 1 Synthetic Lethality
IDH2 YOR136W Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase genetic 1 1 1 Negative Genetic
HTA1 YDR225W Histone H2A genetic 1 1 1 Positive Genetic
HOS4 YIL112W Subunit of the Set3 complex genetic 1 1 1 Negative Genetic
CCT6 YDR188W Subunit of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Negative Genetic
ATG9 YDL149W Transmembrane protein involved in forming Cvt and autophagic vesicles genetic 1 1 1 Negative Genetic
BCK1 YJL095W MAPKKK acting in the protein kinase C signaling pathway physical 1 1 1 Affinity Capture-MS
HEK2 YBL032W RNA binding protein involved in asymmetric localization of ASH1 mRNA physical 1 1 1 Affinity Capture-RNA
GET4 YOR164C Protein involved in inserting tail-anchored proteins into ER membranes genetic 1 1 1 Positive Genetic
ADR1 YDR216W Carbon source-responsive zinc-finger transcription factor genetic 1 1 1 Negative Genetic
IRA2 YOL081W GTPase-activating protein genetic 1 1 1 Positive Genetic
CAF20 YOR276W Phosphoprotein of the mRNA cap-binding complex physical 1 1 1 Affinity Capture-RNA
CDC5 YMR001C Polo-like kinase required for mitotic exit genetic 1 1 1 Dosage Rescue
AAC3 YBR085W Mitochondrial inner membrane ADP/ATP translocator genetic 1 1 1 Negative Genetic
IDH1 YNL037C Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase genetic 1 1 1 Negative Genetic
VPH2 YKL119C Integral membrane protein required for V-ATPase function physical 1 1 1 Affinity Capture-MS
TOR1 YJR066W PIK-related protein kinase and rapamycin target genetic 1 1 1 Negative Genetic
SCD6 YPR129W Repressor of translation initiation physical 1 1 1 Two-hybrid
LGE1 YPL055C Protein involved in histone H2B ubiquitination physical 1 1 1 Affinity Capture-MS
NPR1 YNL183C Protein kinase physical 1 1 1 Affinity Capture-MS
RTG3 YBL103C bHLH/Zip transcription factor for retrograde (RTG) and TOR pathways physical 1 1 1 Affinity Capture-MS
SAP185 YJL098W Protein that forms a complex with the Sit4p protein phosphatase physical 1 1 1 Affinity Capture-MS
SAP4 YGL229C Protein required for function of the Sit4p protein phosphatase physical 1 1 1 Affinity Capture-MS
NNK1 YKL171W Protein kinase physical 1 1 1 Affinity Capture-MS
MDH2 YOL126C Cytoplasmic malate dehydrogenase physical 1 1 1 Affinity Capture-Western
PCK1 YKR097W Phosphoenolpyruvate carboxykinase physical 1 1 1 Affinity Capture-Western
LAS17 YOR181W Actin assembly factor physical 1 1 1 Affinity Capture-MS
SSA2 YLL024C HSP70 family ATP-binding protein physical 1 1 1 Affinity Capture-MS
TIF1 YKR059W Translation initiation factor eIF4A physical 1 1 1 Affinity Capture-MS
TIF2 YJL138C Translation initiation factor eIF4A physical 1 1 1 Affinity Capture-MS
TEF1 YPR080W Translational elongation factor EF-1 alpha physical 1 1 1 Affinity Capture-MS
TEF2 YBR118W Translational elongation factor EF-1 alpha physical 1 1 1 Affinity Capture-MS
NPL3 YDR432W RNA-binding protein physical 1 1 1 Affinity Capture-MS
POP2 YNR052C Subunit of Ccr4-Not complex that mediates 3' to 5' mRNA deadenylation physical 1 1 1 Affinity Capture-MS
LSP1 YPL004C Eisosome core component physical 1 1 1 Affinity Capture-MS
PIL1 YGR086C Eisosome core component physical 1 1 1 Affinity Capture-MS
PAB1 YER165W Poly(A) binding protein physical 1 1 1 Affinity Capture-Western
YGR130C YGR130C Component of the eisosome with unknown function physical 1 1 1 Two-hybrid
SPC25 YER018C Component of the kinetochore-associated Ndc80 complex physical 1 1 1 Two-hybrid
MAD1 YGL086W Coiled-coil protein involved in spindle-assembly checkpoint physical 1 1 1 Two-hybrid
KOG1 YHR186C Subunit of TORC1 physical 1 1 1 Two-hybrid
SKN7 YHR206W Nuclear response regulator and transcription factor physical 1 1 1 Two-hybrid
NOT3 YIL038C Component of the CCR4-NOT core complex, involved in mRNA decapping physical 1 1 1 Two-hybrid
SPC42 YKL042W Central plaque component of spindle pole body (SPB) physical 1 1 1 Two-hybrid
STB2 YMR053C Protein that interacts with Sin3p in a two-hybrid assay physical 1 1 1 Two-hybrid
STV1 YMR054W Subunit a of the vacuolar-ATPase V0 domain physical 1 1 1 Two-hybrid
MRPS17 YMR188C Mitochondrial ribosomal protein of the small subunit physical 1 1 1 Two-hybrid
SPO21 YOL091W Component of the meiotic outer plaque of the spindle pole body physical 1 1 1 Two-hybrid
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p physical 1 1 1 Affinity Capture-MS
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p genetic 1 1 1 Negative Genetic
LAM6 YLR072W Sterol transporter that transfers sterols between membranes physical 1 1 1 Affinity Capture-MS
TMA46 YOR091W Protein of unknown function that associates with translating ribosomes physical 1 1 1 Affinity Capture-MS
RTC1 YOL138C Subunit of SEACAT, a subcomplex of the SEA complex physical 1 1 1 Affinity Capture-MS
PIB2 YGL023C Phosphatidylinositol 3-phosphate binding protein genetic 1 1 1 Negative Genetic
MPH1 YIR002C 3'-5' DNA helicase involved in error-free bypass of DNA lesions physical 1 1 1 Affinity Capture-MS
SRS2 YJL092W DNA helicase and DNA-dependent ATPase physical 1 1 1 Affinity Capture-MS
MTQ2 YDR140W S-adenosylmethionine-dependent methyltransferase physical 1 1 1 Affinity Capture-MS
RIM15 YFL033C Protein kinase involved in cell proliferation in response to nutrients genetic 1 1 1 Dosage Rescue
TIP41 YPR040W Tap42p-interacting protein genetic 1 1 1 Dosage Rescue
TTI1 YKL033W Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Negative Genetic
TEL2 YGR099W Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Negative Genetic
PRP8 YHR165C Component of U4/U6-U5 snRNP complex genetic 1 1 1 Phenotypic Enhancement
UTP9 YHR196W Nucleolar protein genetic 1 1 1 Phenotypic Enhancement
SCH9 YHR205W AGC family protein kinase genetic 1 1 1 Phenotypic Enhancement
PDC2 YDR081C Transcription factor for thiamine-regulated genes genetic 1 1 1 Positive Genetic
RAP1 YNL216W Essential DNA-binding transcription regulator that binds many loci genetic 1 1 1 Positive Genetic
YRO2 YBR054W Protein with a putative role in response to acid stress genetic 1 1 1 Positive Genetic
SPO23 YBR250W Protein of unknown function genetic 1 1 1 Positive Genetic
RVS161 YCR009C Amphiphysin-like lipid raft protein genetic 1 1 1 Positive Genetic
NUR1 YDL089W Protein involved in regulation of mitotic exit genetic 1 1 1 Positive Genetic
PMP3 YDR276C Small plasma membrane protein genetic 1 1 1 Positive Genetic
PFA5 YDR459C Palmitoyltransferase with autoacylation activity genetic 1 1 1 Positive Genetic
YER187W YER187W Putative protein of unknown function genetic 1 1 1 Positive Genetic
YBP2 YGL060W Central kinetochore associated protein genetic 1 1 1 Positive Genetic
VEL1 YGL258W Protein of unknown function genetic 1 1 1 Positive Genetic
MEP1 YGR121C Ammonium permease genetic 1 1 1 Positive Genetic
RPL14A YKL006W Ribosomal 60S subunit protein L14A genetic 1 1 1 Positive Genetic
MBR1 YKL093W Protein involved in mitochondrial functions and stress response genetic 1 1 1 Positive Genetic
RAD27 YKL113C 5' to 3' exonuclease, 5' flap endonuclease genetic 1 1 1 Positive Genetic
RPL8B YLL045C Ribosomal 60S subunit protein L8A genetic 1 1 1 Positive Genetic
URA4 YLR420W Dihydroorotase genetic 1 1 1 Positive Genetic
YML020W YML020W Putative protein of unknown function genetic 1 1 1 Positive Genetic
RAD14 YMR201C Subunit of Nucleotide Excision Repair Factor 1 (NEF1) genetic 1 1 1 Positive Genetic
SKY1 YMR216C SR protein kinase (SRPK) genetic 1 1 1 Positive Genetic
MTQ1 YNL063W S-adenosylmethionine-dependent methyltransferase genetic 1 1 1 Positive Genetic
RNH201 YNL072W Ribonuclease H2 catalytic subunit genetic 1 1 1 Positive Genetic
SIN3 YOL004W Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 1 1 1 Positive Genetic
MSH2 YOL090W Protein that binds to DNA mismatches genetic 1 1 1 Positive Genetic
RRP6 YOR001W Nuclear exosome exonuclease component genetic 1 1 1 Positive Genetic
VAM10 YOR068C Protein involved in vacuole morphogenesis genetic 1 1 1 Positive Genetic
VPS21 YOR089C Endosomal Rab family GTPase genetic 1 1 1 Positive Genetic
ULA1 YPL003W Protein that activates Rub1p (NEDD8) before neddylation genetic 1 1 1 Positive Genetic
RAD1 YPL022W Single-stranded DNA endonuclease (with Rad10p) genetic 1 1 1 Positive Genetic
RGL1 YPL066W Regulator of Rho1p signaling, cofactor of Tus1p genetic 1 1 1 Positive Genetic
SPP1 YPL138C Subunit of COMPASS (Set1C) genetic 1 1 1 Positive Genetic
LEA1 YPL213W Component of U2 snRNP complex genetic 1 1 1 Positive Genetic
SRO7 YPR032W Effector of Rab GTPase Sec4p genetic 1 1 1 Positive Genetic
MEP3 YPR138C Ammonium permease of high capacity and low affinity genetic 1 1 1 Positive Genetic
STU1 YBL034C Microtubule plus-end-tracking non-motor protein genetic 1 1 1 Negative Genetic
REB1 YBR049C RNA polymerase I enhancer binding protein genetic 1 1 1 Negative Genetic
ORC2 YBR060C Subunit of the origin recognition complex (ORC) genetic 1 1 1 Negative Genetic
MED8 YBR193C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
YCG1 YDR325W Subunit of the condensin complex genetic 1 1 1 Negative Genetic
PKC1 YBL105C Protein serine/threonine kinase genetic 1 1 1 Negative Genetic
PRP9 YDL030W Subunit of the SF3a splicing factor complex genetic 1 1 1 Negative Genetic
NSE4 YDL105W Component of the SMC5-SMC6 complex genetic 1 1 1 Negative Genetic
SEC7 YDR170C Guanine nucleotide exchange factor (GEF) for ADP ribosylation factors genetic 1 1 1 Negative Genetic
SNM1 YDR478W Ribonuclease MRP complex subunit genetic 1 1 1 Negative Genetic
PUP3 YER094C Beta 3 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
RSP5 YER125W NEDD4 family E3 ubiquitin ligase genetic 1 1 1 Negative Genetic
SEC4 YFL005W Rab family GTPase genetic 1 1 1 Negative Genetic
STT3 YGL022W Catalytic subunit of the oligosaccharyltransferase complex of the ER l genetic 1 1 1 Negative Genetic
MES1 YGR264C Methionyl-tRNA synthetase genetic 1 1 1 Negative Genetic
PRP19 YLL036C Splicing factor associated with the spliceosome genetic 1 1 1 Negative Genetic
SEC22 YLR268W R-SNARE protein genetic 1 1 1 Negative Genetic
TAD3 YLR316C Subunit of tRNA-specific adenosine-34 deaminase genetic 1 1 1 Negative Genetic
POB3 YML069W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) genetic 1 1 1 Negative Genetic
RSC9 YML127W Component of the RSC chromatin remodeling complex genetic 1 1 1 Negative Genetic
MCM1 YMR043W Transcription factor genetic 1 1 1 Negative Genetic
VTI1 YMR197C Protein involved in cis-Golgi membrane traffic genetic 1 1 1 Negative Genetic
OST2 YOR103C Epsilon subunit of the oligosaccharyltransferase complex genetic 1 1 1 Negative Genetic
MOT1 YPL082C Essential protein involved in regulation of transcription genetic 1 1 1 Negative Genetic
NAB3 YPL190C RNA-binding protein, subunit of Nrd1 complex (Nrd1p-Nab3p-Sen1p) genetic 1 1 1 Negative Genetic
TIF11 YMR260C Translation initiation factor eIF1A genetic 1 1 1 Negative Genetic
LDS1 YAL018C Protein Involved in spore wall assembly genetic 1 1 1 Negative Genetic
PIN4 YBL051C Protein involved in G2/M phase progression and response to DNA damage genetic 1 1 1 Negative Genetic
TPS1 YBR126C Synthase subunit of trehalose-6-P synthase/phosphatase complex genetic 1 1 1 Negative Genetic
SHE3 YBR130C Protein adaptor between Myo4p and the She2p-mRNA complex genetic 1 1 1 Negative Genetic
RPS6B YBR181C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
VAC17 YCL063W Phosphoprotein involved in vacuole inheritance genetic 1 1 1 Negative Genetic
SAT4 YCR008W Ser/Thr protein kinase involved in salt tolerance, nutrient response genetic 1 1 1 Negative Genetic
RIM1 YCR028C-A ssDNA-binding protein essential for mitochondrial genome maintenance genetic 1 1 1 Negative Genetic
THR4 YCR053W Threonine synthase genetic 1 1 1 Negative Genetic
PAT1 YCR077C Deadenylation-dependent mRNA-decapping factor genetic 1 1 1 Negative Genetic
PTC6 YCR079W Mitochondrial type 2C protein phosphatase (PP2C) genetic 1 1 1 Negative Genetic
PAR32 YDL173W Low complexity protein genetic 1 1 1 Negative Genetic
SNF3 YDL194W Plasma membrane low glucose sensor, regulates glucose transport genetic 1 1 1 Negative Genetic
OST4 YDL232W Subunit of the oligosaccharyltransferase complex of the ER lumen genetic 1 1 1 Negative Genetic
PST2 YDR032C FMN-dependent NAD(P)H:quinone oxidoreductase genetic 1 1 1 Negative Genetic
UBC13 YDR092W E2 ubiquitin-conjugating enzyme genetic 1 1 1 Negative Genetic
NBP2 YDR162C Protein involved in the HOG (high osmolarity glycerol) pathway genetic 1 1 1 Negative Genetic
STP1 YDR463W Transcription factor genetic 1 1 1 Negative Genetic
PUF6 YDR496C Pumilio-homology domain protein genetic 1 1 1 Negative Genetic
SNA2 YDR525W-A Protein of unknown function genetic 1 1 1 Negative Genetic
RPS24A YER074W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
RAD51 YER095W Strand exchange protein genetic 1 1 1 Negative Genetic
SLX8 YER116C Subunit of Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex genetic 1 1 1 Negative Genetic
YER134C YER134C Magnesium-dependent acid phosphatase genetic 1 1 1 Negative Genetic
YER158C YER158C Protein of unknown function genetic 1 1 1 Negative Genetic
SWP82 YFL049W Member of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Negative Genetic
MPC1 YGL080W Highly conserved subunit of mitochondrial pyruvate carrier (MPC) genetic 1 1 1 Negative Genetic
NCS6 YGL211W Protein required for uridine thiolation of Gln, Lys, and Glu tRNAs genetic 1 1 1 Negative Genetic
YGR050C YGR050C Protein of unknown function genetic 1 1 1 Negative Genetic
PAC10 YGR078C Part of the heteromeric co-chaperone GimC/prefoldin complex genetic 1 1 1 Negative Genetic
PRE9 YGR135W Alpha 3 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
TIM13 YGR181W Mitochondrial intermembrane space protein genetic 1 1 1 Negative Genetic
URM1 YIL008W Ubiquitin-like protein involved in thiolation of cytoplasmic tRNAs genetic 1 1 1 Negative Genetic
VPS53 YJL029C Component of the GARP (Golgi-associated retrograde protein) complex genetic 1 1 1 Negative Genetic
PEP8 YJL053W Vacuolar protein component of the retromer genetic 1 1 1 Negative Genetic
LSM1 YJL124C Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
RPS21B YJL136C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
VPS35 YJL154C Endosomal subunit of membrane-associated retromer complex genetic 1 1 1 Negative Genetic
LHS1 YKL073W Molecular chaperone of the endoplasmic reticulum lumen genetic 1 1 1 Negative Genetic
KTI12 YKL110C Protein that plays a role in modification of tRNA wobble nucleosides genetic 1 1 1 Negative Genetic
LST4 YKL176C Subunit of the Lst4p-Lst7p GTPase activating protein complex for Gtr2p genetic 1 1 1 Negative Genetic
RPS21A YKR057W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
SIS2 YKR072C Negative regulatory subunit of protein phosphatase 1 (Ppz1p) genetic 1 1 1 Negative Genetic
UBR2 YLR024C Cytoplasmic ubiquitin-protein ligase (E3) genetic 1 1 1 Negative Genetic
RPS0B YLR048W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
YLR053C YLR053C Putative protein of unknown function genetic 1 1 1 Negative Genetic
YKE2 YLR200W Subunit of the heterohexameric Gim/prefoldin protein complex genetic 1 1 1 Negative Genetic
VPS38 YLR360W Part of a Vps34p phosphatidylinositol 3-kinase complex genetic 1 1 1 Negative Genetic
SST2 YLR452C GTPase-activating protein for Gpa1p genetic 1 1 1 Negative Genetic
TMA23 YMR269W Nucleolar protein implicated in ribosome biogenesis genetic 1 1 1 Negative Genetic
RPS7B YNL096C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
NCS2 YNL119W Protein required for uridine thiolation of Lys(UUU) and Glu(UUC) tRNAs genetic 1 1 1 Negative Genetic
YNL134C YNL134C NADH-dependent aldehyde reductase genetic 1 1 1 Negative Genetic
YCK2 YNL154C Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform genetic 1 1 1 Negative Genetic
TLG2 YOL018C Syntaxin-like t-SNARE genetic 1 1 1 Negative Genetic
STI1 YOR027W Evolutionarily-conserved Hsp90 cochaperone genetic 1 1 1 Negative Genetic
VHS3 YOR054C Negative regulatory subunit of protein phosphatase 1 Ppz1p genetic 1 1 1 Negative Genetic
VAM3 YOR106W Syntaxin-like vacuolar t-SNARE genetic 1 1 1 Negative Genetic
YRM1 YOR172W Zinc finger transcription factor involved in multidrug resistance genetic 1 1 1 Negative Genetic
SER1 YOR184W 3-phosphoserine aminotransferase genetic 1 1 1 Negative Genetic
LIP5 YOR196C Protein involved in biosynthesis of the coenzyme lipoic acid genetic 1 1 1 Negative Genetic
RUD3 YOR216C Golgi matrix protein genetic 1 1 1 Negative Genetic
TUM1 YOR251C Rhodanese domain sulfur transferase genetic 1 1 1 Negative Genetic
SNC2 YOR327C Vesicle membrane receptor protein (v-SNARE) genetic 1 1 1 Negative Genetic
TRM44 YPL030W tRNA(Ser) Um(44) 2'-O-methyltransferase genetic 1 1 1 Negative Genetic
SSE1 YPL106C ATPase component of heat shock protein Hsp90 chaperone complex genetic 1 1 1 Negative Genetic
YPR063C YPR063C ER-localized protein of unknown function genetic 1 1 1 Negative Genetic
SPE3 YPR069C Spermidine synthase genetic 1 1 1 Negative Genetic
RPL23A YBL087C Ribosomal 60S subunit protein L23A genetic 1 1 1 Negative Genetic
SLM4 YBR077C Subunit of the EGO/GSE complex genetic 1 1 1 Negative Genetic
REI1 YBR267W Cytoplasmic pre-60S factor genetic 1 1 1 Negative Genetic
YDL199C YDL199C Putative transporter genetic 1 1 1 Negative Genetic
VAC8 YEL013W Vacuole-specific Myo2p receptor genetic 1 1 1 Negative Genetic
THO1 YER063W Conserved nuclear RNA-binding protein genetic 1 1 1 Negative Genetic
YFL041W-A YFL041W-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
PYC1 YGL062W Pyruvate carboxylase isoform genetic 1 1 1 Negative Genetic
YJL077W-B YJL077W-B Putative protein of unknown function genetic 1 1 1 Negative Genetic
PEX9 YMR018W Peroxisomal membrane signal receptor for peroxisomal matrix proteins genetic 1 1 1 Negative Genetic
PET494 YNR045W Mitochondrial translational activator specific for the COX3 mRNA genetic 1 1 1 Negative Genetic
MDM32 YOR147W Mitochondrial inner membrane protein with similarity to Mdm31p genetic 1 1 1 Negative Genetic
PPT2 YPL148C Phosphopantetheine:protein transferase (PPTase) genetic 1 1 1 Negative Genetic
STU2 YLR045C Microtubule polymerase of the XMAP215/Dis1 family genetic 1 1 1 Phenotypic Suppression
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 1 1 1 Negative Genetic
GET1 YGL020C Subunit of the GET complex genetic 1 1 1 Positive Genetic
DYN2 YDR424C Cytoplasmic light chain dynein, microtubule motor protein genetic 1 1 1 Negative Genetic
ERG10 YPL028W Acetyl-CoA C-acetyltransferase (acetoacetyl-CoA thiolase) genetic 1 1 1 Negative Genetic
ELM1 YKL048C Serine/threonine protein kinase genetic 1 1 1 Negative Genetic
ADH4 YGL256W Alcohol dehydrogenase isoenzyme type IV genetic 1 1 1 Negative Genetic
IPA1 YJR141W Protein implicated in pre-mRNA processing and proteasomal degradation genetic 1 1 1 Negative Genetic
HOM6 YJR139C Homoserine dehydrogenase (L-homoserine:NADP oxidoreductase) genetic 1 1 1 Negative Genetic
DSS4 YPR017C Guanine nucleotide dissociation stimulator for Sec4p genetic 1 1 1 Positive Genetic
GLE1 YDL207W Cytoplasmic nucleoporin required for polyadenylated mRNA export genetic 1 1 1 Negative Genetic
KIN2 YLR096W S/T protein kinase physical 1 1 1 Affinity Capture-MS
CBP6 YBR120C Mitochondrial protein required for translation of the COB mRNA genetic 1 1 1 Negative Genetic
DIA2 YOR080W Origin-binding F-box protein genetic 1 1 1 Negative Genetic
HOM3 YER052C Aspartate kinase (L-aspartate 4-P-transferase) genetic 1 1 1 Negative Genetic
HAL5 YJL165C Snf1p-related nutrient-responsive protein kinase genetic 1 1 1 Negative Genetic
CLB2 YPR119W B-type cyclin involved in cell cycle progression genetic 1 1 1 Dosage Rescue
DBF2 YGR092W Ser/Thr kinase involved in transcription and stress response genetic 1 1 1 Positive Genetic
BUB3 YOR026W Kinetochore checkpoint WD40 repeat protein physical 1 1 1 Reconstituted Complex
DUF1 YOL087C Ubiquitin-binding protein of unknown function genetic 1 1 1 Positive Genetic
HOM2 YDR158W Aspartic beta semi-aldehyde dehydrogenase genetic 1 1 1 Negative Genetic
FMP48 YGR052W Putative protein of unknown function physical 1 1 1 Affinity Capture-MS
IME2 YJL106W Serine/threonine protein kinase involved in activation of meiosis physical 1 1 1 Affinity Capture-MS
IME2 YJL106W Serine/threonine protein kinase involved in activation of meiosis genetic 1 1 1 Negative Genetic
ATG39 YLR312C Transmembrane receptor with a role in nucleophagy genetic 1 1 1 Negative Genetic
ELP6 YMR312W Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex genetic 1 1 1 Negative Genetic
ELP3 YPL086C Subunit of Elongator complex genetic 1 1 1 Negative Genetic
ELP4 YPL101W Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex genetic 1 1 1 Negative Genetic
CDC21 YOR074C Thymidylate synthase genetic 1 1 1 Positive Genetic
KAR3 YPR141C Minus-end-directed microtubule motor genetic 1 1 1 Negative Genetic
CCZ1 YBR131W Subunit of a heterodimeric guanine nucleotide exchange factor (GEF) genetic 1 1 1 Negative Genetic
IQG1 YPL242C Actin filament binding protein that enhances actin ring formation physical 1 1 1 Affinity Capture-Western
ABF1 YKL112W DNA binding protein with possible chromatin-reorganizing activity genetic 1 1 1 Negative Genetic
HMT1 YBR034C Nuclear SAM-dependent mono- and asymmetric methyltransferase genetic 1 1 1 Negative Genetic
GPR1 YDL035C Plasma membrane G protein coupled receptor (GPCR) genetic 1 1 1 Positive Genetic
IVY1 YDR229W Phospholipid-binding protein that interacts with both Ypt7p and Vps33p physical 1 1 1 Two-hybrid
CPR7 YJR032W Peptidyl-prolyl cis-trans isomerase (cyclophilin) genetic 1 1 1 Negative Genetic
AIM44 YPL158C Regulator of Cdc42p and Rho1p genetic 1 1 1 Negative Genetic
CRR1 YLR213C Putative glycoside hydrolase of the spore wall envelope genetic 1 1 1 Negative Genetic
HCM1 YCR065W Forkhead transcription factor genetic 1 1 1 Negative Genetic
HSP31 YDR533C Methylglyoxalase that converts methylglyoxal to D-lactate genetic 1 1 1 Negative Genetic
GTB1 YDR221W Glucosidase II beta subunit, forms a complex with alpha subunit Rot2p physical 1 1 1 Two-hybrid
JHD2 YJR119C JmjC domain family histone demethylase genetic 1 1 1 Positive Genetic
KEX1 YGL203C Cell death protease essential for hypochlorite-induced apoptosis genetic 1 1 1 Negative Genetic
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 1 1 1 Negative Genetic
ICL1 YER065C Isocitrate lyase physical 1 1 1 Affinity Capture-Western
FPR2 YDR519W Membrane-bound peptidyl-prolyl cis-trans isomerase (PPIase) genetic 1 1 1 Positive Genetic
IPF1 YDL176W Protein of unknown function involved in actin patch formation genetic 1 1 1 Positive Genetic
ATG33 YLR356W Mitochondrial mitophagy-specific protein genetic 1 1 1 Negative Genetic
AIM26 YKL037W Protein of unknown function genetic 1 1 1 Negative Genetic
IRC25 YLR021W Component of a heterodimeric Poc4p-Irc25p chaperone genetic 1 1 1 Negative Genetic
IGD1 YFR017C Cytoplasmic protein that inhibits Gdb1p glycogen debranching activity genetic 1 1 1 Positive Genetic
ARO2 YGL148W Bifunctional chorismate synthase and flavin reductase genetic 1 1 1 Negative Genetic
CAB1 YDR531W Pantothenate kinase, ATP:D-pantothenate 4'-phosphotransferase genetic 1 1 1 Negative Genetic
EOS1 YNL080C Protein involved in N-glycosylation genetic 1 1 1 Positive Genetic
DNF2 YDR093W Aminophospholipid translocase (flippase) genetic 1 1 1 Negative Genetic
JJJ3 YJR097W Iron-binding protein genetic 1 1 1 Negative Genetic
EAR1 YMR171C Specificity factor required for Rsp5p-dependent ubiquitination genetic 1 1 1 Negative Genetic
COX7 YMR256C Subunit VII of cytochrome c oxidase (Complex IV) genetic 1 1 1 Negative Genetic
CEM1 YER061C Mitochondrial beta-keto-acyl synthase genetic 1 1 1 Negative Genetic
HLJ1 YMR161W Co-chaperone for Hsp40p genetic 1 1 1 Negative Genetic
CHO2 YGR157W Phosphatidylethanolamine methyltransferase (PEMT) genetic 1 1 1 Negative Genetic
GIS3 YLR094C Protein of unknown function genetic 1 1 1 Dosage Rescue
CRS5 YOR031W Copper-binding metallothionein genetic 1 1 1 Negative Genetic
CRD1 YDL142C Cardiolipin synthase genetic 1 1 1 Positive Genetic
ATR2 YMR279C Putative boron transporter involved in boron efflux and resistance genetic 1 1 1 Negative Genetic
EFM2 YBR271W S-adenosylmethionine-dependent methyltransferase genetic 1 1 1 Positive Genetic
ICE2 YIL090W Integral ER membrane protein with type-III transmembrane domains genetic 1 1 1 Positive Genetic
AGP3 YFL055W Low-affinity amino acid permease genetic 1 1 1 Positive Genetic
ECM8 YBR076W Non-essential protein of unknown function genetic 1 1 1 Negative Genetic