RRP8 |
YDR083W |
Nucleolar S-adenosylmethionine-dependent rRNA methyltransferase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
AAH1 |
YNL141W |
Adenine deaminase (adenine aminohydrolase) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SST2 |
YLR452C |
GTPase-activating protein for Gpa1p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
STB5 |
YHR178W |
Transcription factor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
FAA1 |
YOR317W |
Long chain fatty acyl-CoA synthetase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
BTS1 |
YPL069C |
Geranylgeranyl diphosphate synthase (GGPPS) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RPS10A |
YOR293W |
Protein component of the small (40S) ribosomal subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ESA1 |
YOR244W |
Catalytic subunit of the histone acetyltransferase complex (NuA4) |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
SSP1 |
YHR184W |
Protein involved in the control of meiotic nuclear division |
physical |
2 |
1 |
1 |
Affinity Capture-Western, Affinity Capture-Western |
YAF9 |
YNL107W |
Subunit of NuA4 histone H4 acetyltransferase and SWR1 complexes |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
SFP1 |
YLR403W |
Regulates transcription of ribosomal protein and biogenesis genes |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
NDT80 |
YHR124W |
Meiosis-specific transcription factor |
regulation |
1 |
1 |
1 |
northern blot evidence |
CDC15 |
YAR019C |
Hippo-like kinase of the Mitotic Exit Network |
regulation |
1 |
1 |
1 |
protein kinase assay evidence |
CDC40 |
YDR364C |
Pre-mRNA splicing factor |
physical |
1 |
1 |
1 |
Reconstituted Complex |
DSN1 |
YIR010W |
Essential component of the outer kinetochore MIND complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPO21 |
YDL140C |
RNA polymerase II largest subunit B220 |
genetic |
1 |
1 |
1 |
Negative Genetic |
CKB1 |
YGL019W |
Beta regulatory subunit of casein kinase 2 (CK2) |
physical |
1 |
1 |
1 |
Reconstituted Complex |
SDS22 |
YKL193C |
Regulatory subunit of the type 1 protein phosphatase (PP1) Glc7p |
physical |
1 |
1 |
1 |
Reconstituted Complex |
GUS1 |
YGL245W |
Glutamyl-tRNA synthetase (GluRS) |
physical |
1 |
1 |
1 |
Reconstituted Complex |
BMH1 |
YER177W |
14-3-3 protein, major isoform |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
BMH1 |
YER177W |
14-3-3 protein, major isoform |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
RPN8 |
YOR261C |
Essential non-ATPase regulatory subunit of the 26S proteasome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPT6 |
YGL048C |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
NAM7 |
YMR080C |
ATP-dependent RNA helicase of the SFI superfamily |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
ARP2 |
YDL029W |
Essential component of the Arp2/3 complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BMH2 |
YDR099W |
14-3-3 protein, minor isoform |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
BMH2 |
YDR099W |
14-3-3 protein, minor isoform |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
CDC28 |
YBR160W |
Cyclin-dependent kinase (CDK) catalytic subunit |
genetic |
1 |
1 |
1 |
Dosage Lethality |
CDC23 |
YHR166C |
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
ISW1 |
YBR245C |
ATPase subunit of imitation-switch (ISWI) class chromatin remodelers |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
DIB1 |
YPR082C |
17-kDa component of the U4/U6aU5 tri-snRNP |
physical |
1 |
1 |
1 |
Reconstituted Complex |
AHA1 |
YDR214W |
Co-chaperone that binds Hsp82p and activates its ATPase activity |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HMO1 |
YDR174W |
Chromatin associated high mobility group (HMG) family member |
genetic |
1 |
1 |
1 |
Negative Genetic |
PPH22 |
YDL188C |
Catalytic subunit of protein phosphatase 2A, PP2A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DAM1 |
YGR113W |
Essential subunit of the Dam1 complex (aka DASH complex) |
genetic |
1 |
1 |
1 |
Negative Genetic |
CTI6 |
YPL181W |
Component of the Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
PPH21 |
YDL134C |
Catalytic subunit of protein phosphatase 2A, PP2A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SIR2 |
YDL042C |
Conserved NAD+ dependent histone deacetylase of the Sirtuin family |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
HFI1 |
YPL254W |
Adaptor protein required for structural integrity of the SAGA complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SGF73 |
YGL066W |
Subunit of DUBm module of SAGA and SLIK |
physical |
1 |
1 |
1 |
Biochemical Activity |
SGV1 |
YPR161C |
Cyclin (Bur2p)-dependent protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
CCT6 |
YDR188W |
Subunit of the cytosolic chaperonin Cct ring complex |
physical |
1 |
1 |
1 |
Reconstituted Complex |
CCT6 |
YDR188W |
Subunit of the cytosolic chaperonin Cct ring complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
NEW1 |
YPL226W |
Translation termination and ribosome biogenesis factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
HEK2 |
YBL032W |
RNA binding protein involved in asymmetric localization of ASH1 mRNA |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
ABP1 |
YCR088W |
Actin-binding protein of the cortical actin cytoskeleton |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PHO84 |
YML123C |
High-affinity inorganic phosphate (Pi) transporter |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ATP3 |
YBR039W |
Gamma subunit of the F1 sector of mitochondrial F1F0 ATP synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PYC1 |
YGL062W |
Pyruvate carboxylase isoform |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
IDH1 |
YNL037C |
Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PLN1 |
YKR046C |
Perilipin, involved in formation and stability of lipid droplets |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YHR033W |
YHR033W |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
VMA8 |
YEL051W |
Subunit D of the V1 peripheral membrane domain of V-ATPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
VPS74 |
YDR372C |
Golgi PI4K effector, PtdIns4P sensor, and retention receptor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TFC3 |
YAL001C |
Subunit of RNA polymerase III transcription initiation factor complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TMA16 |
YOR252W |
Protein of unknown function that associates with ribosomes |
physical |
1 |
1 |
1 |
Biochemical Activity |
SSE1 |
YPL106C |
ATPase component of heat shock protein Hsp90 chaperone complex |
physical |
1 |
1 |
1 |
Reconstituted Complex |
UBC6 |
YER100W |
Ubiquitin-conjugating enzyme involved in ERAD |
physical |
1 |
1 |
1 |
Reconstituted Complex |
UBP10 |
YNL186W |
Ubiquitin-specific protease, deubiquitinates Ub-protein moieties |
physical |
1 |
1 |
1 |
Reconstituted Complex |
YBL036C |
YBL036C |
Putative non-specific single-domain racemase |
physical |
1 |
1 |
1 |
Reconstituted Complex |
YMR196W |
YMR196W |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Reconstituted Complex |
YAK1 |
YJL141C |
Serine-threonine protein kinase |
physical |
1 |
1 |
1 |
Reconstituted Complex |
YPK1 |
YKL126W |
S/T protein kinase |
physical |
1 |
1 |
1 |
Reconstituted Complex |
SUS1 |
YBR111W-A |
Global transcriptional regulator, component of SAGA, TREX-2 complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TAF5 |
YBR198C |
Subunit (90 kDa) of TFIID and SAGA complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
STE20 |
YHL007C |
Cdc42p-activated signal transducing kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
YOR289W |
YOR289W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
TIM22 |
YDL217C |
Essential core component of mitochondrial TIM22 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
TAF12 |
YDR145W |
Subunit (61/68 kDa) of TFIID and SAGA complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
TEL2 |
YGR099W |
Subunit of the ASTRA complex, involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Negative Genetic |
STP2 |
YHR006W |
Transcription factor |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
CPR6 |
YLR216C |
Peptidyl-prolyl cis-trans isomerase (cyclophilin) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PRB1 |
YEL060C |
Vacuolar proteinase B (yscB) with H3 N-terminal endopeptidase activity |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SDH2 |
YLL041C |
Iron-sulfur protein subunit of succinate dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NMD5 |
YJR132W |
Karyopherin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DPS1 |
YLL018C |
Aspartyl-tRNA synthetase, primarily cytoplasmic |
physical |
1 |
1 |
1 |
Reconstituted Complex |
MPC54 |
YOR177C |
Component of the meiotic outer plaque |
physical |
1 |
1 |
1 |
Reconstituted Complex |
PMA1 |
YGL008C |
Plasma membrane P2-type H+-ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
DUN1 |
YDL101C |
Cell-cycle checkpoint S/T protein kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
RNA1 |
YMR235C |
GTPase activating protein (GAP) for Gsp1p |
physical |
1 |
1 |
1 |
Reconstituted Complex |
RVS167 |
YDR388W |
Calmodulin-binding actin-associated protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CDC15 |
YAR019C |
Hippo-like kinase of the Mitotic Exit Network |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
CDC15 |
YAR019C |
Hippo-like kinase of the Mitotic Exit Network |
genetic |
1 |
1 |
1 |
Negative Genetic |
HHO1 |
YPL127C |
Histone H1, linker histone with roles in meiosis and sporulation |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
SKA1 |
YKL023W |
SKI complex-associated protein |
physical |
1 |
1 |
1 |
Reconstituted Complex |
ATG1 |
YGL180W |
Protein serine/threonine kinase |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
MOB2 |
YFL034C-B |
Activator of Cbk1p kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
IME1 |
YJR094C |
Master regulator of meiosis that is active only during meiotic events |
genetic |
1 |
1 |
1 |
Positive Genetic |
RBD2 |
YPL246C |
Possible rhomboid protease |
physical |
1 |
1 |
1 |
Biochemical Activity |
SMC5 |
YOL034W |
Subunit of the SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC27 |
YBL084C |
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
physical |
1 |
1 |
1 |
Two-hybrid |
RPL22A |
YLR061W |
Ribosomal 60S subunit protein L22A |
genetic |
1 |
1 |
1 |
Negative Genetic |
CSE4 |
YKL049C |
Centromeric histone H3-like protein |
physical |
1 |
1 |
1 |
Two-hybrid |
APN1 |
YKL114C |
Major apurinic/apyrimidinic endonuclease |
physical |
1 |
1 |
1 |
Reconstituted Complex |
AMA1 |
YGR225W |
Activator of meiotic anaphase promoting complex (APC/C) |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
PUP1 |
YOR157C |
Beta 2 subunit of the 20S proteasome |
physical |
1 |
1 |
1 |
Two-hybrid |
DPH1 |
YIL103W |
Protein required for synthesis of diphthamide |
physical |
1 |
1 |
1 |
Biochemical Activity |
COQ1 |
YBR003W |
Hexaprenyl pyrophosphate synthetase |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
GPR1 |
YDL035C |
Plasma membrane G protein coupled receptor (GPCR) |
genetic |
1 |
1 |
1 |
Positive Genetic |
CQD1 |
YPL109C |
UbiB family mitochondrial protein |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
DOM34 |
YNL001W |
Protein that facilitates ribosomal subunit dissociation |
physical |
1 |
1 |
1 |
Reconstituted Complex |
ARO8 |
YGL202W |
Aromatic aminotransferase I |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BCH2 |
YKR027W |
Member of the ChAPs (Chs5p-Arf1p-binding proteins) family |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
PHR1 |
YOR386W |
DNA photolyase involved in photoreactivation |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
SPO75 |
YLL005C |
Meiosis-specific protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CYK3 |
YDL117W |
SH3-domain protein located in the bud neck and cytokinetic actin ring |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
RDS2 |
YPL133C |
Transcription factor involved in regulating gluconeogenesis |
physical |
1 |
1 |
1 |
Reconstituted Complex |
CYC7 |
YEL039C |
Cytochrome c isoform 2, expressed under hypoxic conditions |
physical |
1 |
1 |
1 |
Reconstituted Complex |
BNA2 |
YJR078W |
Tryptophan 2,3-dioxygenase or indoleamine 2,3-dioxygenase |
physical |
1 |
1 |
1 |
Biochemical Activity |
LIP1 |
YMR298W |
Ceramide synthase subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARF3 |
YOR094W |
Glucose-repressible ADP-ribosylation factor |
physical |
1 |
1 |
1 |
Reconstituted Complex |
KNH1 |
YDL049C |
Protein with similarity to Kre9p |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
MET22 |
YOL064C |
Bisphosphate-3'-nucleotidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPO77 |
YLR341W |
Meiosis-specific protein of unknown function |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |