Standard name Systematic name Name description Description
PKP2 YGL059W Mitochondrial protein kinase Mitochondrial protein kinase; negatively regulates activity of the pyruvate dehydrogenase complex by phosphorylating the ser-133 residue of the Pda1p subunit; acts in concert with kinase Pkp1p and phosphatases Ptc5p and Ptc6p; relocalizes from mitochondrion to cytoplasm upon DNA replication stress
Visualize the interactome of PKP2
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Mito 0.861 NaN 0.752
Nucleolus 0.057 NaN NaN
Peroxisome 0.057 NaN 0.214
SpindlePole 0.076 NaN 0.092
Vac/Vac Memb 0.051 NaN 0.082
Bud NaN NaN 0.051
Endosome NaN NaN 0.160

GFP localization & abundance

GFP localization GFP abundance
no data no data

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
PKP2 2 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
ELM1 YKL048C Serine/threonine protein kinase genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
PKP1 YIL042C Mitochondrial protein kinase physical 3 2 2 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western
PKP1 YIL042C Mitochondrial protein kinase genetic 2 2 2 Synthetic Growth Defect, Phenotypic Enhancement
BUB3 YOR026W Kinetochore checkpoint WD40 repeat protein genetic 2 1 2 Negative Genetic, Negative Genetic
GGA1 YDR358W Golgi-localized protein with homology to gamma-adaptin genetic 2 1 2 Positive Genetic, Positive Genetic
EUG1 YDR518W Protein disulfide isomerase of the endoplasmic reticulum lumen genetic 2 1 2 Negative Genetic, Negative Genetic
RHO2 YNL090W Non-essential small GTPase of the Rho/Rac family of Ras-like proteins genetic 2 1 2 Negative Genetic, Negative Genetic
SGT1 YOR057W Cochaperone protein genetic 2 1 2 Positive Genetic, Positive Genetic
GLC7 YER133W Type 1 S/T protein phosphatase (PP1) catalytic subunit genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
IXR1 YKL032C Transcriptional repressor that regulates hypoxic genes during normoxia regulation 1 1 1 DNA to cDNA expression microarray evidence
MED2 YDL005C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SUA7 YPR086W Transcription factor TFIIB regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAP5 YIR018W Basic leucine zipper (bZIP) iron-sensing transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
GCN4 YEL009C bZIP transcriptional activator of amino acid biosynthetic genes regulation 1 1 1 DNA to cDNA expression microarray evidence
CWC25 YNL245C Splicing factor required for the first step of pre-mRNA splicing physical 1 1 1 Biochemical Activity
MMS21 YEL019C Highly conserved SUMO E3 ligase subunit of SMC5-SMC6 complex genetic 1 1 1 Positive Genetic
HSP60 YLR259C Tetradecameric mitochondrial chaperonin genetic 1 1 1 Negative Genetic
ARC1 YGL105W Protein that binds tRNA and methionyl- and glutamyl-tRNA synthetases physical 1 1 1 Biochemical Activity
NAP1 YKR048C Histone chaperone and assembly chaperone for Rps6a/b physical 1 1 1 Biochemical Activity
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
BMH2 YDR099W 14-3-3 protein, minor isoform physical 1 1 1 Biochemical Activity
CTK1 YKL139W Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) genetic 1 1 1 Positive Genetic
EXO84 YBR102C Exocyst subunit with dual roles in exocytosis and spliceosome assembly genetic 1 1 1 Negative Genetic
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
MAK5 YBR142W Essential nucleolar protein physical 1 1 1 Biochemical Activity
MRPL10 YNL284C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
MAM33 YIL070C Acidic protein of the mitochondrial matrix physical 1 1 1 Biochemical Activity
NPL4 YBR170C Substrate-recruiting cofactor of the Cdc48p-Npl4p-Ufd1p segregase physical 1 1 1 Biochemical Activity
HSP82 YPL240C Hsp90 chaperone physical 1 1 1 Biochemical Activity
NUT2 YPR168W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
OSH2 YDL019C Member of an oxysterol-binding protein family with seven members physical 1 1 1 Biochemical Activity
CMS1 YLR003C Putative subunit of the 90S preribosome processome complex physical 1 1 1 Biochemical Activity
AKL1 YBR059C Ser/Thr protein kinase physical 1 1 1 Biochemical Activity
CAF20 YOR276W Phosphoprotein of the mRNA cap-binding complex physical 1 1 1 Affinity Capture-RNA
FOL2 YGR267C GTP-cyclohydrolase I, catalyzes first step in folic acid biosynthesis physical 1 1 1 Biochemical Activity
DPS1 YLL018C Aspartyl-tRNA synthetase, primarily cytoplasmic physical 1 1 1 Biochemical Activity
GSF2 YML048W Endoplasmic reticulum (ER) localized integral membrane protein physical 1 1 1 Biochemical Activity
EST1 YLR233C TLC1 RNA-associated factor involved in telomere length regulation genetic 1 1 1 Synthetic Growth Defect
KSP1 YHR082C Serine/threonine protein kinase physical 1 1 1 Biochemical Activity
KSP1 YHR082C Serine/threonine protein kinase genetic 1 1 1 Negative Genetic
ADE17 YMR120C Enzyme of 'de novo' purine biosynthesis physical 1 1 1 Biochemical Activity
ICP55 YER078C Mitochondrial aminopeptidase physical 1 1 1 Biochemical Activity
NOP53 YPL146C Nucleolar protein genetic 1 1 1 Positive Genetic
DUT1 YBR252W Deoxyuridine triphosphate diphosphatase (dUTPase) genetic 1 1 1 Positive Genetic
DHR2 YKL078W Predominantly nucleolar DEAH-box ATP-dependent RNA helicase genetic 1 1 1 Positive Genetic
ESS1 YJR017C Peptidylprolyl-cis/trans-isomerase (PPIase) genetic 1 1 1 Synthetic Growth Defect
CTK3 YML112W Gamma subunit of C-terminal domain kinase I genetic 1 1 1 Positive Genetic
LAC1 YKL008C Ceramide synthase component physical 1 1 1 Biochemical Activity
ATG1 YGL180W Protein serine/threonine kinase physical 1 1 1 Biochemical Activity
COG2 YGR120C Essential component of the conserved oligomeric Golgi complex genetic 1 1 1 Negative Genetic
ALY2 YJL084C Alpha arrestin, Ub-ligase adaptor for Rsp5p physical 1 1 1 Biochemical Activity
PFS1 YHR185C Sporulation protein required for prospore membrane formation physical 1 1 1 Biochemical Activity
NBA1 YOL070C Protein involved in axial bud site selection physical 1 1 1 Biochemical Activity
LDB17 YDL146W Protein involved in the regulation of endocytosis genetic 1 1 1 Negative Genetic
AIM7 YDR063W Protein that interacts with Arp2/3 complex genetic 1 1 1 Negative Genetic
FMP16 YDR070C Protein of unknown function physical 1 1 1 Biochemical Activity
EXO1 YOR033C 5'-3' exonuclease and flap-endonuclease genetic 1 1 1 Negative Genetic
BAG7 YOR134W Rho GTPase activating protein (RhoGAP) physical 1 1 1 Biochemical Activity
BUD6 YLR319C Actin- and formin-interacting protein physical 1 1 1 Biochemical Activity
GSY2 YLR258W Glycogen synthase physical 1 1 1 Biochemical Activity
NNK1 YKL171W Protein kinase physical 1 1 1 Biochemical Activity
MGA1 YGR249W Protein similar to heat shock transcription factor physical 1 1 1 Biochemical Activity
AZF1 YOR113W Zinc-finger transcription factor physical 1 1 1 Biochemical Activity
HBT1 YDL223C Shmoo tip protein, substrate of Hub1p ubiquitin-like protein physical 1 1 1 Biochemical Activity
MLS1 YNL117W Malate synthase, enzyme of the glyoxylate cycle physical 1 1 1 Biochemical Activity
OKP1 YGR179C Outer kinetochore protein required for accurate chromosome segregation physical 1 1 1 Biochemical Activity
FRA1 YLL029W Protein involved in negative regulation of iron regulon transcription physical 1 1 1 Biochemical Activity
ALG1 YBR110W Mannosyltransferase genetic 1 1 1 Negative Genetic
PAH1 YMR165C Mg2+-dependent phosphatidate (PA) phosphatase physical 1 1 1 Biochemical Activity
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 1 1 1 Positive Genetic
KCS1 YDR017C Inositol hexakisphosphate and inositol heptakisphosphate kinase genetic 1 1 1 Negative Genetic
AVT1 YJR001W Vacuolar transporter physical 1 1 1 Biochemical Activity
MBR1 YKL093W Protein involved in mitochondrial functions and stress response physical 1 1 1 Biochemical Activity
PFK26 YIL107C 6-phosphofructo-2-kinase physical 1 1 1 Biochemical Activity
DOS2 YDR068W Protein of unknown function physical 1 1 1 Biochemical Activity
IGD1 YFR017C Cytoplasmic protein that inhibits Gdb1p glycogen debranching activity physical 1 1 1 Biochemical Activity
ALR2 YFL050C Probable Mg(2+) transporter physical 1 1 1 Biochemical Activity
CMK2 YOL016C Calmodulin-dependent protein kinase physical 1 1 1 Biochemical Activity
MSN4 YKL062W Stress-responsive transcriptional activator physical 1 1 1 Biochemical Activity
ENT4 YLL038C Protein of unknown function physical 1 1 1 Biochemical Activity
ICS2 YBR157C Protein of unknown function physical 1 1 1 Biochemical Activity
ORM1 YGR038W Protein that mediates sphingolipid homeostasis physical 1 1 1 Biochemical Activity
NMT1 YLR195C N-myristoyl transferase physical 1 1 1 Biochemical Activity
MNR2 YKL064W Vacuolar membrane protein required for magnesium homeostasis physical 1 1 1 Biochemical Activity
MLF3 YNL074C Serine-rich protein of unknown function physical 1 1 1 Biochemical Activity
DAP2 YHR028C Dipeptidyl aminopeptidase physical 1 1 1 Biochemical Activity
LCL1 YPL056C Putative protein of unknown function physical 1 1 1 Biochemical Activity
ALG6 YOR002W ER-luminal alpha 1,3 glucosyltransferase physical 1 1 1 Biochemical Activity
SCM3 YDL139C Nonhistone component of centromeric chromatin physical 1 1 1 Biochemical Activity
PRS1 YKL181W 5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase physical 1 1 1 Biochemical Activity
TOM71 YHR117W Mitochondrial outer membrane protein physical 1 1 1 Biochemical Activity
STF2 YGR008C Protein involved in resistance to desiccation stress physical 1 1 1 Biochemical Activity
RPS1B YML063W Ribosomal protein of the small (40S) subunit physical 1 1 1 Biochemical Activity
YPL077C YPL077C Putative protein of unknown function physical 1 1 1 Biochemical Activity
REC104 YHR157W Protein involved in early stages of meiotic recombination physical 1 1 1 Biochemical Activity
YDR042C YDR042C Putative protein of unknown function physical 1 1 1 Biochemical Activity
ZRG17 YNR039C Endoplasmic reticulum zinc transporter physical 1 1 1 Biochemical Activity
PXL1 YKR090W Protein that localizes to sites of polarized growth physical 1 1 1 Biochemical Activity
POX1 YGL205W Fatty-acyl coenzyme A oxidase physical 1 1 1 Biochemical Activity
TPK1 YJL164C cAMP-dependent protein kinase catalytic subunit physical 1 1 1 Biochemical Activity
SSD1 YDR293C Translational repressor physical 1 1 1 Biochemical Activity
YGR266W YGR266W Protein of unknown function physical 1 1 1 Biochemical Activity
WHI5 YOR083W Repressor of G1 transcription physical 1 1 1 Biochemical Activity
SPO7 YAL009W Putative regulatory subunit of Nem1p-Spo7p phosphatase holoenzyme physical 1 1 1 Biochemical Activity
VHS2 YIL135C Regulator of septin dynamics physical 1 1 1 Biochemical Activity
SIP5 YMR140W Protein of unknown function physical 1 1 1 Biochemical Activity
YJL070C YJL070C Putative metallo-dependent hydrolase superfamily protein physical 1 1 1 Biochemical Activity
ZUO1 YGR285C Ribosome-associated chaperone physical 1 1 1 Biochemical Activity
TPO1 YLL028W Polyamine transporter of the major facilitator superfamily physical 1 1 1 Biochemical Activity
SRP40 YKR092C Nucleolar serine-rich protein physical 1 1 1 Biochemical Activity
YPK3 YBR028C AGC kinase physical 1 1 1 Biochemical Activity
SOL2 YCR073W-A Protein with a possible role in tRNA export physical 1 1 1 Biochemical Activity
SKG1 YKR100C Transmembrane protein with a role in cell wall polymer composition physical 1 1 1 Biochemical Activity
TPK3 YKL166C cAMP-dependent protein kinase catalytic subunit physical 1 1 1 Biochemical Activity
SET5 YHR207C Methyltransferase involved in methylation of histone H4 Lys5, -8, -12 physical 1 1 1 Biochemical Activity
SEG1 YMR086W Component of eisosome required for proper eisosome assembly physical 1 1 1 Biochemical Activity
SMX2 YFL017W-A Core Sm protein Sm G physical 1 1 1 Biochemical Activity
SNX41 YDR425W Sorting nexin physical 1 1 1 Biochemical Activity
PTK2 YJR059W Serine/threonine protein kinase physical 1 1 1 Biochemical Activity
UBP10 YNL186W Ubiquitin-specific protease, deubiquitinates Ub-protein moieties physical 1 1 1 Biochemical Activity
YPT35 YHR105W Endosomal protein of unknown function physical 1 1 1 Biochemical Activity
YIF1 YNL263C Integral membrane protein physical 1 1 1 Biochemical Activity
PRR1 YKL116C Serine/threonine protein kinase physical 1 1 1 Biochemical Activity
UTR1 YJR049C ATP-NADH kinase physical 1 1 1 Biochemical Activity
SMY1 YKL079W Kinesin-like myosin passenger-protein physical 1 1 1 Biochemical Activity
TPK2 YPL203W cAMP-dependent protein kinase catalytic subunit physical 1 1 1 Biochemical Activity
YMR196W YMR196W Putative protein of unknown function physical 1 1 1 Biochemical Activity
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p physical 1 1 1 Affinity Capture-MS
PUF3 YLL013C Protein of the mitochondrial outer surface physical 1 1 1 Affinity Capture-RNA
SSC1 YJR045C Hsp70 family ATPase physical 1 1 1 Affinity Capture-MS
TOM22 YNL131W Component of the TOM (Translocase of Outer Membrane) complex physical 1 1 1 Affinity Capture-MS
RAD9 YDR217C DNA damage-dependent checkpoint protein genetic 1 1 1 Phenotypic Enhancement
RRI1 YDL216C Catalytic subunit of the COP9 signalosome (CSN) complex genetic 1 1 1 Negative Genetic
TMS1 YDR105C Vacuolar membrane protein of unknown function genetic 1 1 1 Negative Genetic
SSY1 YDR160W Component of the SPS plasma membrane amino acid sensor system genetic 1 1 1 Negative Genetic
STL1 YDR536W Glycerol proton symporter of the plasma membrane genetic 1 1 1 Negative Genetic
SIR2 YDL042C Conserved NAD+ dependent histone deacetylase of the Sirtuin family genetic 1 1 1 Synthetic Growth Defect
SCS7 YMR272C Sphingolipid alpha-hydroxylase genetic 1 1 1 Negative Genetic
SLX8 YER116C Subunit of Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex genetic 1 1 1 Positive Genetic
RPC25 YKL144C RNA polymerase III subunit C25 genetic 1 1 1 Positive Genetic
RSM19 YNR037C Mitochondrial ribosomal protein of the small subunit genetic 1 1 1 Positive Genetic
PRP24 YMR268C Splicing factor that reanneals snRNPs during spliceosome recycling genetic 1 1 1 Negative Genetic
STP22 YCL008C Component of the ESCRT-I complex genetic 1 1 1 Negative Genetic
SSN8 YNL025C Cyclin-like component of RNA polymerase II holoenzyme genetic 1 1 1 Negative Genetic
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 1 1 1 Positive Genetic
NCR1 YPL006W Vacuolar membrane protein involved with Npc2p in sterol trafficking physical 1 1 1 Biochemical Activity
MTM1 YGR257C Mitochondrial protein of the mitochondrial carrier family physical 1 1 1 Biochemical Activity
MAM1 YER106W Monopolin genetic 1 1 1 Negative Genetic
CDC8 YJR057W Nucleoside monophosphate and nucleoside diphosphate kinase genetic 1 1 1 Negative Genetic
OAR1 YKL055C Mitochondrial 3-oxoacyl-[acyl-carrier-protein] reductase genetic 1 1 1 Negative Genetic