Standard name Systematic name Name description Description
CDC21 YOR074C Thymidylate synthase Thymidylate synthase; required for de novo biosynthesis of pyrimidine deoxyribonucleotides; expression is induced at G1/S; human homolog TYMSOS can complement yeast cdc21 temperature-sensitive mutant at restrictive temperature
Visualize the interactome of CDC21
Links to external databases:
SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)
G1/S 46

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.944 0.963 0.957
Vac/Vac Memb 0.074 NaN NaN

GFP localization & abundance

GFP localization GFP abundance
cytoplasm, nucleus no data

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
CDC21 2 0 0 0 0

Enzyme information

Catalyzed reactions in Yeast8
r_1045 (thymidylate synthase)

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
FKH1 YIL131C Forkhead family transcription factor regulation 2 2 2 chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments
SWI6 YLR182W Transcription cofactor regulation 2 2 2 chromatin immunoprecipitation-chip evidence, S1 nuclease protection assay evidence
UNG1 YML021C Uracil-DNA glycosylase genetic 2 2 2 Synthetic Rescue, Negative Genetic
POL2 YNL262W Catalytic subunit of DNA polymerase (II) epsilon genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
DOT1 YDR440W Nucleosomal histone H3-Lys79 methylase genetic 2 1 2 Dosage Rescue, Dosage Rescue
RLF2 YPR018W Largest subunit (p90) of the Chromatin Assembly Complex (CAF-1) genetic 2 1 2 Dosage Rescue, Dosage Rescue
MAD1 YGL086W Coiled-coil protein involved in spindle-assembly checkpoint genetic 2 1 2 Negative Genetic, Negative Genetic
DCD1 YHR144C Deoxycytidine monophosphate (dCMP) deaminase genetic 2 1 2 Negative Genetic, Negative Genetic
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 2 1 2 Negative Genetic, Negative Genetic
ARP6 YLR085C Actin-related protein that binds nucleosomes genetic 2 1 2 Negative Genetic, Negative Genetic
CCT8 YJL008C Subunit of the cytosolic chaperonin Cct ring complex genetic 2 2 1 Positive Genetic, Negative Genetic
POL30 YBR088C Proliferating cell nuclear antigen (PCNA) genetic 2 2 1 Dosage Rescue, Synthetic Growth Defect
MEX67 YPL169C Poly(A)RNA binding protein involved in nuclear mRNA export genetic 2 2 1 Positive Genetic, Negative Genetic
DPA10 YLR307C-A Putative mitochondrial protein of unknown function genetic 2 2 1 Positive Genetic, Negative Genetic
MOG1 YJR074W Conserved nuclear protein that interacts with GTP-Gsp1p genetic 2 2 1 Negative Genetic, Positive Genetic
SPS4 YOR313C Protein whose expression is induced during sporulation genetic 2 2 1 Positive Genetic, Negative Genetic
TAP42 YMR028W Essential protein involved in the TOR signaling pathway genetic 2 2 1 Positive Genetic, Negative Genetic
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
FKH2 YNL068C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p) regulation 1 1 1 S1 nuclease protection assay evidence
GCN4 YEL009C bZIP transcriptional activator of amino acid biosynthetic genes regulation 1 1 1 DNA to cDNA expression microarray evidence
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes regulation 1 1 1 quantitative reverse transcription polymerase chain reaction evidence
MBP1 YDL056W Transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
BRR2 YER172C RNA-dependent ATPase RNA helicase (DEIH box) genetic 1 1 1 Negative Genetic
ARX1 YDR101C Nuclear export factor for the ribosomal pre-60S subunit genetic 1 1 1 Negative Genetic
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 1 1 1 Negative Genetic
ARP3 YJR065C Essential component of the Arp2/3 complex genetic 1 1 1 Positive Genetic
BEM2 YER155C Rho GTPase activating protein (RhoGAP) genetic 1 1 1 Negative Genetic
CDC12 YHR107C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Negative Genetic
CDC13 YDL220C Single stranded DNA-binding protein found at TG1-3 telomere G-tails genetic 1 1 1 Negative Genetic
AKL1 YBR059C Ser/Thr protein kinase genetic 1 1 1 Negative Genetic
ADH4 YGL256W Alcohol dehydrogenase isoenzyme type IV genetic 1 1 1 Negative Genetic
AIM46 YHR199C Protein of unknown function genetic 1 1 1 Negative Genetic
CDC123 YLR215C Assembly factor for the eIF2 translation initiation factor complex genetic 1 1 1 Negative Genetic
ALD5 YER073W Mitochondrial aldehyde dehydrogenase genetic 1 1 1 Negative Genetic
BIM1 YER016W Microtubule plus end-tracking protein genetic 1 1 1 Negative Genetic
BOS1 YLR078C v-SNARE (vesicle specific SNAP receptor) genetic 1 1 1 Negative Genetic
RTF1 YGL244W Subunit of RNAPII-associated chromatin remodeling Paf1 complex physical 1 1 1 Affinity Capture-MS
GTT2 YLL060C Glutathione S-transferase capable of homodimerization physical 1 1 1 Affinity Capture-MS
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
TCA17 YEL048C Component of transport protein particle (TRAPP) complex II physical 1 1 1 Affinity Capture-MS
GIS2 YNL255C Translational activator for mRNAs with internal ribosome entry sites physical 1 1 1 Affinity Capture-RNA
SLF1 YDR515W RNA binding protein that associates with polysomes physical 1 1 1 Affinity Capture-RNA
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
SAC6 YDR129C Fimbrin, actin-bundling protein genetic 1 1 1 Phenotypic Enhancement
CDC73 YLR418C Component of the Paf1p complex genetic 1 1 1 Synthetic Lethality
TEL2 YGR099W Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Negative Genetic
RFT1 YBL020W Membrane protein required for translocation of Man5GlcNac2-PP-Dol genetic 1 1 1 Positive Genetic
PKC1 YBL105C Protein serine/threonine kinase genetic 1 1 1 Positive Genetic
RER2 YBR002C Forms the dehydrodolichyl diphosphate synthase (DDS) complex with NUS1 genetic 1 1 1 Positive Genetic
MAK5 YBR142W Essential nucleolar protein genetic 1 1 1 Positive Genetic
CDC36 YDL165W Component of the CCR4-NOT core complex, involved in mRNA decapping genetic 1 1 1 Positive Genetic
YRA1 YDR381W Nuclear polyadenylated RNA-binding protein genetic 1 1 1 Positive Genetic
HYP2 YEL034W Translation elongation factor eIF-5A genetic 1 1 1 Positive Genetic
UTR5 YEL035C Protein of unknown function genetic 1 1 1 Positive Genetic
POL5 YEL055C Protein involved in 60S assembly and pre-40S AFs recycling genetic 1 1 1 Positive Genetic
SPB4 YFL002C Putative ATP-dependent RNA helicase genetic 1 1 1 Positive Genetic
CDC4 YFL009W F-box protein required for both the G1/S and G2/M phase transitions genetic 1 1 1 Positive Genetic
OLE1 YGL055W Delta(9) fatty acid desaturase genetic 1 1 1 Positive Genetic
SRM1 YGL097W Nucleotide exchange factor for Gsp1p genetic 1 1 1 Positive Genetic
USE1 YGL098W Essential SNARE protein localized to the ER genetic 1 1 1 Positive Genetic
RPL28 YGL103W Ribosomal 60S subunit protein L28 genetic 1 1 1 Positive Genetic
RPS2 YGL123W Protein component of the small (40S) subunit genetic 1 1 1 Positive Genetic
UTP8 YGR128C Nucleolar protein required for export of tRNAs from the nucleus genetic 1 1 1 Positive Genetic
NOP19 YGR251W Ribosome biogenesis factor genetic 1 1 1 Positive Genetic
KOG1 YHR186C Subunit of TORC1 genetic 1 1 1 Positive Genetic
YJU2 YKL095W Essential protein required for pre-mRNA splicing genetic 1 1 1 Positive Genetic
MTR2 YKL186C mRNA transport regulator genetic 1 1 1 Positive Genetic
RLP24 YLR009W Essential protein required for ribosomal large subunit biogenesis genetic 1 1 1 Positive Genetic
RPL10 YLR075W Ribosomal 60S subunit protein L10 genetic 1 1 1 Positive Genetic
GPN3 YLR243W Putative GTPase with a role in biogenesis of RNA pol II and polIII genetic 1 1 1 Positive Genetic
SMD2 YLR275W Core Sm protein Sm D2 genetic 1 1 1 Positive Genetic
PBR1 YNL181W Putative oxidoreductase genetic 1 1 1 Positive Genetic
NAR1 YNL240C Subunit of the cytosolic iron-sulfur (FeS) protein assembly machinery genetic 1 1 1 Positive Genetic
CWC25 YNL245C Splicing factor required for the first step of pre-mRNA splicing genetic 1 1 1 Positive Genetic
DCP1 YOL149W Subunit of the Dcp1p-Dcp2p decapping enzyme complex genetic 1 1 1 Positive Genetic
HSH49 YOR319W U2-snRNP associated splicing factor genetic 1 1 1 Positive Genetic
RPL33A YPL143W Ribosomal 60S subunit protein L33A genetic 1 1 1 Positive Genetic
PRP46 YPL151C Member of the NineTeen Complex (NTC) genetic 1 1 1 Positive Genetic
NSL1 YPL233W Essential component of the MIND kinetochore complex genetic 1 1 1 Positive Genetic
FHL1 YPR104C Regulator of ribosomal protein (RP) transcription genetic 1 1 1 Positive Genetic
MRD1 YPR112C Essential conserved small ribosomal subunit (40s) synthesis factor genetic 1 1 1 Positive Genetic
SMX3 YPR182W Core Sm protein Sm F genetic 1 1 1 Positive Genetic
PAU8 YAL068C Protein of unknown function genetic 1 1 1 Positive Genetic
YBR137W YBR137W Protein with a role in ER delivery of tail-anchored membrane proteins genetic 1 1 1 Positive Genetic
HNT1 YDL125C Adenosine 5'-monophosphoramidase genetic 1 1 1 Positive Genetic
YDR034C-A YDR034C-A Putative protein of unknown function genetic 1 1 1 Positive Genetic
SSD1 YDR293C Translational repressor genetic 1 1 1 Positive Genetic
CTS2 YDR371W Putative chitinase genetic 1 1 1 Positive Genetic
VMA8 YEL051W Subunit D of the V1 peripheral membrane domain of V-ATPase genetic 1 1 1 Positive Genetic
YGL006W-A YGL006W-A Putative protein of unknown function genetic 1 1 1 Positive Genetic
TIF4632 YGL049C Translation initiation factor eIF4G and scaffold protein genetic 1 1 1 Positive Genetic
MUP1 YGR055W High affinity methionine permease genetic 1 1 1 Positive Genetic
YGR067C YGR067C Putative protein of unknown function genetic 1 1 1 Positive Genetic
YGR204C-A YGR204C-A Putative protein of unknown function genetic 1 1 1 Positive Genetic
TOM71 YHR117W Mitochondrial outer membrane protein genetic 1 1 1 Positive Genetic
NRE1 YIR035C Putative cytoplasmic short-chain dehydrogenase/reductase genetic 1 1 1 Positive Genetic
MHO1 YJR008W Protein of unknown function genetic 1 1 1 Positive Genetic
TGL1 YKL140W Steryl ester hydrolase genetic 1 1 1 Positive Genetic
MCH2 YKL221W Protein with similarity to mammalian monocarboxylate permeases genetic 1 1 1 Positive Genetic
YMD8 YML038C Putative nucleotide sugar transporter genetic 1 1 1 Positive Genetic
VPS71 YML041C Nucleosome-binding component of the SWR1 complex genetic 1 1 1 Positive Genetic
NAB6 YML117W Putative RNA-binding protein genetic 1 1 1 Positive Genetic
SIP3 YNL257C Putative sterol transfer protein genetic 1 1 1 Positive Genetic
PRS5 YOL061W 5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase genetic 1 1 1 Positive Genetic
RDS2 YPL133C Transcription factor involved in regulating gluconeogenesis genetic 1 1 1 Positive Genetic
FUM1 YPL262W Fumarase genetic 1 1 1 Positive Genetic
CDC27 YBL084C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Negative Genetic
GPI18 YBR004C Functional ortholog of human PIG-V genetic 1 1 1 Negative Genetic
ORC2 YBR060C Subunit of the origin recognition complex (ORC) genetic 1 1 1 Negative Genetic
CMD1 YBR109C Calmodulin genetic 1 1 1 Negative Genetic
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit genetic 1 1 1 Negative Genetic
TRS20 YBR254C Core component of transport protein particle (TRAPP) complexes I-III genetic 1 1 1 Negative Genetic
CTR86 YCR054C Essential protein of unknown function genetic 1 1 1 Negative Genetic
MPS1 YDL028C Dual-specificity kinase genetic 1 1 1 Negative Genetic
PRP9 YDL030W Subunit of the SF3a splicing factor complex genetic 1 1 1 Negative Genetic
NSE4 YDL105W Component of the SMC5-SMC6 complex genetic 1 1 1 Negative Genetic
COP1 YDL145C Alpha subunit of COPI vesicle coatomer complex genetic 1 1 1 Negative Genetic
PSF1 YDR013W Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p) genetic 1 1 1 Negative Genetic
KRS1 YDR037W Lysyl-tRNA synthetase genetic 1 1 1 Negative Genetic
HEM13 YDR044W Coproporphyrinogen III oxidase genetic 1 1 1 Negative Genetic
SLU7 YDR088C RNA splicing factor genetic 1 1 1 Negative Genetic
PDS1 YDR113C Securin genetic 1 1 1 Negative Genetic
TAF10 YDR167W Subunit (145 kDa) of TFIID and SAGA complexes genetic 1 1 1 Negative Genetic
SUP35 YDR172W Translation termination factor eRF3 genetic 1 1 1 Negative Genetic
RVB1 YDR190C ATP-dependent DNA helicase, also known as pontin genetic 1 1 1 Negative Genetic
SPC19 YDR201W Essential subunit of the Dam1 complex (aka DASH complex) genetic 1 1 1 Negative Genetic
NSE3 YDR288W Component of the SMC5-SMC6 complex genetic 1 1 1 Negative Genetic
CFT1 YDR301W RNA-binding subunit of the mRNA cleavage and polyadenylation factor genetic 1 1 1 Negative Genetic
RSC3 YDR303C Component of the RSC chromatin remodeling complex genetic 1 1 1 Negative Genetic
SRB7 YDR308C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
UTP4 YDR324C Subunit of U3-containing 90S preribosome and SSU processome complexes genetic 1 1 1 Negative Genetic
YCG1 YDR325W Subunit of the condensin complex genetic 1 1 1 Negative Genetic
YDR341C YDR341C Arginyl-tRNA synthetase genetic 1 1 1 Negative Genetic
NCB2 YDR397C Subunit of a heterodimeric NC2 transcription regulator complex genetic 1 1 1 Negative Genetic
SLD5 YDR489W Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p) genetic 1 1 1 Negative Genetic
MCM3 YEL032W Protein involved in DNA replication genetic 1 1 1 Negative Genetic
SPC25 YER018C Component of the kinetochore-associated Ndc80 complex genetic 1 1 1 Negative Genetic
GDI1 YER136W GDP dissociation inhibitor genetic 1 1 1 Negative Genetic
SCC4 YER147C Subunit of cohesin loading factor (Scc2p-Scc4p) genetic 1 1 1 Negative Genetic
COG3 YER157W Essential component of the conserved oligomeric Golgi complex genetic 1 1 1 Negative Genetic
PAB1 YER165W Poly(A) binding protein genetic 1 1 1 Negative Genetic
GNA1 YFL017C Glucosamine-6-phosphate acetyltransferase genetic 1 1 1 Negative Genetic
MOB2 YFL034C-B Activator of Cbk1p kinase genetic 1 1 1 Negative Genetic
YPT1 YFL038C Rab family GTPase genetic 1 1 1 Negative Genetic
SCL1 YGL011C Alpha 1 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
CEG1 YGL130W Guanylyltransferase involved in mRNA 5' capping genetic 1 1 1 Negative Genetic
SEC27 YGL137W Essential beta'-coat protein of the COPI coatomer genetic 1 1 1 Negative Genetic
MCM6 YGL201C Protein involved in DNA replication genetic 1 1 1 Negative Genetic
TAM41 YGR046W Mitochondrial phosphatidate cytidylyltransferase (CDP-DAG synthase) genetic 1 1 1 Negative Genetic
DBF2 YGR092W Ser/Thr kinase involved in transcription and stress response genetic 1 1 1 Negative Genetic
PTI1 YGR156W Essential component of CPF (cleavage and polyadenylation factor) genetic 1 1 1 Negative Genetic
YIP1 YGR172C Integral membrane protein genetic 1 1 1 Negative Genetic
ERG11 YHR007C Lanosterol 14-alpha-demethylase genetic 1 1 1 Negative Genetic
RPP1 YHR062C Subunit of both RNase MRP and nuclear RNase P genetic 1 1 1 Negative Genetic
DYS1 YHR068W Deoxyhypusine synthase genetic 1 1 1 Negative Genetic
ERG7 YHR072W Lanosterol synthase genetic 1 1 1 Negative Genetic
TAO3 YIL129C Component of the RAM signaling network genetic 1 1 1 Negative Genetic
SLN1 YIL147C Transmembrane histidine phosphotransfer kinase and osmosensor genetic 1 1 1 Negative Genetic
TIM54 YJL054W Component of the mitochondrial TIM22 complex genetic 1 1 1 Negative Genetic
PSF2 YJL072C Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p) genetic 1 1 1 Negative Genetic
DPB11 YJL090C DNA replication initiation protein genetic 1 1 1 Negative Genetic
ESS1 YJR017C Peptidylprolyl-cis/trans-isomerase (PPIase) genetic 1 1 1 Negative Genetic
SSC1 YJR045C Hsp70 family ATPase genetic 1 1 1 Negative Genetic
CDC8 YJR057W Nucleoside monophosphate and nucleoside diphosphate kinase genetic 1 1 1 Negative Genetic
FIP1 YJR093C Subunit of cleavage polyadenylation factor (CPF) genetic 1 1 1 Negative Genetic
UBA1 YKL210W Ubiquitin activating enzyme (E1) genetic 1 1 1 Negative Genetic
ORC3 YLL004W Subunit of the origin recognition complex (ORC) genetic 1 1 1 Negative Genetic
GPI13 YLL031C ER membrane localized phosphoryltransferase genetic 1 1 1 Negative Genetic
STU2 YLR045C Microtubule polymerase of the XMAP215/Dis1 family genetic 1 1 1 Negative Genetic
GAA1 YLR088W Subunit of the GPI:protein transamidase complex genetic 1 1 1 Negative Genetic
CDC45 YLR103C DNA replication initiation factor genetic 1 1 1 Negative Genetic
SEC22 YLR268W R-SNARE protein genetic 1 1 1 Negative Genetic
STT4 YLR305C Phosphatidylinositol-4-kinase genetic 1 1 1 Negative Genetic
CDC3 YLR314C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Negative Genetic
SFH1 YLR321C Component of the RSC chromatin remodeling complex genetic 1 1 1 Negative Genetic
CWC24 YLR323C General splicing factor genetic 1 1 1 Negative Genetic
GAB1 YLR459W Subunit of the glycosylphosphatidylinositol transamidase complex genetic 1 1 1 Negative Genetic
TAF11 YML015C TFIID subunit (40 kDa) genetic 1 1 1 Negative Genetic
NSE5 YML023C Component of the SMC5-SMC6 complex genetic 1 1 1 Negative Genetic
RSE1 YML049C Protein involved in pre-mRNA splicing genetic 1 1 1 Negative Genetic
SEC65 YML105C Subunit of the signal recognition particle (SRP) genetic 1 1 1 Negative Genetic
TAF8 YML114C TFIID subunit (65 kDa) genetic 1 1 1 Negative Genetic
ERG13 YML126C 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) synthase genetic 1 1 1 Negative Genetic
RNA14 YMR061W Component of the cleavage and polyadenylation factor I (CF I) genetic 1 1 1 Negative Genetic
SPC24 YMR117C Component of the kinetochore-associated Ndc80 complex genetic 1 1 1 Negative Genetic
NIP1 YMR309C eIF3c subunit of the eukaryotic translation initiation factor 3 (eIF3) genetic 1 1 1 Negative Genetic
GPI15 YNL038W Protein involved in the synthesis of GlcNAc-PI genetic 1 1 1 Negative Genetic
POL1 YNL102W Catalytic subunit of the DNA polymerase I alpha-primase complex genetic 1 1 1 Negative Genetic
DBP2 YNL112W ATP-dependent RNA helicase of the DEAD-box protein family genetic 1 1 1 Negative Genetic
DCP2 YNL118C Catalytic subunit of Dcp1p-Dcp2p decapping enzyme complex genetic 1 1 1 Negative Genetic
SPC98 YNL126W Component of the microtubule-nucleating Tub4p (gamma-tubulin) complex genetic 1 1 1 Negative Genetic
KRE33 YNL132W Acetyltransferase required for biogenesis of small ribosomal subunit genetic 1 1 1 Negative Genetic
POP1 YNL221C Subunit of RNase MRP, nuclear RNase P and telomerase complexes genetic 1 1 1 Negative Genetic
SSU72 YNL222W Phosphatase and transcription/RNA-processing factor genetic 1 1 1 Negative Genetic
POP3 YNL282W Subunit of both RNase MRP and nuclear RNase P genetic 1 1 1 Negative Genetic
SEC12 YNR026C Guanine nucleotide exchange factor (GEF) genetic 1 1 1 Negative Genetic
MVD1 YNR043W Mevalonate pyrophosphate decarboxylase genetic 1 1 1 Negative Genetic
RFC1 YOR217W Subunit of heteropentameric Replication factor C (RF-C) genetic 1 1 1 Negative Genetic
MRS6 YOR370C Rab escort protein genetic 1 1 1 Negative Genetic
TFC8 YPL007C Subunit of RNA polymerase III transcription initiation factor complex genetic 1 1 1 Negative Genetic
ULP1 YPL020C Protease that specifically cleaves Smt3p protein conjugates genetic 1 1 1 Negative Genetic
TFB2 YPL122C Subunit of TFIIH and nucleotide excision repair factor 3 complexes genetic 1 1 1 Negative Genetic
SPC29 YPL124W Inner plaque spindle pole body (SPB) component genetic 1 1 1 Negative Genetic
RAD53 YPL153C DNA damage response kinase genetic 1 1 1 Negative Genetic
IPL1 YPL209C Aurora kinase of chromosomal passenger complex genetic 1 1 1 Negative Genetic
