PHO84 |
YML123C |
High-affinity inorganic phosphate (Pi) transporter |
genetic |
6 |
4 |
5 |
Synthetic Lethality, Phenotypic Enhancement, Phenotypic Suppression, Synthetic Lethality, Synthetic Growth Defect, Synthetic Growth Defect |
RIM101 |
YHL027W |
Cys2His2 zinc-finger transcriptional repressor |
regulation |
4 |
4 |
2 |
beta-galactosidase reporter gene assay evidence, DNA to cDNA expression microarray evidence, qualitative western immunoblotting evidence, reverse transcription polymerase chain reaction evidence |
PHO4 |
YFR034C |
Basic helix-loop-helix (bHLH) transcription factor of the myc-family |
regulation |
4 |
4 |
2 |
beta-galactosidase reporter gene assay evidence, chromatin immunoprecipitation-chip evidence, qualitative western immunoblotting evidence, reverse transcription polymerase chain reaction evidence |
CRZ1 |
YNL027W |
Transcription factor, activates transcription of stress response genes |
regulation |
4 |
4 |
2 |
beta-galactosidase reporter gene assay evidence, chromatin immunoprecipitation-PCR evidence, chromatin immunoprecipitation-seq evidence, DNA to cDNA expression microarray evidence |
RAP1 |
YNL216W |
Essential DNA-binding transcription regulator that binds many loci |
regulation |
2 |
2 |
2 |
chromatin immunoprecipitation-chip evidence, DNA to cDNA expression microarray evidence |
PHO87 |
YCR037C |
Low-affinity inorganic phosphate (Pi) transporter |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
PHO90 |
YJL198W |
Low-affinity phosphate transporter |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
SPT10 |
YJL127C |
Histone H3 acetylase with a role in transcriptional regulation |
regulation |
2 |
1 |
2 |
DNA to cDNA expression microarray evidence, DNA to cDNA expression microarray evidence |
MFA2 |
YNL145W |
Mating pheromone a-factor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SFP1 |
YLR403W |
Regulates transcription of ribosomal protein and biogenesis genes |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
AFT2 |
YPL202C |
Iron-regulated transcriptional activator |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
GCR1 |
YPL075W |
Transcriptional activator of genes involved in glycolysis |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
GCR2 |
YNL199C |
Transcriptional activator of genes involved in glycolysis |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
HFI1 |
YPL254W |
Adaptor protein required for structural integrity of the SAGA complex |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
MET32 |
YDR253C |
Zinc-finger DNA-binding transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
MET4 |
YNL103W |
Leucine-zipper transcriptional activator |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RPN4 |
YDL020C |
Transcription factor that stimulates expression of proteasome genes |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
SPT20 |
YOL148C |
Subunit of the SAGA transcriptional regulatory complex |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
STB5 |
YHR178W |
Transcription factor |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
YAP6 |
YDR259C |
Basic leucine zipper (bZIP) transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
HSF1 |
YGL073W |
Trimeric heat shock transcription factor |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
MIG1 |
YGL035C |
Transcription factor involved in glucose repression |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
MIG2 |
YGL209W |
Zinc finger transcriptional repressor |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
ZAP1 |
YJL056C |
Zinc-regulated transcription factor |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
SPT3 |
YDR392W |
Subunit of the SAGA and SAGA-like transcriptional regulatory complexes |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
YAP5 |
YIR018W |
Basic leucine zipper (bZIP) iron-sensing transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
CIN5 |
YOR028C |
Basic leucine zipper (bZIP) transcription factor of the yAP-1 family |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
GCN4 |
YEL009C |
bZIP transcriptional activator of amino acid biosynthetic genes |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
SPT2 |
YER161C |
Protein involved in negative regulation of transcription |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
SIN3 |
YOL004W |
Component of both the Rpd3S and Rpd3L histone deacetylase complexes |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
MAC1 |
YMR021C |
Copper-sensing transcription factor |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
PHO2 |
YDL106C |
Homeobox transcription factor |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
SOK2 |
YMR016C |
Nuclear protein that negatively regulates pseudohyphal differentiation |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
AZF1 |
YOR113W |
Zinc-finger transcription factor |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
MSS11 |
YMR164C |
Transcription factor |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
CUP9 |
YPL177C |
Homeodomain-containing transcriptional repressor |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
ARO80 |
YDR421W |
Zinc finger transcriptional activator of the Zn2Cys6 family |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
CAT8 |
YMR280C |
Zinc cluster transcriptional activator |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
RDS2 |
YPL133C |
Transcription factor involved in regulating gluconeogenesis |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
PGD1 |
YGL025C |
Subunit of the RNA polymerase II mediator complex |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
RME1 |
YGR044C |
Zinc finger protein involved in control of meiosis |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
PDR8 |
YLR266C |
Transcription factor |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
NSE3 |
YDR288W |
Component of the SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARP4 |
YJL081C |
Nuclear actin-related protein involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARC1 |
YGL105W |
Protein that binds tRNA and methionyl- and glutamyl-tRNA synthetases |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NPL3 |
YDR432W |
RNA-binding protein |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
CDC12 |
YHR107C |
Component of the septin ring that is required for cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
DCP2 |
YNL118C |
Catalytic subunit of Dcp1p-Dcp2p decapping enzyme complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
NAB3 |
YPL190C |
RNA-binding protein, subunit of Nrd1 complex (Nrd1p-Nab3p-Sen1p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC25 |
YLR310C |
Membrane bound guanine nucleotide exchange factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC53 |
YDL132W |
Cullin |
genetic |
1 |
1 |
1 |
Negative Genetic |
MET30 |
YIL046W |
F-box protein containing five copies of the WD40 motif |
genetic |
1 |
1 |
1 |
Negative Genetic |
HHO1 |
YPL127C |
Histone H1, linker histone with roles in meiosis and sporulation |
genetic |
1 |
1 |
1 |
Negative Genetic |
KIN28 |
YDL108W |
Ser/Thr protein kinase and subunit of TFIIK, a TFIIH subassembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
EXO70 |
YJL085W |
Subunit of the exocyst complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
MCM10 |
YIL150C |
Essential chromatin-associated protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
CWC24 |
YLR323C |
General splicing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
HSP10 |
YOR020C |
Mitochondrial matrix co-chaperonin |
genetic |
1 |
1 |
1 |
Negative Genetic |
APC11 |
YDL008W |
Catalytic core subunit, Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC21 |
YOR074C |
Thymidylate synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
AMD1 |
YML035C |
AMP deaminase |
genetic |
1 |
1 |
1 |
Negative Genetic |
IES2 |
YNL215W |
Protein that associates with the INO80 chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
GSY2 |
YLR258W |
Glycogen synthase |
genetic |
1 |
1 |
1 |
Positive Genetic |
ATP15 |
YPL271W |
Epsilon subunit of the F1 sector of mitochondrial F1F0 ATP synthase |
genetic |
1 |
1 |
1 |
Positive Genetic |
IRC7 |
YFR055W |
Cysteine desulphydrase, enables growth on cysteine as nitrogen source |
genetic |
1 |
1 |
1 |
Negative Genetic |
NSG1 |
YHR133C |
Protein involved in regulation of sterol biosynthesis |
physical |
1 |
1 |
1 |
PCA |
MET7 |
YOR241W |
Folylpolyglutamate synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MDM32 |
YOR147W |
Mitochondrial inner membrane protein with similarity to Mdm31p |
genetic |
1 |
1 |
1 |
Negative Genetic |
DAL2 |
YIR029W |
Allantoicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC8 |
YJR057W |
Nucleoside monophosphate and nucleoside diphosphate kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
GRX6 |
YDL010W |
Cis-Golgi localized monothiol glutaredoxin, binds Fe-S cluster |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
TPO1 |
YLL028W |
Polyamine transporter of the major facilitator superfamily |
physical |
1 |
1 |
1 |
PCA |
RPL3 |
YOR063W |
Ribosomal 60S subunit protein L3 |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
PHO89 |
YBR296C |
Plasma membrane Na+/Pi cotransporter |
physical |
1 |
1 |
1 |
Co-purification |
PMT6 |
YGR199W |
Protein O-mannosyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RSC4 |
YKR008W |
Component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PHO91 |
YNR013C |
Low-affinity vacuolar phosphate transporter |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
SKI7 |
YOR076C |
GTP-binding protein that couples the Ski complex and exosome |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
SUP35 |
YDR172W |
Translation termination factor eRF3 |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
YPT53 |
YNL093W |
Stress-induced Rab family GTPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
TPS3 |
YMR261C |
Regulatory subunit of trehalose-6-phosphate synthase/phosphatase |
genetic |
1 |
1 |
1 |
Positive Genetic |
TEL2 |
YGR099W |
Subunit of the ASTRA complex, involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Positive Genetic |
STU1 |
YBL034C |
Microtubule plus-end-tracking non-motor protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPS8A |
YBL072C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPN1 |
YHR027C |
Non-ATPase base subunit of the 19S RP of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPO21 |
YDL140C |
RNA polymerase II largest subunit B220 |
genetic |
1 |
1 |
1 |
Negative Genetic |
SYF1 |
YDR416W |
Member of the NineTeen Complex (NTC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
RSP5 |
YER125W |
NEDD4 family E3 ubiquitin ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRP18 |
YGR006W |
Splicing factor and component of snRNP U5 |
genetic |
1 |
1 |
1 |
Negative Genetic |
SMD1 |
YGR074W |
Core Sm protein Sm D1 |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPT1 |
YKL145W |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
TAD3 |
YLR316C |
Subunit of tRNA-specific adenosine-34 deaminase |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS52 |
YDR484W |
Component of the GARP (Golgi-associated retrograde protein) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ZRT3 |
YKL175W |
Vacuolar membrane zinc transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |