ATG13 |
YPR185W |
Regulatory subunit of the Atg1p signaling complex |
physical |
34 |
6 |
25 |
Two-hybrid, Affinity Capture-Western, Reconstituted Complex, Two-hybrid, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Co-purification, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Biochemical Activity |
ATG11 |
YPR049C |
Adapter protein for pexophagy and the Cvt targeting pathway |
physical |
14 |
3 |
11 |
Two-hybrid, Affinity Capture-Western, Two-hybrid, Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS |
ATG17 |
YLR423C |
Scaffold protein responsible for phagophore assembly site organization |
physical |
13 |
3 |
11 |
Affinity Capture-Western, Two-hybrid, Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS |
ATG1 |
YGL180W |
Protein serine/threonine kinase |
physical |
7 |
4 |
7 |
Reconstituted Complex, Two-hybrid, Biochemical Activity, Biochemical Activity, Affinity Capture-Western, Two-hybrid, Biochemical Activity |
ATG8 |
YBL078C |
Ub-like protein |
physical |
7 |
6 |
6 |
Biochemical Activity, Two-hybrid, Affinity Capture-Western, Co-purification, Affinity Capture-Western, Co-localization, Affinity Capture-MS |
ATG31 |
YDR022C |
Autophagy-specific protein required for autophagosome formation |
physical |
5 |
3 |
4 |
Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-purification |
ATG13 |
YPR185W |
Regulatory subunit of the Atg1p signaling complex |
genetic |
4 |
4 |
4 |
Dosage Rescue, Phenotypic Enhancement, Phenotypic Suppression, Positive Genetic |
ATG9 |
YDL149W |
Transmembrane protein involved in forming Cvt and autophagic vesicles |
physical |
4 |
4 |
3 |
Affinity Capture-Western, Co-fractionation, Biochemical Activity, Co-localization |
ATG19 |
YOL082W |
Receptor protein for the cytoplasm-to-vacuole targeting (Cvt) pathway |
physical |
4 |
3 |
3 |
Affinity Capture-MS, Affinity Capture-Western, Biochemical Activity, Biochemical Activity |
ATG29 |
YPL166W |
Autophagy-specific protein |
physical |
4 |
2 |
3 |
Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS |
NAP1 |
YKR048C |
Histone chaperone and assembly chaperone for Rps6a/b |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
ENT5 |
YDR153C |
Protein containing an N-terminal epsin-like domain |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
YAP1 |
YML007W |
Basic leucine zipper (bZIP) transcription factor |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
PAT1 |
YCR077C |
Deadenylation-dependent mRNA-decapping factor |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
ECM1 |
YAL059W |
Pre-ribosomal factor involved in 60S ribosomal protein subunit export |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
RGD1 |
YBR260C |
GTPase-activating protein (RhoGAP) for Rho3p and Rho4p |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
FMP45 |
YDL222C |
Integral membrane protein localized to mitochondria |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
PEX5 |
YDR244W |
Peroxisomal membrane signal receptor for peroxisomal matrix proteins |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
FAR7 |
YFR008W |
Protein involved in recovery from pheromone-induced cell cycle arrest |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
DAP2 |
YHR028C |
Dipeptidyl aminopeptidase |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
GGA2 |
YHR108W |
Protein that regulates Arf1p, Arf2p to facilitate Golgi trafficking |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
AVL9 |
YLR114C |
Conserved protein involved in exocytic transport from the Golgi |
genetic |
4 |
1 |
3 |
Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic |
ERF2 |
YLR246W |
Subunit of a palmitoyltransferase |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
CIN4 |
YMR138W |
GTP-binding protein involved in beta-tubulin (Tub2p) folding |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
PDE2 |
YOR360C |
High-affinity cyclic AMP phosphodiesterase |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
FCY1 |
YPR062W |
Cytosine deaminase |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
SEC2 |
YNL272C |
Guanyl-nucleotide exchange factor for the small G-protein Sec4p |
physical |
3 |
2 |
3 |
Biochemical Activity, Two-hybrid, Two-hybrid |
PEX3 |
YDR329C |
Peroxisomal membrane protein (PMP) |
genetic |
3 |
2 |
3 |
Phenotypic Enhancement, Phenotypic Enhancement, Negative Genetic |
DGR2 |
YKL121W |
Protein of unknown function |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
ORC2 |
YBR060C |
Subunit of the origin recognition complex (ORC) |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
YBR225W |
YBR225W |
Putative protein of unknown function |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
ICL1 |
YER065C |
Isocitrate lyase |
genetic |
3 |
1 |
3 |
Positive Genetic, Positive Genetic, Positive Genetic |
BCK2 |
YER167W |
Serine/threonine-rich protein involved in PKC1 signaling pathway |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
BYE1 |
YKL005C |
Negative regulator of transcription elongation |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
EMP46 |
YLR080W |
Integral membrane component of ER-derived COPII-coated vesicles |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
PFK2 |
YMR205C |
Beta subunit of heterooctameric phosphofructokinase |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
CUR1 |
YPR158W |
Sorting factor, central regulator of spatial protein quality control |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
SPR3 |
YGR059W |
Sporulation-specific homolog of the CDC3/10/11/12 family of genes |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
BCY1 |
YIL033C |
Regulatory subunit of the cyclic AMP-dependent protein kinase (PKA) |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
SOP4 |
YJL192C |
ER-membrane protein |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
LSM1 |
YJL124C |
Lsm (Like Sm) protein |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
CPR3 |
YML078W |
Mitochondrial peptidyl-prolyl cis-trans isomerase (cyclophilin) |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
BOR1 |
YNL275W |
Boron efflux transporter of the plasma membrane |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
PSH1 |
YOL054W |
E3 ubiquitin ligase targeting centromere-binding protein Cse4p |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
HIR2 |
YOR038C |
Subunit of HIR nucleosome assembly complex |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
APE1 |
YKL103C |
Vacuolar aminopeptidase yscI |
physical |
3 |
3 |
2 |
Affinity Capture-Western, Affinity Capture-MS, Reconstituted Complex |
YPT1 |
YFL038C |
Rab family GTPase |
physical |
3 |
2 |
2 |
Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western |
RIM15 |
YFL033C |
Protein kinase involved in cell proliferation in response to nutrients |
genetic |
3 |
1 |
2 |
Positive Genetic, Positive Genetic, Positive Genetic |
VID28 |
YIL017C |
GID Complex subunit, serves as adaptor for regulatory subunit Vid24p |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
RQT4 |
YKR023W |
Subunit of ribosome-associated quality control trigger complex (RQT) |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
GLR1 |
YPL091W |
Cytosolic and mitochondrial glutathione oxidoreductase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
TYE7 |
YOR344C |
Serine-rich protein that contains a bHLH DNA binding motif |
physical |
2 |
2 |
2 |
Biochemical Activity, Two-hybrid |
NOP53 |
YPL146C |
Nucleolar protein |
physical |
2 |
2 |
2 |
Biochemical Activity, Two-hybrid |
ATG8 |
YBL078C |
Ub-like protein |
genetic |
2 |
2 |
2 |
Phenotypic Enhancement, Phenotypic Suppression |
SSD1 |
YDR293C |
Translational repressor |
physical |
2 |
2 |
2 |
Biochemical Activity, Affinity Capture-RNA |
IPI3 |
YNL182C |
Component of the Rix1 complex and pre-replicative complexes (pre-RCs) |
physical |
2 |
2 |
2 |
Biochemical Activity, Two-hybrid |
SSO1 |
YPL232W |
Plasma membrane t-SNARE |
genetic |
2 |
2 |
2 |
Phenotypic Suppression, Negative Genetic |
ATG4 |
YNL223W |
Conserved cysteine protease required for autophagy |
genetic |
2 |
2 |
2 |
Phenotypic Enhancement, Positive Genetic |
SNF1 |
YDR477W |
AMP-activated S/T protein kinase |
genetic |
2 |
2 |
2 |
Dosage Rescue, Positive Genetic |
SSN3 |
YPL042C |
Component of the RNA polymerase II mediator complex |
genetic |
2 |
2 |
2 |
Positive Genetic, Negative Genetic |
PEP4 |
YPL154C |
Vacuolar aspartyl protease (proteinase A) |
genetic |
2 |
2 |
2 |
Phenotypic Enhancement, Negative Genetic |
SLT2 |
YHR030C |
Serine/threonine MAP kinase |
genetic |
2 |
2 |
2 |
Phenotypic Enhancement, Dosage Growth Defect |
KSP1 |
YHR082C |
Serine/threonine protein kinase |
genetic |
2 |
2 |
2 |
Negative Genetic, Phenotypic Suppression |
ATG27 |
YJL178C |
Type I membrane protein involved in autophagy and the Cvt pathway |
genetic |
2 |
2 |
2 |
Phenotypic Enhancement, Positive Genetic |
ATG10 |
YLL042C |
Conserved E2-like conjugating enzyme |
genetic |
2 |
2 |
2 |
Positive Genetic, Phenotypic Suppression |
ATG15 |
YCR068W |
Phospholipase |
genetic |
2 |
2 |
2 |
Positive Genetic, Phenotypic Suppression |
ATG7 |
YHR171W |
Autophagy-related protein and dual specificity member of the E1 family |
genetic |
2 |
2 |
2 |
Positive Genetic, Phenotypic Suppression |
GPI8 |
YDR331W |
