Standard name Systematic name Name description Description
GSY2 YLR258W Glycogen synthase Glycogen synthase; expression induced by glucose limitation, nitrogen starvation, heat shock, and stationary phase; activity regulated by cAMP-dependent, Snf1p and Pho85p kinases as well as by the Gac1p-Glc7p phosphatase; GSY2 has a paralog, GSY1, that arose from the whole genome duplication; relocalizes from cytoplasm to plasma membrane upon DNA replication stress
Visualize the interactome of GSY2
Links to external databases:
SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)
M 163

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.985 0.938 0.973

GFP localization & abundance

GFP localization GFP abundance
cytoplasm, nucleus, punctate composite 14600

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
GSY2 1 0 0 0 0

Enzyme information

Catalyzed reactions in Yeast8
r_0510 (glycogen (starch) synthase)

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
PHO85 YPL031C Cyclin-dependent kinase physical 6 4 5 Biochemical Activity, Biochemical Activity, Two-hybrid, Biochemical Activity, Affinity Capture-MS, Reconstituted Complex
GLG2 YJL137C Glycogenin glucosyltransferase physical 6 3 5 Two-hybrid, Two-hybrid, Two-hybrid, Affinity Capture-MS, Two-hybrid, Reconstituted Complex
GSY2 YLR258W Glycogen synthase physical 4 3 4 Two-hybrid, PCA, PCA, Co-crystal Structure
PCL10 YGL134W Pho85p cyclin physical 4 4 3 Two-hybrid, Affinity Capture-Western, Affinity Capture-MS, Reconstituted Complex
GSY1 YFR015C Glycogen synthase physical 3 3 3 Affinity Capture-MS, Two-hybrid, Affinity Capture-Western
FKH1 YIL131C Forkhead family transcription factor regulation 3 2 3 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments
GLC7 YER133W Type 1 S/T protein phosphatase (PP1) catalytic subunit physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 3 1 3 Affinity Capture-RNA, Affinity Capture-RNA, Affinity Capture-RNA
GSY1 YFR015C Glycogen synthase genetic 3 2 2 Synthetic Growth Defect, Synthetic Lethality, Synthetic Lethality
FKH2 YNL068C Forkhead family transcription factor regulation 2 2 2 chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments
PIG2 YIL045W Putative type-1 protein phosphatase targeting subunit physical 2 2 2 Two-hybrid, Affinity Capture-MS
MEK1 YOR351C Meiosis-specific serine/threonine protein kinase physical 2 2 2 Biochemical Activity, Reconstituted Complex
HRR25 YPL204W Conserved casein kinase, monopolin subunit physical 2 2 2 Affinity Capture-MS, Reconstituted Complex
GLG1 YKR058W Glycogenin glucosyltransferase physical 2 2 2 Affinity Capture-MS, PCA
MSN2 YMR037C Stress-responsive transcriptional activator regulation 2 1 2 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence
YPL245W YPL245W Putative protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
TPS1 YBR126C Synthase subunit of trehalose-6-P synthase/phosphatase complex genetic 2 1 2 Phenotypic Enhancement, Phenotypic Enhancement
ATP10 YLR393W Assembly factor for the F0 sector of mitochondrial F1F0 ATP synthase genetic 2 1 2 Negative Genetic, Negative Genetic
IXR1 YKL032C Transcriptional repressor that regulates hypoxic genes during normoxia regulation 1 1 1 DNA to cDNA expression microarray evidence
MED2 YDL005C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
XBP1 YIL101C Transcriptional repressor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
BUR6 YER159C Subunit of a heterodimeric NC2 transcription regulator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAP1 YML007W Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit regulation 1 1 1 quantitative mass spectrometry evidence
CYC8 YBR112C General transcriptional co-repressor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MED4 YOR174W Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SUA7 YPR086W Transcription factor TFIIB regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SPT3 YDR392W Subunit of the SAGA and SAGA-like transcriptional regulatory complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SKN7 YHR206W Nuclear response regulator and transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
TUP1 YCR084C General repressor of transcription in complex with Cyc8p regulation 1 1 1 chromatin immunoprecipitation-chip evidence
NHP6A YPR052C High-mobility group (HMG) protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
GLC7 YER133W Type 1 S/T protein phosphatase (PP1) catalytic subunit genetic 1 1 1 Synthetic Rescue
ESA1 YOR244W Catalytic subunit of the histone acetyltransferase complex (NuA4) physical 1 1 1 Biochemical Activity
EAF1 YDR359C Component of the NuA4 histone acetyltransferase complex genetic 1 1 1 Dosage Growth Defect
BMH1 YER177W 14-3-3 protein, major isoform physical 1 1 1 Affinity Capture-MS
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit physical 1 1 1 PCA
GCD7 YLR291C Beta subunit of translation initiation factor eIF2B physical 1 1 1 Two-hybrid
CMR1 YDL156W Nuclear protein with role in transcription, protein quality control physical 1 1 1 Affinity Capture-MS
CMD1 YBR109C Calmodulin genetic 1 1 1 Negative Genetic
GIN4 YDR507C Protein kinase involved in bud growth and assembly of the septin ring physical 1 1 1 Reconstituted Complex
ADE57 YGL234W Bifunctional enzyme of 'de novo' purine nucleotide pathway physical 1 1 1 Affinity Capture-MS
ANP1 YEL036C Subunit of the alpha-1,6 mannosyltransferase complex genetic 1 1 1 Negative Genetic
BBC1 YJL020C Protein possibly involved in assembly of actin patches physical 1 1 1 Affinity Capture-MS
AKL1 YBR059C Ser/Thr protein kinase physical 1 1 1 Reconstituted Complex
GND1 YHR183W 6-phosphogluconate dehydrogenase (decarboxylating) genetic 1 1 1 Negative Genetic
CHK1 YBR274W Serine/threonine kinase and DNA damage checkpoint effector physical 1 1 1 Two-hybrid
GIP2 YER054C Putative regulatory subunit of protein phosphatase Glc7p physical 1 1 1 Affinity Capture-MS
GDB1 YPR184W Glycogen debranching enzyme physical 1 1 1 PCA
GAC1 YOR178C Regulatory subunit for Glc7p type-1 protein phosphatase (PP1) physical 1 1 1 Affinity Capture-Western
CDC15 YAR019C Hippo-like kinase of the Mitotic Exit Network physical 1 1 1 Reconstituted Complex
ADE17 YMR120C Enzyme of 'de novo' purine biosynthesis physical 1 1 1 PCA
DEF1 YKL054C RNAPII degradation factor physical 1 1 1 Affinity Capture-MS
BUB3 YOR026W Kinetochore checkpoint WD40 repeat protein physical 1 1 1 Affinity Capture-MS
FMP48 YGR052W Putative protein of unknown function physical 1 1 1 Affinity Capture-MS
CLN3 YAL040C G1 cyclin involved in cell cycle progression genetic 1 1 1 Phenotypic Suppression
ENT3 YJR125C Protein containing an N-terminal epsin-like domain physical 1 1 1 Reconstituted Complex
PIG1 YLR273C Putative targeting subunit for type-1 protein phosphatase Glc7p physical 1 1 1 Two-hybrid
PHO85 YPL031C Cyclin-dependent kinase genetic 1 1 1 Dosage Lethality
MES1 YGR264C Methionyl-tRNA synthetase physical 1 1 1 Affinity Capture-MS
PSE1 YMR308C Karyopherin/importin that interacts with the nuclear pore complex physical 1 1 1 Affinity Capture-MS
MSH2 YOL090W Protein that binds to DNA mismatches physical 1 1 1 Affinity Capture-MS
RTT102 YGR275W Component of both the SWI/SNF and RSC chromatin remodeling complexes physical 1 1 1 Affinity Capture-MS
MCK1 YNL307C Dual-specificity ser/thr and tyrosine protein kinase physical 1 1 1 Biochemical Activity
PTK2 YJR059W Serine/threonine protein kinase physical 1 1 1 Biochemical Activity
RIM11 YMR139W Protein kinase physical 1 1 1 Biochemical Activity
TPK1 YJL164C cAMP-dependent protein kinase catalytic subunit physical 1 1 1 Biochemical Activity
PKP2 YGL059W Mitochondrial protein kinase physical 1 1 1 Biochemical Activity
RRD1 YIL153W Peptidyl-prolyl cis/trans-isomerase physical 1 1 1 Two-hybrid
PCL8 YPL219W Cyclin physical 1 1 1 Affinity Capture-MS
PSK1 YAL017W PAS domain-containing serine/threonine protein kinase physical 1 1 1 Affinity Capture-MS
KSP1 YHR082C Serine/threonine protein kinase physical 1 1 1 Reconstituted Complex
PKH2 YOL100W Serine/threonine protein kinase physical 1 1 1 Reconstituted Complex
YGK3 YOL128C Protein kinase related to mammalian GSK-3 glycogen synthase kinases physical 1 1 1 Reconstituted Complex
RSP5 YER125W NEDD4 family E3 ubiquitin ligase physical 1 1 1 Protein-peptide
SBP1 YHL034C Protein that binds eIF4G and has a role in repression of translation physical 1 1 1 Affinity Capture-RNA
NAM7 YMR080C ATP-dependent RNA helicase of the SFI superfamily physical 1 1 1 Affinity Capture-RNA
PUF3 YLL013C Protein of the mitochondrial outer surface physical 1 1 1 Affinity Capture-RNA
SPT10 YJL127C Histone H3 acetylase with a role in transcriptional regulation physical 1 1 1 Affinity Capture-MS
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
NUP100 YKL068W FG-nucleoporin component of central core of the nuclear pore complex physical 1 1 1 Affinity Capture-MS
TFC6 YDR362C Subunit of RNA polymerase III transcription initiation factor complex physical 1 1 1 Affinity Capture-MS
RRP43 YCR035C Exosome non-catalytic core component physical 1 1 1 Affinity Capture-MS
SNF1 YDR477W AMP-activated S/T protein kinase genetic 1 1 1 Phenotypic Suppression
RTT109 YLL002W Histone acetyltransferase genetic 1 1 1 Synthetic Growth Defect
REG1 YDR028C Regulatory subunit of type 1 protein phosphatase Glc7p genetic 1 1 1 Phenotypic Suppression
INP53 YOR109W Polyphosphatidylinositol phosphatase genetic 1 1 1 Negative Genetic
SGA1 YIL099W Intracellular sporulation-specific glucoamylase genetic 1 1 1 Negative Genetic
MPH3 YJR160C Alpha-glucoside permease genetic 1 1 1 Positive Genetic
TPS2 YDR074W Phosphatase subunit of the trehalose-6-P synthase/phosphatase complex genetic 1 1 1 Positive Genetic
PHO87 YCR037C Low-affinity inorganic phosphate (Pi) transporter genetic 1 1 1 Positive Genetic
PHO89 YBR296C Plasma membrane Na+/Pi cotransporter genetic 1 1 1 Positive Genetic
MMM1 YLL006W ER integral membrane protein, ERMES complex subunit genetic 1 1 1 Negative Genetic
PPA2 YMR267W Mitochondrial inorganic pyrophosphatase genetic 1 1 1 Negative Genetic
HER2 YMR293C Subunit of the trimeric GatFAB AmidoTransferase(AdT) complex genetic 1 1 1 Negative Genetic
NPL3 YDR432W RNA-binding protein genetic 1 1 1 Synthetic Rescue
HOG1 YLR113W Mitogen-activated protein kinase involved in osmoregulation genetic 1 1 1 Dosage Growth Defect
PAC11 YDR488C Dynein intermediate chain, microtubule motor protein genetic 1 1 1 Positive Genetic
POL30 YBR088C Proliferating cell nuclear antigen (PCNA) genetic 1 1 1 Negative Genetic
MOB2 YFL034C-B Activator of Cbk1p kinase genetic 1 1 1 Negative Genetic
PRP24 YMR268C Splicing factor that reanneals snRNPs during spliceosome recycling genetic 1 1 1 Negative Genetic
YDR391C YDR391C Putative protein of unknown function genetic 1 1 1 Negative Genetic
PHO4 YFR034C Basic helix-loop-helix (bHLH) transcription factor of the myc-family genetic 1 1 1 Negative Genetic
PHB2 YGR231C Subunit of the prohibitin complex (Phb1p-Phb2p) genetic 1 1 1 Negative Genetic
MRS1 YIR021W Splicing protein genetic 1 1 1 Negative Genetic
YNK1 YKL067W Nucleoside diphosphate kinase genetic 1 1 1 Negative Genetic
RIM15 YFL033C Protein kinase involved in cell proliferation in response to nutrients genetic 1 1 1 Phenotypic Suppression
YAK1 YJL141C Serine-threonine protein kinase genetic 1 1 1 Phenotypic Suppression
MME1 YMR166C Transporter of the mitochondrial inner membrane that exports magnesium genetic 1 1 1 Negative Genetic
THI20 YOL055C Trifunctional enzyme of thiamine biosynthesis, degradation and salvage genetic 1 1 1 Negative Genetic
VPS30 YPL120W Subunit of phosphatidylinositol (PtdIns) 3-kinase complexes I and II genetic 1 1 1 Negative Genetic
CMR2 YOR093C Putative protein of unknown function genetic 1 1 1 Negative Genetic
FRK1 YPL141C Protein kinase of unknown cellular role physical 1 1 1 Reconstituted Complex
FRK1 YPL141C Protein kinase of unknown cellular role genetic 1 1 1 Dosage Growth Defect
FMP23 YBR047W Putative protein of unknown function genetic 1 1 1 Negative Genetic
GEP5 YLR091W Protein of unknown function genetic 1 1 1 Negative Genetic
CHS7 YHR142W Protein of unknown function genetic 1 1 1 Negative Genetic
EOS1 YNL080C Protein involved in N-glycosylation genetic 1 1 1 Negative Genetic
EEB1 YPL095C Acyl-coenzymeA:ethanol O-acyltransferase genetic 1 1 1 Negative Genetic
AAD15 YOL165C Putative aryl-alcohol dehydrogenase genetic 1 1 1 Negative Genetic
ECM4 YKR076W S-glutathionyl-(chloro)hydroquinone reductase (GS-HQR) genetic 1 1 1 Negative Genetic
BUD25 YER014C-A Protein involved in bud-site selection genetic 1 1 1 Negative Genetic