TIF6 YPR016C Constituent of 66S pre-ribosomal particles genetic 1 1 1 Negative Genetic
ORC4 YPR162C Subunit of the origin recognition complex (ORC) genetic 1 1 1 Negative Genetic
DPM1 YPR183W Dolichol phosphate mannose (Dol-P-Man) synthase of ER membrane genetic 1 1 1 Negative Genetic
FUN26 YAL022C High affinity, broad selectivity, nucleoside/nucleobase transporter genetic 1 1 1 Negative Genetic
YAR029W YAR029W Member of DUP240 gene family but contains no transmembrane domains genetic 1 1 1 Negative Genetic
PRM9 YAR031W Pheromone-regulated protein genetic 1 1 1 Negative Genetic
YAR066W YAR066W Putative GPI protein genetic 1 1 1 Negative Genetic
SHE1 YBL031W Mitotic spindle protein genetic 1 1 1 Negative Genetic
PET112 YBL080C Subunit of the trimeric GatFAB AmidoTransferase(AdT) complex genetic 1 1 1 Negative Genetic
YBL100W-C YBL100W-C Putative protein of unknown function genetic 1 1 1 Negative Genetic
SIF2 YBR103W WD40 repeat-containing subunit of Set3C histone deacetylase complex genetic 1 1 1 Negative Genetic
SUS1 YBR111W-A Global transcriptional regulator, component of SAGA, TREX-2 complexes genetic 1 1 1 Negative Genetic
YBR184W YBR184W Putative protein of unknown function genetic 1 1 1 Negative Genetic
YBR221W-A YBR221W-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
YBR238C YBR238C Mitochondrial membrane protein genetic 1 1 1 Negative Genetic
VVS1 YBR241C Putative transporter, member of the sugar porter family genetic 1 1 1 Negative Genetic
MIC12 YBR262C Component of the MICOS complex genetic 1 1 1 Negative Genetic
PHO89 YBR296C Plasma membrane Na+/Pi cotransporter genetic 1 1 1 Negative Genetic
MAL32 YBR299W Maltase (alpha-D-glucosidase) genetic 1 1 1 Negative Genetic
LDB16 YCL005W Protein involved in lipid droplet (LD) assembly genetic 1 1 1 Negative Genetic
MIC10 YCL057C-A Conserved component of the MICOS complex genetic 1 1 1 Negative Genetic
YIH1 YCR059C Negative regulator of eIF2 kinase Gcn2p genetic 1 1 1 Negative Genetic
EGO2 YCR075W-A Subunit of the EGO/GSE complex genetic 1 1 1 Negative Genetic
PTC1 YDL006W Type 2C protein phosphatase (PP2C) genetic 1 1 1 Negative Genetic
KNH1 YDL049C Protein with similarity to Kre9p genetic 1 1 1 Negative Genetic
SYO1 YDL063C Transport adaptor or symportin genetic 1 1 1 Negative Genetic
PMT5 YDL093W Protein O-mannosyltransferase genetic 1 1 1 Negative Genetic
CRD1 YDL142C Cardiolipin synthase genetic 1 1 1 Negative Genetic
YDL157C YDL157C Putative protein of unknown function genetic 1 1 1 Negative Genetic
SNF3 YDL194W Plasma membrane low glucose sensor, regulates glucose transport genetic 1 1 1 Negative Genetic
SHS1 YDL225W Component of the septin ring that is required for cytokinesis genetic 1 1 1 Negative Genetic
COS7 YDL248W Endosomal protein involved in turnover of plasma membrane proteins genetic 1 1 1 Negative Genetic
GCV1 YDR019C T subunit of the mitochondrial glycine decarboxylase complex genetic 1 1 1 Negative Genetic
RRG1 YDR065W Protein of unknown function genetic 1 1 1 Negative Genetic
NBP2 YDR162C Protein involved in the HOG (high osmolarity glycerol) pathway genetic 1 1 1 Negative Genetic
YDR248C YDR248C Putative gluconokinase genetic 1 1 1 Negative Genetic
EXG2 YDR261C Exo-1,3-beta-glucanase genetic 1 1 1 Negative Genetic
HNT2 YDR305C Dinucleoside triphosphate hydrolase genetic 1 1 1 Negative Genetic
PFU1 YDR306C F-box protein that regulates pheromone-dependent morphogenesis genetic 1 1 1 Negative Genetic
PMT7 YDR307W Putative protein mannosyltransferase similar to Pmt1p genetic 1 1 1 Negative Genetic
IPK1 YDR315C Inositol 1,3,4,5,6-pentakisphosphate 2-kinase genetic 1 1 1 Negative Genetic
MRX8 YDR336W Protein that associates with mitochondrial ribosome genetic 1 1 1 Negative Genetic
SPT3 YDR392W Subunit of the SAGA and SAGA-like transcriptional regulatory complexes genetic 1 1 1 Negative Genetic
SIZ1 YDR409W SUMO E3 ligase genetic 1 1 1 Negative Genetic
VPS72 YDR485C Htz1p-binding component of the SWR1 complex genetic 1 1 1 Negative Genetic
EMI2 YDR516C Hexokinase expressed during growth with low glucose levels genetic 1 1 1 Negative Genetic
PXP1 YEL020C Peroxisomal matrix protein genetic 1 1 1 Negative Genetic
SPF1 YEL031W P-type ATPase, ion transporter of the ER membrane genetic 1 1 1 Negative Genetic
YEL073C YEL073C Putative protein of unknown function genetic 1 1 1 Negative Genetic
SAP1 YER047C Putative ATPase of the AAA family genetic 1 1 1 Negative Genetic
PRS2 YER099C 5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase genetic 1 1 1 Negative Genetic
UBC6 YER100W Ubiquitin-conjugating enzyme involved in ERAD genetic 1 1 1 Negative Genetic
COX15 YER141W Heme a synthase genetic 1 1 1 Negative Genetic
YER175W-A YER175W-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
FMP32 YFL046W Regulator of mitochondrial proline metabolism genetic 1 1 1 Negative Genetic
THI5 YFL058W Protein involved in synthesis of the thiamine precursor HMP genetic 1 1 1 Negative Genetic
CNN1 YFR046C Kinetochore protein genetic 1 1 1 Negative Genetic
YGL041C-B YGL041C-B Putative protein of unknown function genetic 1 1 1 Negative Genetic
TYW3 YGL050W tRNA methyltransferase required for synthesis of wybutosine genetic 1 1 1 Negative Genetic
GEP7 YGL057C Protein of unknown function genetic 1 1 1 Negative Genetic
SGF73 YGL066W Subunit of DUBm module of SAGA and SLIK genetic 1 1 1 Negative Genetic
LIF1 YGL090W Component of the DNA ligase IV complex genetic 1 1 1 Negative Genetic
FLC3 YGL139W Putative FAD transporter, similar to Flc1p and Flc2p genetic 1 1 1 Negative Genetic
ROG1 YGL144C Lipase with specificity for monoacylglycerol genetic 1 1 1 Negative Genetic
RPL9A YGL147C Ribosomal 60S subunit protein L9A genetic 1 1 1 Negative Genetic
SIP2 YGL208W One of three alternate beta subunits of the Snf1 kinase complex genetic 1 1 1 Negative Genetic
MIG2 YGL209W Zinc finger transcriptional repressor genetic 1 1 1 Negative Genetic
MTC3 YGL226W Protein of unknown function genetic 1 1 1 Negative Genetic
MTO1 YGL236C Mitochondrial protein genetic 1 1 1 Negative Genetic
MRPL25 YGR076C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
PCP1 YGR101W Mitochondrial serine protease genetic 1 1 1 Negative Genetic
YGR117C YGR117C Putative protein of unknown function genetic 1 1 1 Negative Genetic
YGR121W-A YGR121W-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
YGR146C-A YGR146C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
TRS65 YGR166W Component of transport protein particle (TRAPP) complex II genetic 1 1 1 Negative Genetic
RNR4 YGR180C Ribonucleotide-diphosphate reductase (RNR) small subunit genetic 1 1 1 Negative Genetic
PEX21 YGR239C Peroxin required for peroxisomal matrix protein targeting genetic 1 1 1 Negative Genetic
SLH1 YGR271W Subunit of ribosome-associated quality control trigger complex (RQT) genetic 1 1 1 Negative Genetic
VPS29 YHR012W Subunit of the membrane-associated retromer complex genetic 1 1 1 Negative Genetic
RRM3 YHR031C DNA helicase involved in rDNA replication and Ty1 transposition genetic 1 1 1 Negative Genetic
SET1 YHR119W Histone methyltransferase, subunit of the COMPASS (Set1C) complex genetic 1 1 1 Negative Genetic
REC104 YHR157W Protein involved in early stages of meiotic recombination genetic 1 1 1 Negative Genetic
PPX1 YHR201C Exopolyphosphatase genetic 1 1 1 Negative Genetic
IMD2 YHR216W Inosine monophosphate dehydrogenase genetic 1 1 1 Negative Genetic
YHR218W YHR218W Helicase-like protein encoded within the telomeric Y' element genetic 1 1 1 Negative Genetic
TED1 YIL039W GPI-glycan remodelase genetic 1 1 1 Negative Genetic
FIS1 YIL065C Protein involved in mitochondrial fission and peroxisome abundance genetic 1 1 1 Negative Genetic
MPH1 YIR002C 3'-5' DNA helicase involved in error-free bypass of DNA lesions genetic 1 1 1 Negative Genetic
DAL81 YIR023W Positive regulator of genes in multiple nitrogen degradation pathways genetic 1 1 1 Negative Genetic
SYS1 YJL004C Integral membrane protein of the Golgi genetic 1 1 1 Negative Genetic
CHM7 YJL049W Yeast homolog of human CHMP7, localizes to the endoplasmic reticulum genetic 1 1 1 Negative Genetic
IRC8 YJL051W Bud tip localized protein of unknown function genetic 1 1 1 Negative Genetic
YJL052C-A YJL052C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
KHA1 YJL094C Putative K+/H+ antiporter genetic 1 1 1 Negative Genetic
IDS2 YJL146W Protein involved in modulation of Ime2p activity during meiosis genetic 1 1 1 Negative Genetic
ISY1 YJR050W Member of the NineTeen Complex (NTC) genetic 1 1 1 Negative Genetic
STR2 YJR130C Cystathionine gamma-synthase, converts cysteine into cystathionine genetic 1 1 1 Negative Genetic
HIR3 YJR140C Subunit of the HIR complex genetic 1 1 1 Negative Genetic
YJR142W YJR142W 8-oxo-dGTP diphosphatase of the Nudix hydrolase family genetic 1 1 1 Negative Genetic
HMS2 YJR147W Protein with similarity to heat shock transcription factors genetic 1 1 1 Negative Genetic
DAN4 YJR151C Cell wall mannoprotein genetic 1 1 1 Negative Genetic
PUT3 YKL015W Transcriptional activator genetic 1 1 1 Negative Genetic
HOT13 YKL084W Zinc-binding mitochondrial intermembrane space (IMS) protein genetic 1 1 1 Negative Genetic
RAD27 YKL113C 5' to 3' exonuclease, 5' flap endonuclease genetic 1 1 1 Negative Genetic
PMU1 YKL128C Putative phosphomutase genetic 1 1 1 Negative Genetic
CMC1 YKL137W Copper-binding protein of the mitochondrial intermembrane space genetic 1 1 1 Negative Genetic
PIR3 YKL163W O-glycosylated covalently-bound cell wall protein genetic 1 1 1 Negative Genetic
MRPL38 YKL170W Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
NAP1 YKR048C Histone chaperone and assembly chaperone for Rps6a/b genetic 1 1 1 Negative Genetic
DYN1 YKR054C Cytoplasmic heavy chain dynein genetic 1 1 1 Negative Genetic
TRM2 YKR056W tRNA methyltransferase genetic 1 1 1 Negative Genetic
TIF1 YKR059W Translation initiation factor eIF4A genetic 1 1 1 Negative Genetic
YKR070W YKR070W Putative protein of unknown function genetic 1 1 1 Negative Genetic
YLL006W-A YLL006W-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
COX17 YLL009C Copper metallochaperone that transfers copper to Sco1p and Cox11p genetic 1 1 1 Negative Genetic
RPL8B YLL045C Ribosomal 60S subunit protein L8A genetic 1 1 1 Negative Genetic
MEU1 YLR017W Methylthioadenosine phosphorylase (MTAP) genetic 1 1 1 Negative Genetic
PAU23 YLR037C Cell wall mannoprotein genetic 1 1 1 Negative Genetic
REX3 YLR107W RNA exonuclease genetic 1 1 1 Negative Genetic
SLX4 YLR135W Endonuclease involved in processing DNA genetic 1 1 1 Negative Genetic
RRT15 YLR162W-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
EST1 YLR233C TLC1 RNA-associated factor involved in telomere length regulation genetic 1 1 1 Negative Genetic
NDL1 YLR254C Homolog of nuclear distribution factor NudE genetic 1 1 1 Negative Genetic
HRI1 YLR301W Protein of unknown function that interacts with Sec72p and Hrr25p genetic 1 1 1 Negative Genetic
RPL38 YLR325C Ribosomal 60S subunit protein L38 genetic 1 1 1 Negative Genetic
TUS1 YLR425W Guanine nucleotide exchange factor (GEF) that modulates Rho1p activity genetic 1 1 1 Negative Genetic
PDP3 YLR455W Component of the NuA3b histone acetyltransferase complex genetic 1 1 1 Negative Genetic
GLO1 YML004C Monomeric glyoxalase I genetic 1 1 1 Negative Genetic
YAP1 YML007W Basic leucine zipper (bZIP) transcription factor genetic 1 1 1 Negative Genetic
TRM9 YML014W tRNA methyltransferase genetic 1 1 1 Negative Genetic
RAD52 YML032C Protein involved in homologous recombination genetic 1 1 1 Negative Genetic
YML082W YML082W Putative protein predicted to have carbon-sulfur lyase activity genetic 1 1 1 Negative Genetic
VPS9 YML097C Guanine nucleotide exchange factor (GEF) and ubiquitin receptor genetic 1 1 1 Negative Genetic
SPG4 YMR107W Protein required for high temperature survival during stationary phase genetic 1 1 1 Negative Genetic
INP2 YMR163C Peroxisome-specific receptor important for peroxisome inheritance genetic 1 1 1 Negative Genetic
YMR181C YMR181C Protein of unknown function genetic 1 1 1 Negative Genetic
GCV2 YMR189W P subunit of the mitochondrial glycine decarboxylase complex genetic 1 1 1 Negative Genetic
RPL36A YMR194W Ribosomal 60S subunit protein L36A genetic 1 1 1 Negative Genetic
RAD14 YMR201C Subunit of Nucleotide Excision Repair Factor 1 (NEF1) genetic 1 1 1 Negative Genetic
COG6 YNL041C Component of the conserved oligomeric Golgi complex genetic 1 1 1 Negative Genetic
SLM2 YNL047C Phosphoinositide PI4,5P(2) binding protein, forms a complex with Slm1p genetic 1 1 1 Negative Genetic
POR1 YNL055C Mitochondrial porin (voltage-dependent anion channel) genetic 1 1 1 Negative Genetic
NNR1 YNL200C NADHX epimerase genetic 1 1 1 Negative Genetic
MRX7 YNL211C Protein that associates with mitochondrial ribosome genetic 1 1 1 Negative Genetic
HCH1 YNL281W Heat shock protein regulator genetic 1 1 1 Negative Genetic
LEM3 YNL323W Membrane protein of the plasma membrane and ER genetic 1 1 1 Negative Genetic
VPS27 YNR006W Endosomal protein that forms a complex with Hse1p genetic 1 1 1 Negative Genetic
CSE2 YNR010W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
PHO91 YNR013C Low-affinity vacuolar phosphate transporter genetic 1 1 1 Negative Genetic
MAN2 YNR073C Mannitol dehydrogenase genetic 1 1 1 Negative Genetic
YNR075C-A YNR075C-A Protein of unknown function genetic 1 1 1 Negative Genetic
RPL33B YOR234C Ribosomal 60S subunit protein L33B genetic 1 1 1 Negative Genetic
SNF2 YOR290C Catalytic subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Negative Genetic
YOR293C-A YOR293C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
PDE2 YOR360C High-affinity cyclic AMP phosphodiesterase genetic 1 1 1 Negative Genetic
YOR365C YOR365C Putative protein involved in sphingolipid biosynthesis genetic 1 1 1 Negative Genetic
FRE5 YOR384W Putative ferric reductase with similarity to Fre2p genetic 1 1 1 Negative Genetic
YPL038W-A YPL038W-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
LGE1 YPL055C Protein involved in histone H2B ubiquitination genetic 1 1 1 Negative Genetic
SUR1 YPL057C Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit genetic 1 1 1 Negative Genetic
ERI1 YPL096C-A Endoplasmic reticulum membrane protein that binds and inhibits Ras2p genetic 1 1 1 Negative Genetic
MGR2 YPL098C Subunit of the TIM23 translocase complex genetic 1 1 1 Negative Genetic
RNY1 YPL123C Vacuolar RNase of the T(2) family genetic 1 1 1 Negative Genetic
KES1 YPL145C Sterol/phosphatidylinositol-4-phosphate (PI(4)P) exchanger genetic 1 1 1 Negative Genetic
YPR108W-A YPR108W-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
YPR172W YPR172W Protein of unknown function genetic 1 1 1 Negative Genetic
CSA1 YPR174C Protein of unknown function genetic 1 1 1 Negative Genetic
EMC4 YGL231C Member of conserved ER transmembrane complex genetic 1 1 1 Negative Genetic
POM34 YLR018C Subunit of the transmembrane ring of the nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
USO1 YDL058W Essential protein involved in vesicle-mediated ER to Golgi transport genetic 1 1 1 Negative Genetic
PRE7 YBL041W Beta 6 subunit of the 20S proteasome genetic 1 1 1 Positive Genetic
TRS85 YDR108W Component of transport protein particle (TRAPP) complex III genetic 1 1 1 Negative Genetic
OCA5 YHL029C Cytoplasmic protein required for replication of Brome mosaic virus genetic 1 1 1 Negative Genetic
GIM3 YNL153C Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Positive Genetic
MDY2 YOL111C Protein involved in inserting tail-anchored proteins into ER membranes genetic 1 1 1 Positive Genetic
PAC1 YOR269W Regulator of dynein, involved in intracellular transport genetic 1 1 1 Negative Genetic
SCD6 YPR129W Repressor of translation initiation genetic 1 1 1 Positive Genetic
KAP122 YGL016W Karyopherin beta genetic 1 1 1 Negative Genetic
SAE2 YGL175C Endonuclease required for telomere elongation genetic 1 1 1 Positive Genetic
OKP1 YGR179C Outer kinetochore protein required for accurate chromosome segregation genetic 1 1 1 Positive Genetic
GLE2 YER107C RNA export factor associated with the nuclear pore complex (NPC) genetic 1 1 1 Synthetic Growth Defect
SRS2 YJL092W DNA helicase and DNA-dependent ATPase genetic 1 1 1 Negative Genetic
SRN2 YLR119W Component of the ESCRT-I complex genetic 1 1 1 Negative Genetic
RIM20 YOR275C Protein involved in proteolytic activation of Rim101p genetic 1 1 1 Negative Genetic
KAP95 YLR347C Karyopherin beta genetic 1 1 1 Negative Genetic
THP2 YHR167W Subunit of the THO and TREX complexes genetic 1 1 1 Negative Genetic
VNX1 YNL321W Calcium/H+ antiporter localized to the endoplasmic reticulum membrane genetic 1 1 1 Negative Genetic
RTT10 YPL183C WD40 domain-containing protein involved in endosomal recycling genetic 1 1 1 Negative Genetic
NUP60 YAR002W FG-nucleoporin component of central core of the nuclear pore complex genetic 1 1 1 Negative Genetic
PML39 YML107C Protein required for nuclear retention of unspliced pre-mRNAs genetic 1 1 1 Negative Genetic
ERV29 YGR284C Protein localized to COPII-coated vesicles genetic 1 1 1 Negative Genetic
ERV25 YML012W Member of the p24 family involved in ER to Golgi transport genetic 1 1 1 Negative Genetic
ERG3 YLR056W C-5 sterol desaturase genetic 1 1 1 Negative Genetic
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 1 1 1 Negative Genetic
BUR6 YER159C Subunit of a heterodimeric NC2 transcription regulator complex genetic 1 1 1 Negative Genetic
CCP1 YKR066C Mitochondrial cytochrome-c peroxidase genetic 1 1 1 Negative Genetic
BUD2 YKL092C GTPase activating factor for Rsr1p/Bud1p genetic 1 1 1 Negative Genetic
CDC19 YAL038W Pyruvate kinase genetic 1 1 1 Negative Genetic
ATG10 YLL042C Conserved E2-like conjugating enzyme genetic 1 1 1 Negative Genetic
BET4 YJL031C Alpha subunit of Type II geranylgeranyltransferase genetic 1 1 1 Negative Genetic
ATM1 YMR301C Mitochondrial inner membrane ATP-binding cassette (ABC) transporter genetic 1 1 1 Negative Genetic
AHK1 YDL073W Scaffold protein in the HKR1 sub-branch of the Hog1p-signaling pathway genetic 1 1 1 Negative Genetic
CAB4 YGR277C Subunit of the CoA-Synthesizing Protein Complex (CoA-SPC) genetic 1 1 1 Negative Genetic
ATP12 YJL180C Assembly factor for F1 sector of mitochondrial F1F0 ATP synthase genetic 1 1 1 Negative Genetic
ANB1 YJR047C Translation elongation factor eIF-5A genetic 1 1 1 Negative Genetic
AIM23 YJL131C Mitochondrial translation initiation factor 3 (IF3, mIF3) genetic 1 1 1 Negative Genetic
APD1 YBR151W 2Fe-2S cytosolic protein of unknown function genetic 1 1 1 Negative Genetic
AIM29 YKR074W Protein of unknown function genetic 1 1 1 Negative Genetic
ARO10 YDR380W Phenylpyruvate decarboxylase genetic 1 1 1 Negative Genetic
ASP3-4 YLR160C Cell-wall L-asparaginase II involved in asparagine catabolism genetic 1 1 1 Negative Genetic
ASP3-2 YLR157C Cell-wall L-asparaginase II involved in asparagine catabolism genetic 1 1 1 Negative Genetic
APA2 YDR530C Diadenosine 5',5'''-P1,P4-tetraphosphate phosphorylase II genetic 1 1 1 Negative Genetic
CBP4 YGR174C Mitochondrial protein required for assembly of cytochrome bc1 complex genetic 1 1 1 Negative Genetic
CDC1 YDR182W Putative mannose-ethanolamine phosphate phosphodiesterase genetic 1 1 1 Negative Genetic
AIM10 YER087W Protein with similarity to tRNA synthetases genetic 1 1 1 Negative Genetic
AGP3 YFL055W Low-affinity amino acid permease genetic 1 1 1 Negative Genetic