Catalytic subunit of the ER membrane GPI transamidase complex |
genetic |
2 |
2 |
2 |
Dosage Growth Defect, Synthetic Lethality |
HYP2 |
YEL034W |
Translation elongation factor eIF-5A |
genetic |
2 |
2 |
2 |
Synthetic Rescue, Positive Genetic |
NUP116 |
YMR047C |
FG-nucleoporin component of central core of the nuclear pore complex |
genetic |
2 |
2 |
2 |
Negative Genetic, Phenotypic Enhancement |
ATG11 |
YPR049C |
Adapter protein for pexophagy and the Cvt targeting pathway |
genetic |
2 |
1 |
2 |
Phenotypic Enhancement, Phenotypic Enhancement |
MSP1 |
YGR028W |
Highly-conserved N-terminally anchored AAA-ATPase |
physical |
2 |
1 |
2 |
Biochemical Activity, Biochemical Activity |
CDC3 |
YLR314C |
Component of the septin ring that is required for cytokinesis |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
2 |
1 |
2 |
Affinity Capture-RNA, Affinity Capture-RNA |
ATG14 |
YBR128C |
Autophagy-specific subunit of phosphatidylinositol 3-kinase complex I |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
CMP2 |
YML057W |
Calcineurin A |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
MTW1 |
YAL034W-A |
Essential component of the MIND kinetochore complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
COP1 |
YDL145C |
Alpha subunit of COPI vesicle coatomer complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
TSC13 |
YDL015C |
Enoyl reductase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RVS167 |
YDR388W |
Calmodulin-binding actin-associated protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
WBP1 |
YEL002C |
Beta subunit of the oligosaccharyl transferase glycoprotein complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SEC3 |
YER008C |
Subunit of the exocyst complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
EMC10 |
YDR056C |
Putative protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PEX8 |
YGR077C |
Intraperoxisomal organizer of the peroxisomal import machinery |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
EGD2 |
YHR193C |
Alpha subunit of the nascent polypeptide-associated complex (NAC) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
IME2 |
YJL106W |
Serine/threonine protein kinase involved in activation of meiosis |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
YJR154W |
YJR154W |
Putative protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
LOT5 |
YKL183W |
Protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
YKL063C |
YKL063C |
Putative protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
OPY2 |
YPR075C |
Integral membrane protein that acts as a membrane anchor for Ste50p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RPS25A |
YGR027C |
Protein component of the small (40S) ribosomal subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ERG11 |
YHR007C |
Lanosterol 14-alpha-demethylase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SYS1 |
YJL004C |
Integral membrane protein of the Golgi |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
AUR1 |
YKL004W |
Phosphatidylinositol:ceramide phosphoinositol transferase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
KAE1 |
YKR038C |
Highly conserved ATPase of HSP70/DnaK family |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SGD1 |
YLR336C |
Essential nuclear protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PGA3 |
YML125C |
Putative cytochrome b5 reductase, localized to the plasma membrane |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SCS7 |
YMR272C |
Sphingolipid alpha-hydroxylase |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
SIN4 |
YNL236W |
Subunit of the RNA polymerase II mediator complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
HXT17 |
YNR072W |
Putative transmembrane polyol transporter |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SKI7 |
YOR076C |
GTP-binding protein that couples the Ski complex and exosome |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
DFR1 |
YOR236W |
Dihydrofolate reductase involved in tetrahydrofolate biosynthesis |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
FAS2 |
YPL231W |
Alpha subunit of fatty acid synthetase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
NIP7 |
YPL211W |
Nucleolar protein required for 60S ribosome subunit biogenesis |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
VPS4 |
YPR173C |
AAA-ATPase involved in multivesicular body (MVB) protein sorting |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PKH1 |
YDR490C |
Serine/threonine protein kinase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
KDX1 |
YKL161C |
Protein kinase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ATG4 |
YNL223W |
Conserved cysteine protease required for autophagy |
physical |
2 |
2 |
1 |
Biochemical Activity, PCA |
ATG5 |
YPL149W |
Conserved protein involved in autophagy and the Cvt pathway |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
MEC1 |
YBR136W |
Genome integrity checkpoint protein and PI kinase superfamily member |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
PSP2 |
YML017W |
Asn rich cytoplasmic protein that contains RGG motifs |
physical |
2 |
2 |
1 |
Affinity Capture-RNA, Protein-RNA |
MCD4 |
YKL165C |
Protein involved in GPI anchor synthesis |
genetic |
2 |
1 |
1 |
Synthetic Rescue, Synthetic Rescue |
MET32 |
YDR253C |
Zinc-finger DNA-binding transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
MET4 |
YNL103W |
Leucine-zipper transcriptional activator |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RGR1 |
YLR071C |
Subunit of the RNA polymerase II mediator complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
GCN4 |
YEL009C |
bZIP transcriptional activator of amino acid biosynthetic genes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
CTR9 |
YOL145C |
Component of the Paf1p complex involved in transcription elongation |
regulation |
1 |
1 |
1 |
quantitative reverse transcription polymerase chain reaction evidence |
PAF1 |
YBR279W |
Component of the Paf1p complex involved in transcription elongation |
regulation |
1 |
1 |
1 |
quantitative reverse transcription polymerase chain reaction evidence |
RTF1 |
YGL244W |
Subunit of RNAPII-associated chromatin remodeling Paf1 complex |
regulation |
1 |
1 |
1 |
quantitative reverse transcription polymerase chain reaction evidence |
PTC2 |
YER089C |
Type 2C protein phosphatase (PP2C) |
regulation |
1 |
1 |
1 |
qualitative western immunoblotting evidence |
ATG1 |
YGL180W |
Protein serine/threonine kinase |
regulation |
1 |
1 |
1 |
protein kinase assay evidence |
ATG19 |
YOL082W |
Receptor protein for the cytoplasm-to-vacuole targeting (Cvt) pathway |
regulation |
1 |
1 |
1 |
protein kinase assay evidence |
ATG34 |
YOL083W |
Receptor protein involved in selective autophagy during starvation |
regulation |
1 |
1 |
1 |
protein kinase assay evidence |
YKT6 |
YKL196C |
Vesicle membrane protein (v-SNARE) with acyltransferase activity |
regulation |
1 |
1 |
1 |
protein kinase assay evidence |
PTC3 |
YBL056W |
Type 2C protein phosphatase (PP2C) |
regulation |
1 |
1 |
1 |
qualitative western immunoblotting evidence |
AME1 |
YBR211C |
Essential kinetochore protein associated with microtubules and SPBs |
genetic |
1 |
1 |
1 |
Negative Genetic |
AIM25 |
YJR100C |
Mitochondria protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ARC1 |
YGL105W |
Protein that binds tRNA and methionyl- and glutamyl-tRNA synthetases |
physical |
1 |
1 |
1 |
Biochemical Activity |
ARP2 |
YDL029W |
Essential component of the Arp2/3 complex |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
AIM21 |
YIR003W |
Subunit of a complex that associates with actin filaments |
physical |
1 |
1 |
1 |
Biochemical Activity |
ARP8 |
YOR141C |
Nuclear actin-related protein involved in chromatin remodeling |
physical |
1 |
1 |
1 |
Biochemical Activity |
ADO1 |
YJR105W |
Adenosine kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
APP1 |
YNL094W |
Phosphatidate phosphatase, converts phosphatidate to diacylglycerol |
physical |
1 |
1 |
1 |
Biochemical Activity |
ARE2 |
YNR019W |
Acyl-CoA:sterol acyltransferase |
physical |
1 |
1 |
1 |
Biochemical Activity |
ADE6 |
YGR061C |
Formylglycinamidine-ribonucleotide (FGAM)-synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ALR1 |
YOL130W |
Plasma membrane Mg(2+) transporter |
physical |
1 |
1 |
1 |
Biochemical Activity |
ATG17 |
YLR423C |
Scaffold protein responsible for phagophore assembly site organization |
genetic |
1 |
1 |
1 |
Positive Genetic |
UBP11 |
YKR098C |
Ubiquitin-specific protease |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SIP2 |
YGL208W |
One of three alternate beta subunits of the Snf1 kinase complex |
physical |
1 |
1 |
1 |
Biochemical Activity |
SIP2 |
YGL208W |
One of three alternate beta subunits of the Snf1 kinase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
TOM71 |
YHR117W |
Mitochondrial outer membrane protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
OTU2 |
YHL013C |
Protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
BIR1 |
YJR089W |
Subunit of chromosomal passenger complex (CPC) |
physical |
1 |
1 |
1 |
Biochemical Activity |
OSH3 |
YHR073W |
Member of an oxysterol-binding protein family |
physical |
1 |
1 |
1 |
Biochemical Activity |
ATG18 |
YFR021W |
