Standard name Systematic name Name description Description
SDS22 YKL193C Regulatory subunit of the type 1 protein phosphatase (PP1) Glc7p Regulatory subunit of the type 1 protein phosphatase (PP1) Glc7p; whether it functions as a positive or negative regulator of Glc7p is controversial; involved in the regulation of Glc7p nuclear localization and function
Visualize the interactome of SDS22
Links to external databases:
SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.963 0.959 0.987

GFP localization & abundance

GFP localization GFP abundance
cytoplasm, nucleus 3870

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
SDS22 0 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
GLC7 YER133W Type 1 S/T protein phosphatase (PP1) catalytic subunit physical 19 3 14 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Affinity Capture-MS, Affinity Capture-Western
IPL1 YPL209C Aurora kinase of chromosomal passenger complex genetic 7 2 7 Synthetic Rescue, Dosage Rescue, Dosage Rescue, Synthetic Rescue, Synthetic Rescue, Dosage Rescue, Synthetic Rescue
GLC7 YER133W Type 1 S/T protein phosphatase (PP1) catalytic subunit genetic 6 3 5 Dosage Rescue, Dosage Rescue, Dosage Rescue, Dosage Rescue, Synthetic Lethality, Negative Genetic
YPI1 YFR003C Regulatory subunit of the type I protein phosphatase (PP1) Glc7p physical 5 4 4 Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, Affinity Capture-Western, PCA
PPZ1 YML016C Serine/threonine protein phosphatase Z, isoform of Ppz2p physical 4 1 4 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
YDJ1 YNL064C Type I HSP40 co-chaperone genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
STI1 YOR027W Evolutionarily-conserved Hsp90 cochaperone genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
SHP1 YBL058W UBX domain-containing substrate adaptor for Cdc48p physical 3 2 2 Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS
HDA1 YNL021W Catalytic subunit of class II HDA1 histone deacetylase complex genetic 3 2 2 Dosage Lethality, Dosage Lethality, Negative Genetic
PPZ2 YDR436W Serine/threonine protein phosphatase Z, isoform of Ppz1p physical 3 1 2 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
BUB3 YOR026W Kinetochore checkpoint WD40 repeat protein physical 3 2 1 Reconstituted Complex, Reconstituted Complex, Two-hybrid
SNF4 YGL115W Activating gamma subunit of the AMP-activated Snf1p kinase complex physical 2 2 2 Affinity Capture-MS, Reconstituted Complex
YPT6 YLR262C Rab family GTPase genetic 2 2 2 Positive Genetic, Negative Genetic
RVB1 YDR190C ATP-dependent DNA helicase, also known as pontin physical 2 2 2 Affinity Capture-MS, Reconstituted Complex
NOP6 YDL213C rRNA-binding protein required for 40S ribosomal subunit biogenesis physical 2 2 2 Affinity Capture-MS, Reconstituted Complex
KOG1 YHR186C Subunit of TORC1 physical 2 2 2 Affinity Capture-MS, Reconstituted Complex
STU1 YBL034C Microtubule plus-end-tracking non-motor protein genetic 2 1 2 Negative Genetic, Negative Genetic
SST2 YLR452C GTPase-activating protein for Gpa1p genetic 2 1 2 Negative Genetic, Negative Genetic
RPP2B YDR382W Ribosomal protein P2 beta genetic 2 1 2 Negative Genetic, Negative Genetic
PPQ1 YPL179W Protein phosphatase that regulates the mating response physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
HAL5 YJL165C Snf1p-related nutrient-responsive protein kinase genetic 2 1 2 Negative Genetic, Negative Genetic
HUR1 YGL168W Protein with a role in DNA repair genetic 2 1 2 Negative Genetic, Negative Genetic
LDB18 YLL049W Component of the dynactin complex genetic 2 1 2 Negative Genetic, Negative Genetic
SCS7 YMR272C Sphingolipid alpha-hydroxylase genetic 2 1 2 Negative Genetic, Negative Genetic
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes genetic 2 1 1 Dosage Lethality, Dosage Lethality
MED6 YHR058C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CDC73 YLR418C Component of the Paf1p complex genetic 1 1 1 Synthetic Lethality
LEO1 YOR123C Component of the Paf1 complex genetic 1 1 1 Negative Genetic
CKB1 YGL019W Beta regulatory subunit of casein kinase 2 (CK2) genetic 1 1 1 Positive Genetic
YPI1 YFR003C Regulatory subunit of the type I protein phosphatase (PP1) Glc7p genetic 1 1 1 Negative Genetic
YGR130C YGR130C Component of the eisosome with unknown function physical 1 1 1 Affinity Capture-MS
SNF1 YDR477W AMP-activated S/T protein kinase physical 1 1 1 Affinity Capture-MS
STU1 YBL034C Microtubule plus-end-tracking non-motor protein physical 1 1 1 Affinity Capture-MS
VPS8 YAL002W Membrane-binding component of the CORVET complex physical 1 1 1 Affinity Capture-MS
TPK1 YJL164C cAMP-dependent protein kinase catalytic subunit physical 1 1 1 Biochemical Activity
SIC1 YLR079W Cyclin-dependent kinase inhibitor (CKI) physical 1 1 1 PCA
SEN1 YLR430W ATP-dependent 5' to 3' RNA/DNA and DNA helicase physical 1 1 1 Affinity Capture-MS
SPS1 YDR523C STE20-family GCKIII protein kinase physical 1 1 1 Reconstituted Complex
VHS1 YDR247W Cytoplasmic serine/threonine protein kinase physical 1 1 1 Reconstituted Complex
SPT21 YMR179W Protein with a role in transcriptional silencing physical 1 1 1 Affinity Capture-MS
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p physical 1 1 1 Affinity Capture-MS
SSB1 YDL229W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Affinity Capture-MS
SHP1 YBL058W UBX domain-containing substrate adaptor for Cdc48p genetic 1 1 1 Synthetic Lethality
SET1 YHR119W Histone methyltransferase, subunit of the COMPASS (Set1C) complex genetic 1 1 1 Synthetic Lethality
SNT1 YCR033W Set3C histone deacetylase scaffold genetic 1 1 1 Negative Genetic
ZRT1 YGL255W High-affinity zinc transporter of the plasma membrane genetic 1 1 1 Negative Genetic
VAM7 YGL212W Vacuolar SNARE protein genetic 1 1 1 Negative Genetic
VPS29 YHR012W Subunit of the membrane-associated retromer complex genetic 1 1 1 Negative Genetic
YHR140W YHR140W Endoplasmic reticulum protein genetic 1 1 1 Negative Genetic
STB5 YHR178W Transcription factor genetic 1 1 1 Negative Genetic
SMA2 YML066C Meiosis-specific prospore membrane protein genetic 1 1 1 Negative Genetic
YHM2 YMR241W Citrate and oxoglutarate carrier protein genetic 1 1 1 Negative Genetic
SMM1 YNR015W Dihydrouridine synthase genetic 1 1 1 Positive Genetic
VAM3 YOR106W Syntaxin-like vacuolar t-SNARE genetic 1 1 1 Negative Genetic
THP3 YPR045C Protein that may have a role in transcription elongation genetic 1 1 1 Negative Genetic
YNG2 YHR090C Subunit of NuA4, an essential histone acetyltransferase complex genetic 1 1 1 Dosage Growth Defect
SMC3 YJL074C Subunit of the multiprotein cohesin complex genetic 1 1 1 Synthetic Lethality
TTI2 YJR136C Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Positive Genetic
SLT2 YHR030C Serine/threonine MAP kinase genetic 1 1 1 Dosage Growth Defect
SRP101 YDR292C Signal recognition particle (SRP) receptor alpha subunit genetic 1 1 1 Negative Genetic
SUP35 YDR172W Translation termination factor eRF3 genetic 1 1 1 Negative Genetic
SPC105 YGL093W Subunit of a kinetochore-microtubule binding complex genetic 1 1 1 Negative Genetic
TAD3 YLR316C Subunit of tRNA-specific adenosine-34 deaminase genetic 1 1 1 Negative Genetic
SPC24 YMR117C Component of the kinetochore-associated Ndc80 complex genetic 1 1 1 Negative Genetic
SRV2 YNL138W CAP (cyclase-associated protein) genetic 1 1 1 Negative Genetic
SGT1 YOR057W Cochaperone protein genetic 1 1 1 Negative Genetic
SEC23 YPR181C GTPase-activating protein, stimulates the GTPase activity of Sar1p genetic 1 1 1 Negative Genetic
YDL057W YDL057W Putative protein of unknown function genetic 1 1 1 Negative Genetic
UME6 YDR207C Rpd3L histone deacetylase complex subunit genetic 1 1 1 Negative Genetic
SSF1 YHR066W Constituent of 66S pre-ribosomal particles genetic 1 1 1 Negative Genetic
TPT1 YOL102C tRNA 2'-phosphotransferase that catalyzes final step in tRNA splicing genetic 1 1 1 Positive Genetic
UBA1 YKL210W Ubiquitin activating enzyme (E1) genetic 1 1 1 Synthetic Growth Defect
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 1 1 1 Negative Genetic
RVB2 YPL235W ATP-dependent DNA helicase, also known as reptin physical 1 1 1 Reconstituted Complex
EAF1 YDR359C Component of the NuA4 histone acetyltransferase complex genetic 1 1 1 Dosage Lethality
NIP7 YPL211W Nucleolar protein required for 60S ribosome subunit biogenesis genetic 1 1 1 Negative Genetic
NOP2 YNL061W rRNA m5C methyltransferase genetic 1 1 1 Negative Genetic
RIC1 YLR039C Protein involved in retrograde transport to the cis-Golgi network genetic 1 1 1 Positive Genetic
NSR1 YGR159C Nucleolin, nucleolar protein that binds nuclear localization sequences physical 1 1 1 Affinity Capture-MS
CDC48 YDL126C AAA ATPase with protein-unfoldase activity genetic 1 1 1 Negative Genetic
RPA34 YJL148W RNA polymerase I subunit A34.5 genetic 1 1 1 Negative Genetic
RPC34 YNR003C RNA polymerase III subunit C34 genetic 1 1 1 Negative Genetic
CBC2 YPL178W Small subunit of the heterodimeric cap binding complex with Sto1p genetic 1 1 1 Negative Genetic
NOP12 YOL041C Nucleolar protein involved in pre-25S rRNA processing genetic 1 1 1 Negative Genetic
RPN10 YHR200W Proteasome polyubiquitin receptor genetic 1 1 1 Negative Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
BET3 YKR068C Core component of transport protein particle (TRAPP) complexes I-III genetic 1 1 1 Negative Genetic
BNI1 YNL271C Formin physical 1 1 1 Reconstituted Complex
AVO1 YOL078W Component of the membrane-bound TORC2 complex genetic 1 1 1 Positive Genetic
CKS1 YBR135W Cyclin-dependent protein kinase regulatory subunit and adaptor genetic 1 1 1 Positive Genetic
CTK1 YKL139W Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) genetic 1 1 1 Negative Genetic
DYN1 YKR054C Cytoplasmic heavy chain dynein genetic 1 1 1 Negative Genetic
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family physical 1 1 1 Affinity Capture-MS
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family genetic 1 1 1 Negative Genetic
KAP114 YGL241W Karyopherin, responsible for nuclear import of specific proteins genetic 1 1 1 Negative Genetic
APM1 YPL259C Mu1-like medium subunit of the AP-1 complex genetic 1 1 1 Negative Genetic
POL1 YNL102W Catalytic subunit of the DNA polymerase I alpha-primase complex genetic 1 1 1 Negative Genetic
POL12 YBL035C B subunit of DNA polymerase alpha-primase complex genetic 1 1 1 Negative Genetic
BLM10 YFL007W Proteasome activator genetic 1 1 1 Negative Genetic
MRPL38 YKL170W Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
DAM1 YGR113W Essential subunit of the Dam1 complex (aka DASH complex) genetic 1 1 1 Negative Genetic
NAB3 YPL190C RNA-binding protein, subunit of Nrd1 complex (Nrd1p-Nab3p-Sen1p) genetic 1 1 1 Negative Genetic
NET1 YJL076W Core subunit of the RENT complex physical 1 1 1 Affinity Capture-MS
RSE1 YML049C Protein involved in pre-mRNA splicing physical 1 1 1 Affinity Capture-MS
REG1 YDR028C Regulatory subunit of type 1 protein phosphatase Glc7p physical 1 1 1 Affinity Capture-MS
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes physical 1 1 1 Affinity Capture-MS
BCK1 YJL095W MAPKKK acting in the protein kinase C signaling pathway genetic 1 1 1 Dosage Growth Defect
BRE2 YLR015W Subunit of COMPASS (Set1C) complex genetic 1 1 1 Negative Genetic
FAR11 YNL127W Protein involved in recovery from cell cycle arrest genetic 1 1 1 Positive Genetic
ACH1 YBL015W Protein with CoA transferase activity physical 1 1 1 Reconstituted Complex
ASA1 YPR085C Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Negative Genetic
CDC53 YDL132W Cullin genetic 1 1 1 Negative Genetic
NOP6 YDL213C rRNA-binding protein required for 40S ribosomal subunit biogenesis genetic 1 1 1 Negative Genetic
PMA1 YGL008C Plasma membrane P2-type H+-ATPase physical 1 1 1 Affinity Capture-MS
HXT6 YDR343C High-affinity glucose transporter physical 1 1 1 Affinity Capture-MS
PMA2 YPL036W Plasma membrane H+-ATPase physical 1 1 1 Affinity Capture-MS
GLC8 YMR311C Regulatory subunit of protein phosphatase 1 (Glc7p) genetic 1 1 1 Negative Genetic
QCR2 YPR191W Subunit 2 of ubiquinol cytochrome-c reductase (Complex III) genetic 1 1 1 Negative Genetic
LTP1 YPR073C Protein phosphotyrosine phosphatase of unknown cellular role genetic 1 1 1 Negative Genetic
NTF2 YER009W Nuclear envelope protein genetic 1 1 1 Negative Genetic
CTF13 YMR094W Subunit of the CBF3 complex genetic 1 1 1 Negative Genetic
CIN8 YEL061C Bipolar kinesin motor protein genetic 1 1 1 Negative Genetic
RIM11 YMR139W Protein kinase physical 1 1 1 Reconstituted Complex
ARP1 YHR129C Actin-related protein of the dynactin complex genetic 1 1 1 Negative Genetic
CIT2 YCR005C Citrate synthase, peroxisomal isozyme involved in glyoxylate cycle genetic 1 1 1 Negative Genetic
CSM1 YCR086W Nucleolar protein that mediates homolog segregation during meiosis I genetic 1 1 1 Negative Genetic
MOB2 YFL034C-B Activator of Cbk1p kinase genetic 1 1 1 Negative Genetic
PKC1 YBL105C Protein serine/threonine kinase genetic 1 1 1 Positive Genetic
LAA2 YBL010C Clathrin adaptor (adaptin) accessory protein physical 1 1 1 Affinity Capture-MS
CST6 YIL036W Basic leucine zipper (bZIP) transcription factor from ATF/CREB family genetic 1 1 1 Negative Genetic
RTG1 YOL067C Transcription factor (bHLH) involved in interorganelle communication genetic 1 1 1 Negative Genetic
BUB1 YGR188C Protein kinase involved in the cell cycle checkpoint into anaphase genetic 1 1 1 Synthetic Lethality
EXO1 YOR033C 5'-3' exonuclease and flap-endonuclease genetic 1 1 1 Positive Genetic
MAD1 YGL086W Coiled-coil protein involved in spindle-assembly checkpoint genetic 1 1 1 Synthetic Lethality
MDM12 YOL009C Mitochondrial outer membrane protein, ERMES complex subunit genetic 1 1 1 Negative Genetic
CCZ1 YBR131W Subunit of a heterodimeric guanine nucleotide exchange factor (GEF) genetic 1 1 1 Positive Genetic
HSF1 YGL073W Trimeric heat shock transcription factor genetic 1 1 1 Negative Genetic
BCH1 YMR237W Member of the ChAPs family (Chs5p-Arf1p-binding proteins) genetic 1 1 1 Negative Genetic
NIP100 YPL174C Large subunit of the dynactin complex physical 1 1 1 Affinity Capture-MS
PFY1 YOR122C Profilin genetic 1 1 1 Positive Genetic
MNN11 YJL183W Subunit of a Golgi mannosyltransferase complex genetic 1 1 1 Negative Genetic
ARL3 YPL051W ARF-like small GTPase of the RAS superfamily genetic 1 1 1 Negative Genetic
EAF6 YJR082C Subunit of the NuA4 acetyltransferase complex genetic 1 1 1 Dosage Growth Defect
PDR11 YIL013C ATP-binding cassette (ABC) transporter genetic 1 1 1 Negative Genetic
RPL43B YJR094W-A Ribosomal 60S subunit protein L43B genetic 1 1 1 Negative Genetic
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 1 1 1 Negative Genetic
PMR1 YGL167C High affinity Ca2+/Mn2+ P-type ATPase genetic 1 1 1 Negative Genetic
OLE1 YGL055W Delta(9) fatty acid desaturase genetic 1 1 1 Negative Genetic
RPL37A YLR185W Ribosomal 60S subunit protein L37A genetic 1 1 1 Negative Genetic
MDM36 YPR083W Mitochondrial protein genetic 1 1 1 Negative Genetic
ALT1 YLR089C Alanine transaminase (glutamic pyruvic transaminase) genetic 1 1 1 Negative Genetic
RPL8B YLL045C Ribosomal 60S subunit protein L8A genetic 1 1 1 Negative Genetic
RPL17B YJL177W Ribosomal 60S subunit protein L17B genetic 1 1 1 Negative Genetic
RPL6B YLR448W Ribosomal 60S subunit protein L6B genetic 1 1 1 Negative Genetic
ARO2 YGL148W Bifunctional chorismate synthase and flavin reductase genetic 1 1 1 Negative Genetic
AIM11 YER093C-A Protein of unknown function genetic 1 1 1 Negative Genetic
GPI12 YMR281W ER membrane protein involved in the second step of GPI anchor assembly genetic 1 1 1 Negative Genetic
CYT1 YOR065W Cytochrome c1 genetic 1 1 1 Negative Genetic
GPI19 YDR437W Subunit of GPI-GlcNAc transferase involved in synthesis of GlcNAc-PI genetic 1 1 1 Negative Genetic
GIS1 YDR096W Histone demethylase and transcription factor physical 1 1 1 Affinity Capture-MS
NTG2 YOL043C DNA N-glycosylase and apurinic/apyrimidinic (AP) lyase genetic 1 1 1 Negative Genetic
FLC1 YPL221W Flavin adenine dinucleotide transporter genetic 1 1 1 Negative Genetic
DYN3 YMR299C Dynein light intermediate chain (LIC) genetic 1 1 1 Negative Genetic
CDC8 YJR057W Nucleoside monophosphate and nucleoside diphosphate kinase genetic 1 1 1 Negative Genetic
ATO2 YNR002C Putative transmembrane protein involved in export of ammonia genetic 1 1 1 Negative Genetic
MDM35 YKL053C-A Mitochondrial intermembrane space protein genetic 1 1 1 Negative Genetic
MDL2 YPL270W Mitochondrial inner membrane half-type ABC transporter genetic 1 1 1 Negative Genetic
APS3 YJL024C Small subunit of the clathrin-associated adaptor complex AP-3 genetic 1 1 1 Negative Genetic
CSS3 YOL159C Protein of unknown function, secreted when constitutively expressed genetic 1 1 1 Negative Genetic
RPS30A YLR287C-A Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
SDH9 YJL045W Minor succinate dehydrogenase isozyme genetic 1 1 1 Negative Genetic