Phosphoinositide binding protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
ATG18 |
YFR021W |
Phosphoinositide binding protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
LEO1 |
YOR123C |
Component of the Paf1 complex |
physical |
1 |
1 |
1 |
Biochemical Activity |
RTK1 |
YDL025C |
Putative protein kinase, potentially phosphorylated by Cdc28p |
physical |
1 |
1 |
1 |
Biochemical Activity |
RTK1 |
YDL025C |
Putative protein kinase, potentially phosphorylated by Cdc28p |
genetic |
1 |
1 |
1 |
Positive Genetic |
ERB1 |
YMR049C |
Constituent of 66S pre-ribosomal particles |
physical |
1 |
1 |
1 |
Biochemical Activity |
PAH1 |
YMR165C |
Mg2+-dependent phosphatidate (PA) phosphatase |
physical |
1 |
1 |
1 |
Biochemical Activity |
ELF1 |
YKL160W |
Transcription elongation factor with a conserved zinc finger domain |
physical |
1 |
1 |
1 |
Biochemical Activity |
PTR3 |
YFR029W |
Component of the SPS plasma membrane amino acid sensor system |
physical |
1 |
1 |
1 |
Biochemical Activity |
AVT3 |
YKL146W |
Vacuolar transporter |
physical |
1 |
1 |
1 |
Biochemical Activity |
YNL284C-A |
YNL284C-A |
Retrotransposon TYA Gag gene co-transcribed with TYB Pol |
physical |
1 |
1 |
1 |
Biochemical Activity |
YGR038C-A |
YGR038C-A |
Retrotransposon TYA Gag gene co-transcribed with TYB Pol |
physical |
1 |
1 |
1 |
Biochemical Activity |
SEC2 |
YNL272C |
Guanyl-nucleotide exchange factor for the small G-protein Sec4p |
genetic |
1 |
1 |
1 |
Negative Genetic |
PGA2 |
YNL149C |
Essential protein required for maturation of Gas1p and Pho8p |
physical |
1 |
1 |
1 |
Biochemical Activity |
MIG2 |
YGL209W |
Zinc finger transcriptional repressor |
physical |
1 |
1 |
1 |
Biochemical Activity |
TFC6 |
YDR362C |
Subunit of RNA polymerase III transcription initiation factor complex |
physical |
1 |
1 |
1 |
Biochemical Activity |
YDR239C |
YDR239C |
Protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
NAP1 |
YKR048C |
Histone chaperone and assembly chaperone for Rps6a/b |
physical |
1 |
1 |
1 |
Biochemical Activity |
LRP1 |
YHR081W |
Nuclear exosome-associated nucleic acid binding protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
STP3 |
YLR375W |
Zinc-finger protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
SPO21 |
YOL091W |
Component of the meiotic outer plaque of the spindle pole body |
physical |
1 |
1 |
1 |
Biochemical Activity |
NCL1 |
YBL024W |
S-adenosyl-L-methionine-dependent tRNA: m5C-methyltransferase |
physical |
1 |
1 |
1 |
Biochemical Activity |
NBA1 |
YOL070C |
Protein involved in axial bud site selection |
physical |
1 |
1 |
1 |
Biochemical Activity |
TES1 |
YJR019C |
Peroxisomal acyl-CoA thioesterase |
physical |
1 |
1 |
1 |
Biochemical Activity |
YHR214C-C |
YHR214C-C |
Retrotransposon TYA Gag gene co-transcribed with TYB Pol |
physical |
1 |
1 |
1 |
Biochemical Activity |
ATG21 |
YPL100W |
Phosphoinositide binding protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
DED1 |
YOR204W |
ATP-dependent DEAD-box RNA helicase with strand-annealing activity |
physical |
1 |
1 |
1 |
Biochemical Activity |
SSF2 |
YDR312W |
Protein required for ribosomal large subunit maturation |
physical |
1 |
1 |
1 |
Biochemical Activity |
SRP40 |
YKR092C |
Nucleolar serine-rich protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
RPS26B |
YER131W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Biochemical Activity |
DDR48 |
YMR173W |
DNA damage-responsive protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
MGA1 |
YGR249W |
Protein similar to heat shock transcription factor |
physical |
1 |
1 |
1 |
Biochemical Activity |
YKR041W |
YKR041W |
Protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
KXD1 |
YGL079W |
Subunit of the BLOC-1 complex involved in endosomal maturation |
physical |
1 |
1 |
1 |
Biochemical Activity |
YNG2 |
YHR090C |
Subunit of NuA4, an essential histone acetyltransferase complex |
physical |
1 |
1 |
1 |
Biochemical Activity |
HEK2 |
YBL032W |
RNA binding protein involved in asymmetric localization of ASH1 mRNA |
physical |
1 |
1 |
1 |
Biochemical Activity |
LIN1 |
YHR156C |
Non-essential component of U5 snRNP |
physical |
1 |
1 |
1 |
Biochemical Activity |
HAS1 |
YMR290C |
ATP-dependent RNA helicase |
physical |
1 |
1 |
1 |
Biochemical Activity |
ENT5 |
YDR153C |
Protein containing an N-terminal epsin-like domain |
physical |
1 |
1 |
1 |
Biochemical Activity |
LSB3 |
YFR024C-A |
Protein containing a C-terminal SH3 domain |
physical |
1 |
1 |
1 |
Biochemical Activity |
LSB3 |
YFR024C-A |
Protein containing a C-terminal SH3 domain |
genetic |
1 |
1 |
1 |
Negative Genetic |
IRC5 |
YFR038W |
Putative ATPase containing the DEAD/H helicase-related sequence motif |
physical |
1 |
1 |
1 |
Biochemical Activity |
UBP10 |
YNL186W |
Ubiquitin-specific protease, deubiquitinates Ub-protein moieties |
physical |
1 |
1 |
1 |
Biochemical Activity |
PRC1 |
YMR297W |
Vacuolar carboxypeptidase Y (proteinase C, CPY) |
physical |
1 |
1 |
1 |
Biochemical Activity |
CWC25 |
YNL245C |
Splicing factor required for the first step of pre-mRNA splicing |
physical |
1 |
1 |
1 |
Biochemical Activity |
YGR126W |
YGR126W |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
AVO1 |
YOL078W |
Component of the membrane-bound TORC2 complex |
physical |
1 |
1 |
1 |
Biochemical Activity |
DRE2 |
YKR071C |
Component of the cytosolic Fe-S protein assembly (CIA) machinery |
physical |
1 |
1 |
1 |
Biochemical Activity |
CRZ1 |
YNL027W |
Transcription factor, activates transcription of stress response genes |
physical |
1 |
1 |
1 |
Biochemical Activity |
BDF2 |
YDL070W |
Protein involved in transcription initiation |
physical |
1 |
1 |
1 |
Biochemical Activity |
YAP3 |
YHL009C |
Basic leucine zipper (bZIP) transcription factor |
physical |
1 |
1 |
1 |
Biochemical Activity |
RSP5 |
YER125W |
NEDD4 family E3 ubiquitin ligase |
physical |
1 |
1 |
1 |
Biochemical Activity |
YBL055C |
YBL055C |
3'-->5' exonuclease and endonuclease with a possible role in apoptosis |
physical |
1 |
1 |
1 |
Biochemical Activity |
SCT1 |
YBL011W |
Glycerol 3-phosphate/dihydroxyacetone phosphate sn-1 acyltransferase |
physical |
1 |
1 |
1 |
Biochemical Activity |
IWR1 |
YDL115C |
RNA polymerase II transport factor, conserved from yeast to humans |
physical |
1 |
1 |
1 |
Biochemical Activity |
YPR158W-A |
YPR158W-A |
Retrotransposon TYA Gag gene co-transcribed with TYB Pol |
physical |
1 |
1 |
1 |
Biochemical Activity |
YNL165W |
YNL165W |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
BUD4 |
YJR092W |
Anillin-like protein involved in bud-site selection |
physical |
1 |
1 |
1 |
Biochemical Activity |
DBP9 |
YLR276C |
DEAD-box protein required for 27S rRNA processing |
physical |
1 |
1 |
1 |
Biochemical Activity |
RPA34 |
YJL148W |
RNA polymerase I subunit A34.5 |
physical |
1 |
1 |
1 |
Biochemical Activity |
MDG1 |
YNL173C |
Plasma membrane protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
CTI6 |
YPL181W |
Component of the Rpd3L histone deacetylase complex |
physical |
1 |
1 |
1 |
Biochemical Activity |
SLX5 |
YDL013W |
Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex |
physical |
1 |
1 |
1 |
Biochemical Activity |
UBP6 |
YFR010W |
Ubiquitin-specific protease |
physical |
1 |
1 |
1 |
Biochemical Activity |
ELM1 |
YKL048C |
Serine/threonine protein kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
STB3 |
YDR169C |
Ribosomal RNA processing element (RRPE)-binding protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
HRP1 |
YOL123W |
Subunit of cleavage factor I |
physical |
1 |
1 |
1 |
Biochemical Activity |
RPL40B |
YKR094C |
Ubiquitin-ribosomal 60S subunit protein L40B fusion protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
PDE1 |
YGL248W |
Low-affinity cyclic AMP phosphodiesterase |
physical |
1 |
1 |
1 |
Biochemical Activity |
CRN1 |
YLR429W |
Coronin |
physical |
1 |
1 |
1 |
Biochemical Activity |
CRN1 |
YLR429W |
Coronin |
genetic |
1 |
1 |
1 |
Negative Genetic |
VHS3 |
YOR054C |
Negative regulatory subunit of protein phosphatase 1 Ppz1p |
physical |
1 |
1 |
1 |
Biochemical Activity |
YDR034C-C |
YDR034C-C |
Retrotransposon TYA Gag gene co-transcribed with TYB Pol |
physical |
1 |
1 |
1 |
Biochemical Activity |
YGR027W-A |
YGR027W-A |
Retrotransposon TYA Gag gene co-transcribed with TYB Pol |
physical |
1 |
1 |
1 |
Biochemical Activity |
IRC4 |
YDR540C |
Protein similar to bacterial secreted DfsB proteins |
physical |
1 |
1 |
1 |
Biochemical Activity |
DEG1 |
YFL001W |
tRNA:pseudouridine synthase |
physical |
1 |
1 |
1 |
Biochemical Activity |
YOL103W-A |
YOL103W-A |
Retrotransposon TYA Gag gene co-transcribed with TYB Pol |
physical |
1 |
1 |
1 |
Biochemical Activity |
NVJ2 |
YPR091C |
Lipid-binding ER protein, enriched at nucleus-vacuolar junctions (NVJ) |
physical |
1 |
1 |
1 |
Biochemical Activity |
LEU3 |
YLR451W |
Zinc-knuckle transcription factor, repressor and activator |
physical |
1 |
1 |
1 |
Biochemical Activity |
HCA4 |
YJL033W |
DEAD box RNA helicase |
physical |
1 |
1 |
1 |
Biochemical Activity |
DGR2 |
YKL121W |
Protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
MCM4 |
YPR019W |
Essential helicase component of heterohexameric MCM2-7 complexes |
physical |
1 |
1 |
1 |
Biochemical Activity |
LCP5 |
YER127W |
Essential protein involved in maturation of 18S rRNA |
physical |
1 |
1 |
1 |
Biochemical Activity |
BIK1 |
YCL029C |
Microtubule-associated protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
UBP7 |
YIL156W |
Ubiquitin-specific protease that cleaves ubiquitin-protein fusions |
physical |
1 |
1 |
1 |
Biochemical Activity |
WHI5 |
YOR083W |
Repressor of G1 transcription |
physical |
1 |
1 |
1 |
Biochemical Activity |
VPS55 |
YJR044C |
Late endosomal protein involved in late endosome to vacuole transport |
physical |
1 |
1 |
1 |
Biochemical Activity |
YLR125W |
YLR125W |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
BUD3 |
YCL014W |
Guanine nucleotide exchange factor (GEF) for Cdc42p |
physical |
1 |
1 |
1 |
Biochemical Activity |
SIP5 |
YMR140W |
Protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
YAP1 |
YML007W |
Basic leucine zipper (bZIP) transcription factor |
physical |
1 |
1 |
1 |
Biochemical Activity |
SAS10 |
YDL153C |
Subunit of U3-containing Small Subunit (SSU) processome complex |
physical |
1 |
1 |
1 |
Biochemical Activity |
PHO4 |
YFR034C |
Basic helix-loop-helix (bHLH) transcription factor of the myc-family |
physical |
1 |
1 |
1 |
Biochemical Activity |
RDS2 |
YPL133C |
Transcription factor involved in regulating gluconeogenesis |
physical |
1 |
1 |
1 |
Biochemical Activity |
LRS4 |
YDR439W |
Nucleolar protein that forms a complex with Csm1p |
physical |
1 |
1 |
1 |
Biochemical Activity |
ORM2 |
YLR350W |
Protein that mediates sphingolipid homeostasis |
physical |
1 |
1 |
1 |
Biochemical Activity |
YKR045C |
YKR045C |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
UBP9 |
YER098W |
Ubiquitin-specific protease that cleaves ubiquitin-protein fusions |
physical |
1 |
1 |
1 |
Biochemical Activity |
UBX5 |
YDR330W |
UBX domain-containing protein that interacts with Cdc48p |
physical |
1 |
1 |
1 |
Biochemical Activity |
YPR158C-C |
YPR158C-C |
Retrotransposon TYA Gag gene co-transcribed with TYB Pol |
physical |
1 |
1 |
1 |
Biochemical Activity |
PDS1 |
YDR113C |
Securin |
physical |
1 |
1 |
1 |
Biochemical Activity |
YML037C |
YML037C |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
SPC42 |
YKL042W |
Central plaque component of spindle pole body (SPB) |
physical |
1 |
1 |
1 |
Biochemical Activity |
SPC42 |
YKL042W |
Central plaque component of spindle pole body (SPB) |
genetic |
1 |
1 |
1 |
Negative Genetic |
ESBP6 |
YNL125C |
Protein with similarity to monocarboxylate permeases |
physical |
1 |
1 |
1 |
Biochemical Activity |
PFK26 |
YIL107C |
6-phosphofructo-2-kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
RRP15 |
YPR143W |
Nucleolar protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
RRP5 |
YMR229C |
RNA binding protein involved in synthesis of 18S and 5.8S rRNAs |
physical |
1 |
1 |
1 |
Biochemical Activity |
CMS1 |
YLR003C |
Putative subunit of the 90S preribosome processome complex |
physical |
1 |
1 |
1 |
Biochemical Activity |
NSR1 |
YGR159C |
Nucleolin, nucleolar protein that binds nuclear localization sequences |
physical |
1 |
1 |
1 |
Biochemical Activity |
SPO13 |
YHR014W |
Meiotic regulator |
physical |
1 |
1 |
1 |
Biochemical Activity |
FPS1 |
YLL043W |
Aquaglyceroporin, plasma membrane channel |
physical |
1 |
1 |
1 |
Biochemical Activity |
SCD6 |
YPR129W |
Repressor of translation initiation |
physical |
1 |
1 |
1 |
Biochemical Activity |
FRT2 |
YAL028W |
Tail-anchored ER membrane protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
JJJ1 |
YNL227C |
Co-chaperone that stimulates the ATPase activity of Ssa1p |
physical |
1 |
1 |
1 |
Biochemical Activity |
NOB1 |
YOR056C |
Protein involved in proteasomal and 40S ribosomal subunit biogenesis |
physical |
1 |
1 |
1 |
Biochemical Activity |
SPT16 |
YGL207W |
Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) |
physical |
1 |
1 |
1 |
Biochemical Activity |
YPR137C-A |
YPR137C-A |
Retrotransposon TYA Gag gene co-transcribed with TYB Pol |
physical |
1 |
1 |
1 |
Biochemical Activity |
YGR130C |
YGR130C |
Component of the eisosome with unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
MBR1 |
YKL093W |
Protein involved in mitochondrial functions and stress response |
physical |
1 |
1 |
1 |
Biochemical Activity |
SVF1 |
YDR346C |
Protein with a potential role in cell survival pathways |
physical |
1 |
1 |
1 |
Biochemical Activity |
CNS1 |
YBR155W |
TPR-containing co-chaperone |
physical |
1 |
1 |
1 |
Biochemical Activity |
DIA1 |
YMR316W |
Protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
CWC24 |
YLR323C |
General splicing factor |
physical |
1 |
1 |
1 |
Biochemical Activity |
YML045W-A |
YML045W-A |
Retrotransposon TYA Gag gene co-transcribed with TYB Pol |
physical |
1 |
1 |
1 |
Biochemical Activity |
YLR257W |
YLR257W |
Protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
DAL82 |
YNL314W |
Positive regulator of allophanate inducible genes |
physical |
1 |
1 |
1 |
Biochemical Activity |
YER034W |
YER034W |
Protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
GTT3 |
YEL017W |
Protein of unknown function may be involved in glutathione metabolism |
physical |
1 |
1 |
1 |
Biochemical Activity |
RGC1 |
YPR115W |
Putative regulator of the Fps1p glycerol channel |
physical |
1 |
1 |
1 |
Biochemical Activity |
RGC1 |
YPR115W |
Putative regulator of the Fps1p glycerol channel |
genetic |
1 |
1 |
1 |
Negative Genetic |
DPC29 |
YGR021W |
Putative mitochondrial protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
CDC13 |
YDL220C |
Single stranded DNA-binding protein found at TG1-3 telomere G-tails |
physical |
1 |
1 |
1 |
Biochemical Activity |
YNL054W-A |
YNL054W-A |
Retrotransposon TYA Gag gene co-transcribed with TYB Pol |
physical |
1 |
1 |
1 |
Biochemical Activity |
YPL257W-A |
YPL257W-A |
Retrotransposon TYA Gag gene co-transcribed with TYB Pol |
physical |
1 |
1 |
1 |
Biochemical Activity |
HCR1 |
YLR192C |
eIF3j component of translation initiation factor 3 (eIF3) |
physical |
1 |
1 |
1 |
Biochemical Activity |
NEJ1 |
YLR265C |
DNA end-binding protein required for nonhomologous end joining (NHEJ) |
physical |
1 |
1 |
1 |
Biochemical Activity |
GLO3 |
YER122C |
ADP-ribosylation factor GTPase activating protein (ARF GAP) |
physical |
1 |
1 |
1 |
Biochemical Activity |
DRS1 |
YLL008W |
Nucleolar DEAD-box protein required for ribosome assembly and function |
physical |
1 |
1 |
1 |
Biochemical Activity |
VIP1 |
YLR410W |
Bifunctional inositol pyrophosphate kinase and phosphatase |
physical |
1 |
1 |
1 |
Biochemical Activity |
RPA43 |
YOR340C |
RNA polymerase I subunit A43 |
physical |
1 |
1 |
1 |
Biochemical Activity |
BUD21 |
YOR078W |
Component of small ribosomal subunit (SSU) processosome |
physical |
1 |
1 |
1 |
Biochemical Activity |
LHP1 |
YDL051W |
RNA binding protein required for maturation of tRNA and U6 snRNA |
physical |
1 |
1 |
1 |
Biochemical Activity |
IES5 |
YER092W |
Non-essential INO80 chromatin remodeling complex subunit |
physical |
1 |
1 |
1 |
Biochemical Activity |
BMH2 |
YDR099W |
14-3-3 protein, minor isoform |
physical |
1 |
1 |
1 |
Biochemical Activity |
TDA3 |
YHR009C |
Putative oxidoreductase involved in late endosome to Golgi transport |
physical |
1 |
1 |
1 |
Biochemical Activity |
SKT5 |
YBL061C |
Activator of Chs3p (chitin synthase III) during vegetative growth |
physical |
1 |
1 |
1 |
Biochemical Activity |
KRS1 |
YDR037W |
Lysyl-tRNA synthetase |
physical |
1 |
1 |
1 |
Biochemical Activity |
YLR410W-A |
YLR410W-A |
Retrotransposon TYA Gag gene co-transcribed with TYB Pol |
physical |
1 |
1 |
1 |
Biochemical Activity |
YPT11 |
YNL304W |
Rab GTPase |
physical |
1 |
1 |
1 |
Biochemical Activity |
BUD27 |
YFL023W |
Unconventional prefoldin protein involved in translation initiation |
physical |
1 |
1 |
1 |
Biochemical Activity |
UTP25 |
YIL091C |
Nucleolar protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
MSS4 |
YDR208W |
Phosphatidylinositol-4-phosphate 5-kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
MAP1 |
YLR244C |
Methionine aminopeptidase |
physical |
1 |
1 |
1 |
Biochemical Activity |
HSH155 |
YMR288W |
U2-snRNP associated splicing factor |
physical |
1 |
1 |
1 |
Biochemical Activity |
MSB3 |
YNL293W |
Rab GTPase-activating protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
SKA1 |
YKL023W |
SKI complex-associated protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
MIL1 |
YFL034W |
Predicted lipase |
physical |
1 |
1 |
1 |
Biochemical Activity |
MFT1 |
YML062C |
Subunit of the THO complex |
physical |
1 |
1 |
1 |
Biochemical Activity |
IST2 |
YBR086C |
Cortical ER protein involved in ER-plasma membrane (PM) tethering |
physical |
1 |
1 |
1 |
Biochemical Activity |
SHE3 |
YBR130C |
Protein adaptor between Myo4p and the She2p-mRNA complex |
physical |
1 |
1 |
1 |
Biochemical Activity |
RIO1 |
YOR119C |
Serine kinase involved in cell cycle regulation and rDNA integrity |
physical |
1 |
1 |
1 |
Biochemical Activity |
CDC55 |
YGL190C |
Regulatory subunit B of protein phosphatase 2A (PP2A) |
physical |
1 |
1 |
1 |
Biochemical Activity |
NPA3 |
YJR072C |
Member of the conserved GPN-loop GTPase family |
physical |
1 |
1 |
1 |
Biochemical Activity |
LSM4 |
YER112W |
Lsm (Like Sm) protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
NAB3 |
YPL190C |
RNA-binding protein, subunit of Nrd1 complex (Nrd1p-Nab3p-Sen1p) |
physical |
1 |
1 |
1 |
Biochemical Activity |
BIT2 |
YBR270C |
Subunit of TORC2 membrane-associated complex |
physical |
1 |
1 |
1 |
Biochemical Activity |
RCI37 |
YIL077C |
Protein that associates with the large mitoribosomal subunit |
physical |
1 |
1 |
1 |
Biochemical Activity |
CHA4 |
YLR098C |
DNA binding transcriptional activator |
physical |
1 |
1 |
1 |
Biochemical Activity |
KNS1 |
YLL019C |
Protein kinase involved in negative regulation of PolIII transcription |
physical |
1 |
1 |
1 |
Biochemical Activity |
KNS1 |
YLL019C |
Protein kinase involved in negative regulation of PolIII transcription |
genetic |
1 |
1 |
1 |
Negative Genetic |
TPK3 |
YKL166C |
cAMP-dependent protein kinase catalytic subunit |
physical |
1 |
1 |
1 |
Biochemical Activity |
PKP2 |
YGL059W |
Mitochondrial protein kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
ATG29 |
YPL166W |
Autophagy-specific protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
NAB2 |
YGL122C |
Nuclear polyadenylated RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
GAL7 |
YBR018C |
Galactose-1-phosphate uridyl transferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PHO85 |
YPL031C |
Cyclin-dependent kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
HHT1 |
YBR010W |
Histone H3 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HHT2 |
YNL031C |
Histone H3 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CMR1 |
YDL156W |
Nuclear protein with role in transcription, protein quality control |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SPC72 |
YAL047C |
Gamma-tubulin small complex (gamma-TuSC) receptor |
physical |
1 |
1 |
1 |
Two-hybrid |
KIN3 |
YAR018C |
Nonessential serine/threonine protein kinase |
physical |
1 |
1 |
1 |
Two-hybrid |
ZIP1 |
YDR285W |
Transverse filament protein of the synaptonemal complex |
physical |
1 |
1 |
1 |
Two-hybrid |
HDA2 |
YDR295C |
Subunit of HDA1 histone deacetylase complex |
physical |
1 |
1 |
1 |
Two-hybrid |
UBA4 |
YHR111W |
E1-like protein that activates Urm1p before urmylation |
physical |
1 |
1 |
1 |
Two-hybrid |
BNR1 |
YIL159W |
Formin |
physical |
1 |
1 |
1 |
Two-hybrid |
KAR2 |
YJL034W |
ATPase involved in protein import into the ER |
physical |
1 |
1 |
1 |
Two-hybrid |
GZF3 |
YJL110C |
GATA zinc finger protein |
physical |
1 |
1 |
1 |
Two-hybrid |
SMY1 |
YKL079W |
Kinesin-like myosin passenger-protein |
physical |
1 |
1 |
1 |
Two-hybrid |
COY1 |
YKL179C |
Golgi membrane protein with similarity to mammalian CASP |
physical |
1 |
1 |
1 |
Two-hybrid |
NDL1 |
YLR254C |
Homolog of nuclear distribution factor NudE |
physical |
1 |
1 |
1 |
Two-hybrid |
IMH1 |
YLR309C |
Protein involved in vesicular transport |
physical |
1 |
1 |
1 |
Two-hybrid |
CDC3 |
YLR314C |
Component of the septin ring that is required for cytokinesis |
physical |
1 |
1 |
1 |
Two-hybrid |
VAC8 |
YEL013W |
Vacuole-specific Myo2p receptor |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
VAC8 |
YEL013W |
Vacuole-specific Myo2p receptor |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
SSB2 |
YNL209W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
1 |
1 |
1 |
Co-purification |
QDR3 |
YBR043C |
Multidrug transporter of the major facilitator superfamily |
physical |
1 |
1 |
1 |
Biochemical Activity |
MTC6 |
YHR151C |
Protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
PLC1 |
YPL268W |
Phospholipase C |
physical |
1 |
1 |
1 |
Biochemical Activity |
YPR084W |
YPR084W |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
NDE2 |
YDL085W |
Mitochondrial external NADH dehydrogenase |
physical |
1 |
1 |
1 |
Biochemical Activity |
PIG1 |
YLR273C |
Putative targeting subunit for type-1 protein phosphatase Glc7p |
physical |
1 |
1 |
1 |
Biochemical Activity |
CEP3 |
YMR168C |
Essential kinetochore protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
CEP3 |
YMR168C |
Essential kinetochore protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
MLO127 |
YJR039W |
Mitochondrial protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
SNU114 |
YKL173W |
GTPase component of U5 snRNP involved in mRNA splicing via spliceosome |
physical |
1 |
1 |
1 |
Biochemical Activity |
SRO7 |
YPR032W |
Effector of Rab GTPase Sec4p |
physical |
1 |
1 |
1 |
Biochemical Activity |
HXT1 |
YHR094C |
Low-affinity glucose transporter of the major facilitator superfamily |
physical |
1 |
1 |
1 |
Biochemical Activity |
PET130 |
YJL023C |
Protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
ATG2 |
YNL242W |
Peripheral membrane protein required for autophagic vesicle formation |
physical |
1 |
1 |
1 |
Biochemical Activity |
GAL10 |
YBR019C |
UDP-glucose-4-epimerase |
physical |
1 |
1 |
1 |
Biochemical Activity |
HSL7 |
YBR133C |
Protein arginine N-methyltransferase |
physical |
1 |
1 |
1 |
Biochemical Activity |
SGV1 |
YPR161C |
Cyclin (Bur2p)-dependent protein kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
YEL1 |
YBL060W |
Guanine nucleotide exchange factor specific for Arf3p |
physical |
1 |
1 |
1 |
Biochemical Activity |
IRC7 |
YFR055W |
Cysteine desulphydrase, enables growth on cysteine as nitrogen source |
physical |
1 |
1 |
1 |
Biochemical Activity |
SNU56 |
YDR240C |
Component of U1 snRNP required for mRNA splicing via spliceosome |
physical |
1 |
1 |
1 |
Biochemical Activity |
UBP12 |
YJL197W |
Ubiquitin-specific protease |
physical |
1 |
1 |
1 |
Biochemical Activity |
UBP12 |
YJL197W |
Ubiquitin-specific protease |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC26 |
YDR238C |
Essential beta-coat protein of the COPI coatomer |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SEC4 |
YFL005W |
Rab family GTPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
VPS1 |
YKR001C |
Dynamin-like GTPase required for vacuolar sorting |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CDC48 |
YDL126C |
AAA ATPase with protein-unfoldase activity |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PIL1 |
YGR086C |
Eisosome core component |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PIL1 |
YGR086C |
Eisosome core component |
genetic |
1 |
1 |
1 |
Negative Genetic |
SAC6 |
YDR129C |
Fimbrin, actin-bundling protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SEC23 |
YPR181C |
GTPase-activating protein, stimulates the GTPase activity of Sar1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SSH4 |
YKL124W |
Specificity factor required for Rsp5p-dependent ubiquitination |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TVP23 |
YDR084C |
Integral membrane protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TVP23 |
YDR084C |
Integral membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS13 |
YLL040C |
Lipid transport protein involved in prospore membrane morphogenesis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SFT2 |
YBL102W |
Tetra-spanning membrane protein found mostly in the late Golgi |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
FKS1 |
YLR342W |
Catalytic subunit of 1,3-beta-D-glucan synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SSO1 |
YPL232W |
Plasma membrane t-SNARE |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CRM1 |
YGR218W |
Nuclear export factor, exportin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PUF2 |
YPR042C |
PUF family mRNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
ISW1 |
YBR245C |
ATPase subunit of imitation-switch (ISWI) class chromatin remodelers |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
MPT5 |
YGL178W |
mRNA-binding protein of the PUF family |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
ATG34 |
YOL083W |
Receptor protein involved in selective autophagy during starvation |
physical |
1 |
1 |
1 |
Biochemical Activity |
PUB1 |
YNL016W |
Poly (A)+ RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PAT1 |
YCR077C |
Deadenylation-dependent mRNA-decapping factor |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
YKT6 |
YKL196C |
Vesicle membrane protein (v-SNARE) with acyltransferase activity |
physical |
1 |
1 |
1 |
Biochemical Activity |
PCL10 |
YGL134W |
Pho85p cyclin |
genetic |
1 |
1 |
1 |
Dosage Rescue |
PCL8 |
YPL219W |
Cyclin |
genetic |
1 |
1 |
1 |
Dosage Rescue |
PTC6 |
YCR079W |
Mitochondrial type 2C protein phosphatase (PP2C) |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
CYC8 |
YBR112C |
General transcriptional co-repressor |
genetic |
1 |
1 |
1 |
Positive Genetic |
OPY1 |
YBR129C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
TPS2 |
YDR074W |
Phosphatase subunit of the trehalose-6-P synthase/phosphatase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
MNN10 |
YDR245W |
Subunit of a Golgi mannosyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
VHS1 |
YDR247W |
Cytoplasmic serine/threonine protein kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
PFK1 |
YGR240C |
Alpha subunit of heterooctameric phosphofructokinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
RCK2 |
YLR248W |
Protein kinase involved in response to oxidative and osmotic stress |
genetic |
1 |
1 |
1 |
Positive Genetic |
FIG4 |
YNL325C |
Phosphatidylinositol 3,5-bisphosphate (PtdIns[3,5]P) phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PFK27 |
YOL136C |
6-phosphofructo-2-kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS30 |
YPL120W |
Subunit of phosphatidylinositol (PtdIns) 3-kinase complexes I and II |
genetic |
1 |
1 |
1 |
Positive Genetic |
CET1 |
YPL228W |
RNA 5'-triphosphatase involved in mRNA 5' capping |
genetic |
1 |
1 |
1 |
Positive Genetic |
BSD2 |
YBR290W |
Heavy metal ion homeostasis protein |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
PNG1 |
YPL096W |
Conserved peptide N-glycanase |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
VAM3 |
YOR106W |
Syntaxin-like vacuolar t-SNARE |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
HDA1 |
YNL021W |
Catalytic subunit of class II HDA1 histone deacetylase complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RPD3 |
YNL330C |
Histone deacetylase, component of both the Rpd3S and Rpd3L complexes |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
HAP5 |
YOR358W |
Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
HAP3 |
YBL021C |
Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
NUP133 |
YKR082W |
Subunit of Nup84p subcomplex of nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SWI5 |
YDR146C |
Transcription factor that recruits Mediator and Swi/Snf complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
KCS1 |
YDR017C |
Inositol hexakisphosphate and inositol heptakisphosphate kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
CLN1 |
YMR199W |
G1 cyclin involved in regulation of the cell cycle |
genetic |
1 |
1 |
1 |
Positive Genetic |
FKH1 |
YIL131C |
Forkhead family transcription factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
HAA1 |
YPR008W |
Transcriptional activator involved in adaptation to weak acid stress |
genetic |
1 |
1 |
1 |
Positive Genetic |
GAT4 |
YIR013C |
Protein containing GATA family zinc finger motifs |
genetic |
1 |
1 |
1 |
Positive Genetic |
YCK3 |
YER123W |
Palmitoylated vacuolar membrane-localized casein kinase I isoform |
genetic |
1 |
1 |
1 |
Positive Genetic |
HSL1 |
YKL101W |
Nim1p-related protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
CUP9 |
YPL177C |
Homeodomain-containing transcriptional repressor |
genetic |
1 |
1 |
1 |
Negative Genetic |
HIR1 |
YBL008W |
Subunit of the HIR complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CTF8 |
YHR191C |
Subunit of a complex with Ctf18p |
genetic |
1 |
1 |
1 |
Negative Genetic |
CBF1 |
YJR060W |
Basic helix-loop-helix (bHLH) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
CTK2 |
YJL006C |
Beta subunit of C-terminal domain kinase I (CTDK-I) |
genetic |
1 |
1 |
1 |
Negative Genetic |
PPH3 |
YDR075W |
Catalytic subunit of protein phosphatase PP4 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS71 |
YML041C |
Nucleosome-binding component of the SWR1 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
DCC1 |
YCL016C |
Subunit of a complex with Ctf8p and Ctf18p |
genetic |
1 |
1 |
1 |
Negative Genetic |
MET18 |
YIL128W |
Component of cytosolic iron-sulfur protein assembly (CIA) machinery |
genetic |
1 |
1 |
1 |
Negative Genetic |
SSO2 |
YMR183C |
Plasma membrane t-SNARE |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
TLG2 |
YOL018C |
Syntaxin-like t-SNARE |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
TRS130 |
YMR218C |
Component of transport protein particle (TRAPP) complex II |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
TRS65 |
YGR166W |
Component of transport protein particle (TRAPP) complex II |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
SNX4 |
YJL036W |
Sorting nexin |
genetic |
1 |
1 |
1 |
Negative Genetic |
ATG20 |
YDL113C |
Sorting nexin family member |
genetic |
1 |
1 |
1 |
Positive Genetic |
ATG23 |
YLR431C |
Peripheral membrane protein required for autophagy and CVT |
genetic |
1 |
1 |
1 |
Positive Genetic |
CCZ1 |
YBR131W |
Subunit of a heterodimeric guanine nucleotide exchange factor (GEF) |
genetic |
1 |
1 |
1 |
Positive Genetic |
TOR1 |
YJR066W |
PIK-related protein kinase and rapamycin target |
genetic |
1 |
1 |
1 |
Positive Genetic |
FTR1 |
YER145C |
High affinity iron permease |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
IRC6 |
YFR043C |
Clathrin coat accessory factor |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
SAH1 |
YER043C |
S-adenosyl-L-homocysteine hydrolase |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
DSF1 |
YEL070W |
Mannitol dehydrogenase |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
FRS2 |
YFL022C |
Alpha subunit of cytoplasmic phenylalanyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
YFL068W |
YFL068W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
LSM5 |
YER146W |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
MGP12 |
YDR286C |
Mitochondrial protein of unknown function |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
GSY1 |
YFR015C |
Glycogen synthase |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
SLX8 |
YER116C |
Subunit of Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
FDC1 |
YDR539W |
Ferulic acid decarboxylase |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
RPL23B |
YER117W |
Ribosomal 60S subunit protein L23B |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
NSE3 |
YDR288W |
Component of the SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
RSM28 |
YDR494W |
Mitochondrial ribosomal protein of the small subunit |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
ERJ5 |
YFR041C |
Type I membrane protein with a J domain |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
HIS1 |
YER055C |
ATP phosphoribosyltransferase |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
SRM1 |
YGL097W |
Nucleotide exchange factor for Gsp1p |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
OCA6 |
YDR067C |
Cytoplasmic protein required for replication of Brome mosaic virus |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
GIN4 |
YDR507C |
Protein kinase involved in bud growth and assembly of the septin ring |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
PRR2 |
YDL214C |
Serine/threonine protein kinase |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
PTK2 |
YJR059W |
Serine/threonine protein kinase |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
SKY1 |
YMR216C |
SR protein kinase (SRPK) |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
SPS1 |
YDR523C |
STE20-family GCKIII protein kinase |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
SSK2 |
YNR031C |
MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
ATG32 |
YIL146C |
Mitochondrial outer membrane protein required to initiate mitophagy |
genetic |
1 |
1 |
1 |
Negative Genetic |
ELO2 |
YCR034W |
Fatty acid elongase, involved in sphingolipid biosynthesis |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
ELO3 |
YLR372W |
Elongase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
NOP2 |
YNL061W |
rRNA m5C methyltransferase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
ORC3 |
YLL004W |
Subunit of the origin recognition complex (ORC) |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
SSC1 |
YJR045C |
Hsp70 family ATPase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
YCG1 |
YDR325W |
Subunit of the condensin complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
CMD1 |
YBR109C |
Calmodulin |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
OKP1 |
YGR179C |
Outer kinetochore protein required for accurate chromosome segregation |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
SEC17 |
YBL050W |
Alpha-SNAP cochaperone |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
RFT1 |
YBL020W |
Membrane protein required for translocation of Man5GlcNac2-PP-Dol |
genetic |
1 |
1 |
1 |
Positive Genetic |
STU1 |
YBL034C |
Microtubule plus-end-tracking non-motor protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
BET4 |
YJL031C |
Alpha subunit of Type II geranylgeranyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
POP3 |
YNL282W |
Subunit of both RNase MRP and nuclear RNase P |
genetic |
1 |
1 |
1 |
Positive Genetic |
SMX3 |
YPR182W |
Core Sm protein Sm F |
genetic |
1 |
1 |
1 |
Positive Genetic |
HAP4 |
YKL109W |
Transcription factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
ECM4 |
YKR076W |
S-glutathionyl-(chloro)hydroquinone reductase (GS-HQR) |
genetic |
1 |
1 |
1 |
Positive Genetic |
ISF1 |
YMR081C |
Serine-rich, hydrophilic protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
YOR292C |
YOR292C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
POP5 |
YAL033W |
Subunit of both RNase MRP and nuclear RNase P |
genetic |
1 |
1 |
1 |
Negative Genetic |
MED8 |
YBR193C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC39 |
YCR093W |
Subunit of the CCR4-NOT1 core complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
DBP10 |
YDL031W |
Putative ATP-dependent RNA helicase of the DEAD-box protein family |
genetic |
1 |
1 |
1 |
Negative Genetic |
STN1 |
YDR082W |
Telomere end-binding and capping protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
TAF12 |
YDR145W |
Subunit (61/68 kDa) of TFIID and SAGA complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
CAB5 |
YDR196C |
Subunit of the CoA-Synthesizing Protein Complex (CoA-SPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
ESF1 |
YDR365C |
Nucleolar protein involved in pre-rRNA processing |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPB4 |
YFL002C |
Putative ATP-dependent RNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
CFD1 |
YIL003W |
Highly conserved iron-sulfur cluster binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
CYR1 |
YJL005W |
Adenylate cyclase |
genetic |
1 |
1 |
1 |
Negative Genetic |
TIM54 |
YJL054W |
Component of the mitochondrial TIM22 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PAM16 |
YJL104W |
Subunit of the import motor (PAM complex) |
genetic |
1 |
1 |
1 |
Negative Genetic |
URB2 |
YJR041C |
Protein required for normal metabolism of the rRNA primary transcript |
genetic |
1 |
1 |
1 |
Negative Genetic |
MAK11 |
YKL021C |
Protein involved in an early step of 60S ribosomal subunit biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
TOR2 |
YKL203C |
PIK-related protein kinase and rapamycin target |
genetic |
1 |
1 |
1 |
Negative Genetic |
UBA1 |
YKL210W |
Ubiquitin activating enzyme (E1) |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL15A |
YLR029C |
Ribosomal 60S subunit protein L15A |
genetic |
1 |
1 |
1 |
Negative Genetic |
STU2 |
YLR045C |
Microtubule polymerase of the XMAP215/Dis1 family |
genetic |
1 |
1 |
1 |
Negative Genetic |
CFT2 |
YLR115W |
Subunit of the mRNA cleavage and polyadenlylation factor (CPF) |
genetic |
1 |
1 |
1 |
Negative Genetic |
STT4 |
YLR305C |
Phosphatidylinositol-4-kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RSE1 |
YML049C |
Protein involved in pre-mRNA splicing |
genetic |
1 |
1 |
1 |
Negative Genetic |
PDS5 |
YMR076C |
Cohesion maintenance factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
CTF13 |
YMR094W |
Subunit of the CBF3 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERG8 |
YMR220W |
Phosphomevalonate kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
CUS1 |
YMR240C |
Protein required for assembly of U2 snRNP into the spliceosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
POL1 |
YNL102W |
Catalytic subunit of the DNA polymerase I alpha-primase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
DBP2 |
YNL112W |
ATP-dependent RNA helicase of the DEAD-box protein family |
genetic |
1 |
1 |
1 |
Negative Genetic |
DCP1 |
YOL149W |
Subunit of the Dcp1p-Dcp2p decapping enzyme complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
UFE1 |
YOR075W |
t-SNARE protein required for retrograde vesicular traffic |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPN8 |
YOR261C |
Essential non-ATPase regulatory subunit of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
NOG1 |
YPL093W |
Putative GTPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
TIF6 |
YPR016C |
Constituent of 66S pre-ribosomal particles |
genetic |
1 |
1 |
1 |
Negative Genetic |
RDS3 |
YPR094W |
Component of the SF3b subcomplex of the U2 snRNP |
genetic |
1 |
1 |
1 |
Negative Genetic |
YTH1 |
YPR107C |
Essential RNA-binding component of cleavage and polyadenylation factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
PZF1 |
YPR186C |
Transcription factor IIIA (TFIIIA) |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC24 |
YAL041W |
Guanine nucleotide exchange factor (GEF) for Cdc42p |
genetic |
1 |
1 |
1 |
Negative Genetic |
TIM22 |
YDL217C |
Essential core component of mitochondrial TIM22 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
BOS1 |
YLR078C |
v-SNARE (vesicle specific SNAP receptor) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC22 |
YLR268W |
R-SNARE protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERP2 |
YAL007C |
Member of the p24 family involved in ER to Golgi transport |
genetic |
1 |
1 |
1 |
Negative Genetic |
YAL064W |
YAL064W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
SHP1 |
YBL058W |
UBX domain-containing substrate adaptor for Cdc48p |
genetic |
1 |
1 |
1 |
Negative Genetic |
SSA3 |
YBL075C |
ATPase involved in protein folding and the response to stress |
genetic |
1 |
1 |
1 |
Negative Genetic |
ECM21 |
YBL101C |
Alpha-arrestin, ubiquitin ligase adaptor for Rsp5p |
genetic |
1 |
1 |
1 |
Negative Genetic |
PEX32 |
YBR168W |
Peroxisomal integral membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
SSE2 |
YBR169C |
Member of Hsp110 subclass of the heat shock protein 70 (HSP70) family |
genetic |
1 |
1 |
1 |
Negative Genetic |
COS111 |
YBR203W |
Protein required for antifungal drug ciclopirox olamine resistance |
genetic |
1 |
1 |
1 |
Negative Genetic |
UBX7 |
YBR273C |
UBX (ubiquitin regulatory X) domain-containing protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRPL32 |
YCR003W |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
NPP1 |
YCR026C |
Nucleotide pyrophosphatase/phosphodiesterase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RIM1 |
YCR028C-A |
ssDNA-binding protein essential for mitochondrial genome maintenance |
genetic |
1 |
1 |
1 |
Negative Genetic |
CSM1 |
YCR086W |
Nucleolar protein that mediates homolog segregation during meiosis I |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC50 |
YCR094W |
Endosomal protein that interacts with phospholipid flippase Drs2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERP3 |
YDL018C |
Protein with similarity to Emp24p and Erv25p |
genetic |
1 |
1 |
1 |
Negative Genetic |
YDL085C-A |
YDL085C-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
NUP84 |
YDL116W |
Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
EXP1 |
YDL121C |
A cargo receptor protein for Pma1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
UBP1 |
YDL122W |
Ubiquitin-specific protease |
genetic |
1 |
1 |
1 |
Negative Genetic |
SRF1 |
YDL133W |
Regulator of phospholipase D (Spo14p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
DTD1 |
YDL219W |
D-Tyr-tRNA(Tyr) deacylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
OST4 |
YDL232W |
Subunit of the oligosaccharyltransferase complex of the ER lumen |
genetic |
1 |
1 |
1 |
Negative Genetic |
DAS2 |
YDR020C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
RTR2 |
YDR066C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
FMP16 |
YDR070C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
DNF2 |
YDR093W |
Aminophospholipid translocase (flippase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
BTT1 |
YDR252W |
Heterotrimeric nascent polypeptide-associated complex beta3 subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
PAL1 |
YDR348C |
Protein of unknown function thought to be involved in endocytosis |
genetic |
1 |
1 |
1 |
Negative Genetic |
RMT2 |
YDR465C |
Arginine N5 methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
YAT2 |
YER024W |
Carnitine acetyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ICP55 |
YER078C |
Mitochondrial aminopeptidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SBH1 |
YER087C-B |
Beta subunit of Sec61p ER translocation complex (Sec61p-Sss1p-Sbh1p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
GLE2 |
YER107C |
RNA export factor associated with the nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
RTR1 |
YER139C |
Dual specificity protein phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SLO1 |
YER180C-A |
Protein interacting with Arl3p |
genetic |
1 |
1 |
1 |
Negative Genetic |
GYP8 |
YFL027C |
GTPase-activating protein for yeast Rab family members |
genetic |
1 |
1 |
1 |
Negative Genetic |
YFR006W |
YFR006W |
Putative X-Pro aminopeptidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
GCN20 |
YFR009W |
Positive regulator of the Gcn2p kinase activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
YGL159W |
YGL159W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERV46 |
YAL042W |
Protein localized to COPII-coated vesicles |
genetic |
1 |
1 |
1 |
Negative Genetic |
DBF2 |
YGR092W |
Ser/Thr kinase involved in transcription and stress response |
genetic |
1 |
1 |
1 |
Negative Genetic |
PIR5 |
YJL160C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
SIW14 |
YNL032W |
Inositol phosphatase involved in inositol pyrophosphate metabolism |
genetic |
1 |
1 |
1 |
Negative Genetic |
ATP23 |
YNR020C |
Putative metalloprotease of the mitochondrial inner membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
SIN3 |
YOL004W |
Component of both the Rpd3S and Rpd3L histone deacetylase complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
PMA2 |
YPL036W |
Plasma membrane H+-ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPE3 |
YPR069C |
Spermidine synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
FMP48 |
YGR052W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
CLB1 |
YGR108W |
B-type cyclin involved in cell cycle progression |
genetic |
1 |
1 |
1 |
Negative Genetic |
YGR153W |
YGR153W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
CIR1 |
YGR207C |
Mitochondrial protein that interacts with frataxin (Yfh1p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
CPD1 |
YGR247W |
Cyclic nucleotide phosphodiesterase |
genetic |
1 |
1 |
1 |
Negative Genetic |
YHL015W-A |
YHL015W-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
MCO14 |
YHL018W |
Putative 4a-hydroxytetrahydrobiopterin dehydratase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SMF2 |
YHR050W |
Divalent metal ion transporter involved in manganese homeostasis |
genetic |
1 |
1 |
1 |
Negative Genetic |
NMD2 |
YHR077C |
Protein involved in the nonsense-mediated mRNA decay (NMD) pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
PEX18 |
YHR160C |
Peroxin |
genetic |
1 |
1 |
1 |
Negative Genetic |
SNL1 |
YIL016W |
Ribosome-associated protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
RGI2 |
YIL057C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
AYR1 |
YIL124W |
Bifunctional triacylglycerol lipase and 1-acyl DHAP reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MGA2 |
YIR033W |
ER membrane protein involved in regulation of OLE1 transcription |
genetic |
1 |
1 |
1 |
Negative Genetic |
NRE1 |
YIR035C |
Putative cytoplasmic short-chain dehydrogenase/reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
GTT1 |
YIR038C |
ER associated glutathione S-transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
IRC8 |
YJL051W |
Bud tip localized protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YJL107C |
YJL107C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
MTC1 |
YJL123C |
Protein of unknown function that may interact with ribosomes |
genetic |
1 |
1 |
1 |
Negative Genetic |
PAU1 |
YJL223C |
Member of the seripauperin multigene family |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPC1 |
YJR010C-A |
Subunit of the signal peptidase complex (SPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
YJR056C |
YJR056C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL43B |
YJR094W-A |
Ribosomal 60S subunit protein L43B |
genetic |
1 |
1 |
1 |
Negative Genetic |
NNK1 |
YKL171W |
Protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
LOS1 |
YKL205W |
Nuclear pore protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
MIC60 |
YKR016W |
Component of the MICOS complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
TVP38 |
YKR088C |
Integral membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
MMM1 |
YLL006W |
ER integral membrane protein, ERMES complex subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
YPS1 |
YLR120C |
Aspartic protease |
genetic |
1 |
1 |
1 |
Negative Genetic |
STM1 |
YLR150W |
Protein required for optimal translation under nutrient stress |
genetic |
1 |
1 |
1 |
Negative Genetic |
YLR154C-G |
YLR154C-G |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
PEX13 |
YLR191W |
Peroxisomal importomer complex component |
genetic |
1 |
1 |
1 |
Negative Genetic |
ATP14 |
YLR295C |
Subunit h of the F0 sector of mitochondrial F1F0 ATP synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
UBC12 |
YLR306W |
Enzyme that mediates the conjugation of Rub1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
ATG39 |
YLR312C |
Transmembrane receptor with a role in nucleophagy |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS25B |
YLR333C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
YLR363W-A |
YLR363W-A |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YLR419W |
YLR419W |
Putative helicase with limited sequence similarity to human Rb protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
PAU4 |
YLR461W |
Member of the seripauperin multigene family |
genetic |
1 |
1 |
1 |
Negative Genetic |
CUE4 |
YML101C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YMR206W |
YMR206W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
SCJ1 |
YMR214W |
One of several homologs of bacterial chaperone DnaJ |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS10B |
YMR230W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
PET111 |
YMR257C |
Mitochondrial translational activator specific for the COX2 mRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS7B |
YNL096C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
IST1 |
YNL265C |
Protein with positive role in the multivesicular body sorting pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
CAF120 |
YNL278W |
Part of the CCR4-NOT transcriptional regulatory complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERG24 |
YNL280C |
C-14 sterol reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
LRO1 |
YNR008W |
Acyltransferase that converts diacylglycerol to triacylglycerol (TGA) |
genetic |
1 |
1 |
1 |
Negative Genetic |
HUB1 |
YNR032C-A |
Ubiquitin-like protein modifier |
genetic |
1 |
1 |
1 |
Negative Genetic |
YNR064C |
YNR064C |
Epoxide hydrolase |
genetic |
1 |
1 |
1 |
Negative Genetic |
TOP1 |
YOL006C |
Topoisomerase I |
genetic |
1 |
1 |
1 |
Negative Genetic |
HTZ1 |
YOL012C |
Histone variant H2AZ |
genetic |
1 |
1 |
1 |
Negative Genetic |
MCH4 |
YOL119C |
Protein with similarity to mammalian monocarboxylate permeases |
genetic |
1 |
1 |
1 |
Negative Genetic |
YOL155W-A |
YOL155W-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
PAU20 |
YOL161C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
CRC1 |
YOR100C |
Mitochondrial inner membrane carnitine transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
GET4 |
YOR164C |
Protein involved in inserting tail-anchored proteins into ER membranes |
genetic |
1 |
1 |
1 |
Negative Genetic |
RCN2 |
YOR220W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
MUM3 |
YOR298W |
Protein of unknown function involved in outer spore wall organization |
genetic |
1 |
1 |
1 |
Negative Genetic |
CTF19 |
YPL018W |
Outer kinetochore protein, needed for accurate chromosome segregation |
genetic |
1 |
1 |
1 |
Negative Genetic |
MET31 |
YPL038W |
Zinc-finger DNA-binding transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
SSE1 |
YPL106C |
ATPase component of heat shock protein Hsp90 chaperone complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ODC1 |
YPL134C |
Mitochondrial inner membrane transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRX4 |
YPL168W |
Protein that associates with mitochondrial ribosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
ATG41 |
YPL250C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
PAU22 |
YPL282C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
VMA13 |
YPR036W |
Subunit H of the V1 peripheral membrane domain of V-ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
TDA6 |
YPR157W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC9 |
YDL164C |
DNA ligase I found in nucleus and mitochondria |
genetic |
1 |
1 |
1 |
Positive Genetic |
SAS3 |
YBL052C |
Histone acetyltransferase catalytic subunit of NuA3 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
FUM1 |
YPL262W |
Fumarase |
genetic |
1 |
1 |
1 |
Negative Genetic |
TFS1 |
YLR178C |
Inhibitor of carboxypeptidase Y (Prc1p), and Ras GAP (Ira2p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
ATG3 |
YNR007C |
E2-like enzyme |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
ATG12 |
YBR217W |
Ubiquitin-like modifier involved in autophagy and the Cvt pathway |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
ATG16 |
YMR159C |
Conserved protein involved in autophagy |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
PMA1 |
YGL008C |
Plasma membrane P2-type H+-ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
GCN4 |
YEL009C |
bZIP transcriptional activator of amino acid biosynthetic genes |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
HRQ1 |
YDR291W |
3'-5' DNA helicase of the conserved RecQ family |
genetic |
1 |
1 |
1 |
Negative Genetic |
SGS1 |
YMR190C |
RecQ family nucleolar DNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SAC1 |
YKL212W |
Phosphatidylinositol phosphate phosphatase |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
EDE1 |
YBL047C |
Scaffold protein involved in the formation of early endocytic sites |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
ALY2 |
YJL084C |
Alpha arrestin, Ub-ligase adaptor for Rsp5p |
physical |
1 |
1 |
1 |
Biochemical Activity |
AIM3 |
YBR108W |
Protein that inhibits barbed-end actin filament elongation |
physical |
1 |
1 |
1 |
Biochemical Activity |
ASK10 |
YGR097W |
Regulator of the Fps1p glycerol channel |
genetic |
1 |
1 |
1 |
Negative Genetic |
APC5 |
YOR249C |
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
APN1 |
YKL114C |
Major apurinic/apyrimidinic endonuclease |
physical |
1 |
1 |
1 |
Biochemical Activity |
ALY1 |
YKR021W |
Alpha arrestin, substrate of calcineurin |
physical |
1 |
1 |
1 |
Biochemical Activity |
APM2 |
YHL019C |
Protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
ASF2 |
YDL197C |
Anti-silencing protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
ANT1 |
YPR128C |
Peroxisomal adenine nucleotide transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
AQY3 |
YFL054C |
Putative channel-like protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
ACL4 |
YDR161W |
Specific assembly chaperone for ribosomal protein Rpl4a/Rpl4b |
physical |
1 |
1 |
1 |
Biochemical Activity |
ABP140 |
YOR239W |
AdoMet-dependent tRNA methyltransferase and actin binding protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
ALR2 |
YFL050C |
Probable Mg(2+) transporter |
physical |
1 |
1 |
1 |
Biochemical Activity |
AST2 |
YER101C |
Lipid raft associated protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
ALG14 |
YBR070C |
Component of UDP-GlcNAc transferase |
physical |
1 |
1 |
1 |
Biochemical Activity |
ALG9 |
YNL219C |
Mannosyltransferase, involved in N-linked glycosylation |
genetic |
1 |
1 |
1 |
Negative Genetic |
ALG8 |
YOR067C |
Glucosyl transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |